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Gene: Pln (phospholamban) Mus musculus
Symbol: Pln
Name: phospholamban
Description: ENCODES a protein that exhibits protein homodimerization activity; ATPase inhibitor activity (ortholog); INVOLVED IN adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process; cardiac muscle tissue development; cellular calcium ion homeostasis; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abnormal calcium ion homeostasis; abnormal cardiac muscle contractility; abnormal cardiac muscle relaxation; ASSOCIATED WITH atrial fibrillation (ortholog); autistic disorder (ortholog); cardiac arrest (ortholog); FOUND IN endoplasmic reticulum membrane; sarcoplasmic reticulum; sarcoplasmic reticulum membrane; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 3,4-methylenedioxymethamphetamine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cardiac phospholamban; Plb
Homo sapiens (human) : PLN (phospholamban)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pln (phospholamban)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pln (phospholamban)
Pan paniscus (bonobo/pygmy chimpanzee) : PLN (phospholamban)
Canis lupus familiaris (dog) : PLN (phospholamban)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pln (phospholamban)
Sus scrofa (pig) : PLN (phospholamban)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381053,337,686 - 53,345,999 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371053,057,492 - 53,065,805 (+)NCBIGRCm37mm9NCBIm37
MGSCv361053,026,122 - 53,034,396 (+)NCBImm8
Celera1054,164,488 - 54,172,801 (+)NCBICelera
Cytogenetic Map10 B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pln
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732405
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.