IRF5 (interferon regulatory factor 5) - Rat Genome Database

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Gene: IRF5 (interferon regulatory factor 5) Homo sapiens
Analyze
Symbol: IRF5
Name: interferon regulatory factor 5
RGD ID: 1321354
HGNC Page HGNC:6120
Description: Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; identical protein binding activity; and protein kinase binding activity. Involved in several processes, including cellular response to virus; positive regulation of macromolecule biosynthetic process; and response to peptidoglycan. Located in cytoplasm and nucleus. Implicated in herpes simplex; inflammatory bowel disease 14; multiple sclerosis; rheumatoid arthritis; and systemic lupus erythematosus. Biomarker of hepatitis C; liver cirrhosis; metabolic dysfunction-associated steatohepatitis; and pneumonia.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: IRF-5; SLEB10
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: IRF5P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387128,937,032 - 128,950,038 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7128,937,457 - 128,950,038 (+)EnsemblGRCh38hg38GRCh38
GRCh377128,577,086 - 128,590,092 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367128,365,230 - 128,377,325 (+)NCBINCBI36Build 36hg18NCBI36
Build 347128,172,221 - 128,184,037NCBI
Celera7123,374,509 - 123,386,585 (+)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7122,939,186 - 122,951,277 (+)NCBIHuRef
CHM1_17128,511,266 - 128,523,397 (+)NCBICHM1_1
T2T-CHM13v2.07130,249,958 - 130,262,927 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
actinomycin D  (EXP)
alpha-phellandrene  (EXP)
amitrole  (ISO)
amphotericin B  (EXP)
antirheumatic drug  (EXP)
Bardoxolone methyl  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buta-1,3-diene  (ISO)
camptothecin  (EXP)
carbon nanotube  (ISO)
CGP 52608  (EXP)
cisplatin  (EXP)
clofibrate  (ISO)
copper(II) sulfate  (EXP)
corn oil  (ISO)
crocidolite asbestos  (ISO)
curcumin  (EXP)
dexamethasone  (EXP)
dichloroacetic acid  (ISO)
dichloromethane  (ISO)
dimethylarsinic acid  (EXP)
diquat  (ISO)
endosulfan  (ISO)
ethyl methanesulfonate  (EXP)
fenvalerate  (ISO)
hydrogen peroxide  (EXP)
indometacin  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (EXP,ISO)
menadione  (EXP)
metam  (ISO)
metformin  (EXP)
methimazole  (ISO)
methotrexate  (EXP)
methyl methanesulfonate  (EXP)
nickel atom  (EXP)
nickel sulfate  (EXP)
Nutlin-3  (EXP)
ozone  (ISO)
paclitaxel  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
protein kinase inhibitor  (EXP)
resiquimod  (EXP)
rimonabant  (ISO)
sorafenib  (EXP)
tamoxifen  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
valproic acid  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromatin  (ISA)
cytoplasm  (IDA,IEA)
cytosol  (TAS)
nucleoplasm  (TAS)
nucleus  (IBA,IDA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abdominal distention  (IAGP)
Abnormal bowel sounds  (IAGP)
Abnormal circulating lipid concentration  (IAGP)
Abnormal intrahepatic bile duct morphology  (IAGP)
Abnormal pigmentation of the oral mucosa  (IAGP)
Abnormality of salivation  (IAGP)
Abnormality of skin pigmentation  (IAGP)
Abnormality of the skin  (IAGP)
Abnormality of the thyroid gland  (IAGP)
Alopecia  (IAGP)
Anorexia  (IAGP)
Anti-complement component C1q antibody positivity  (IAGP)
Anti-dsDNA antibody positivity  (IAGP)
Anti-La/SS-B antibody positivity  (IAGP)
Anti-nucleoporin 62 antibody positivity  (IAGP)
Anti-phosphatidic acid antibody positivity  (IAGP)
Anti-ribosome Po antibody positivity  (IAGP)
Anti-Ro52/TRIM21 antibody positivity  (IAGP)
Anti-Sm antibody positivity  (IAGP)
Anti-titin antibody positivity  (IAGP)
Anti-U1 ribonucleoprotein antibody positivity  (IAGP)
Antimitochondrial antibody positivity  (IAGP)
Antineutrophil antibody positivity  (IAGP)
Antinuclear antibody positivity  (IAGP)
Arthralgia  (IAGP)
Arthritis  (IAGP)
Ascites  (IAGP)
Autoimmunity  (IAGP)
Biliary cirrhosis  (IAGP)
Carious teeth  (IAGP)
Celiac disease  (IAGP)
Cheilitis  (IAGP)
Chorea  (IAGP)
Cirrhosis  (IAGP)
Congestive heart failure  (IAGP)
Conjugated hyperbilirubinemia  (IAGP)
Cutaneous photosensitivity  (IAGP)
Decreased circulating complement C3 concentration  (IAGP)
Decreased circulating complement C4 concentration  (IAGP)
Depression  (IAGP)
Dermatographic urticaria  (IAGP)
Discoid lupus rash  (IAGP)
Dyspareunia  (IAGP)
Dysphagia  (IAGP)
Dyspnea  (IAGP)
Elevated circulating alkaline phosphatase concentration  (IAGP)
Elevated gamma-glutamyltransferase level  (IAGP)
Esophageal varix  (IAGP)
Excessive daytime somnolence  (IAGP)
Fatigue  (IAGP)
Fever  (IAGP)
Flexion contracture  (IAGP)
Foot joint contracture  (IAGP)
Gastroesophageal reflux  (IAGP)
Gastrointestinal inflammation  (IAGP)
Hematuria  (IAGP)
Hemolytic anemia  (IAGP)
Hepatic encephalopathy  (IAGP)
Hepatic failure  (IAGP)
Hepatic fibrosis  (IAGP)
Hepatitis  (IAGP)
Hepatocellular carcinoma  (IAGP)
Hepatomegaly  (IAGP)
Hypercholesterolemia  (IAGP)
Hyperpigmentation of the skin  (IAGP)
Hypertension  (IAGP)
Hypertensive crisis  (IAGP)
Hypoalbuminemia  (IAGP)
Hypopigmented skin patches  (IAGP)
Increased circulating IgA concentration  (IAGP)
Increased circulating IgM level  (IAGP)
Jaundice  (IAGP)
Joint contracture of the hand  (IAGP)
Leukopenia  (IAGP)
Lupus nephritis  (IAGP)
Lymphadenopathy  (IAGP)
Malabsorption  (IAGP)
Malaise  (IAGP)
Malar rash  (IAGP)
Mucosal telangiectasiae  (IAGP)
Muscle weakness  (IAGP)
Narrow foramen obturatorium  (IAGP)
Nausea and vomiting  (IAGP)
Oliguria  (IAGP)
Onychomycosis  (IAGP)
Oral ulcer  (IAGP)
Orthostatic hypotension  (IAGP)
Osteolysis  (IAGP)
Osteoporosis  (IAGP)
Pleomorphic xanthoastrocytoma  (IAGP)
Polyarticular arthritis  (IAGP)
Portal hypertension  (IAGP)
Proteinuria  (IAGP)
Pruritus  (IAGP)
Pulmonary arterial hypertension  (IAGP)
Pulmonary fibrosis  (IAGP)
Pulmonary infiltrates  (IAGP)
Pyuria  (IAGP)
Raynaud phenomenon  (IAGP)
Recurrent fungal infections  (IAGP)
Renal insufficiency  (IAGP)
Retinopathy  (IAGP)
Rheumatoid arthritis  (IAGP)
Seizure  (IAGP)
Serositis  (IAGP)
Skin ulcer  (IAGP)
Sleep abnormality  (IAGP)
Splenomegaly  (IAGP)
Steatorrhea  (IAGP)
Telangiectasia of the skin  (IAGP)
Thrombocytopenia  (IAGP)
Weight loss  (IAGP)
Xanthelasma  (IAGP)
Xerostomia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans. Alzaid F, etal., JCI Insight. 2016 Dec 8;1(20):e88689. doi: 10.1172/jci.insight.88689.
2. Interferon regulatory factor 5 is a potential target of autoimmune response triggered by Epstein-barr virus and Mycobacterium avium subsp. paratuberculosis in rheumatoid arthritis: investigating a mechanism of molecular mimicry. Bo M, etal., Clin Exp Rheumatol. 2018 May-Jun;36(3):376-381. Epub 2018 Jan 15.
3. Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mouse model of antigen-induced arthritis. Bo M, etal., J Transl Autoimmun. 2020 Mar 17;3:100048. doi: 10.1016/j.jtauto.2020.100048. eCollection 2020.
4. Rheumatoid arthritis patient antibodies highly recognize IL-2 in the immune response pathway involving IRF5 and EBV antigens. Bo M, etal., Sci Rep. 2018 Jan 29;8(1):1789. doi: 10.1038/s41598-018-19957-z.
5. MicroRNA-302a suppresses influenza A virus-stimulated interferon regulatory factor-5 expression and cytokine storm induction. Chen X, etal., J Biol Chem. 2017 Dec 29;292(52):21291-21303. doi: 10.1074/jbc.M117.805937. Epub 2017 Oct 18.
6. Human interferon regulatory factor 5 homologous epitopes of Epstein-Barr virus and Mycobacterium avium subsp. paratuberculosis induce a specific humoral and cellular immune response in multiple sclerosis patients. Cossu D, etal., Mult Scler. 2015 Jul;21(8):984-95. doi: 10.1177/1352458514557304. Epub 2014 Nov 12.
7. IRF-5 Promotes Cell Death in CD4 T Cells during Chronic Infection. Fabié A, etal., Cell Rep. 2018 Jul 31;24(5):1163-1175. doi: 10.1016/j.celrep.2018.06.107.
8. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
9. Glucocorticoid modulates high-mobility group box 1 expression and Toll-like receptor activation in obstructive jaundice. Huang YH, etal., J Surg Res. 2011 Sep;170(1):e47-55. doi: 10.1016/j.jss.2011.05.033. Epub 2011 Jun 15.
10. Sedum sarmentosum Bunge extract alleviates inflammation and kidney injury via inhibition of M1-macrophage polarization. Lu H, etal., Phytomedicine. 2019 Sep;62:152976. doi: 10.1016/j.phymed.2019.152976. Epub 2019 May 31.
11. IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice. Mai LT, etal., Front Immunol. 2020 Jan 21;10:3071. doi: 10.3389/fimmu.2019.03071. eCollection 2019.
12. Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats. Mapplebeck JCS, etal., Pain. 2018 Sep;159(9):1752-1763. doi: 10.1097/j.pain.0000000000001265.
13. The protective effect of interfering TLR9-IRF5 signaling pathway on the development of CVB3-induced myocarditis. Nie S, etal., Clin Immunol. 2019 Oct;207:24-35. doi: 10.1016/j.clim.2019.07.002. Epub 2019 Jul 4.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System. Proenca-Modena JL, etal., J Virol. 2015 Oct 14;90(1):189-205. doi: 10.1128/JVI.02276-15.
17. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
18. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
19. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
20. Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection. Thackray LB, etal., J Virol. 2014 Oct;88(19):11007-21. doi: 10.1128/JVI.01545-14. Epub 2014 Jul 16.
21. Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat. Urdzíková LM, etal., Int J Mol Sci. 2014 Jun 25;15(7):11275-93. doi: 10.3390/ijms150711275.
22. Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection. Vandenbroeck K, etal., Genes Immun. 2011 Jan;12(1):40-5. doi: 10.1038/gene.2010.46. Epub 2010 Sep 23.
23. Expression Levels of Interferon Regulatory Factor 5 (IRF5) and Related Inflammatory Cytokines Associated with Severity, Prognosis, and Causative Pathogen in Patients with Community-Acquired Pneumonia. Wang X, etal., Med Sci Monit. 2018 May 30;24:3620-3630. doi: 10.12659/MSM.910756.
24. An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathway. Xiao Y, etal., Mol Med. 2017 Sep;23:166-176. doi: 10.2119/molmed.2016.00243. Epub 2017 Jun 14.
25. Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
26. Differences in IP‑10, TLR4 and IRF5/3 between SVR and non‑SVR HCV‑1 patients treated with PEG‑IFN and ribavirin. Zhang M, etal., Mol Med Rep. 2017 Apr;15(4):2318-2324. doi: 10.3892/mmr.2017.6229. Epub 2017 Feb 22.
Additional References at PubMed
PMID:9865487   PMID:11303025   PMID:11846976   PMID:11997525   PMID:12138184   PMID:12477932   PMID:12600985   PMID:12690205   PMID:14559832   PMID:15308637   PMID:15489334   PMID:15556946  
PMID:15657875   PMID:15665823   PMID:15695821   PMID:15805103   PMID:16642019   PMID:17121613   PMID:17133578   PMID:17158136   PMID:17166181   PMID:17189288   PMID:17389033   PMID:17393452  
PMID:17412832   PMID:17476532   PMID:17557928   PMID:17568788   PMID:17599733   PMID:17609264   PMID:17703412   PMID:17881657   PMID:18050197   PMID:18063667   PMID:18200047   PMID:18204098  
PMID:18204446   PMID:18260169   PMID:18285424   PMID:18288123   PMID:18311811   PMID:18323517   PMID:18332133   PMID:18408250   PMID:18438842   PMID:18505922   PMID:18579578   PMID:18668568  
PMID:18752149   PMID:18824541   PMID:18836453   PMID:18843782   PMID:18843785   PMID:19019891   PMID:19028697   PMID:19043711   PMID:19092842   PMID:19116937   PMID:19129183   PMID:19228650  
PMID:19258923   PMID:19274049   PMID:19430534   PMID:19479858   PMID:19565491   PMID:19567624   PMID:19644876   PMID:19644887   PMID:19758313   PMID:19778284   PMID:19786094   PMID:19816589  
PMID:19838193   PMID:19851296   PMID:19854706   PMID:19877059   PMID:19913121   PMID:19918036   PMID:20015215   PMID:20049410   PMID:20080916   PMID:20090783   PMID:20112383   PMID:20127100  
PMID:20131273   PMID:20137629   PMID:20197570   PMID:20198315   PMID:20211142   PMID:20231204   PMID:20237317   PMID:20351107   PMID:20383147   PMID:20439292   PMID:20453440   PMID:20453842  
PMID:20479942   PMID:20503287   PMID:20588308   PMID:20616560   PMID:20628086   PMID:20639879   PMID:20639880   PMID:20695768   PMID:20797713   PMID:20848568   PMID:20861858   PMID:20881011  
PMID:20935208   PMID:20962850   PMID:20980283   PMID:21040166   PMID:21133648   PMID:21156761   PMID:21239750   PMID:21297633   PMID:21399635   PMID:21408207   PMID:21454650   PMID:21471993  
PMID:21627826   PMID:21750679   PMID:21779181   PMID:21807777   PMID:21834935   PMID:21873635   PMID:21898142   PMID:21903422   PMID:21968701   PMID:21988832   PMID:22025054   PMID:22053985  
PMID:22088620   PMID:22179739   PMID:22194884   PMID:22257839   PMID:22412986   PMID:22440820   PMID:22500098   PMID:22507190   PMID:22544929   PMID:22674082   PMID:22730365   PMID:22816737  
PMID:22909381   PMID:22995936   PMID:23053960   PMID:23073787   PMID:23128233   PMID:23154183   PMID:23236436   PMID:23273568   PMID:23288367   PMID:23302156   PMID:23332764   PMID:23349905  
PMID:23372721   PMID:23392701   PMID:23616277   PMID:23740937   PMID:23801380   PMID:23883595   PMID:23941291   PMID:23971939   PMID:23985571   PMID:23990993   PMID:24014567   PMID:24116155  
PMID:24350899   PMID:24445143   PMID:24532789   PMID:24582590   PMID:24697319   PMID:24697591   PMID:24871463   PMID:24928322   PMID:24943672   PMID:25011482   PMID:25036352   PMID:25084355  
PMID:25159141   PMID:25205108   PMID:25263394   PMID:25284481   PMID:25288773   PMID:25326418   PMID:25326420   PMID:25337792   PMID:25533286   PMID:25557482   PMID:25564941   PMID:25565375  
PMID:25572744   PMID:25649192   PMID:26004104   PMID:26112714   PMID:26233721   PMID:26279299   PMID:26294277   PMID:26519527   PMID:26613957   PMID:26638075   PMID:26712637   PMID:27092776  
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PMID:35701499   PMID:35748872   PMID:35810492   PMID:35967345   PMID:36245280   PMID:36529029   PMID:36782048   PMID:36869052   PMID:37254791   PMID:37594849   PMID:38141865   PMID:38175709  
PMID:38451436   PMID:38745265   PMID:38969706   PMID:39271190  


Genomics

Comparative Map Data
IRF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387128,937,032 - 128,950,038 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7128,937,457 - 128,950,038 (+)EnsemblGRCh38hg38GRCh38
GRCh377128,577,086 - 128,590,092 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367128,365,230 - 128,377,325 (+)NCBINCBI36Build 36hg18NCBI36
Build 347128,172,221 - 128,184,037NCBI
Celera7123,374,509 - 123,386,585 (+)NCBICelera
Cytogenetic Map7q32.1NCBI
HuRef7122,939,186 - 122,951,277 (+)NCBIHuRef
CHM1_17128,511,266 - 128,523,397 (+)NCBICHM1_1
T2T-CHM13v2.07130,249,958 - 130,262,927 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)NCBI
Irf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,526,129 - 29,541,874 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl629,526,624 - 29,541,870 (+)EnsemblGRCm39 Ensembl
GRCm38629,526,130 - 29,541,869 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,526,625 - 29,541,871 (+)EnsemblGRCm38mm10GRCm38
MGSCv37629,476,733 - 29,487,319 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36629,476,743 - 29,487,329 (+)NCBIMGSCv36mm8
Celera629,535,579 - 29,546,163 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.36NCBI
Irf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8459,092,914 - 59,104,596 (+)NCBIGRCr8
mRatBN7.2458,127,577 - 58,140,665 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl458,127,640 - 58,139,267 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx463,111,395 - 63,122,649 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0459,027,547 - 59,038,814 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0457,429,439 - 57,440,694 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0456,804,477 - 56,816,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl456,805,132 - 56,820,543 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0456,571,823 - 56,583,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,407,560 - 56,418,694 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1456,666,980 - 56,677,876 (+)NCBI
Celera453,236,000 - 53,247,024 (+)NCBICelera
Cytogenetic Map4q22NCBI
IRF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26165,742,532 - 165,754,167 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1717,752,862 - 17,764,413 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07120,889,752 - 120,902,096 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17133,415,170 - 133,426,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7133,415,170 - 133,426,356 (+)Ensemblpanpan1.1panPan2
IRF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,724,168 - 7,734,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,724,780 - 7,742,795 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,411,116 - 7,421,966 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,490,116 - 7,500,966 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,489,132 - 7,500,059 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,695,157 - 7,706,007 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,437,183 - 7,448,035 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0147,582,360 - 7,592,901 (-)NCBIUU_Cfam_GSD_1.0
Irf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511826,005,766 - 26,016,934 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365796,138,281 - 6,145,205 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365796,138,372 - 6,149,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1819,678,687 - 19,691,243 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11819,678,377 - 19,691,154 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21820,748,271 - 20,760,087 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IRF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12197,536,803 - 97,549,576 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2197,537,790 - 97,549,945 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660425,852,040 - 5,864,687 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247837,260,005 - 7,274,433 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247837,267,680 - 7,275,918 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IRF5
52 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001347928.2(IRF5):c.-12+596GCGGG[4] microsatellite Inflammatory bowel disease 14, susceptibility to [RCV000003562]|Systemic lupus erythematosus, susceptibility to, 10 [RCV000003563] Chr7:128937860..128937861 [GRCh38]
Chr7:128577914..128577915 [GRCh37]
Chr7:7q32.1		 risk factor
NM_001098629.3(IRF5):c.-12+198= single nucleotide variant Rheumatoid arthritis [RCV000003565]|Systemic lupus erythematosus, susceptibility to, 10 [RCV000003564] Chr7:128938247 [GRCh38]
Chr7:128578301 [GRCh37]
Chr7:7q32.1		 pathogenic|risk factor|association
NM_001098629.3(IRF5):c.*555G>A single nucleotide variant Systemic lupus erythematosus, susceptibility to, 10 [RCV000003566] Chr7:128949373 [GRCh38]
Chr7:128949373..128949374 [GRCh38]
Chr7:128589427 [GRCh37]
Chr7:128589427..128589428 [GRCh37]
Chr7:7q32.1		 risk factor
NM_001098629.3(IRF5):c.*128T>C single nucleotide variant Systemic lupus erythematosus, association with susceptibility to, 10 [RCV000003567] Chr7:128948946 [GRCh38]
Chr7:128948946..128948947 [GRCh38]
Chr7:128589000 [GRCh37]
Chr7:128589000..128589001 [GRCh37]
Chr7:7q32.1		 risk factor
GRCh38/hg38 7q32.1-33(chr7:128747478-134018250)x3 copy number gain See cases [RCV000051072] Chr7:128747478..134018250 [GRCh38]
Chr7:128387532..133703003 [GRCh37]
Chr7:128174768..133353543 [NCBI36]
Chr7:7q32.1-33		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q31.33-32.3(chr7:126859732-132750936)x1 copy number loss See cases [RCV000054171] Chr7:126859732..132750936 [GRCh38]
Chr7:126499786..132435696 [GRCh37]
Chr7:126287022..132086236 [NCBI36]
Chr7:7q31.33-32.3		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 copy number gain See cases [RCV000136717] Chr7:97419852..158923762 [GRCh38]
Chr7:97049164..158716453 [GRCh37]
Chr7:96887100..158409214 [NCBI36]
Chr7:7q21.3-36.3		 pathogenic
GRCh38/hg38 7q31.2-33(chr7:117326805-134790689)x1 copy number loss See cases [RCV000138226] Chr7:117326805..134790689 [GRCh38]
Chr7:116966859..134475440 [GRCh37]
Chr7:116754095..134125980 [NCBI36]
Chr7:7q31.2-33		 pathogenic
GRCh38/hg38 7q31.32-36.3(chr7:121863759-159335865)x3 copy number gain See cases [RCV000138847] Chr7:121863759..159335865 [GRCh38]
Chr7:121503813..159128555 [GRCh37]
Chr7:121291049..158821316 [NCBI36]
Chr7:7q31.32-36.3		 pathogenic
GRCh38/hg38 7q31.2-36.3(chr7:115459015-159325817)x3 copy number gain See cases [RCV000141413] Chr7:115459015..159325817 [GRCh38]
Chr7:115099069..159118507 [GRCh37]
Chr7:114886305..158811268 [NCBI36]
Chr7:7q31.2-36.3		 pathogenic
GRCh38/hg38 7q32.1(chr7:127817826-129237503)x3 copy number gain See cases [RCV000142106] Chr7:127817826..129237503 [GRCh38]
Chr7:127457880..128877344 [GRCh37]
Chr7:127245116..128664580 [NCBI36]
Chr7:7q32.1		 likely benign|uncertain significance
GRCh38/hg38 7q31.33-33(chr7:124170657-134163594)x1 copy number loss See cases [RCV000142552] Chr7:124170657..134163594 [GRCh38]
Chr7:123810711..133848346 [GRCh37]
Chr7:123597947..133498886 [NCBI36]
Chr7:7q31.33-33		 pathogenic
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q22.1-36.3(chr7:98969247-159119707)x3 copy number gain See cases [RCV000447709] Chr7:98969247..159119707 [GRCh37]
Chr7:7q22.1-36.3		 pathogenic
GRCh37/hg19 7q32.1-34(chr7:127295698-139524358)x1 copy number loss See cases [RCV000447722] Chr7:127295698..139524358 [GRCh37]
Chr7:7q32.1-34		 pathogenic
GRCh37/hg19 7q32.1-36.3(chr7:128276078-159119707)x3 copy number gain See cases [RCV000447956] Chr7:128276078..159119707 [GRCh37]
Chr7:7q32.1-36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_001098629.3(IRF5):c.1265G>A (p.Arg422His) single nucleotide variant not specified [RCV004313648] Chr7:128948294 [GRCh38]
Chr7:128588348 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.494C>T (p.Ser165Phe) single nucleotide variant not specified [RCV004310172] Chr7:128947242 [GRCh38]
Chr7:128587296 [GRCh37]
Chr7:7q32.1		 uncertain significance
GRCh37/hg19 7q22.1-36.3(chr7:98693388-159119707)x3 copy number gain not provided [RCV000682911] Chr7:98693388..159119707 [GRCh37]
Chr7:7q22.1-36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q32.1(chr7:128542838-128817136)x3 copy number gain not provided [RCV000747045] Chr7:128542838..128817136 [GRCh37]
Chr7:7q32.1		 benign
NM_001098629.3(IRF5):c.249G>A (p.Pro83=) single nucleotide variant not provided [RCV000905998] Chr7:128945898 [GRCh38]
Chr7:128585952 [GRCh37]
Chr7:7q32.1		 benign
NM_001098629.3(IRF5):c.1504G>A (p.Gly502Ser) single nucleotide variant not provided [RCV000970179] Chr7:128948777 [GRCh38]
Chr7:128588831 [GRCh37]
Chr7:7q32.1		 likely benign
NM_001098629.3(IRF5):c.572_601del (p.Arg191_Leu200del) deletion not provided [RCV000947069] Chr7:128947298..128947327 [GRCh38]
Chr7:128587352..128587381 [GRCh37]
Chr7:7q32.1		 benign
NM_001098629.3(IRF5):c.303C>T (p.Arg101=) single nucleotide variant not provided [RCV000927133] Chr7:128945952 [GRCh38]
Chr7:128586006 [GRCh37]
Chr7:7q32.1		 likely benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_001098629.3(IRF5):c.447G>A (p.Glu149=) single nucleotide variant not provided [RCV000881012] Chr7:128946562 [GRCh38]
Chr7:128586616 [GRCh37]
Chr7:7q32.1		 benign
NM_001098629.3(IRF5):c.729G>A (p.Leu243=) single nucleotide variant not provided [RCV000895015] Chr7:128947477 [GRCh38]
Chr7:128587531 [GRCh37]
Chr7:7q32.1		 likely benign
GRCh37/hg19 7q32.1-36.3(chr7:128312450-159119220) copy number gain not provided [RCV000767558] Chr7:128312450..159119220 [GRCh37]
Chr7:7q32.1-36.3		 pathogenic
NM_001098629.3(IRF5):c.576G>A (p.Pro192=) single nucleotide variant not provided [RCV000893678] Chr7:128947324 [GRCh38]
Chr7:128587378 [GRCh37]
Chr7:7q32.1		 benign
GRCh37/hg19 7q31.32-32.2(chr7:121480906-129389003)x1 copy number loss not provided [RCV000847911] Chr7:121480906..129389003 [GRCh37]
Chr7:7q31.32-32.2		 pathogenic
NM_001098629.3(IRF5):c.226G>A (p.Glu76Lys) single nucleotide variant not specified [RCV004300540] Chr7:128945875 [GRCh38]
Chr7:128585929 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1050T>G (p.Leu350=) single nucleotide variant not provided [RCV000953256] Chr7:128947991 [GRCh38]
Chr7:128588045 [GRCh37]
Chr7:7q32.1		 benign|likely benign
NM_001098629.3(IRF5):c.354C>T (p.Tyr118=) single nucleotide variant not provided [RCV000890511] Chr7:128946003 [GRCh38]
Chr7:128586057 [GRCh37]
Chr7:7q32.1		 likely benign
NM_001098629.3(IRF5):c.-12+1563G>A single nucleotide variant not provided [RCV001669876] Chr7:128939612 [GRCh38]
Chr7:128579666 [GRCh37]
Chr7:7q32.1		 benign
GRCh37/hg19 7q31.1-36.3(chr7:109251060-159119707)x3 copy number gain not provided [RCV001005994] Chr7:109251060..159119707 [GRCh37]
Chr7:7q31.1-36.3		 pathogenic
Single allele complex Ring chromosome 7 [RCV002280646] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q31.33-33(chr7:124103982-134693590) copy number loss not specified [RCV002053726] Chr7:124103982..134693590 [GRCh37]
Chr7:7q31.33-33		 pathogenic
GRCh37/hg19 7q32.1-34(chr7:127295698-139524358) copy number loss not specified [RCV002053727] Chr7:127295698..139524358 [GRCh37]
Chr7:7q32.1-34		 pathogenic
GRCh37/hg19 7q22.3-32.1(chr7:106984287-128949489) copy number gain not specified [RCV002053715] Chr7:106984287..128949489 [GRCh37]
Chr7:7q22.3-32.1		 pathogenic
GRCh37/hg19 7q31.33-33(chr7:123967475-132729981) copy number loss not specified [RCV002053723] Chr7:123967475..132729981 [GRCh37]
Chr7:7q31.33-33		 pathogenic
NC_000007.13:g.(?_128470692)_(128694824_?)dup duplication Autosomal dominant limb-girdle muscular dystrophy type 1F [RCV001879723]|Myofibrillar myopathy 5 [RCV001902472] Chr7:128470692..128694824 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1373G>A (p.Arg458Gln) single nucleotide variant not provided [RCV002223670]|not specified [RCV004047226] Chr7:128948646 [GRCh38]
Chr7:128588700 [GRCh37]
Chr7:7q32.1		 uncertain significance
GRCh37/hg19 7p22.3-q36.3(chr7:56604613-96692931)x1 copy number loss See cases [RCV002287832] Chr7:56604613..96692931 [GRCh37]
Chr7:7p22.3-q36.3		 uncertain significance
NM_001098629.3(IRF5):c.1021C>A (p.Leu341Ile) single nucleotide variant not specified [RCV004130482] Chr7:128947962 [GRCh38]
Chr7:128588016 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.897G>C (p.Gln299His) single nucleotide variant not specified [RCV004100757] Chr7:128947838 [GRCh38]
Chr7:128587892 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.605C>T (p.Pro202Leu) single nucleotide variant not specified [RCV004093112] Chr7:128947353 [GRCh38]
Chr7:128587407 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.863G>A (p.Cys288Tyr) single nucleotide variant not specified [RCV004129739] Chr7:128947804 [GRCh38]
Chr7:128587858 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1047C>A (p.Asp349Glu) single nucleotide variant not specified [RCV004146604] Chr7:128947988 [GRCh38]
Chr7:128588042 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.421G>A (p.Gly141Arg) single nucleotide variant not specified [RCV004085244] Chr7:128946536 [GRCh38]
Chr7:128586590 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1090G>A (p.Gly364Arg) single nucleotide variant not specified [RCV004117239] Chr7:128948031 [GRCh38]
Chr7:128588085 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.16C>G (p.Pro6Ala) single nucleotide variant not specified [RCV004197439] Chr7:128942097 [GRCh38]
Chr7:128582151 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1109A>G (p.His370Arg) single nucleotide variant not specified [RCV004123198] Chr7:128948050 [GRCh38]
Chr7:128588104 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.44T>G (p.Val15Gly) single nucleotide variant not specified [RCV004231378] Chr7:128942125 [GRCh38]
Chr7:128582179 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1113C>G (p.Asp371Glu) single nucleotide variant not specified [RCV004228897] Chr7:128948054 [GRCh38]
Chr7:128588108 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1113C>A (p.Asp371Glu) single nucleotide variant not specified [RCV004178383] Chr7:128948054 [GRCh38]
Chr7:128588108 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.940C>T (p.Arg314Cys) single nucleotide variant not specified [RCV004203902] Chr7:128947881 [GRCh38]
Chr7:128587935 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.541T>A (p.Trp181Arg) single nucleotide variant not specified [RCV004092095] Chr7:128947289 [GRCh38]
Chr7:128587343 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.824G>A (p.Arg275Gln) single nucleotide variant not specified [RCV004096901] Chr7:128947765 [GRCh38]
Chr7:128587819 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1264C>T (p.Arg422Cys) single nucleotide variant not specified [RCV004253896] Chr7:128948293 [GRCh38]
Chr7:128588347 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.1456C>T (p.Arg486Trp) single nucleotide variant Systemic lupus erythematosus, susceptibility to, 10 [RCV003140643] Chr7:128948729 [GRCh38]
Chr7:128588783 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.650C>A (p.Ala217Asp) single nucleotide variant not specified [RCV004323973] Chr7:128947398 [GRCh38]
Chr7:128587452 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.650C>T (p.Ala217Val) single nucleotide variant not specified [RCV004332552] Chr7:128947398 [GRCh38]
Chr7:128587452 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.623C>T (p.Pro208Leu) single nucleotide variant not specified [RCV004340116] Chr7:128947371 [GRCh38]
Chr7:128587425 [GRCh37]
Chr7:7q32.1		 uncertain significance
GRCh37/hg19 7q31.33-32.2(chr7:127076892-129405807)x1 copy number loss not provided [RCV003482986] Chr7:127076892..129405807 [GRCh37]
Chr7:7q31.33-32.2		 pathogenic
GRCh37/hg19 7q31.31-33(chr7:120582003-137699953)x1 copy number loss not specified [RCV003986721] Chr7:120582003..137699953 [GRCh37]
Chr7:7q31.31-33		 pathogenic
NM_001098629.3(IRF5):c.195+10G>A single nucleotide variant IRF5-related disorder [RCV003947292] Chr7:128942286 [GRCh38]
Chr7:128582340 [GRCh37]
Chr7:7q32.1		 likely benign
NM_001098629.3(IRF5):c.413T>A (p.Phe138Tyr) single nucleotide variant not specified [RCV004403265] Chr7:128946528 [GRCh38]
Chr7:128586582 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.535G>A (p.Val179Ile) single nucleotide variant not specified [RCV004403266] Chr7:128947283 [GRCh38]
Chr7:128587337 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.575C>T (p.Pro192Leu) single nucleotide variant not specified [RCV004403267] Chr7:128947323 [GRCh38]
Chr7:128587377 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.716T>C (p.Leu239Pro) single nucleotide variant not specified [RCV004403268] Chr7:128947464 [GRCh38]
Chr7:128587518 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.722C>T (p.Ala241Val) single nucleotide variant not specified [RCV004403269] Chr7:128947470 [GRCh38]
Chr7:128587524 [GRCh37]
Chr7:7q32.1		 uncertain significance
NM_001098629.3(IRF5):c.829C>G (p.Pro277Ala) single nucleotide variant not specified [RCV004403271] Chr7:128947770 [GRCh38]
Chr7:128587824 [GRCh37]
Chr7:7q32.1		 uncertain significance
NC_000007.13:g.(?_128470692)_(128694824_?)del deletion Myofibrillar myopathy 5 [RCV004583555] Chr7:128470692..128694824 [GRCh37]
Chr7:7q32.1		 pathogenic
NC_000007.13:g.(?_128388409)_(128694824_?)del deletion Autosomal dominant limb-girdle muscular dystrophy type 1F [RCV004583504] Chr7:128388409..128694824 [GRCh37]
Chr7:7q32.1		 uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR146Ahsa-miR-146a-3pMirecordsexternal_infoNANA19333922

Predicted Target Of
Summary Value
Count of predictions:6953
Count of miRNA genes:1116
Interacting mature miRNAs:1418
Transcripts:ENST00000249375, ENST00000357234, ENST00000402030, ENST00000461416, ENST00000464557, ENST00000465603, ENST00000467002, ENST00000473745, ENST00000473787, ENST00000477535, ENST00000479582, ENST00000488569, ENST00000489702
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406895040GWAS544016_Hprimary biliary cirrhosis QTL GWAS544016 (human)4e-09primary biliary cirrhosis7128939148128939149Human
407220805GWAS869781_Hlymphocyte count QTL GWAS869781 (human)2e-10lymphocyte countblood lymphocyte count (CMO:0000031)7128938247128938248Human
406907649GWAS556625_Hsystemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus QTL GWAS556625 (human)7e-17systemic scleroderma, rheumatoid arthritis, myositis, systemic lupus erythematosus7128949579128949580Human
406914690GWAS563666_Hsystemic lupus erythematosus QTL GWAS563666 (human)5e-45systemic lupus erythematosus7128938253128938254Human
406989764GWAS638740_HSjogren syndrome QTL GWAS638740 (human)3e-14Sjogren syndrome7128939612128939613Human
407261441GWAS910417_Hplatelet count QTL GWAS910417 (human)1e-14platelet quantity (VT:0003179)platelet count (CMO:0000029)7128937250128937251Human
407308352GWAS957328_Hpulse pressure measurement QTL GWAS957328 (human)2e-10pulse pressure measurementpulse pressure (CMO:0000292)7128941781128941782Human
406886280GWAS535256_Hsystemic lupus erythematosus QTL GWAS535256 (human)6e-24systemic lupus erythematosus7128948946128948947Human
407296911GWAS945887_Hsystemic lupus erythematosus QTL GWAS945887 (human)1e-60systemic lupus erythematosus7128945562128945563Human
407319309GWAS968285_Hrheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement QTL GWAS968285 (human)1e-11rheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement7128938247128938248Human
407373763GWAS1022739_Hsystemic lupus erythematosus QTL GWAS1022739 (human)1e-99systemic lupus erythematosus7128945562128945563Human
407291274GWAS940250_Hrheumatoid arthritis QTL GWAS940250 (human)5e-13rheumatoid arthritis7128938247128938248Human
406964561GWAS613537_Hrheumatoid arthritis, COVID-19 QTL GWAS613537 (human)1e-09rheumatoid arthritis, COVID-197128939148128939149Human
407379992GWAS1028968_HBehcet's syndrome QTL GWAS1028968 (human)0.000006Behcet's syndrome7128946981128946982Human
407056850GWAS705826_Heosinophil count QTL GWAS705826 (human)5e-21eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)7128939612128939613Human
407121111GWAS770087_Hrheumatoid arthritis QTL GWAS770087 (human)0.0000003rheumatoid arthritis7128940626128940627Human
407313556GWAS962532_Heosinophil count QTL GWAS962532 (human)2e-11eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)7128939612128939613Human
407216275GWAS865251_Hplatelet count QTL GWAS865251 (human)1e-15platelet quantity (VT:0003179)platelet count (CMO:0000029)7128937250128937251Human
406987866GWAS636842_Hinflammatory bowel disease QTL GWAS636842 (human)3e-08inflammatory bowel disease7128937860128937866Human
407055259GWAS704235_Hbody height QTL GWAS704235 (human)2e-08body height (VT:0001253)body height (CMO:0000106)7128938247128938248Human
407074334GWAS723310_Hrheumatoid arthritis QTL GWAS723310 (human)4e-12rheumatoid arthritis7128939988128939989Human
407058780GWAS707756_Heosinophil count QTL GWAS707756 (human)3e-19eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)7128939612128939613Human
407122529GWAS771505_Hhypothyroidism QTL GWAS771505 (human)2e-09hypothyroidism7128939148128939149Human
406989796GWAS638772_HSjogren syndrome QTL GWAS638772 (human)7e-11Sjogren syndrome7128939612128939613Human
407362158GWAS1011134_Hclear cell renal carcinoma QTL GWAS1011134 (human)1e-13clear cell renal carcinoma7128940626128940627Human
407366829GWAS1015805_Hsystemic lupus erythematosus QTL GWAS1015805 (human)2e-45systemic lupus erythematosus7128945562128945563Human
406943274GWAS592250_Heosinophil count QTL GWAS592250 (human)5e-12eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)7128939148128939149Human
407013801GWAS662777_Hrheumatoid arthritis QTL GWAS662777 (human)7e-10rheumatoid arthritis7128940626128940627Human
407076200GWAS725176_Hrheumatoid arthritis QTL GWAS725176 (human)3e-14rheumatoid arthritis7128939988128939989Human
407013996GWAS662972_Hrheumatoid arthritis QTL GWAS662972 (human)5e-10rheumatoid arthritis7128940626128940627Human
407110059GWAS759035_Hautoimmune disease QTL GWAS759035 (human)7e-17autoimmune disease7128939148128939149Human
407255740GWAS904716_Hinflammatory bowel disease QTL GWAS904716 (human)7e-09inflammatory bowel disease7128940626128940627Human
407359933GWAS1008909_Hrenal carcinoma QTL GWAS1008909 (human)8e-18renal carcinoma7128940626128940627Human
406895551GWAS544527_HSjogren syndrome QTL GWAS544527 (human)0.000003Sjogren syndrome7128949373128949374Human

Markers in Region
GDB:4585333  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377128,589,096 - 128,589,195UniSTSGRCh37
Build 367128,376,332 - 128,376,431RGDNCBI36
Celera7123,385,592 - 123,385,691RGD
Cytogenetic Map7q32UniSTS
HuRef7122,950,284 - 122,950,383UniSTS
CRA_TCAGchr7v27127,972,839 - 127,972,938UniSTS
STS-U51127  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377128,588,868 - 128,589,113UniSTSGRCh37
Build 367128,376,104 - 128,376,349RGDNCBI36
Celera7123,385,364 - 123,385,609RGD
Cytogenetic Map7q32UniSTS
HuRef7122,950,056 - 122,950,301UniSTS
CRA_TCAGchr7v27127,972,611 - 127,972,856UniSTS
GeneMap99-GB4 RH Map7590.81UniSTS
NCBI RH Map71183.9UniSTS
SHGC-63648  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377128,589,289 - 128,589,384UniSTSGRCh37
Build 367128,376,525 - 128,376,620RGDNCBI36
Celera7123,385,785 - 123,385,880RGD
Cytogenetic Map7q32UniSTS
HuRef7122,950,477 - 122,950,572UniSTS
CRA_TCAGchr7v27127,973,032 - 127,973,127UniSTS
TNG Radiation Hybrid Map757797.0UniSTS
IRF5_452  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377128,588,702 - 128,589,467UniSTSGRCh37
Build 367128,375,938 - 128,376,703RGDNCBI36
Celera7123,385,198 - 123,385,963RGD
HuRef7122,949,890 - 122,950,655UniSTS
CRA_TCAGchr7v27127,972,445 - 127,973,210UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2433 2788 2253 4964 1721 2343 4 623 1949 464 2262 7298 6467 43 3733 1 852 1738 1610 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001098627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001098629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001098630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001242452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001347928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_032643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006715974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB290013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC025594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL713733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY504946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY504947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY519978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY693665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY693666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY693667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY693668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY693669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU540632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU950658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA427676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA444548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC427600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ277633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ277634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ995491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ995492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ995493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ995494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ995495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ995496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF064718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU258895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU258896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU258897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU258898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ950681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ950682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ950683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ950684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ950685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF459647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP843545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT583929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000249375   ⟹   ENSP00000249375
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,938,217 - 128,950,030 (+)Ensembl
Ensembl Acc Id: ENST00000357234   ⟹   ENSP00000349770
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,927 - 128,950,038 (+)Ensembl
Ensembl Acc Id: ENST00000402030   ⟹   ENSP00000385352
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,989 - 128,950,035 (+)Ensembl
Ensembl Acc Id: ENST00000461416
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,981 - 128,947,745 (+)Ensembl
Ensembl Acc Id: ENST00000464557   ⟹   ENSP00000419056
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,972 - 128,945,967 (+)Ensembl
Ensembl Acc Id: ENST00000465603   ⟹   ENSP00000418534
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,940,838 - 128,949,388 (+)Ensembl
Ensembl Acc Id: ENST00000467002   ⟹   ENSP00000417454
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,940,206 - 128,942,259 (+)Ensembl
Ensembl Acc Id: ENST00000473745   ⟹   ENSP00000419149
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,940,672 - 128,949,388 (+)Ensembl
Ensembl Acc Id: ENST00000473787   ⟹   ENSP00000420274
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,991 - 128,946,556 (+)Ensembl
Ensembl Acc Id: ENST00000477535   ⟹   ENSP00000419950
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,940 - 128,948,832 (+)Ensembl
Ensembl Acc Id: ENST00000479582   ⟹   ENSP00000417770
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,962 - 128,946,540 (+)Ensembl
Ensembl Acc Id: ENST00000488569
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,937 - 128,946,942 (+)Ensembl
Ensembl Acc Id: ENST00000489702   ⟹   ENSP00000418037
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,612 - 128,950,027 (+)Ensembl
Ensembl Acc Id: ENST00000613821   ⟹   ENSP00000480058
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,940 - 128,947,256 (+)Ensembl
Ensembl Acc Id: ENST00000619830   ⟹   ENSP00000483292
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,940,838 - 128,948,982 (+)Ensembl
Ensembl Acc Id: ENST00000650798
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,938,217 - 128,947,256 (+)Ensembl
Ensembl Acc Id: ENST00000652142
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,938,029 - 128,947,295 (+)Ensembl
Ensembl Acc Id: ENST00000652525   ⟹   ENSP00000498293
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,457 - 128,942,224 (+)Ensembl
Ensembl Acc Id: ENST00000700148
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,937,783 - 128,950,027 (+)Ensembl
Ensembl Acc Id: ENST00000700149   ⟹   ENSP00000514825
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,939,378 - 128,942,224 (+)Ensembl
Ensembl Acc Id: ENST00000700150   ⟹   ENSP00000514826
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,939,378 - 128,942,224 (+)Ensembl
Ensembl Acc Id: ENST00000700151
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,943,781 - 128,950,027 (+)Ensembl
Ensembl Acc Id: ENST00000700152
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,943,781 - 128,950,027 (+)Ensembl
Ensembl Acc Id: ENST00000700153
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,944,186 - 128,950,027 (+)Ensembl
Ensembl Acc Id: ENST00000700154
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7128,947,606 - 128,950,017 (+)Ensembl
RefSeq Acc Id: NM_001098627   ⟹   NP_001092097
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,940,670 - 128,950,038 (+)NCBI
GRCh377128,577,976 - 128,590,089 (+)NCBI
Build 367128,368,008 - 128,377,325 (+)NCBI Archive
HuRef7122,939,186 - 122,951,277 (+)ENTREZGENE
CHM1_17128,513,996 - 128,523,404 (+)NCBI
T2T-CHM13v2.07130,253,596 - 130,262,927 (+)NCBI
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001098629   ⟹   NP_001092099
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,927 - 128,950,038 (+)NCBI
GRCh377128,577,976 - 128,590,089 (+)NCBI
Build 367128,365,230 - 128,377,325 (+)NCBI Archive
HuRef7122,939,186 - 122,951,277 (+)ENTREZGENE
CHM1_17128,511,263 - 128,523,404 (+)NCBI
T2T-CHM13v2.07130,250,853 - 130,262,927 (+)NCBI
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001098630   ⟹   NP_001092100
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,927 - 128,950,038 (+)NCBI
GRCh377128,577,976 - 128,590,089 (+)NCBI
Build 367128,365,230 - 128,377,325 (+)NCBI Archive
HuRef7122,939,186 - 122,951,277 (+)ENTREZGENE
CHM1_17128,511,263 - 128,523,404 (+)NCBI
T2T-CHM13v2.07130,250,853 - 130,262,927 (+)NCBI
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001242452   ⟹   NP_001229381
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,927 - 128,950,038 (+)NCBI
GRCh377128,577,976 - 128,590,089 (+)NCBI
HuRef7122,939,186 - 122,951,277 (+)ENTREZGENE
CHM1_17128,511,263 - 128,523,404 (+)NCBI
T2T-CHM13v2.07130,250,853 - 130,262,927 (+)NCBI
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001347928   ⟹   NP_001334857
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,032 - 128,950,038 (+)NCBI
T2T-CHM13v2.07130,249,958 - 130,262,927 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001364314   ⟹   NP_001351243
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,941,268 - 128,950,038 (+)NCBI
T2T-CHM13v2.07130,254,194 - 130,262,927 (+)NCBI
Sequence:
RefSeq Acc Id: NM_032643   ⟹   NP_116032
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,938,217 - 128,950,038 (+)NCBI
GRCh377128,577,976 - 128,590,089 (+)NCBI
Build 367128,365,507 - 128,377,325 (+)NCBI Archive
HuRef7122,939,186 - 122,951,277 (+)ENTREZGENE
CHM1_17128,511,543 - 128,523,404 (+)NCBI
T2T-CHM13v2.07130,251,143 - 130,262,927 (+)NCBI
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006715974   ⟹   XP_006716037
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,938,217 - 128,950,038 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011516158   ⟹   XP_011514460
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,940,670 - 128,950,038 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011516159   ⟹   XP_011514461
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,939,126 - 128,950,038 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011516160   ⟹   XP_011514462
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,032 - 128,950,038 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047420336   ⟹   XP_047276292
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,940,670 - 128,950,038 (+)NCBI
RefSeq Acc Id: XM_047420337   ⟹   XP_047276293
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,927 - 128,950,038 (+)NCBI
RefSeq Acc Id: XM_047420338   ⟹   XP_047276294
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,032 - 128,950,038 (+)NCBI
RefSeq Acc Id: XM_047420339   ⟹   XP_047276295
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,941,268 - 128,950,038 (+)NCBI
RefSeq Acc Id: XM_047420340   ⟹   XP_047276296
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,927 - 128,950,038 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001092097 (Get FASTA)   NCBI Sequence Viewer  
  NP_001092099 (Get FASTA)   NCBI Sequence Viewer  
  NP_001092100 (Get FASTA)   NCBI Sequence Viewer  
  NP_001229381 (Get FASTA)   NCBI Sequence Viewer  
  NP_001334857 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351243 (Get FASTA)   NCBI Sequence Viewer  
  NP_116032 (Get FASTA)   NCBI Sequence Viewer  
  XP_006716037 (Get FASTA)   NCBI Sequence Viewer  
  XP_011514460 (Get FASTA)   NCBI Sequence Viewer  
  XP_011514461 (Get FASTA)   NCBI Sequence Viewer  
  XP_011514462 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276292 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276293 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276294 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276295 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276296 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA96056 (Get FASTA)   NCBI Sequence Viewer  
  AAH04139 (Get FASTA)   NCBI Sequence Viewer  
  AAH04201 (Get FASTA)   NCBI Sequence Viewer  
  AAR90325 (Get FASTA)   NCBI Sequence Viewer  
  AAR90326 (Get FASTA)   NCBI Sequence Viewer  
  AAU12877 (Get FASTA)   NCBI Sequence Viewer  
  AAU12878 (Get FASTA)   NCBI Sequence Viewer  
  AAU12879 (Get FASTA)   NCBI Sequence Viewer  
  AAU12880 (Get FASTA)   NCBI Sequence Viewer  
  AAU12881 (Get FASTA)   NCBI Sequence Viewer  
  ABB88960 (Get FASTA)   NCBI Sequence Viewer  
  ABB88961 (Get FASTA)   NCBI Sequence Viewer  
  ABK41901 (Get FASTA)   NCBI Sequence Viewer  
  ABL96293 (Get FASTA)   NCBI Sequence Viewer  
  ABL96294 (Get FASTA)   NCBI Sequence Viewer  
  ABX54712 (Get FASTA)   NCBI Sequence Viewer  
  ABX54713 (Get FASTA)   NCBI Sequence Viewer  
  ABX54714 (Get FASTA)   NCBI Sequence Viewer  
  ABX54715 (Get FASTA)   NCBI Sequence Viewer  
  AFN70752 (Get FASTA)   NCBI Sequence Viewer  
  AFN70753 (Get FASTA)   NCBI Sequence Viewer  
  AFN70754 (Get FASTA)   NCBI Sequence Viewer  
  AFN70755 (Get FASTA)   NCBI Sequence Viewer  
  AFN70756 (Get FASTA)   NCBI Sequence Viewer  
  AKI32222 (Get FASTA)   NCBI Sequence Viewer  
  AKI32223 (Get FASTA)   NCBI Sequence Viewer  
  AKI32224 (Get FASTA)   NCBI Sequence Viewer  
  AKI32225 (Get FASTA)   NCBI Sequence Viewer  
  AKI32226 (Get FASTA)   NCBI Sequence Viewer  
  AKI32227 (Get FASTA)   NCBI Sequence Viewer  
  AKI32228 (Get FASTA)   NCBI Sequence Viewer  
  AKI32229 (Get FASTA)   NCBI Sequence Viewer  
  AKI32230 (Get FASTA)   NCBI Sequence Viewer  
  AKI32231 (Get FASTA)   NCBI Sequence Viewer  
  AKI32232 (Get FASTA)   NCBI Sequence Viewer  
  AKI32233 (Get FASTA)   NCBI Sequence Viewer  
  AKI32234 (Get FASTA)   NCBI Sequence Viewer  
  AKI32235 (Get FASTA)   NCBI Sequence Viewer  
  AKI32236 (Get FASTA)   NCBI Sequence Viewer  
  AKI32237 (Get FASTA)   NCBI Sequence Viewer  
  AKI32238 (Get FASTA)   NCBI Sequence Viewer  
  BAG59600 (Get FASTA)   NCBI Sequence Viewer  
  BAH11558 (Get FASTA)   NCBI Sequence Viewer  
  EAL24107 (Get FASTA)   NCBI Sequence Viewer  
  EAL24108 (Get FASTA)   NCBI Sequence Viewer  
  EAW83703 (Get FASTA)   NCBI Sequence Viewer  
  EAW83704 (Get FASTA)   NCBI Sequence Viewer  
  EAW83705 (Get FASTA)   NCBI Sequence Viewer  
  EAW83706 (Get FASTA)   NCBI Sequence Viewer  
  EAW83707 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000349770
  ENSP00000349770.5
  ENSP00000385352
  ENSP00000385352.2
  ENSP00000417454.1
  ENSP00000417770.1
  ENSP00000418037
  ENSP00000418037.2
  ENSP00000418534.1
  ENSP00000419056.1
  ENSP00000419149
  ENSP00000419149.1
  ENSP00000419950
  ENSP00000419950.1
  ENSP00000420274.1
  ENSP00000498293.1
  ENSP00000514825.1
  ENSP00000514826.1
GenBank Protein Q13568 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001092099   ⟸   NM_001098629
- Peptide Label: isoform d
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001092100   ⟸   NM_001098630
- Peptide Label: isoform b
- UniProtKB: Q6RCM8 (UniProtKB/Swiss-Prot),   Q64GB2 (UniProtKB/Swiss-Prot),   Q64GB1 (UniProtKB/Swiss-Prot),   Q64GA9 (UniProtKB/Swiss-Prot),   Q1A7B4 (UniProtKB/Swiss-Prot),   E7EW54 (UniProtKB/Swiss-Prot),   E7EQ16 (UniProtKB/Swiss-Prot),   A8DUA9 (UniProtKB/Swiss-Prot),   A8DUA8 (UniProtKB/Swiss-Prot),   A4D1J8 (UniProtKB/Swiss-Prot),   Q9BQF0 (UniProtKB/Swiss-Prot),   Q13568 (UniProtKB/Swiss-Prot),   A0A0G2UUJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001229381   ⟸   NM_001242452
- Peptide Label: isoform e
- UniProtKB: Q13568 (UniProtKB/Swiss-Prot),   B7Z1M2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_116032   ⟸   NM_032643
- Peptide Label: isoform b
- UniProtKB: A4D1J8 (UniProtKB/Swiss-Prot),   Q6RCM8 (UniProtKB/Swiss-Prot),   Q64GB2 (UniProtKB/Swiss-Prot),   Q64GB1 (UniProtKB/Swiss-Prot),   Q64GA9 (UniProtKB/Swiss-Prot),   Q1A7B4 (UniProtKB/Swiss-Prot),   E7EW54 (UniProtKB/Swiss-Prot),   E7EQ16 (UniProtKB/Swiss-Prot),   A8DUA9 (UniProtKB/Swiss-Prot),   A8DUA8 (UniProtKB/Swiss-Prot),   Q9BQF0 (UniProtKB/Swiss-Prot),   Q13568 (UniProtKB/Swiss-Prot),   A0A0G2UUJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001092097   ⟸   NM_001098627
- Peptide Label: isoform b
- UniProtKB: Q6RCM8 (UniProtKB/Swiss-Prot),   Q64GB2 (UniProtKB/Swiss-Prot),   Q64GB1 (UniProtKB/Swiss-Prot),   Q64GA9 (UniProtKB/Swiss-Prot),   Q1A7B4 (UniProtKB/Swiss-Prot),   E7EW54 (UniProtKB/Swiss-Prot),   E7EQ16 (UniProtKB/Swiss-Prot),   A8DUA9 (UniProtKB/Swiss-Prot),   A8DUA8 (UniProtKB/Swiss-Prot),   A4D1J8 (UniProtKB/Swiss-Prot),   Q9BQF0 (UniProtKB/Swiss-Prot),   Q13568 (UniProtKB/Swiss-Prot),   A0A0G2UUJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006716037   ⟸   XM_006715974
- Peptide Label: isoform X1
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011514462   ⟸   XM_011516160
- Peptide Label: isoform X1
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011514460   ⟸   XM_011516158
- Peptide Label: isoform X1
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011514461   ⟸   XM_011516159
- Peptide Label: isoform X1
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001334857   ⟸   NM_001347928
- Peptide Label: isoform d
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001351243   ⟸   NM_001364314
- Peptide Label: isoform d
- UniProtKB: A0A0G2USB5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000419950   ⟸   ENST00000477535
Ensembl Acc Id: ENSP00000419056   ⟸   ENST00000464557
Ensembl Acc Id: ENSP00000417770   ⟸   ENST00000479582
Ensembl Acc Id: ENSP00000418534   ⟸   ENST00000465603
Ensembl Acc Id: ENSP00000417454   ⟸   ENST00000467002
Ensembl Acc Id: ENSP00000385352   ⟸   ENST00000402030
Ensembl Acc Id: ENSP00000480058   ⟸   ENST00000613821
Ensembl Acc Id: ENSP00000498293   ⟸   ENST00000652525
Ensembl Acc Id: ENSP00000249375   ⟸   ENST00000249375
Ensembl Acc Id: ENSP00000483292   ⟸   ENST00000619830
Ensembl Acc Id: ENSP00000419149   ⟸   ENST00000473745
Ensembl Acc Id: ENSP00000420274   ⟸   ENST00000473787
Ensembl Acc Id: ENSP00000418037   ⟸   ENST00000489702
Ensembl Acc Id: ENSP00000349770   ⟸   ENST00000357234
RefSeq Acc Id: XP_047276294   ⟸   XM_047420338
- Peptide Label: isoform X3
- UniProtKB: Q6RCM8 (UniProtKB/Swiss-Prot),   Q64GB2 (UniProtKB/Swiss-Prot),   Q64GB1 (UniProtKB/Swiss-Prot),   Q64GA9 (UniProtKB/Swiss-Prot),   Q1A7B4 (UniProtKB/Swiss-Prot),   Q13568 (UniProtKB/Swiss-Prot),   E7EW54 (UniProtKB/Swiss-Prot),   E7EQ16 (UniProtKB/Swiss-Prot),   A8DUA9 (UniProtKB/Swiss-Prot),   A8DUA8 (UniProtKB/Swiss-Prot),   A4D1J8 (UniProtKB/Swiss-Prot),   Q9BQF0 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047276293   ⟸   XM_047420337
- Peptide Label: isoform X2
RefSeq Acc Id: XP_047276296   ⟸   XM_047420340
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047276292   ⟸   XM_047420336
- Peptide Label: isoform X1
RefSeq Acc Id: XP_047276295   ⟸   XM_047420339
- Peptide Label: isoform X3
- UniProtKB: Q6RCM8 (UniProtKB/Swiss-Prot),   Q64GB2 (UniProtKB/Swiss-Prot),   Q64GB1 (UniProtKB/Swiss-Prot),   Q64GA9 (UniProtKB/Swiss-Prot),   Q1A7B4 (UniProtKB/Swiss-Prot),   Q13568 (UniProtKB/Swiss-Prot),   E7EW54 (UniProtKB/Swiss-Prot),   E7EQ16 (UniProtKB/Swiss-Prot),   A8DUA9 (UniProtKB/Swiss-Prot),   A8DUA8 (UniProtKB/Swiss-Prot),   A4D1J8 (UniProtKB/Swiss-Prot),   Q9BQF0 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSP00000514825   ⟸   ENST00000700149
Ensembl Acc Id: ENSP00000514826   ⟸   ENST00000700150
Protein Domains
Interferon regulatory factor-3   IRF tryptophan pentad repeat

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q13568-F1-model_v2 AlphaFold Q13568 1-498 view protein structure

Promoters
RGD ID:6805831
Promoter ID:HG_KWN:59646
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:ENST00000342930,   NM_001098629,   NM_001098630,   NM_032643,   UC010LLR.1,   UC010LLS.1,   UC010LLT.1
Position:
Human AssemblyChrPosition (strand)Source
Build 367128,364,876 - 128,365,376 (+)MPROMDB
RGD ID:6805824
Promoter ID:HG_KWN:59647
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid,   NB4
Transcripts:UC003VOJ.2,   UC003VOK.2,   UC010LLU.1
Position:
Human AssemblyChrPosition (strand)Source
Build 367128,367,086 - 128,368,042 (+)MPROMDB
RGD ID:6805825
Promoter ID:HG_KWN:59648
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:UC010LLV.1,   UC010LLW.1
Position:
Human AssemblyChrPosition (strand)Source
Build 367128,368,521 - 128,369,702 (+)MPROMDB
RGD ID:6815616
Promoter ID:HG_MRA:15360
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:AL713733,   CU678589
Position:
Human AssemblyChrPosition (strand)Source
Build 367128,375,921 - 128,377,272 (+)MPROMDB
RGD ID:7211891
Promoter ID:EPDNEW_H11692
Type:initiation region
Name:IRF5_1
Description:interferon regulatory factor 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh387128,937,981 - 128,938,041EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6120 AgrOrtholog
COSMIC IRF5 COSMIC
Ensembl Genes ENSG00000128604 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000357234 ENTREZGENE
  ENST00000357234.10 UniProtKB/Swiss-Prot
  ENST00000402030 ENTREZGENE
  ENST00000402030.6 UniProtKB/Swiss-Prot
  ENST00000464557.5 UniProtKB/TrEMBL
  ENST00000465603.5 UniProtKB/Swiss-Prot
  ENST00000467002.1 UniProtKB/TrEMBL
  ENST00000473745 ENTREZGENE
  ENST00000473745.5 UniProtKB/Swiss-Prot
  ENST00000473787.5 UniProtKB/TrEMBL
  ENST00000477535 ENTREZGENE
  ENST00000477535.5 UniProtKB/Swiss-Prot
  ENST00000479582.5 UniProtKB/TrEMBL
  ENST00000489702 ENTREZGENE
  ENST00000489702.6 UniProtKB/Swiss-Prot
  ENST00000652525.1 UniProtKB/TrEMBL
  ENST00000700148 ENTREZGENE
  ENST00000700149.1 UniProtKB/TrEMBL
  ENST00000700150.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000128604 GTEx
HGNC ID HGNC:6120 ENTREZGENE
Human Proteome Map IRF5 Human Proteome Map
InterPro Interferon_reg_fac_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon_reg_fact_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon_reg_factor-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3663 UniProtKB/Swiss-Prot
NCBI Gene 3663 ENTREZGENE
OMIM 607218 OMIM
PANTHER INTERFERON REGULATORY FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11949:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA29919 PharmGKB
PRINTS INTFRNREGFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IRF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2UM11_HUMAN UniProtKB/TrEMBL
  A0A0G2USB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2UUJ1 ENTREZGENE, UniProtKB/TrEMBL
  A4D1J8 ENTREZGENE
  A8DUA8 ENTREZGENE
  A8DUA9 ENTREZGENE
  B7Z1M2 ENTREZGENE, UniProtKB/TrEMBL
  C9J7M2_HUMAN UniProtKB/TrEMBL
  C9JB67_HUMAN UniProtKB/TrEMBL
  C9JYP7_HUMAN UniProtKB/TrEMBL
  E7EQ16 ENTREZGENE
  E7EW54 ENTREZGENE
  F8WDH6_HUMAN UniProtKB/TrEMBL
  I6YQ35_HUMAN UniProtKB/TrEMBL
  I6Z0J2_HUMAN UniProtKB/TrEMBL
  I6ZKX6_HUMAN UniProtKB/TrEMBL
  I6ZU14_HUMAN UniProtKB/TrEMBL
  I6ZY36_HUMAN UniProtKB/TrEMBL
  IRF5_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q1A7B4 ENTREZGENE
  Q64GA8_HUMAN UniProtKB/TrEMBL
  Q64GA9 ENTREZGENE
  Q64GB0_HUMAN UniProtKB/TrEMBL
  Q64GB1 ENTREZGENE
  Q64GB2 ENTREZGENE
  Q6RCM8 ENTREZGENE
  Q9BQF0 ENTREZGENE
UniProt Secondary A4D1J8 UniProtKB/Swiss-Prot
  A8DUA8 UniProtKB/Swiss-Prot
  A8DUA9 UniProtKB/Swiss-Prot
  E7EQ16 UniProtKB/Swiss-Prot
  E7EW54 UniProtKB/Swiss-Prot
  Q1A7B4 UniProtKB/Swiss-Prot
  Q64GA9 UniProtKB/Swiss-Prot
  Q64GB1 UniProtKB/Swiss-Prot
  Q64GB2 UniProtKB/Swiss-Prot
  Q6RCM8 UniProtKB/Swiss-Prot
  Q9BQF0 UniProtKB/Swiss-Prot