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Gene: MAPK12 (mitogen-activated protein kinase 12) Homo sapiens
Symbol: MAPK12
Name: mitogen-activated protein kinase 12
Description: Exhibits magnesium ion binding activity and protein serine/threonine kinase activity. Involved in myoblast differentiation and peptidyl-serine phosphorylation. Predicted to localize to the cytoplasm and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ERK-6; ERK3; ERK6; extracellular signal-regulated kinase 6; MAP kinase 12; MAP kinase p38 gamma; MAPK 12; mitogen-activated protein kinase 3; mitogen-activated protein kinase p38 gamma; P38GAMMA; PRKM12; SAPK-3; SAPK3; stress-activated protein kinase 3
Mus musculus (house mouse) : Mapk12 (mitogen-activated protein kinase 12)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mapk12 (mitogen-activated protein kinase 12)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk12 (mitogen-activated protein kinase 12)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK12 (mitogen-activated protein kinase 12)
Canis lupus familiaris (dog) : MAPK12 (mitogen-activated protein kinase 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk12 (mitogen-activated protein kinase 12)
Sus scrofa (pig) : MAPK12 (mitogen-activated protein kinase 12)
Chlorocebus sabaeus (green monkey) : MAPK12 (mitogen-activated protein kinase 12)
Heterocephalus glaber (naked mole-rat) : Mapk12 (mitogen-activated protein kinase 12)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2250,245,450 - 50,261,716 (-)Ensembl
GRCh382250,252,901 - 50,261,810 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372250,691,331 - 50,700,248 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,033,458 - 49,042,216 (-)NCBINCBI36hg18NCBI36
Build 342248,993,787 - 49,002,546NCBI
Celera2234,566,234 - 34,574,992 (-)NCBI
Cytogenetic Map22q13.33NCBI
HuRef2233,590,177 - 33,594,692 (-)NCBIHuRef
CHM1_12250,650,085 - 50,658,942 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MAPK12
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731716
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.