(-)-demecolcine decreases expression ISO RRM2 (Homo sapiens) 6480464 Demecolcine results in decreased expression of RRM2 mRNA CTD PMID:23649840 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane decreases expression ISO RRM2 (Homo sapiens) 6480464 o and p'-DDT results in decreased expression of RRM2 mRNA CTD PMID:18204070 1,1-dichloroethene increases expression EXP 6480464 vinylidene chloride results in increased expression of RRM2 mRNA CTD PMID:26682919 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of RRM2 mRNA CTD PMID:21404309 1-naphthyl isothiocyanate increases expression ISO Rrm2 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of RRM2 mRNA CTD PMID:30723492 17alpha-ethynylestradiol affects expression ISO Rrm2 (Rattus norvegicus) 6480464 Ethinyl Estradiol affects the expression of RRM2 mRNA CTD PMID:17351261 17beta-estradiol increases expression ISO RRM2 (Homo sapiens) 6480464 Estradiol results in increased expression of RRM2 mRNA CTD PMID:16474171 more ... 17beta-estradiol affects expression ISO Rrm2 (Rattus norvegicus) 6480464 Estradiol affects the expression of RRM2 mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of RRM2 mRNA CTD PMID:32741896 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of RRM2 mRNA CTD PMID:15598610 17beta-estradiol multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of RRM2 mRNA CTD PMID:17404688 17beta-estradiol decreases expression ISO RRM2 (Homo sapiens) 6480464 Estradiol results in decreased expression of RRM2 mRNA CTD PMID:20106945 17beta-estradiol 3-benzoate multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of RRM2 mRNA CTD PMID:32741896 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 2 more ... CTD PMID:25510870 and PMID:32352317 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RRM2 (Homo sapiens) 6480464 2 more ... CTD PMID:19095052 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RRM2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of RRM2 mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of RRM2 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of RRM2 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of RRM2 mRNA CTD PMID:21570461 and PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RRM2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of RRM2 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of RRM2 mRNA CTD PMID:19770486 and PMID:25270620 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RRM2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of RRM2 mRNA CTD PMID:21802500 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RRM2 mRNA CTD PMID:15667827 and PMID:19465110 2,4-diaminotoluene increases expression EXP 6480464 2 and 4-diaminotoluene results in increased expression of RRM2 mRNA CTD PMID:20713471 2-butoxyethanol increases expression EXP 6480464 n-butoxyethanol results in increased expression of RRM2 mRNA CTD PMID:19812364 2-palmitoylglycerol increases expression ISO RRM2 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of RRM2 mRNA CTD PMID:37199045 3-chloropropane-1,2-diol increases expression ISO Rrm2 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of RRM2 mRNA CTD PMID:28522335 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of RRM2 mRNA CTD PMID:20713471 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of RRM2 mRNA CTD PMID:18648102 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP 6480464 Oxazolone results in increased expression of RRM2 mRNA CTD PMID:21404309 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of RRM2 mRNA CTD PMID:28973697 4-nitroquinoline N-oxide decreases expression EXP 6480464 4-Nitroquinoline-1-oxide results in decreased expression of RRM2 mRNA CTD PMID:22561872 5-azacytidine multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 5-fluorouracil affects expression ISO RRM2 (Homo sapiens) 6480464 Fluorouracil affects the expression of RRM2 mRNA CTD PMID:15205334 and PMID:16584549 5-fluorouracil affects response to substance ISO RRM2 (Homo sapiens) 6480464 RRM2 protein affects the susceptibility to Fluorouracil CTD PMID:15548681 5-fluorouracil multiple interactions ISO RRM2 (Homo sapiens) 6480464 RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 5-fluorouracil increases expression ISO RRM2 (Homo sapiens) 6480464 Fluorouracil results in increased expression of RRM2 mRNA CTD PMID:16709241 5-fluorouracil decreases expression ISO RRM2 (Homo sapiens) 6480464 Fluorouracil results in decreased expression of RRM2 mRNA CTD PMID:16557594 and PMID:17039268 6-propyl-2-thiouracil increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of RRM2 mRNA CTD PMID:24780913 and PMID:30047161 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:32553695 8-Br-cAMP decreases expression ISO RRM2 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of RRM2 mRNA CTD PMID:22079614 acetamide increases expression ISO Rrm2 (Rattus norvegicus) 6480464 acetamide results in increased expression of RRM2 mRNA CTD PMID:31881176 acrylamide increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Acrylamide results in increased expression of RRM2 mRNA CTD PMID:28959563 acrylamide decreases expression ISO RRM2 (Homo sapiens) 6480464 Acrylamide results in decreased expression of RRM2 mRNA CTD PMID:32763439 aflatoxin B1 affects expression ISO RRM2 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of RRM2 protein CTD PMID:20106945 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of RRM2 mRNA CTD PMID:19770486 all-trans-retinoic acid decreases expression ISO RRM2 (Homo sapiens) 6480464 Tretinoin results in decreased expression of RRM2 mRNA CTD PMID:15498508 and PMID:33167477 amitrole increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Amitrole results in increased expression of RRM2 mRNA CTD PMID:30047161 amphetamine increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Amphetamine results in increased expression of RRM2 mRNA CTD PMID:30779732 antimycin A decreases expression EXP 6480464 Antimycin A results in decreased expression of RRM2 mRNA CTD PMID:19304788 antimycin A increases expression ISO RRM2 (Homo sapiens) 6480464 Antimycin A results in increased expression of RRM2 mRNA CTD PMID:33512557 aristolochic acid A decreases expression ISO RRM2 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of RRM2 mRNA CTD PMID:33212167 aristolochic acid A increases expression ISO RRM2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of RRM2 mRNA and aristolochic acid I results in increased expression of RRM2 protein CTD PMID:33212167 arsenous acid decreases expression ISO RRM2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of RRM2 mRNA and Arsenic Trioxide results in decreased expression of RRM2 protein CTD PMID:25419056 and PMID:26705709 azathioprine decreases expression ISO RRM2 (Homo sapiens) 6480464 Azathioprine results in decreased expression of RRM2 mRNA CTD PMID:22623647 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RRM2 mRNA CTD PMID:17942131 and PMID:19770486 benzo[a]pyrene affects methylation ISO RRM2 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of RRM2 3' UTR and Benzo(a)pyrene affects the methylation of RRM2 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of RRM2 mRNA CTD PMID:27858113 benzo[a]pyrene decreases expression ISO RRM2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of RRM2 mRNA CTD PMID:20064835 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RRM2 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of RRM2 mRNA CTD PMID:26377693 benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of RRM2 mRNA CTD PMID:27858113 bicalutamide decreases expression ISO RRM2 (Homo sapiens) 6480464 bicalutamide results in decreased expression of RRM2 mRNA CTD PMID:15638997 biphenyl-4-amine decreases expression ISO RRM2 (Homo sapiens) 6480464 4-biphenylamine results in decreased expression of RRM2 mRNA CTD PMID:32905825 biphenyl-4-amine multiple interactions ISO RRM2 (Homo sapiens) 6480464 TP53 protein inhibits the reaction [4-biphenylamine results in decreased expression of RRM2 mRNA] CTD PMID:32905825 bis(2-chloroethyl) sulfide decreases expression ISO RRM2 (Homo sapiens) 6480464 Mustard Gas results in decreased expression of RRM2 mRNA CTD PMID:25102026 bisphenol A increases expression ISO RRM2 (Homo sapiens) 6480464 bisphenol A results in increased expression of RRM2 mRNA CTD PMID:16474171 and PMID:31715268 bisphenol A multiple interactions ISO RRM2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of RRM2 gene CTD PMID:31601247 bisphenol A affects expression ISO RRM2 (Homo sapiens) 6480464 bisphenol A affects the expression of RRM2 mRNA CTD PMID:30903817 bisphenol A decreases expression ISO RRM2 (Homo sapiens) 6480464 bisphenol A results in decreased expression of RRM2 mRNA and bisphenol A results in decreased expression of RRM2 protein CTD PMID:29275510 and PMID:37567409 bisphenol A increases methylation ISO Rrm2 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of RRM2 gene CTD PMID:28505145 bisphenol A affects expression ISO Rrm2 (Rattus norvegicus) 6480464 bisphenol A affects the expression of RRM2 mRNA CTD PMID:30816183 and PMID:32145629 bisphenol A decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of RRM2 mRNA CTD PMID:25181051 and PMID:32528016 buspirone decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Buspirone results in decreased expression of RRM2 mRNA CTD PMID:24136188 butanal decreases expression ISO RRM2 (Homo sapiens) 6480464 butyraldehyde results in decreased expression of RRM2 mRNA CTD PMID:26079696 cadmium atom decreases expression ISO RRM2 (Homo sapiens) 6480464 Cadmium results in decreased expression of RRM2 mRNA CTD PMID:21120746 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RRM2 mRNA CTD PMID:37325564 cadmium dichloride decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of RRM2 mRNA CTD PMID:25993096 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of RRM2 mRNA CTD PMID:37325564 cadmium dichloride decreases expression ISO RRM2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of RRM2 mRNA CTD PMID:26314618 caffeine multiple interactions EXP 6480464 Caffeine inhibits the reaction [Camptothecin results in increased expression of RRM2 mRNA] and Caffeine inhibits the reaction [Camptothecin results in increased expression of RRM2 protein] CTD PMID:22403396 calcitriol decreases expression ISO RRM2 (Homo sapiens) 6480464 Calcitriol results in decreased expression of RRM2 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of RRM2 mRNA CTD PMID:21592394 camptothecin increases expression EXP 6480464 Camptothecin results in increased expression of RRM2 mRNA and Camptothecin results in increased expression of RRM2 protein CTD PMID:22403396 camptothecin multiple interactions EXP 6480464 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Camptothecin results in increased expression of RRM2 protein] more ... CTD PMID:22403396 cannabidiol decreases expression ISO RRM2 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of RRM2 mRNA CTD PMID:36519830 carbamazepine affects expression ISO RRM2 (Homo sapiens) 6480464 Carbamazepine affects the expression of RRM2 mRNA CTD PMID:25979313 carbon nanotube affects expression EXP 6480464 Nanotubes and Carbon affects the expression of RRM2 mRNA CTD PMID:25554681 carbon nanotube decreases expression EXP 6480464 Nanotubes and Carbon results in decreased expression of RRM2 mRNA CTD PMID:25620056 carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon analog results in increased expression of RRM2 mRNA CTD PMID:25554681 cefaloridine decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Cephaloridine results in decreased expression of RRM2 mRNA CTD PMID:18500788 celastrol decreases expression ISO RRM2 (Homo sapiens) 6480464 celastrol results in decreased expression of RRM2 mRNA CTD PMID:17010675 choline multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of RRM2 mRNA CTD PMID:28472532 chrysene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of RRM2 mRNA CTD PMID:27858113 ciclopirox decreases activity EXP 6480464 ciclopirox results in decreased activity of RRM2 protein CTD PMID:19589922 ciguatoxin CTX1B affects expression EXP 6480464 Ciguatoxins affects the expression of RRM2 mRNA CTD PMID:18353800 cisplatin multiple interactions ISO RRM2 (Homo sapiens) 6480464 BRCA1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased activity of and results in increased phosphorylation of CHEK1 protein]]] more ... CTD PMID:21875941 cisplatin increases expression ISO RRM2 (Homo sapiens) 6480464 Cisplatin results in increased expression of RRM2 mRNA CTD PMID:27594783 and PMID:33545341 cisplatin decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of RRM2 mRNA CTD PMID:22023808 cobalt atom multiple interactions ISO RRM2 (Homo sapiens) 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of RRM2 mRNA CTD PMID:23052192 cobalt dichloride decreases expression ISO RRM2 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of RRM2 mRNA CTD PMID:19320972 and PMID:19376846 copper atom multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of RRM2 mRNA and [NSC 689534 binds to Copper] which results in decreased expression of RRM2 mRNA CTD PMID:20971185 and PMID:30911355 copper atom increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Copper results in increased expression of RRM2 mRNA CTD PMID:22465980 copper(0) multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of RRM2 mRNA and [NSC 689534 binds to Copper] which results in decreased expression of RRM2 mRNA CTD PMID:20971185 and PMID:30911355 copper(0) increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Copper results in increased expression of RRM2 mRNA CTD PMID:22465980 coumarin affects phosphorylation ISO RRM2 (Homo sapiens) 6480464 coumarin affects the phosphorylation of RRM2 protein CTD PMID:35688186 coumestrol multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 coumestrol increases expression ISO RRM2 (Homo sapiens) 6480464 Coumestrol results in increased expression of RRM2 mRNA CTD PMID:19167446 crocidolite asbestos decreases expression ISO RRM2 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of RRM2 mRNA CTD PMID:29523930 CU-O LINKAGE decreases expression ISO RRM2 (Homo sapiens) 6480464 cupric oxide results in decreased expression of RRM2 mRNA CTD PMID:22077320 Cuprizon increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Cuprizone results in increased expression of RRM2 mRNA CTD PMID:26577399 cyanocob(III)alamin multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA] CTD PMID:22403396 cyclophosphamide multiple interactions ISO RRM2 (Homo sapiens) 6480464 RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of RRM2 mRNA CTD PMID:17942131 and PMID:19770486 cyclosporin A affects expression ISO RRM2 (Homo sapiens) 6480464 Cyclosporine affects the expression of RRM2 mRNA CTD PMID:25562108 cyclosporin A decreases expression ISO RRM2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of RRM2 mRNA CTD PMID:19159671 more ... cytarabine increases expression ISO RRM2 (Homo sapiens) 6480464 Cytarabine results in increased expression of RRM2 mRNA CTD PMID:19194470 decabromodiphenyl ether decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in decreased expression of RRM2 mRNA CTD PMID:23640034 decabromodiphenyl ether increases expression ISO Rrm2 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of RRM2 mRNA CTD PMID:23914054 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of RRM2 mRNA CTD PMID:22733784 diallyl trisulfide decreases expression ISO RRM2 (Homo sapiens) 6480464 diallyl trisulfide results in decreased expression of RRM2 mRNA CTD PMID:34995734 diarsenic trioxide decreases expression ISO RRM2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of RRM2 mRNA and Arsenic Trioxide results in decreased expression of RRM2 protein CTD PMID:25419056 and PMID:26705709 dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of RRM2 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions ISO RRM2 (Homo sapiens) 6480464 N-methyl-delta-3 more ... CTD PMID:36828243 dibutyl phthalate increases expression ISO RRM2 (Homo sapiens) 6480464 Dibutyl Phthalate results in increased expression of RRM2 mRNA CTD PMID:36828243 dibutyl phthalate decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of RRM2 mRNA CTD PMID:21266533 diethyl maleate increases expression ISO Rrm2 (Rattus norvegicus) 6480464 diethyl maleate results in increased expression of RRM2 mRNA CTD PMID:21161181 diethyl maleate increases expression ISO RRM2 (Homo sapiens) 6480464 diethyl maleate results in increased expression of RRM2 mRNA CTD PMID:33545341 diethylstilbestrol increases expression ISO RRM2 (Homo sapiens) 6480464 Diethylstilbestrol results in increased expression of RRM2 mRNA CTD PMID:36621641 dimethylarsinic acid increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Cacodylic Acid results in increased expression of RRM2 mRNA CTD PMID:37567419 dioxygen multiple interactions EXP 6480464 [Iron co-treated with Oxygen] binds to RRM2 protein CTD PMID:16829694 dioxygen decreases expression ISO RRM2 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of RRM2 mRNA CTD PMID:26516004 doxorubicin affects expression ISO RRM2 (Homo sapiens) 6480464 Doxorubicin affects the expression of RRM2 mRNA CTD PMID:15205334 doxorubicin decreases expression ISO RRM2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of RRM2 mRNA CTD PMID:29803840 and PMID:30031762 doxorubicin multiple interactions ISO RRM2 (Homo sapiens) 6480464 RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 Enterolactone multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of RRM2 mRNA CTD PMID:19167446 epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of RRM2 mRNA CTD PMID:35436446 erythromycin estolate increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Erythromycin Estolate results in increased expression of RRM2 mRNA CTD PMID:24412560 erythromycin estolate decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Erythromycin Estolate results in decreased expression of RRM2 mRNA CTD PMID:24412560 ethanol decreases expression ISO RRM2 (Homo sapiens) 6480464 Ethanol results in decreased expression of RRM2 mRNA CTD PMID:23378141 finasteride increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Finasteride results in increased expression of RRM2 mRNA CTD PMID:24136188 fipronil decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 fipronil results in decreased expression of RRM2 mRNA CTD PMID:34044035 folic acid multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of RRM2 mRNA CTD PMID:24657277 folic acid multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 FR900359 decreases phosphorylation ISO RRM2 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of RRM2 protein CTD PMID:37730182 fulvestrant multiple interactions ISO RRM2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of RRM2 gene CTD PMID:31601247 furan increases expression ISO Rrm2 (Rattus norvegicus) 6480464 furan results in increased expression of RRM2 mRNA CTD PMID:25539665 gamma-tocopherol increases expression EXP 6480464 Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 gedunin decreases expression ISO RRM2 (Homo sapiens) 6480464 gedunin results in decreased expression of RRM2 mRNA CTD PMID:17010675 gemcitabine affects response to substance ISO RRM2 (Homo sapiens) 6480464 RRM2 protein affects the susceptibility to Gemcitabine CTD PMID:26894857 gemcitabine multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Gemcitabine results in decreased susceptibility to Gemcitabine] which results in increased expression of RRM2 protein CTD PMID:25189999 genistein increases expression ISO RRM2 (Homo sapiens) 6480464 Genistein results in increased expression of RRM2 mRNA CTD PMID:16474171 and PMID:20884965 genistein decreases expression ISO RRM2 (Homo sapiens) 6480464 Genistein results in decreased expression of RRM2 mRNA CTD PMID:22228119 glycidol decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 glycidol results in decreased expression of RRM2 mRNA CTD PMID:24395379 glycine betaine decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Betaine results in decreased expression of RRM2 mRNA CTD PMID:26391144 glycine betaine multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 hydroxyurea decreases activity EXP 6480464 Hydroxyurea results in decreased activity of RRM2 protein CTD PMID:22403396 indole-3-methanol multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RRM2 mRNA CTD PMID:22129741 iron atom multiple interactions EXP 6480464 [Iron co-treated with Oxygen] binds to RRM2 protein CTD PMID:16829694 iron dichloride increases expression ISO RRM2 (Homo sapiens) 6480464 ferrous chloride results in increased expression of RRM2 mRNA CTD PMID:35984750 iron(0) multiple interactions EXP 6480464 [Iron co-treated with Oxygen] binds to RRM2 protein CTD PMID:16829694 ivermectin decreases expression ISO RRM2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of RRM2 protein CTD PMID:32959892 ketamine decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Ketamine results in decreased expression of RRM2 mRNA CTD PMID:20080153 ketoconazole increases expression ISO RRM2 (Homo sapiens) 6480464 Ketoconazole results in increased expression of RRM2 mRNA CTD PMID:36621641 L-methionine multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 leflunomide decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 leflunomide results in decreased expression of RRM2 mRNA CTD PMID:24136188 leflunomide decreases expression ISO RRM2 (Homo sapiens) 6480464 leflunomide results in decreased expression of RRM2 mRNA CTD PMID:28988120 levofloxacin decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Levofloxacin results in decreased expression of RRM2 mRNA CTD PMID:24136188 lidocaine increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Lidocaine results in increased expression of RRM2 mRNA CTD PMID:35283115 lipopolysaccharide affects expression ISO RRM2 (Homo sapiens) 6480464 Lipopolysaccharides affects the expression of RRM2 mRNA CTD PMID:28070326 lipopolysaccharide multiple interactions ISO RRM2 (Homo sapiens) 6480464 Plant Extracts affects the reaction [Lipopolysaccharides affects the expression of RRM2 mRNA] CTD PMID:28070326 lucanthone decreases expression ISO RRM2 (Homo sapiens) 6480464 Lucanthone results in decreased expression of RRM2 mRNA CTD PMID:21148553 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA] CTD PMID:22403396 lycopene increases expression ISO RRM2 (Homo sapiens) 6480464 lycopene results in increased expression of RRM2 mRNA CTD PMID:16886892 MeIQx increases expression ISO RRM2 (Homo sapiens) 6480464 2-amino-3 more ... CTD PMID:20816883 metformin increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Metformin results in increased expression of RRM2 mRNA CTD PMID:31324951 methamphetamine decreases expression ISO RRM2 (Homo sapiens) 6480464 Methamphetamine results in decreased expression of RRM2 mRNA CTD PMID:25290377 methamphetamine decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Methamphetamine results in decreased expression of RRM2 mRNA and Methamphetamine results in decreased expression of RRM2 protein CTD PMID:28341135 methimazole increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Methimazole results in increased expression of RRM2 mRNA CTD PMID:30047161 methotrexate affects expression EXP 6480464 Methotrexate affects the expression of RRM2 mRNA CTD PMID:18502557 methotrexate decreases expression ISO RRM2 (Homo sapiens) 6480464 Methotrexate results in decreased expression of RRM2 mRNA CTD PMID:24657277 methotrexate multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of RRM2 mRNA CTD PMID:24657277 methyl methanesulfonate increases expression ISO RRM2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of RRM2 mRNA CTD PMID:23649840 methylseleninic acid affects expression ISO RRM2 (Homo sapiens) 6480464 methylselenic acid affects the expression of RRM2 mRNA CTD PMID:14617803 miconazole increases expression EXP 6480464 Miconazole results in increased expression of RRM2 mRNA CTD PMID:27462272 mifepristone multiple interactions EXP 6480464 7-hydroxystaurosporine promotes the reaction [Mifepristone inhibits the reaction [Progesterone results in increased expression of RRM2 protein]] more ... CTD PMID:22403396 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA CTD PMID:25566086 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of RRM2 mRNA CTD PMID:17475336 N-methyl-4-phenylpyridinium decreases expression ISO RRM2 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of RRM2 mRNA CTD PMID:24810058 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RRM2 (Homo sapiens) 6480464 [[Methylnitronitrosoguanidine results in increased phosphorylation of and results in increased stability of and results in increased expression of E2F3 protein] which results in increased expression of RRM2 mRNA] inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of H2AX protein modified form] more ... CTD PMID:26921499 N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO RRM2 (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased expression of RRM2 mRNA CTD PMID:26921499 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of RRM2 mRNA CTD PMID:17854601 N-nitrosodiethylamine multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RRM2 mRNA CTD PMID:22129741 N-nitrosodiethylamine increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of RRM2 mRNA CTD PMID:19638242 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:24535843 N-Nitrosopyrrolidine decreases expression ISO RRM2 (Homo sapiens) 6480464 N-Nitrosopyrrolidine results in decreased expression of RRM2 mRNA CTD PMID:32234424 nefazodone decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 nefazodone results in decreased expression of RRM2 mRNA CTD PMID:24136188 nickel atom increases expression ISO RRM2 (Homo sapiens) 6480464 Nickel results in increased expression of RRM2 mRNA CTD PMID:25583101 niclosamide decreases expression ISO RRM2 (Homo sapiens) 6480464 Niclosamide results in decreased expression of RRM2 mRNA CTD PMID:28284560 nimesulide decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 nimesulide results in decreased expression of RRM2 mRNA CTD PMID:24136188 oxaliplatin multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of RRM2 mRNA CTD PMID:25729387 oxaliplatin decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 oxaliplatin results in decreased expression of RRM2 mRNA CTD PMID:25729387 ozone increases expression EXP 6480464 Ozone results in increased expression of RRM2 mRNA CTD PMID:19555225 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of RRM2 mRNA more ... CTD PMID:25658374 and PMID:34911549 ozone decreases expression EXP 6480464 Ozone results in decreased expression of RRM2 mRNA CTD PMID:24336422 paclitaxel multiple interactions ISO RRM2 (Homo sapiens) 6480464 RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 palbociclib decreases expression ISO RRM2 (Homo sapiens) 6480464 palbociclib results in decreased expression of RRM2 mRNA CTD PMID:22869556 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of RRM2 mRNA CTD PMID:17942131 paracetamol decreases expression ISO RRM2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of RRM2 mRNA CTD PMID:29067470 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of RRM2 mRNA CTD PMID:24126418 PCB138 multiple interactions EXP 6480464 [2 more ... CTD PMID:25510870 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of RRM2 mRNA CTD PMID:37995155 perfluorononanoic acid decreases expression ISO RRM2 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of RRM2 mRNA CTD PMID:32588087 perfluorooctanoic acid decreases expression ISO RRM2 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of RRM2 mRNA CTD PMID:23978341 and PMID:36326898 phenformin decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Phenformin results in decreased expression of RRM2 mRNA CTD PMID:31324951 phenobarbital multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of RRM2 mRNA more ... CTD PMID:19482888 more ... phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of RRM2 mRNA CTD PMID:19482888 more ... phenobarbital affects expression ISO RRM2 (Homo sapiens) 6480464 Phenobarbital affects the expression of RRM2 mRNA CTD PMID:19159669 PhIP increases expression ISO Rrm2 (Rattus norvegicus) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of RRM2 mRNA CTD PMID:29877212 phytoestrogen increases expression ISO RRM2 (Homo sapiens) 6480464 Phytoestrogens results in increased expression of RRM2 mRNA CTD PMID:18310284 picoxystrobin increases expression ISO RRM2 (Homo sapiens) 6480464 picoxystrobin results in increased expression of RRM2 mRNA CTD PMID:33512557 pinosylvin decreases expression ISO RRM2 (Homo sapiens) 6480464 pinosylvin results in decreased expression of RRM2 mRNA CTD PMID:23333577 piperonyl butoxide increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Piperonyl Butoxide results in increased expression of RRM2 mRNA CTD PMID:22484513 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of RRM2 mRNA CTD PMID:18301758 more ... piroxicam decreases expression ISO RRM2 (Homo sapiens) 6480464 Piroxicam results in decreased expression of RRM2 mRNA CTD PMID:21858171 potassium dichromate increases expression ISO RRM2 (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of RRM2 protein CTD PMID:23718831 pregnenolone 16alpha-carbonitrile increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of RRM2 mRNA CTD PMID:30047161 progesterone multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Progesterone co-treated with Estradiol] results in decreased expression of RRM2 mRNA CTD PMID:17404688 progesterone increases expression EXP 6480464 Progesterone results in increased expression of RRM2 mRNA and Progesterone results in increased expression of RRM2 protein CTD PMID:22403396 progesterone multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Progesterone results in increased expression of RRM2 mRNA] more ... CTD PMID:22403396 progesterone decreases expression ISO RRM2 (Homo sapiens) 6480464 Progesterone results in decreased expression of RRM2 mRNA CTD PMID:21795739 progesterone increases expression ISO RRM2 (Homo sapiens) 6480464 Progesterone results in increased expression of RRM2 mRNA CTD PMID:18070364 propanal decreases expression ISO RRM2 (Homo sapiens) 6480464 propionaldehyde results in decreased expression of RRM2 mRNA CTD PMID:26079696 propiconazole increases expression EXP 6480464 propiconazole results in increased expression of RRM2 mRNA CTD PMID:21278054 quercetin decreases expression ISO RRM2 (Homo sapiens) 6480464 Quercetin results in decreased expression of RRM2 mRNA CTD PMID:21632981 resveratrol decreases expression ISO RRM2 (Homo sapiens) 6480464 resveratrol results in decreased expression of RRM2 mRNA CTD PMID:15767336 resveratrol multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of RRM2 mRNA CTD PMID:19167446 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of RRM2 mRNA CTD PMID:19304788 rotenone decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of RRM2 mRNA and Rotenone results in decreased expression of RRM2 protein CTD PMID:28374803 and PMID:35544339 rotenone increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Rotenone results in increased expression of RRM2 mRNA CTD PMID:19013527 SB 431542 multiple interactions ISO RRM2 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of RRM2 protein CTD PMID:37664457 serpentine asbestos increases expression ISO RRM2 (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of RRM2 mRNA CTD PMID:24160326 silicon dioxide increases expression ISO RRM2 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of RRM2 mRNA CTD PMID:25895662 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of RRM2 mRNA CTD PMID:29341224 silicon dioxide increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of RRM2 mRNA CTD PMID:22431001 silicon dioxide decreases expression ISO RRM2 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of RRM2 mRNA and Silicon Dioxide results in decreased expression of RRM2 mRNA CTD PMID:23806026 and PMID:25351596 sodium arsenite decreases expression ISO RRM2 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of RRM2 mRNA and sodium arsenite results in decreased expression of RRM2 protein CTD PMID:20371982 more ... sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of RRM2 mRNA CTD PMID:37682722 sodium arsenite affects expression ISO RRM2 (Homo sapiens) 6480464 sodium arsenite affects the expression of RRM2 mRNA CTD PMID:29301061 and PMID:34032870 sodium arsenite increases expression ISO RRM2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of RRM2 mRNA CTD PMID:28595984 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of RRM2 mRNA CTD PMID:22155349 sodium dichromate affects expression ISO Rrm2 (Rattus norvegicus) 6480464 sodium bichromate affects the expression of RRM2 mRNA CTD PMID:22110744 Soman increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Soman results in increased expression of RRM2 mRNA CTD PMID:19281266 sulfadimethoxine increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Sulfadimethoxine results in increased expression of RRM2 mRNA CTD PMID:30047161 sulindac sulfide decreases expression ISO RRM2 (Homo sapiens) 6480464 sulindac sulfide results in decreased expression of RRM2 mRNA CTD PMID:12734198 sunitinib decreases expression ISO RRM2 (Homo sapiens) 6480464 Sunitinib results in decreased expression of RRM2 mRNA CTD PMID:31533062 tamibarotene affects expression ISO RRM2 (Homo sapiens) 6480464 tamibarotene affects the expression of RRM2 mRNA CTD PMID:15498508 tebufenpyrad increases expression ISO RRM2 (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of RRM2 mRNA CTD PMID:33512557 testosterone multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of RRM2 mRNA CTD PMID:21592394 testosterone decreases expression EXP 6480464 Testosterone deficiency results in decreased expression of RRM2 mRNA CTD PMID:33848595 testosterone multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of RRM2 mRNA CTD PMID:32741896 testosterone decreases expression ISO RRM2 (Homo sapiens) 6480464 Testosterone results in decreased expression of RRM2 mRNA CTD PMID:21592394 tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of RRM2 mRNA CTD PMID:17484886 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of RRM2 mRNA CTD PMID:27339419 more ... tetraphene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of RRM2 mRNA CTD PMID:27858113 thalidomide multiple interactions ISO RRM2 (Homo sapiens) 6480464 [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 thapsigargin decreases expression ISO RRM2 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of RRM2 mRNA CTD PMID:22378314 thioacetamide increases expression ISO Rrm2 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of RRM2 mRNA CTD PMID:23411599 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of RRM2 mRNA CTD PMID:23557971 titanium dioxide increases expression ISO Rrm2 (Rattus norvegicus) 6480464 titanium dioxide results in increased expression of RRM2 mRNA CTD PMID:30012374 titanium dioxide affects expression EXP 6480464 titanium dioxide affects the expression of RRM2 mRNA CTD PMID:17656681 tocopherol increases expression EXP 6480464 Tocopherols results in increased expression of RRM2 mRNA CTD PMID:17056531 toluene 2,4-diisocyanate increases expression EXP 6480464 Toluene 2 and 4-Diisocyanate results in increased expression of RRM2 mRNA CTD PMID:21404309 topotecan decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 Topotecan results in decreased expression of RRM2 mRNA CTD PMID:25729387 topotecan multiple interactions ISO Rrm2 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of RRM2 mRNA CTD PMID:25729387 trans-pinosylvin decreases expression ISO RRM2 (Homo sapiens) 6480464 pinosylvin results in decreased expression of RRM2 mRNA CTD PMID:23333577 Tributyltin oxide decreases expression EXP 6480464 bis(tri-n-butyltin)oxide results in decreased expression of RRM2 mRNA CTD PMID:17942131 Tributyltin oxide decreases phosphorylation EXP 6480464 bis(tri-n-butyltin)oxide results in decreased phosphorylation of RRM2 protein CTD PMID:22174045 triclosan decreases expression ISO RRM2 (Homo sapiens) 6480464 Triclosan results in decreased expression of RRM2 mRNA CTD PMID:30510588 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of RRM2 mRNA CTD PMID:19042947 triptonide decreases expression EXP 6480464 triptonide results in decreased expression of RRM2 mRNA CTD PMID:33045310 triticonazole increases expression ISO Rrm2 (Rattus norvegicus) 6480464 triticonazole results in increased expression of RRM2 mRNA CTD PMID:36084822 troglitazone decreases expression ISO RRM2 (Homo sapiens) 6480464 troglitazone results in decreased expression of RRM2 mRNA CTD PMID:19140230 trovafloxacin decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 trovafloxacin results in decreased expression of RRM2 mRNA CTD PMID:24136188 trovafloxacin decreases expression EXP 6480464 trovafloxacin results in decreased expression of RRM2 mRNA CTD PMID:35537566 Tungsten carbide multiple interactions ISO RRM2 (Homo sapiens) 6480464 [tungsten carbide co-treated with Cobalt] results in increased expression of RRM2 mRNA CTD PMID:23052192 tunicamycin decreases expression ISO RRM2 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of RRM2 mRNA CTD PMID:22378314 valdecoxib decreases expression ISO Rrm2 (Rattus norvegicus) 6480464 valdecoxib results in decreased expression of RRM2 mRNA CTD PMID:24136188 valproic acid increases methylation ISO RRM2 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of RRM2 gene CTD PMID:29154799 valproic acid affects expression ISO RRM2 (Homo sapiens) 6480464 Valproic Acid affects the expression of RRM2 mRNA CTD PMID:25979313 valproic acid decreases expression ISO RRM2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of RRM2 mRNA CTD PMID:19101580 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of RRM2 mRNA CTD PMID:21427059 vincaleukoblastine affects response to substance ISO RRM2 (Homo sapiens) 6480464 RRM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 vincristine decreases expression ISO RRM2 (Homo sapiens) 6480464 Vincristine results in decreased expression of RRM2 mRNA CTD PMID:23649840 zinc atom multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 zinc(0) multiple interactions EXP 6480464 [Methionine co-treated with Choline co-treated with Folic Acid co-treated with Betaine co-treated with Vitamin B 12 co-treated with Zinc co-treated with Phenobarbital] results in increased expression of RRM2 mRNA CTD PMID:33549593 zoledronic acid decreases expression ISO RRM2 (Homo sapiens) 6480464 zoledronic acid results in decreased expression of RRM2 mRNA CTD PMID:24714768