Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of AGO3 mRNA | CTD | PMID:28189721 and PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of AGO3 mRNA | CTD | PMID:22206623 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | AGO3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AGO3 mRNA | CTD | PMID:21354282 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of AGO3 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of AGO3 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of AGO3 mRNA | CTD | PMID:22298810 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,4,6-tribromophenol | decreases expression | ISO | AGO3 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | AGO3 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of AGO3 protein | CTD | PMID:31675489 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AGO3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AGO3 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AGO3 mRNA | CTD | PMID:28628672 | 4-hydroxynon-2-enal | decreases expression | EXP | | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of AGO3 mRNA | CTD | PMID:19191707 | 4-hydroxynon-2-enal | increases expression | EXP | | 6480464 | 4-hydroxy-2-nonenal results in increased expression of AGO3 mRNA | CTD | PMID:19191707 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of AGO3 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | ISO | AGO3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of AGO3 exon | CTD | PMID:30157460 | aflatoxin B1 | decreases methylation | ISO | AGO3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of AGO3 gene | CTD | PMID:27153756 | arsenite(3-) | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to AGO3 mRNA] | CTD | PMID:32406909 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of AGO3 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of AGO3 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | AGO3 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | bisphenol A | decreases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of AGO3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of AGO3 mRNA | CTD | PMID:32156529 and PMID:38074096 | bisphenol A | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AGO3 mRNA | CTD | PMID:28628672 | bisphenol A | increases methylation | ISO | Ago3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of AGO3 gene | CTD | PMID:28505145 | carbamazepine | affects expression | ISO | AGO3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of AGO3 mRNA | CTD | PMID:24752500 | cisplatin | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of AGO3 mRNA | CTD | PMID:27392435 | cycloheximide | multiple interactions | EXP | | 6480464 | Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] | CTD | PMID:29576526 | cyclosporin A | increases expression | ISO | AGO3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of AGO3 mRNA | CTD | PMID:25562108 | decabromodiphenyl ether | decreases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | decabromobiphenyl ether results in decreased expression of AGO3 mRNA | CTD | PMID:23640034 | decabromodiphenyl ether | decreases expression | ISO | AGO3 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of AGO3 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AGO3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AGO3 mRNA | CTD | PMID:28628672 | diclofenac | affects expression | ISO | AGO3 (Homo sapiens) | 6480464 | Diclofenac affects the expression of AGO3 mRNA | CTD | PMID:24752500 | emetine | multiple interactions | EXP | | 6480464 | Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] | CTD | PMID:29576526 | fulvestrant | affects methylation | ISO | AGO3 (Homo sapiens) | 6480464 | Fulvestrant affects the methylation of AGO3 gene | CTD | PMID:31601247 | gentamycin | increases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of AGO3 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | AGO3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of AGO3 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of AGO3 mRNA | CTD | PMID:28628672 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AGO3 mRNA | CTD | PMID:36331819 | maneb | multiple interactions | EXP | | 6480464 | [Paraquat co-treated with Maneb] affects the expression of AGO3 mRNA | CTD | PMID:22563483 | methyl methanesulfonate | increases expression | ISO | AGO3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of AGO3 mRNA | CTD | PMID:23649840 | paracetamol | increases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of AGO3 mRNA | CTD | PMID:33387578 | paraquat | multiple interactions | EXP | | 6480464 | [Paraquat co-treated with Maneb] affects the expression of AGO3 mRNA | CTD | PMID:22563483 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of AGO3 mRNA | CTD | PMID:22563483 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AGO3 mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of AGO3 mRNA | CTD | PMID:23091169 | potassium dichromate | decreases expression | ISO | AGO3 (Homo sapiens) | 6480464 | Potassium Dichromate results in decreased expression of AGO3 protein | CTD | PMID:23718831 | pyridaben | increases expression | EXP | | 6480464 | pyridaben results in increased expression of AGO3 mRNA | CTD | PMID:22563483 | silver atom | increases expression | EXP | | 6480464 | Silver results in increased expression of AGO3 mRNA | CTD | PMID:27131904 | silver atom | affects expression | EXP | | 6480464 | Silver affects the expression of AGO3 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | EXP | | 6480464 | Silver results in increased expression of AGO3 mRNA | CTD | PMID:27131904 | silver(0) | affects expression | EXP | | 6480464 | Silver affects the expression of AGO3 mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | EXP | | 6480464 | sodium arsenate results in increased expression of AGO3 mRNA | CTD | PMID:21795629 | sodium fluoride | decreases expression | EXP | | 6480464 | Sodium Fluoride results in decreased expression of AGO3 mRNA | CTD | PMID:27862939 | sunitinib | increases expression | ISO | AGO3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of AGO3 mRNA | CTD | PMID:31533062 | testosterone enanthate | affects expression | ISO | AGO3 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of AGO3 mRNA | CTD | PMID:17440010 | thapsigargin | affects localization | EXP | | 6480464 | Thapsigargin affects the localization of AGO3 mRNA | CTD | PMID:29576526 | thapsigargin | multiple interactions | EXP | | 6480464 | Cycloheximide inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] and Emetine inhibits the reaction [Thapsigargin affects the localization of AGO3 mRNA] | CTD | PMID:29576526 | thioacetamide | increases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of AGO3 mRNA | CTD | PMID:23411599 | urethane | increases expression | ISO | AGO3 (Homo sapiens) | 6480464 | Urethane results in increased expression of AGO3 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | AGO3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of AGO3 mRNA | CTD | PMID:29154799 | valproic acid | affects splicing | ISO | Ago3 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of AGO3 mRNA | CTD | PMID:29427782 | valproic acid | decreases expression | ISO | Ago3 (Rattus norvegicus) | 6480464 | Valproic Acid results in decreased expression of AGO3 mRNA | CTD | PMID:29427782 | |