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Gene: CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1) Homo sapiens
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Symbol: CDK5R1
Name: cyclin dependent kinase 5 regulatory subunit 1
Description: Exhibits protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in protein phosphorylation and regulation of macromolecule biosynthetic process. Localizes to the nucleoplasm and perinuclear region of cytoplasm. Implicated in Alzheimer's disease. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDK5 activator 1; CDK5P35; CDK5R; cyclin-dependent kinase 5 activator 1; cyclin-dependent kinase 5 regulatory subunit 1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); MGC33831; NCK5A; neuronal CDK5 activator; p23; p25; p35; p35nck5a; regulatory partner for CDK5 kinase; tau protein kinase II 23kDa subunit; TPKII regulatory subunit
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381732,485,028 - 32,491,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371730,814,105 - 30,818,271 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361727,838,218 - 27,842,384 (+)NCBINCBI36hg18NCBI36
Build 341727,838,217 - 27,842,383NCBI
Celera1727,724,307 - 27,728,473 (+)NCBI
Cytogenetic Map17q11.2NCBI
HuRef1727,000,601 - 27,004,486 (+)NCBIHuRef
CHM1_11730,876,567 - 30,880,733 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDK5R1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733787
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.