Pilrb2 (paired immunoglobin-like type 2 receptor beta 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Pilrb2 (paired immunoglobin-like type 2 receptor beta 2) Mus musculus
Analyze
Symbol: Pilrb2
Name: paired immunoglobin-like type 2 receptor beta 2
RGD ID: 1614689
MGI Page MGI
Description: Predicted to enable MHC class I protein binding activity. Predicted to be located in cell periphery and membrane. Orthologous to human PILRB (paired immunoglobin like type 2 receptor beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activating receptor PILR-beta-2; EG545812; paired immunoglobulin-like type 2 receptor beta-2
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,864,083 - 137,870,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,864,089 - 137,870,077 (-)EnsemblGRCm39 Ensembl
GRCm385137,865,821 - 137,871,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,865,827 - 137,871,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,307,057 - 138,312,986 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,095,617 - 138,101,546 (-)NCBIMGSCv36mm8
Celera5134,852,637 - 134,858,090 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 43 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pilrb2Mouse(+)-catechin multiple interactionsISOPILRB (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of PILRB mRNACTDPMID:24763279
Pilrb2Mouse2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsEXP 6480464[2 more ...CTDPMID:25510870
Pilrb2Mouse2,2',5,5'-tetrachlorobiphenyl multiple interactionsEXP 6480464[2 more ...CTDPMID:25510870
Pilrb2Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPILRB (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of PILRB mRNACTDPMID:19684285
Pilrb2Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPILRB (Homo sapiens)6480464[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of PILRB mRNACTDPMID:19684285
Pilrb2Mouse2,4-D multiple interactionsEXP 6480464[lard co-treated with Cholesterol more ...CTDPMID:37567420
Pilrb2Mouse2-hydroxypropanoic acid increases expressionISOPILRB (Homo sapiens)6480464Lactic Acid results in increased expression of PILRB mRNACTDPMID:30851411
Pilrb2Mouse2-methylcholine affects expressionISOPILRB (Homo sapiens)6480464beta-methylcholine affects the expression of PILRB mRNACTDPMID:21179406
Pilrb2Mouse3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of PILRB2 mRNACTDPMID:20188158
Pilrb2Mouse4,4'-sulfonyldiphenol decreases expressionISOPILRB (Homo sapiens)6480464bisphenol S results in decreased expression of PILRB mRNACTDPMID:27685785
Pilrb2Mouse4-hydroxyphenyl retinamide increases expressionEXP 6480464Fenretinide results in increased expression of PILRB mRNACTDPMID:28973697
Pilrb2Mouseacrolein multiple interactionsISOPILRB (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PILRB mRNA more ...CTDPMID:32699268 and PMID:32845096
Pilrb2Mouseaflatoxin B1 increases methylationISOPILRB (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of PILRB geneCTDPMID:27153756
Pilrb2Mousealdehydo-D-glucose multiple interactionsEXP 6480464[lard co-treated with Cholesterol more ...CTDPMID:37567420
Pilrb2Mousealpha-pinene multiple interactionsISOPILRB (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of PILRB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of PILRB mRNACTDPMID:32699268
Pilrb2Mouseatrazine decreases expressionISOPILRB (Homo sapiens)6480464Atrazine results in decreased expression of PILRB mRNACTDPMID:22378314
Pilrb2Mousebenzo[a]pyrene decreases expressionEXP 6480464Benzo(a)pyrene results in decreased expression of PILRB mRNA and Benzo(a)pyrene results in decreased expression of PILRB2 mRNACTDPMID:21569818
Pilrb2Mousebenzo[a]pyrene increases methylationISOPILRB (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of PILRB 5' UTRCTDPMID:27901495
Pilrb2Mousebisphenol A decreases expressionISOPILRB (Homo sapiens)6480464bisphenol A results in decreased expression of PILRB mRNACTDPMID:25047013 and PMID:27685785
Pilrb2Mousebisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of PILRB2 promoterCTDPMID:27312807

1 to 20 of 43 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pilrb2Mousecell periphery located_inIEAARBA:ARBA000274432290270 UniProtGO_REF:0000117
Pilrb2Mousemembrane located_inIEAARBA:ARBA000287632290270 UniProtGO_REF:0000117

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pilrb2MouseMHC class I protein binding enablesIBAPANTHER:PTN000399488 and MGI:24505322290270 GO_CentralGO_REF:0000033
Pilrb2Mouseprotein binding enablesISOUniProtKB:P293509068941 PMID:10660620UniProtPMID:10660620


#
Reference Title
Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16926269   PMID:21873635  



Pilrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,864,083 - 137,870,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,864,089 - 137,870,077 (-)EnsemblGRCm39 Ensembl
GRCm385137,865,821 - 137,871,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,865,827 - 137,871,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,307,057 - 138,312,986 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,095,617 - 138,101,546 (-)NCBIMGSCv36mm8
Celera5134,852,637 - 134,858,090 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.85NCBI
PILRB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,358,117 - 100,367,831 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,352,176 - 100,367,831 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,955,740 - 99,965,454 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,771,673 - 99,803,388 (+)NCBINCBI36Build 36hg18NCBI36
Celera794,685,426 - 94,695,252 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,588,903 - 94,598,990 (+)NCBIHuRef
CHM1_1799,886,201 - 99,896,029 (+)NCBICHM1_1
T2T-CHM13v2.07101,598,196 - 101,607,910 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,315,712 - 99,325,540 (+)NCBI

.

.
Variants in Pilrb2
545 total Variants

Predicted Target Of
Summary Value
Count of predictions:335
Count of miRNA genes:283
Interacting mature miRNAs:304
Transcripts:ENSMUST00000164886
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 27 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse

1 to 10 of 27 rows
34.MMHAP64FRD10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,868,804 - 137,868,970UniSTSGRCm38
GRCm385137,855,104 - 137,855,270UniSTSGRCm38
MGSCv375138,310,032 - 138,310,198UniSTSGRCm37
MGSCv375138,296,332 - 138,296,498UniSTSGRCm37
Cytogenetic Map5G2UniSTS
Whitehead_YAC5 UniSTS







Ensembl Acc Id: ENSMUST00000164886   ⟹   ENSMUSP00000131233
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,091 - 137,870,020 (-)Ensembl
GRCm38.p6 Ensembl5137,865,829 - 137,871,758 (-)Ensembl
Ensembl Acc Id: ENSMUST00000196162   ⟹   ENSMUSP00000143064
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,869,969 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,871,707 (-)Ensembl
Ensembl Acc Id: ENSMUST00000197411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,865,192 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,866,930 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198024   ⟹   ENSMUSP00000143366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,866,912 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,868,650 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199247   ⟹   ENSMUSP00000142830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,869,347 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,871,085 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199773   ⟹   ENSMUSP00000142492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,869,421 - 137,870,077 (-)Ensembl
GRCm38.p6 Ensembl5137,871,159 - 137,871,815 (-)Ensembl
RefSeq Acc Id: NM_001024932   ⟹   NP_001020103
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,091 - 137,870,020 (-)NCBI
GRCm385137,865,829 - 137,871,758 (-)NCBI
MGSCv375138,307,057 - 138,312,986 (-)RGD
Celera5134,852,637 - 134,858,090 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001384202   ⟹   NP_001371131
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,083 - 137,870,020 (-)NCBI
GRCm385137,865,821 - 137,871,758 (-)NCBI
Sequence:
RefSeq Acc Id: NR_169051
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,083 - 137,870,020 (-)NCBI
GRCm385137,865,821 - 137,871,758 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004942542
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,317 - 137,870,083 (-)NCBI
Sequence:
1 to 10 of 10 rows
Protein RefSeqs NP_001020103 (Get FASTA)   NCBI Sequence Viewer  
  NP_001371131 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI47406 (Get FASTA)   NCBI Sequence Viewer  
  AAI47407 (Get FASTA)   NCBI Sequence Viewer  
  AAX39496 (Get FASTA)   NCBI Sequence Viewer  
  BAC29442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000131233
  ENSMUSP00000131233.2
  ENSMUSP00000143064
GenBank Protein Q2YFS1 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_001020103   ⟸   NM_001024932
- Peptide Label: isoform 1 precursor
- UniProtKB: Q2YFS1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001371131   ⟸   NM_001384202
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A0G2JF84 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000131233   ⟸   ENSMUST00000164886
Ensembl Acc Id: ENSMUSP00000143366   ⟸   ENSMUST00000198024
Ensembl Acc Id: ENSMUSP00000142492   ⟸   ENSMUST00000199773

Name Modeler Protein Id AA Range Protein Structure
AF-Q2YFS1-F1-model_v2 AlphaFold Q2YFS1 1-225 view protein structure

RGD ID:6888476
Promoter ID:EPDNEW_M7689
Type:initiation region
Name:Pilrb2_1
Description:Mus musculus paired immunoglobin-like type 2 receptor beta 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385137,871,722 - 137,871,782EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000066682 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000164886 ENTREZGENE
  ENSMUST00000164886.2 UniProtKB/Swiss-Prot
  ENSMUST00000196162 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Immunoregulatory_rcpt-like UniProtKB/Swiss-Prot
MGD MGI:2450535 ENTREZGENE
NCBI Gene 545812 ENTREZGENE
PANTHER PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR UniProtKB/Swiss-Prot
  PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA-RELATED UniProtKB/Swiss-Prot
PhenoGen Pilrb2 PhenoGen
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A0G2JDT4_MOUSE UniProtKB/TrEMBL
  A0A0G2JEM6_MOUSE UniProtKB/TrEMBL
  A0A0G2JF84 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JFZ6_MOUSE UniProtKB/TrEMBL
  PILB2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
1 to 19 of 19 rows