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Gene: Tnfaip1 (tumor necrosis factor, alpha-induced protein 1 (endothelial)) Mus musculus
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Symbol: Tnfaip1
Name: tumor necrosis factor, alpha-induced protein 1 (endothelial)
Description: Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of Rho protein signal transduction; and stress fiber assembly. Predicted to localize to the Cul3-RING ubiquitin ligase complex and endosome. Is expressed in brain; heart valve; sensory organ; and skeleton. Orthologous to human TNFAIP1 (TNF alpha induced protein 1); INTERACTS WITH 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bacurd2; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; Edp-1; Edp1; Tnfip1; tumor necrosis factor induced protein 1; tumor necrosis factor, alpha-induced protein 1, endothelial
Orthologs:
Homo sapiens (human) : TNFAIP1 (TNF alpha induced protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfaip1 (TNF alpha induced protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfaip1 (TNF alpha induced protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFAIP1 (TNF alpha induced protein 1)
Canis lupus familiaris (dog) : TNFAIP1 (TNF alpha induced protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfaip1 (TNF alpha induced protein 1)
Sus scrofa (pig) : TNFAIP1 (TNF alpha induced protein 1)
Chlorocebus sabaeus (African green monkey) : TNFAIP1 (TNF alpha induced protein 1)
Heterocephalus glaber (naked mole-rat) : Tnfaip1 (TNF alpha induced protein 1)
more info ...
Related Pseudogenes: Gm14589   Gm14677   Gm14678   Gm19151  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1178,522,850 - 78,536,332 (-)EnsemblGRCm38mm10GRCm38
GRCm381178,522,850 - 78,536,270 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,336,352 - 78,349,762 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,339,043 - 78,352,389 (-)NCBImm8
Celera1188,154,923 - 88,168,333 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tnfaip1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550978
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.