Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Zbtb7c (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ZBTB7C mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | affects expression | ISO | Zbtb7c (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ZBTB7C mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of ZBTB7C mRNA | CTD | PMID:18936297 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of ZBTB7C mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZBTB7C mRNA | CTD | PMID:28922406 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of ZBTB7C mRNA | CTD | PMID:30851411 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Zbtb7c (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of ZBTB7C exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Zbtb7c (Mus musculus) | 6480464 | bisphenol S affects the methylation of ZBTB7C gene | CTD | PMID:31683443 | 4-hydroxynon-2-enal | increases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in increased expression of ZBTB7C mRNA | CTD | PMID:19191707 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of ZBTB7C intron and Aflatoxin B1 results in increased methylation of ZBTB7C polyA tail | CTD | PMID:30157460 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of ZBTB7C mRNA | CTD | PMID:32234424 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of ZBTB7C promoter | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | EXP | | 6480464 | aflatoxin B2 results in increased methylation of ZBTB7C polyA tail | CTD | PMID:30157460 | all-trans-retinoic acid | multiple interactions | ISO | Zbtb7c (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZBTB7C mRNA | CTD | PMID:36189433 | all-trans-retinoic acid | increases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | Tretinoin results in increased expression of ZBTB7C mRNA | CTD | PMID:36189433 | arsane | multiple interactions | EXP | | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ZBTB7C mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | EXP | | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ZBTB7C mRNA | CTD | PMID:32525701 | benzo[a]pyrene | increases methylation | ISO | Zbtb7c (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of ZBTB7C intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | EXP | | 6480464 | Benzo(a)pyrene results in decreased methylation of ZBTB7C 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of ZBTB7C 3' UTR more ... | CTD | PMID:27901495 and PMID:30157460 | bisphenol A | increases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | bisphenol A results in increased expression of ZBTB7C mRNA | CTD | PMID:26063408 and PMID:32156529 | bisphenol A | decreases methylation | EXP | | 6480464 | bisphenol A results in decreased methylation of ZBTB7C gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] affects the methylation of ZBTB7C gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ZBTB7C mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of ZBTB7C gene | CTD | PMID:28505145 | bisphenol A | increases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ZBTB7C mRNA | CTD | PMID:25181051 | bromobenzene | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | bromobenzene results in decreased expression of ZBTB7C mRNA | CTD | PMID:32479839 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZBTB7C gene] | CTD | PMID:28238834 | cisplatin | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | Cisplatin results in decreased expression of ZBTB7C mRNA | CTD | PMID:22023808 | Cuprizon | increases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of ZBTB7C mRNA | CTD | PMID:26577399 | dexamethasone | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of ZBTB7C mRNA | CTD | PMID:22733784 | dibutyl phthalate | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of ZBTB7C mRNA | CTD | PMID:21266533 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of ZBTB7C mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of ZBTB7C mRNA | CTD | PMID:29391264 | epoxiconazole | increases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | epoxiconazole results in increased expression of ZBTB7C mRNA | CTD | PMID:35436446 | ethanol | affects expression | ISO | Zbtb7c (Mus musculus) | 6480464 | Ethanol affects the expression of ZBTB7C mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ZBTB7C mRNA | CTD | PMID:25629700 | fulvestrant | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Fulvestrant] affects the methylation of ZBTB7C gene | CTD | PMID:31601247 | furan | increases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | furan results in increased expression of ZBTB7C mRNA | CTD | PMID:27387713 | gentamycin | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of ZBTB7C mRNA | CTD | PMID:33387578 | inulin | multiple interactions | ISO | Zbtb7c (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ZBTB7C mRNA | CTD | PMID:36331819 | lead(0) | affects expression | EXP | | 6480464 | Lead affects the expression of ZBTB7C mRNA | CTD | PMID:28903495 | manganese(II) chloride | increases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | manganese chloride results in increased expression of ZBTB7C mRNA | CTD | PMID:28801915 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Zbtb7c (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of ZBTB7C mRNA | CTD | PMID:36189433 | O-methyleugenol | decreases expression | EXP | | 6480464 | methyleugenol results in decreased expression of ZBTB7C mRNA | CTD | PMID:32234424 | perfluorobutyric acid | decreases expression | EXP | | 6480464 | perfluorobutyric acid results in decreased expression of ZBTB7C mRNA | CTD | PMID:36251517 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Zbtb7c (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ZBTB7C mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ZBTB7C mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | affects expression | EXP | | 6480464 | perfluorooctanoic acid affects the expression of ZBTB7C mRNA | CTD | PMID:36251517 | pirinixic acid | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ZBTB7C mRNA | CTD | PMID:23811191 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of ZBTB7C mRNA | CTD | PMID:30851411 | sodium arsenate | multiple interactions | EXP | | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ZBTB7C mRNA | CTD | PMID:32525701 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of ZBTB7C mRNA | CTD | PMID:34032870 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of ZBTB7C mRNA | CTD | PMID:31533062 | thioacetamide | decreases expression | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of ZBTB7C mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of ZBTB7C mRNA | CTD | PMID:23409001 | tributylstannane | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | tributyltin results in decreased expression of ZBTB7C mRNA | CTD | PMID:31939706 | triclosan | increases expression | EXP | | 6480464 | Triclosan results in increased expression of ZBTB7C mRNA | CTD | PMID:30510588 | triptonide | decreases expression | ISO | Zbtb7c (Mus musculus) | 6480464 | triptonide results in decreased expression of ZBTB7C mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of ZBTB7C gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | Zbtb7c (Mus musculus) | 6480464 | Valproic Acid affects the expression of ZBTB7C mRNA | CTD | PMID:17963808 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ZBTB7C mRNA | CTD | PMID:25979313 | vinclozolin | increases methylation | ISO | Zbtb7c (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of ZBTB7C gene | CTD | PMID:31079544 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Human Phenotype Annotations - ClinVar
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Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Biological Process
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Molecular Function
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Phenotype Annotations
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:1716694 | PMID:8889548 | PMID:9427755 | PMID:14702039 | PMID:17932560 | PMID:20467437 | PMID:21804610 | PMID:21873635 | PMID:22253232 | PMID:22331133 | PMID:23006423 | PMID:23456168 |
| PMID:26542693 | PMID:27646874 | PMID:28380382 | PMID:28571744 | PMID:32193444 | PMID:33946045 | PMID:33961781 | PMID:37121538 |
Genomics
Comparative Map Data
| ZBTB7C (Homo sapiens - human) |
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| Zbtb7c (Mus musculus - house mouse) |
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| Zbtb7c (Rattus norvegicus - Norway rat) |
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| Zbtb7c (Chinchilla lanigera - long-tailed chinchilla) |
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| ZBTB7C (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ZBTB7C (Canis lupus familiaris - dog) |
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| Zbtb7c (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ZBTB7C (Sus scrofa - pig) |
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| ZBTB7C (Chlorocebus sabaeus - green monkey) |
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| Zbtb7c (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in ZBTB7C
53 total Variants 
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