Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: KANK2 (KN motif and ankyrin repeat domains 2) Homo sapiens
Analyze
Symbol: KANK2
Name: KN motif and ankyrin repeat domains 2
Description: This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANKRD25; ankyrin repeat domain 25; ankyrin repeat domain-containing protein 25; DKFZp434N161; FLJ20004; KIAA1518; kidney ankyrin repeat-containing protein 2; KN motif and ankyrin repeat domain-containing protein 2; matrix-remodeling-associated protein 3; matrix-remodelling associated 3; MGC119707; MXRA3; NPHS16; PPKWH; SIP; SRC-1 interacting protein; SRC-1-interacting protein; SRC-interacting protein; SRC1-interacting protein
Orthologs:
Mus musculus (house mouse) : Kank2 (KN motif and ankyrin repeat domains 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kank2 (KN motif and ankyrin repeat domains 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kank2 (KN motif and ankyrin repeat domains 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KANK2 (KN motif and ankyrin repeat domains 2)
Canis lupus familiaris (dog) : KANK2 (KN motif and ankyrin repeat domains 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kank2 (KN motif and ankyrin repeat domains 2)
Sus scrofa (pig) : KANK2 (KN motif and ankyrin repeat domains 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381911,164,267 - 11,197,545 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,274,943 - 11,308,243 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,135,946 - 11,167,496 (-)NCBINCBI36hg18NCBI36
Build 341911,135,946 - 11,167,496NCBI
Celera1911,169,761 - 11,203,056 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1910,851,580 - 10,884,321 (-)NCBIHuRef
CHM1_11911,276,193 - 11,309,454 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KANK2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1352192
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.