Pilrb2 (paired immunoglobin-like type 2 receptor beta 2) - Rat Genome Database

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Gene: Pilrb2 (paired immunoglobin-like type 2 receptor beta 2) Mus musculus
Analyze
Symbol: Pilrb2
Name: paired immunoglobin-like type 2 receptor beta 2
RGD ID: 1614689
MGI Page MGI
Description: Predicted to enable MHC class I protein binding activity. Predicted to be located in cell periphery and membrane. Orthologous to human PILRA (paired immunoglobin like type 2 receptor alpha) and PILRB (paired immunoglobin like type 2 receptor beta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: activating receptor PILR-beta-2; EG545812; paired immunoglobulin-like type 2 receptor beta-2
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,864,083 - 137,870,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,864,089 - 137,870,077 (-)EnsemblGRCm39 Ensembl
GRCm385137,865,821 - 137,871,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,865,827 - 137,871,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,307,057 - 138,312,986 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,095,617 - 138,101,546 (-)NCBIMGSCv36mm8
Celera5134,852,637 - 134,858,090 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell periphery  (IEA)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16926269   PMID:21873635  


Genomics

Comparative Map Data
Pilrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,864,083 - 137,870,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,864,089 - 137,870,077 (-)EnsemblGRCm39 Ensembl
GRCm385137,865,821 - 137,871,758 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,865,827 - 137,871,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,307,057 - 138,312,986 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,095,617 - 138,101,546 (-)NCBIMGSCv36mm8
Celera5134,852,637 - 134,858,090 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.85NCBI
PILRB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,358,117 - 100,367,831 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,352,176 - 100,367,831 (+)EnsemblGRCh38hg38GRCh38
GRCh37799,955,740 - 99,965,454 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,771,673 - 99,803,388 (+)NCBINCBI36Build 36hg18NCBI36
Celera794,685,426 - 94,695,252 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,588,903 - 94,598,990 (+)NCBIHuRef
CHM1_1799,886,201 - 99,896,029 (+)NCBICHM1_1
T2T-CHM13v2.07101,598,196 - 101,607,910 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,315,712 - 99,325,540 (+)NCBI

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:335
Count of miRNA genes:283
Interacting mature miRNAs:304
Transcripts:ENSMUST00000164886
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse

Markers in Region
34.MMHAP64FRD10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385137,868,804 - 137,868,970UniSTSGRCm38
GRCm385137,855,104 - 137,855,270UniSTSGRCm38
MGSCv375138,310,032 - 138,310,198UniSTSGRCm37
MGSCv375138,296,332 - 138,296,498UniSTSGRCm37
Cytogenetic Map5G2UniSTS
Whitehead_YAC5 UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000164886   ⟹   ENSMUSP00000131233
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,091 - 137,870,020 (-)Ensembl
GRCm38.p6 Ensembl5137,865,829 - 137,871,758 (-)Ensembl
Ensembl Acc Id: ENSMUST00000196162   ⟹   ENSMUSP00000143064
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,869,969 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,871,707 (-)Ensembl
Ensembl Acc Id: ENSMUST00000197411
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,865,192 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,866,930 (-)Ensembl
Ensembl Acc Id: ENSMUST00000198024   ⟹   ENSMUSP00000143366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,866,912 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,868,650 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199247   ⟹   ENSMUSP00000142830
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,864,089 - 137,869,347 (-)Ensembl
GRCm38.p6 Ensembl5137,865,827 - 137,871,085 (-)Ensembl
Ensembl Acc Id: ENSMUST00000199773   ⟹   ENSMUSP00000142492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5137,869,421 - 137,870,077 (-)Ensembl
GRCm38.p6 Ensembl5137,871,159 - 137,871,815 (-)Ensembl
RefSeq Acc Id: NM_001024932   ⟹   NP_001020103
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,091 - 137,870,020 (-)NCBI
GRCm385137,865,829 - 137,871,758 (-)NCBI
MGSCv375138,307,057 - 138,312,986 (-)RGD
Celera5134,852,637 - 134,858,090 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001384202   ⟹   NP_001371131
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,083 - 137,870,020 (-)NCBI
GRCm385137,865,821 - 137,871,758 (-)NCBI
Sequence:
RefSeq Acc Id: NR_169051
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,083 - 137,870,020 (-)NCBI
GRCm385137,865,821 - 137,871,758 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004942542
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395137,864,317 - 137,870,083 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001020103   ⟸   NM_001024932
- Peptide Label: isoform 1 precursor
- UniProtKB: Q2YFS1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001371131   ⟸   NM_001384202
- Peptide Label: isoform 2 precursor
- UniProtKB: A0A0G2JF84 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000131233   ⟸   ENSMUST00000164886
Ensembl Acc Id: ENSMUSP00000143366   ⟸   ENSMUST00000198024
Ensembl Acc Id: ENSMUSP00000142492   ⟸   ENSMUST00000199773
Ensembl Acc Id: ENSMUSP00000142830   ⟸   ENSMUST00000199247
Ensembl Acc Id: ENSMUSP00000143064   ⟸   ENSMUST00000196162

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q2YFS1-F1-model_v2 AlphaFold Q2YFS1 1-225 view protein structure

Promoters
RGD ID:6888476
Promoter ID:EPDNEW_M7689
Type:initiation region
Name:Pilrb2_1
Description:Mus musculus paired immunoglobin-like type 2 receptor beta 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385137,871,722 - 137,871,782EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2450535 AgrOrtholog
Ensembl Genes ENSMUSG00000066682 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000164886 ENTREZGENE
  ENSMUST00000164886.2 UniProtKB/Swiss-Prot
  ENSMUST00000196162 ENTREZGENE
  ENSMUST00000196162.5 UniProtKB/TrEMBL
  ENSMUST00000198024.5 UniProtKB/TrEMBL
  ENSMUST00000199247.2 UniProtKB/TrEMBL
  ENSMUST00000199773.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Immunoregulatory_rcpt-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2450535 ENTREZGENE
NCBI Gene 545812 ENTREZGENE
PANTHER PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR BETA-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pilrb2 PhenoGen
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JDT4_MOUSE UniProtKB/TrEMBL
  A0A0G2JEM6_MOUSE UniProtKB/TrEMBL
  A0A0G2JF84 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JFZ6_MOUSE UniProtKB/TrEMBL
  PILB2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE