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Gene: Fgfr1 (fibroblast growth factor receptor 1) Mus musculus
Symbol: Fgfr1
Name: fibroblast growth factor receptor 1
Description: Exhibits SH2 domain binding activity; fibroblast growth factor binding activity; and fibroblast growth factor-activated receptor activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of animal organ morphogenesis. Localizes to the plasma membrane. Used to study Pfeiffer syndrome and otitis media. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; acrocephalosyndactylia (multiple); cleft lip; hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human FGFR1 (fibroblast growth factor receptor 1); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; INTERACTS WITH (S)-amphetamine; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW208770; basic fibroblast growth factor receptor 1; bFGF-R-1; c-fgr; Eask; Fgfr-1; FGFR-I; FLG; Flt-2; Fr1; Hspy; MFR; proto-oncogene c-Fgr
Homo sapiens (human) : FGFR1 (fibroblast growth factor receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fgfr1 (Fibroblast growth factor receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr1 (fibroblast growth factor receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR1 (fibroblast growth factor receptor 1)
Canis lupus familiaris (dog) : FGFR1 (fibroblast growth factor receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr1 (fibroblast growth factor receptor 1)
Sus scrofa (pig) : FGFR1 (fibroblast growth factor receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38825,518,759 - 25,575,718 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37826,629,244 - 26,686,186 (+)NCBIGRCm37mm9NCBIm37
MGSCv36826,997,826 - 27,039,466 (+)NCBImm8
Celera826,986,809 - 27,044,078 (+)NCBICelera
Cytogenetic Map8 A2NCBI
cM Map814.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Fgfr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732291
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.