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Gene: TTL (tubulin tyrosine ligase) Homo sapiens
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Symbol: TTL
Name: tubulin tyrosine ligase
Description: Exhibits tubulin-tyrosine ligase activity. Involved in C-terminal protein-tyrosinylation; positive regulation of mitotic cell cycle; and regulation of metaphase plate congression. Localizes to the cell.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410003M22Rik; MGC46235; tubulin--tyrosine ligase; tubulin-tyrosine ligase
Orthologs:
Mus musculus (house mouse) : Ttl (tubulin tyrosine ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ttl (tubulin tyrosine ligase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ttl (tubulin tyrosine ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : TTL (tubulin tyrosine ligase)
Canis lupus familiaris (dog) : TTL (tubulin tyrosine ligase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ttl (tubulin tyrosine ligase)
Sus scrofa (pig) : TTL (tubulin tyrosine ligase)
Chlorocebus sabaeus (African green monkey) : TTL (tubulin tyrosine ligase)
Heterocephalus glaber (naked mole-rat) : Ttl (tubulin tyrosine ligase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2112,482,156 - 112,541,739 (+)Ensembl
GRCh382112,482,127 - 112,541,739 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,239,743 - 113,290,223 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362112,956,214 - 113,006,694 (+)NCBINCBI36hg18NCBI36
Build 342112,956,128 - 113,006,212NCBI
Celera2106,625,279 - 106,675,764 (+)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2105,693,725 - 105,744,724 (+)NCBIHuRef
CHM1_12113,243,890 - 113,294,368 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on TTL
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732112
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.