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Gene: SLC7A3 (solute carrier family 7 member 3) Homo sapiens
Symbol: SLC7A3
Name: solute carrier family 7 member 3
Description: Exhibits L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Involved in L-arginine import across plasma membrane; L-lysine import across plasma membrane; and L-ornithine import across plasma membrane. Localizes to plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATRC3; CAT-3; CAT3; cationic amino acid transporter 3; FLJ14541; MGC20687; solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; solute carrier family 7, member 3
Mus musculus (house mouse) : Slc7a3 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc7a3 (solute carrier family 7 member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc7a3 (solute carrier family 7 member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC7A3 (solute carrier family 7 member 3)
Canis lupus familiaris (dog) : SLC7A3 (solute carrier family 7 member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc7a3 (solute carrier family 7 member 3)
Sus scrofa (pig) : SLC7A3 (solute carrier family 7 member 3)
Chlorocebus sabaeus (African green monkey) : SLC7A3 (solute carrier family 7 member 3)
Heterocephalus glaber (naked mole-rat) : Slc7a3 (solute carrier family 7 member 3)
more info ...
Related Pseudogenes: AC011487.2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 EnsemblX70,925,579 - 70,931,125 (-)EnsemblGRCh38hg38GRCh38
GRCh38X70,925,579 - 70,931,096 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,145,429 - 70,150,975 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,062,154 - 70,067,684 (-)NCBINCBI36hg18NCBI36
Build 34X69,928,452 - 69,933,951NCBI
CeleraX70,499,018 - 70,504,564 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX63,965,473 - 63,969,918 (-)NCBIHuRef
CHM1_1X70,036,878 - 70,042,423 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC7A3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733970
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.