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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cycloheximide
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Accession:CHEBI:27641 term browser browse the term
Definition:A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.
Synonyms:exact_synonym: 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
 related_synonym: 3-((R)-2-((1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide;   Cycloheximid;   Formula=C15H23NO4;   InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1;   InChIKey=YPHMISFOHDHNIV-FSZOTQKASA-N;   SMILES=[H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC1CC(=O)NC(=O)C1;   Zykloheximid;   cicloheximida;   cicloheximide;   cicloheximidum;   naramycin;   naramycin A
 alt_id: CHEBI:23484;   CHEBI:4015
 xref: Beilstein:88868;   CAS:66-81-9;   KEGG:C06685;   KEGG:D03625;   KNApSAcK:C00047211;   LINCS:LSM-2791
 xref_mesh: MESH:D003513
 xref: PDBeChem:3HE;   PMID:11972861;   PMID:16659174;   PMID:25209664;   PMID:26715760;   PMID:27192630;   PMID:27665925;   PMID:30154175;   PMID:30916348;   PMID:32299921;   PMID:33101237;   PPDB:1680;   Reaxys:88868;   Wikipedia:Cycloheximide



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cycloheximide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 5031439G07Rik RIKEN cDNA 5031439G07 gene multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KIAA0930 mRNA CTD PMID:19684285 NCBI chr15:84,828,137...84,872,503
Ensembl chr15:84,828,137...84,872,752
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions
increases expression
ISO Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]
Cycloheximide results in increased expression of ABCB1 mRNA
Cycloheximide inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Cycloheximide inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Cycloheximide inhibits the reaction [tetrabromobisphenol A results in increased expression of and results in increased activity of ABCB1A protein]; Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]
CTD PMID:7476894 PMID:18474546 PMID:30830211 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] CTD PMID:11331069 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of ABCC3 mRNA
Cycloheximide results in increased expression of ABCC3 mRNA
CTD PMID:15072547 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of ABCC5 mRNA
Cycloheximide results in decreased expression of ABCC5 mRNA
CTD PMID:15072547 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of ACSL3 mRNA CTD PMID:19684285 NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO Cycloheximide inhibits the reaction [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of ACSL6 mRNA] CTD PMID:10585473 NCBI chr11:54,194,580...54,255,582
Ensembl chr11:54,194,624...54,255,582
JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 multiple interactions
decreases stability
ISO cordycepin inhibits the reaction [Cycloheximide results in decreased stability of ADAM17 protein]; N(6),N(6)-dimethyladenosine inhibits the reaction [Cycloheximide results in decreased stability of ADAM17 protein] CTD PMID:36558177 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr 8:25,439,627...25,507,138
Ensembl chr 8:25,439,627...25,506,943
JBrowse link
G Adm adrenomedullin multiple interactions
increases expression
ISO Cycloheximide promotes the reaction [Oxygen deficiency results in increased expression of ADM mRNA]
Cycloheximide results in increased expression of ADM mRNA
CTD PMID:11032871 NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027
JBrowse link
G Adora2b adenosine A2b receptor multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ADORA2B mRNA CTD PMID:19684285 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279
JBrowse link
G Adrb2 adrenergic receptor, beta 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of ADRB2 mRNA; Cycloheximide results in increased expression of ADRB2 protein
[Cycloheximide co-treated with EDN1 protein] results in increased expression of ADRB2 mRNA; Cycloheximide inhibits the reaction [olodaterol affects the expression of ADRB2 mRNA]; Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of ADRB2 protein]; Formoterol Fumarate promotes the reaction [Cycloheximide results in increased expression of ADRB2 mRNA]; N(6)-benzoyl-cyclic AMP promotes the reaction [Cycloheximide results in increased expression of ADRB2 mRNA]
CTD PMID:22483689 PMID:24705868 NCBI chr18:62,310,784...62,313,052
Ensembl chr18:62,310,887...62,313,030
JBrowse link
G Ago3 argonaute RISC catalytic subunit 3 multiple interactions EXP Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] CTD PMID:29576526 NCBI chr 4:126,220,797...126,323,360
Ensembl chr 4:126,225,497...126,323,349
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
decreases expression
increases localization
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of AHR protein]; Cycloheximide inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased degradation of and results in decreased expression of AHR protein]
Cycloheximide results in increased localization of AHR protein
[Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]] which results in increased expression of CYP1A1 mRNA; [Tretinoin co-treated with Cycloheximide] results in increased expression of AHR mRNA; AHR protein promotes the reaction [Cycloheximide results in increased expression of TIPARP mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin affects the localization of AHR protein]; Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]
CTD PMID:9145908 PMID:10777561 PMID:12002481 PMID:12147270 PMID:15385644 More... NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Akap5 A kinase anchor protein 5 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKAP5 mRNA] CTD PMID:11007951 NCBI chr12:76,371,652...76,380,925
Ensembl chr12:76,371,665...76,380,927
JBrowse link
G Akap6 A kinase anchor protein 6 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKAP6 mRNA] CTD PMID:11007951 NCBI chr12:52,745,371...53,202,351
Ensembl chr12:52,746,166...53,202,382
JBrowse link
G Akr1c18 aldo-keto reductase family 1, member C18 multiple interactions ISO Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] CTD PMID:21787718 NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 multiple interactions
increases phosphorylation
ISO Cycloheximide inhibits the reaction [[Hydrogen Peroxide co-treated with sodium arsenite] results in increased phosphorylation of AKT1 protein]
Cycloheximide results in increased phosphorylation of AKT1 protein
CTD PMID:12472888 PMID:28634229 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ALDH1A3 mRNA CTD PMID:19684285 NCBI chr 7:66,040,640...66,077,225
Ensembl chr 7:66,040,638...66,077,265
JBrowse link
G Aldh3a1 aldehyde dehydrogenase family 3, subfamily A1 multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of ALDH3A1 mRNA] CTD PMID:1953764 NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247
JBrowse link
G Aldh3a2 aldehyde dehydrogenase family 3, subfamily A2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ALDH3A2 mRNA CTD PMID:19684285 NCBI chr11:61,114,240...61,158,267
Ensembl chr11:61,114,243...61,158,290
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALOX5AP mRNA] CTD PMID:11007951 NCBI chr 5:149,201,814...149,224,963
Ensembl chr 5:149,201,577...149,224,963
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases activity
multiple interactions
ISO Cycloheximide results in decreased activity of ALPI protein
Cycloheximide inhibits the reaction [Fish Oils results in increased activity of ALPI protein]
CTD PMID:15599000 PMID:20362602 NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328
JBrowse link
G Amhr2 anti-Mullerian hormone type 2 receptor multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AMHR2 mRNA] CTD PMID:11007951 NCBI chr15:102,353,437...102,363,075
Ensembl chr15:102,353,802...102,363,068
JBrowse link
G Ank2 ankyrin 2, brain multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ANK2 mRNA] CTD PMID:11007951 NCBI chr 3:126,715,256...127,293,996
Ensembl chr 3:126,715,261...127,292,999
JBrowse link
G Ankrd27 ankyrin repeat domain 27 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ANKRD27 mRNA CTD PMID:19684285 NCBI chr 7:35,285,652...35,338,662
Ensembl chr 7:35,285,669...35,338,651
JBrowse link
G Aoc1 amine oxidase, copper-containing 1 multiple interactions ISO Cycloheximide inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Cycloheximide inhibits the reaction [Terbutaline results in increased activity of AOC1 protein] CTD PMID:2860926 PMID:6218830 NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of APAF1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of APAF1 mRNA
CTD PMID:19684285 NCBI chr10:90,825,173...90,918,688
Ensembl chr10:90,825,173...90,918,632
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of AQP1 mRNA] CTD PMID:22415096 NCBI chr 6:55,313,284...55,325,540
Ensembl chr 6:55,313,417...55,325,540
JBrowse link
G Aqp4 aquaporin 4 multiple interactions ISO [Lactic Acid co-treated with Cycloheximide] results in increased expression of AQP4 protein CTD PMID:18406487 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039
JBrowse link
G Areg amphiregulin multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of AREG mRNA
Cycloheximide results in increased expression of AREG mRNA
CTD PMID:15072547 PMID:15228094 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Armc5 armadillo repeat containing 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ARMC5 mRNA CTD PMID:19684285 NCBI chr 7:127,836,460...127,844,272
Ensembl chr 7:127,836,514...127,844,272
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions EXP [Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]] which results in increased expression of CYP1A1 mRNA; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide results in increased activity of [AHR protein binds to ARNT protein] CTD PMID:12002481 PMID:20570689 NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ASB1 mRNA CTD PMID:19684285 NCBI chr 1:91,467,725...91,487,312
Ensembl chr 1:91,468,266...91,487,311
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions EXP Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein] CTD PMID:23593480 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of ATF4]]; Cycloheximide inhibits the reaction [Capsaicin results in increased expression of ATF4 protein]
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein]
CTD PMID:18533110 PMID:23593480 PMID:24057571 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atg13 autophagy related 13 decreases expression ISO Cycloheximide results in decreased expression of ATG13 protein CTD PMID:27629431 NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921
JBrowse link
G Atp7a ATPase, Cu++ transporting, alpha polypeptide multiple interactions
decreases expression
ISO cupric chloride inhibits the reaction [Cycloheximide results in decreased expression of ATP7A protein] CTD PMID:23174565 NCBI chr  X:105,070,830...105,171,766
Ensembl chr  X:105,070,882...105,168,532
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AVPR1A mRNA] CTD PMID:11007951 NCBI chr10:122,284,404...122,289,358
Ensembl chr10:122,284,404...122,289,357
JBrowse link
G Bach1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of BACH1 protein
tetrachlorobenzoquinone promotes the reaction [Cycloheximide results in decreased expression of BACH1 protein]
CTD PMID:27393035 NCBI chr16:87,495,842...87,530,234
Ensembl chr16:87,495,833...87,530,234
JBrowse link
G Bap1 Brca1 associated protein 1 multiple interactions EXP BAP1 inhibits the reaction [Cycloheximide results in increased degradation of BRCA1 protein] CTD PMID:37414201 NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of BAX protein] CTD PMID:9790906 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BBOX1 mRNA] CTD PMID:11007951 NCBI chr 2:110,094,401...110,145,158
Ensembl chr 2:110,093,042...110,144,905
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO BCL2 protein inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased expression of BCL2 protein]; Cycloheximide inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein] CTD PMID:11726273 PMID:22343715 PMID:34303041 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of BCL2L1 protein alternative form
Dexamethasone inhibits the reaction [Cycloheximide results in increased expression of BCL2L1 protein]
CTD PMID:9326359 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bcl2l14 BCL2 like 14 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of BCL2L14 mRNA CTD PMID:19684285 NCBI chr 6:134,373,292...134,415,687
Ensembl chr 6:134,373,281...134,415,699
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase, type 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of BDH1 mRNA] CTD PMID:11007951 NCBI chr16:31,241,115...31,277,719
Ensembl chr16:31,241,098...31,277,719
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions ISO Cycloheximide inhibits the reaction [arsenic trioxide results in increased expression of BECN1 protein] CTD PMID:16882451 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bglap bone gamma carboxyglutamate protein multiple interactions EXP Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of BGLAP mRNA]; Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of BGLAP mRNA] CTD PMID:17203194 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Cycloheximide co-treated with TNF] results in increased cleavage of BID protein; Cycloheximide inhibits the reaction [vorinostat results in increased cleavage of BID protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein] CTD PMID:11535817 PMID:12925536 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Bnip3 BCL2/adenovirus E1B interacting protein 3 multiple interactions EXP Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein] CTD PMID:19442826 NCBI chr 7:138,492,565...138,511,235
Ensembl chr 7:138,492,565...138,511,248
JBrowse link
G Brca1 breast cancer 1, early onset multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA1 mRNA]
BAP1 inhibits the reaction [Cycloheximide results in increased degradation of BRCA1 protein]; Cycloheximide inhibits the reaction [Thapsigargin affects the localization of BRCA1 mRNA]
CTD PMID:10344722 PMID:29576526 PMID:37414201 NCBI chr11:101,379,587...101,442,808
Ensembl chr11:101,379,590...101,442,781
JBrowse link
G Brca2 breast cancer 2, early onset multiple interactions ISO Cycloheximide inhibits the reaction [Nitrogen Mustard Compounds results in decreased expression of BRCA2 mRNA] CTD PMID:10344722 NCBI chr 5:150,445,759...150,493,612
Ensembl chr 5:150,446,095...150,493,794
JBrowse link
G Calb1 calbindin 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CALB1 mRNA] CTD PMID:11007951 NCBI chr 4:15,881,264...15,906,709
Ensembl chr 4:15,881,264...15,908,064
JBrowse link
G Caml calcium modulating ligand multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CAMLG mRNA] CTD PMID:11007951 NCBI chr13:55,770,818...55,780,229
Ensembl chr13:55,770,818...55,780,224
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of CASP1 protein]; Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CASP1 mRNA] CTD PMID:11007951 PMID:26901245 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO
EXP
[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein]; Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP3 protein]; IFI6 protein inhibits the reaction [Cycloheximide results in increased activity of CASP3 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein]
obeticholic acid promotes the reaction [Cycloheximide results in increased activity of CASP3 protein]
Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [aluminum maltolate results in increased activity of CASP3 protein]; Cycloheximide inhibits the reaction [Cryptoxanthins promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc Sulfate promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]
CTD PMID:12760867 PMID:12925536 PMID:14502240 PMID:15537749 PMID:15685448 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp4 caspase 4, apoptosis-related cysteine peptidase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CASP4 mRNA] CTD PMID:11007951 NCBI chr 9:5,308,816...5,336,791
Ensembl chr 9:5,308,828...5,336,783
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in increased expression of CASP7 mRNA]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein] CTD PMID:12760867 PMID:16166294 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP8 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein]
Cycloheximide results in increased activity of CASP8 protein
CTD PMID:12760867 PMID:12925536 PMID:15924153 PMID:18222423 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO
EXP
[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein]
Cycloheximide results in increased activity of CASP9 protein
CTD PMID:12925536 PMID:14502240 PMID:18222423 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO Cycloheximide inhibits the reaction [Clofibrate results in increased expression of CAT protein]; Cycloheximide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CAT protein] CTD PMID:6845354 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Catsper4 cation channel, sperm associated 4 affects response to substance ISO CATSPER4 gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 4:133,939,276...133,954,743
Ensembl chr 4:133,939,281...133,954,694
JBrowse link
G Cav1 caveolin 1, caveolae protein multiple interactions ISO Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] CTD PMID:15314095 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Cbx1 chromobox 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CBX1 mRNA CTD PMID:19684285 NCBI chr11:96,679,506...96,699,808
Ensembl chr11:96,679,953...96,699,466
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]] CTD PMID:21146893 PMID:22121136 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CCL5 mRNA
Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]]
CTD PMID:21146893 PMID:22121136 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein] CTD PMID:21055460 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CCN2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCN2 mRNA
CTD PMID:19684285 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581
JBrowse link
G Ccn3 cellular communication network factor 3 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of CCN3 mRNA
Cycloheximide results in increased expression of CCN3 mRNA
CTD PMID:15072547 NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435
JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions ISO Cycloheximide inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA] CTD PMID:19238344 NCBI chr15:66,763,337...66,795,050
Ensembl chr15:66,763,169...66,795,050
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of CCNA2 mRNA
Cycloheximide results in decreased expression of CCNA2 mRNA
CTD PMID:15072547 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [gingerol co-treated with Cycloheximide] results in increased degradation of CCND1 protein; Cycloheximide inhibits the reaction [CXCL8 protein results in increased expression of CCND1 protein]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of CCND1 protein]] CTD PMID:17606477 PMID:18058799 PMID:25923732 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccnd3 cyclin D3 affects expression
multiple interactions
EXP Cycloheximide affects the expression of CCND3 mRNA
Cycloheximide affects the reaction [Estradiol affects the expression of CCND3 mRNA]
CTD PMID:9094091 NCBI chr17:47,815,976...47,910,614
Ensembl chr17:47,815,976...47,910,616
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCT5 mRNA CTD PMID:19684285 NCBI chr15:31,590,946...31,601,992
Ensembl chr15:31,590,946...31,601,950
JBrowse link
G Cd38 CD38 antigen multiple interactions ISO Cycloheximide affects the reaction [Tretinoin results in increased expression of CD38 mRNA] CTD PMID:21393419 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717
JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD3E mRNA] CTD PMID:11007951 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925
JBrowse link
G Cd44 CD44 antigen multiple interactions EXP Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein] CTD PMID:9929743 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CD47 mRNA] CTD PMID:11007951 NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373
JBrowse link
G Cd63 CD63 antigen multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD63 mRNA] CTD PMID:11007951 NCBI chr10:128,731,577...128,748,691
Ensembl chr10:128,736,858...128,748,691
JBrowse link
G Cd8a CD8 subunit alpha multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CD8A mRNA CTD PMID:19684285 NCBI chr 6:71,350,411...71,356,155
Ensembl chr 6:71,350,411...71,356,157
JBrowse link
G Cdc42se2 CDC42 small effector 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CDC42SE2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of CDC42SE2 mRNA
CTD PMID:19684285 NCBI chr11:54,608,241...54,678,549
Ensembl chr11:54,608,282...54,678,501
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CDCA5 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CDCA5 mRNA
CTD PMID:19684285 NCBI chr19:6,135,127...6,141,803
Ensembl chr19:6,135,013...6,141,807
JBrowse link
G Cdca7l cell division cycle associated 7 like multiple interactions ISO Cycloheximide inhibits the reaction [TAK-243 results in increased sumoylation of CDCA7L protein] CTD PMID:31285264 NCBI chr12:117,807,209...117,842,441
Ensembl chr12:117,768,024...117,842,441
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of CDK2 mRNA] CTD PMID:12800980 NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions
decreases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Cycloheximide results in decreased expression of CDKN1A protein]; Cycloheximide inhibits the reaction [Resveratrol results in increased expression of CDKN1A mRNA]; Cycloheximide inhibits the reaction [Troglitazone results in increased expression of CDKN1A protein]; Furazolidone promotes the reaction [Cycloheximide results in decreased expression of CDKN1A protein]; IGF1 protein inhibits the reaction [Cycloheximide results in decreased expression of CDKN1A protein]; PSME3 protein affects the reaction [Cycloheximide results in decreased expression of CDKN1A protein]
Cycloheximide results in decreased expression of CDKN1A mRNA; Cycloheximide results in decreased expression of CDKN1A protein
Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
Cycloheximide promotes the reaction [Dexamethasone results in decreased expression of CDKN1A protein]; Cycloheximide promotes the reaction [Semaxinib results in increased expression of CDKN1A mRNA]
CTD PMID:10441511 PMID:12690110 PMID:22542671 PMID:24211769 PMID:26687534 More... NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2a cyclin dependent kinase inhibitor 2A increases expression ISO Cycloheximide results in increased expression of CDKN2A mRNA CTD PMID:17257637 NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of CFLAR protein; Cycloheximide results in decreased expression of CFLAR protein alternative form; Cycloheximide results in decreased expression of CFLAR protein modified form
shogaol promotes the reaction [Cycloheximide results in decreased expression of CFLAR protein modified form]
CTD PMID:12663669 PMID:15924153 PMID:16077199 PMID:16951203 PMID:25619640 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator affects expression ISO Cycloheximide affects the expression of CFTR mRNA CTD PMID:17290305 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS multiple interactions ISO Cycloheximide inhibits the reaction [Dihydrotestosterone results in decreased expression of CHRM1 mRNA] CTD PMID:17624924 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression EXP Cycloheximide results in increased expression of CISH mRNA CTD PMID:23237828 NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of CITED2 mRNA CTD PMID:19684285 NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422
JBrowse link
G Ckb creatine kinase, brain multiple interactions ISO Cycloheximide inhibits the reaction [Estradiol results in increased expression of CKB protein]; Cycloheximide inhibits the reaction [Methoxychlor results in increased expression of CKB protein] CTD PMID:7839363 NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772
JBrowse link
G Clcn3 chloride channel, voltage-sensitive 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CLCN3 mRNA CTD PMID:19684285 NCBI chr 8:61,363,423...61,436,351
Ensembl chr 8:61,363,423...61,436,334
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [Dronabinol results in increased expression of CNR1 mRNA]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]
Cycloheximide results in decreased expression of and affects the localization of CNR1 protein
CTD PMID:17041005 PMID:22258905 PMID:27513693 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Col10a1 collagen, type X, alpha 1 multiple interactions EXP Cycloheximide inhibits the reaction [Tretinoin results in increased expression of COL10A1 mRNA] CTD PMID:16350840 NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions EXP Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA]; Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA]; Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA] CTD PMID:15962303 PMID:17203194 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Cycloheximide inhibits the reaction [Thapsigargin affects the localization of CREB1 mRNA] CTD PMID:29576526 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A affects response to substance ISO CRPPA gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr12:36,430,334...36,739,502
Ensembl chr12:36,431,449...36,739,502
JBrowse link
G Cryl1 crystallin, lambda 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CRYL1 mRNA CTD PMID:19684285 NCBI chr14:57,512,491...57,635,940
Ensembl chr14:57,512,450...57,635,986
JBrowse link
G Csf1 colony stimulating factor 1 (macrophage) multiple interactions EXP Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc results in increased expression of CSF1 mRNA] CTD PMID:12112025 PMID:17295206 PMID:18636177 NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) multiple interactions ISO Cycloheximide inhibits the reaction [IL1B results in increased secretion of CSF2 protein]; Cycloheximide inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Cycloheximide inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein] CTD PMID:9606035 PMID:10645887 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csnk1d casein kinase 1, delta multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CSNK1D mRNA] CTD PMID:11007951 NCBI chr11:120,848,535...120,882,180
Ensembl chr11:120,849,816...120,882,156
JBrowse link
G Csnk2b casein kinase 2, beta polypeptide decreases degradation
multiple interactions
EXP Cycloheximide results in decreased degradation of CSNK2B protein
Diethylhexyl Phthalate inhibits the reaction [Cycloheximide results in decreased degradation of CSNK2B protein]; TNFAIP1 protein inhibits the reaction [Cycloheximide results in decreased degradation of CSNK2B protein]
CTD PMID:37302538 NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
EXP Cycloheximide results in decreased expression of CTNNB1 protein
Phenobarbital affects the reaction [Cycloheximide results in decreased expression of CTNNB1 protein]
CTD PMID:27693619 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Ctsb cathepsin B multiple interactions ISO Cycloheximide inhibits the reaction [Azithromycin results in increased activity of CTSB protein] CTD PMID:8830663 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372
JBrowse link
G Cul2 cullin 2 multiple interactions ISO CUL2 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein] CTD PMID:31645432 NCBI chr18:3,382,970...3,436,700
Ensembl chr18:3,382,988...3,436,377
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO Cycloheximide inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]] CTD PMID:22121136 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CXCL8 mRNA
[TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein; Cycloheximide inhibits the reaction [cadmium sulfate results in increased secretion of CXCL8 protein]; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of IL1B protein]; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of IL6 protein]; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of TNF protein]; Cycloheximide inhibits the reaction [CXCL8 protein results in increased expression of CCND1 protein]; Cycloheximide inhibits the reaction [deoxynivalenol results in increased expression of CXCL8 protein]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Zinc deficiency results in decreased expression of CXCL8 protein]]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]]
CTD PMID:8071060 PMID:12812920 PMID:17606477 PMID:18308354 PMID:21146893 More... NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYCS mRNA] CTD PMID:11007951 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO Cycloheximide results in decreased expression of CYP11A1 protein CTD PMID:21126571 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
decreases expression
ISO Cycloheximide results in decreased activity of CYP19A1 protein
Cycloheximide results in decreased expression of CYP19A1 protein
CTD PMID:16480277 PMID:21126571 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects expression
increases expression
multiple interactions
ISO
EXP
Cycloheximide affects the expression of CYP1A1 mRNA
Cycloheximide results in increased expression of CYP1A1 mRNA
3'-methoxy-4'-nitroflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; [Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein; [Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein; [Cycloheximide co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1A1 mRNA; alpha-naphthoflavone inhibits the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; Benzimidazoles promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein]; beta-Naphthoflavone promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Cycloheximide promotes the reaction [[Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Skatole results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
[Cycloheximide results in increased activity of [AHR protein binds to ARNT protein]] which results in increased expression of CYP1A1 mRNA; [Piperonyl Butoxide co-treated with Cycloheximide] results in increased expression of CYP1A1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; Cycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Lead results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Semaxinib results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Dactinomycin promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]
CTD PMID:1321828 PMID:1849469 PMID:1934297 PMID:2985607 PMID:8647108 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Cycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:1849469 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of CYP1B1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA; Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]
Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]
CTD PMID:9145908 PMID:19684285 PMID:21867498 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO alpha-naphthoflavone inhibits the reaction [Cycloheximide promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA]]; Cycloheximide inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:19244278 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 increases expression
multiple interactions
decreases expression
EXP
ISO
Cycloheximide results in increased expression of CYP2A5 mRNA
Bilirubin inhibits the reaction [Cycloheximide results in decreased expression of CYP2A6 protein]
CTD PMID:9007836 PMID:22465937 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases degradation
ISO (4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]; Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]
Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]; Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein]
CTD PMID:1968335 PMID:8531136 PMID:9143349 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 multiple interactions ISO Cycloheximide inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
JBrowse link
G Dag1 dystroglycan 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DAG1 mRNA] CTD PMID:11007951 NCBI chr 9:108,082,060...108,141,176
Ensembl chr 9:108,081,833...108,141,157
JBrowse link
G Dcn decorin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DCN mRNA] CTD PMID:11007951 NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO Cycloheximide inhibits the reaction [plumbagin results in increased expression of DDIT3 protein] CTD PMID:31276663 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of DDIT4 protein
[EGF protein co-treated with Cycloheximide] results in increased expression of DDIT4 protein
CTD PMID:22689575 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Deaf1 DEAF1, transcription factor multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of DEAF1 mRNA CTD PMID:19684285 NCBI chr 7:140,877,089...140,918,758
Ensembl chr 7:140,877,093...140,907,603
JBrowse link
G Degs1 delta 4-desaturase, sphingolipid 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DEGS1 mRNA] CTD PMID:11007951 NCBI chr 1:182,103,529...182,110,366
Ensembl chr 1:182,103,337...182,110,369
JBrowse link
G Dio2 deiodinase, iodothyronine, type II multiple interactions
decreases activity
ISO [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [2,2',4,4',5-brominated diphenyl ether metabolite results in decreased activity of DIO2 protein]; [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased activity of DIO2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]]; lactacystin inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein] CTD PMID:11425850 PMID:26004626 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
G Dio3 deiodinase, iodothyronine type III multiple interactions ISO Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] CTD PMID:18420745 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of DNAJB5 mRNA] CTD PMID:11007951 NCBI chr 4:42,949,866...42,959,425
Ensembl chr 4:42,949,814...42,959,425
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 increases expression EXP Cycloheximide results in increased expression of DNASE1L3 protein CTD PMID:15118903 NCBI chr14:14,475,014...14,504,586
Ensembl chr14:14,475,200...14,505,240
JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions
ISO Cycloheximide results in increased expression of DNM1L mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of DNM1L mRNA
CTD PMID:19684285 NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823
JBrowse link
G Dnmt3a DNA methyltransferase 3A multiple interactions ISO [Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A mRNA; [Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A protein CTD PMID:19833194 NCBI chr12:3,851,559...3,964,442
Ensembl chr12:3,856,007...3,964,443
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Cycloheximide co-treated with EDN1 protein] results in increased expression of ADRB2 mRNA CTD PMID:22483689 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Ednra endothelin receptor type A multiple interactions ISO [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Cycloheximide] results in decreased expression of EDNRA protein; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRA mRNA]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRA protein] CTD PMID:20561571 NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093
JBrowse link
G Ednrb endothelin receptor type B multiple interactions ISO Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRB mRNA]; Cycloheximide inhibits the reaction [Particulate Matter results in increased expression of EDNRB protein]; Cycloheximide inhibits the reaction [Smoke analog results in increased expression of EDNRB protein] CTD PMID:20561571 PMID:20716444 NCBI chr14:104,052,055...104,081,764
Ensembl chr14:104,052,061...104,081,838
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [EGF protein co-treated with Cycloheximide] results in increased expression of DDIT4 protein; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Arginine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Isoleucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Leucine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Lysine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Methionine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Ornithine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Phenylalanine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Tyrosine]; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Valine]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]]; Cycloheximide promotes the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA] CTD PMID:12632255 PMID:22689575 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO Cycloheximide results in increased expression of EGFR mRNA
Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]
Cycloheximide promotes the reaction [Arsenic Trioxide results in decreased expression of EGFR protein]
CTD PMID:15228094 PMID:26368632 PMID:30237564 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO Cycloheximide inhibits the reaction [resveratrol results in increased expression of EGR1 mRNA] CTD PMID:12690110 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 increases expression ISO Cycloheximide results in increased expression of EGR2 mRNA CTD PMID:19350554 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions ISO Cycloheximide inhibits the reaction [epimedokoreanin B results in increased phosphorylation of EIF2A protein]; Cycloheximide inhibits the reaction [Orlistat results in increased phosphorylation of EIF2A protein] CTD PMID:17283163 PMID:36027945 NCBI chr 3:58,433,252...58,464,922
Ensembl chr 3:58,433,242...58,464,922
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Cycloheximide inhibits the reaction [dimethylarsinous acid results in increased phosphorylation of EIF2AK3 protein]
Cycloheximide inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [1,12-benzoperylene results in increased expression of EIF2AK3 mRNA]]
CTD PMID:22425709 PMID:35182551 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases expression
multiple interactions
increases phosphorylation
ISO
EXP
Cycloheximide results in increased expression of EIF2S1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of EIF2S1 mRNA
Cycloheximide results in increased phosphorylation of EIF2S1 protein
CTD PMID:19684285 PMID:24315374 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of CCND1 protein]]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of ELAVL1 protein]]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of MCL1 protein]]
Cycloheximide inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]
CTD PMID:22689575 PMID:25923732 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]; Cycloheximide promotes the reaction [EIF4EBP1 protein binds to EIF4G1 protein] CTD PMID:22689575 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4, gamma 1 multiple interactions ISO Cycloheximide promotes the reaction [EIF4EBP1 protein binds to EIF4G1 protein] CTD PMID:22689575 NCBI chr16:20,491,457...20,511,633
Ensembl chr16:20,487,063...20,511,634
JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of EIF4G3 mRNA] CTD PMID:11007951 NCBI chr 4:137,719,090...137,934,397
Ensembl chr 4:137,720,333...137,935,819
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of EIF5 mRNA CTD PMID:19684285 NCBI chr12:111,504,535...111,513,187
Ensembl chr12:111,504,450...111,513,186
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of ELAVL1 protein]] CTD PMID:25923732 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413
JBrowse link
G Elf4 E74 like ETS transcription factor 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ELF4 mRNA] CTD PMID:11007951 NCBI chr  X:47,499,926...47,552,009
Ensembl chr  X:47,499,923...47,552,009
JBrowse link
G Elk1 ELK1, member of ETS oncogene family increases expression
multiple interactions
ISO Cycloheximide results in increased expression of ELK1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ELK1 mRNA
CTD PMID:19684285 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847
JBrowse link
G Eln elastin multiple interactions ISO Cycloheximide inhibits the reaction [Okadaic Acid results in decreased expression of ELN mRNA] CTD PMID:8997264 NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 decreases expression
multiple interactions
EXP Cycloheximide results in decreased expression of ELOVL3 mRNA
Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of ELOVL3 mRNA]
CTD PMID:17726147 NCBI chr19:46,120,336...46,124,133
Ensembl chr19:46,120,336...46,124,133
JBrowse link
G Enc1 ectodermal-neural cortex 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of ENC1 mRNA CTD PMID:19684285 NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542
JBrowse link
G Endog endonuclease G multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ENDOG mRNA] CTD PMID:11007951 NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of EPAS1 protein]; MALAT1 mRNA inhibits the reaction [Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of EPAS1 protein]]
Cycloheximide results in decreased expression of EPAS1 protein
CTD PMID:23958427 PMID:26735578 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Epo erythropoietin multiple interactions EXP Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA] CTD PMID:10756076 NCBI chr 5:137,481,282...137,484,078
Ensembl chr 5:137,481,282...137,531,504
JBrowse link
G Epyc epiphycan multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EPYC mRNA] CTD PMID:11007951 NCBI chr10:97,479,930...97,517,770
Ensembl chr10:97,479,930...97,518,316
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases expression
increases degradation
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of ERBB2 mRNA; Curcumin analog promotes the reaction [Cycloheximide results in increased degradation of ERBB2 protein]; PA2G4 protein promotes the reaction [Cycloheximide results in decreased expression of ERBB2 protein]
Cycloheximide results in decreased expression of ERBB2 mRNA; Cycloheximide results in decreased expression of ERBB2 protein
CTD PMID:15072547 PMID:15228094 PMID:20379846 PMID:25866362 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases expression ISO Cycloheximide results in decreased expression of ERBB3 mRNA CTD PMID:15228094 NCBI chr10:128,403,392...128,425,504
Ensembl chr10:128,403,392...128,425,521
JBrowse link
G Ereg epiregulin increases expression ISO Cycloheximide results in increased expression of EREG mRNA CTD PMID:15228094 NCBI chr 5:91,222,476...91,241,508
Ensembl chr 5:91,222,481...91,241,505
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions ISO Cycloheximide inhibits the reaction [Butyric Acid results in increased expression of ERN1 protein] CTD PMID:26784903 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions
decreases expression
ISO bisphenol A promotes the reaction [Cycloheximide results in decreased expression of ESR1 protein]; Estradiol promotes the reaction [Cycloheximide results in decreased expression of ESR1 protein]; naringenin inhibits the reaction [Cycloheximide results in decreased expression of ESR1 protein] CTD PMID:24586459 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Cycloheximide promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]] CTD PMID:15207704 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
G Esrra estrogen related receptor, alpha decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of ESRRA protein
HDAC6 protein inhibits the reaction [Cycloheximide results in decreased expression of ESRRA protein]
CTD PMID:34524571 NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208
JBrowse link
G Ext2 exostosin glycosyltransferase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of EXT2 mRNA] CTD PMID:11007951 NCBI chr 2:93,525,978...93,652,913
Ensembl chr 2:93,491,373...93,652,913
JBrowse link
G F12 coagulation factor XII (Hageman factor) multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of F12 mRNA] CTD PMID:11007951 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606
JBrowse link
G F2 coagulation factor II multiple interactions ISO Cycloheximide inhibits the reaction [Simvastatin results in decreased activity of F2 protein] CTD PMID:14630613 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759
JBrowse link
G F3 coagulation factor III multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in decreased expression of F3 mRNA] CTD PMID:11876987 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases response to substance
ISO
EXP
Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP3 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP7 protein]; Cycloheximide promotes the reaction [FAS protein results in increased activity of CASP8 protein]
Cycloheximide results in increased susceptibility to FAS protein
CTD PMID:8932996 PMID:12760867 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FASLG mRNA]
[Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A mRNA; [Cycloheximide co-treated with FASLG protein] results in decreased expression of DNMT3A protein
CTD PMID:11007951 PMID:19833194 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO Cycloheximide inhibits the reaction [Calcitriol results in decreased expression of FASN mRNA] CTD PMID:12798352 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fbl fibrillarin multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FBL mRNA CTD PMID:19684285 NCBI chr 7:27,868,293...27,878,701
Ensembl chr 7:27,869,135...27,878,694
JBrowse link
G Fbxw7 F-box and WD-40 domain protein 7 multiple interactions ISO
EXP
Cycloheximide promotes the reaction [FBXW7 protein binds to and results in decreased expression of RICTOR protein]
FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]
CTD PMID:24457827 PMID:25897075 NCBI chr 3:84,721,901...84,886,505
Ensembl chr 3:84,722,575...84,886,505
JBrowse link
G Fga fibrinogen alpha chain decreases expression ISO Cycloheximide results in decreased expression of FGA protein CTD PMID:444225 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain decreases expression ISO Cycloheximide results in decreased expression of FGB protein CTD PMID:444225 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO Cycloheximide inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Cycloheximide promotes the reaction [FGF2 protein results in increased expression of SERPINE1 mRNA] CTD PMID:9798919 PMID:15654655 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Triiodothyronine results in increased expression of FGFR1 mRNA] CTD PMID:12805413 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgl2 fibrinogen-like protein 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FGL2 mRNA] CTD PMID:11007951 NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372
JBrowse link
G Fhit fragile histidine triad gene multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FHIT mRNA CTD PMID:19684285 NCBI chr14:11,307,718...12,919,681
Ensembl chr14:11,307,738...12,919,681
JBrowse link
G Fhl1 four and a half LIM domains 1 multiple interactions ISO Cycloheximide promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA] CTD PMID:17161435 NCBI chr  X:55,776,569...55,838,704
Ensembl chr  X:55,777,147...55,838,706
JBrowse link
G Flt3 FMS-like tyrosine kinase 3 decreases expression ISO Cycloheximide results in decreased expression of FLT3 protein mutant form CTD PMID:32284743 NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
JBrowse link
G Fmo3 flavin containing monooxygenase 3 increases expression EXP Cycloheximide results in increased expression of FMO3 mRNA CTD PMID:20570689 NCBI chr 1:162,781,368...162,812,097
Ensembl chr 1:162,781,369...162,812,097
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of FMR1 mRNA CTD PMID:19684285 NCBI chr  X:67,722,144...67,761,569
Ensembl chr  X:67,722,147...67,761,569
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
ISO
EXP
Cycloheximide inhibits the reaction [Estradiol results in increased expression of FOS protein]; Cycloheximide inhibits the reaction [Genistein results in increased expression of FOS protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of FOS protein]; Cycloheximide promotes the reaction [Cadmium Chloride results in increased expression of FOS mRNA]
Cycloheximide results in increased expression of FOS mRNA
[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA; Cadmium Chloride promotes the reaction [Cycloheximide results in increased expression of FOS mRNA]; Cycloheximide inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS protein]; Cycloheximide promotes the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA]; Cycloheximide promotes the reaction [Cadmium Chloride results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA]
Cycloheximide inhibits the reaction [NGF protein results in increased expression of FOS protein]
CTD PMID:1696944 PMID:9094091 PMID:9417049 PMID:9650640 PMID:12632255 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Frk fyn-related kinase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FRK mRNA] CTD PMID:11007951 NCBI chr10:34,359,396...34,487,530
Ensembl chr10:34,359,395...34,487,274
JBrowse link
G Fst follistatin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FST mRNA] CTD PMID:11007951 NCBI chr13:114,588,798...114,595,522
Ensembl chr13:114,588,826...114,595,487
JBrowse link
G Fut4 fucosyltransferase 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of FUT4 mRNA] CTD PMID:11007951 NCBI chr 9:14,659,755...14,663,418
Ensembl chr 9:14,659,616...14,663,689
JBrowse link
G Fzd7 frizzled class receptor 7 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of FZD7 mRNA] CTD PMID:11007951 NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions ISO Cycloheximide inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of GALNT1 mRNA CTD PMID:19684285 NCBI chr18:24,338,401...24,419,873
Ensembl chr18:24,338,401...24,419,875
JBrowse link
G Gas1 growth arrest specific 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GAS1 mRNA] CTD PMID:11007951 NCBI chr13:60,322,219...60,325,179
Ensembl chr13:60,322,219...60,325,179
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP
ISO
Cycloheximide inhibits the reaction [arsenite results in increased activity of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of GCLC mRNA]; Cycloheximide inhibits the reaction [diphenylarsinic acid results in increased expression of GCLC protein]
Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]
CTD PMID:17628625 PMID:19328227 PMID:24437944 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions EXP Cycloheximide inhibits the reaction [arsenite results in increased activity of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of [GCLC protein binds to GCLM protein]]; Cycloheximide inhibits the reaction [arsenite results in increased expression of GCLM mRNA] CTD PMID:19328227 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA]; Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 protein]; Cycloheximide inhibits the reaction [troglitazone results in increased expression of GDF15 mRNA] CTD PMID:14662774 PMID:18801729 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
decreases expression
ISO 9,10-Dimethyl-1,2-benzanthracene promotes the reaction [Cycloheximide results in decreased expression of GJA1 protein]; Cycloheximide promotes the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein] CTD PMID:34283317 PMID:36863560 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609
JBrowse link
G Gpaa1 GPI anchor attachment protein 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of GPAA1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of GPAA1 mRNA
CTD PMID:19684285 NCBI chr15:76,215,494...76,219,099
Ensembl chr15:76,215,431...76,219,107
JBrowse link
G Gpr37 G protein-coupled receptor 37 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GPR37 mRNA] CTD PMID:11007951 NCBI chr 6:25,668,522...25,689,979
Ensembl chr 6:25,665,877...25,690,728
JBrowse link
G Grm5 glutamate receptor, metabotropic 5 multiple interactions ISO Cycloheximide inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 mRNA]; Cycloheximide inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 protein] CTD PMID:11665859 NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115
JBrowse link
G Grn granulin multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of GRN mRNA CTD PMID:19684285 NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of GSK3B mRNA] CTD PMID:11007951 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Gsta3 glutathione S-transferase, alpha 3 decreases expression
multiple interactions
EXP Cycloheximide results in decreased expression of GSTA1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]]; Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]; Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]; Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]
CTD PMID:16243960 NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Cycloheximide results in increased expression of HBEGF mRNA CTD PMID:15228094 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hdac6 histone deacetylase 6 multiple interactions ISO HDAC6 protein inhibits the reaction [Cycloheximide results in decreased expression of ESRRA protein] CTD PMID:34524571 NCBI chr  X:7,796,355...7,814,284
Ensembl chr  X:7,796,359...7,814,128
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions
increases degradation
decreases expression
ISO
EXP
[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein; [Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein; [Cycloheximide co-treated with Oxygen deficiency] affects the expression of HIF1A protein; [Oxygen deficiency co-treated with Cycloheximide] affects the expression of HIF1A protein; Cycloheximide affects the reaction [[Apigenin co-treated with Oxygen deficiency] affects the expression of HIF1A protein]; Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [bruceine D inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]; Cycloheximide inhibits the reaction [TAK-243 results in increased sumoylation of HIF1A protein]; Cycloheximide inhibits the reaction [zinc chloride results in increased expression of HIF1A protein alternative form]; Cycloheximide promotes the reaction [Cobalt results in increased expression of HIF1A protein]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of HIF1A protein]; Cycloheximide promotes the reaction [sodium arsenite inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; genipin affects the reaction [[Oxygen deficiency co-treated with Cycloheximide] affects the expression of HIF1A protein]; L-4F peptide promotes the reaction [[Cycloheximide co-treated with cobaltous chloride] results in decreased expression of HIF1A protein]; L-4F peptide promotes the reaction [[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose co-treated with Cycloheximide] results in decreased expression of HIF1A protein]; scutellarin promotes the reaction [Cycloheximide inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; sodium arsenite inhibits the reaction [Cycloheximide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]
Cycloheximide results in increased degradation of HIF1A protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Cycloheximide inhibits the reaction [Polystyrenes analog results in increased expression of HIF1A protein]
Cycloheximide results in decreased expression of HIF1A
Cycloheximide results in decreased expression of HIF1A protein
Cycloheximide promotes the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]
CTD PMID:11641398 PMID:11739637 PMID:19958256 PMID:20524035 PMID:22537771 More... NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
ISO
EXP
Cycloheximide inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [Plant Extracts results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Resveratrol results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [Resveratrol results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 protein]; Cycloheximide results in decreased susceptibility to [surfactin peptide results in increased expression of HMOX1 protein]; USP7 protein inhibits the reaction [Cycloheximide results in decreased expression of HMOX1 protein]; USP7 protein mutant form affects the reaction [Cycloheximide results in decreased expression of HMOX1 protein]
Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [fisetin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Triterpenes analog results in increased expression of HMOX1 protein]
Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]; Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [resveratrol results in increased expression of HMOX1 protein]; Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]
CTD PMID:9747510 PMID:12441344 PMID:12472888 PMID:15118350 PMID:15588712 More... NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 increases expression ISO Cycloheximide results in increased expression of HNRNPH2 mRNA CTD PMID:19684285 NCBI chr  X:133,501,928...133,507,809
Ensembl chr  X:133,501,928...133,507,809
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO Cycloheximide inhibits the reaction [Glycine results in increased expression of HNRNPK protein] CTD PMID:24990929 NCBI chr13:58,538,946...58,551,157
Ensembl chr13:58,538,956...58,551,157
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions ISO Cycloheximide promotes the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Cycloheximide promotes the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Cycloheximide promotes the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA] CTD PMID:31927052 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
JBrowse link
G Hsf1 heat shock factor 1 decreases activity ISO Cycloheximide results in decreased activity of HSF1 protein CTD PMID:34170685 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions ISO Cycloheximide inhibits the reaction [GIF 0010 results in increased expression of HSPA5 mRNA]; Cycloheximide inhibits the reaction [lead acetate results in increased expression of HSPA5 protein]; Cycloheximide inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 protein]
Cycloheximide inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Cycloheximide inhibits the reaction [Butyric Acid results in increased expression of HSPA5 protein]; Cycloheximide inhibits the reaction [plumbagin results in increased expression of HSPA5 protein]
CTD PMID:9742210 PMID:17915553 PMID:26784903 PMID:31276663 PMID:34560123 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HTATIP2 mRNA] CTD PMID:11007951 NCBI chr 7:49,408,761...49,423,748
Ensembl chr 7:49,408,863...49,423,723
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]
Cycloheximide results in decreased expression of ICAM1 protein
CTD PMID:16087364 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [afimoxifene co-treated with Cycloheximide] results in increased expression of IER3 mRNA CTD PMID:16849584 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Cycloheximide co-treated with IFNG protein] results in increased expression of PLAUR mRNA; Cycloheximide inhibits the reaction [IFNG protein results in increased expression of ICAM1 protein]; Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein] CTD PMID:12070711 PMID:16087364 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ift27 intraflagellar transport 27 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of IFT27 mRNA] CTD PMID:11007951 NCBI chr15:78,043,660...78,058,281
Ensembl chr15:78,043,663...78,058,307
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP
ISO
Cycloheximide inhibits the reaction [IGF1 protein affects the metabolism of 1,2-diacylglycerol]
IGF1 protein inhibits the reaction [Cycloheximide results in decreased expression of CDKN1A protein]
CTD PMID:2120207 PMID:26687534 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions ISO Cycloheximide promotes the reaction [Berberine results in decreased expression of IGF2BP3 protein] CTD PMID:36822301 NCBI chr 6:49,062,152...49,200,225
Ensembl chr 6:49,062,157...49,191,891
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of IGFBP4 mRNA
[Cycloheximide co-treated with Estradiol] results in increased expression of IGFBP4 mRNA
CTD PMID:15072547 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
decreases response to substance
EXP
ISO
Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
Cycloheximide results in increased expression of IL10 mRNA
IL10 protein results in decreased susceptibility to Cycloheximide
CTD PMID:19395591 PMID:22183712 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il17a interleukin 17A multiple interactions EXP Cycloheximide inhibits the reaction [Glucose results in increased secretion of IL17A protein] CTD PMID:18310510 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Cycloheximide inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1A mRNA
Cycloheximide results in increased expression of IL1A mRNA
CTD PMID:19684285 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of IL1B mRNA; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of IL1B protein]; Cycloheximide inhibits the reaction [Dinoprostone promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Cycloheximide inhibits the reaction [IL1B results in increased secretion of CSF2 protein]; Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]
Cycloheximide results in increased expression of IL1B mRNA
Cycloheximide promotes the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
CTD PMID:8071060 PMID:9606035 PMID:11112151 PMID:11286988 PMID:19684285 More... NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il5 interleukin 5 decreases expression
multiple interactions
EXP Cycloheximide results in decreased expression of IL5 protein
T0901317 inhibits the reaction [Cycloheximide results in decreased expression of IL5 protein]
CTD PMID:23150660 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 multiple interactions
increases secretion
increases expression
decreases secretion
ISO
EXP
Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of IL6 protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]]
Cycloheximide results in decreased secretion of IL6 protein
CTD PMID:8071060 PMID:11216681 PMID:12185005 PMID:21146893 PMID:24771768 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IL6ST mRNA] CTD PMID:11007951 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Ins1 insulin I multiple interactions ISO Cycloheximide inhibits the reaction [apigenin-6-C-(2''-O-rhamnopyranosyl)-fucopyranoside promotes the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:19070612 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Ins2 insulin II multiple interactions ISO [Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein; L-4F peptide promotes the reaction [[Cycloheximide co-treated with INS protein] results in decreased expression of HIF1A protein] CTD PMID:22537771 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IQGAP1 mRNA] CTD PMID:11007951 NCBI chr 7:80,361,331...80,453,288
Ensembl chr 7:80,361,331...80,475,722
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of IRS1 mRNA
[Cycloheximide co-treated with Estradiol] results in increased expression of IRS1 mRNA
CTD PMID:15072547 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Itgb3 integrin beta 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB3 mRNA] CTD PMID:11007951 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Itgb6 integrin beta 6 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITGB6 mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA] CTD PMID:11007951 PMID:21303922 NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987
JBrowse link
G Itpk1 inositol 1,3,4-triphosphate 5/6 kinase multiple interactions ISO ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]; ITPK1 mutant form results in increased susceptibility to [Cycloheximide co-treated with TNF protein] CTD PMID:12925536 NCBI chr12:102,534,842...102,671,128
Ensembl chr12:102,534,841...102,671,189
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Ethanol results in increased expression of ITPR1 mRNA]; Cycloheximide inhibits the reaction [linsidomine results in increased expression of ITPR1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ITPR1 mRNA] CTD PMID:11007951 PMID:17241155 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070
JBrowse link
G Ivns1abp influenza virus NS1A binding protein multiple interactions EXP Cycloheximide inhibits the reaction [Doxorubicin results in decreased expression of IVNS1ABP mRNA] CTD PMID:17016628 NCBI chr 1:151,220,237...151,240,196
Ensembl chr 1:151,220,228...151,240,173
JBrowse link
G Jun jun proto-oncogene increases stability
multiple interactions
increases phosphorylation
ISO
EXP
Cycloheximide results in increased stability of JUN protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein]
Cycloheximide promotes the reaction [Cadmium results in increased expression of JUN mRNA]
Cycloheximide results in increased phosphorylation of JUN protein
CTD PMID:1696944 PMID:9751194 PMID:12169099 PMID:23593480 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KANK1 mRNA CTD PMID:19684285 NCBI chr19:25,214,146...25,411,861
Ensembl chr19:25,214,339...25,411,860
JBrowse link
G Kng1 kininogen 1 multiple interactions ISO Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK1 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK3 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of PTGS2 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased secretion of TAC1 protein] CTD PMID:16696851 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of KRAS mRNA] CTD PMID:11007951 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 affects response to substance ISO KREMEN1 gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr11:5,141,551...5,212,220
Ensembl chr11:5,141,552...5,211,558
JBrowse link
G Krt13 keratin 13 multiple interactions ISO [afimoxifene co-treated with Cycloheximide] results in increased expression of KRT13 mRNA CTD PMID:16849584 NCBI chr11:100,008,153...100,012,392
Ensembl chr11:100,008,153...100,012,392
JBrowse link
G Krtcap2 keratinocyte associated protein 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of KRTCAP2 mRNA CTD PMID:19684285 NCBI chr 3:89,153,201...89,157,036
Ensembl chr 3:89,153,273...89,157,213
JBrowse link
G Lck lymphocyte protein tyrosine kinase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LCK mRNA] CTD PMID:11007951 NCBI chr 4:129,442,142...129,467,415
Ensembl chr 4:129,442,137...129,467,434
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [Quercetin results in increased expression of LDLR protein]
Cycloheximide results in decreased expression of LDLR protein
CTD PMID:22388943 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin multiple interactions EXP LEP protein inhibits the reaction [Cycloheximide results in decreased expression of LEPR protein] CTD PMID:31199479 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lepr leptin receptor multiple interactions
decreases expression
EXP LEP protein inhibits the reaction [Cycloheximide results in decreased expression of LEPR protein] CTD PMID:31199479 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549
JBrowse link
G Lgals3 lectin, galactose binding, soluble 3 multiple interactions ISO Cycloheximide inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of LGALS3 protein] CTD PMID:21821001 NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617
JBrowse link
G Lhb luteinizing hormone beta multiple interactions ISO Cycloheximide promotes the reaction [LHB protein results in increased expression of NR4A1 mRNA] CTD PMID:11416027 NCBI chr 7:45,070,370...45,071,278
Ensembl chr 7:45,070,244...45,071,321
JBrowse link
G Lmo7 LIM domain only 7 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LMO7 mRNA] CTD PMID:11007951 NCBI chr14:101,967,353...102,172,144
Ensembl chr14:101,967,386...102,172,146
JBrowse link
G Lpxn leupaxin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of LPXN mRNA] CTD PMID:11007951 NCBI chr19:12,773,251...12,811,177
Ensembl chr19:12,773,557...12,811,171
JBrowse link
G Maf1 MAF1 homolog, negative regulator of RNA polymerase III increases degradation
multiple interactions
ISO Cycloheximide results in increased degradation of MAF1 protein
Bortezomib inhibits the reaction [Cycloheximide results in increased degradation of MAF1 protein]; CUL2 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein]; Cycloheximide inhibits the reaction [Sirolimus results in increased expression of MAF1 protein]; PSMD1 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein]
CTD PMID:31645432 NCBI chr15:76,235,494...76,238,578
Ensembl chr15:76,235,494...76,238,580
JBrowse link
G Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) multiple interactions ISO MALAT1 mRNA inhibits the reaction [Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of EPAS1 protein]]; sodium arsenite inhibits the reaction [Cycloheximide results in decreased expression of MALAT1 protein] CTD PMID:26735578 NCBI chr19:5,845,718...5,852,700
Ensembl chr19:5,845,717...5,852,706
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions
increases activity
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cycloheximide results in increased expression of MAP2K1 mRNA]
Cycloheximide results in increased activity of MAP2K1 protein
CTD PMID:23237828 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Cycloheximide results in increased phosphorylation of MAPK1 protein
TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein]
Cycloheximide inhibits the reaction [Cyclosporine results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein]]
Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK1 protein]; Cycloheximide promotes the reaction [[sodium arsenite co-treated with Hydrogen Peroxide] results in increased phosphorylation of MAPK1 protein]
CTD PMID:12472888 PMID:15087236 PMID:16696851 PMID:22155090 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein] CTD PMID:17507666 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
Cycloheximide results in increased phosphorylation of MAPK3 protein
TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein]
Cycloheximide inhibits the reaction [Cyclosporine results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein]]
Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of MAPK3 protein]; Cycloheximide promotes the reaction [sodium arsenite promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]]
CTD PMID:12472888 PMID:15087236 PMID:16696851 PMID:22155090 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MAPK7 mRNA; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MAPK7 mRNA]
Cycloheximide results in increased expression of MAPK7 mRNA
CTD PMID:11007951 PMID:19684285 NCBI chr11:61,379,638...61,385,101
Ensembl chr11:61,379,638...61,385,232
JBrowse link
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 affects response to substance ISO MAPKAPK3 gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 9:107,132,125...107,167,082
Ensembl chr 9:107,132,126...107,167,076
JBrowse link
G Mbp myelin basic protein affects expression ISO Cycloheximide affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with MCL1] results in increased susceptibility to ABT-737; [Resveratrol co-treated with Clofarabine co-treated with Cycloheximide] results in decreased expression of MCL1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MCL1 protein]; Cycloheximide inhibits the reaction [EIF4E protein modified form inhibits the reaction [sodium arsenite results in decreased expression of MCL1 protein]]; Cycloheximide promotes the reaction [[WEHI-539 co-treated with venetoclax] results in decreased expression of MCL1 protein] CTD PMID:14982947 PMID:21880625 PMID:24924397 PMID:25408576 PMID:25923732 More... NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mdk midkine multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of MDK mRNA] CTD PMID:11007951 NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642
JBrowse link
G Mir21a microRNA 21a increases expression
multiple interactions
ISO Cycloheximide results in increased expression of MIR21 mRNA
Cycloheximide inhibits the reaction [Dihydrotestosterone results in increased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [Estradiol results in decreased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA]; Cycloheximide inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA]
CTD PMID:19264808 PMID:23052036 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mir22hg Mir22 host gene (non-protein coding) multiple interactions ISO Cycloheximide results in increased stability of and results in increased expression of MIR22HG mRNA CTD PMID:24036268 NCBI chr11:75,352,365...75,357,516
Ensembl chr11:75,352,365...75,357,502
JBrowse link
G Mitf melanogenesis associated transcription factor multiple interactions ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Cycloheximide co-treated with 4-(1-phenylethyl)-1,3-benzenediol] results in increased degradation of MITF protein]; [Cycloheximide co-treated with 4-(1-phenylethyl)-1,3-benzenediol] results in increased degradation of MITF protein CTD PMID:30849679 NCBI chr 6:97,783,966...97,998,321
Ensembl chr 6:97,784,013...97,998,310
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions
ISO
EXP
Cycloheximide results in increased expression of MMP13 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MMP13 mRNA
Cycloheximide inhibits the reaction [Tretinoin results in increased expression of MMP13 mRNA]
CTD PMID:16350840 PMID:19684285 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) multiple interactions ISO Cycloheximide inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MMP1 mRNA] CTD PMID:15075337 PMID:19136476 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of MMP2 mRNA] CTD PMID:26621329 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MNX1 mRNA] CTD PMID:11007951 NCBI chr 5:29,678,821...29,683,468
Ensembl chr 5:29,678,032...29,683,468
JBrowse link
G Mpg N-methylpurine-DNA glycosylase multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MPG mRNA] CTD PMID:11007951 NCBI chr11:32,176,505...32,182,702
Ensembl chr11:32,176,505...32,182,700
JBrowse link
G Mrps7 mitchondrial ribosomal protein S7 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of MRPS7 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of MRPS7 mRNA
CTD PMID:19684285 NCBI chr11:115,494,966...115,498,862
Ensembl chr11:115,494,751...115,498,862
JBrowse link
G Msh3 mutS homolog 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MSH3 mRNA] CTD PMID:11007951 NCBI chr13:92,348,387...92,491,515
Ensembl chr13:92,348,380...92,491,511
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:9614211 NCBI chr 8:39,996,284...40,095,790
Ensembl chr 8:40,034,726...40,095,714
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
EXP 2-tert-butylhydroquinone promotes the reaction [Cycloheximide results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]; MTF1 protein affects the reaction [Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [Cycloheximide results in increased expression of MT1 mRNA] CTD PMID:14998373 PMID:19276070 NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955
JBrowse link
G Mtch2 mitochondrial carrier 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MTCH2 mRNA CTD PMID:19684285 NCBI chr 2:90,677,434...90,697,154
Ensembl chr 2:90,677,499...90,697,154
JBrowse link
G Mterf3 mitochondrial transcription termination factor 3 multiple interactions
decreases expression
ISO Ammonium Chloride inhibits the reaction [Cycloheximide results in decreased expression of MTERF3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MTERF3 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [Cycloheximide results in decreased expression of MTERF3 protein]; Chloroquine inhibits the reaction [Cycloheximide results in decreased expression of MTERF3 protein] CTD PMID:35904214 NCBI chr13:67,053,520...67,081,148
Ensembl chr13:67,055,032...67,081,152
JBrowse link
G Mtf1 metal response element binding transcription factor 1 multiple interactions EXP MTF1 protein affects the reaction [Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]]; MTF1 protein affects the reaction [Cycloheximide results in increased expression of MT1 mRNA] CTD PMID:19276070 NCBI chr 4:124,696,342...124,743,593
Ensembl chr 4:124,695,897...124,743,593
JBrowse link
G Mtmr7 myotubularin related protein 7 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of MTMR7 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MTMR7 mRNA
CTD PMID:19684285 NCBI chr 8:41,003,184...41,088,210
Ensembl chr 8:41,004,136...41,087,840
JBrowse link
G Mxd1 MAX dimerization protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MXD1 mRNA] CTD PMID:11007951 NCBI chr 6:86,624,026...86,646,099
Ensembl chr 6:86,624,024...86,646,143
JBrowse link
G Mxd3 Max dimerization protein 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of MXD3 mRNA CTD PMID:19684285 NCBI chr13:55,472,983...55,477,937
Ensembl chr13:55,472,981...55,477,636
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions EXP
ISO
arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein]; FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]; NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]
Cycloheximide promotes the reaction [Cadmium results in increased expression of MYC mRNA]
Cycloheximide inhibits the reaction [TAK-243 results in increased sumoylation of MYC protein]
CTD PMID:1696944 PMID:23593480 PMID:24457827 PMID:31285264 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Mylk myosin, light polypeptide kinase multiple interactions ISO Cycloheximide inhibits the reaction [TNF protein results in increased expression of MYLK protein] CTD PMID:15701621 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Myo1d myosin ID affects response to substance ISO MYO1D gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr11:80,372,945...80,670,881
Ensembl chr11:80,372,952...80,670,851
JBrowse link
G Nbr1 NBR1, autophagy cargo receptor increases expression
multiple interactions
ISO Cycloheximide results in increased expression of NBR1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NBR1 mRNA
CTD PMID:19684285 NCBI chr11:101,442,933...101,472,777
Ensembl chr11:101,442,975...101,472,777
JBrowse link
G Ndrg1 N-myc downstream regulated gene 1 multiple interactions
decreases expression
ISO Chloroquine inhibits the reaction [Cycloheximide results in decreased expression of NDRG1 protein] CTD PMID:28906492 NCBI chr15:66,801,167...66,841,490
Ensembl chr15:66,801,167...66,841,489
JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 decreases expression
multiple interactions
EXP Cycloheximide results in decreased expression of NEDD4 protein
Melatonin promotes the reaction [Cycloheximide results in decreased expression of NEDD4 protein]
CTD PMID:31325559 NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134
JBrowse link
G Nefh neurofilament, heavy polypeptide decreases expression ISO Cycloheximide results in decreased expression of NEFH mRNA CTD PMID:19146868 NCBI chr11:4,888,754...4,898,064
Ensembl chr11:4,888,754...4,898,064
JBrowse link
G Nefl neurofilament, light polypeptide decreases expression ISO Cycloheximide results in decreased expression of NEFL mRNA CTD PMID:19146868 NCBI chr14:68,321,312...68,326,544
Ensembl chr14:68,321,312...68,326,544
JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NEK2 mRNA] CTD PMID:11007951 NCBI chr 1:191,553,622...191,565,161
Ensembl chr 1:191,553,556...191,565,162
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
decreases expression
EXP
ISO
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Cycloheximide] results in increased expression of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]]; Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased activity of NFE2L2 protein]; Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]; Exenatide inhibits the reaction [Cycloheximide results in decreased expression of NFE2L2 protein]
[SB 203580 co-treated with Cycloheximide] inhibits the reaction [Quercetin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]]; Cycloheximide inhibits the reaction [[SB 203580 co-treated with Quercetin] results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [Quercetin results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [SB 203580 affects the reaction [Quercetin affects the localization of NFE2L2 protein]]; Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of NFE2L2 protein]; Cycloheximide inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]
CTD PMID:12441344 PMID:14510636 PMID:15322212 PMID:22019695 PMID:22197970 More... NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 affects localization
increases expression
multiple interactions
ISO
EXP
Cycloheximide affects the localization of NFKB1 protein
Cycloheximide results in increased expression of NFKB1 mRNA
Cycloheximide results in decreased expression of [NFKB1 protein binds to RELA protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]]
FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]; NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]
CTD PMID:16637064 PMID:21146893 PMID:24457827 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
increases degradation
decreases expression
ISO Cycloheximide inhibits the reaction [Morphine results in increased expression of NFKBIA mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NFKBIA mRNA]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; NFKBIA protein affects the reaction [Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in decreased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased degradation of NFKBIA protein] CTD PMID:11007951 PMID:15330761 PMID:16637064 PMID:21692457 PMID:22258905 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Cycloheximide inhibits the reaction [NGF protein results in increased expression of FOS protein]; Cycloheximide inhibits the reaction [NGF protein results in increased expression of SOD2 protein] CTD PMID:20495008 NCBI chr 3:102,377,235...102,428,329
Ensembl chr 3:102,377,235...102,428,329
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of NLRP3 protein] CTD PMID:26901245 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Cycloheximide inhibits the reaction [[Raloxifene Hydrochloride co-treated with 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] results in increased expression of NOS2 protein]; Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of NOS2 protein]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NOS2 mRNA] CTD PMID:10760090 PMID:11007951 PMID:28138957 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NOS3 mRNA] CTD PMID:11007951 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Npy1r neuropeptide Y receptor Y1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of NPY1R mRNA] CTD PMID:11007951 NCBI chr 8:67,149,595...67,159,452
Ensembl chr 8:67,149,844...67,159,444
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 decreases expression
multiple interactions
EXP
ISO
Cycloheximide results in decreased expression of NQO1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]]; Cycloheximide inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [arsenite results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Cadmium results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Cycloheximide promotes the reaction [Chromium results in increased expression of NQO1 mRNA]; Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]
Cycloheximide inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]
CTD PMID:14510636 PMID:16243960 PMID:18474416 PMID:24437944 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions EXP Cycloheximide inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA] CTD PMID:18787026 NCBI chr  X:85,235,381...85,239,553
Ensembl chr  X:85,235,370...85,239,553
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NR1H3 mRNA
Cycloheximide results in increased expression of NR1H3 mRNA
CTD PMID:19684285 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP
ISO
Cycloheximide inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]; Cycloheximide inhibits the reaction [Dexamethasone binds to NR3C1 protein]; Cycloheximide inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein]
Cycloheximide promotes the reaction [tubacin results in decreased expression of and results in increased degradation of NR3C1 mRNA]
CTD PMID:21569845 PMID:31778773 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO Cycloheximide promotes the reaction [LHB protein results in increased expression of NR4A1 mRNA] CTD PMID:11416027 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of NUCKS1 mRNA CTD PMID:19684285 NCBI chr 1:131,838,196...131,864,059
Ensembl chr 1:131,838,272...131,864,059
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 multiple interactions ISO Cycloheximide inhibits the reaction [Paraquat results in increased activity of ODC1 protein] CTD PMID:7662713 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO Cycloheximide inhibits the reaction [15-deoxyprostaglandin J2 results in increased expression of OPA1 protein alternative form] CTD PMID:20678484 NCBI chr16:29,398,099...29,481,924
Ensembl chr16:29,398,152...29,473,702
JBrowse link
G Oprk1 opioid receptor, kappa 1 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of OPRK1 mRNA
Cycloheximide results in increased expression of OPRK1 mRNA
CTD PMID:19684285 NCBI chr 1:5,658,673...5,676,357
Ensembl chr 1:5,658,689...5,676,354
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO Cycloheximide inhibits the reaction [Dronabinol results in increased expression of OPRM1 mRNA] CTD PMID:16434616 NCBI chr10:6,708,593...6,988,209
Ensembl chr10:6,708,506...6,988,198
JBrowse link
G Orm1 orosomucoid 1 multiple interactions ISO Cycloheximide inhibits the reaction [Dexamethasone results in increased expression of ORM1 mRNA] CTD PMID:20599767 NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400
JBrowse link
G Pa2g4 proliferation-associated 2G4 multiple interactions ISO PA2G4 protein promotes the reaction [Cycloheximide results in decreased expression of ERBB2 protein] CTD PMID:20379846 NCBI chr10:128,393,635...128,401,803
Ensembl chr10:128,393,635...128,401,856
JBrowse link
G Pappa pregnancy-associated plasma protein A increases expression
multiple interactions
ISO Cycloheximide results in increased expression of PAPPA mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PAPPA mRNA
CTD PMID:19684285 NCBI chr 4:65,041,993...65,276,776
Ensembl chr 4:65,042,411...65,275,746
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO [Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]
Cycloheximide results in increased cleavage of PARP1 protein
Cycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]
CTD PMID:12925536 PMID:15147502 PMID:16051428 PMID:18222423 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pax3 paired box 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PAX3 mRNA] CTD PMID:11007951 NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771
JBrowse link
G Pcgf1 polycomb group ring finger 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PCGF1 mRNA CTD PMID:19684285 NCBI chr 6:83,047,573...83,057,836
Ensembl chr 6:83,054,850...83,057,836
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions EXP Cycloheximide inhibits the reaction [Dexamethasone results in decreased expression of PCK1 mRNA] CTD PMID:9518257 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Cycloheximide inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein] CTD PMID:21533478 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pdcd2 programmed cell death 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PDCD2 mRNA] CTD PMID:11007951 NCBI chr17:15,739,472...15,747,560
Ensembl chr17:15,739,470...15,747,563
JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha multiple interactions ISO Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PI4KA mRNA] CTD PMID:11007951 NCBI chr16:17,098,215...17,224,178
Ensembl chr16:17,098,215...17,224,178
JBrowse link
G Pigh phosphatidylinositol glycan anchor biosynthesis, class H multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIGH mRNA] CTD PMID:11007951 NCBI chr12:79,127,443...79,136,478
Ensembl chr12:79,127,438...79,136,425
JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIGK mRNA] CTD PMID:11007951 NCBI chr 3:152,419,718...152,548,705
Ensembl chr 3:152,419,737...152,686,045
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIK3C3 mRNA] CTD PMID:11007951 NCBI chr18:30,390,441...30,481,179
Ensembl chr18:30,405,800...30,481,179
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PIK3CG mRNA] CTD PMID:11007951 NCBI chr12:32,223,128...32,258,675
Ensembl chr12:32,223,472...32,258,658
JBrowse link
G Pilrb2 paired immunoglobin-like type 2 receptor beta 2 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PILRB mRNA CTD PMID:19684285 NCBI chr 5:137,864,083...137,870,083
Ensembl chr 5:137,864,089...137,870,077
JBrowse link
G Pla2g1b phospholipase A2, group IB, pancreas multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G1B mRNA] CTD PMID:11007951 NCBI chr 5:115,604,201...115,612,781
Ensembl chr 5:115,604,321...115,612,781
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) multiple interactions EXP Cycloheximide inhibits the reaction [Dexamethasone inhibits the reaction [Zymosan results in increased activity of PLA2G4A protein]] CTD PMID:10874129 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Plat plasminogen activator, tissue multiple interactions ISO Cycloheximide promotes the reaction [Isoproterenol results in increased expression of PLAT mRNA] CTD PMID:2477232 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions
increases expression
ISO [Cycloheximide co-treated with IFNA2 protein] results in increased expression of PLAUR mRNA; [Cycloheximide co-treated with IFNG protein] results in increased expression of PLAUR mRNA
Cycloheximide results in increased expression of PLAUR mRNA
CTD PMID:12070711 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
G Pld3 phospholipase D family member 3 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of PLD3 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PLD3 mRNA
CTD PMID:19684285 NCBI chr 7:27,231,090...27,252,511
Ensembl chr 7:27,231,425...27,252,643
JBrowse link
G Pln phospholamban multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PLN mRNA] CTD PMID:11007951 NCBI chr10:53,213,782...53,222,095
Ensembl chr10:53,213,763...53,222,083
JBrowse link
G Plp1 proteolipid protein (myelin) 1 multiple interactions
increases expression
ISO Cycloheximide promotes the reaction [Tretinoin results in increased expression of PLP1 mRNA]
Cycloheximide results in increased expression of PLP1 mRNA
CTD PMID:19450544 NCBI chr  X:135,720,897...135,739,331
Ensembl chr  X:135,723,420...135,740,482
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [Fenretinide results in increased expression of PMAIP1 protein]; Cycloheximide inhibits the reaction [Thapsigargin results in increased expression of PMAIP1 protein] CTD PMID:17216584 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pml promyelocytic leukemia decreases degradation
multiple interactions
ISO Cycloheximide results in decreased degradation of PML protein modified form
Cycloheximide inhibits the reaction [arsenic trioxide results in increased degradation of PML protein]
CTD PMID:20943951 PMID:26049103 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069
JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 multiple interactions EXP Cycloheximide inhibits the reaction [rosiglitazone results in increased expression of PNPLA2 protein] CTD PMID:18643838 NCBI chr 7:141,035,101...141,040,656
Ensembl chr 7:141,035,111...141,040,656
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 multiple interactions ISO Cycloheximide inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of PNPLA6 protein]; Cycloheximide inhibits the reaction [Bucladesine results in increased activity of PNPLA6 protein]; Cycloheximide inhibits the reaction [Colforsin results in increased activity of PNPLA6 protein] CTD PMID:20380879 NCBI chr 8:3,565,341...3,594,267
Ensembl chr 8:3,565,384...3,594,267
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions ISO Cycloheximide inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones] CTD PMID:2993719 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
decreases expression
ISO POR protein mutant form promotes the reaction [Cycloheximide results in decreased expression of POR protein] CTD PMID:27496950 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Pou5f1 POU domain, class 5, transcription factor 1 multiple interactions ISO Cycloheximide promotes the reaction [Cobalt results in increased expression of POU5F1 protein]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of POU5F1 protein] CTD PMID:24497960 NCBI chr17:35,816,929...35,821,674
Ensembl chr17:35,816,915...35,821,669
JBrowse link
G Ppan peter pan homolog multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PPAN mRNA CTD PMID:19684285 NCBI chr 9:20,799,471...20,803,475
Ensembl chr 9:20,799,471...20,803,474
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions
decreases expression
ISO arsenite inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein]; Cycloheximide affects the reaction [arsenite results in increased expression of PPP1R15A protein]; Cycloheximide inhibits the reaction [Thapsigargin results in increased expression of PPP1R15A protein] CTD PMID:29109149 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPP3CB mRNA] CTD PMID:11007951 NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641
JBrowse link
G Ppp4r3b protein phosphatase 4 regulatory subunit 3B multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PPP4R3B mRNA CTD PMID:19684285 NCBI chr11:29,118,053...29,170,797
Ensembl chr11:29,122,890...29,170,797
JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNA] CTD PMID:11007951 NCBI chr  X:154,106,914...154,125,268
Ensembl chr  X:154,106,914...154,123,750
JBrowse link
G Prkcb protein kinase C, beta decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of PRKCB mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PRKCB mRNA
CTD PMID:19684285 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO Cycloheximide inhibits the reaction [Buthionine Sulfoximine results in increased expression of PRKCD protein]; Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCD protein] CTD PMID:11118818 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO Cycloheximide inhibits the reaction [Buthionine Sulfoximine results in increased expression of PRKCE protein]; Cycloheximide inhibits the reaction [diethyl maleate results in increased expression of PRKCE protein] CTD PMID:11118818 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347
JBrowse link
G Prkcz protein kinase C, zeta multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRKCZ mRNA] CTD PMID:11007951 NCBI chr 4:155,344,579...155,445,856
Ensembl chr 4:155,344,586...155,445,818
JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [PSEN1 protein affects the susceptibility to Ammonium Chloride] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to SB 203580] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide affects the reaction [PSEN1 protein affects the expression of RBPJ protein] CTD PMID:22302987 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973
JBrowse link
G Psen2 presenilin 2 multiple interactions ISO Cycloheximide affects the reaction [PSEN2 protein affects the expression of RBPJ protein]; PSEN2 protein affects the reaction [Cycloheximide results in decreased expression of RBPJ protein] CTD PMID:22302987 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003
JBrowse link
G Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 multiple interactions ISO PSMD1 protein affects the reaction [Cycloheximide results in increased degradation of MAF1 protein] CTD PMID:31645432 NCBI chr 1:85,992,341...86,067,017
Ensembl chr 1:85,992,109...86,066,873
JBrowse link
G Psme3 proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) multiple interactions ISO PSME3 protein affects the reaction [Cycloheximide results in decreased expression of CDKN1A protein] CTD PMID:31645432 NCBI chr11:101,206,090...101,214,363
Ensembl chr11:101,207,039...101,214,363
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO Cycloheximide affects the reaction [sodium arsenite affects the expression of PTEN protein]; Cycloheximide inhibits the reaction [Lovastatin results in increased expression of PTEN protein]; Cycloheximide inhibits the reaction [Rosiglitazone results in increased expression of PTEN protein] CTD PMID:16425225 PMID:33256086 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO Cycloheximide inhibits the reaction [Dinoprostone promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein]; Cycloheximide inhibits the reaction [Tretinoin results in increased expression of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]]; Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; Cycloheximide inhibits the reaction [KNG1 protein results in increased phosphorylation of PTGS2 protein]; Cycloheximide promotes the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
Cycloheximide results in increased expression of PTGS2 mRNA
CTD PMID:7575673 PMID:11112151 PMID:11286988 PMID:16696851 PMID:16894348 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptn pleiotrophin increases expression
multiple interactions
ISO Cycloheximide results in increased expression of PTN mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PTN mRNA
CTD PMID:19684285 NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4a1 multiple interactions ISO Cycloheximide inhibits the reaction [Medroxyprogesterone Acetate inhibits the reaction [Estradiol results in increased expression of PTP4A1 mRNA]]; Cycloheximide promotes the reaction [Estradiol results in increased expression of PTP4A1 mRNA] CTD PMID:19146866 NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390
JBrowse link
G Ptp4a3 protein tyrosine phosphatase 4a3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PTP4A3 mRNA CTD PMID:19684285 NCBI chr15:73,594,991...73,629,075
Ensembl chr15:73,594,994...73,630,615
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 multiple interactions ISO Cycloheximide inhibits the reaction [Isoproterenol results in increased expression of PTPN5 protein] CTD PMID:17623046 NCBI chr 7:46,727,543...46,783,774
Ensembl chr 7:46,727,543...46,783,432
JBrowse link
G Rabepk Rab9 effector protein with kelch motifs affects response to substance ISO RABEPK gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 2:34,662,946...34,690,200
Ensembl chr 2:34,667,568...34,689,924
JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RAPGEF1 mRNA CTD PMID:19684285 NCBI chr 2:29,509,732...29,630,376
Ensembl chr 2:29,509,732...29,630,990
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
increases expression
ISO Cycloheximide promotes the reaction [Tretinoin results in increased expression of RARB mRNA]
Cycloheximide results in increased expression of RARB mRNA
CTD PMID:19450544 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924
JBrowse link
G Rarres2 retinoic acid receptor responder (tazarotene induced) 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of RARRES2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RARRES2 mRNA
CTD PMID:19684285 NCBI chr 6:48,546,630...48,549,778
Ensembl chr 6:48,546,630...48,549,723
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] CTD PMID:20100483 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of RBL1 mRNA]; palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]; RB1 protein affects the reaction [palbociclib promotes the reaction [Cycloheximide results in decreased expression of RBL1 protein]] CTD PMID:11007951 PMID:20100483 NCBI chr 2:156,987,813...157,046,454
Ensembl chr 2:156,987,813...157,046,454
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of RBPJ protein
[PSEN1 protein affects the susceptibility to Ammonium Chloride] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; [PSEN1 protein affects the susceptibility to SB 203580] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide affects the reaction [PSEN1 protein affects the expression of RBPJ protein]; Cycloheximide affects the reaction [PSEN2 protein affects the expression of RBPJ protein]; Cycloheximide inhibits the reaction [Ammonium Chloride results in increased expression of RBPJ protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Cycloheximide results in decreased expression of RBPJ protein]; PSEN2 protein affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]
CTD PMID:22302987 NCBI chr 5:53,713,121...53,814,787
Ensembl chr 5:53,623,494...53,814,704
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
affects localization
ISO [Cycloheximide co-treated with N(1),N(11)-diethylnorspermine] promotes the reaction [RELA protein binds to SAT1 promoter]; Cycloheximide promotes the reaction [RELA protein binds to SAT1 promoter]; Cycloheximide results in decreased expression of [NFKB1 protein binds to RELA protein]
Cycloheximide affects the localization of RELA protein
CTD PMID:16637064 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Ren1 renin 1 structural multiple interactions ISO Cycloheximide inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Cycloheximide inhibits the reaction [Terbutaline results in increased secretion of REN protein] CTD PMID:9203624 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063
JBrowse link
G Ret ret proto-oncogene decreases expression ISO Cycloheximide results in decreased expression of RET protein CTD PMID:17555550 NCBI chr 6:118,128,709...118,174,705
Ensembl chr 6:118,128,706...118,174,679
JBrowse link
G Rgn regucalcin multiple interactions EXP Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RGN mRNA] CTD PMID:18327666 NCBI chr  X:20,413,980...20,428,328
Ensembl chr  X:20,416,026...20,428,328
JBrowse link
G Rhob ras homolog family member B multiple interactions EXP Cycloheximide inhibits the reaction [cytotoxic necrotizing factor type 1 results in increased expression of RHOB protein] CTD PMID:23732113 NCBI chr12:8,547,661...8,550,009
Ensembl chr12:8,547,661...8,550,009
JBrowse link
G Rhoc ras homolog family member C decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of RHOC protein
RNF168 protein promotes the reaction [Cycloheximide results in decreased expression of RHOC protein]
CTD PMID:34873829 NCBI chr 3:104,696,350...104,701,775
Ensembl chr 3:104,695,691...104,701,775
JBrowse link
G Rictor RPTOR independent companion of MTOR, complex 2 multiple interactions ISO
EXP
Cycloheximide promotes the reaction [FBXW7 protein binds to and results in decreased expression of RICTOR protein]
Cycloheximide inhibits the reaction [Thapsigargin affects the localization of RICTOR mRNA]
CTD PMID:25897075 PMID:29576526 NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882
JBrowse link
G Rnf168 ring finger protein 168 multiple interactions ISO RNF168 protein promotes the reaction [Cycloheximide results in decreased expression of RHOC protein] CTD PMID:34873829 NCBI chr16:32,096,279...32,120,260
Ensembl chr16:32,096,277...32,120,252
JBrowse link
G Rnf4 ring finger protein 4 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of RNF4 protein
Cycloheximide inhibits the reaction [TAK-243 affects the localization of RNF4 protein]
CTD PMID:20943951 PMID:31285264 NCBI chr 5:34,493,594...34,510,789
Ensembl chr 5:34,493,633...34,512,973
JBrowse link
G Rps27l ribosomal protein S27-like multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of RPS27L mRNA CTD PMID:19684285 NCBI chr 9:66,851,906...66,856,804
Ensembl chr 9:66,853,368...66,856,798
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 multiple interactions ISO Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] CTD PMID:22689575 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Rrm2 ribonucleotide reductase M2 multiple interactions EXP Cycloheximide inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA] CTD PMID:22403396 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
JBrowse link
G Runx2 runt related transcription factor 2 multiple interactions EXP Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of RUNX2 mRNA]; Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of RUNX2 mRNA] CTD PMID:15962303 PMID:18327666 NCBI chr17:44,806,873...45,125,518
Ensembl chr17:44,806,874...45,125,684
JBrowse link
G S100a4 S100 calcium binding protein A4 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of S100A4 mRNA] CTD PMID:11007951 NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352
JBrowse link
G S100b S100 protein, beta polypeptide, neural decreases expression ISO Cycloheximide results in decreased expression of S100B mRNA CTD PMID:19146868 NCBI chr10:76,089,670...76,097,153
Ensembl chr10:76,089,687...76,096,993
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Cycloheximide co-treated with N(1),N(11)-diethylnorspermine] promotes the reaction [RELA protein binds to SAT1 promoter]; Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]; Cycloheximide promotes the reaction [RELA protein binds to SAT1 promoter]; NFKBIA protein affects the reaction [Cycloheximide promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA]] CTD PMID:16637064 NCBI chr  X:153,996,128...153,999,345
Ensembl chr  X:153,996,128...153,999,445
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions EXP Cycloheximide inhibits the reaction [Clofibrate results in increased expression of SCD1 mRNA] CTD PMID:8790349 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Sec11c SEC11 homolog C, signal peptidase complex subunit multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] affects the expression of SEC11C mRNA CTD PMID:19684285 NCBI chr18:65,933,649...65,950,731
Ensembl chr18:65,933,586...65,950,755
JBrowse link
G Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 multiple interactions ISO Cycloheximide promotes the reaction [moxestrol results in increased expression of SERPINB9 mRNA] CTD PMID:10681578 NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions EXP
ISO
Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]
Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA]
Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Cycloheximide promotes the reaction [FGF2 protein results in increased expression of SERPINE1 mRNA]
CTD PMID:9798919 PMID:11007951 PMID:12111005 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SERPINE2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SERPINE2 mRNA
CTD PMID:19684285 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897
JBrowse link
G Sertad2 SERTA domain containing 2 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SERTAD2 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SERTAD2 mRNA
CTD PMID:19684285 NCBI chr11:20,493,166...20,603,023
Ensembl chr11:20,493,253...20,603,021
JBrowse link
G Sesn2 sestrin 2 multiple interactions
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein]; Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of SESN2 protein] CTD PMID:25637945 NCBI chr 4:132,220,115...132,237,767
Ensembl chr 4:132,219,343...132,237,812
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Cadmium Chloride results in increased expression of SGK1 protein] CTD PMID:25128767 NCBI chr10:21,758,083...21,875,802
Ensembl chr10:21,758,083...21,875,802
JBrowse link
G Sirpa signal-regulatory protein alpha multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SIRPA mRNA] CTD PMID:11007951 NCBI chr 2:129,432,962...129,474,148
Ensembl chr 2:129,434,755...129,474,148
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO Cycloheximide promotes the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; pyrazolanthrone inhibits the reaction [Silicon Dioxide promotes the reaction [Cycloheximide results in decreased expression of SIRT1 protein]]; Silicon Dioxide promotes the reaction [Cycloheximide results in decreased expression of SIRT1 protein] CTD PMID:30055241 PMID:31082419 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Sla src-like adaptor multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in increased expression of SLA mRNA] CTD PMID:9020066 NCBI chr15:66,652,713...66,703,921
Ensembl chr15:66,652,668...66,703,678
JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC16A1 mRNA CTD PMID:19684285 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778
JBrowse link
G Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tretinoin results in increased expression of SLC1A1 mRNA] CTD PMID:19450544 NCBI chr19:28,812,535...28,891,360
Ensembl chr19:28,812,449...28,891,360
JBrowse link
G Slc22a4 solute carrier family 22 (organic cation transporter), member 4 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SLC22A4 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC22A4 mRNA
CTD PMID:19684285 NCBI chr11:53,873,941...53,920,866
Ensembl chr11:53,873,949...53,918,916
JBrowse link
G Slc25a27 solute carrier family 25, member 27 increases expression ISO Cycloheximide results in increased expression of SLC25A27 mRNA CTD PMID:20385226 NCBI chr17:43,948,630...43,978,105
Ensembl chr17:43,952,782...43,978,105
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC2A1 mRNA CTD PMID:19684285 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 multiple interactions ISO Cycloheximide inhibits the reaction [4-hydroxyisoleucine results in increased localization of SLC2A4 protein] CTD PMID:22610671 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014
JBrowse link
G Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 multiple interactions ISO Cycloheximide inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]] CTD PMID:11123204 NCBI chr 4:150,203,801...150,228,625
Ensembl chr 4:150,203,740...150,228,626
JBrowse link
G Slc39a4 solute carrier family 39 (zinc transporter), member 4 multiple interactions EXP Cycloheximide inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Cycloheximide inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA] CTD PMID:18020946 NCBI chr15:76,496,583...76,501,579
Ensembl chr15:76,496,583...76,501,584
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 increases expression ISO Cycloheximide results in increased expression of SLC3A2 mRNA CTD PMID:26621329 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 increases expression ISO Cycloheximide results in increased expression of SLC5A5 mRNA CTD PMID:17164311 NCBI chr 8:71,335,529...71,345,429
Ensembl chr 8:71,335,533...71,345,401
JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SLC7A5 mRNA CTD PMID:19684285 NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433
JBrowse link
G Smn1 survival motor neuron 1 multiple interactions ISO Cycloheximide inhibits the reaction [Paraquat results in increased expression of SMN1 mRNA alternative form] CTD PMID:17064354 NCBI chr13:100,259,713...100,274,206
Ensembl chr13:100,261,360...100,274,198
JBrowse link
G Snhg15 small nucleolar RNA host gene 15 multiple interactions ISO Cycloheximide results in increased stability of and results in increased expression of SNHG15 mRNA CTD PMID:24036268 NCBI chr11:6,475,591...6,478,760
Ensembl chr11:6,475,295...6,478,841
JBrowse link
G Snw1 SNW domain containing 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SNW1 mRNA CTD PMID:19684285 NCBI chr12:87,496,680...87,519,069
Ensembl chr12:87,495,845...87,519,044
JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions
increases expression
ISO
EXP
[afimoxifene co-treated with Cycloheximide] results in increased expression of SOCS1 mRNA
Cycloheximide results in increased expression of SOCS1 mRNA
CTD PMID:16849584 PMID:23237828 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions
increases expression
EXP Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS2 mRNA]
Cycloheximide results in increased expression of SOCS2 mRNA
CTD PMID:15371557 PMID:23237828 NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression
multiple interactions
EXP Cycloheximide results in increased expression of SOCS3 mRNA
Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of SOCS3 mRNA]; U 0126 inhibits the reaction [Cycloheximide results in increased expression of SOCS3 mRNA]
CTD PMID:23237828 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Socs4 suppressor of cytokine signaling 4 increases expression EXP Cycloheximide results in increased expression of SOCS4 mRNA CTD PMID:23237828 NCBI chr14:47,514,377...47,533,559
Ensembl chr14:47,514,388...47,533,559
JBrowse link
G Socs5 suppressor of cytokine signaling 5 increases expression EXP Cycloheximide results in increased expression of SOCS5 mRNA CTD PMID:23237828 NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267
JBrowse link
G Socs6 suppressor of cytokine signaling 6 increases expression EXP Cycloheximide results in increased expression of SOCS6 mRNA CTD PMID:23237828 NCBI chr18:88,883,293...88,912,623
Ensembl chr18:88,683,348...88,945,605
JBrowse link
G Socs7 suppressor of cytokine signaling 7 increases expression EXP Cycloheximide results in increased expression of SOCS7 mRNA CTD PMID:23237828 NCBI chr11:97,253,044...97,289,368
Ensembl chr11:97,253,261...97,289,368
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions
increases expression
EXP
ISO
Cycloheximide inhibits the reaction [NGF protein results in increased expression of SOD2 protein]; Cycloheximide inhibits the reaction [polysaccharide-K results in increased expression of SOD2]
Cycloheximide promotes the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA]
CTD PMID:8037686 PMID:9852137 PMID:11154046 PMID:15330761 PMID:20495008 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sort1 sortilin 1 multiple interactions
increases degradation
ISO
EXP
SORT1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; SORT1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]
Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]; Docosahexaenoic Acids inhibits the reaction [Cycloheximide promotes the reaction [Palmitic Acid results in increased degradation of SORT1 protein]]
Cycloheximide results in increased degradation of SORT1 protein mutant form
CTD PMID:22555848 PMID:24986865 PMID:25805502 NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOS1 mRNA] CTD PMID:11007951 NCBI chr17:80,701,181...80,787,882
Ensembl chr17:80,701,180...80,787,882
JBrowse link
G Sptan1 spectrin alpha, non-erythrocytic 1 multiple interactions EXP [TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein; VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein] CTD PMID:18182247 NCBI chr 2:29,855,572...29,921,463
Ensembl chr 2:29,855,572...29,921,463
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression
ISO [sodium arsenite results in increased abundance of arsenite] inhibits the reaction [Cycloheximide results in decreased expression of SQSTM1 protein]; Cycloheximide promotes the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of SQSTM1 protein]] CTD PMID:31781319 PMID:34405320 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Src Rous sarcoma oncogene increases localization ISO Cycloheximide results in increased localization of SRC protein CTD PMID:10401681 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Srr serine racemase multiple interactions ISO Cycloheximide inhibits the reaction [methyllycaconitine results in increased expression of SRR protein] CTD PMID:24012499 NCBI chr11:74,794,853...74,818,427
Ensembl chr11:74,797,185...74,816,774
JBrowse link
G Ssbp1 single-stranded DNA binding protein 1 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of SSBP1 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SSBP1 mRNA
CTD PMID:19684285 NCBI chr 6:40,448,302...40,458,757
Ensembl chr 6:40,448,286...40,461,634
JBrowse link
G St18 suppression of tumorigenicity 18 increases expression EXP Cycloheximide results in increased expression of ST18 mRNA CTD PMID:23236509 NCBI chr 1:6,557,455...6,931,164
Ensembl chr 1:6,557,455...6,931,164
JBrowse link
G St8sia1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of ST8SIA1 mRNA
Cycloheximide results in increased expression of ST8SIA1 mRNA
CTD PMID:19684285 NCBI chr 6:142,767,267...142,935,247
Ensembl chr 6:142,767,271...142,910,178
JBrowse link
G Stk3 serine/threonine kinase 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of STK3 mRNA] CTD PMID:11007951 NCBI chr15:34,875,645...35,155,990
Ensembl chr15:34,875,642...35,179,067
JBrowse link
G Stx2 syntaxin 2 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of STX2 mRNA] CTD PMID:11007951 NCBI chr 5:129,061,621...129,085,664
Ensembl chr 5:129,061,621...129,085,638
JBrowse link
G Sult2b1 sulfotransferase family, cytosolic, 2B, member 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SULT2B1 mRNA] CTD PMID:11007951 NCBI chr 7:45,379,405...45,409,096
Ensembl chr 7:45,379,407...45,434,093
JBrowse link
G Supt4a SPT4A, DSIF elongation factor subunit multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of SUPT4H1 mRNA] CTD PMID:11007951 NCBI chr11:87,628,377...87,634,449
Ensembl chr11:87,628,378...87,634,449
JBrowse link
G Synpo synaptopodin multiple interactions
increases expression
ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of SYNPO mRNA
Cycloheximide results in increased expression of SYNPO mRNA
CTD PMID:19684285 NCBI chr18:60,727,053...60,793,241
Ensembl chr18:60,727,045...60,793,214
JBrowse link
G Tac1 tachykinin 1 multiple interactions ISO Cycloheximide inhibits the reaction [KNG1 protein results in increased secretion of TAC1 protein] CTD PMID:16696851 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tacc1 transforming, acidic coiled-coil containing protein 1 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of TACC1 mRNA
Cycloheximide results in increased expression of TACC1 mRNA
CTD PMID:15072547 NCBI chr 8:25,644,568...25,730,901
Ensembl chr 8:25,644,568...25,746,604
JBrowse link
G Tardbp TAR DNA binding protein decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of TARDBP protein
Cycloheximide results in decreased expression of and results in decreased stability of TARDBP protein mutant form; epoxomicin inhibits the reaction [Cycloheximide results in decreased expression of and results in decreased stability of TARDBP protein mutant form]; epoxomicin inhibits the reaction [Cycloheximide results in decreased expression of TARDBP protein]
CTD PMID:24477737 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476
JBrowse link
G Tas2r105 taste receptor, type 2, member 105 multiple interactions EXP Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in decreased abundance of Cyclic AMP]]; Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein]]; Pertussis Toxin inhibits the reaction [TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein]]; TAS2R105 protein affects the reaction [Cycloheximide results in decreased abundance of Cyclic AMP] CTD PMID:15087236 NCBI chr 6:131,663,524...131,664,426
Ensembl chr 6:131,663,495...131,664,458
JBrowse link
G Tas2r114 taste receptor, type 2, member 114 multiple interactions ISO TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK1 protein]; TAS2R105 protein affects the reaction [Cycloheximide results in increased phosphorylation of MAPK3 protein] CTD PMID:15087236 NCBI chr 6:131,666,097...131,667,026
Ensembl chr 6:131,666,097...131,667,026
JBrowse link
G Tbx3 T-box 3 increases expression ISO cycloheximide co-treated with all-trans-retinoic acid increases expression of TBX3 mRNA in melanoma cells RGD PMID:22535523 RGD:151361117 NCBI chr 5:119,808,600...119,822,789
Ensembl chr 5:119,808,734...119,822,789
JBrowse link
G Tfap2a transcription factor AP-2, alpha decreases stability
multiple interactions
ISO Cycloheximide results in decreased stability of TFAP2A protein
LINC-ROR promotes the reaction [Cycloheximide results in decreased stability of TFAP2A protein]
CTD PMID:36576707 NCBI chr13:40,867,278...40,891,715
Ensembl chr13:40,868,778...40,891,852
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO [Cycloheximide co-treated with Estradiol] results in increased expression of TFF1 mRNA; Cycloheximide inhibits the reaction [bisphenol A results in increased expression of TFF1 mRNA]
Cycloheximide results in increased expression of TFF1 mRNA
CTD PMID:15072547 PMID:20875696 NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251
JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Cycloheximide results in increased expression of TGFA mRNA CTD PMID:15228094 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases activity
ISO Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of BAX protein]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]
Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]]; Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Cycloheximide inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA]; Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of ITGB6 mRNA]
Cycloheximide results in decreased activity of TGFB1 protein
CTD PMID:9145908 PMID:9790906 PMID:9798919 PMID:21303922 PMID:31652400 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor II multiple interactions ISO Cycloheximide inhibits the reaction [tolfenamic acid results in decreased expression of TGFBR2 protein] CTD PMID:31381904 NCBI chr 9:115,916,763...116,004,431
Ensembl chr 9:115,913,361...116,004,428
JBrowse link
G Thbd thrombomodulin multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of THBD mRNA] CTD PMID:11007951 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108
JBrowse link
G Thbs1 thrombospondin 1 multiple interactions EXP Cycloheximide inhibits the reaction [Testosterone results in decreased expression of THBS1 mRNA] CTD PMID:16723184 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614
JBrowse link
G Thy1 thymus cell antigen 1, theta multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of THY1 mRNA] CTD PMID:11007951 NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876
JBrowse link
G Tia1 cytotoxic granule-associated RNA binding protein 1 multiple interactions ISO Cycloheximide inhibits the reaction [sodium arsenite affects the localization of TIA1 protein]; TIA1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; TIA1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]] CTD PMID:19171178 PMID:22555848 NCBI chr 6:86,381,001...86,410,387
Ensembl chr 6:86,381,201...86,410,387
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17a multiple interactions
decreases expression
ISO
EXP
Cycloheximide results in decreased expression of and results in increased degradation of TIMM17A protein; YME1L1 mutant form inhibits the reaction [Cycloheximide results in increased degradation of TIMM17A protein]
Cycloheximide results in decreased expression of TIMM17A protein
CTD PMID:24315374 NCBI chr 1:135,229,273...135,241,475
Ensembl chr 1:135,222,951...135,241,516
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 decreases response to substance ISO TIMP1 protein results in decreased susceptibility to Cycloheximide CTD PMID:15860571 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions
increases expression
EXP AHR protein promotes the reaction [Cycloheximide results in increased expression of TIPARP mRNA]; Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] CTD PMID:12147270 NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [IFNG protein results in increased expression of TJP1 protein]
Cycloheximide results in decreased expression of TJP1 protein
CTD PMID:16087364 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of TM7SF3 mRNA CTD PMID:19684285 NCBI chr 6:146,503,774...146,536,103
Ensembl chr 6:146,503,850...146,544,322
JBrowse link
G Tmem263 transmembrane protein 263 increases expression
multiple interactions
ISO Cycloheximide results in increased expression of TMEM263 mRNA
[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of TMEM263 mRNA
CTD PMID:19684285 NCBI chr10:84,938,491...84,953,611
Ensembl chr10:84,938,491...84,956,482
JBrowse link
G Tnf tumor necrosis factor increases response to substance
multiple interactions
ISO
EXP
TNF protein results in increased susceptibility to Cycloheximide
[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein; Cycloheximide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]; Cycloheximide inhibits the reaction [Poly I-C results in increased secretion of TNF protein]; Cycloheximide promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein]
Cycloheximide inhibits the reaction [TNF protein results in decreased export of Potassium]; Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]; sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]; SORT1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; SORT1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; TIA1 mutant form inhibits the reaction [Pentanoic Acids results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]; TIA1 mutant form inhibits the reaction [sodium arsenite results in decreased susceptibility to [TNF protein co-treated with Cycloheximide]]
[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein; [Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein; [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein; [Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein; [Cycloheximide co-treated with TNF] results in increased cleavage of BID protein; [TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA; [TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein; Cycloheximide inhibits the reaction [CXCL8 protein affects the secretion of TNF protein]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CNR1 mRNA]]; Cycloheximide inhibits the reaction [Morphine inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]]; Cycloheximide inhibits the reaction [SM 164 results in increased expression of TNF mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]; Cycloheximide inhibits the reaction [TNF protein results in increased expression of MYLK protein]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL2 protein]]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CCL5 protein]]; Cycloheximide inhibits the reaction [tofacitinib inhibits the reaction [TNF protein results in increased expression of CXCL10 protein]]; Cycloheximide inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Cycloheximide promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased activity of CASP9 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP3 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of and results in increased activity of CASP8 protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of BID protein]; ITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of BID protein]; ITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]; ITPK1 mutant form results in increased susceptibility to [Cycloheximide co-treated with TNF protein]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]; TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]; Ursodeoxycholic Acid analog inhibits the reaction [[TNF protein co-treated with Cycloheximide] results in increased secretion of CXCL8 protein]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL2 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CCL5 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of CXCL8 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of IL6 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased expression of NFKB1 mRNA]]; Ursodeoxycholic Acid analog inhibits the reaction [TNF protein promotes the reaction [Cycloheximide results in increased secretion of IL6 protein]]; Ursodeoxycholic Acid analog promotes the reaction [[TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA]
CTD PMID:8037686 PMID:8071060 PMID:12185005 PMID:12812920 PMID:12925536 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfaip1 tumor necrosis factor, alpha-induced protein 1 (endothelial) multiple interactions EXP TNFAIP1 protein inhibits the reaction [Cycloheximide results in decreased degradation of CSNK2B protein] CTD PMID:37302538 NCBI chr11:78,413,676...78,427,122
Ensembl chr11:78,413,676...78,427,158
JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 multiple interactions ISO [TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA; Ursodeoxycholic Acid analog promotes the reaction [[TNF protein co-treated with Cycloheximide] results in increased expression of TNFAIP3 mRNA] CTD PMID:21146893 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b multiple interactions ISO Cycloheximide inhibits the reaction [docetaxel results in increased expression of TNFRSF10A protein]; Cycloheximide inhibits the reaction [Paclitaxel results in increased expression of TNFRSF10A protein] CTD PMID:11212279 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
G Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of TNFRSF11B mRNA CTD PMID:19684285 NCBI chr15:54,114,014...54,141,700
Ensembl chr15:54,114,015...54,141,880
JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 multiple interactions ISO Cycloheximide inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B mRNA] CTD PMID:27484784 NCBI chr 7:143,188,540...143,203,412
Ensembl chr 7:143,188,543...143,203,398
JBrowse link
G Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNFRSF8 mRNA] CTD PMID:11007951 NCBI chr 4:144,993,702...145,041,734
Ensembl chr 4:144,993,707...145,041,734
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions ISO [Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein; [Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [sodium arsenite results in increased expression of and results in increased localization of TNFRSF10B protein]] results in increased susceptibility to [TNFSF10 protein co-treated with Cycloheximide]; BCL2 protein inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein]; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF10 mRNA] CTD PMID:11007951 PMID:18222423 PMID:22343715 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF11 mRNA]
Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Cryptoxanthins] promotes the reaction [Zinc Sulfate results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein co-treated with Zinc Sulfate] promotes the reaction [Cryptoxanthins results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Genistein promotes the reaction [[Zinc Sulfate co-treated with CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 mRNA]]; Cycloheximide inhibits the reaction [Zinc Sulfate results in increased expression of TNFSF11 mRNA]
CTD PMID:11007951 PMID:17295206 PMID:18327666 PMID:18636177 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Tnnc1 troponin C, cardiac/slow skeletal multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TNNC1 mRNA] CTD PMID:11007951 NCBI chr14:30,930,274...30,933,671
Ensembl chr14:30,930,269...30,933,686
JBrowse link
G Trp53 transformation related protein 53 increases response to substance
multiple interactions
decreases expression
increases degradation
ISO
EXP
TP53 mutant form results in increased susceptibility to Cycloheximide
Cycloheximide inhibits the reaction [Fluorouracil results in increased expression of TP53 protein]; Cycloheximide promotes the reaction [Chlorpyrifos results in decreased expression of TP53 protein]; leptomycin B inhibits the reaction [Cycloheximide results in increased degradation of TP53 protein]
Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of TP53 protein]
Cycloheximide inhibits the reaction [Cyclosporine results in increased expression of TRP53 protein]
Cycloheximide results in decreased expression of TP53 protein
CTD PMID:9790906 PMID:10760090 PMID:15016801 PMID:20943951 PMID:21875941 More... NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp53i11 transformation related protein 53 inducible protein 11 multiple interactions
decreases expression
ISO Cycloheximide inhibits the reaction [arsenic trioxide results in increased expression of TP53I11 mRNA]
Cycloheximide results in decreased expression of TP53I11 mRNA
CTD PMID:19333544 NCBI chr 2:93,017,694...93,032,102
Ensembl chr 2:93,017,893...93,032,104
JBrowse link
G Trp63 transformation related protein 63 multiple interactions ISO Cycloheximide inhibits the reaction [trichostatin A results in increased expression of TP63 protein alternative form] CTD PMID:20043870 NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852
JBrowse link
G Tubgcp3 tubulin, gamma complex component 3 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TUBGCP3 mRNA] CTD PMID:11007951 NCBI chr 8:12,664,277...12,722,141
Ensembl chr 8:12,664,277...12,722,248
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO Cycloheximide inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA]; Cycloheximide inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA] CTD PMID:12663510 PMID:15652504 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Tymp thymidine phosphorylase decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of TYMP protein
salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]; tanespimycin inhibits the reaction [salinomycin inhibits the reaction [Cycloheximide results in decreased expression of TYMP protein]]
CTD PMID:30796972 NCBI chr15:89,255,834...89,261,282
Ensembl chr15:89,256,134...89,261,242
JBrowse link
G Tyms thymidylate synthase multiple interactions
decreases expression
ISO cinobufagin promotes the reaction [Cycloheximide results in decreased expression of TYMS protein]; Cycloheximide inhibits the reaction [trichostatin A results in decreased expression of TYMS mRNA] CTD PMID:17172411 PMID:35427566 NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615
JBrowse link
G Tyr tyrosinase multiple interactions ISO
EXP
Cycloheximide inhibits the reaction [Quercetin results in increased activity of TYR protein]
[resorcinol co-treated with Cycloheximide] results in increased expression of TYR protein; SB 203580 inhibits the reaction [[resorcinol co-treated with Cycloheximide] results in increased expression of TYR protein]
CTD PMID:14717847 PMID:29621941 NCBI chr 7:87,073,979...87,142,637
Ensembl chr 7:87,073,979...87,142,720
JBrowse link
G Uchl1 ubiquitin carboxy-terminal hydrolase L1 multiple interactions ISO Cycloheximide inhibits the reaction [Mevinphos results in increased expression of UCHL1 protein] CTD PMID:15545831 NCBI chr 5:66,833,464...66,844,577
Ensembl chr 5:66,833,434...66,844,577
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 multiple interactions
decreases expression
ISO [Cycloheximide co-treated with Estradiol] results in decreased expression of UGT1A1 mRNA
Cycloheximide results in decreased expression of UGT1A1 mRNA
CTD PMID:15072547 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B multiple interactions ISO Cycloheximide inhibits the reaction [Paraquat results in increased expression of UGT1A6 mRNA] CTD PMID:22846377 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
JBrowse link
G Ulk1 unc-51 like kinase 1 decreases expression
multiple interactions
ISO Cycloheximide results in decreased expression of ULK1 protein
Antimycin A inhibits the reaction [Cycloheximide results in decreased expression of ULK1 protein]; Cycloheximide inhibits the reaction [Antimycin A results in increased expression of ULK1 protein]
CTD PMID:27629431 NCBI chr 5:110,932,355...110,957,991
Ensembl chr 5:110,932,354...110,957,963
JBrowse link
G Usp7 ubiquitin specific peptidase 7 multiple interactions ISO USP7 protein inhibits the reaction [Cycloheximide results in decreased expression of HMOX1 protein]; USP7 protein mutant form affects the reaction [Cycloheximide results in decreased expression of HMOX1 protein] CTD PMID:35821281 NCBI chr16:8,506,586...8,574,931
Ensembl chr16:8,507,459...8,610,172
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions EXP VASP mutant form promotes the reaction [[TNF co-treated with Cycloheximide] results in increased cleavage of SPTAN1 protein] CTD PMID:18182247 NCBI chr 7:18,990,854...19,005,779
Ensembl chr 7:18,990,854...19,005,742
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP Cycloheximide inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein] CTD PMID:12892526 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
ISO
EXP
Cycloheximide promotes the reaction [Estradiol results in increased expression of VEGFA mRNA alternative form]
[Cycloheximide co-treated with Norepinephrine] results in increased expression of VEGFA mRNA
Cycloheximide results in increased expression of VEGFA mRNA
Cycloheximide inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Cycloheximide promotes the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; Cycloheximide promotes the reaction [nickel chloride results in increased expression of VEGFA mRNA]; Cycloheximide promotes the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]
CTD PMID:8344219 PMID:8537383 PMID:10788502 PMID:11641398 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfd vascular endothelial growth factor D multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VEGFD mRNA] CTD PMID:11007951 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646
JBrowse link
G Virma vir like m6A methyltransferase associated affects response to substance ISO VIRMA gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 4:11,485,958...11,551,143
Ensembl chr 4:11,485,958...11,550,684
JBrowse link
G Vldlr very low density lipoprotein receptor multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VLDLR mRNA] CTD PMID:11007951 NCBI chr19:27,190,070...27,231,631
Ensembl chr19:27,193,884...27,231,631
JBrowse link
G Vsnl1 visinin-like 1 multiple interactions ISO Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of VSNL1 mRNA] CTD PMID:11007951 NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614
JBrowse link
G Wwox WW domain-containing oxidoreductase affects response to substance ISO WWOX gene SNP affects the susceptibility to Cycloheximide CTD PMID:25622337 NCBI chr 8:115,166,377...116,079,451
Ensembl chr 8:115,166,395...116,079,447
JBrowse link
G Xiap X-linked inhibitor of apoptosis multiple interactions EXP Cycloheximide inhibits the reaction [Thapsigargin affects the localization of XIAP mRNA] CTD PMID:29576526 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Yap1 yes-associated protein 1 multiple interactions ISO [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of YAP1 mRNA CTD PMID:19684285 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597
JBrowse link
G Yme1l1 YME1-like 1 (S. cerevisiae) multiple interactions ISO YME1L1 mutant form inhibits the reaction [Cycloheximide results in increased degradation of TIMM17A protein] CTD PMID:24315374 NCBI chr 2:23,046,517...23,089,272
Ensembl chr 2:23,046,381...23,089,272
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22182
    role 22167
      biological role 22166
        inhibitor 20017
          ferroptosis inhibitor 7989
            cycloheximide 476
Path 2
Term Annotations click to browse term
  CHEBI ontology 22182
    subatomic particle 22174
      composite particle 22174
        hadron 22174
          baryon 22174
            nucleon 22174
              atomic nucleus 22174
                atom 22174
                  main group element atom 22108
                    p-block element atom 22108
                      carbon group element atom 21909
                        carbon atom 21835
                          organic molecular entity 21835
                            organic molecule 21652
                              organic cyclic compound 21261
                                organic heterocyclic compound 20329
                                  organic heteromonocyclic compound 18734
                                    piperidines 7833
                                      piperidones 1551
                                        piperidine-2,6-dione 529
                                          cycloheximide 476
paths to the root