Akap6 (A kinase anchor protein 6) - Rat Genome Database

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Gene: Akap6 (A kinase anchor protein 6) Mus musculus
Analyze
Symbol: Akap6
Name: A kinase anchor protein 6 (Ensembl:A kinase (PRKA) anchor protein 6)
RGD ID: 1550845
MGI Page MGI
Description: Predicted to enable several functions, including enzyme binding activity; protein kinase A regulatory subunit binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including positive regulation of cation transmembrane transport; positive regulation of protein metabolic process; and regulation of muscle system process. Located in nuclear membrane and perinuclear region of cytoplasm. Is expressed in gut; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in anorexia nervosa and ovary epithelial cancer. Orthologous to human AKAP6 (A-kinase anchoring protein 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A kinase (PRKA) anchor protein 6; A-kinase anchor protein 6; A-kinase anchoring protein alpha; A-kinase anchoring protein beta; AI482140; Akapalpha; Akapbeta; anchor protein 6; MGC73457; PRKA
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391252,745,371 - 53,202,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1252,746,166 - 53,202,382 (+)EnsemblGRCm39 Ensembl
GRCm381252,698,588 - 53,155,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1252,699,383 - 53,155,599 (+)EnsemblGRCm38mm10GRCm38
MGSCv371253,800,370 - 54,252,002 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361253,620,875 - 54,072,638 (+)NCBIMGSCv36mm8
Celera1254,009,109 - 54,451,716 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A-kinase anchoring proteins: from protein complexes to physiology and disease. Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406.
2. mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. Dodge KL, etal., EMBO J 2001 Apr 17;20(8):1921-30.
3. Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. Earp M, etal., PLoS One. 2018 Jul 6;13(7):e0197561. doi: 10.1371/journal.pone.0197561. eCollection 2018.
4. The scaffold protein muscle A-kinase anchoring protein beta orchestrates cardiac myocyte hypertrophic signaling required for the development of heart failure. Kritzer MD, etal., Circ Heart Fail. 2014 Jul;7(4):663-72. doi: 10.1161/CIRCHEARTFAILURE.114.001266. Epub 2014 May 8.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Decreased mAKAP, ryanodine receptor, and SERCA2a gene expression in mdx hearts. Rohman MS, etal., Biochem Biophys Res Commun. 2003 Oct 10;310(1):228-35.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11. Localized effects of cAMP mediated by distinct routes of protein kinase A. Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.
12. A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa. Wang K, etal., Mol Psychiatry. 2011 Sep;16(9):949-59. doi: 10.1038/mp.2010.107. Epub 2010 Nov 16.
13. Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia. Wilhelm T, etal., Epigenetics. 2016;11(2):110-9. doi: 10.1080/15592294.2016.1145327. Epub 2016 Feb 18.
14. Temporal profile of Src, SSeCKS, and angiogenic factors after focal cerebral ischemia: correlations with angiogenesis and cerebral edema. Zan L, etal., Neurochem Int. 2011 Jul;58(8):872-9. doi: 10.1016/j.neuint.2011.02.014. Epub 2011 Feb 18.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11544199   PMID:11590243   PMID:12466851   PMID:14621295   PMID:16141072   PMID:16141073   PMID:16337591  
PMID:16602821   PMID:18799693   PMID:19574217   PMID:20164376   PMID:21267068   PMID:21873635   PMID:23261540   PMID:23540699   PMID:24427155   PMID:26563778   PMID:26844267   PMID:26930384  
PMID:26980469   PMID:31325238   PMID:34321999  


Genomics

Comparative Map Data
Akap6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391252,745,371 - 53,202,351 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1252,746,166 - 53,202,382 (+)EnsemblGRCm39 Ensembl
GRCm381252,698,588 - 53,155,568 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1252,699,383 - 53,155,599 (+)EnsemblGRCm38mm10GRCm38
MGSCv371253,800,370 - 54,252,002 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361253,620,875 - 54,072,638 (+)NCBIMGSCv36mm8
Celera1254,009,109 - 54,451,716 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.18NCBI
AKAP6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381432,329,298 - 32,837,684 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1432,329,298 - 32,837,684 (+)EnsemblGRCh38hg38GRCh38
GRCh371432,798,504 - 33,306,890 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361431,868,274 - 32,372,018 (+)NCBINCBI36Build 36hg18NCBI36
Build 341431,868,273 - 32,372,018NCBI
Celera1412,665,076 - 13,167,767 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1412,916,606 - 13,419,742 (+)NCBIHuRef
CHM1_11432,798,120 - 33,300,973 (+)NCBICHM1_1
T2T-CHM13v2.01426,401,181 - 27,034,449 (+)NCBIT2T-CHM13v2.0
Akap6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8675,919,350 - 76,359,667 (+)NCBIGRCr8
mRatBN7.2670,184,101 - 70,624,369 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl670,184,175 - 70,619,738 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx670,602,131 - 71,041,292 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0670,908,778 - 71,347,917 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0670,348,346 - 70,787,478 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0673,553,111 - 73,991,992 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl673,553,210 - 73,990,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0683,111,409 - 83,547,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4673,010,779 - 73,354,520 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1673,016,484 - 73,357,646 (+)NCBI
Celera669,046,483 - 69,480,156 (+)NCBICelera
Cytogenetic Map6q23NCBI
Akap6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540928,077,621 - 28,516,944 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540928,067,814 - 28,516,881 (-)NCBIChiLan1.0ChiLan1.0
AKAP6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21533,530,973 - 34,155,583 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11432,747,476 - 33,372,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01412,978,221 - 13,602,732 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11431,290,939 - 31,792,166 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1431,395,026 - 31,792,166 (+)Ensemblpanpan1.1panPan2
AKAP6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1811,403,655 - 11,882,684 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl811,406,280 - 11,874,406 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha811,299,751 - 11,679,685 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0811,415,673 - 11,984,846 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl811,508,505 - 11,986,716 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1811,188,259 - 11,668,695 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0811,269,184 - 11,750,344 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0811,547,419 - 12,028,362 (+)NCBIUU_Cfam_GSD_1.0
Akap6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864043,239,054 - 43,722,811 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364946,744,892 - 7,228,686 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364946,744,923 - 7,228,670 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl766,915,881 - 67,375,177 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1766,913,541 - 67,462,147 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2771,765,469 - 72,075,989 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Akap6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248383,999,663 - 4,393,055 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248383,992,769 - 4,393,055 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Akap6
15718 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1009
Count of miRNA genes:550
Interacting mature miRNAs:683
Transcripts:ENSMUST00000095737
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
13524839Ppiq10_mprepulse inhibition QTL 10 (mouse)121304319554945798Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
12904956Edlmmq10_mextensor digitorum longus muscle mass QTL 10 (mouse)121973983353739833Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
10402492Dipa8_mdrug induced psychomotor activation 8 (mouse)Not determined123493387268934019Mouse
1300818Bbaa10_mB.burgdorferi-associated arthritis 10 (mouse)Not determined123509100465511019Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
1357479Splwt1_mspleen weight 1 (mouse)Not determined124169317590887526Mouse
1357757Lnopy2_mlens opacity 2 (mouse)Not determined125284662686846796Mouse
1357749Vtbt13_mvertebral trabecular bone trait 13 (mouse)Not determined125313200287132145Mouse
12904004Opfaq11_mopen field activity QTL 11 (mouse)125315562457276756Mouse

Markers in Region
AI482140  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381253,150,791 - 53,150,870UniSTSGRCm38
MGSCv371254,251,778 - 54,251,857UniSTSGRCm37
Celera1254,451,492 - 54,451,571UniSTS
Cytogenetic Map12C1UniSTS
Whitehead/MRC_RH12533.63UniSTS
D12Mit126  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381253,028,586 - 53,028,721UniSTSGRCm38
MGSCv371254,129,573 - 54,129,708UniSTSGRCm37
Celera1254,329,296 - 54,329,433UniSTS
Cytogenetic Map12C1UniSTS
cM Map1222.0UniSTS
Whitehead Genetic1217.5UniSTS
Whitehead_YAC12 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006515829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017315055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030246700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036157394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC155233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC155808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC161047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK129115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT030137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ233645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ233646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000095737   ⟹   ENSMUSP00000093406
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1252,746,166 - 53,202,382 (+)Ensembl
GRCm38.p6 Ensembl1252,699,383 - 53,155,599 (+)Ensembl
RefSeq Acc Id: ENSMUST00000219786   ⟹   ENSMUSP00000151871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1252,842,619 - 53,195,546 (+)Ensembl
GRCm38.p6 Ensembl1252,795,836 - 53,148,763 (+)Ensembl
RefSeq Acc Id: NM_198111   ⟹   NP_932779
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,746,166 - 53,197,798 (+)NCBI
GRCm381252,699,383 - 53,151,015 (+)NCBI
MGSCv371253,800,370 - 54,252,002 (+)RGD
Celera1254,009,109 - 54,451,716 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006515821   ⟹   XP_006515884
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,745,371 - 53,202,351 (+)NCBI
GRCm381252,698,588 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515822   ⟹   XP_006515885
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,745,655 - 53,202,351 (+)NCBI
GRCm381252,698,872 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515824   ⟹   XP_006515887
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,837,761 - 53,202,351 (+)NCBI
GRCm381252,790,968 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515825   ⟹   XP_006515888
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,837,477 - 53,202,351 (+)NCBI
GRCm381252,790,679 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515826   ⟹   XP_006515889
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,819,695 - 53,202,351 (+)NCBI
GRCm381252,772,898 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515827   ⟹   XP_006515890
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,837,477 - 53,202,351 (+)NCBI
GRCm381252,790,679 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515828   ⟹   XP_006515891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,745,371 - 53,202,351 (+)NCBI
GRCm381252,698,588 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006515829   ⟹   XP_006515892
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,900,617 - 53,202,351 (+)NCBI
GRCm381252,852,879 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017315055   ⟹   XP_017170544
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,745,975 - 53,202,351 (+)NCBI
GRCm381252,699,192 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030246699   ⟹   XP_030102559
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,819,695 - 53,202,351 (+)NCBI
GRCm381252,772,899 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030246700   ⟹   XP_030102560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,900,617 - 53,202,351 (+)NCBI
GRCm381252,852,879 - 53,155,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157393   ⟹   XP_036013286
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,901,443 - 53,202,351 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157394   ⟹   XP_036013287
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391252,901,436 - 53,202,351 (+)NCBI
Sequence:
RefSeq Acc Id: NP_932779   ⟸   NM_198111
- UniProtKB: E9Q9K8 (UniProtKB/TrEMBL),   Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515885   ⟸   XM_006515822
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515884   ⟸   XM_006515821
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515891   ⟸   XM_006515828
- Peptide Label: isoform X2
- UniProtKB: E9Q9K8 (UniProtKB/TrEMBL),   Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515889   ⟸   XM_006515826
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515890   ⟸   XM_006515827
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515888   ⟸   XM_006515825
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515887   ⟸   XM_006515824
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006515892   ⟸   XM_006515829
- Peptide Label: isoform X3
- UniProtKB: Q2VEB3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017170544   ⟸   XM_017315055
- Peptide Label: isoform X1
- UniProtKB: Q3UHI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030102559   ⟸   XM_030246699
- Peptide Label: isoform X2
- UniProtKB: E9Q9K8 (UniProtKB/TrEMBL),   Q3UHI8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030102560   ⟸   XM_030246700
- Peptide Label: isoform X3
- UniProtKB: Q2VEB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000151871   ⟸   ENSMUST00000219786
RefSeq Acc Id: ENSMUSP00000093406   ⟸   ENSMUST00000095737
RefSeq Acc Id: XP_036013287   ⟸   XM_036157394
- Peptide Label: isoform X4
- UniProtKB: Q2VEB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036013286   ⟸   XM_036157393
- Peptide Label: isoform X4
- UniProtKB: Q2VEB3 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9Q9K8-F1-model_v2 AlphaFold E9Q9K8 1-2307 view protein structure

Promoters
RGD ID:8678262
Promoter ID:EPDNEW_M17162
Type:initiation region
Name:Akap6_1
Description:Mus musculus A kinase anchor protein 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17163  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381252,699,344 - 52,699,404EPDNEW
RGD ID:8678264
Promoter ID:EPDNEW_M17163
Type:single initiation site
Name:Akap6_2
Description:Mus musculus A kinase anchor protein 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M17162  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381252,739,474 - 52,739,534EPDNEW
RGD ID:6822710
Promoter ID:MM_KWN:11631
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ENSMUST00000065911,   ENSMUST00000110722,   NM_198111
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361253,800,121 - 53,800,621 (+)MPROMDB
RGD ID:6822711
Promoter ID:MM_KWN:11632
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:UC007NNN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361253,954,926 - 53,955,426 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3050566 AgrOrtholog
Ensembl Genes ENSMUSG00000061603 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000095737 ENTREZGENE
  ENSMUST00000095737.5 UniProtKB/TrEMBL
  ENSMUST00000219786.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.60 UniProtKB/TrEMBL
InterPro Spectrin/alpha-actinin UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/TrEMBL
KEGG Report mmu:238161 UniProtKB/TrEMBL
MGD MGI:3050566 ENTREZGENE
NCBI Gene 238161 ENTREZGENE
PANTHER A-KINASE ANCHOR PROTEIN 6 UniProtKB/TrEMBL
  PKA ANCHORING PROTEIN UniProtKB/TrEMBL
Pfam Spectrin UniProtKB/TrEMBL
PhenoGen Akap6 PhenoGen
SMART SPEC UniProtKB/TrEMBL
Superfamily-SCOP Spectrin repeat UniProtKB/TrEMBL
UniProt E9Q9K8 ENTREZGENE, UniProtKB/TrEMBL
  Q2VEB3 ENTREZGENE, UniProtKB/TrEMBL
  Q2VEB4_MOUSE UniProtKB/TrEMBL
  Q3TRB0_MOUSE UniProtKB/TrEMBL
  Q3UHI8 ENTREZGENE, UniProtKB/TrEMBL
  Q3UHR2_MOUSE UniProtKB/TrEMBL
  Q6PGB9_MOUSE UniProtKB/TrEMBL
  Q6ZQD9_MOUSE UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Akap6  A kinase anchor protein 6  Akap6  A kinase (PRKA) anchor protein 6  Symbol and/or name change 5135510 APPROVED