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Gene: PROM1 (prominin 1) Homo sapiens
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Symbol: PROM1
Name: prominin 1
Description: Exhibits actinin binding activity and cadherin binding activity. Involved in several processes, including glomerular epithelial cell differentiation; photoreceptor cell maintenance; and positive regulation of nephron tubule epithelial cell differentiation. Localizes to several cellular components, including endoplasmic reticulum-Golgi intermediate compartment; extracellular exosome; and photoreceptor outer segment membrane. Implicated in cone-rod dystrophy 12 and retinitis pigmentosa 41.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AC133; antigen AC133; CD133; CORD12; hematopoietic stem cell antigen; hProminin; macular dystrophy, retinal 2; MCDR2; MSTP061; prominin-1; prominin-like 1; prominin-like protein 1; PROML1; RP41; Stargardt disease 4 (autosomal dominant); STGD4
Orthologs:
Mus musculus (house mouse) : Prom1 (prominin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prom1 (prominin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prom1 (prominin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PROM1 (prominin 1)
Canis lupus familiaris (dog) : PROM1 (prominin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prom1 (prominin 1)
Sus scrofa (pig) : PROM1 (prominin 1)
Chlorocebus sabaeus (African green monkey) : PROM1 (prominin 1)
Heterocephalus glaber (naked mole-rat) : Prom1 (prominin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl415,963,076 - 16,084,378 (-)EnsemblGRCh38hg38GRCh38
GRCh38415,968,226 - 16,084,059 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37415,969,849 - 16,085,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36415,578,955 - 15,686,664 (-)NCBINCBI36hg18NCBI36
Build 34415,646,125 - 15,753,835NCBI
Celera416,434,397 - 16,550,164 (-)NCBI
Cytogenetic Map4p15.32NCBI
HuRef415,319,438 - 15,435,190 (-)NCBIHuRef
CHM1_1415,967,639 - 16,083,574 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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