CCR1 (C-C motif chemokine receptor 1) - Rat Genome Database

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Gene: CCR1 (C-C motif chemokine receptor 1) Homo sapiens
Analyze
Symbol: CCR1
Name: C-C motif chemokine receptor 1
RGD ID: 1349625
HGNC Page HGNC:1602
Description: Enables C-C chemokine binding activity; C-C chemokine receptor activity; and phosphatidylinositol phospholipase C activity. Involved in several processes, including monocyte chemotaxis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of monocyte chemotaxis. Located in external side of plasma membrane. Implicated in allergic contact dermatitis and rheumatoid arthritis. Biomarker of Alzheimer's disease; Lewy body dementia; cerebral amyloid angiopathy; coronary artery disease; and liver cirrhosis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C-C chemokine receptor type 1; C-C CKR-1; CC-CKR-1; CCR-1; CD191; chemokine (C-C motif) receptor 1; CKR-1; CKR1; CMKBR1; HM145; LD78 receptor; macrophage inflammatory protein 1-alpha receptor; MIP-1alpha-R; MIP1aR; RANTES receptor; RANTES-R; SCYAR1
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,201,711 - 46,208,313 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,201,711 - 46,208,313 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,243,202 - 46,249,804 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,218,204 - 46,224,836 (-)NCBINCBI36Build 36hg18NCBI36
Build 34346,218,203 - 46,224,836NCBI
Celera346,180,543 - 46,187,174 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,286,913 - 46,293,545 (-)NCBIHuRef
CHM1_1346,193,211 - 46,199,842 (-)NCBICHM1_1
T2T-CHM13v2.0346,217,573 - 46,224,175 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-arachidonoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP)
asperentin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
carbofuran  (ISO)
carbon nanotube  (ISO)
CGP 52608  (EXP)
choline  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (EXP)
cyproterone acetate  (EXP)
deoxynivalenol  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (EXP)
diclofenac  (ISO)
Didecyldimethylammonium  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dorsomorphin  (EXP)
doxorubicin  (ISO)
endosulfan  (ISO)
ethanol  (ISO)
folic acid  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (EXP)
inulin  (ISO)
irinotecan  (EXP)
isoprenaline  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (EXP)
mercury dichloride  (ISO)
methyl methanesulfonate  (EXP)
mevalonic acid  (EXP)
microcystin-LR  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
neoechinulin A  (ISO)
nickel atom  (EXP)
nickel sulfate  (EXP)
nitrobenzenes  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
sarin  (EXP)
SB 431542  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sodium dichromate  (EXP)
sotorasib  (EXP)
sterigmatocystin  (ISO)
styrene  (EXP)
succimer  (ISO)
tamibarotene  (EXP)
testosterone enanthate  (EXP)
tetrachloromethane  (ISO)
tetradecane  (ISO)
Theaflavin 3,3'-digallate  (EXP)
thioacetamide  (ISO)
topotecan  (ISO)
trametinib  (EXP)
trans-caffeic acid  (ISO)
tributylstannane  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (EXP,ISO)
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
AA amyloidosis  (IAGP)
Abdominal pain  (IAGP)
Abnormal blistering of the skin  (IAGP)
Abnormal myocardium morphology  (IAGP)
Abnormal pyramidal sign  (IAGP)
Acne  (IAGP)
Anorexia  (IAGP)
Aortic regurgitation  (IAGP)
Arterial thrombosis  (IAGP)
Arthralgia  (IAGP)
Arthritis  (IAGP)
Ataxia  (IAGP)
Atypical behavior  (IAGP)
Avascular necrosis  (IAGP)
Blindness  (IAGP)
Cataract  (IAGP)
Cerebral ischemia  (IAGP)
Confusion  (IAGP)
Cranial nerve paralysis  (IAGP)
Developmental regression  (IAGP)
Diarrhea  (IAGP)
Elevated circulating C-reactive protein concentration  (IAGP)
Elevated erythrocyte sedimentation rate  (IAGP)
Endocarditis  (IAGP)
Epididymitis  (IAGP)
Erythema nodosum  (IAGP)
Fatigue  (IAGP)
Fever  (IAGP)
Gait disturbance  (IAGP)
Gangrene  (IAGP)
Gastrointestinal hemorrhage  (IAGP)
Genital ulcers  (IAGP)
Glomerulonephritis  (IAGP)
Glomerulopathy  (IAGP)
Headache  (IAGP)
Hemiparesis  (IAGP)
Hemoptysis  (IAGP)
Hyperreflexia  (IAGP)
Immunologic hypersensitivity  (IAGP)
Increased inflammatory response  (IAGP)
Increased intracranial pressure  (IAGP)
Infectious encephalitis  (IAGP)
Irritability  (IAGP)
Keratoconjunctivitis sicca  (IAGP)
Lymphadenopathy  (IAGP)
Malabsorption  (IAGP)
Memory impairment  (IAGP)
Meningitis  (IAGP)
Migraine  (IAGP)
Mitral regurgitation  (IAGP)
Myalgia  (IAGP)
Myocardial infarction  (IAGP)
Myocarditis  (IAGP)
Myositis  (IAGP)
Nausea and vomiting  (IAGP)
Non-infectious meningitis  (IAGP)
Nongranulomatous uveitis  (IAGP)
Optic neuritis  (IAGP)
Oral ulcer  (IAGP)
Orchitis  (IAGP)
Pancreatitis  (IAGP)
Panuveitis  (IAGP)
Papule  (IAGP)
Paresthesia  (IAGP)
Pericarditis  (IAGP)
Photophobia  (IAGP)
Pleural effusion  (IAGP)
Pleuritis  (IAGP)
Positive pathergy test  (IAGP)
Pulmonary embolism  (IAGP)
Pulmonary infiltrates  (IAGP)
Pustule  (IAGP)
Recurrent aphthous stomatitis  (IAGP)
Recurrent fever  (IAGP)
Renal insufficiency  (IAGP)
Retinopathy  (IAGP)
Retrobulbar optic neuritis  (IAGP)
Seizure  (IAGP)
Splenomegaly  (IAGP)
Subcutaneous nodule  (IAGP)
Superficial thrombophlebitis  (IAGP)
Vasculitis  (IAGP)
Venous thrombosis  (IAGP)
Vertigo  (IAGP)
Weight loss  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Expression of CC chemokines and their receptors in the eye in autoimmune anterior uveitis associated with EAE. Adamus G, etal., Invest Ophthalmol Vis Sci. 2001 Nov;42(12):2894-903.
2. CCL3/MIP-1alpha is pro-inflammatory in murine T cell-mediated hepatitis by recruiting CCR1-expressing CD4(+) T cells to the liver. Ajuebor MN, etal., Eur J Immunol. 2004 Oct;34(10):2907-18.
3. Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo. Amat M, etal., Br J Pharmacol. 2006 Nov;149(6):666-75. Epub 2006 Oct 3.
4. Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice. Anders HJ, etal., J Am Soc Nephrol. 2004 Jun;15(6):1504-13.
5. Functional antagonism of chemokine receptor CCR1 reduces mortality in acute pneumovirus infection in vivo. Bonville CA, etal., J Virol. 2004 Aug;78(15):7984-9.
6. Gene expression profiles at different stages of collagen-induced arthritis. Booth G, etal., Autoimmunity. 2008 Nov;41(7):512-21.
7. Evaluation of the effect of the specific CCR1 antagonist CP-481715 on the clinical and cellular responses observed following epicutaneous nickel challenge in human subjects. Borregaard J, etal., Contact Dermatitis. 2008 Oct;59(4):212-9.
8. Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice. Carpenter KJ, etal., Br J Pharmacol. 2005 Aug;145(8):1160-72.
9. CCR1/CCL5 (RANTES) receptor-ligand interactions modulate allogeneic T-cell responses and graft-versus-host disease following stem-cell transplantation. Choi SW, etal., Blood. 2007 Nov 1;110(9):3447-55. Epub 2007 Jul 19.
10. Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease. Eltayeb S, etal., J Neuroimmunol. 2003 Sep;142(1-2):75-85.
11. Expression of cytokine signaling genes in morbidly obese patients with non-alcoholic steatohepatitis and hepatic fibrosis. Estep JM, etal., Obes Surg. 2009 May;19(5):617-24. Epub 2009 Mar 12.
12. The human specific CCR1 antagonist CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice. Gladue RP, etal., J Immunol. 2006 Mar 1;176(5):3141-8.
13. Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice. Glass WG, etal., J Immunol. 2004 Sep 15;173(6):4030-9. doi: 10.4049/jimmunol.173.6.4030.
14. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
15. CCR1 is an early and specific marker of Alzheimer's disease. Halks-Miller M, etal., Ann Neurol. 2003 Nov;54(5):638-46.
16. Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis. Haringman JJ, etal., Ann Rheum Dis. 2003 Aug;62(8):715-21.
17. A new mouse model of lung allergy induced by the spores of Alternaria alternata and Cladosporium herbarum molds. Havaux X, etal., Clin Exp Immunol. 2005 Feb;139(2):179-88.
18. Treatment with BX471, a CC chemokine receptor 1 antagonist, attenuates systemic inflammatory response during sepsis. He M, etal., Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1173-80. Epub 2007 Jan 18.
19. Treatment with BX471, a nonpeptide CCR1 antagonist, protects mice against acute pancreatitis-associated lung injury by modulating neutrophil recruitment. He M, etal., Pancreas. 2007 Mar;34(2):233-41.
20. CCR1 deficiency increases susceptibility to fatal coronavirus infection of the central nervous system. Hickey MJ, etal., Viral Immunol. 2007 Dec;20(4):599-608.
21. Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis. Ji J, etal., Infect Immun. 2003 Aug;71(8):4278-88.
22. Respiratory syncytial virus-induced exaggeration of allergic airway disease is dependent upon CCR1-associated immune responses. John AE, etal., Eur J Immunol. 2005 Jan;35(1):108-16.
23. Spatiotemporal CCR1, CCL3(MIP-1alpha), CXCR4, CXCL12(SDF-1alpha) expression patterns in a rat spinal cord injury model of posttraumatic neuropathic pain. Knerlich-Lukoschus F, etal., J Neurosurg Spine. 2011 May;14(5):583-97. Epub 2011 Feb 18.
24. Treatment with Met-RANTES decreases bacterial translocation in experimental colitis. Kucuk C, etal., Am J Surg. 2006 Jan;191(1):77-83.
25. Role of Erk1/2 activation in prion disease pathogenesis: absence of CCR1 leads to increased Erk1/2 activation and accelerated disease progression. LaCasse RA, etal., J Neuroimmunol. 2008 May 30;196(1-2):16-26. Epub 2008 Apr 8.
26. Ccr1 deficiency reduces inflammatory remodelling and preserves left ventricular function after myocardial infarction. Liehn EA, etal., J Cell Mol Med. 2008 Apr;12(2):496-506. Epub 2007 Dec 14.
27. Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis. Lionakis MS, etal., PLoS Pathog. 2012;8(8):e1002865. doi: 10.1371/journal.ppat.1002865. Epub 2012 Aug 16.
28. Genetic deficiency in the chemokine receptor CCR1 protects against acute Clostridium difficile toxin A enteritis in mice. Morteau O, etal., Gastroenterology. 2002 Mar;122(3):725-33.
29. Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease. Ninichuk V, etal., J Am Soc Nephrol. 2005 Apr;16(4):977-85. Epub 2005 Feb 16.
30. Evidences of the cooperative role of the chemokines CCL3, CCL4 and CCL5 and its receptors CCR1+ and CCR5+ in RANKL+ cell migration throughout experimental periodontitis in mice. Repeke CE, etal., Bone. 2010 Apr;46(4):1122-30. Epub 2010 Jan 4.
31. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
32. Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis. Shahrara S, etal., Arthritis Rheum. 2003 Dec;48(12):3568-83.
33. Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice. Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
34. Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase. Stroo I, etal., Int Immunol. 2010 Jun;22(6):433-42. Epub 2010 Apr 21.
35. Differential expression of the chemokine receptors CX3CR1 and CCR1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis. Sunnemark D, etal., Brain Pathol. 2003 Oct;13(4):617-29.
36. Hydroxymethylglutaryl coenzyme a reductase inhibitors down-regulate chemokines and chemokine receptors in patients with coronary artery disease. Waehre T, etal., J Am Coll Cardiol. 2003 May 7;41(9):1460-7.
37. Selective expression and cellular localization of pro-inflammatory chemokine ligand/receptor pairs in the sciatic nerves of a severe murine experimental autoimmune neuritis model of Guillain-Barre syndrome. Xia RH, etal., Neuropathol Appl Neurobiol. 2010 Aug;36(5):388-98. Epub 2010 May 25.
38. The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis. Yang X, etal., Am J Respir Cell Mol Biol. 2011 Jul;45(1):127-35. Epub 2010 Sep 24.
39. Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients. Zhou Z, etal., Cell Host Microbe. 2020 Jun 10;27(6):883-890.e2. doi: 10.1016/j.chom.2020.04.017. Epub 2020 May 4.
Additional References at PubMed
PMID:2834384   PMID:7505609   PMID:7545673   PMID:7594543   PMID:7679328   PMID:7683036   PMID:8011297   PMID:8530354   PMID:8626727   PMID:8631787   PMID:8699119   PMID:9115216  
PMID:9143512   PMID:9289016   PMID:9346309   PMID:9558365   PMID:9886417   PMID:10094132   PMID:10202040   PMID:10583963   PMID:10660125   PMID:10702689   PMID:10706735   PMID:10734056  
PMID:10770925   PMID:10910894   PMID:11085751   PMID:11110672   PMID:11116158   PMID:11449371   PMID:11470772   PMID:11804551   PMID:11832479   PMID:11920567   PMID:12070001   PMID:12085329  
PMID:12270118   PMID:12477932   PMID:12651617   PMID:12763925   PMID:12794150   PMID:14530297   PMID:14637022   PMID:15001559   PMID:15039444   PMID:15053339   PMID:15103513   PMID:15265234  
PMID:15337751   PMID:15474493   PMID:15489334   PMID:15548526   PMID:15764707   PMID:15927850   PMID:15950672   PMID:16182378   PMID:16226254   PMID:16323127   PMID:16621978   PMID:16837468  
PMID:16969502   PMID:17135764   PMID:17192849   PMID:17298994   PMID:17336272   PMID:17389578   PMID:17464174   PMID:17558413   PMID:17914560   PMID:18178867   PMID:18240029   PMID:18311140  
PMID:18559339   PMID:18577758   PMID:18587271   PMID:18972130   PMID:19017998   PMID:19423540   PMID:19553544   PMID:19603542   PMID:19664396   PMID:19687291   PMID:19693089   PMID:19913121  
PMID:20015385   PMID:20056178   PMID:20086017   PMID:20154287   PMID:20190752   PMID:20406964   PMID:20429924   PMID:20438785   PMID:20628086   PMID:20634891   PMID:20802378   PMID:20921899  
PMID:21148810   PMID:21403648   PMID:21873635   PMID:21942940   PMID:22007486   PMID:22104149   PMID:22650026   PMID:22727097   PMID:22829007   PMID:22842622   PMID:23054685   PMID:23125416  
PMID:23217400   PMID:23219091   PMID:23233369   PMID:23276697   PMID:23291587   PMID:23846739   PMID:23876400   PMID:24056371   PMID:24157267   PMID:24489825   PMID:24599574   PMID:24778447  
PMID:24990525   PMID:25487697   PMID:25986216   PMID:26097239   PMID:26186194   PMID:26341919   PMID:26472202   PMID:26501423   PMID:27046081   PMID:27234431   PMID:27492974   PMID:28192408  
PMID:28298427   PMID:28381538   PMID:28514442   PMID:28855206   PMID:28892735   PMID:28954264   PMID:29285854   PMID:29556615   PMID:29703961   PMID:29895319   PMID:29930254   PMID:30021884  
PMID:30409062   PMID:30567735   PMID:30720175   PMID:32174921   PMID:32296183   PMID:32463796   PMID:32768961   PMID:32777727   PMID:32967511   PMID:33147936   PMID:33361824   PMID:33961781  
PMID:35287505   PMID:35408790   PMID:35809272   PMID:36317881   PMID:37903056   PMID:38274805  


Genomics

Comparative Map Data
CCR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38346,201,711 - 46,208,313 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl346,201,711 - 46,208,313 (-)EnsemblGRCh38hg38GRCh38
GRCh37346,243,202 - 46,249,804 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,218,204 - 46,224,836 (-)NCBINCBI36Build 36hg18NCBI36
Build 34346,218,203 - 46,224,836NCBI
Celera346,180,543 - 46,187,174 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef346,286,913 - 46,293,545 (-)NCBIHuRef
CHM1_1346,193,211 - 46,199,842 (-)NCBICHM1_1
T2T-CHM13v2.0346,217,573 - 46,224,175 (-)NCBIT2T-CHM13v2.0
Ccr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,762,163 - 123,768,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9123,762,161 - 123,768,729 (-)EnsemblGRCm39 Ensembl
GRCm389123,962,126 - 123,968,692 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9123,962,124 - 123,968,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv379123,876,959 - 123,883,525 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369123,810,922 - 123,817,364 (-)NCBIMGSCv36mm8
Celera9125,030,694 - 125,037,264 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
Ccr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88132,433,711 - 132,439,266 (-)NCBIGRCr8
mRatBN7.28123,556,286 - 123,561,841 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx8129,152,874 - 129,158,441 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08127,352,003 - 127,357,570 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08125,170,253 - 125,175,808 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08132,996,646 - 133,002,201 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8132,996,649 - 133,002,201 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08132,147,926 - 132,153,481 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48128,693,658 - 128,699,213 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18128,713,397 - 128,718,950 (-)NCBI
Celera8122,658,153 - 122,663,708 (-)NCBICelera
Cytogenetic Map8q32NCBI
CCR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2246,164,661 - 46,171,362 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1346,169,429 - 46,176,130 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0346,107,526 - 46,114,229 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1347,213,167 - 47,219,832 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,214,688 - 47,215,755 (-)Ensemblpanpan1.1panPan2
CCR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,421,356 - 42,427,177 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,421,356 - 42,426,958 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,337,281 - 42,341,854 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02042,903,724 - 42,909,542 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2042,903,713 - 42,909,543 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12042,144,885 - 42,149,455 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,552,456 - 42,557,022 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02042,827,348 - 42,831,924 (+)NCBIUU_Cfam_GSD_1.0
LOC101964209
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,628,576 - 200,633,955 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936596177,812 - 183,186 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936596177,774 - 183,186 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,227,222 - 29,233,960 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,227,218 - 29,233,862 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,323,642 - 32,330,286 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,634,205 - 7,641,380 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041159,517,175 - 159,523,723 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101724812
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473074,826,659 - 74,827,726 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473074,822,848 - 74,828,614 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCR1
27 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 3p21.31-21.2(chr3:45879883-50749922)x4 copy number gain See cases [RCV000133650] Chr3:45879883..50749922 [GRCh38]
Chr3:45921375..50787353 [GRCh37]
Chr3:45896379..50762357 [NCBI36]
Chr3:3p21.31-21.2		 pathogenic
GRCh38/hg38 3p21.31(chr3:45691931-46277910)x3 copy number gain See cases [RCV000134890] Chr3:45691931..46277910 [GRCh38]
Chr3:45733423..46319401 [GRCh37]
Chr3:45708427..46294405 [NCBI36]
Chr3:3p21.31		 likely benign
GRCh37/hg19 3p22.2-21.31(chr3:37028313-49929220)x3 copy number gain See cases [RCV000240519] Chr3:37028313..49929220 [GRCh37]
Chr3:3p22.2-21.31		 likely pathogenic
GRCh37/hg19 3p21.31(chr3:46243839-46307968)x3 copy number gain See cases [RCV000446594] Chr3:46243839..46307968 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.674T>C (p.Ile225Thr) single nucleotide variant not specified [RCV004305559] Chr3:46203640 [GRCh38]
Chr3:46245131 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986) copy number gain See cases [RCV000512358] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61892-197851986)x3 copy number gain See cases [RCV000511055] Chr3:61892..197851986 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:60174-197948027)x3 copy number gain not provided [RCV000742133] Chr3:60174..197948027 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
GRCh37/hg19 3p26.3-q29(chr3:61495-197838262)x3 copy number gain not provided [RCV000742138] Chr3:61495..197838262 [GRCh37]
Chr3:3p26.3-q29		 pathogenic
NM_001295.3(CCR1):c.1014G>A (p.Arg338=) single nucleotide variant not provided [RCV000879638] Chr3:46203300 [GRCh38]
Chr3:46244791 [GRCh37]
Chr3:3p21.31		 benign
NM_001295.3(CCR1):c.903C>T (p.Tyr301=) single nucleotide variant not provided [RCV000951250] Chr3:46203411 [GRCh38]
Chr3:46244902 [GRCh37]
Chr3:3p21.31		 benign|likely benign
NM_001295.3(CCR1):c.996C>T (p.Ser332=) single nucleotide variant not provided [RCV000900211] Chr3:46203318 [GRCh38]
Chr3:46244809 [GRCh37]
Chr3:3p21.31		 likely benign
GRCh37/hg19 3p21.31-21.1(chr3:45153770-53878616) copy number gain not provided [RCV000767704] Chr3:45153770..53878616 [GRCh37]
Chr3:3p21.31-21.1		 pathogenic
NM_001295.3(CCR1):c.381G>A (p.Leu127=) single nucleotide variant not provided [RCV000974980] Chr3:46203933 [GRCh38]
Chr3:46245424 [GRCh37]
Chr3:3p21.31		 benign
NM_001295.3(CCR1):c.868G>A (p.Ala290Thr) single nucleotide variant not provided [RCV000908948] Chr3:46203446 [GRCh38]
Chr3:46244937 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.162G>C (p.Leu54=) single nucleotide variant not provided [RCV000880019] Chr3:46204152 [GRCh38]
Chr3:46245643 [GRCh37]
Chr3:3p21.31		 benign|likely benign
NM_001295.3(CCR1):c.438C>T (p.Thr146=) single nucleotide variant not provided [RCV000892555] Chr3:46203876 [GRCh38]
Chr3:46245367 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.476C>T (p.Ala159Val) single nucleotide variant not provided [RCV000885971] Chr3:46203838 [GRCh38]
Chr3:46245329 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.1067G>A (p.Ter356=) single nucleotide variant not provided [RCV000956091] Chr3:46203247 [GRCh38]
Chr3:46244738 [GRCh37]
Chr3:3p21.31		 benign
NM_001295.3(CCR1):c.871T>C (p.Tyr291His) single nucleotide variant not provided [RCV000956092] Chr3:46203443 [GRCh38]
Chr3:46244934 [GRCh37]
Chr3:3p21.31		 benign
NC_000003.11:g.(?_45435946)_(49137751_?)dup duplication Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome [RCV003116297] Chr3:45435946..49137751 [GRCh37]
Chr3:3p21.31		 uncertain significance
GRCh37/hg19 3p21.31(chr3:44948482-49115809)x1 copy number loss not provided [RCV002279744] Chr3:44948482..49115809 [GRCh37]
Chr3:3p21.31		 pathogenic
NM_001295.3(CCR1):c.257C>T (p.Thr86Met) single nucleotide variant not specified [RCV004114064] Chr3:46204057 [GRCh38]
Chr3:46245548 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.938G>A (p.Arg313Gln) single nucleotide variant not specified [RCV004232876] Chr3:46203376 [GRCh38]
Chr3:46244867 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.109C>A (p.Leu37Met) single nucleotide variant not specified [RCV004076565] Chr3:46204205 [GRCh38]
Chr3:46245696 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.742T>G (p.Phe248Val) single nucleotide variant not specified [RCV004091704] Chr3:46203572 [GRCh38]
Chr3:46245063 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.299T>C (p.Val100Ala) single nucleotide variant not specified [RCV004090369] Chr3:46204015 [GRCh38]
Chr3:46245506 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.955C>G (p.Arg319Gly) single nucleotide variant not specified [RCV004307601] Chr3:46203359 [GRCh38]
Chr3:46244850 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.1019G>T (p.Ser340Ile) single nucleotide variant not specified [RCV004268863] Chr3:46203295 [GRCh38]
Chr3:46244786 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.544A>T (p.Thr182Ser) single nucleotide variant not specified [RCV004325881] Chr3:46203770 [GRCh38]
Chr3:46245261 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.858G>A (p.Thr286=) single nucleotide variant not provided [RCV003433545] Chr3:46203456 [GRCh38]
Chr3:46244947 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.54T>C (p.Tyr18=) single nucleotide variant not provided [RCV003887491] Chr3:46204260 [GRCh38]
Chr3:46245751 [GRCh37]
Chr3:3p21.31		 likely benign
NM_001295.3(CCR1):c.105A>C (p.Gln35His) single nucleotide variant not specified [RCV004432950] Chr3:46204209 [GRCh38]
Chr3:46245700 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.840C>A (p.Asp280Glu) single nucleotide variant not specified [RCV004432955] Chr3:46203474 [GRCh38]
Chr3:46244965 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.172G>A (p.Val58Ile) single nucleotide variant not specified [RCV004432951] Chr3:46204142 [GRCh38]
Chr3:46245633 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.553C>T (p.Leu185Phe) single nucleotide variant not specified [RCV004432953] Chr3:46203761 [GRCh38]
Chr3:46245252 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.90G>C (p.Arg30Ser) single nucleotide variant not specified [RCV004432956] Chr3:46204224 [GRCh38]
Chr3:46245715 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.475G>T (p.Ala159Ser) single nucleotide variant not specified [RCV004432952] Chr3:46203839 [GRCh38]
Chr3:46245330 [GRCh37]
Chr3:3p21.31		 uncertain significance
NM_001295.3(CCR1):c.92C>A (p.Ala31Asp) single nucleotide variant not specified [RCV004604908] Chr3:46204222 [GRCh38]
Chr3:46245713 [GRCh37]
Chr3:3p21.31		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:596
Count of miRNA genes:486
Interacting mature miRNAs:522
Transcripts:ENST00000296140
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298487BFD1_HBody fluid distribution QTL 1 (human)3.94Body fluid distributionimpedance ratio33638071262380712Human
1298489RA4_HRheumatoid arthritis QTL 4 (human)0.0283Joint/bone inflammationrheumatoid arthritis33638071262380712Human
1643509BW293_HBody Weight QTL 293 (human)1.42Body weightBMI33638071262380712Human
2316061GLUCO194_HGlucose level QTL 194 (human)0.02Glucose level32338077449380774Human
2289308BW392_HBody weight QTL 392 (human)1.42Body weightBMI33638071262380712Human
407152811GWAS801787_Hrespiratory symptom measurement, COVID-19 QTL GWAS801787 (human)0.000008respiratory symptom measurement, COVID-19respiratory system measurement (CMO:0000094)34620278946202790Human

Markers in Region
RH124084  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,244,903 - 46,245,211UniSTSGRCh37
Build 36346,219,907 - 46,220,215RGDNCBI36
Celera346,182,246 - 46,182,554RGD
Cytogenetic Map3p21UniSTS
HuRef346,288,615 - 46,288,923UniSTS
TNG Radiation Hybrid Map329122.0UniSTS
PMC109444P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,245,507 - 46,245,803UniSTSGRCh37
Build 36346,220,511 - 46,220,807RGDNCBI36
Celera346,182,850 - 46,183,146RGD
Cytogenetic Map3p21UniSTS
HuRef346,289,219 - 46,289,515UniSTS
PMC135988P5  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,245,323 - 46,245,743UniSTSGRCh37
Build 36346,220,327 - 46,220,747RGDNCBI36
Celera346,182,666 - 46,183,086RGD
Cytogenetic Map3p21UniSTS
HuRef346,289,035 - 46,289,455UniSTS
CCR1_513  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,244,299 - 46,245,149UniSTSGRCh37
Build 36346,219,303 - 46,220,153RGDNCBI36
Celera346,181,642 - 46,182,492RGD
HuRef346,288,011 - 46,288,861UniSTS
D3S4499  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,244,624 - 46,245,197UniSTSGRCh37
Build 36346,219,628 - 46,220,201RGDNCBI36
Celera346,181,967 - 46,182,540RGD
Cytogenetic Map3p21UniSTS
HuRef346,288,336 - 46,288,909UniSTS
STS-D10925  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,243,680 - 46,243,946UniSTSGRCh37
Build 36346,218,684 - 46,218,950RGDNCBI36
Celera346,181,023 - 46,181,289RGD
Cytogenetic Map3p21UniSTS
HuRef346,287,393 - 46,287,658UniSTS
TNG Radiation Hybrid Map329113.0UniSTS
GeneMap99-GB4 RH Map3143.05UniSTS
G15924  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,243,672 - 46,243,840UniSTSGRCh37
Build 36346,218,676 - 46,218,844RGDNCBI36
Celera346,181,015 - 46,181,183RGD
Cytogenetic Map3p21UniSTS
HuRef346,287,385 - 46,287,552UniSTS
D3S3937  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,244,318 - 46,244,423UniSTSGRCh37
Build 36346,219,322 - 46,219,427RGDNCBI36
Celera346,181,661 - 46,181,766RGD
Cytogenetic Map3p21UniSTS
HuRef346,288,030 - 46,288,135UniSTS
Whitehead-YAC Contig Map3 UniSTS
CCR1_mf  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37346,244,400 - 46,245,104UniSTSGRCh37
Celera346,181,743 - 46,182,447UniSTS
HuRef346,288,112 - 46,288,816UniSTS
D3S3069  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3p21UniSTS
HuRef346,292,025 - 46,292,201UniSTS
Whitehead-YAC Contig Map3 UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2386 2785 2239 4830 1713 2215 5 616 1877 458 2175 7166 6385 30 3672 827 1690 1492 167 1

Sequence


Ensembl Acc Id: ENST00000296140   ⟹   ENSP00000296140
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl346,201,711 - 46,208,313 (-)Ensembl
RefSeq Acc Id: NM_001295   ⟹   NP_001286
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38346,201,711 - 46,208,313 (-)NCBI
GRCh37346,243,200 - 46,249,832 (-)ENTREZGENE
Build 36346,218,204 - 46,224,836 (-)NCBI Archive
HuRef346,286,913 - 46,293,545 (-)ENTREZGENE
CHM1_1346,193,211 - 46,199,842 (-)NCBI
T2T-CHM13v2.0346,217,573 - 46,224,175 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001286   ⟸   NM_001295
- UniProtKB: Q86VA9 (UniProtKB/Swiss-Prot),   P32246 (UniProtKB/Swiss-Prot),   Q5U003 (UniProtKB/TrEMBL),   A0A024R2P9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000296140   ⟸   ENST00000296140
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P32246-F1-model_v2 AlphaFold P32246 1-355 view protein structure

Promoters
RGD ID:6864184
Promoter ID:EPDNEW_H5257
Type:initiation region
Name:CCR1_1
Description:C-C motif chemokine receptor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38346,208,312 - 46,208,372EPDNEW
RGD ID:6800735
Promoter ID:HG_KWN:44754
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:UC010HJA.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36346,220,006 - 46,221,307 (-)MPROMDB
RGD ID:6800736
Promoter ID:HG_KWN:44755
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000257325
Position:
Human AssemblyChrPosition (strand)Source
Build 36346,224,634 - 46,225,134 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1602 AgrOrtholog
COSMIC CCR1 COSMIC
Ensembl Genes ENSG00000163823 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000296140 ENTREZGENE
  ENST00000296140.4 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000163823 GTEx
HGNC ID HGNC:1602 ENTREZGENE
Human Proteome Map CCR1 Human Proteome Map
InterPro Chemokine_CCR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:1230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 1230 ENTREZGENE
OMIM 601159 OMIM
PANTHER CELL ADHESION MOLECULE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10489:SF711 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26166 PharmGKB
PRINTS CCCHEMOKINER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CHEMOKINER1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024R2P9 ENTREZGENE
  CCR1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q5U003 ENTREZGENE, UniProtKB/TrEMBL
  Q86VA9 ENTREZGENE
UniProt Secondary A0A024R2P9 UniProtKB/TrEMBL
  Q86VA9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-21 CCR1  C-C motif chemokine receptor 1  CCR1  chemokine (C-C motif) receptor 1  Symbol and/or name change 5135510 APPROVED