Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Fgfr1 (fibroblast growth factor receptor 1) Mus musculus
Analyze
Symbol: Fgfr1
Name: fibroblast growth factor receptor 1
Description: Exhibits SH2 domain binding activity; fibroblast growth factor binding activity; and fibroblast growth factor-activated receptor activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of animal organ morphogenesis. Localizes to the plasma membrane. Used to study Pfeiffer syndrome and otitis media. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; acrocephalosyndactylia (multiple); cleft lip; hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human FGFR1 (fibroblast growth factor receptor 1); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; INTERACTS WITH (S)-amphetamine; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW208770; basic fibroblast growth factor receptor 1; bFGF-R-1; c-fgr; Eask; Fgfr-1; FGFR-I; FLG; Flt-2; Fr1; Hspy; MFR; proto-oncogene c-Fgr
Orthologs:
Homo sapiens (human) : FGFR1 (fibroblast growth factor receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgfr1 (Fibroblast growth factor receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr1 (fibroblast growth factor receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR1 (fibroblast growth factor receptor 1)
Canis lupus familiaris (dog) : FGFR1 (fibroblast growth factor receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr1 (fibroblast growth factor receptor 1)
Sus scrofa (pig) : FGFR1 (fibroblast growth factor receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38825,518,759 - 25,575,718 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37826,629,244 - 26,686,186 (+)NCBIGRCm37mm9NCBIm37
MGSCv36826,997,826 - 27,039,466 (+)NCBImm8
Celera826,986,809 - 27,044,078 (+)NCBICelera
Cytogenetic Map8 A2NCBI
cM Map814.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fgfr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732291
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.