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Gene: Deaf1 (DEAF1, transcription factor) Mus musculus
Symbol: Deaf1
Name: DEAF1, transcription factor
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including behavioral fear response; chordate embryonic development; and visual learning. Localizes to the cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 24. Is expressed in several structures, including bone; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human DEAF1 (DEAF1 transcription factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; carbon nanotube; chromium(6+).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AU042387; C230009B13Rik; deformed epidermal autoregulatory factor 1 (Drosophila); deformed epidermal autoregulatory factor 1 homolog; nuclear DEAF-1-related transcriptional regulator; NUDR; suppressin
Homo sapiens (human) : DEAF1 (DEAF1 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Deaf1 (DEAF1 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Deaf1 (DEAF1 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : DEAF1 (DEAF1 transcription factor)
Canis lupus familiaris (dog) : DEAF1 (DEAF1 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Deaf1 (DEAF1 transcription factor)
Sus scrofa (pig) : DEAF1 (DEAF1 transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm387141,297,176 - 141,338,869 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377148,483,075 - 148,524,682 (-)NCBIGRCm37mm9NCBIm37
MGSCv367141,148,505 - 141,178,895 (-)NCBImm8
Celera7141,090,924 - 141,132,561 (-)NCBICelera
Cytogenetic Map7 F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Deaf1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731971
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.