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Gene: Iqgap1 (IQ motif containing GTPase activating protein 1) Mus musculus
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Symbol: Iqgap1
Name: IQ motif containing GTPase activating protein 1
Description: Exhibits Rac GTPase binding activity. Involved in several processes, including cellular response to growth factor stimulus; regulation of phosphate metabolic process; and transmembrane receptor protein tyrosine kinase signaling pathway. Localizes to several cellular components, including cell leading edge; focal adhesion; and lateral plasma membrane. Predicted to colocalize with actin cytoskeleton and microtubule cytoskeleton. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and skin. Orthologous to human IQGAP1 (IQ motif containing GTPase activating protein 1); PARTICIPATES IN E-cadherin signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA682088; Cdc42-Rac1 effector protein; D7Ertd237e; D7Ertd257e; mKIAA0051; ras GTPase-activating-like protein IQGAP1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl780,711,583 - 80,825,974 (-)EnsemblGRCm38mm10GRCm38
GRCm38780,711,583 - 80,815,549 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37787,856,469 - 87,948,217 (-)NCBIGRCm37mm9NCBIm37
MGSCv36780,586,294 - 80,676,807 (-)NCBImm8
Celera778,116,162 - 78,211,858 (-)NCBICelera
Cytogenetic Map7D3NCBI
cM Map745.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Iqgap1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323574
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.