Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cd8a (CD8 antigen, alpha chain) Mus musculus
Symbol: Cd8a
Name: CD8 antigen, alpha chain
Description: Exhibits identical protein binding activity. Involved in several processes, including cytotoxic T cell differentiation; defense response to virus; and positive regulation of calcium-mediated signaling. Localizes to the external side of plasma membrane. Is expressed in several structures, including endocrine gland; exocrine gland; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human CD8A (CD8a molecule); PARTICIPATES IN interleukin-12 signaling pathway; antigen processing and presentation pathway; primary immunodeficiency pathway; INTERACTS WITH (D-Ala(2)-mephe(4)-gly-ol(5))enkephalin; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BB154331; Ly-2; Ly-35; Ly-B; Lyt-2; Lyt-2.1 lymphocyte differentiation antigen (AA at 100); T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein Lyt-2
Homo sapiens (human) : CD8A (CD8a molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd8a (CD8a molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd8a (CD8a molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD8A (CD8a molecule)
Canis lupus familiaris (dog) : CD8A (CD8a molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd8a (CD8a molecule)
Sus scrofa (pig) : CD8A (CD8a molecule)
Chlorocebus sabaeus (green monkey) : CD8A (CD8a molecule)
Heterocephalus glaber (naked mole-rat) : Cd8a (CD8a molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl671,373,427 - 71,379,173 (+)Ensembl
GRCm38671,373,427 - 71,379,171 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37671,323,421 - 71,329,165 (+)NCBIGRCm37mm9NCBIm37
MGSCv36671,302,936 - 71,308,680 (+)NCBImm8
Celera673,452,794 - 73,458,537 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd8a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10317
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.