UPP1 (uridine phosphorylase 1) - Rat Genome Database

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Gene: UPP1 (uridine phosphorylase 1) Homo sapiens
Analyze
Symbol: UPP1
Name: uridine phosphorylase 1
RGD ID: 1313669
HGNC Page HGNC:12576
Description: Enables identical protein binding activity and uridine phosphorylase activity. Involved in uridine catabolic process. Located in nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: UDRPASE; UP; UPASE; UPase 1; UPP; urdPase 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38748,088,704 - 48,108,736 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl748,088,628 - 48,108,736 (+)EnsemblGRCh38hg38GRCh38
GRCh37748,128,301 - 48,148,333 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36748,094,880 - 48,114,855 (+)NCBINCBI36Build 36hg18NCBI36
Celera748,227,538 - 48,247,515 (+)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef748,013,948 - 48,033,924 (+)NCBIHuRef
CHM1_1748,132,055 - 48,152,030 (+)NCBICHM1_1
T2T-CHM13v2.0748,250,938 - 48,270,970 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2748,168,224 - 48,188,201 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UPP1Humanmiddle cerebral artery infarction  ISORGD:13055662317094mRNA, protein:increased expression:brain (rat)RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UPP1Humanlong QT syndrome  IAGPRGD:103954268554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:26132555
UPP1Humanpleomorphic xanthoastrocytoma  IAGPRGD:128590218554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UPP1Humanallergic contact dermatitis  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:16033404
UPP1Humanrespiratory allergy  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:24211530

1 to 20 of 189 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UPP1Human(S)-nicotine increases expressionEXP 6480464Nicotine results in increased expression of UPP1 mRNACTDPMID:23825647
UPP1Human17alpha-ethynylestradiol increases expressionISORGD:13136706480464Ethinyl Estradiol results in increased expression of UPP1 mRNACTDPMID:17942748
UPP1Human17alpha-ethynylestradiol increases expressionISORGD:13055666480464Ethinyl Estradiol results in increased expression of UPP1 mRNACTDPMID:17557909
UPP1Human17alpha-ethynylestradiol multiple interactionsISORGD:13136706480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UPP1 mRNACTDPMID:17942748
UPP1Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of UPP1 mRNACTDPMID:20106945|PMID:31614463
UPP1Human17beta-estradiol decreases expressionISORGD:13136706480464Estradiol results in decreased expression of UPP1 mRNACTDPMID:39298647
UPP1Human17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with Progesterone] results in decreased expression of UPP1 mRNACTDPMID:20660070
UPP1Human2,2',4,4'-Tetrabromodiphenyl ether increases expressionEXP 64804642,2',4,4'-tetrabromodiphenyl ether results in increased expression of UPP1 mRNACTDPMID:31173147
UPP1Human2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of UPP1 mRNACTDPMID:16704738
UPP1Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13055666480464Tetrachlorodibenzodioxin results in increased expression of UPP1 mRNACTDPMID:33387578
UPP1Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13055666480464Tetrachlorodibenzodioxin affects the expression of UPP1 mRNACTDPMID:34747641
UPP1Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13136706480464Tetrachlorodibenzodioxin results in increased expression of UPP1 mRNACTDPMID:26290441
UPP1Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:13136706480464Tetrachlorodibenzodioxin affects the expression of UPP1 mRNACTDPMID:21570461|PMID:26377647
UPP1Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of UPP1 mRNACTDPMID:20106945|PMID:21632981
UPP1Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:13136706480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UPP1 mRNACTDPMID:17942748
UPP1Human2,4-diaminotoluene increases expressionISORGD:131367064804642,4-diaminotoluene results in increased expression of UPP1 mRNACTDPMID:20713471
UPP1Human2,4-dinitrotoluene affects expressionISORGD:130556664804642,4-dinitrotoluene affects the expression of UPP1 mRNACTDPMID:21346803
UPP1Human2,6-dimethoxyphenol multiple interactionsEXP 6480464[Sodium Chloride co-treated with pyrogallol 1,3-dimethyl ether] results in decreased expression of and affects the more ...CTDPMID:38598786
UPP1Human2-hydroxypropanoic acid decreases expressionEXP 6480464Lactic Acid results in decreased expression of UPP1 mRNACTDPMID:30851411
UPP1Human3,3',5,5'-tetrabromobisphenol A increases expressionISORGD:13136706480464tetrabromobisphenol A results in increased expression of UPP1 mRNACTDPMID:25172293

1 to 20 of 189 rows

Biological Process
1 to 19 of 19 rows

  
Object Symbol
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Reference
Notes
Source
Original Reference(s)
UPP1Humancellular response to glucose starvation  ISORGD:13055669068941 RGDPMID:18457515|REF_RGD_ID:2317094
UPP1Humancellular response to glucose starvation involved_inIEAUniProtKB:F7F0D5|UniProtKB:Q499V1|ensembl:ENSRNOP00000006765150520179 EnsemblGO_REF:0000107
UPP1HumanCMP catabolic process involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1HumandCMP catabolic process involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1HumandTMP catabolic process involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1HumandTMP catabolic process NOT|involved_inISOMGI:36991649068941 PMID:15772079UniProtPMID:15772079
UPP1HumandUMP catabolic process involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humannucleobase-containing compound metabolic process involved_inTAS 150520179 PMID:7488099PINCPMID:7488099
UPP1Humannucleoside catabolic process involved_inIEAARBA:ARBA00027612150520179 UniProtGO_REF:0000117
UPP1Humannucleoside metabolic process involved_inIEAInterPro:IPR000845|InterPro:IPR035994150520179 InterProGO_REF:0000002
UPP1Humannucleotide catabolic process involved_inIEAInterPro:IPR010059150520179 InterProGO_REF:0000002
UPP1Humanpyrimidine nucleotide metabolic process acts_upstream_of_or_withinIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1HumanUMP catabolic process involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1HumanUMP salvage involved_inIEAUniPathway:UPA00574150520179 UniProtGO_REF:0000041
UPP1HumanUMP salvage involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humanuridine catabolic process involved_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humanuridine catabolic process involved_inIBAMGI:1097668|MGI:1923904|PANTHER:PTN002885040|UniProtKB:O95045|UniProtKB:Q16831|WB:WBGene00022817150520179 GO_CentralGO_REF:0000033
UPP1Humanuridine catabolic process involved_inIDA 150520179 PMID:7488099UniProtPMID:7488099
UPP1Humanuridine metabolic process acts_upstream_of_or_withinIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
1 to 19 of 19 rows

Cellular Component

  
Object Symbol
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Term
Qualifier
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With
Reference
Notes
Source
Original Reference(s)
UPP1Humancytoplasm located_inIEAInterPro:IPR010059150520179 InterProGO_REF:0000002
UPP1Humancytosol located_inTAS 150520179 ReactomeReactome:R-HSA-74372|Reactome:R-HSA-74376
UPP1Humancytosol is_active_inIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humancytosol is_active_inIBAMGI:1097668|MGI:1923904|PANTHER:PTN000477856|UniProtKB:P0ABP8|UniProtKB:P0AE12|UniProtKB:P12758150520179 GO_CentralGO_REF:0000033
UPP1Humannucleoplasm located_inIDA 150520179 HPAGO_REF:0000052

Molecular Function
1 to 16 of 16 rows

  
Object Symbol
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Source
Original Reference(s)
UPP1Humancatalytic activity enablesIEAInterPro:IPR000845|InterPro:IPR035994150520179 InterProGO_REF:0000002
UPP1Humandeoxyuridine phosphorylase activity enablesIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humandeoxyuridine phosphorylase activity enablesIEARHEA:22824150520179 RHEAGO_REF:0000116
UPP1Humanglycosyltransferase activity enablesIEAUniProtKB-KW:KW-0328150520179 UniProtGO_REF:0000043
UPP1Humanidentical protein binding enablesIPIUniProtKB:Q16831150520179 PMID:19291308, PMID:20856879UniProtPMID:19291308|PMID:20856879
UPP1Humanpentosyltransferase activity enablesIEAARBA:ARBA00026327150520179 UniProtGO_REF:0000117
UPP1Humanpentosyltransferase activity enablesIEAInterPro:IPR018016150520179 InterProGO_REF:0000002
UPP1Humanthymidine phosphorylase activity NOT|enablesISOMGI:36991649068941 PMID:15772079UniProtPMID:15772079
UPP1Humanthymidine phosphorylase activity enablesIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humantransferase activity enablesIEAUniProtKB-KW:KW-0808150520179 UniProtGO_REF:0000043
UPP1Humanuridine phosphorylase activity enablesIDA 150520179 PMID:7488099UniProtPMID:7488099
UPP1Humanuridine phosphorylase activity enablesIBAMGI:1097668|MGI:1923904|PANTHER:PTN002885040|UniProtKB:O95045|UniProtKB:Q16831|UniProtKB:Q57VZ2|WB:WBGene00022817150520179 GO_CentralGO_REF:0000033
UPP1Humanuridine phosphorylase activity enablesIEAUniProtKB:P52624|ensembl:ENSMUSP00000020677150520179 EnsemblGO_REF:0000107
UPP1Humanuridine phosphorylase activity enablesIEARHEA:24388150520179 RHEAGO_REF:0000116
UPP1Humanuridine phosphorylase activity enablesIEAInterPro:IPR010059150520179 InterProGO_REF:0000002
UPP1Humanuridine phosphorylase activity enablesIEAEC:2.4.2.3150520179 UniProtGO_REF:0000003
1 to 16 of 16 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UPP1Humanpyrimidine metabolic pathway  IEA 6907045 KEGGhsa:00240
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
UPP1HumanPleomorphic xanthoastrocytoma  IAGPRGD:128590218554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
UPP1HumanProlonged QT interval  IAGPRGD:103954268554872ClinVar Annotator: match by term: Long QT syndromeClinVarPMID:26132555

#
Reference Title
Reference Citation
1. Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase. Choi JW, etal., J Neurotrauma. 2008 Jun;25(6):695-707.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:752472   PMID:7488099   PMID:11278417   PMID:11807789   PMID:12036313   PMID:12084455   PMID:12115385   PMID:12477932   PMID:14702039   PMID:15489334   PMID:16798057   PMID:18457437  
PMID:19291308   PMID:19714313   PMID:20856879   PMID:21873635   PMID:22632162   PMID:22898364   PMID:22939629   PMID:24453475   PMID:25754235   PMID:25963833   PMID:26344197   PMID:26496610  
PMID:27182664   PMID:28163244   PMID:28514442   PMID:28515276   PMID:28675297   PMID:29656893   PMID:31496029   PMID:32031713   PMID:32416067   PMID:32583596   PMID:32687490   PMID:32864839  
PMID:33961781   PMID:35831314   PMID:36215168   PMID:37689310   PMID:37827155   PMID:38331898   PMID:38496616   PMID:38797519  



UPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38748,088,704 - 48,108,736 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl748,088,628 - 48,108,736 (+)EnsemblGRCh38hg38GRCh38
GRCh37748,128,301 - 48,148,333 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36748,094,880 - 48,114,855 (+)NCBINCBI36Build 36hg18NCBI36
Celera748,227,538 - 48,247,515 (+)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef748,013,948 - 48,033,924 (+)NCBIHuRef
CHM1_1748,132,055 - 48,152,030 (+)NCBICHM1_1
T2T-CHM13v2.0748,250,938 - 48,270,970 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2748,168,224 - 48,188,201 (+)NCBI
Upp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39119,068,008 - 9,086,170 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl119,068,103 - 9,086,170 (+)EnsemblGRCm39 Ensembl
GRCm38119,118,008 - 9,136,170 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,118,103 - 9,136,170 (+)EnsemblGRCm38mm10GRCm38
MGSCv37119,018,011 - 9,036,173 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36119,018,106 - 9,036,167 (+)NCBIMGSCv36mm8
Celera119,551,715 - 9,569,878 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map116.13NCBI
Upp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81488,023,155 - 88,043,036 (+)NCBIGRCr8
mRatBN7.21483,809,495 - 83,829,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1483,809,960 - 83,829,462 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1488,205,103 - 88,223,414 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01489,445,021 - 89,463,332 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01485,912,157 - 85,930,471 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01489,314,234 - 89,334,060 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1489,314,176 - 89,334,276 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01489,112,302 - 89,132,102 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,651,264 - 89,669,630 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11489,669,068 - 89,688,775 (+)NCBI
Celera1482,846,265 - 82,864,631 (+)NCBICelera
Cytogenetic Map14q21NCBI
Upp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554565,365,877 - 5,385,336 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554565,365,912 - 5,385,336 (-)NCBIChiLan1.0ChiLan1.0
UPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2652,964,340 - 52,983,714 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17101,288,443 - 101,308,447 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0748,729,975 - 48,749,598 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1748,838,901 - 48,858,189 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl748,838,893 - 48,858,185 (+)Ensemblpanpan1.1panPan2
UPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.118108,215 - 120,213 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1867,812 - 89,151 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.018133,593 - 154,855 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl18133,673 - 164,752 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.118108,433 - 129,715 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.018111,361 - 132,570 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.018246,479 - 267,730 (+)NCBIUU_Cfam_GSD_1.0
Upp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118103,296,840 - 103,319,396 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647822,508,559 - 22,531,898 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647822,508,602 - 22,531,604 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,418,385 - 48,440,736 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,418,385 - 48,440,414 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12110,686,600 - 10,707,181 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2110,686,093 - 10,706,347 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606211,525,130 - 11,545,495 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Upp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247405,517,387 - 5,531,594 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in UPP1
11 total Variants

1 to 10 of 29 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p12.3(chr7:47843159-48156272)x3 copy number gain See cases [RCV000053438] Chr7:47843159..48156272 [GRCh38]
Chr7:47882757..48195869 [GRCh37]
Chr7:47849282..48162394 [NCBI36]
Chr7:7p12.3		 uncertain significance
GRCh38/hg38 7p14.3-q11.21(chr7:33328312-62377476)x3 copy number gain See cases [RCV000053532] Chr7:33328312..62377476 [GRCh38]
Chr7:33367924..61831899 [GRCh37]
Chr7:33334449..61469334 [NCBI36]
Chr7:7p14.3-q11.21		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7p13-12.1(chr7:44571949-53699760)x1 copy number loss See cases [RCV000134973] Chr7:44571949..53699760 [GRCh38]
Chr7:44611548..53767453 [GRCh37]
Chr7:44578073..53734947 [NCBI36]
Chr7:7p13-12.1		 pathogenic
GRCh38/hg38 7p14.1-11.2(chr7:40534157-56107122)x1 copy number loss See cases [RCV000136092] Chr7:40534157..56107122 [GRCh38]
Chr7:40573756..56174815 [GRCh37]
Chr7:40540281..56142309 [NCBI36]
Chr7:7p14.1-11.2		 pathogenic
GRCh38/hg38 7p14.1-12.1(chr7:40020598-50543500)x1 copy number loss See cases [RCV000136904] Chr7:40020598..50543500 [GRCh38]
Chr7:40060197..50611198 [GRCh37]
Chr7:40026722..50578692 [NCBI36]
Chr7:7p14.1-12.1		 pathogenic
GRCh38/hg38 7p14.1-12.3(chr7:37303478-48660738)x1 copy number loss See cases [RCV000137139] Chr7:37303478..48660738 [GRCh38]
Chr7:37343082..48700334 [GRCh37]
Chr7:37309607..48670880 [NCBI36]
Chr7:7p14.1-12.3		 pathogenic
GRCh38/hg38 7p12.3(chr7:48012022-48129375)x3 copy number gain See cases [RCV000141289] Chr7:48012022..48129375 [GRCh38]
Chr7:48051619..48168972 [GRCh37]
Chr7:48018144..48135497 [NCBI36]
Chr7:7p12.3		 uncertain significance
NM_003364.4(UPP1):c.280C>T (p.Arg94Cys) single nucleotide variant Long QT syndrome [RCV000190211] Chr7:48101941 [GRCh38]
Chr7:48141538 [GRCh37]
Chr7:7p12.3		 likely benign
1 to 10 of 29 rows

Predicted Target Of
Summary Value
Count of predictions:2652
Count of miRNA genes:829
Interacting mature miRNAs:961
Transcripts:ENST00000331803, ENST00000341253, ENST00000395560, ENST00000395564, ENST00000416681, ENST00000417464, ENST00000421046, ENST00000429491, ENST00000432131, ENST00000436673, ENST00000444999, ENST00000457596, ENST00000482015, ENST00000495446
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 10 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1558711BP56_HBlood pressure QTL 56 (human)2.240.000002Blood pressuresystolic73634937162349371Human
407048160GWAS697136_Huridine measurement QTL GWAS697136 (human)6e-08uridine measurement74809512248095123Human
597280270GWAS1376344_H5-methyluridine (ribothymidine) measurement QTL GWAS1376344 (human)2e-205-methyluridine (ribothymidine) measurement74809198348091984Human
597280544GWAS1376618_Huridine measurement QTL GWAS1376618 (human)5e-21uridine measurement74808977448089775Human
1559132SAPOB3_HSerum apolipoprotein B level QTL 3 (human)20.4Apolipoprotein levelapolipoprotein B73289107458891074Human
597515808GWAS1611882_Huridine measurement QTL GWAS1611882 (human)3e-10uridine measurement74808906048089061Human
597436545GWAS1532619_Huracil measurement QTL GWAS1532619 (human)1e-10uracil measurement74810259748102598Human
2302781MAMTS16_HMammary tumor susceptibility QTL 16 (human)0.033Mammary tumor susceptibility73634937162349371Human
2289453BW297_HBody weight QTL 297 (human)3.83Body weightbody mass index72334946449349464Human
597530226GWAS1626300_H5-methyluridine (ribothymidine) measurement QTL GWAS1626300 (human)3e-165-methyluridine (ribothymidine) measurement74808896148088962Human

1 to 10 of 10 rows
WI-11994  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37748,147,875 - 48,148,002UniSTSGRCh37
Build 36748,114,400 - 48,114,527RGDNCBI36
Celera748,247,060 - 48,247,187RGD
Cytogenetic Map7p12.3UniSTS
HuRef748,033,469 - 48,033,596UniSTS
CRA_TCAGchr7v2748,187,746 - 48,187,873UniSTS
GeneMap99-GB4 RH Map7200.51UniSTS
Whitehead-RH Map7173.6UniSTS
UPP1_7899  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37748,147,925 - 48,148,486UniSTSGRCh37
Build 36748,114,450 - 48,115,011RGDNCBI36
Celera748,247,110 - 48,247,671RGD
HuRef748,033,519 - 48,034,080UniSTS
CRA_TCAGchr7v2748,187,796 - 48,188,357UniSTS
G35510  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q21UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map1q42.13UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map9q13-q21UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map7p12.3UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map20q11.2-q13.2UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic MapXp22UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map2p25-p24UniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map4q21.3UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map1p35UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic MapXp11UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map12q22UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map9p12UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map14q13.2UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map6pter-q22.33UniSTS
Cytogenetic Map14q32.2UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map2q32.1UniSTS
Cytogenetic Map9q21.33UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map11q14.2-q21UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map3q28UniSTS
Cytogenetic Map9p21.3UniSTS
Cytogenetic Map7p15.1UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map5q31-q32UniSTS
Cytogenetic Map18p11.2UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map12p13.33UniSTS
Cytogenetic Map18p11.22-p11.21UniSTS
Cytogenetic Map5q34-q35UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map12q23.3UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p36.2UniSTS
Cytogenetic Map12q14.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map11q13.3UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map16p13.2UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map10q26.1UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic MapXp22.32UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map1q23.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map15q13.3UniSTS
Cytogenetic MapXp21.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map6pter-p12.1UniSTS
Cytogenetic Map6p24.3UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map17pUniSTS
Cytogenetic Map3p26UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map20q13.33UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2438 2788 2253 4970 1726 2350 6 623 1945 465 2269 7299 6465 53 3730 1 852 1744 1616 175 1


1 to 30 of 45 rows
RefSeq Transcripts NG_051802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001287426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001287428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001287429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001287430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_109837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005249838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011515512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011515513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011515514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011515515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC069279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC007348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC047030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 45 rows

Ensembl Acc Id: ENST00000331803   ⟹   ENSP00000330032
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,088,644 - 48,108,733 (+)Ensembl
Ensembl Acc Id: ENST00000395560   ⟹   ENSP00000378927
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,265 - 48,108,419 (+)Ensembl
Ensembl Acc Id: ENST00000395564   ⟹   ENSP00000378931
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,265 - 48,108,736 (+)Ensembl
Ensembl Acc Id: ENST00000416681   ⟹   ENSP00000405209
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,088,628 - 48,103,407 (+)Ensembl
Ensembl Acc Id: ENST00000417464   ⟹   ENSP00000413611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,376 - 48,108,419 (+)Ensembl
Ensembl Acc Id: ENST00000421046   ⟹   ENSP00000414963
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,227 - 48,103,991 (+)Ensembl
Ensembl Acc Id: ENST00000432131   ⟹   ENSP00000387607
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,088,661 - 48,099,714 (+)Ensembl
Ensembl Acc Id: ENST00000436673   ⟹   ENSP00000390118
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,265 - 48,103,413 (+)Ensembl
Ensembl Acc Id: ENST00000444999   ⟹   ENSP00000396820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,282 - 48,107,082 (+)Ensembl
Ensembl Acc Id: ENST00000457596   ⟹   ENSP00000408899
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,088,727 - 48,108,302 (+)Ensembl
Ensembl Acc Id: ENST00000482015
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,089,344 - 48,108,419 (+)Ensembl
Ensembl Acc Id: ENST00000495446
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl748,104,646 - 48,108,415 (+)Ensembl
RefSeq Acc Id: NM_001287426   ⟹   NP_001274355
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,088,704 - 48,108,736 (+)NCBI
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,131,900 - 48,152,030 (+)NCBI
T2T-CHM13v2.0748,250,938 - 48,270,970 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001287428   ⟹   NP_001274357
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,088,704 - 48,108,736 (+)NCBI
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,131,900 - 48,152,030 (+)NCBI
T2T-CHM13v2.0748,250,938 - 48,270,970 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001287429   ⟹   NP_001274358
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,265 - 48,108,736 (+)NCBI
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,132,437 - 48,152,030 (+)NCBI
T2T-CHM13v2.0748,251,499 - 48,270,970 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001287430   ⟹   NP_001274359
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,254 - 48,108,733 (+)NCBI
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,132,551 - 48,152,030 (+)NCBI
T2T-CHM13v2.0748,251,488 - 48,270,967 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001362774   ⟹   NP_001349703
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,088,704 - 48,108,736 (+)NCBI
T2T-CHM13v2.0748,250,938 - 48,270,970 (+)NCBI
Sequence:
RefSeq Acc Id: NM_003364   ⟹   NP_003355
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,265 - 48,108,736 (+)NCBI
GRCh37748,128,355 - 48,148,330 (+)NCBI
Build 36748,095,271 - 48,114,855 (+)NCBI Archive
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,132,509 - 48,152,030 (+)NCBI
T2T-CHM13v2.0748,251,499 - 48,270,970 (+)NCBI
CRA_TCAGchr7v2748,168,224 - 48,188,201 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NR_109837
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,254 - 48,108,733 (+)NCBI
HuRef748,013,793 - 48,033,924 (+)NCBI
CHM1_1748,132,551 - 48,152,030 (+)NCBI
T2T-CHM13v2.0748,251,488 - 48,270,967 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011515512   ⟹   XP_011513814
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,088,704 - 48,108,736 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011515513   ⟹   XP_011513815
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,212 - 48,108,736 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011515514   ⟹   XP_011513816
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,212 - 48,108,736 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047420797   ⟹   XP_047276753
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,212 - 48,108,736 (+)NCBI
RefSeq Acc Id: XM_047420798   ⟹   XP_047276754
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,212 - 48,104,267 (+)NCBI
RefSeq Acc Id: XM_047420799   ⟹   XP_047276755
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,212 - 48,104,267 (+)NCBI
RefSeq Acc Id: XM_054358929   ⟹   XP_054214904
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0748,250,938 - 48,270,970 (+)NCBI
RefSeq Acc Id: XM_054358930   ⟹   XP_054214905
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0748,251,446 - 48,270,970 (+)NCBI
RefSeq Acc Id: XM_054358931   ⟹   XP_054214906
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0748,251,446 - 48,270,970 (+)NCBI
RefSeq Acc Id: XM_054358932   ⟹   XP_054214907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0748,251,446 - 48,270,970 (+)NCBI
RefSeq Acc Id: XM_054358933   ⟹   XP_054214908
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0748,251,446 - 48,268,436 (+)NCBI
RefSeq Acc Id: XM_054358934   ⟹   XP_054214909
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0748,251,446 - 48,268,436 (+)NCBI
1 to 30 of 40 rows
Protein RefSeqs NP_001274355 (Get FASTA)   NCBI Sequence Viewer  
  NP_001274357 (Get FASTA)   NCBI Sequence Viewer  
  NP_001274358 (Get FASTA)   NCBI Sequence Viewer  
  NP_001274359 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349703 (Get FASTA)   NCBI Sequence Viewer  
  NP_003355 (Get FASTA)   NCBI Sequence Viewer  
  XP_011513814 (Get FASTA)   NCBI Sequence Viewer  
  XP_011513815 (Get FASTA)   NCBI Sequence Viewer  
  XP_011513816 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276753 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276754 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276755 (Get FASTA)   NCBI Sequence Viewer  
  XP_054214904 (Get FASTA)   NCBI Sequence Viewer  
  XP_054214905 (Get FASTA)   NCBI Sequence Viewer  
  XP_054214906 (Get FASTA)   NCBI Sequence Viewer  
  XP_054214907 (Get FASTA)   NCBI Sequence Viewer  
  XP_054214908 (Get FASTA)   NCBI Sequence Viewer  
  XP_054214909 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH01405 (Get FASTA)   NCBI Sequence Viewer  
  AAH07348 (Get FASTA)   NCBI Sequence Viewer  
  AAH47030 (Get FASTA)   NCBI Sequence Viewer  
  AAH53592 (Get FASTA)   NCBI Sequence Viewer  
  AAP35345 (Get FASTA)   NCBI Sequence Viewer  
  BAG60192 (Get FASTA)   NCBI Sequence Viewer  
  CAA62369 (Get FASTA)   NCBI Sequence Viewer  
  CAA62370 (Get FASTA)   NCBI Sequence Viewer  
  EAW60993 (Get FASTA)   NCBI Sequence Viewer  
  EAW60994 (Get FASTA)   NCBI Sequence Viewer  
  EAW60995 (Get FASTA)   NCBI Sequence Viewer  
  EAW60996 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 40 rows
1 to 5 of 28 rows
1 to 5 of 28 rows
RefSeq Acc Id: NP_003355   ⟸   NM_003364
- Peptide Label: isoform a
- UniProtKB: D3DVM4 (UniProtKB/Swiss-Prot),   Q15362 (UniProtKB/Swiss-Prot),   Q16831 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001274355   ⟸   NM_001287426
- Peptide Label: isoform a
- UniProtKB: D3DVM4 (UniProtKB/Swiss-Prot),   Q15362 (UniProtKB/Swiss-Prot),   Q16831 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001274357   ⟸   NM_001287428
- Peptide Label: isoform b
- UniProtKB: Q86Y75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001274358   ⟸   NM_001287429
- Peptide Label: isoform b
- UniProtKB: Q86Y75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001274359   ⟸   NM_001287430
- Peptide Label: isoform b
- UniProtKB: Q86Y75 (UniProtKB/TrEMBL)
- Sequence:
Nucleoside phosphorylase

Name Modeler Protein Id AA Range Protein Structure
AF-Q16831-F1-model_v2 AlphaFold Q16831 1-310 view protein structure

RGD ID:7210573
Promoter ID:EPDNEW_H11032
Type:initiation region
Name:UPP1_2
Description:uridine phosphorylase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11033  EPDNEW_H11034  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,088,708 - 48,088,768EPDNEW
RGD ID:7210575
Promoter ID:EPDNEW_H11033
Type:initiation region
Name:UPP1_1
Description:uridine phosphorylase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11032  EPDNEW_H11034  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,265 - 48,089,325EPDNEW
RGD ID:7210577
Promoter ID:EPDNEW_H11034
Type:initiation region
Name:UPP1_3
Description:uridine phosphorylase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11032  EPDNEW_H11033  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38748,089,369 - 48,089,429EPDNEW
RGD ID:6806384
Promoter ID:HG_KWN:57363
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000331803,   NM_003364,   NM_181597,   OTTHUMT00000341750,   OTTHUMT00000341755,   OTTHUMT00000341757,   OTTHUMT00000341758,   OTTHUMT00000341759,   OTTHUMT00000341760,   UC003TOM.1,   UC003TON.1,   UC003TOO.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36748,094,821 - 48,095,497 (+)MPROMDB
RGD ID:6853040
Promoter ID:EP74341
Type:initiation region
Name:HS_UP
Description:Uridine phosphorylase.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 36748,095,372 - 48,095,432EPD


1 to 40 of 40 rows
Database
Acc Id
Source(s)
COSMIC UPP1 COSMIC
Ensembl Genes ENSG00000183696 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000331803 ENTREZGENE
  ENST00000331803.8 UniProtKB/Swiss-Prot
  ENST00000395560.7 UniProtKB/Swiss-Prot
  ENST00000395564 ENTREZGENE
  ENST00000395564.9 UniProtKB/Swiss-Prot
  ENST00000416681 ENTREZGENE
  ENST00000417464.6 UniProtKB/Swiss-Prot
  ENST00000436673 ENTREZGENE
  ENST00000457596.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1580 UniProtKB/Swiss-Prot
GTEx ENSG00000183696 GTEx
HGNC ID HGNC:12576 ENTREZGENE
Human Proteome Map UPP1 Human Proteome Map
InterPro Nucleoside_phosphorylase_CS UniProtKB/Swiss-Prot
  Nucleoside_phosphorylase_d UniProtKB/Swiss-Prot
  Nucleoside_phosphorylase_sf UniProtKB/Swiss-Prot
  Uridine_phosphorylase_euk UniProtKB/Swiss-Prot
KEGG Report hsa:7378 UniProtKB/Swiss-Prot
NCBI Gene 7378 ENTREZGENE
OMIM 191730 OMIM
PANTHER URIDINE PHOSPHORYLASE UniProtKB/Swiss-Prot
  URIDINE PHOSPHORYLASE 1 UniProtKB/Swiss-Prot
Pfam PNP_UDP_1 UniProtKB/Swiss-Prot
PharmGKB PA365 PharmGKB, RGD
PROSITE PNP_UDP_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53167 UniProtKB/Swiss-Prot
UniProt B4DND0 ENTREZGENE, UniProtKB/TrEMBL
  C9J486_HUMAN UniProtKB/TrEMBL
  C9JIP2 ENTREZGENE, UniProtKB/TrEMBL
  C9K0J2_HUMAN UniProtKB/TrEMBL
  D3DVM4 ENTREZGENE
  F8WD51_HUMAN UniProtKB/TrEMBL
  Q15362 ENTREZGENE
  Q16831 ENTREZGENE
  Q86Y75 ENTREZGENE, UniProtKB/TrEMBL
  UPP1_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary D3DVM4 UniProtKB/Swiss-Prot
  Q15362 UniProtKB/Swiss-Prot
1 to 40 of 40 rows