Rnf168 (ring finger protein 168) - Rat Genome Database

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Gene: Rnf168 (ring finger protein 168) Mus musculus
Analyze
Symbol: Rnf168
Name: ring finger protein 168
RGD ID: 1623959
MGI Page MGI
Description: Predicted to enable several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; histone H2AK15 ubiquitin ligase activity; and ubiquitin binding activity. Involved in isotype switching. Acts upstream of or within cellular response to UV and regulation of protein localization. Part of DNA repair complex. Is expressed in central nervous system and genitourinary system. Used to study RIDDLE syndrome. Human ortholog(s) of this gene implicated in RIDDLE syndrome. Orthologous to human RNF168 (ring finger protein 168).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 3110001H15Rik; E3 ubiquitin-protein ligase RNF168; ring fnger protein 168; RING-type E3 ubiquitin transferase RNF168
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,096,279 - 32,120,260 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,096,277 - 32,120,252 (+)EnsemblGRCm39 Ensembl
GRCm381632,277,461 - 32,301,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,277,459 - 32,301,434 (+)EnsemblGRCm38mm10GRCm38
MGSCv371632,277,547 - 32,301,528 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361632,197,236 - 32,220,653 (+)NCBIMGSCv36mm8
Celera1632,762,446 - 32,786,422 (+)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1622.51NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal cell cycle checkpoint function  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal coat/hair pigmentation  (IEA)
abnormal cornea morphology  (IEA)
abnormal cranium morphology  (IEA)
abnormal eye morphology  (IEA)
abnormal head morphology  (IEA)
abnormal heart morphology  (IEA)
abnormal lens morphology  (IEA)
abnormal Leydig cell morphology  (IAGP)
abnormal male germ cell morphology  (IAGP)
abnormal optic disk morphology  (IEA)
abnormal retina blood vessel morphology  (IEA)
abnormal retina morphology  (IEA)
abnormal retina vasculature morphology  (IEA)
abnormal skin morphology  (IEA)
abnormal snout morphology  (IEA)
abnormal spine curvature  (IEA)
abnormal spleen morphology  (IEA)
abnormal T cell receptor delta chain V(D)J recombination  (IAGP)
abnormal thymus morphology  (IEA)
anophthalmia  (IEA)
cataract  (IEA)
chromosomal instability  (IAGP)
corneal opacity  (IEA)
decreased body weight  (IEA)
decreased erythrocyte cell number  (IEA)
decreased gamma-delta T cell number  (IAGP)
decreased hematocrit  (IEA)
decreased hemoglobin content  (IEA)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG2a level  (IAGP)
decreased IgG3 level  (IAGP)
decreased litter size  (IAGP)
decreased male germ cell number  (IAGP)
decreased spleen weight  (IEA)
enlarged heart  (IEA)
enlarged thymus  (IEA)
eyelids fail to open  (IEA)
fused cornea and lens  (IEA)
increased B cell derived lymphoma incidence  (IAGP)
increased cellular sensitivity to ionizing radiation  (IAGP)
increased cellular sensitivity to ultraviolet irradiation  (IAGP)
increased circulating alanine transaminase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating creatine kinase level  (IEA)
increased circulating lactate dehydrogenase level  (IEA)
increased circulating phosphate level  (IEA)
increased DN3 thymocyte number  (IAGP)
increased double-negative T cell number  (IAGP)
increased eosinophil cell number  (IEA)
increased grip strength  (IEA)
increased hemangiosarcoma incidence  (IAGP)
increased mean platelet volume  (IEA)
increased sarcoma incidence  (IAGP)
increased thymoma incidence  (IAGP)
increased tumor incidence  (IAGP)
microphthalmia  (IEA)
narrow eye opening  (IEA)
reduced male fertility  (IAGP)
small testis  (IAGP)
testicular atrophy  (IAGP)
vertebral fusion  (IEA)
References

References - curated
# Reference Title Reference Citation
1. ATM protein kinase: the linchpin of cellular defenses to stress. Bhatti S, etal., Cell Mol Life Sci. 2011 Sep;68(18):2977-3006. doi: 10.1007/s00018-011-0683-9. Epub 2011 May 2.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Double-strand break repair: 53BP1 comes into focus. Panier S and Boulton SJ, Nat Rev Mol Cell Biol. 2014 Jan;15(1):7-18. doi: 10.1038/nrm3719. Epub 2013 Dec 11.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15489334   PMID:15618518   PMID:16141072  
PMID:16141073   PMID:18287559   PMID:18799693   PMID:20080757   PMID:21267068   PMID:21552324   PMID:21873635   PMID:22531782   PMID:23525009   PMID:24217620   PMID:24324146   PMID:24829461  
PMID:27558965   PMID:27649575   PMID:28190767   PMID:28240985   PMID:29403037   PMID:30704900   PMID:30976085   PMID:33529165   PMID:36944318  


Genomics

Comparative Map Data
Rnf168
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391632,096,279 - 32,120,260 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1632,096,277 - 32,120,252 (+)EnsemblGRCm39 Ensembl
GRCm381632,277,461 - 32,301,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1632,277,459 - 32,301,434 (+)EnsemblGRCm38mm10GRCm38
MGSCv371632,277,547 - 32,301,528 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361632,197,236 - 32,220,653 (+)NCBIMGSCv36mm8
Celera1632,762,446 - 32,786,422 (+)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1622.51NCBI
RNF168
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383196,468,783 - 196,503,768 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3196,468,783 - 196,503,768 (-)EnsemblGRCh38hg38GRCh38
GRCh373196,195,654 - 196,230,639 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,683,025 - 197,714,979 (-)NCBINCBI36Build 36hg18NCBI36
Build 343197,686,938 - 197,718,892NCBI
Celera3194,777,591 - 194,812,751 (-)NCBICelera
Cytogenetic Map3q29NCBI
HuRef3193,493,420 - 193,527,598 (-)NCBIHuRef
CHM1_13196,167,064 - 196,202,063 (-)NCBICHM1_1
T2T-CHM13v2.03199,187,976 - 199,222,947 (-)NCBIT2T-CHM13v2.0
Rnf168
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,991,352 - 82,013,306 (-)NCBIGRCr8
mRatBN7.21168,486,313 - 68,508,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,486,321 - 68,508,277 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1177,323,357 - 77,345,315 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,987,965 - 70,010,092 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,012,484 - 69,034,433 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,721,242 - 71,743,421 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,721,250 - 71,743,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01174,805,354 - 74,827,533 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41170,304,917 - 70,328,010 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1167,918,463 - 67,940,284 (-)NCBICelera
Cytogenetic Map11q22NCBI
Rnf168
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542012,657,272 - 12,676,426 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542012,656,815 - 12,676,836 (-)NCBIChiLan1.0ChiLan1.0
RNF168
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22194,336,681 - 194,375,254 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13194,341,443 - 194,379,313 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03193,814,785 - 193,848,620 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13203,755,988 - 203,791,324 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3203,756,589 - 203,790,687 (-)Ensemblpanpan1.1panPan2
RNF168
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13329,542,209 - 29,575,127 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3329,539,182 - 29,628,248 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3329,566,807 - 29,599,487 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03329,784,005 - 29,817,553 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3329,783,909 - 29,817,527 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13329,563,108 - 29,596,234 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03329,618,089 - 29,651,643 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03330,240,484 - 30,273,553 (-)NCBIUU_Cfam_GSD_1.0
Rnf168
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602124,790,716 - 124,813,795 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049367841,073,236 - 1,094,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF168
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113133,625,534 - 133,659,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNF168
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11590,702,740 - 90,735,279 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1590,702,765 - 90,737,687 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604164,501,700 - 64,536,650 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf168
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473061,591,943 - 61,627,170 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473061,592,967 - 61,627,585 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rnf168
781 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1116
Count of miRNA genes:441
Interacting mature miRNAs:519
Transcripts:ENSMUST00000014218, ENSMUST00000155649, ENSMUST00000171474
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
15092062Egrme4_mearly growth rate, maternal effect 4 (mouse)162521866444220250Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162879281362792952Mouse
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162879281362792952Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162879281362792952Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162879281362792952Mouse
25394537Skmw83_mskeletal muscle weight 83, soleus (mouse)163130446533189707Mouse
25671380Hrsq2_mhost response to SARS QTL 2, titer (mouse)163140250136540273Mouse

Markers in Region
D19428  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381632,300,824 - 32,300,917UniSTSGRCm38
MGSCv371632,300,910 - 32,301,003UniSTSGRCm37
Celera1632,785,804 - 32,785,897UniSTS
Cytogenetic Map16B2UniSTS
Whitehead_YAC16 UniSTS
D10Mit157.2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Cytogenetic Map16B4UniSTS
Cytogenetic Map18E2UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map7B2UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map11E1UniSTS
Cytogenetic Map14E2.2UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map2H4UniSTS
Cytogenetic Map1FUniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map3G2UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map9F2UniSTS
Cytogenetic Map12F1UniSTS
Cytogenetic Map19C2UniSTS
Cytogenetic Map3BUniSTS
Cytogenetic Map8C1UniSTS
Cytogenetic Map18A2UniSTS
Cytogenetic Map3F2UniSTS
Cytogenetic Map14C3UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map8E2UniSTS
Cytogenetic Map5B1UniSTS
Cytogenetic Map18B1UniSTS
Cytogenetic Map9CUniSTS
Cytogenetic Map14C2UniSTS
Cytogenetic Map6A1UniSTS
Cytogenetic Map10B4UniSTS
Cytogenetic Map13D2.1UniSTS
Cytogenetic Map5E5UniSTS
Cytogenetic Map11B1.3UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map9A5.2UniSTS
Cytogenetic Map3F1UniSTS
Cytogenetic Map17E3UniSTS
Cytogenetic Map11B3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map6A3UniSTS
Cytogenetic Map5E4-E5UniSTS
Cytogenetic Map15E1UniSTS
Cytogenetic Map13DUniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map14D1UniSTS
Cytogenetic Map7B4UniSTS
Cytogenetic Map8D3UniSTS
Cytogenetic MapXDUniSTS
Cytogenetic Map17A3.3UniSTS
Cytogenetic Map7E2UniSTS
Cytogenetic Map1H2.3UniSTS
Cytogenetic Map7A2UniSTS
Cytogenetic Map7F3UniSTS
Cytogenetic Map9F1UniSTS
Cytogenetic Map10C1UniSTS
Cytogenetic Map4E2UniSTS
Cytogenetic Map16A1UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map8D2UniSTS
Cytogenetic Map3DUniSTS
Cytogenetic Map15D2UniSTS
Cytogenetic Map17B1UniSTS
Cytogenetic Map7A3UniSTS
Cytogenetic Map15F1UniSTS
Cytogenetic Map16B2UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map6F3UniSTS
Cytogenetic Map1C4UniSTS
Cytogenetic Map11E2UniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic Map9F3UniSTS
Cytogenetic Map2BUniSTS
Cytogenetic Map13B3UniSTS
Cytogenetic Map9A4UniSTS
Cytogenetic Map5A3UniSTS
Cytogenetic Map2H1UniSTS
Cytogenetic Map16B1UniSTS
Cytogenetic Map1A5UniSTS
Cytogenetic Map11CUniSTS
Cytogenetic Map9E1UniSTS
Cytogenetic Map6G1UniSTS
Cytogenetic MapXA2UniSTS
Cytogenetic Map13B1UniSTS
Cytogenetic Map5E2UniSTS
Cytogenetic Map12C1UniSTS
Cytogenetic Map5FUniSTS
Cytogenetic Map4D3UniSTS
Cytogenetic Map10C2UniSTS
Cytogenetic Map9BUniSTS
Cytogenetic Map5G2UniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map12C3UniSTS
Cytogenetic Map10A4UniSTS
Cytogenetic Map8A2UniSTS
Cytogenetic Map18A1UniSTS
Cytogenetic Map12A1.1UniSTS
Cytogenetic Map1C2UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map5C3.3UniSTS
Cytogenetic Map1BUniSTS
Cytogenetic Map17A3.1UniSTS
Cytogenetic Map7A1UniSTS
Cytogenetic Map2E5UniSTS
Cytogenetic Map11A1UniSTS
Cytogenetic Map4B1UniSTS
Cytogenetic Map15A2UniSTS
Cytogenetic Map8C3UniSTS
Cytogenetic Map2A3UniSTS
Cytogenetic Map5G3UniSTS
Cytogenetic Map4A3UniSTS
Cytogenetic Map2H3UniSTS
Cytogenetic Map8A1UniSTS
Cytogenetic Map8A1.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic Map10B1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map4A1UniSTS
Cytogenetic Map9A3UniSTS
Cytogenetic Map17CUniSTS
Cytogenetic Map1DUniSTS
Cytogenetic Map5E3UniSTS
Cytogenetic Map15D3UniSTS
Cytogenetic Map2H2UniSTS
Cytogenetic Map7D3UniSTS
Cytogenetic Map2A1UniSTS
Cytogenetic Map14C1UniSTS
Cytogenetic Map14E5UniSTS
Cytogenetic Map10CUniSTS
Cytogenetic Map18B2UniSTS
Cytogenetic Map2F1UniSTS
Cytogenetic Map10D3UniSTS
Cytogenetic Map17A2UniSTS
Cytogenetic Map2C3UniSTS
Cytogenetic Map1C3UniSTS
Cytogenetic Map17B2UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map5G1UniSTS
Cytogenetic Map4C6UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map2E1UniSTS
Cytogenetic Map17A3.2-A3.3UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map9E3.1UniSTS
Cytogenetic Map15E3UniSTS
Cytogenetic Map6B1UniSTS
Cytogenetic MapXE3UniSTS
Cytogenetic Map4C4UniSTS
Cytogenetic Map3E3UniSTS
Cytogenetic Map11A4UniSTS
Cytogenetic Map4C5UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map9A2UniSTS
Cytogenetic Map7E1UniSTS
Cytogenetic Map5D-E1UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map13A2-A3UniSTS
Cytogenetic Map5A2UniSTS
Cytogenetic Map4B3UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map17E4UniSTS
Cytogenetic Map1G2UniSTS
Cytogenetic Map15B3.1UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic MapXA5UniSTS
Cytogenetic Map6A3.3UniSTS
Cytogenetic Map6G3UniSTS
Cytogenetic Map6F2UniSTS
Cytogenetic Map5C1UniSTS
Cytogenetic Map4D2.1UniSTS
Cytogenetic Map4A5UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map1E3-E4UniSTS
Cytogenetic Map9F1-F3UniSTS
Cytogenetic Map1C1.1UniSTS
Cytogenetic Map14D2UniSTS
Cytogenetic Map12A2UniSTS
Cytogenetic Map17A3-BUniSTS
Cytogenetic Map7F5UniSTS
Cytogenetic Map14A3UniSTS
Cytogenetic Map5G1.1UniSTS
Cytogenetic MapXF2-F4UniSTS
Cytogenetic Map7D2UniSTS
Cytogenetic Map2F3UniSTS
Cytogenetic Map10A3UniSTS
Cytogenetic MapXA7.3UniSTS
Cytogenetic Map9F1-F2UniSTS
Cytogenetic Map13A3.2UniSTS
Cytogenetic Map10A2UniSTS
Cytogenetic Map1C1UniSTS
Cytogenetic Map1A1UniSTS
Cytogenetic Map12D3UniSTS
Cytogenetic Map1A3-A5UniSTS
Cytogenetic Map2A2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic MapXA3.3UniSTS
Cytogenetic Map16A-B1UniSTS
Cytogenetic Map1D2.3UniSTS
Cytogenetic Map6B2.3UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic MapXA2-A3.1UniSTS
Cytogenetic Map9A5.3UniSTS
Cytogenetic Map14A2-BUniSTS
Cytogenetic Map8E1-E2UniSTS
Cytogenetic Map8A3UniSTS
Cytogenetic Map1G3-H1UniSTS
Cytogenetic Map8B3-C1UniSTS
Cytogenetic Map19C1UniSTS
Cytogenetic Map8C5UniSTS
Cytogenetic Map8A4UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map14E4UniSTS
Cytogenetic Map4D2.2UniSTS
Cytogenetic MapXF5UniSTS
cM Map1040.0UniSTS
Whitehead Genetic1033.9UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000014218   ⟹   ENSMUSP00000014218
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1632,096,279 - 32,119,724 (+)Ensembl
GRCm38.p6 Ensembl1632,277,461 - 32,300,906 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155649
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1632,096,277 - 32,108,012 (+)Ensembl
GRCm38.p6 Ensembl1632,277,459 - 32,289,194 (+)Ensembl
RefSeq Acc Id: ENSMUST00000171474   ⟹   ENSMUSP00000126484
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1632,096,279 - 32,120,252 (+)Ensembl
GRCm38.p6 Ensembl1632,277,461 - 32,301,434 (+)Ensembl
RefSeq Acc Id: NM_027355   ⟹   NP_081631
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391632,096,279 - 32,120,260 (+)NCBI
GRCm381632,277,461 - 32,301,442 (+)ENTREZGENE
MGSCv371632,277,547 - 32,301,528 (+)RGD
Celera1632,762,446 - 32,786,422 (+)RGD
cM Map16 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_081631   ⟸   NM_027355
- UniProtKB: Q80XJ2 (UniProtKB/Swiss-Prot),   E9PYW4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000014218   ⟸   ENSMUST00000014218
RefSeq Acc Id: ENSMUSP00000126484   ⟸   ENSMUST00000171474
Protein Domains
RING-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80XJ2-F1-model_v2 AlphaFold Q80XJ2 1-565 view protein structure

Promoters
RGD ID:6827417
Promoter ID:MM_KWN:20753
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_027355,   OTTMUST00000063482
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361632,276,786 - 32,278,117 (+)MPROMDB
RGD ID:8685980
Promoter ID:EPDNEW_M21021
Type:initiation region
Name:Rnf168_1
Description:Mus musculus ring finger protein 168 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21022  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381632,277,503 - 32,277,563EPDNEW
RGD ID:8685982
Promoter ID:EPDNEW_M21022
Type:single initiation site
Name:Rnf168_2
Description:Mus musculus ring finger protein 168 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21021  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381632,277,650 - 32,277,710EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917488 AgrOrtholog
Ensembl Genes ENSMUSG00000014074 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000014218.15 UniProtKB/Swiss-Prot
  ENSMUST00000171474 ENTREZGENE
  ENSMUST00000171474.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RNF168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:70238 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917488 ENTREZGENE
NCBI Gene 70238 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Prok-RING_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rnf168 PhenoGen
PROSITE ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9PYW4 ENTREZGENE, UniProtKB/TrEMBL
  Q80XJ2 ENTREZGENE
  Q8BPM3_MOUSE UniProtKB/TrEMBL
  Q9CRX7_MOUSE UniProtKB/TrEMBL
  RN168_MOUSE UniProtKB/Swiss-Prot