Irf5 (interferon regulatory factor 5) - Rat Genome Database

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Gene: Irf5 (interferon regulatory factor 5) Mus musculus
Analyze
Symbol: Irf5
Name: interferon regulatory factor 5
RGD ID: 1321355
MGI Page MGI
Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific and protein kinase binding activity. Involved in cytokine-mediated signaling pathway; defense response to other organism; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in eye; ovary; telencephalon; and urinary system. Human ortholog(s) of this gene implicated in herpes simplex; inflammatory bowel disease 14; multiple sclerosis; rheumatoid arthritis; and systemic lupus erythematosus. Orthologous to human IRF5 (interferon regulatory factor 5); PARTICIPATES IN Toll-like receptor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW491843; interferon regulatory factor 5 bone marrow; IRF-5; mir; mirf5
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,526,129 - 29,541,874 (+)NCBIGRCm39mm39
GRCm39 Ensembl629,526,624 - 29,541,870 (+)Ensembl
GRCm38629,526,130 - 29,541,869 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,526,625 - 29,541,871 (+)EnsemblGRCm38mm10GRCm38
MGSCv37629,476,733 - 29,487,319 (+)NCBIGRCm37mm9NCBIm37
MGSCv36629,476,743 - 29,487,329 (+)NCBImm8
Celera629,535,579 - 29,546,163 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Alzaid F, etal., JCI Insight. 2016 Dec 8;1(20):e88689. doi: 10.1172/jci.insight.88689.
2. Bo M, etal., Clin Exp Rheumatol. 2018 May-Jun;36(3):376-381. Epub 2018 Jan 15.
3. Bo M, etal., J Transl Autoimmun. 2020 Mar 17;3:100048. doi: 10.1016/j.jtauto.2020.100048. eCollection 2020.
4. Bo M, etal., Sci Rep. 2018 Jan 29;8(1):1789. doi: 10.1038/s41598-018-19957-z.
5. Chen X, etal., J Biol Chem. 2017 Dec 29;292(52):21291-21303. doi: 10.1074/jbc.M117.805937. Epub 2017 Oct 18.
6. Cossu D, etal., Mult Scler. 2015 Jul;21(8):984-95. doi: 10.1177/1352458514557304. Epub 2014 Nov 12.
7. Fabié A, etal., Cell Rep. 2018 Jul 31;24(5):1163-1175. doi: 10.1016/j.celrep.2018.06.107.
8. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
9. Huang YH, etal., J Surg Res. 2011 Sep;170(1):e47-55. doi: 10.1016/j.jss.2011.05.033. Epub 2011 Jun 15.
10. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
11. Lu H, etal., Phytomedicine. 2019 Sep;62:152976. doi: 10.1016/j.phymed.2019.152976. Epub 2019 May 31.
12. Mai LT, etal., Front Immunol. 2020 Jan 21;10:3071. doi: 10.3389/fimmu.2019.03071. eCollection 2019.
13. Mapplebeck JCS, etal., Pain. 2018 Sep;159(9):1752-1763. doi: 10.1097/j.pain.0000000000001265.
14. MGD data from the GO Consortium
15. MGD IEA
16. Nie S, etal., Clin Immunol. 2019 Oct;207:24-35. doi: 10.1016/j.clim.2019.07.002. Epub 2019 Jul 4.
17. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
18. OMIM Disease Annotation Pipeline
19. Pipeline to import KEGG annotations from KEGG into RGD
20. Proenca-Modena JL, etal., J Virol. 2015 Oct 14;90(1):189-205. doi: 10.1128/JVI.02276-15.
21. RGD automated import pipeline
22. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. RGD automated import pipeline for gene-chemical interactions
24. Thackray LB, etal., J Virol. 2014 Oct;88(19):11007-21. doi: 10.1128/JVI.01545-14. Epub 2014 Jul 16.
25. Urdzíková LM, etal., Int J Mol Sci. 2014 Jun 25;15(7):11275-93. doi: 10.3390/ijms150711275.
26. Vandenbroeck K, etal., Genes Immun. 2011 Jan;12(1):40-5. doi: 10.1038/gene.2010.46. Epub 2010 Sep 23.
27. Wang X, etal., Med Sci Monit. 2018 May 30;24:3620-3630. doi: 10.12659/MSM.910756.
28. Xiao Y, etal., Mol Med. 2017 Sep;23:166-176. doi: 10.2119/molmed.2016.00243. Epub 2017 Jun 14.
29. Zhang M, etal., Mol Med Rep. 2017 Apr;15(4):2318-2324. doi: 10.3892/mmr.2017.6229. Epub 2017 Feb 22.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10788617   PMID:11042159   PMID:11076861   PMID:15665823   PMID:16141072   PMID:16141073   PMID:16236719   PMID:16602821   PMID:17275788   PMID:17360658  
PMID:17507094   PMID:17513736   PMID:18268344   PMID:18287559   PMID:18332133   PMID:18824541   PMID:19028697   PMID:19430534   PMID:19652017   PMID:19798431   PMID:20007534   PMID:20059953  
PMID:20176957   PMID:20211142   PMID:20351107   PMID:20451243   PMID:20456021   PMID:20479222   PMID:20802013   PMID:20935208   PMID:21240265   PMID:21253574   PMID:21267068   PMID:21305501  
PMID:21677750   PMID:21820332   PMID:21835795   PMID:21873635   PMID:22116829   PMID:22366192   PMID:22422888   PMID:22431588   PMID:22535200   PMID:22610141   PMID:22678902   PMID:22784990  
PMID:22933628   PMID:22988430   PMID:23142781   PMID:23213237   PMID:23251680   PMID:23291967   PMID:23300459   PMID:23770228   PMID:23912454   PMID:24361318   PMID:24376264   PMID:24453413  
PMID:24818655   PMID:24866378   PMID:25076492   PMID:25149452   PMID:25288773   PMID:25326418   PMID:25326420   PMID:25595782   PMID:25939064   PMID:26046638   PMID:26283380   PMID:26358260  
PMID:26598674   PMID:27050551   PMID:27521268   PMID:27545875   PMID:27759022   PMID:27825654   PMID:27895424   PMID:28099860   PMID:28158275   PMID:28237967   PMID:28400473   PMID:28468974  
PMID:28515358   PMID:28636955   PMID:28695899   PMID:28698173   PMID:28746869   PMID:28820065   PMID:28905935   PMID:29075020   PMID:29117564   PMID:29483597   PMID:29562174   PMID:30451651  
PMID:30457675   PMID:30830879   PMID:30902986   PMID:31053739   PMID:31086271   PMID:31127629   PMID:31420465   PMID:31799619   PMID:31892541   PMID:31999809   PMID:32014112   PMID:32444476  
PMID:32456211   PMID:32610123   PMID:32690658   PMID:32776630   PMID:32897883   PMID:33278357   PMID:33362784   PMID:33423291   PMID:34282144  


Genomics

Comparative Map Data
Irf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39629,526,129 - 29,541,874 (+)NCBIGRCm39mm39
GRCm39 Ensembl629,526,624 - 29,541,870 (+)Ensembl
GRCm38629,526,130 - 29,541,869 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl629,526,625 - 29,541,871 (+)EnsemblGRCm38mm10GRCm38
MGSCv37629,476,733 - 29,487,319 (+)NCBIGRCm37mm9NCBIm37
MGSCv36629,476,743 - 29,487,329 (+)NCBImm8
Celera629,535,579 - 29,546,163 (+)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.36NCBI
IRF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7128,937,457 - 128,950,038 (+)EnsemblGRCh38hg38GRCh38
GRCh387128,937,032 - 128,950,038 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377128,577,086 - 128,590,092 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367128,365,230 - 128,377,325 (+)NCBINCBI36hg18NCBI36
Build 347128,172,221 - 128,184,037NCBI
Celera7123,374,509 - 123,386,585 (+)NCBI
Cytogenetic Map7q32.1NCBI
HuRef7122,939,186 - 122,951,277 (+)NCBIHuRef
CHM1_17128,511,266 - 128,523,397 (+)NCBICHM1_1
CRA_TCAGchr7v27127,961,737 - 127,973,832 (+)NCBI
Irf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2458,127,577 - 58,140,665 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl458,127,640 - 58,139,267 (+)Ensembl
Rnor_6.0456,804,477 - 56,816,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl456,805,132 - 56,820,543 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0456,571,823 - 56,583,434 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4456,407,560 - 56,418,694 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1456,666,980 - 56,677,876 (+)NCBI
Celera453,236,000 - 53,247,024 (+)NCBICelera
Cytogenetic Map4q22NCBI
IRF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17133,415,170 - 133,426,356 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7133,415,170 - 133,426,356 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07120,889,752 - 120,902,096 (+)NCBIMhudiblu_PPA_v0panPan3
IRF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,724,168 - 7,734,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,724,780 - 7,742,795 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha147,411,116 - 7,421,966 (-)NCBI
ROS_Cfam_1.0147,490,116 - 7,500,966 (-)NCBI
UMICH_Zoey_3.1147,695,157 - 7,706,007 (-)NCBI
UNSW_CanFamBas_1.0147,437,183 - 7,448,035 (-)NCBI
UU_Cfam_GSD_1.0147,582,360 - 7,592,901 (-)NCBI
Irf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511826,005,766 - 26,016,934 (-)NCBI
SpeTri2.0NW_0049365796,138,372 - 6,149,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1819,678,686 - 19,691,154 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11819,678,377 - 19,691,154 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21820,748,271 - 20,760,087 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IRF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12197,536,803 - 97,549,576 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2197,537,790 - 97,549,945 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660425,852,040 - 5,864,687 (-)NCBIVero_WHO_p1.0
Irf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247837,267,680 - 7,275,918 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AW491843  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38629,537,109 - 29,537,218UniSTSGRCm38
MGSCv37629,487,109 - 29,487,218UniSTSGRCm37
Celera629,545,953 - 29,546,062UniSTS
Cytogenetic Map6A3.3UniSTS
Whitehead/MRC_RH6232.19UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301131Chol2_mcholesterol 2 (mouse)Not determined6132144496Mouse
5491191Mobq2_mmultigenic obesity QTL 2 (mouse)Not determined6132144496Mouse
1302024Skull7_mskull morphology 7 (mouse)Not determined6132144496Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
15039372Nmrs22_mNAFLD-associated magnetic resonance shift 22 (mouse)6147633535476335Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300731Smdq3_msegregation of mitochondrial DNA QTL 3 (mouse)Not determined6424920738249326Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
11353836Bmiq1_mbody mass index QTL 1 (mouse)6450382329751334Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345314181Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348726677Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348726677Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348726677Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707543297169Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797246118070Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122246751334Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122246751334Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61770000053500000Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61773466351734784Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1773466351734784Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61773466351734784Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61963941153639411Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61963941153639411Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61963941153639411Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268671322775Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62007289554072895Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62380000057800000Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2831405962314181Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1045
Count of miRNA genes:479
Interacting mature miRNAs:568
Transcripts:ENSMUST00000004392, ENSMUST00000163511, ENSMUST00000164626, ENSMUST00000164922, ENSMUST00000167252, ENSMUST00000171527
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001252382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001311083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_012057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC079276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF028725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF177019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW491843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY749561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY749804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU401974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000004392   ⟹   ENSMUSP00000004392
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl629,526,624 - 29,537,318 (+)Ensembl
GRCm38.p6 Ensembl629,526,625 - 29,537,319 (+)Ensembl
RefSeq Acc Id: ENSMUST00000163511   ⟹   ENSMUSP00000127021
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl629,529,281 - 29,537,318 (+)Ensembl
GRCm38.p6 Ensembl629,529,282 - 29,537,319 (+)Ensembl
RefSeq Acc Id: ENSMUST00000164626   ⟹   ENSMUSP00000130548
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl629,528,269 - 29,533,996 (+)Ensembl
GRCm38.p6 Ensembl629,528,270 - 29,533,997 (+)Ensembl
RefSeq Acc Id: ENSMUST00000164922   ⟹   ENSMUSP00000145299
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl629,531,247 - 29,535,345 (+)Ensembl
GRCm38.p6 Ensembl629,531,248 - 29,535,346 (+)Ensembl
RefSeq Acc Id: ENSMUST00000167252   ⟹   ENSMUSP00000126273
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl629,526,707 - 29,541,870 (+)Ensembl
GRCm38.p6 Ensembl629,526,708 - 29,541,871 (+)Ensembl
RefSeq Acc Id: ENSMUST00000171527
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl629,541,145 - 29,541,857 (+)Ensembl
GRCm38.p6 Ensembl629,541,146 - 29,541,858 (+)Ensembl
RefSeq Acc Id: NM_001252382   ⟹   NP_001239311
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,529,281 - 29,537,319 (+)NCBI
GRCm38629,529,282 - 29,537,320 (+)NCBI
Celera629,535,471 - 29,546,164 (+)ENTREZGENE
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001311083   ⟹   NP_001298012
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,526,624 - 29,541,868 (+)NCBI
GRCm38629,526,625 - 29,541,869 (+)NCBI
Sequence:
RefSeq Acc Id: NM_012057   ⟹   NP_036187
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,526,624 - 29,537,319 (+)NCBI
GRCm38629,526,625 - 29,537,320 (+)NCBI
MGSCv37629,476,733 - 29,487,319 (+)RGD
Celera629,535,471 - 29,546,164 (+)ENTREZGENE
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505095   ⟹   XP_006505158
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,526,129 - 29,541,874 (+)NCBI
GRCm38629,526,130 - 29,537,320 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505097   ⟹   XP_006505160
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,528,245 - 29,541,874 (+)NCBI
GRCm38629,528,201 - 29,537,320 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505098   ⟹   XP_006505161
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,526,624 - 29,541,874 (+)NCBI
GRCm38629,526,625 - 29,537,320 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505099   ⟹   XP_006505162
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,529,259 - 29,541,874 (+)NCBI
GRCm38629,529,253 - 29,537,320 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505100   ⟹   XP_006505163
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,528,249 - 29,541,874 (+)NCBI
GRCm38629,528,238 - 29,537,320 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255430   ⟹   XP_030111290
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39629,528,082 - 29,541,874 (+)NCBI
GRCm38629,528,058 - 29,537,320 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_036187   ⟸   NM_012057
- Peptide Label: isoform 2
- UniProtKB: P56477 (UniProtKB/Swiss-Prot),   Q3U169 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001239311   ⟸   NM_001252382
- Peptide Label: isoform 1
- UniProtKB: P56477 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006505158   ⟸   XM_006505095
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006505161   ⟸   XM_006505098
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006505160   ⟸   XM_006505097
- Peptide Label: isoform X3
- UniProtKB: P56477 (UniProtKB/Swiss-Prot),   Q3U169 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505163   ⟸   XM_006505100
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006505162   ⟸   XM_006505099
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: NP_001298012   ⟸   NM_001311083
- Peptide Label: isoform 3
- UniProtKB: F6Z6C6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111290   ⟸   XM_030255430
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000145299   ⟸   ENSMUST00000164922
RefSeq Acc Id: ENSMUSP00000130548   ⟸   ENSMUST00000164626
RefSeq Acc Id: ENSMUSP00000127021   ⟸   ENSMUST00000163511
RefSeq Acc Id: ENSMUSP00000126273   ⟸   ENSMUST00000167252
RefSeq Acc Id: ENSMUSP00000004392   ⟸   ENSMUST00000004392
Promoters
RGD ID:6839511
Promoter ID:MM_KWN:45380
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000004392,   UC009BDV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36629,476,594 - 29,477,094 (+)MPROMDB
RGD ID:6839510
Promoter ID:MM_KWN:45381
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Lung
Transcripts:UC009BDW.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36629,478,301 - 29,479,387 (+)MPROMDB
RGD ID:6849202
Promoter ID:MM_XEF:5856
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour
Transcripts:NM_001031587,   NM_001035465,   NM_001094596,   NM_001098627,   NM_001098628,   NM_001098629,   NM_001098630,   NM_001098631,   NM_001139852,   NM_002200,   NM_032643,   NM_212875
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36629,481,069 - 29,481,569 (+)MPROMDB
RGD ID:6848002
Promoter ID:MM_ACW:40720
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney,   Liver
Transcripts:IRF5.ESEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36629,484,196 - 29,485,852 (+)MPROMDB
RGD ID:6889192
Promoter ID:EPDNEW_M8047
Type:initiation region
Name:Irf5_1
Description:Mus musculus interferon regulatory factor 5 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8048  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38629,526,699 - 29,526,759EPDNEW
RGD ID:6889194
Promoter ID:EPDNEW_M8048
Type:initiation region
Name:Irf5_2
Description:Mus musculus interferon regulatory factor 5 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8047  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38629,529,291 - 29,529,351EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1350924 AgrOrtholog
Ensembl Genes ENSMUSG00000029771 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000004392 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000126273 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000127021 UniProtKB/Swiss-Prot
  ENSMUSP00000130548 UniProtKB/TrEMBL
  ENSMUSP00000145299 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000004392 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000163511 UniProtKB/Swiss-Prot
  ENSMUST00000164626 UniProtKB/TrEMBL
  ENSMUST00000164922 UniProtKB/TrEMBL
  ENSMUST00000167252 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Interferon_reg_fac_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon_reg_fact_DNA-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interferon_reg_factor-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:27056 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1350924 ENTREZGENE
NCBI Gene 27056 ENTREZGENE
PANTHER PTHR11949 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11949:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Irf5 PhenoGen
PRINTS INTFRNREGFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IRF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IRF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRF-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49879 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0N4SVY5_MOUSE UniProtKB/TrEMBL
  B2CC69_MOUSE UniProtKB/TrEMBL
  E9Q5T2_MOUSE UniProtKB/TrEMBL
  F6Z6C6 ENTREZGENE, UniProtKB/TrEMBL
  IRF5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3U169 ENTREZGENE, UniProtKB/TrEMBL