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Gene: MRAP (melanocortin 2 receptor accessory protein) Homo sapiens
Symbol: MRAP
Name: melanocortin 2 receptor accessory protein
RGD ID: 1603024
Description: Exhibits identical protein binding activity and melanocortin receptor binding activity. Involved in negative regulation of protein localization to plasma membrane; protein localization to plasma membrane; and regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway. Localizes to endoplasmic reticulum and plasma membrane. Implicated in familial glucocorticoid deficiency.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B27; C21orf61; FALP; fat cell-specific low molecular weight protein; fat tissue-specific low MW protein; FGD2; GCCD2; melanocortin-2 receptor accessory protein
Mus musculus (house mouse) : Mrap (melanocortin 2 receptor accessory protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mrap (melanocortin 2 receptor accessory protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mrap (melanocortin 2 receptor accessory protein)
Pan paniscus (bonobo/pygmy chimpanzee) : MRAP (melanocortin 2 receptor accessory protein)
Canis lupus familiaris (dog) : MRAP (melanocortin 2 receptor accessory protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mrap (melanocortin 2 receptor accessory protein)
Sus scrofa (pig) : MRAP (melanocortin 2 receptor accessory protein)
Chlorocebus sabaeus (African green monkey) : MRAP (melanocortin 2 receptor accessory protein)
Heterocephalus glaber (naked mole-rat) : Mrap (melanocortin 2 receptor accessory protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2132,291,813 - 32,314,784 (+)EnsemblGRCh38hg38GRCh38
GRCh382132,291,813 - 32,314,784 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372133,664,124 - 33,687,095 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362132,585,995 - 32,608,966 (+)NCBINCBI36hg18NCBI36
Celera2118,847,645 - 18,870,696 (+)NCBI
Cytogenetic Map21q22.11NCBI
HuRef2119,073,352 - 19,095,865 (+)NCBIHuRef
CHM1_12133,225,857 - 33,248,911 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MRAP
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603024
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.