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Gene: Nbr1 (NBR1, autophagy cargo receptor) Mus musculus
Symbol: Nbr1
Name: NBR1, autophagy cargo receptor
Description: Exhibits mitogen-activated protein kinase binding activity. Involved in negative regulation of osteoblast differentiation; regulation of bone mineralization; and regulation of stress-activated MAPK cascade. Localizes to late endosome and phagophore assembly site. Colocalizes with autophagosome. Is expressed in central nervous system; genitourinary system; heart; and retina. Orthologous to human NBR1 (NBR1 autophagy cargo receptor); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: membrane component chromosome 17 surface marker 2 homolog; mKIAA0049; neighbor of Brca1 gene 1; neighbor of BRCA1 gene 1 protein; next to BRCA1 gene 1 protein; next to the Brca1
Homo sapiens (human) : NBR1 (NBR1 autophagy cargo receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nbr1 (NBR1, autophagy cargo receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nbr1 (NBR1 autophagy cargo receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : NBR1 (NBR1 autophagy cargo receptor)
Canis lupus familiaris (dog) : NBR1 (NBR1 autophagy cargo receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nbr1 (NBR1 autophagy cargo receptor)
Sus scrofa (pig) : NBR1 (NBR1 autophagy cargo receptor)
Chlorocebus sabaeus (African green monkey) : NBR1 (NBR1 autophagy cargo receptor)
Heterocephalus glaber (naked mole-rat) : Nbr1 (NBR1 autophagy cargo receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11101,552,149 - 101,581,951 (+)EnsemblGRCm38mm10GRCm38
GRCm3811101,552,107 - 101,581,951 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711101,414,172 - 101,443,259 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611101,368,948 - 101,398,035 (+)NCBImm8
Celera11113,240,071 - 113,269,159 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1165.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nbr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69459
Created: 2001-11-27
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.