Nek2 (NIMA (never in mitosis gene a)-related expressed kinase 2) - Rat Genome Database

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Gene: Nek2 (NIMA (never in mitosis gene a)-related expressed kinase 2) Mus musculus
Analyze
Symbol: Nek2
Name: NIMA (never in mitosis gene a)-related expressed kinase 2
RGD ID: 1551349
MGI Page MGI
Description: Enables protein kinase activity. Acts upstream of or within several processes, including blastocyst development; mitotic nuclear division; and negative regulation of DNA binding activity. Located in condensed nuclear chromosome; midbody; and spindle pole. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and respiratory system. Human ortholog(s) of this gene implicated in retinitis pigmentosa 67. Orthologous to human NEK2 (NIMA related kinase 2); INTERACTS WITH 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA617254; C77054; Nek2 kinase; never in mitosis A-related kinase 2; NIMA - related expressed kinase 2; NIMA-related expressed kinase 2; NIMA-related kinase 2; nimA-related protein kinase 2; serine/threonine-protein kinase Nek2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm19130  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,552,487 - 191,565,161 (+)NCBIGRCm39mm39
GRCm39 Ensembl1191,553,556 - 191,565,162 (+)Ensembl
GRCm381191,821,449 - 191,833,049 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,821,444 - 191,833,050 (+)EnsemblGRCm38mm10GRCm38
MGSCv371193,645,352 - 193,656,928 (+)NCBIGRCm37mm9NCBIm37
MGSCv361193,522,177 - 193,533,657 (+)NCBImm8
Celera1198,772,491 - 198,784,119 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
3-methylcholanthrene  (EXP)
4-hydroxynon-2-enal  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (EXP,ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (ISO)
antimycin A  (ISO)
arsenite(3-)  (EXP)
atrazine  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
chloroprene  (EXP)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cryptolepine  (ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP,ISO)
Deguelin  (ISO)
diazinon  (ISO)
dichloroacetic acid  (EXP)
dicrotophos  (ISO)
dorsomorphin  (ISO)
elemental selenium  (ISO)
etoposide  (ISO)
fenpyroximate  (ISO)
fulvestrant  (ISO)
furan  (ISO)
geraniol  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
leflunomide  (EXP,ISO)
lucanthone  (ISO)
MeIQx  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nitrofen  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
pentachlorophenol  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
succimer  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tremolite asbestos  (EXP)
Tributyltin oxide  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:8346215   PMID:9187143   PMID:9434622   PMID:9583679   PMID:10349636   PMID:10393247   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11785960   PMID:11897712  
PMID:11911479   PMID:11923207   PMID:12221103   PMID:12477932   PMID:14668482   PMID:14697346   PMID:15123655   PMID:15479717   PMID:15611654   PMID:15893606   PMID:16141072   PMID:16141073  
PMID:17274640   PMID:19117032   PMID:20360068   PMID:20569513   PMID:20718755   PMID:21677750   PMID:21873635   PMID:22560297   PMID:23708664   PMID:23727203   PMID:24194600   PMID:24206222  
PMID:24214971   PMID:25485281   PMID:26220856   PMID:26320076   PMID:26410627   PMID:26496610   PMID:27694478   PMID:30626697   PMID:30635555   PMID:31034758   PMID:33256298   PMID:34050187  


Genomics

Comparative Map Data
Nek2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,552,487 - 191,565,161 (+)NCBIGRCm39mm39
GRCm39 Ensembl1191,553,556 - 191,565,162 (+)Ensembl
GRCm381191,821,449 - 191,833,049 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,821,444 - 191,833,050 (+)EnsemblGRCm38mm10GRCm38
MGSCv371193,645,352 - 193,656,928 (+)NCBIGRCm37mm9NCBIm37
MGSCv361193,522,177 - 193,533,657 (+)NCBImm8
Celera1198,772,491 - 198,784,119 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.94NCBI
NEK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1211,658,657 - 211,675,630 (-)EnsemblGRCh38hg38GRCh38
GRCh381211,658,256 - 211,675,621 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371211,831,598 - 211,848,963 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361209,902,745 - 209,915,590 (-)NCBINCBI36hg18NCBI36
Build 341208,224,516 - 208,237,362NCBI
Celera1185,063,198 - 185,076,042 (-)NCBI
Cytogenetic Map1q32.3NCBI
HuRef1182,509,044 - 182,526,419 (-)NCBIHuRef
CHM1_11213,104,002 - 213,121,393 (-)NCBICHM1_1
Nek2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.213103,405,818 - 103,419,063 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl13103,405,819 - 103,419,051 (+)Ensembl
Rnor_6.013110,511,546 - 110,524,750 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,511,668 - 110,522,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013115,071,708 - 115,084,946 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,895,671 - 107,908,904 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113108,084,908 - 108,096,196 (+)NCBI
Celera13102,845,789 - 102,858,739 (+)NCBICelera
Cytogenetic Map13q27NCBI
Nek2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,553,819 - 5,566,361 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554065,553,661 - 5,563,648 (+)NCBIChiLan1.0ChiLan1.0
NEK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11192,088,393 - 192,105,737 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,092,885 - 192,105,737 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01187,225,947 - 187,243,605 (-)NCBIMhudiblu_PPA_v0panPan3
NEK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1710,039,617 - 10,052,511 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl710,040,187 - 10,052,512 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha79,617,334 - 9,630,223 (-)NCBI
ROS_Cfam_1.079,745,394 - 9,758,577 (-)NCBI
UMICH_Zoey_3.179,668,208 - 9,681,172 (-)NCBI
UNSW_CanFamBas_1.079,770,376 - 9,783,529 (-)NCBI
UU_Cfam_GSD_1.079,894,933 - 9,908,005 (-)NCBI
Nek2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,442,747 - 64,455,130 (+)NCBI
SpeTri2.0NW_0049365571,683,027 - 1,695,410 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,547,084 - 131,560,527 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,547,044 - 131,560,527 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,585,644 - 144,599,144 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NEK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,816,929 - 17,847,348 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,829,546 - 17,842,463 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605518,353,967 - 18,371,748 (+)NCBIVero_WHO_p1.0
Nek2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477117,334,782 - 17,351,609 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
Nek2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371193,653,421 - 193,653,900UniSTSGRCm37
MGSCv3712117,173,326 - 117,173,763UniSTSGRCm37
Celera1198,780,608 - 198,781,087UniSTS
Cytogenetic Map1H6UniSTS
cM Map1103.0UniSTS
AF007247  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381191,832,249 - 191,832,355UniSTSGRCm38
MGSCv371193,656,128 - 193,656,234UniSTSGRCm37
Celera1198,783,327 - 198,783,433UniSTS
Cytogenetic Map1H6UniSTS
cM Map1103.0UniSTS
Whitehead/MRC_RH12440.83UniSTS
RH124524  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381191,831,761 - 191,831,891UniSTSGRCm38
MGSCv371193,655,640 - 193,655,770UniSTSGRCm37
Celera1198,782,841 - 198,782,971UniSTS
Cytogenetic Map1H6UniSTS
cM Map1103.0UniSTS
RH126090  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381823,986,512 - 23,986,724UniSTSGRCm38
GRCm381191,832,718 - 191,832,929UniSTSGRCm38
MGSCv371193,656,597 - 193,656,808UniSTSGRCm37
MGSCv371824,145,013 - 24,145,225UniSTSGRCm37
Celera1824,476,586 - 24,476,798UniSTS
Celera1198,783,796 - 198,783,999UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map18A2UniSTS
cM Map1103.0UniSTS
BE688013  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381191,820,476 - 191,820,557UniSTSGRCm38
MGSCv371193,644,355 - 193,644,436UniSTSGRCm37
Celera1198,771,494 - 198,771,575UniSTS
Cytogenetic Map1H6UniSTS
cM Map1103.0UniSTS
Whitehead/MRC_RH12440.83UniSTS
Nek2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H6UniSTS
Nek2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1H6UniSTS
Nek2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381191,829,542 - 191,830,021UniSTSGRCm38
GRCm3812115,935,115 - 115,935,552UniSTSGRCm38
MGSCv3712117,173,326 - 117,173,763UniSTSGRCm37
MGSCv371193,653,421 - 193,653,900UniSTSGRCm37
Celera1198,780,608 - 198,781,087UniSTS
Cytogenetic Map12F2UniSTS
Cytogenetic Map1H6UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301652Cpfd2_mcerebellum pattern fissures (mouse)Not determined1172571254195471971Mouse
1301596Elnt_mescape latencies during navigation task (mouse)Not determined1162317638194429220Mouse
1559024Zit1_mzinc induced tolerance 1 (mouse)Not determined1167730317195471971Mouse
1302158Fembrs5_mfemur breaking strength 5 (mouse)Not determined1167730317195471971Mouse
1558802Skmw6_mskeletal muscle weight 6 (mouse)Not determined1168222387195471971Mouse
1302023Orch4_mautoimmune orchitis resistance 4 (mouse)Not determined1175529010195471971Mouse
1301431Pcho1_mplasma cholesterol 1 (mouse)Not determined1159435007193435127Mouse
1300842Sle9_msystematic lupus erythematosus susceptibility 9 (mouse)Not determined1158641251192641372Mouse
1357620Aaj1_manxiety in A/J 1 (mouse)Not determined1181004752192168463Mouse
1357692Axtq1_manxiety QTL 1 (mouse)Not determined1181004752192168463Mouse
4141483Femwf7_mfemur work to failure 7 (mouse)Not determined167730317195471971Mouse
1300727Mptp1_mMPTP sensitivity 1 (mouse)Not determined1171804480192998742Mouse
1357732Tbbmd1_mtotal body bone mineral density 1 (mouse)Not determined1172250913195471971Mouse
1301339Hdlq15_mHDL QTL 15 (mouse)Not determined1166092111195471971Mouse
1301202Yaa4_mY-linked autoimmune acceleration 4 (mouse)Not determined1158641251192641372Mouse
1301251Scc3_mcolon tumor susceptibility 3 (mouse)Not determined1168481626195471971Mouse
1301132Mors1_mmodifier of obesity related sterility 1 (mouse)Not determined1170647303195471971Mouse
1300823Ath9_matherosclerosis 9 (mouse)Not determined1160285202194285317Mouse
1301632Bw8q1_mbody weight at 8 weeks QTL 1 (mouse)Not determined1161373696195373830Mouse
10043863Swrl5_mSWR lupus locus 5 (mouse)Not determined1172571254195471971Mouse
10402498Lmr20_mleishmaniasis resistance 20 (mouse)Not determined1158641251192641372Mouse
11049575Lmr8b_mleishmaniasis resistance 8b (mouse)1172571254195471971Mouse
12880426V25Dq2_mvitamin D inactive form serum level QTL 2 (mouse)1172800000195471971Mouse
11059558Lmr20c_mleishmaniasis resistance 20c (mouse)1158641251192641372Mouse
11532690Sluc37_msusceptibility to lung cancer 37 (mouse)1175641251194429220Mouse
12880429V25Dq1_mvitamin D inactive form serum level QTL 1 (mouse)1172900000195471971Mouse
11059557Lmr20a_mleishmaniasis resistance 20a (mouse)1158641251192641372Mouse
12790987Tgl5_mtriglyceride 5 (mouse)1160269591194269591Mouse
11059556Lmr20b_mleishmaniasis resistance 20b (mouse)1158641251192641372Mouse
12790988Phdlc5_mplasma HDL cholesterol 5 (mouse)9160269591194269591Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1012
Count of miRNA genes:600
Interacting mature miRNAs:725
Transcripts:ENSMUST00000027931, ENSMUST00000126446, ENSMUST00000136733, ENSMUST00000150839
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006497123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF007247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF013166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK142346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK171387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC057576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF738658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U95610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000027931   ⟹   ENSMUSP00000027931
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1191,553,556 - 191,565,162 (+)Ensembl
GRCm38.p6 Ensembl1191,821,444 - 191,833,050 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126446
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1191,553,622 - 191,560,404 (+)Ensembl
GRCm38.p6 Ensembl1191,821,510 - 191,828,292 (+)Ensembl
RefSeq Acc Id: ENSMUST00000136733
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1191,559,260 - 191,562,100 (+)Ensembl
GRCm38.p6 Ensembl1191,827,148 - 191,829,988 (+)Ensembl
RefSeq Acc Id: ENSMUST00000150839
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1191,554,294 - 191,557,937 (+)Ensembl
GRCm38.p6 Ensembl1191,822,182 - 191,825,825 (+)Ensembl
RefSeq Acc Id: NM_010892   ⟹   NP_035022
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391191,553,585 - 191,565,161 (+)NCBI
GRCm381191,821,473 - 191,833,049 (+)NCBI
MGSCv371193,645,352 - 193,656,928 (+)RGD
Celera1198,772,491 - 198,784,119 (+)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006497123   ⟹   XP_006497186
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391191,552,487 - 191,565,161 (+)NCBI
GRCm381191,821,449 - 191,833,049 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035022   ⟸   NM_010892
- UniProtKB: O35942 (UniProtKB/Swiss-Prot),   Q6PFG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006497186   ⟸   XM_006497123
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000027931   ⟸   ENSMUST00000027931
Protein Domains
Protein kinase

Promoters
RGD ID:6876122
Promoter ID:EPDNEW_M1512
Type:initiation region
Name:Nek2_1
Description:Mus musculus NIMA -related expressed kinase 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381191,821,514 - 191,821,574EPDNEW
RGD ID:6818164
Promoter ID:MM_KWN:3317
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Lung
Transcripts:OTTMUST00000066791,   OTTMUST00000066792,   OTTMUST00000066793,   UC007ECY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361193,645,181 - 193,645,681 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109359 AgrOrtholog
Ensembl Genes ENSMUSG00000026622 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000027931 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027931 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18005 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:109359 ENTREZGENE
NCBI Gene 18005 ENTREZGENE
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nek2 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NEK2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TF15_MOUSE UniProtKB/TrEMBL
  Q6PFG1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BP64_MOUSE UniProtKB/TrEMBL
  Q91Z18_MOUSE UniProtKB/TrEMBL
  Q921N9_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35959 UniProtKB/Swiss-Prot
  Q3TPD7 UniProtKB/Swiss-Prot