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Gene: MSX1 (msh homeobox 1) Homo sapiens
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Symbol: MSX1
Name: msh homeobox 1
Description: Exhibits p53 binding activity and sequence-specific double-stranded DNA binding activity. Involved in several processes, including embryonic nail plate morphogenesis; face morphogenesis; and protein stabilization. Localizes to nucleoplasm. Implicated in cleft lip; cleft palate; orofacial cleft 5; tooth and nail syndrome; and tooth disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ECTD3; homeo box, msh-like 1; homeobox 7; homeobox protein Hox-7; homeobox protein MSX-1; HOX7; HYD1; msh homeo box 1; msh homeobox 1-like protein; msh homeobox homolog 1; STHAG1
Orthologs:
Mus musculus (house mouse) : Msx1 (msh homeobox 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Msx1 (msh homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msx1 (msh homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MSX1 (msh homeobox 1)
Canis lupus familiaris (dog) : MSX1 (msh homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msx1 (msh homeobox 1)
Sus scrofa (pig) : MSX1 (msh homeobox 1)
Chlorocebus sabaeus (African green monkey) : MSX1 (msh homeobox 1)
Heterocephalus glaber (naked mole-rat) : Msx1 (msh homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl44,859,665 - 4,863,936 (+)EnsemblGRCh38hg38GRCh38
GRCh3844,859,665 - 4,863,936 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3744,861,392 - 4,865,663 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3644,912,293 - 4,916,564 (+)NCBINCBI36hg18NCBI36
Build 3444,979,477 - 4,983,530NCBI
Celera44,758,413 - 4,762,671 (+)NCBI
Cytogenetic Map4p16.2NCBI
HuRef44,797,648 - 4,801,917 (+)NCBIHuRef
CHM1_144,859,330 - 4,863,591 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MSX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731562
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.