Pcgf1 (polycomb group ring finger 1) - Rat Genome Database
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Gene: Pcgf1 (polycomb group ring finger 1) Mus musculus
Analyze
Symbol: Pcgf1
Name: polycomb group ring finger 1
RGD ID: 1557454
MGI Page MGI
Description: Is expressed in several structures, including adrenal gland; cardiac muscle tissue; genitourinary system; nervous system; and otocyst. Orthologous to human PCGF1 (polycomb group ring finger 1); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010002K04Rik; AU024121; nervous system polycomb 1; nervous system Polycomb-1; Ns; Nspc1; polycomb group RING finger protein 1; RING finger protein 68
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8930  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,054,173 - 83,057,836 (+)NCBIGRCm39mm39
GRCm39 Ensembl683,054,850 - 83,057,836 (+)Ensembl
GRCm38683,077,552 - 83,080,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,077,869 - 83,080,855 (+)EnsemblGRCm38mm10GRCm38
MGSCv37683,028,384 - 83,030,849 (+)NCBIGRCm37mm9NCBIm37
MGSCv36683,044,048 - 83,046,513 (+)NCBImm8
Celera685,060,962 - 85,063,427 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (ISO)
nucleus  (IDA,ISO)
PcG protein complex  (IDA,ISO)
PRC1 complex  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11287196   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17296600   PMID:18287559  
PMID:21267068   PMID:21677750   PMID:21873635   PMID:22174793   PMID:22325148   PMID:22411870   PMID:23395003   PMID:24113379   PMID:24194600   PMID:24457600   PMID:26496610   PMID:27705745  
PMID:28393894   PMID:28596365   PMID:29727681  


Genomics

Comparative Map Data
Pcgf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39683,054,173 - 83,057,836 (+)NCBIGRCm39mm39
GRCm39 Ensembl683,054,850 - 83,057,836 (+)Ensembl
GRCm38683,077,552 - 83,080,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl683,077,869 - 83,080,855 (+)EnsemblGRCm38mm10GRCm38
MGSCv37683,028,384 - 83,030,849 (+)NCBIGRCm37mm9NCBIm37
MGSCv36683,044,048 - 83,046,513 (+)NCBImm8
Celera685,060,962 - 85,063,427 (+)NCBICelera
Cytogenetic Map6C3NCBI
cM Map635.94NCBI
PCGF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl274,505,043 - 74,507,695 (-)EnsemblGRCh38hg38GRCh38
GRCh38274,505,043 - 74,507,695 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37274,732,170 - 74,734,822 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36274,585,678 - 74,588,329 (-)NCBINCBI36hg18NCBI36
Build 34274,643,825 - 74,646,441NCBI
Celera274,563,334 - 74,565,985 (-)NCBI
Cytogenetic Map2p13.1NCBI
HuRef274,468,431 - 74,471,082 (-)NCBIHuRef
CHM1_1274,661,580 - 74,664,231 (-)NCBICHM1_1
Pcgf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24115,576,165 - 115,587,019 (+)NCBI
Rnor_6.0 Ensembl4113,910,685 - 113,913,687 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04113,911,129 - 113,913,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04178,596,101 - 178,598,690 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,290,410 - 117,292,999 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4104,578,940 - 104,581,529 (+)NCBICelera
Cytogenetic Map4q34NCBI
Pcgf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542411,282,091 - 11,286,753 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542411,282,562 - 11,284,970 (+)NCBIChiLan1.0ChiLan1.0
PCGF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A76,077,962 - 76,080,714 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A76,077,962 - 76,080,720 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A74,571,721 - 74,574,468 (-)NCBIMhudiblu_PPA_v0panPan3
PCGF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1748,633,332 - 48,635,554 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11748,633,207 - 48,642,435 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Pcgf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936556719,601 - 722,339 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCGF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1368,540,674 - 68,543,271 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2371,865,575 - 71,868,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PCGF1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11432,769,805 - 32,772,806 (+)NCBI
ChlSab1.1 Ensembl1432,770,492 - 32,772,804 (+)Ensembl
Pcgf1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474928,999,506 - 29,007,744 (+)NCBI

Position Markers
AU024121  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38622,734,383 - 22,734,468UniSTSGRCm38
GRCm38683,080,563 - 83,080,727UniSTSGRCm38
MGSCv37622,684,383 - 22,684,468UniSTSGRCm37
MGSCv37683,030,557 - 83,030,721UniSTSGRCm37
Celera685,063,135 - 85,063,299UniSTS
Celera622,781,756 - 22,781,841UniSTS
Cytogenetic Map6C3UniSTS
Cytogenetic Map6A3.1UniSTS
cM Map635.0UniSTS
Whitehead/MRC_RH6850.27UniSTS
RH99023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38622,734,242 - 22,734,386UniSTSGRCm38
MGSCv37622,684,242 - 22,684,386UniSTSGRCm37
Celera622,781,615 - 22,781,759UniSTS
Cytogenetic Map6A3.1UniSTS
Cytogenetic Map6C3UniSTS
cM Map635.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65117915085179300Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
4141990Etax6_methanol induced ataxia 6 (mouse)Not determined7132262186275719Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1281
Count of miRNA genes:490
Interacting mature miRNAs:549
Transcripts:ENSMUST00000092614, ENSMUST00000165164, ENSMUST00000176027, ENSMUST00000176089, ENSMUST00000176100, ENSMUST00000176372, ENSMUST00000177177
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000092614   ⟹   ENSMUSP00000090277
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,078,390 - 83,080,847 (+)Ensembl
RefSeq Acc Id: ENSMUST00000165164   ⟹   ENSMUSP00000130614
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,078,346 - 83,080,855 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176027   ⟹   ENSMUSP00000135664
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,078,630 - 83,080,757 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176089   ⟹   ENSMUSP00000135268
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,078,691 - 83,080,757 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176100   ⟹   ENSMUSP00000135882
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,077,869 - 83,078,995 (+)Ensembl
RefSeq Acc Id: ENSMUST00000176372
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,080,020 - 83,080,854 (+)Ensembl
RefSeq Acc Id: ENSMUST00000177177   ⟹   ENSMUSP00000135291
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,078,630 - 83,080,854 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204211
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl683,078,718 - 83,079,710 (+)Ensembl
RefSeq Acc Id: NM_197992   ⟹   NP_932109
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,055,371 - 83,057,836 (+)NCBI
GRCm38683,078,390 - 83,080,855 (+)ENTREZGENE
MGSCv37683,028,384 - 83,030,849 (+)RGD
Celera685,060,962 - 85,063,427 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030255588   ⟹   XP_030111448
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39683,054,173 - 83,057,836 (+)NCBI
GRCm38683,077,552 - 83,080,855 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_932109 (Get FASTA)   NCBI Sequence Viewer  
  XP_030111448 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH28560 (Get FASTA)   NCBI Sequence Viewer  
  Q8R023 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_932109   ⟸   NM_197992
- UniProtKB: Q8R023 (UniProtKB/Swiss-Prot),   A0A0R4J141 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111448   ⟸   XM_030255588
- Peptide Label: isoform X1
RefSeq Acc Id: ENSMUSP00000135291   ⟸   ENSMUST00000177177
RefSeq Acc Id: ENSMUSP00000090277   ⟸   ENSMUST00000092614
RefSeq Acc Id: ENSMUSP00000130614   ⟸   ENSMUST00000165164
RefSeq Acc Id: ENSMUSP00000135664   ⟸   ENSMUST00000176027
RefSeq Acc Id: ENSMUSP00000135268   ⟸   ENSMUST00000176089
RefSeq Acc Id: ENSMUSP00000135882   ⟸   ENSMUST00000176100
Protein Domains
RAWUL   RING-type

Promoters
RGD ID:6839731
Promoter ID:MM_KWN:46568
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_197992,   UC009CMH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36683,027,736 - 83,028,552 (+)MPROMDB
RGD ID:6890122
Promoter ID:EPDNEW_M8511
Type:initiation region
Name:Pcgf1_1
Description:Mus musculus polycomb group ring finger 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8512  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38683,078,379 - 83,078,439EPDNEW
RGD ID:6890124
Promoter ID:EPDNEW_M8512
Type:initiation region
Name:Pcgf1_2
Description:Mus musculus polycomb group ring finger 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8511  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38683,078,626 - 83,078,686EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1917087 AgrOrtholog
Ensembl Genes ENSMUSG00000069678 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000090277 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000130614 UniProtKB/Swiss-Prot
  ENSMUSP00000135268 UniProtKB/TrEMBL
  ENSMUSP00000135291 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000135664 UniProtKB/TrEMBL
  ENSMUSP00000135882 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000092614 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000165164 UniProtKB/Swiss-Prot
  ENSMUST00000176027 UniProtKB/TrEMBL
  ENSMUST00000176089 UniProtKB/TrEMBL
  ENSMUST00000176100 UniProtKB/TrEMBL
  ENSMUST00000177177 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RAWUL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
  Znf_RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:69837 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1917087 ENTREZGENE
NCBI Gene 69837 ENTREZGENE
Pfam RAWUL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pcgf1 PhenoGen
PROSITE ZF_RING_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A0R4J141 ENTREZGENE, UniProtKB/TrEMBL
  H3BK63_MOUSE UniProtKB/TrEMBL
  H3BK85_MOUSE UniProtKB/TrEMBL
  H3BL61_MOUSE UniProtKB/TrEMBL
  H3BLR0_MOUSE UniProtKB/TrEMBL
  PCGF1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE