UPP1 (uridine phosphorylase 1) - Rat Genome Database
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Gene: UPP1 (uridine phosphorylase 1) Sus scrofa
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Symbol: UPP1
Name: uridine phosphorylase 1
RGD ID: 14114960
Description: ENCODES a protein that exhibits deoxyuridine phosphorylase activity (ortholog); thymidine phosphorylase activity (ortholog); uridine phosphorylase activity (ortholog); INVOLVED IN cellular response to glucose starvation (ortholog); CMP catabolic process (ortholog); dCMP catabolic process (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); long QT syndrome (ortholog); middle cerebral artery infarction (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,418,385 - 48,440,736 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,418,385 - 48,440,414 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
nucleoplasm  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
UPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,418,385 - 48,440,736 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,418,385 - 48,440,414 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl748,088,628 - 48,108,736 (+)EnsemblGRCh38hg38GRCh38
GRCh38748,088,308 - 48,108,736 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37748,128,301 - 48,148,333 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37748,128,355 - 48,148,330 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36748,094,880 - 48,114,855 (+)NCBINCBI36hg18NCBI36
Celera748,227,538 - 48,247,515 (+)NCBI
Cytogenetic Map7p12.3NCBI
HuRef748,013,948 - 48,033,924 (+)NCBIHuRef
CHM1_1748,131,900 - 48,152,030 (+)NCBICHM1_1
CRA_TCAGchr7v2748,168,224 - 48,188,201 (+)NCBI
Upp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39119,068,008 - 9,086,170 (+)NCBIGRCm39mm39
GRCm38119,118,008 - 9,136,170 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl119,118,103 - 9,136,170 (+)EnsemblGRCm38mm10GRCm38
MGSCv37119,018,011 - 9,036,173 (+)NCBIGRCm37mm9NCBIm37
MGSCv36119,018,106 - 9,036,167 (+)NCBImm8
Celera119,551,715 - 9,569,878 (+)NCBICelera
Cytogenetic Map11A1NCBI
Upp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21483,809,495 - 83,829,299 (+)NCBI
Rnor_6.0 Ensembl1489,314,176 - 89,334,276 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01489,314,234 - 89,334,060 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01489,112,302 - 89,132,102 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41489,651,264 - 89,669,630 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11489,669,068 - 89,688,775 (+)NCBI
Celera1482,846,265 - 82,864,631 (+)NCBICelera
Cytogenetic Map14q21NCBI
Upp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554565,365,877 - 5,385,336 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554565,365,912 - 5,385,336 (-)NCBIChiLan1.0ChiLan1.0
UPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1748,838,901 - 48,858,189 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl748,838,893 - 48,858,185 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0748,729,975 - 48,749,598 (+)NCBIMhudiblu_PPA_v0panPan3
UPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.118108,215 - 120,213 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Upp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647822,508,602 - 22,531,604 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UPP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12110,686,600 - 10,707,181 (-)NCBI
ChlSab1.1 Ensembl2110,686,093 - 10,706,347 (-)Ensembl
Upp1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247405,517,387 - 5,531,594 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system reproductive system respiratory system
High
Medium 1 1 3
Low 8 2 3 4 5
Below cutoff 2 9

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000024494   ⟹   ENSSSCP00000027238
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1848,418,385 - 48,426,629 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000052968   ⟹   ENSSSCP00000037244
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1848,418,385 - 48,440,460 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000065553   ⟹   ENSSSCP00000048025
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1848,418,396 - 48,440,736 (-)Ensembl
RefSeq Acc Id: XM_021078788   ⟹   XP_020934447
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11848,418,385 - 48,440,334 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021078790   ⟹   XP_020934449
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11848,418,385 - 48,440,414 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002340288
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11848,418,389 - 48,440,327 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020934447 (Get FASTA)   NCBI Sequence Viewer  
  XP_020934449 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020934449   ⟸   XM_021078790
- Sequence:
RefSeq Acc Id: XP_020934447   ⟸   XM_021078788
- Sequence:
RefSeq Acc Id: ENSSSCP00000027238   ⟸   ENSSSCT00000024494
RefSeq Acc Id: ENSSSCP00000048025   ⟸   ENSSSCT00000065553
RefSeq Acc Id: ENSSSCP00000037244   ⟸   ENSSSCT00000052968
Protein Domains
PNP_UDP_1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000030388 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070014319 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000027238 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000037244 UniProtKB/TrEMBL
  ENSSSCP00000048025 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070023363 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024494 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000052968 UniProtKB/TrEMBL
  ENSSSCT00000065553 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070028065 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1580 UniProtKB/TrEMBL
InterPro Nucleoside_phosphorylase_CS UniProtKB/TrEMBL
  Nucleoside_phosphorylase_d UniProtKB/TrEMBL
  Nucleoside_phosphorylase_sf UniProtKB/TrEMBL
  Uridine_phosphorylase_euk UniProtKB/TrEMBL
NCBI Gene UPP1 ENTREZGENE
Pfam PNP_UDP_1 UniProtKB/TrEMBL
PROSITE PNP_UDP_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53167 UniProtKB/TrEMBL
TIGRFAMs euk_UDPppase UniProtKB/TrEMBL
UniProt A0A287A0H1_PIG UniProtKB/TrEMBL
  A0A480S6M1_PIG UniProtKB/TrEMBL
  A0A4X1U3H6_PIG UniProtKB/TrEMBL
  I3LSZ5_PIG UniProtKB/TrEMBL
VGNC ID VGNC:94725 ENTREZGENE