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Gene: Tnfaip1 (tumor necrosis factor, alpha-induced protein 1 (endothelial)) Mus musculus
Symbol: Tnfaip1
Name: tumor necrosis factor, alpha-induced protein 1 (endothelial)
Description: Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of Rho protein signal transduction; and stress fiber assembly. Predicted to localize to the Cul3-RING ubiquitin ligase complex and endosome. Is expressed in brain; heart valve; sensory organ; and skeleton. Orthologous to human TNFAIP1 (TNF alpha induced protein 1); INTERACTS WITH 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bacurd2; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; Edp-1; Edp1; Tnfip1; tumor necrosis factor induced protein 1; tumor necrosis factor, alpha-induced protein 1, endothelial
Homo sapiens (human) : TNFAIP1 (TNF alpha induced protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfaip1 (TNF alpha induced protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfaip1 (TNF alpha induced protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFAIP1 (TNF alpha induced protein 1)
Canis lupus familiaris (dog) : TNFAIP1 (TNF alpha induced protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfaip1 (TNF alpha induced protein 1)
Sus scrofa (pig) : TNFAIP1 (TNF alpha induced protein 1)
Chlorocebus sabaeus (African green monkey) : TNFAIP1 (TNF alpha induced protein 1)
Heterocephalus glaber (naked mole-rat) : Tnfaip1 (TNF alpha induced protein 1)
more info ...
Related Pseudogenes: Gm14589   Gm14677   Gm14678   Gm19151  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1178,522,850 - 78,536,332 (-)EnsemblGRCm38mm10GRCm38
GRCm381178,522,850 - 78,536,270 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371178,336,352 - 78,349,762 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,339,043 - 78,352,389 (-)NCBImm8
Celera1188,154,923 - 88,168,333 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnfaip1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550978
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.