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Gene: ACACA (acetyl-CoA carboxylase alpha) Homo sapiens
Symbol: ACACA
Name: acetyl-CoA carboxylase alpha
RGD ID: 736015
Description: Exhibits acetyl-CoA carboxylase activity and identical protein binding activity. Predicted to be involved in acetyl-CoA metabolic process; fatty acid biosynthetic process; and protein homotetramerization. Localizes to actin cytoskeleton; cytosol; and fibrillar center.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACAC; ACACAD; ACC; ACC-alpha; ACC1; ACCA; acetyl-CoA carboxylase 1; acetyl-CoA carboxylase-alpha; acetyl-Coenzyme A carboxylase alpha
Mus musculus (house mouse) : Acaca (acetyl-Coenzyme A carboxylase alpha)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acaca (acetyl-CoA carboxylase alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acaca (acetyl-CoA carboxylase alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ACACA (acetyl-CoA carboxylase alpha)
Canis lupus familiaris (dog) : ACACA (acetyl-CoA carboxylase alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acaca (acetyl-CoA carboxylase alpha)
Sus scrofa (pig) : ACACA (acetyl-CoA carboxylase alpha)
Chlorocebus sabaeus (African green monkey) : ACACA (acetyl-CoA carboxylase alpha)
Heterocephalus glaber (naked mole-rat) : Acaca (acetyl-CoA carboxylase alpha)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1737,084,992 - 37,406,836 (-)EnsemblGRCh38hg38GRCh38
GRCh381737,084,992 - 37,406,836 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371735,441,927 - 35,766,902 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361732,516,040 - 32,841,015 (-)NCBINCBI36hg18NCBI36
Build 341732,516,039 - 32,841,015NCBI
Celera1732,264,387 - 32,589,361 (-)NCBI
Cytogenetic Map17q12NCBI
HuRef1731,594,734 - 31,704,859 (-)NCBIHuRef
HuRef1731,378,027 - 31,583,939 (-)NCBIHuRef
CHM1_11735,476,555 - 35,798,374 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ACACA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736015
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.