Sfmbt1 (Scm-like with four mbt domains 1) - Rat Genome Database
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Gene: Sfmbt1 (Scm-like with four mbt domains 1) Rattus norvegicus
Analyze
Symbol: Sfmbt1
Name: Scm-like with four mbt domains 1
RGD ID: 61999
Description: Predicted to have histone binding activity. Predicted to be involved in negative regulation of muscle organ development and negative regulation of transcription, DNA-templated. Predicted to localize to nucleoplasm. Orthologous to human SFMBT1 (Scm like with four mbt domains 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC680626; MGC93349; scm-like with four MBT domains protein 1; Scm-related gene containing four mbt domains; Sfmbt; similar to farnesyl diphosphate synthetase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2165,889,046 - 6,009,860 (+)NCBI
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0166,775,648 - 6,896,155 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0166,705,856 - 6,825,699 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,124,155 - 6,241,008 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1166,185,489 - 6,241,002 (+)NCBI
Celera169,184,923 - 9,236,952 (-)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO,ISS)

Molecular Function

References

Additional References at PubMed
PMID:15489334   PMID:16751776   PMID:17599839   PMID:23349461   PMID:23592795  


Genomics

Comparative Map Data
Sfmbt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2165,889,046 - 6,009,860 (+)NCBI
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0166,775,648 - 6,896,155 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0166,705,856 - 6,825,699 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,124,155 - 6,241,008 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1166,185,489 - 6,241,002 (+)NCBI
Celera169,184,923 - 9,236,952 (-)NCBICelera
Cytogenetic Map16p16NCBI
SFMBT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl352,903,572 - 53,046,750 (-)EnsemblGRCh38hg38GRCh38
GRCh38352,899,209 - 53,046,655 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37352,937,588 - 53,080,089 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,913,667 - 53,055,110 (-)NCBINCBI36hg18NCBI36
Build 34352,913,667 - 53,055,110NCBI
Celera352,916,400 - 53,047,177 (-)NCBI
Cytogenetic Map3p21.1NCBI
HuRef352,999,200 - 53,129,628 (-)NCBIHuRef
CHM1_1352,889,772 - 53,031,734 (-)NCBICHM1_1
Sfmbt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,436,806 - 30,544,678 (+)NCBIGRCm39mm39
GRCm39 Ensembl1430,436,806 - 30,544,678 (+)Ensembl
GRCm381430,714,849 - 30,822,721 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,714,849 - 30,822,721 (+)EnsemblGRCm38mm10GRCm38
MGSCv371431,528,035 - 31,635,907 (+)NCBIGRCm37mm9NCBIm37
MGSCv361429,595,009 - 29,646,972 (+)NCBImm8
Celera1426,972,255 - 27,079,725 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.99NCBI
Sfmbt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,856,054 - 2,915,517 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,850,149 - 3,014,859 (-)NCBIChiLan1.0ChiLan1.0
SFMBT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1354,071,144 - 54,215,061 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,071,144 - 54,138,538 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0352,841,693 - 52,991,613 (-)NCBIMhudiblu_PPA_v0panPan3
SFMBT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2036,921,566 - 36,972,675 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12036,853,108 - 36,978,306 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Sfmbt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364733,650,096 - 3,784,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFMBT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,025,767 - 35,180,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11335,020,627 - 35,181,074 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,213,183 - 38,314,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFMBT1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,285,362 - 14,439,624 (-)NCBI
ChlSab1.1 Ensembl2214,290,494 - 14,438,192 (-)Ensembl
Sfmbt1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,160,661 - 4,328,058 (+)NCBI

Position Markers
RH130554  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0166,894,924 - 6,895,106NCBIRnor6.0
Rnor_5.0166,820,954 - 6,821,136UniSTSRnor5.0
RGSC_v3.4166,240,631 - 6,240,813UniSTSRGSC3.4
Celera169,185,118 - 9,185,300UniSTS
RH 3.4 Map1634.2UniSTS
Cytogenetic Map16p16UniSTS
AW531515  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0166,776,782 - 6,776,947NCBIRnor6.0
Rnor_5.0166,706,990 - 6,707,155UniSTSRnor5.0
RGSC_v3.4166,121,964 - 6,122,129UniSTSRGSC3.4
Celera169,299,445 - 9,299,610UniSTS
RH 3.4 Map1641.7UniSTS
Cytogenetic Map16p16UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16110660736Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16124228366Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16127556253Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16127556253Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16127556253Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16131816439Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16133160624Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16134465490Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16141240937Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16141240937Rat
631561Hcuc2Hepatic copper content QTL 22.8hepatic copper amount (VT:0003065)liver total copper weight (CMO:0001507)16141240957Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)1624459345244593Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)16109005486162972Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16134074146340741Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)16155018749247447Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)16155018763210301Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16155018763210301Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)16155018763210301Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)16155018763210301Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16172829746728297Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16329668817464293Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16413635523105837Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16413635545905331Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16501380218360147Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16501380245905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16501380245905331Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16501380245905331Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16501380250013802Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16501380250169318Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16501380252144919Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16501380264012784Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16509870419398181Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:323
Count of miRNA genes:202
Interacting mature miRNAs:236
Transcripts:ENSRNOT00000022865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 8 56 41 19 41 74 35 41 11
Low 35 1 8 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000022865   ⟹   ENSRNOP00000022865
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084713   ⟹   ENSRNOP00000074701
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl166,806,170 - 6,895,007 (+)Ensembl
RefSeq Acc Id: NM_031647   ⟹   NP_113835
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,891,524 - 6,005,481 (+)NCBI
Rnor_6.0166,779,281 - 6,895,301 (+)NCBI
Rnor_5.0166,705,856 - 6,825,699 (+)NCBI
RGSC_v3.4166,124,155 - 6,241,008 (+)RGD
Celera169,184,923 - 9,236,952 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252656   ⟹   XP_006252718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,918,129 - 6,009,860 (+)NCBI
Rnor_6.0166,806,169 - 6,896,155 (+)NCBI
Rnor_5.0166,705,856 - 6,825,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006252657   ⟹   XP_006252719
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,918,129 - 6,009,860 (+)NCBI
Rnor_6.0166,806,169 - 6,896,155 (+)NCBI
Rnor_5.0166,705,856 - 6,825,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006252658   ⟹   XP_006252720
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,889,046 - 6,009,860 (+)NCBI
Rnor_6.0166,775,648 - 6,896,155 (+)NCBI
Rnor_5.0166,705,856 - 6,825,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771003   ⟹   XP_008769225
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,779,164 - 6,896,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771004   ⟹   XP_008769226
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,806,169 - 6,896,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771005   ⟹   XP_008769227
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,806,169 - 6,896,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008771006   ⟹   XP_008769228
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,918,129 - 6,009,860 (+)NCBI
Rnor_6.0166,806,169 - 6,896,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600239   ⟹   XP_017455728
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,802,393 - 6,896,155 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094800   ⟹   XP_038950728
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,891,213 - 6,009,860 (+)NCBI
RefSeq Acc Id: XM_039094801   ⟹   XP_038950729
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,918,129 - 6,009,860 (+)NCBI
RefSeq Acc Id: XM_039094802   ⟹   XP_038950730
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2165,891,213 - 6,009,860 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_113835   ⟸   NM_031647
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006252720   ⟸   XM_006252658
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006252719   ⟸   XM_006252657
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006252718   ⟸   XM_006252656
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008769225   ⟸   XM_008771003
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008769227   ⟸   XM_008771005
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008769228   ⟸   XM_008771006
- Peptide Label: isoform X1
- UniProtKB: Q9JMD2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008769226   ⟸   XM_008771004
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017455728   ⟸   XM_017600239
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000074701   ⟸   ENSRNOT00000084713
RefSeq Acc Id: ENSRNOP00000022865   ⟸   ENSRNOT00000022865
RefSeq Acc Id: XP_038950728   ⟸   XM_039094800
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950730   ⟸   XM_039094802
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950729   ⟸   XM_039094801
- Peptide Label: isoform X1
Protein Domains
SAM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699911
Promoter ID:EPDNEW_R10435
Type:initiation region
Name:Sfmbt1_1
Description:Scm-like with four mbt domains 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0166,779,262 - 6,779,322EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61999 AgrOrtholog
Ensembl Genes ENSRNOG00000016645 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000022865 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000074701 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022865 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000084713 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot
  1.20.1380.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7132495 IMAGE-MGC_LOAD
InterPro Mbt UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
  SAM/pointed_sf UniProtKB/Swiss-Prot
  Scm-like-4MBT1/2_SAM UniProtKB/Swiss-Prot
  SLED UniProtKB/Swiss-Prot
  SLED_sf UniProtKB/Swiss-Prot
KEGG Report rno:58967 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93349 IMAGE-MGC_LOAD
NCBI Gene 58967 ENTREZGENE
Pfam MBT UniProtKB/Swiss-Prot
  SAM_1 UniProtKB/Swiss-Prot
  SLED UniProtKB/Swiss-Prot
PhenoGen Sfmbt1 PhenoGen
PROSITE MBT UniProtKB/Swiss-Prot
SMART MBT UniProtKB/Swiss-Prot
  SAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot
TIGR TC219843
UniProt Q9JMD2 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q66HN3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Sfmbt1  Scm-like with four mbt domains 1  LOC680626  similar to farnesyl diphosphate synthetase  Data Merged 737654 PROVISIONAL
2006-11-19 LOC680626  similar to farnesyl diphosphate synthetase      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Sfmbt1  Scm-like with four mbt domains 1  Sfmbt  Scm-related gene containing four mbt domains   Symbol and Name updated 1299863 APPROVED
2002-06-10 Sfmbt  Scm-related gene containing four mbt domains       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains contains the SPM domain and mbt repeats 61748