Fgfr1 (fibroblast growth factor receptor 1) - Rat Genome Database
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Gene: Fgfr1 (fibroblast growth factor receptor 1) Mus musculus
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Symbol: Fgfr1
Name: fibroblast growth factor receptor 1
RGD ID: 732291
MGI Page MGI
Description: Exhibits SH2 domain binding activity; fibroblast growth factor binding activity; and fibroblast growth factor-activated receptor activity. Involved in several processes, including animal organ development; positive regulation of cell population proliferation; and regulation of animal organ morphogenesis. Localizes to plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study Pfeiffer syndrome and otitis media. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; bone disease (multiple); cleft lip; hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Orthologous to human FGFR1 (fibroblast growth factor receptor 1); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; INTERACTS WITH (S)-amphetamine; 1,1-dichloroethene; 1,2-dichloroethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW208770; basic fibroblast growth factor receptor 1; bFGF-R-1; c-fgr; Ea; Eask; FGFR; Fgfr-; Fgfr-1; FGFR-I; FLG; Flt-; Flt-2; Fr; Fr1; Hs; Hspy; MFR; proto-oncogene c-Fgr
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,008,775 - 26,065,734 (+)NCBIGRCm39mm39
GRCm38825,518,759 - 25,575,718 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,513,654 - 25,575,718 (+)EnsemblGRCm38mm10GRCm38
MGSCv37826,629,244 - 26,686,186 (+)NCBIGRCm37mm9NCBIm37
MGSCv36826,997,826 - 27,039,466 (+)NCBImm8
Celera826,986,822 - 27,044,074 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map814.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (ISO)
acrocephalosyndactylia  (ISO)
Acute Lymphoblastic Leukemia, with Lymphomatous Features  (ISO)
acute myeloid leukemia  (ISO)
Alzheimer's disease  (ISO)
astrocytoma  (ISO)
atypical chronic myeloid leukemia  (ISO)
autistic disorder  (ISO)
Breast Neoplasms  (ISO)
Burns  (ISO)
cerebellar hypoplasia  (ISO)
cleft lip  (ISO)
cleft palate  (ISO)
Congenital Foot Deformities  (ISO)
Craniofacial Abnormalities  (IMP,ISO)
craniosynostosis  (IMP,ISO)
Delayed Puberty  (ISO)
demyelinating disease  (IEP)
disease of cellular proliferation  (ISO)
Encephalocraniocutaneous Lipomatosis  (ISO)
Experimental Arthritis  (IMP)
Experimental Leukemia  (ISO)
Experimental Liver Cirrhosis  (ISO)
fatty liver disease  (ISO)
Femoral Fractures  (ISO)
fibrolamellar carcinoma  (ISO)
gastric adenocarcinoma  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
Head Injuries, Penetrating  (ISO)
heart valve disease  (ISO)
hepatocellular carcinoma  (ISO)
holoprosencephaly  (ISO)
Holoprosencephaly, Ectrodactyly, and Bilateral Cleft Lip/Palate  (ISO)
Hypoglossal Nerve Injuries  (ISO)
hypogonadotropic hypogonadism 2 with or without anosmia  (ISO)
hypogonadotropic hypogonadism 7 with or without anosmia  (ISO)
Hypogonadotropic Hypogonadism and Anosmia, Autosomal Dominant  (ISO)
Jackson-Weiss syndrome  (ISO)
Kallmann syndrome  (ISO)
Limb Ischemia  (ISO)
Liver Metastasis  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
malignant glioma  (ISO)
medulloblastoma  (ISO)
mental depression  (ISO)
mesangial proliferative glomerulonephritis  (ISO)
mouth disease  (ISO)
myeloid leukemia  (ISO)
myeloid neoplasm  (ISO)
myocardial infarction  (IEP)
Neointima  (ISO)
Neoplasm Metastasis  (IMP)
neuroblastoma  (ISO)
non-alcoholic fatty liver disease  (IEP)
Nonsyndromic Trigonocephaly  (ISO)
obesity  (ISO)
osteoarthritis  (ISO)
Osteoarthritis, Experimental  (IMP)
osteoglophonic dysplasia  (ISO)
otitis media  (IEA)
Pfeiffer syndrome  (IEA,ISO)
prostate adenocarcinoma  (IDA,IEP)
prostate cancer  (ISO)
prostate carcinoma in situ  (IDA)
pulmonary hypertension  (ISO)
renal cell carcinoma  (ISO)
retinal detachment  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (ISO)
squamous cell carcinoma  (ISO)
Stargardt Disease 3  (IEP)
T-Cell Lymphoma  (ISO)
Talipes Cavus  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
Trigonocephaly 1  (ISO)
Tympanic Membrane Perforation  (ISO)
type 2 diabetes mellitus  (IMP)
umbilical hernia  (IMP)
vascular dementia  (ISO)
visual epilepsy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (EXP)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B2  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
AP20187  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-D-glucosamine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
chlorpromazine  (ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) chloride  (ISO)
coumestrol  (ISO)
crizotinib  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
dieldrin  (ISO)
dimethylarsinous acid  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ellagic acid  (ISO)
entinostat  (ISO)
enzacamene  (ISO)
ethanol  (EXP,ISO)
ethyl trans-caffeate  (ISO)
fenamidone  (EXP)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
furan  (ISO)
gamma-tocopherol  (ISO)
heparan sulfate  (EXP,ISO)
heparin  (EXP,ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
isotretinoin  (ISO)
kainic acid  (ISO)
L-methionine  (EXP)
lead diacetate  (ISO)
lenalidomide  (ISO)
malathion  (ISO)
methotrexate  (ISO)
methylmercury chloride  (EXP,ISO)
morphine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
orantinib  (ISO)
oxaliplatin  (ISO)
paracetamol  (ISO)
paraoxon  (ISO)
PD-166866  (ISO)
PD173074  (ISO)
peroxynitrous acid  (ISO)
piperine  (ISO)
pirinixic acid  (ISO)
pomalidomide  (ISO)
ponatinib  (ISO)
resveratrol  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
taurine  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
thalidomide  (ISO)
titanium dioxide  (EXP)
tocopherol  (ISO)
topotecan  (ISO)
urea  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc protoporphyrin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IGI)
auditory receptor cell development  (IMP)
blood vessel morphogenesis  (IMP)
brain development  (IMP)
branching involved in salivary gland morphogenesis  (IMP)
cell maturation  (IMP)
cellular response to histamine  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
central nervous system neuron development  (ISO)
chondrocyte differentiation  (IGI)
ear development  (IMP)
embryonic limb morphogenesis  (IMP)
epithelial to mesenchymal transition  (ISO)
female pregnancy  (ISO)
fibroblast growth factor receptor signaling pathway  (IGI,ISO)
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development  (IMP)
generation of neurons  (IMP)
in utero embryonic development  (IGI)
inner ear morphogenesis  (IMP)
lung development  (IGI,IMP)
lung-associated mesenchyme development  (IGI)
mesenchymal cell differentiation  (IGI)
midbrain development  (IGI,IMP)
middle ear morphogenesis  (IMP)
motogenic signaling involved in postnatal olfactory bulb interneuron migration  (ISO)
multicellular organism development  (IBA)
negative regulation of fibroblast growth factor production  (IGI)
negative regulation of gene expression  (IGI,IMP)
negative regulation of osteoblast differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (IMP)
neuron projection development  (ISO)
orbitofrontal cortex development  (IMP)
organ induction  (IMP)
outer ear morphogenesis  (IMP)
paraxial mesoderm development  (IGI)
peptidyl-tyrosine phosphorylation  (ISO)
phosphorylation  (IEA)
positive regulation of blood vessel endothelial cell migration  (ISO)
positive regulation of cardiac muscle cell proliferation  (IGI,ISO)
positive regulation of cell cycle  (IMP)
positive regulation of cell differentiation  (IBA)
positive regulation of cell population proliferation  (IDA,IGI,IMP,ISO,TAS)
positive regulation of endothelial cell chemotaxis to fibroblast growth factor  (ISO)
positive regulation of fibroblast migration  (ISO)
positive regulation of hepatic stellate cell activation  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of kinase activity  (IBA)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway  (IGI)
positive regulation of mesenchymal cell proliferation  (IGI,IMP,ISO)
positive regulation of mitotic cell cycle DNA replication  (IDA)
positive regulation of neuron differentiation  (ISO)
positive regulation of neuron projection development  (IGI,ISO)
positive regulation of parathyroid hormone secretion  (IGI)
positive regulation of phospholipase C activity  (ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of vascular endothelial cell proliferation  (ISO)
protein autophosphorylation  (ISO)
protein phosphorylation  (IEA)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  (IDA)
regulation of cell population proliferation  (IMP,ISO)
regulation of extrinsic apoptotic signaling pathway in absence of ligand  (IMP)
regulation of gene expression  (IMP)
regulation of lateral mesodermal cell fate specification  (IGI)
regulation of phosphate transport  (IGI)
regulation of phosphorus metabolic process  (IGI)
regulation of sensory perception of pain  (ISO)
regulation of stem cell proliferation  (ISO)
response to ischemia  (ISO)
response to nutrient levels  (ISO)
salivary gland morphogenesis  (IMP)
sensory perception of sound  (IMP)
stem cell population maintenance  (ISO)
transmembrane receptor protein tyrosine kinase signaling pathway  (IBA)
ureteric bud development  (IGI)
vasculogenesis involved in coronary vascular morphogenesis  (TAS)
ventricular zone neuroblast division  (IMP)
vitamin D3 metabolic process  (IGI)
wound healing  (ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal alisphenoid bone morphology  (IAGP)
abnormal apical ectodermal ridge morphology  (IAGP)
abnormal astrocyte morphology  (IAGP)
abnormal auditory bulla morphology  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal axon guidance  (IAGP)
abnormal basisphenoid bone morphology  (IAGP)
abnormal blastocyst morphology  (IAGP)
abnormal brain commissure morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal carpal bone morphology  (IAGP)
abnormal cartilage development  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebellum vermis morphology  (IAGP)
abnormal cervical axis morphology  (IAGP)
abnormal chemokine level  (IAGP)
abnormal chorion morphology  (IAGP)
abnormal cochlea morphology  (IAGP)
abnormal cochlear hair cell development  (IAGP)
abnormal cochlear hair cell morphology  (IAGP)
abnormal cochlear nerve compound action potential  (IAGP)
abnormal cochlear sensory epithelium morphology  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal digestive system physiology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal dorsal telencephalic commissure morphology  (IAGP)
abnormal ear physiology  (IAGP)
abnormal ear position  (IEA)
abnormal ear shape  (IAGP)
abnormal egg cylinder morphology  (IAGP)
abnormal embryo development  (IAGP)
abnormal embryo size  (IEA)
abnormal embryonic autopod plate morphology  (IAGP)
abnormal embryonic epiblast morphology  (IAGP)
abnormal embryonic growth/weight/body size  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal embryonic-extraembryonic boundary morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum granulosum morphology  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal fetal cardiomyocyte proliferation  (IAGP)
abnormal forelimb bud morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal forelimb stylopod morphology  (IAGP)
abnormal forelimb zeugopod morphology  (IAGP)
abnormal frontal lobe morphology  (IAGP)
abnormal gait  (IAGP)
abnormal gastrulation  (IAGP)
abnormal gastrulation movements  (IAGP)
abnormal hair cycle  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal head fold morphology  (IAGP)
abnormal head mesenchyme morphology  (IAGP)
abnormal heart development  (IAGP)
abnormal heart tube morphology  (IAGP)
abnormal hindlimb morphology  (IAGP)
abnormal hippocampal commissure morphology  (IAGP)
abnormal hyoid bone lesser horn morphology  (IAGP)
abnormal incudostapedial joint morphology  (IAGP)
abnormal incus body morphology  (IAGP)
abnormal incus long process morphology  (IAGP)
abnormal incus morphology  (IAGP)
abnormal incus short process morphology  (IAGP)
abnormal inner ear morphology  (IAGP)
abnormal kidney development  (IAGP)
abnormal lateral plate mesoderm morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal limb morphology  (IAGP)
abnormal locus ceruleus morphology  (IAGP)
abnormal malleus morphology  (IAGP)
abnormal mast cell morphology  (IAGP)
abnormal maxillary-premaxillary suture morphology  (IAGP)
abnormal mesoderm development  (IAGP)
abnormal metanephric mesenchyme morphology  (IAGP)
abnormal midbrain morphology  (IAGP)
abnormal middle ear morphology  (IAGP)
abnormal middle ear ossicle morphology  (IAGP)
abnormal motor neuron morphology  (IAGP)
abnormal myocardial fiber morphology  (IAGP)
abnormal neural crest cell migration  (IAGP)
abnormal neural crest cell morphology  (IAGP)
abnormal neural fold formation  (IAGP)
abnormal neural fold morphology  (IAGP)
abnormal neural plate morphology  (IAGP)
abnormal neural tube closure  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal notochordal process morphology  (IAGP)
abnormal organ of Corti morphology  (IAGP)
abnormal orientation of inner hair cell stereociliary bundles  (IAGP)
abnormal outer ear morphology  (IAGP)
abnormal palatine bone morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal pinna reflex  (IAGP)
abnormal placenta size  (IEA)
abnormal posterior primitive streak morphology  (IAGP)
abnormal posture  (IAGP)
abnormal primitive endoderm morphology  (IAGP)
abnormal primitive streak morphology  (IAGP)
abnormal pterygoid bone morphology  (IAGP)
abnormal reproductive system physiology  (IAGP)
abnormal respiratory quotient  (IEA)
abnormal retrotympanic process morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal rostral-caudal axis patterning  (IAGP)
abnormal rostral-caudal body axis extension  (IAGP)
abnormal second pharyngeal arch morphology  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal skin adnexa morphology  (IAGP)
abnormal skin appearance  (IAGP)
abnormal small intestine crypts of Lieberkuhn morphology  (IAGP)
abnormal small intestine morphology  (IAGP)
abnormal snout morphology  (IAGP)
abnormal somite development  (IAGP)
abnormal somite size  (IAGP)
abnormal stapes morphology  (IAGP)
abnormal stapes posterior crus morphology  (IAGP)
abnormal sternocostal joint morphology  (IAGP)
abnormal styloid process morphology  (IAGP)
abnormal tail development  (IAGP)
abnormal tail morphology  (IAGP)
abnormal tarsal bone morphology  (IAGP)
abnormal temporal bone squamous part morphology  (IAGP)
abnormal thoracic cage morphology  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal tongue morphology  (IAGP)
abnormal trochlear nerve morphology  (IAGP)
abnormal ureteric bud elongation  (IAGP)
abnormal ureteric bud invasion  (IAGP)
abnormal ureteric bud morphology  (IAGP)
abnormal urethra urothelium morphology  (IAGP)
abnormal vascular development  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal visceral yolk sac endoderm morphology  (IAGP)
abnormal visceral yolk sac mesenchyme morphology  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
abnormal viscerocranium morphology  (IAGP)
absent cerebellum vermis  (IAGP)
absent cochlear outer hair cells  (IAGP)
absent gonial bone  (IAGP)
absent hair follicles  (IAGP)
absent incus lenticular process  (IAGP)
absent inferior colliculus  (IAGP)
absent kidney  (IAGP)
absent limb buds  (IAGP)
absent mast cells  (IAGP)
absent metanephric mesenchyme  (IAGP)
absent middle ear ossicles  (IAGP)
absent organ of Corti supporting cells  (IAGP)
absent round window  (IAGP)
absent sebaceous gland  (IAGP)
absent second pharyngeal arch  (IAGP)
absent somites  (IAGP)
absent stapes head  (IAGP)
absent tympanic ring  (IAGP)
absent visceral yolk sac blood islands  (IAGP)
acanthosis  (IAGP)
alopecia  (IAGP)
bleb  (IAGP)
broad limb buds  (IAGP)
caudal body truncation  (IAGP)
cervical vertebral transformation  (IAGP)
cleft palate  (IAGP)
craniofacial asymmetry  (IAGP)
craniorachischisis  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased caudal vertebrae number  (IAGP)
decreased cochlear hair cell number  (IAGP)
decreased cochlear outer hair cell number  (IAGP)
decreased embryo size  (IAGP)
decreased endocochlear potential  (IAGP)
decreased inferior colliculus size  (IAGP)
decreased kidney cell proliferation  (IAGP)
decreased lumbar vertebrae number  (IAGP)
decreased paraxial mesoderm size  (IAGP)
decreased renal glomerulus number  (IAGP)
decreased somite size  (IAGP)
decreased thoracic vertebrae number  (IAGP)
decreased tympanic ring size  (IAGP)
dermatitis  (IAGP)
dilated heart left ventricle  (IAGP)
dilated heart right ventricle  (IAGP)
dry skin  (IAGP)
ectopic ureteric bud  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between implantation and somite formation, complete penetrance  (IAGP)
embryonic lethality between implantation and somite formation, incomplete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, incomplete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
embryonic lethality prior to tooth bud stage  (IEA)
embryonic lethality, complete penetrance  (IAGP)
enlarged allantois  (IAGP)
enlarged heart  (IAGP)
enlarged heart atrium  (IAGP)
excessive cerumen  (IAGP)
excessive folding of visceral yolk sac  (IAGP)
facial asymmetry  (IAGP)
facial cleft  (IAGP)
failure of heart looping  (IAGP)
failure of palatal shelf elevation  (IAGP)
failure of primitive streak formation  (IAGP)
failure of somite differentiation  (IAGP)
female infertility  (IAGP)
fusion of atlas and occipital bones  (IAGP)
genital tubercle hypoplasia  (IAGP)
heart hypoplasia  (IAGP)
hydronephrosis  (IAGP)
impaired branching involved in ureteric bud morphogenesis  (IAGP)
impaired coordination  (IAGP)
impaired skin barrier function  (IAGP)
increased axial mesoderm size  (IAGP)
increased cochlear inner hair cell number  (IAGP)
increased IgE level  (IAGP)
increased IgG1 level  (IAGP)
increased IgG2a level  (IAGP)
increased keratinocyte proliferation  (IAGP)
increased kidney apoptosis  (IAGP)
increased mast cell number  (IAGP)
increased metanephric mesenchyme apoptosis  (IAGP)
increased or absent threshold for auditory brainstem response  (IEA)
increased osteoblast cell number  (IAGP)
increased osteoblast proliferation  (IAGP)
increased rib number  (IAGP)
increased susceptibility to otitis media  (IAGP)
increased thoracic vertebrae number  (IAGP)
incus hypoplasia  (IAGP)
kinked neural tube  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
long incisors  (IAGP)
lowered ear position  (IAGP)
lumbar vertebral transformation  (IAGP)
malleus hypoplasia  (IAGP)
middle ear ossicle hypoplasia  (IAGP)
midface hypoplasia  (IAGP)
midline facial cleft  (IAGP)
neonatal lethality  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
ocular hypertelorism  (IAGP)
oligodactyly  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
polydipsia  (IAGP)
postaxial polydactyly  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature coronal suture closure  (IAGP)
premature cranial suture closure  (IAGP)
premature maxillary-premaxillary suture closure  (IAGP)
premature metopic suture closure  (IAGP)
premature sagittal suture closure  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
progressive hair loss  (IAGP)
reduced male fertility  (IAGP)
rib bifurcation  (IAGP)
rib fusion  (IAGP)
sacral vertebral transformation  (IAGP)
second pharyngeal arch hypoplasia  (IAGP)
short mandible  (IAGP)
short nasal bone  (IAGP)
short snout  (IAGP)
short tail  (IAGP)
short tibia  (IAGP)
skin fibrosis  (IAGP)
skin inflammation  (IAGP)
small cranium  (IAGP)
small ears  (IAGP)
small gonial bone  (IAGP)
small hair follicles  (IAGP)
small kidney  (IAGP)
small proamniotic cavity  (IAGP)
small round window  (IAGP)
small second pharyngeal arch  (IAGP)
small ureteric bud  (IAGP)
small visceral yolk sac  (IAGP)
spina bifida  (IAGP)
stapes hypoplasia  (IAGP)
styloid process hypoplasia  (IAGP)
supernumerary teeth  (IAGP)
syndactyly  (IAGP)
thick epidermis  (IAGP)
thin myocardium  (IAGP)
thin ventricular wall  (IAGP)
thoracic vertebral transformation  (IAGP)
tympanic ring hypoplasia  (IAGP)
vertebral transformation  (IAGP)
References

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Additional References at PubMed
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Genomics

Comparative Map Data
Fgfr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,008,775 - 26,065,734 (+)NCBIGRCm39mm39
GRCm38825,518,759 - 25,575,718 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,513,654 - 25,575,718 (+)EnsemblGRCm38mm10GRCm38
MGSCv37826,629,244 - 26,686,186 (+)NCBIGRCm37mm9NCBIm37
MGSCv36826,997,826 - 27,039,466 (+)NCBImm8
Celera826,986,822 - 27,044,074 (+)NCBICelera
Cytogenetic Map8A2NCBI
cM Map814.12NCBI
FGFR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl838,400,215 - 38,468,834 (-)EnsemblGRCh38hg38GRCh38
GRCh38838,411,143 - 38,468,635 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37838,268,656 - 38,326,352 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,387,813 - 38,445,509 (-)NCBINCBI36hg18NCBI36
Build 34838,389,448 - 38,445,293NCBI
Celera837,221,633 - 37,279,334 (-)NCBI
Cytogenetic Map8p11.23NCBI
HuRef836,802,638 - 36,860,684 (-)NCBIHuRef
CHM1_1838,470,562 - 38,528,261 (-)NCBICHM1_1
Fgfr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01671,265,390 - 71,319,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,266,248 - 71,319,449 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,924,716 - 70,977,998 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,869,974 - 70,910,045 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11670,870,238 - 70,910,310 (-)NCBI
Celera1664,402,647 - 64,442,189 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
Fgfr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546314,013,247 - 14,064,111 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546314,013,247 - 14,064,354 (-)NCBIChiLan1.0ChiLan1.0
FGFR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1834,890,147 - 34,948,904 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl834,890,147 - 34,948,904 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0837,713,133 - 37,773,098 (-)NCBIMhudiblu_PPA_v0panPan3
FGFR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1627,031,588 - 27,078,261 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11627,029,902 - 27,080,514 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fgfr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367101,760,365 - 1,815,269 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGFR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1548,053,340 - 48,106,746 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11548,053,895 - 48,106,634 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,216,111 - 55,269,152 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGFR1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl836,427,110 - 36,485,508 (-)Ensembl
ChlSab1.1836,426,116 - 36,485,683 (-)NCBI
Fgfr1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247805,161,245 - 5,212,641 (+)NCBI

Position Markers
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,572,763 - 25,573,613UniSTSGRCm38
MGSCv37826,684,082 - 26,684,317UniSTSGRCm37
Celera827,041,122 - 27,041,972UniSTS
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
cM Map810.0UniSTS
cM Map810.0UniSTS
cM Map810.0UniSTS
cM Map810.0UniSTS
AW208770  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,574,313 - 25,574,422UniSTSGRCm38
MGSCv37826,684,785 - 26,684,894UniSTSGRCm37
Celera827,042,672 - 27,042,781UniSTS
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
Whitehead/MRC_RH8290.46UniSTS
PMC154461P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,565,927 - 25,566,710UniSTSGRCm38
MGSCv37826,676,399 - 26,677,182UniSTSGRCm37
Celera827,034,152 - 27,034,935UniSTS
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
PMC195961P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,565,927 - 25,566,070UniSTSGRCm38
MGSCv37826,676,399 - 26,676,542UniSTSGRCm37
Celera827,034,152 - 27,034,295UniSTS
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
MARC_14569-14570:1009480763:3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,573,145 - 25,573,792UniSTSGRCm38
MGSCv37826,683,617 - 26,684,264UniSTSGRCm37
Celera827,041,504 - 27,042,151UniSTS
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38825,573,610 - 25,573,845UniSTSGRCm38
MGSCv37826,684,082 - 26,684,317UniSTSGRCm37
Celera827,041,969 - 27,042,204UniSTS
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
cM Map810.0UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS
Fgfr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8A2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11533914Mts5_mmammary tumor susceptibility 5 (mouse)8130397432Mouse
4140978Nilac5_mnicotine induced locomotor activity 5 (mouse)Not determined8131723288Mouse
27226756Femd2_mfemur midshaft diameter 2, 5 week (mouse)8490000034600000Mouse
1301532Scc8_mcolon tumor susceptibility 8 (mouse)Not determined8716249934642953Mouse
1300906Ap8q_malcohol preference 8 QTL (mouse)Not determined8749417341494326Mouse
1301128Sluc20_msusceptibility to lung cancer 20 (mouse)Not determined8761318541613356Mouse
1301929Eae24_msusceptibility to experimental allergic encephalomyelitis 24 (mouse)Not determined8761318541613356Mouse
10412209Cypr7_mcytokine production 7 (mouse)Not determined8761318541613356Mouse
11532713Sluc42_msusceptibility to lung cancer 42 (mouse)81339721034854071Mouse
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1301088Alcw6_malcohol withdrawal 6 (mouse)Not determined81501654449016701Mouse
1300912Daq19_mdirectional asymmetry QTL 19 (mouse)Not determined81501654449016701Mouse
1301298Pgia4_mproteoglycan induced arthritis 4 (mouse)Not determined81607934550079669Mouse
4142199Poats1_mpost-ovarectomy adrenal tumor susceptibility 1 (mouse)Not determined1703261028359439Mouse
1301550Fembrs2_mfemur breaking strength 2 (mouse)Not determined81785394351854071Mouse
1301160Eae14_msusceptibility to experimental allergic encephalomyelitis 14 (mouse)Not determined81898786452987996Mouse
1300603Cd8ts2_mCD8 T cell subset 2 (mouse)Not determined81898786452987996Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir133bmmu-miR-133b-5pOncomiRDBexternal_infoNANA23296701

Predicted Target Of
Summary Value
Count of predictions:5845
Count of miRNA genes:839
Interacting mature miRNAs:1130
Transcripts:ENSMUST00000084027, ENSMUST00000117179, ENSMUST00000119398, ENSMUST00000120106, ENSMUST00000124228, ENSMUST00000126118, ENSMUST00000133936, ENSMUST00000138104, ENSMUST00000138455, ENSMUST00000145218, ENSMUST00000148322, ENSMUST00000155564, ENSMUST00000167764, ENSMUST00000178276, ENSMUST00000179592
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001079908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001079909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC160526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02172397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF154570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF176552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI480534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK028354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU611199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB524826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF532036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M33760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M65053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S47233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S74765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U22324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U23445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X51893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000084027   ⟹   ENSMUSP00000081041
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,518,759 - 25,575,718 (+)Ensembl
RefSeq Acc Id: ENSMUST00000117179   ⟹   ENSMUSP00000113909
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,518,795 - 25,574,781 (+)Ensembl
RefSeq Acc Id: ENSMUST00000119398   ⟹   ENSMUSP00000113855
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,518,789 - 25,574,779 (+)Ensembl
RefSeq Acc Id: ENSMUST00000120106
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,566,850 - 25,574,784 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124228   ⟹   ENSMUSP00000116564
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,519,837 - 25,555,729 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126118
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,563,405 - 25,574,785 (+)Ensembl
RefSeq Acc Id: ENSMUST00000133936
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,569,723 - 25,572,457 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138104   ⟹   ENSMUSP00000148135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,555,617 - 25,572,441 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138455   ⟹   ENSMUSP00000147898
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,558,074 - 25,563,714 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145218
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,569,486 - 25,572,395 (+)Ensembl
RefSeq Acc Id: ENSMUST00000148322
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,518,895 - 25,555,658 (+)Ensembl
RefSeq Acc Id: ENSMUST00000155564   ⟹   ENSMUSP00000117884
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,513,654 - 25,555,568 (+)Ensembl
RefSeq Acc Id: ENSMUST00000167764   ⟹   ENSMUSP00000131343
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,532,281 - 25,574,577 (+)Ensembl
RefSeq Acc Id: ENSMUST00000178276   ⟹   ENSMUSP00000137515
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,518,772 - 25,575,714 (+)Ensembl
RefSeq Acc Id: ENSMUST00000179592   ⟹   ENSMUSP00000136640
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,518,772 - 25,575,714 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210504
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,566,000 - 25,569,323 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210778
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,519,344 - 25,558,227 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210846   ⟹   ENSMUSP00000148032
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,532,125 - 25,555,676 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211419
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl825,566,866 - 25,568,297 (+)Ensembl
RefSeq Acc Id: NM_001079908   ⟹   NP_001073377
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39826,008,775 - 26,065,734 (+)NCBI
GRCm38825,518,759 - 25,575,718 (+)NCBI
MGSCv37826,629,244 - 26,686,186 (+)RGD
Celera826,986,809 - 27,044,078 (+)NCBI
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001079909   ⟹   NP_001073378
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39826,008,775 - 26,065,734 (+)NCBI
GRCm38825,518,759 - 25,575,718 (+)NCBI
MGSCv37826,629,244 - 26,686,186 (+)RGD
Celera826,986,809 - 27,044,078 (+)NCBI
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_010206   ⟹   NP_034336
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39826,008,775 - 26,065,734 (+)NCBI
GRCm38825,518,759 - 25,575,718 (+)NCBI
MGSCv37826,629,244 - 26,686,186 (+)RGD
Celera826,986,809 - 27,044,078 (+)NCBI
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034336   ⟸   NM_010206
- Peptide Label: isoform 1 precursor
- UniProtKB: P16092 (UniProtKB/Swiss-Prot),   Q8CBY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001073377   ⟸   NM_001079908
- Peptide Label: isoform 2 precursor
- UniProtKB: P16092 (UniProtKB/Swiss-Prot),   Q8CBY7 (UniProtKB/TrEMBL),   Q8CIM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001073378   ⟸   NM_001079909
- Peptide Label: isoform 3 precursor
- UniProtKB: P16092 (UniProtKB/Swiss-Prot),   Q8CBY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000137515   ⟸   ENSMUST00000178276
RefSeq Acc Id: ENSMUSP00000113855   ⟸   ENSMUST00000119398
RefSeq Acc Id: ENSMUSP00000147898   ⟸   ENSMUST00000138455
RefSeq Acc Id: ENSMUSP00000116564   ⟸   ENSMUST00000124228
RefSeq Acc Id: ENSMUSP00000148135   ⟸   ENSMUST00000138104
RefSeq Acc Id: ENSMUSP00000148032   ⟸   ENSMUST00000210846
RefSeq Acc Id: ENSMUSP00000136640   ⟸   ENSMUST00000179592
RefSeq Acc Id: ENSMUSP00000131343   ⟸   ENSMUST00000167764
RefSeq Acc Id: ENSMUSP00000081041   ⟸   ENSMUST00000084027
RefSeq Acc Id: ENSMUSP00000113909   ⟸   ENSMUST00000117179
RefSeq Acc Id: ENSMUSP00000117884   ⟸   ENSMUST00000155564
Protein Domains
Ig-like   Ig-like C2-type   Protein kinase

Promoters
RGD ID:8666755
Promoter ID:EPDNEW_M11409
Type:initiation region
Name:Fgfr1_1
Description:Mus musculus fibroblast growth factor receptor 1 , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38825,518,792 - 25,518,852EPDNEW
RGD ID:6843156
Promoter ID:MM_KWN:54004
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:OTTMUST00000076877
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,623,696 - 26,624,196 (+)MPROMDB
RGD ID:6843150
Promoter ID:MM_KWN:54005
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000084027,   ENSMUST00000117179,   ENSMUST00000118241,   ENSMUST00000119398,   ENSMUST00000120612,   NM_001079908,   NM_001079909,   NM_010206,   OTTMUST00000076878,   OTTMUST00000076879
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,629,084 - 26,629,584 (+)MPROMDB
RGD ID:6843157
Promoter ID:MM_KWN:54006
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Lung
Transcripts:ENSMUST00000120106,   OTTMUST00000076871,   UC009LGB.1,   UC009LGC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,642,011 - 26,643,142 (+)MPROMDB
RGD ID:6843158
Promoter ID:MM_KWN:54008
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day4,   Brain,   Kidney,   Lung
Transcripts:OTTMUST00000076872,   UC009LGE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,665,186 - 26,666,022 (+)MPROMDB
RGD ID:6843151
Promoter ID:MM_KWN:54010
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Brain
Transcripts:OTTMUST00000076873
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,667,546 - 26,669,007 (+)MPROMDB
RGD ID:6843152
Promoter ID:MM_KWN:54011
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4
Transcripts:OTTMUST00000076876
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,673,686 - 26,674,907 (+)MPROMDB
RGD ID:6843153
Promoter ID:MM_KWN:54012
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3
Transcripts:OTTMUST00000076874,   OTTMUST00000076875
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36826,679,959 - 26,680,459 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95522 AgrOrtholog
Ensembl Genes ENSMUSG00000031565 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000081041 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000113855 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000113909 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000116564 UniProtKB/TrEMBL
  ENSMUSP00000117884 UniProtKB/TrEMBL
  ENSMUSP00000131343 UniProtKB/Swiss-Prot
  ENSMUSP00000136640 UniProtKB/TrEMBL
  ENSMUSP00000137515 UniProtKB/Swiss-Prot
  ENSMUSP00000147898 UniProtKB/TrEMBL
  ENSMUSP00000148032 UniProtKB/TrEMBL
  ENSMUSP00000148135 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000084027 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000117179 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000119398 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000124228 UniProtKB/TrEMBL
  ENSMUST00000138104 UniProtKB/TrEMBL
  ENSMUST00000138455 UniProtKB/TrEMBL
  ENSMUST00000155564 UniProtKB/TrEMBL
  ENSMUST00000167764 UniProtKB/Swiss-Prot
  ENSMUST00000178276 UniProtKB/Swiss-Prot
  ENSMUST00000179592 UniProtKB/TrEMBL
  ENSMUST00000210846 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FGF_rcpt_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGF_rcpt_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FGFR_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14182 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95522 ENTREZGENE
NCBI Gene 14182 ENTREZGENE
Pfam FGFR3_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fgfr1 PhenoGen
PIRSF FGFR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.265716 ENTREZGENE
UniProt A0A1B0GSD9_MOUSE UniProtKB/TrEMBL
  A0A1B0GSQ7_MOUSE UniProtKB/TrEMBL
  A0A1B0GSZ6_MOUSE UniProtKB/TrEMBL
  D3YW77_MOUSE UniProtKB/TrEMBL
  D3Z4V6_MOUSE UniProtKB/TrEMBL
  FGFR1_MOUSE UniProtKB/Swiss-Prot
  J3QN85_MOUSE UniProtKB/TrEMBL
  P16092 ENTREZGENE
  Q3TJ05_MOUSE UniProtKB/TrEMBL
  Q60818_MOUSE UniProtKB/TrEMBL
  Q61565_MOUSE UniProtKB/TrEMBL
  Q8CBY7 ENTREZGENE, UniProtKB/TrEMBL
  Q8CIM9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary E9Q2P4 UniProtKB/Swiss-Prot
  Q01736 UniProtKB/Swiss-Prot
  Q60830 UniProtKB/Swiss-Prot
  Q61562 UniProtKB/Swiss-Prot
  Q80T10 UniProtKB/Swiss-Prot
  Q8CFK8 UniProtKB/Swiss-Prot
  Q9QZM7 UniProtKB/Swiss-Prot