Trp63 (transformation related protein 63) - Rat Genome Database

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Gene: Trp63 (transformation related protein 63) Mus musculus
Analyze
Symbol: Trp63
Name: transformation related protein 63
RGD ID: 736710
MGI Page MGI
Description: Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and identical protein binding activity. Involved in several processes, including establishment of skin barrier; negative regulation of intracellular estrogen receptor signaling pathway; and regulation of epidermal cell division. Acts upstream of or within several processes, including animal organ development; embryonic limb morphogenesis; and morphogenesis of a polarized epithelium. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; sensory organ; and surface ectoderm. Used to study ankyloblepharon-ectodermal defects-cleft lip/palate syndrome; bladder exstrophy; ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3; and gastroesophageal reflux disease. Human ortholog(s) of this gene implicated in several diseases, including ADULT syndrome; EEC syndrome (multiple); ectodermal dysplasia (multiple); orofacial cleft 8; and split hand-foot malformation 4. Orthologous to human TP63 (tumor protein p63).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI462811; delta; Ket; MGC115972; p51/p; P51/P63; p6; P63; p7; P73l; TAp; Tp63; transformation-related protein 63; Trp5; Trp53rp1; tumor protein 63; tumor protein p73-like
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391625,502,513 - 25,710,838 (+)NCBIGRCm39mm39
GRCm39 Ensembl1625,502,513 - 25,710,852 (+)Ensembl
GRCm381625,683,763 - 25,892,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1625,683,763 - 25,892,102 (+)EnsemblGRCm38mm10GRCm38
MGSCv371625,683,851 - 25,892,174 (+)NCBIGRCm37mm9NCBIm37
MGSCv361625,717,291 - 25,807,429 (+)NCBImm8
Celera1626,227,614 - 26,435,704 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1617.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenocarcinoma  (ISO)
ADULT syndrome  (ISO)
amenorrhea  (ISO)
ankyloblepharon-ectodermal defects-cleft lip/palate syndrome  (IEA,ISO)
bladder exstrophy  (IEA)
bladder exstrophy-epispadias-cloacal exstrophy complex  (ISO)
breast disease  (ISO)
Breast Neoplasms  (EXP)
carcinoma  (ISO)
cervix uteri carcinoma in situ  (ISO)
cleft lip  (ISO)
cleft palate  (ISO)
Colorectal Neoplasms  (ISO)
Congenital Foot Deformities  (ISO)
Congenital Hand Deformities  (ISO)
Congenital Limb Deformities  (ISO)
Corneal Injuries  (IEP)
Craniofacial Abnormalities  (ISO)
ectodermal dysplasia  (ISO)
ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3  (IEA,ISO)
EEC syndrome  (IMP,ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Neoplasms  (EXP)
Female Urogenital Diseases  (ISO)
gastroesophageal reflux disease  (IEA)
genetic disease  (ISO)
Limb-Mammary Syndrome  (ISO)
lung adenocarcinoma  (ISO)
Lung Neoplasms  (ISO)
Multiple Abnormalities  (ISO)
muscular dystrophy  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
orofacial cleft 8  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
primary ovarian insufficiency  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (EXP,IEP,ISO)
Prostatic Neoplasms  (EXP,IEP,ISO)
Rapp-Hodgkin syndrome  (ISO)
schizophrenia  (ISO)
Skin Abnormalities  (ISO)
split hand-foot malformation  (ISO)
split hand-foot malformation 4  (ISO)
squamous cell carcinoma  (ISO)
squamous cell neoplasm  (ISO)
Sweat Gland Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dibromoethane  (EXP)
1,2-dichloroethane  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-dichloroaniline  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-vinylcyclohexene dioxide  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antimonite  (ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butan-1-ol  (ISO)
butane-2,3-dione  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (EXP)
chloropicrin  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
emodin  (EXP)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ethylenediaminetetraacetic acid  (ISO)
eugenol  (ISO)
formaldehyde  (ISO)
Fusarenone X  (EXP)
genistein  (ISO)
glycidol  (EXP)
graphite  (EXP)
hydroxyurea  (EXP)
isobutanol  (ISO)
kaempferol  (ISO)
ketoconazole  (EXP)
lactacystin  (ISO)
lead diacetate  (EXP)
leptomycin B  (ISO)
lithium chloride  (ISO)
luteolin  (ISO)
melphalan  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
myricetin  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel dichloride  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
progesterone  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
quinolin-8-ol  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
anatomical structure formation involved in morphogenesis  (IMP)
animal organ morphogenesis  (IMP)
apoptotic process  (TAS)
cell aging  (IMP)
cell differentiation  (IMP)
cell population proliferation  (IMP)
cellular response to DNA damage stimulus  (ISO)
chromatin remodeling  (IMP)
cloacal septation  (IMP)
cranial skeletal system development  (IMP)
developmental process  (IEA)
ectoderm and mesoderm interaction  (IMP)
embryonic forelimb morphogenesis  (IMP)
embryonic hindlimb morphogenesis  (IMP)
embryonic limb morphogenesis  (IGI,IMP)
epidermal cell differentiation  (IMP)
epidermal cell division  (IMP)
epidermis development  (IMP)
epithelial cell development  (IDA,IMP)
epithelial cell differentiation  (IMP)
establishment of planar polarity  (IDA)
establishment of skin barrier  (IMP)
female genitalia morphogenesis  (IMP)
hair follicle development  (IMP)
hair follicle morphogenesis  (IMP)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (IMP)
keratinocyte differentiation  (IDA)
keratinocyte proliferation  (IDA)
morphogenesis of a polarized epithelium  (IMP)
multicellular organism aging  (IMP)
negative regulation of apoptotic process  (IMP)
negative regulation of cellular senescence  (ISO)
negative regulation of intracellular estrogen receptor signaling pathway  (IMP)
negative regulation of keratinocyte differentiation  (IGI,IMP)
negative regulation of mesoderm development  (IMP)
negative regulation of transcription by RNA polymerase II  (IDA,IEP,IGI,IMP,ISO)
negative regulation of transcription, DNA-templated  (ISO)
neuron apoptotic process  (IMP)
Notch signaling pathway  (IEA)
odontogenesis of dentin-containing tooth  (IMP)
pattern specification process  (IMP)
polarized epithelial cell differentiation  (IMP)
positive regulation of apoptotic signaling pathway  (IDA)
positive regulation of cell cycle G1/S phase transition  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of fibroblast apoptotic process  (ISO)
positive regulation of keratinocyte proliferation  (IGI)
positive regulation of mesenchymal cell proliferation  (IMP)
positive regulation of Notch signaling pathway  (IMP,ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of somatic stem cell population maintenance  (IMP)
positive regulation of transcription by RNA polymerase II  (IDA,IEP,IMP,ISO)
positive regulation of transcription, DNA-templated  (ISO)
post-anal tail morphogenesis  (IMP)
prostate gland development  (IMP)
prostatic bud formation  (IMP)
protein tetramerization  (IEA)
proximal/distal pattern formation  (IMP)
regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IMP)
regulation of epidermal cell division  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
regulation of transcription, DNA-templated  (IEA)
skeletal system development  (IMP)
skin epidermis development  (IMP)
skin morphogenesis  (IMP)
smooth muscle tissue development  (IMP)
spermatogenesis  (ISO)
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development  (IMP)
sympathetic nervous system development  (IMP)
urinary bladder development  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal wall morphology  (IAGP)
abnormal anus morphology  (IAGP)
abnormal apical ectodermal ridge morphology  (IAGP)
abnormal cellular replicative senescence  (IAGP)
abnormal corneal epithelium morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal embryo development  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal epidermis stratum spinosum morphology  (IAGP)
abnormal esophageal epithelium morphology  (IAGP)
abnormal esophageal squamous epithelium morphology  (IAGP)
abnormal esophagus development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal hair follicle development  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal horizontal basal cell of olfactory epithelium morphology  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal keratinocyte differentiation  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal keratinocyte physiology  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal limb bud morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal limb morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal olfactory epithelium morphology  (IAGP)
abnormal olfactory gland morphology  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal primitive urogenital sinus morphology  (IAGP)
abnormal prostate gland branching morphogenesis  (IAGP)
abnormal rectum morphology  (IAGP)
abnormal reproductive system morphology  (IAGP)
abnormal respiratory epithelium morphology  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal septation of the cloaca  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin development  (IAGP)
abnormal skin morphology  (IAGP)
abnormal skin physiology  (IAGP)
abnormal stomach epithelium morphology  (IAGP)
abnormal stomach non-glandular epithelium morphology  (IAGP)
abnormal tongue epithelium morphology  (IAGP)
abnormal tooth development  (IAGP)
abnormal tooth root morphology  (IAGP)
abnormal tracheal ciliated epithelium morphology  (IAGP)
abnormal urinary bladder detrusor smooth muscle morphology  (IAGP)
abnormal urinary bladder urothelium morphology  (IAGP)
abnormal uterine cervix epithelium morphology  (IAGP)
abnormal vagina epithelium morphology  (IAGP)
abnormal ventral body wall morphology  (IAGP)
absent apical ectodermal ridge  (IAGP)
absent carpal bone  (IAGP)
absent epidermis  (IAGP)
absent epidermis stratum corneum  (IAGP)
absent epidermis stratum granulosum  (IAGP)
absent epidermis stratum spinosum  (IAGP)
absent eyelids  (IAGP)
absent gastric milk in neonates  (IAGP)
absent hair follicles  (IAGP)
absent hindlimb  (IAGP)
absent lacrimal glands  (IAGP)
absent limbs  (IAGP)
absent mammary gland  (IAGP)
absent ovary  (IAGP)
absent oviduct  (IAGP)
absent prostate gland  (IAGP)
absent pubic symphysis  (IAGP)
absent radius  (IAGP)
absent salivary gland  (IAGP)
absent sebaceous gland  (IAGP)
absent teeth  (IAGP)
absent tongue squamous epithelium  (IAGP)
absent tooth placode  (IAGP)
absent ulna  (IAGP)
absent urinary bladder urothelium  (IAGP)
absent vibrissae  (IAGP)
acanthosis  (IAGP)
adactyly  (IAGP)
alopecia  (IAGP)
aneuploidy  (IAGP)
blistering  (IAGP)
chromosomal instability  (IAGP)
circling  (IAGP)
cleft palate  (IAGP)
clitoris hypoplasia  (IAGP)
decreased apoptosis  (IAGP)
decreased cell proliferation  (IAGP)
decreased cellular sensitivity to ionizing radiation  (IAGP)
decreased fetal size  (IAGP)
decreased hair follicle number  (IAGP)
decreased keratinocyte proliferation  (IAGP)
dehydration  (IAGP)
dermal-epidermal separation  (IAGP)
distended abdomen  (IAGP)
distended urinary bladder  (IAGP)
early cellular replicative senescence  (IAGP)
ectrodactyly  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
enlarged lymph nodes  (IAGP)
esophagogastric junction metaplasia  (IAGP)
gastric cyst  (IAGP)
gastric metaplasia  (IAGP)
hemorrhage  (IAGP)
impaired skin barrier function  (IAGP)
impaired wound healing  (IAGP)
increased apoptosis  (IAGP)
increased carcinoma incidence  (IAGP)
increased chronic myelocytic leukemia incidence  (IAGP)
increased hemangiosarcoma incidence  (IAGP)
increased histiocytic sarcoma incidence  (IAGP)
increased lung adenocarcinoma incidence  (IAGP)
increased lung adenoma incidence  (IAGP)
increased malignant tumor incidence  (IAGP)
increased mammary adenocarcinoma incidence  (IAGP)
increased metastatic potential  (IAGP)
increased osteosarcoma incidence  (IAGP)
increased rhabdomyosarcoma incidence  (IAGP)
increased salivary gland adenoma incidence  (IAGP)
increased squamous cell carcinoma incidence  (IAGP)
increased susceptibility to infection  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased tumor incidence  (IAGP)
increased urinary bladder transitional cell carcinoma incidence  (IAGP)
intervertebral disk degeneration  (IAGP)
kidney cyst  (IAGP)
kidney inflammation  (IAGP)
kyphosis  (IAGP)
lordokyphosis  (IAGP)
monodactyly  (IAGP)
nail dystrophy  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
paralysis  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
premature aging  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
rectal prolapse  (IAGP)
rectovaginal fistula  (IAGP)
ruffled hair  (IAGP)
shiny skin  (IAGP)
short limbs  (IAGP)
skin lesions  (IAGP)
small limb buds  (IAGP)
small mandible  (IAGP)
small maxilla  (IAGP)
small tail bud  (IAGP)
small uterus  (IAGP)
spontaneous skin ulceration  (IAGP)
supernumerary teeth  (IAGP)
syndactyly  (IAGP)
thick dermal layer  (IAGP)
thick epidermis  (IAGP)
thick epidermis stratum basale  (IAGP)
thick epidermis stratum spinosum  (IAGP)
thin urinary bladder urothelium  (IAGP)
translucent skin  (IAGP)
umbilical hernia  (IAGP)
urinary bladder exstrophy  (IAGP)
uterine cervix inflammation  (IAGP)
weakness  (IAGP)
weight loss  (IAGP)
wrinkled skin  (IAGP)
References

References - curated
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13. MGD and Homologene mouse data transfer
14. MGD data from the GO Consortium
15. MGD IEA
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19. OMIM Disease Annotation Pipeline
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22. RGD automated import pipeline
23. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. RGD automated import pipeline for gene-chemical interactions
25. South AP, etal., Br J Dermatol. 2002 Feb;146(2):216-20.
26. Stepan A, etal., Rom J Morphol Embryol. 2009;50(3):461-5.
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28. Tuna B, etal., Anal Quant Cytol Histol. 2009 Apr;31(2):118-22.
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Additional References at PubMed
PMID:9315105   PMID:9703973   PMID:9774969   PMID:9799841   PMID:10203277   PMID:10227293   PMID:10227294   PMID:10231571   PMID:10349636   PMID:10657951   PMID:10754563   PMID:11042159  
PMID:11076861   PMID:11106548   PMID:11118893   PMID:11217851   PMID:11470269   PMID:11522642   PMID:11733180   PMID:11747081   PMID:11825686   PMID:11857801   PMID:11932750   PMID:12368184  
PMID:12368193   PMID:12477932   PMID:12702649   PMID:12789272   PMID:12941620   PMID:12951416   PMID:14526104   PMID:14555234   PMID:14729569   PMID:14757276   PMID:14998922   PMID:15033906  
PMID:15189821   PMID:15261144   PMID:15280445   PMID:15361520   PMID:15371305   PMID:15371309   PMID:15375216   PMID:15528198   PMID:15543231   PMID:15585950   PMID:15607981   PMID:15653949  
PMID:15659035   PMID:15716346   PMID:15746257   PMID:15797384   PMID:15837625   PMID:15908775   PMID:15922574   PMID:15982302   PMID:15987773   PMID:15988020   PMID:16007124   PMID:16007185  
PMID:16051706   PMID:16080917   PMID:16081516   PMID:16107615   PMID:16141072   PMID:16141073   PMID:16324689   PMID:16337913   PMID:16342117   PMID:16363065   PMID:16406339   PMID:16410075  
PMID:16466397   PMID:16524929   PMID:16557273   PMID:16601749   PMID:16601753   PMID:16602821   PMID:16618715   PMID:16618808   PMID:16645595   PMID:16714381   PMID:16715076   PMID:16914490  
PMID:16940753   PMID:16998800   PMID:17018588   PMID:17036050   PMID:17041601   PMID:17041603   PMID:17045206   PMID:17050669   PMID:17079275   PMID:17079460   PMID:17079689   PMID:17093266  
PMID:17122775   PMID:17159913   PMID:17164413   PMID:17182369   PMID:17198697   PMID:17224652   PMID:17276340   PMID:17317930   PMID:17360634   PMID:17383628   PMID:17482546   PMID:17522155  
PMID:17603506   PMID:17626181   PMID:17631878   PMID:17653081   PMID:17662267   PMID:17823311   PMID:17846227   PMID:17878916   PMID:18028901   PMID:18159078   PMID:18164684   PMID:18199584  
PMID:18256694   PMID:18275068   PMID:18287559   PMID:18289041   PMID:18292208   PMID:18292212   PMID:18311128   PMID:18326838   PMID:18353300   PMID:18374910   PMID:18410734   PMID:18483491  
PMID:18544451   PMID:18585372   PMID:18586087   PMID:18593557   PMID:18633439   PMID:18634775   PMID:18648642   PMID:18786355   PMID:18849344   PMID:18927586   PMID:18927616   PMID:19038788  
PMID:19092943   PMID:19235715   PMID:19300453   PMID:19303948   PMID:19345189   PMID:19371732   PMID:19403656   PMID:19439425   PMID:19458240   PMID:19461998   PMID:19494829   PMID:19502490  
PMID:19555433   PMID:19570515   PMID:19574443   PMID:19622632   PMID:19631635   PMID:19686689   PMID:19717565   PMID:19749746   PMID:19763140   PMID:19782673   PMID:19783996   PMID:19816568  
PMID:19876067   PMID:19898465   PMID:19946331   PMID:19956733   PMID:20038814   PMID:20043902   PMID:20059953   PMID:20090763   PMID:20105280   PMID:20157559   PMID:20157588   PMID:20161489  
PMID:20211142   PMID:20308292   PMID:20332116   PMID:20335364   PMID:20379195   PMID:20424325   PMID:20424327   PMID:20430747   PMID:20485546   PMID:20498273   PMID:20519941   PMID:20523354  
PMID:20559324   PMID:20658693   PMID:20697379   PMID:20930145   PMID:20962848   PMID:20962855   PMID:20975950   PMID:21042780   PMID:21068065   PMID:21093383   PMID:21098114   PMID:21114965  
PMID:21127199   PMID:21127502   PMID:21136383   PMID:21228373   PMID:21262812   PMID:21267068   PMID:21285247   PMID:21293190   PMID:21295273   PMID:21300779   PMID:21303954   PMID:21307095  
PMID:21309073   PMID:21335238   PMID:21356385   PMID:21402782   PMID:21429982   PMID:21435444   PMID:21438071   PMID:21505443   PMID:21531785   PMID:21558811   PMID:21576089   PMID:21624358  
PMID:21637289   PMID:21677159   PMID:21703447   PMID:21743007   PMID:21750033   PMID:21760596   PMID:21768372   PMID:21799872   PMID:21803035   PMID:21873635   PMID:21897369   PMID:21898690  
PMID:21905163   PMID:21909072   PMID:21912215   PMID:21926108   PMID:21930775   PMID:21965674   PMID:21982232   PMID:21982646   PMID:22027432   PMID:22038471   PMID:22113860   PMID:22117221  
PMID:22153372   PMID:22167068   PMID:22173065   PMID:22178326   PMID:22197488   PMID:22232434   PMID:22240899   PMID:22244744   PMID:22274697   PMID:22421361   PMID:22442009   PMID:22496369  
PMID:22508511   PMID:22560297   PMID:22573176   PMID:22575646   PMID:22662233   PMID:22714890   PMID:22763785   PMID:22922031   PMID:22935613   PMID:22949635   PMID:22949650   PMID:23000175  
PMID:23034632   PMID:23040072   PMID:23108156   PMID:23184966   PMID:23213461   PMID:23219093   PMID:23251530   PMID:23251711   PMID:23300485   PMID:23344544   PMID:23362346   PMID:23406900  
PMID:23449535   PMID:23481305   PMID:23516636   PMID:23553930   PMID:23589895   PMID:23598363   PMID:23608756   PMID:23614751   PMID:23620512   PMID:23686138   PMID:23754280   PMID:23806336  
PMID:23809701   PMID:23830984   PMID:23831572   PMID:23863842   PMID:23867503   PMID:23873029   PMID:23904595   PMID:23906066   PMID:23916850   PMID:23924630   PMID:23924632   PMID:23974039  
PMID:23993789   PMID:24013722   PMID:24038357   PMID:24068956   PMID:24075906   PMID:24127607   PMID:24134540   PMID:24145187   PMID:24146773   PMID:24218621   PMID:24258200   PMID:24260306  
PMID:24260555   PMID:24262428   PMID:24263106   PMID:24274029   PMID:24294373   PMID:24309930   PMID:24337118   PMID:24346698   PMID:24357321   PMID:24360809   PMID:24412575   PMID:24415949  
PMID:24440910   PMID:24449888   PMID:24478334   PMID:24482479   PMID:24503032   PMID:24515437   PMID:24569166   PMID:24590292   PMID:24594519   PMID:24669837   PMID:24692510   PMID:24725274  
PMID:24735878   PMID:24794706   PMID:24809925   PMID:24859845   PMID:24952961   PMID:24982158   PMID:24983500   PMID:24992712   PMID:25043473   PMID:25043474   PMID:25100655   PMID:25133425  
PMID:25146927   PMID:25163637   PMID:25166858   PMID:25168238   PMID:25168241   PMID:25190801   PMID:25191969   PMID:25210499   PMID:25241036   PMID:25249461   PMID:25329657   PMID:25358290  
PMID:25358791   PMID:25383540   PMID:25387952   PMID:25398052   PMID:25409149   PMID:25430793   PMID:25503409   PMID:25516972   PMID:25523394   PMID:25564622   PMID:25567987   PMID:25601450  
PMID:25603931   PMID:25655704   PMID:25668240   PMID:25704602   PMID:25739959   PMID:25790093   PMID:25790853   PMID:25820239   PMID:25827072   PMID:25848986   PMID:25897018   PMID:25912685  
PMID:25968320   PMID:26023097   PMID:26076167   PMID:26115514   PMID:26116174   PMID:26203562   PMID:26235047   PMID:26305958   PMID:26329601   PMID:26359534   PMID:26371508   PMID:26555052  
PMID:26566817   PMID:26652033   PMID:26685160   PMID:26690418   PMID:26711500   PMID:26742488   PMID:26755636   PMID:26768665   PMID:26917450   PMID:26989131   PMID:27019188   PMID:27021569  
PMID:27132513   PMID:27184845   PMID:27300436   PMID:27302476   PMID:27341756   PMID:27511831   PMID:27654891   PMID:27709293   PMID:27716744   PMID:27721240   PMID:27725202   PMID:27770432  
PMID:27807348   PMID:27869165   PMID:27889317   PMID:27910949   PMID:28028137   PMID:28041841   PMID:28052057   PMID:28107452   PMID:28211873   PMID:28253399   PMID:28324176   PMID:28333962  
PMID:28346423   PMID:28400434   PMID:28438836   PMID:28480888   PMID:28505376   PMID:28506465   PMID:28546511   PMID:28589954   PMID:28595999   PMID:28604778   PMID:28617799   PMID:28637720  
PMID:28643456   PMID:28655168   PMID:28688895   PMID:28698625   PMID:28732181   PMID:28737769   PMID:28794159   PMID:28797033   PMID:28817352   PMID:28827394   PMID:28827783   PMID:28859094  
PMID:28898113   PMID:29019984   PMID:29044125   PMID:29078349   PMID:29103953   PMID:29174332   PMID:29174333   PMID:29180475   PMID:29339502   PMID:29361573   PMID:29362488   PMID:29386246  
PMID:29391208   PMID:29396915   PMID:29451339   PMID:29490983   PMID:29520104   PMID:29523849   PMID:29587145   PMID:29632206   PMID:29670083   PMID:29700203   PMID:29716728   PMID:29885760  
PMID:29913133   PMID:29981310   PMID:29988075   PMID:30061411   PMID:30153454   PMID:30189017   PMID:30220568   PMID:30305289   PMID:30366903   PMID:30478225   PMID:30651296   PMID:30696710  
PMID:30701202   PMID:30714224   PMID:30720908   PMID:30745430   PMID:30866939   PMID:30875130   PMID:30910837   PMID:30912742   PMID:30916783   PMID:30944105   PMID:31118233   PMID:31216312  
PMID:31221639   PMID:31345929   PMID:31597917   PMID:31624230   PMID:31631837   PMID:31712410   PMID:31776260   PMID:31794060   PMID:31813798   PMID:31875961   PMID:31943082   PMID:31949138  
PMID:31953387   PMID:32081850   PMID:32179912   PMID:32325033   PMID:32381741   PMID:32385093   PMID:32392534   PMID:32464196   PMID:32572167   PMID:32748407   PMID:32758484   PMID:32866472  
PMID:32878924   PMID:32932139   PMID:33025905   PMID:33056990   PMID:33141892   PMID:33144400   PMID:33159086   PMID:33318148   PMID:33328632   PMID:33428297   PMID:33452256   PMID:33469811  
PMID:33495473   PMID:33515576   PMID:33715275   PMID:33882290   PMID:33906607   PMID:34023861   PMID:34050161   PMID:34445673  


Genomics

Comparative Map Data
Trp63
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391625,502,513 - 25,710,838 (+)NCBIGRCm39mm39
GRCm39 Ensembl1625,502,513 - 25,710,852 (+)Ensembl
GRCm381625,683,763 - 25,892,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1625,683,763 - 25,892,102 (+)EnsemblGRCm38mm10GRCm38
MGSCv371625,683,851 - 25,892,174 (+)NCBIGRCm37mm9NCBIm37
MGSCv361625,717,291 - 25,807,429 (+)NCBImm8
Celera1626,227,614 - 26,435,704 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1617.37NCBI
TP63
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3189,631,389 - 189,897,276 (+)EnsemblGRCh38hg38GRCh38
GRCh383189,596,746 - 189,897,276 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373189,314,535 - 189,615,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363190,831,910 - 191,097,759 (+)NCBINCBI36hg18NCBI36
Celera3187,783,803 - 188,042,610 (+)NCBI
Cytogenetic Map3q28NCBI
HuRef3186,752,882 - 187,012,887 (+)NCBIHuRef
CHM1_13189,312,090 - 189,577,623 (+)NCBICHM1_1
Tp63
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21174,838,858 - 75,049,764 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1174,838,859 - 75,049,398 (-)Ensembl
Rnor_6.01178,234,853 - 78,456,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,234,800 - 78,456,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,262,234 - 82,484,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,900,622 - 77,200,251 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11176,958,211 - 77,257,840 (-)NCBI
Celera1173,744,494 - 73,953,104 (-)NCBICelera
Cytogenetic Map11q22NCBI
Tp63
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542018,176,155 - 18,384,786 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542018,178,639 - 18,384,786 (-)NCBIChiLan1.0ChiLan1.0
TP63
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13195,172,810 - 195,473,085 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3195,199,167 - 195,474,104 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03186,651,879 - 186,918,300 (+)NCBIMhudiblu_PPA_v0panPan3
TP63
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13421,766,861 - 21,985,095 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3421,766,496 - 21,983,046 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3425,860,495 - 26,078,655 (+)NCBI
ROS_Cfam_1.03421,700,749 - 21,919,495 (+)NCBI
ROS_Cfam_1.0 Ensembl3421,700,663 - 21,918,660 (+)Ensembl
UMICH_Zoey_3.13421,716,204 - 21,934,749 (+)NCBI
UNSW_CanFamBas_1.03421,710,660 - 21,927,985 (+)NCBI
UU_Cfam_GSD_1.03421,951,749 - 22,170,136 (+)NCBI
Tp63
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602114,397,903 - 114,613,831 (-)NCBI
SpeTri2.0NW_004936578492,267 - 705,282 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TP63
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13127,116,104 - 127,347,075 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113127,115,990 - 127,347,082 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213136,309,804 - 136,515,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TP63
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11583,861,489 - 84,126,675 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604157,444,595 - 57,708,553 (+)NCBIVero_WHO_p1.0
Tp63
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473067,283,444 - 67,489,808 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AI462811  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,891,676 - 25,891,759UniSTSGRCm38
MGSCv371625,891,762 - 25,891,845UniSTSGRCm37
Celera1626,435,292 - 26,435,375UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Whitehead/MRC_RH16220.27UniSTS
31.MMHAP58FLC4.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,784,079 - 25,784,278UniSTSGRCm38
MGSCv371625,784,165 - 25,784,364UniSTSGRCm37
Celera1626,327,938 - 26,328,137UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Whitehead_YAC16 UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371625,868,269 - 25,871,183UniSTSGRCm37
MGSCv371625,865,002 - 25,865,211UniSTSGRCm37
Celera1626,408,532 - 26,408,741UniSTS
Celera1626,411,799 - 26,414,713UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
cM Map1619.3UniSTS
cM Map1619.3UniSTS
cM Map1619.3UniSTS
AB010152  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,890,490 - 25,890,611UniSTSGRCm38
MGSCv371625,890,576 - 25,890,697UniSTSGRCm37
Celera1626,434,106 - 26,434,227UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Whitehead/MRC_RH16221.52UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,864,916 - 25,865,125UniSTSGRCm38
MGSCv371625,865,002 - 25,865,211UniSTSGRCm37
Celera1626,408,532 - 26,408,741UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128616494Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129856336Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130249113Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130996708Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16350000040000000Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16350000051600000Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16350000064800000Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16400000064800000Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16450000044700000Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16482756438827664Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16595650239956690Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16595650239956690Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16595650239956690Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16595650239956690Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16665914535200846Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16672511565669666Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16731904229406653Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16840730242407302Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16860000091100000Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined161006288144062881Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161203007246030171Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161240654246406653Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161498410348984214Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161570409149704294Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162020057985803938Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162211802156118212Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2295650257773713Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir92-1mmu-miR-92a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19608627
Mir92-2mmu-miR-92a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19608627
Mir203mmu-miR-203-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI18311128
Mir203mmu-miR-203-3pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20216554

Predicted Target Of
Summary Value
Count of predictions:5110
Count of miRNA genes:794
Interacting mature miRNAs:1093
Transcripts:ENSMUST00000040231, ENSMUST00000065523, ENSMUST00000115304, ENSMUST00000115305, ENSMUST00000115306, ENSMUST00000115307, ENSMUST00000115308, ENSMUST00000115310
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB010152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC109213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC113020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF533892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC090649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000040231   ⟹   ENSMUSP00000038117
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,710,852 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,892,102 (+)Ensembl
RefSeq Acc Id: ENSMUST00000065523   ⟹   ENSMUSP00000067005
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,515 - 25,710,837 (+)Ensembl
GRCm38.p6 Ensembl1625,683,765 - 25,892,087 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115304   ⟹   ENSMUSP00000110959
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,686,604 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,867,854 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115305   ⟹   ENSMUSP00000110960
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,695,894 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,877,144 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115306   ⟹   ENSMUSP00000110961
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,710,852 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,892,102 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115307   ⟹   ENSMUSP00000110962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,513 - 25,640,068 (+)Ensembl
GRCm38.p6 Ensembl1625,683,763 - 25,821,318 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115308   ⟹   ENSMUSP00000110963
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,515 - 25,695,894 (+)Ensembl
GRCm38.p6 Ensembl1625,683,765 - 25,877,144 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115310   ⟹   ENSMUSP00000110965
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,515 - 25,710,852 (+)Ensembl
GRCm38.p6 Ensembl1625,683,765 - 25,892,102 (+)Ensembl
RefSeq Acc Id: NM_001127259   ⟹   NP_001120731
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,515 - 25,710,838 (+)NCBI
GRCm381625,683,765 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127260   ⟹   NP_001120732
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,515 - 25,710,838 (+)NCBI
GRCm381625,683,765 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127261   ⟹   NP_001120733
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,515 - 25,695,894 (+)NCBI
GRCm381625,683,765 - 25,877,144 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127262   ⟹   NP_001120734
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,710,838 (+)NCBI
GRCm381625,801,916 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127263   ⟹   NP_001120735
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,695,894 (+)NCBI
GRCm381625,801,916 - 25,877,144 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127264   ⟹   NP_001120736
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,710,838 (+)NCBI
GRCm381625,801,916 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127265   ⟹   NP_001120737
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,695,894 (+)NCBI
GRCm381625,801,916 - 25,877,144 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011641   ⟹   NP_035771
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,710,838 (+)NCBI
GRCm381625,801,916 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522000   ⟹   XP_006522063
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,513 - 25,710,030 (+)NCBI
GRCm381625,683,763 - 25,889,339 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522001   ⟹   XP_006522064
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,513 - 25,708,089 (+)NCBI
GRCm381625,801,763 - 25,889,339 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522002   ⟹   XP_006522065
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,513 - 25,696,648 (+)NCBI
GRCm381625,683,763 - 25,877,898 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001120731 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120732 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120733 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120734 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120735 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120736 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120737 (Get FASTA)   NCBI Sequence Viewer  
  NP_035771 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522063 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522064 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522065 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC62639 (Get FASTA)   NCBI Sequence Viewer  
  AAC62640 (Get FASTA)   NCBI Sequence Viewer  
  AAC62641 (Get FASTA)   NCBI Sequence Viewer  
  AAC62642 (Get FASTA)   NCBI Sequence Viewer  
  AAC62643 (Get FASTA)   NCBI Sequence Viewer  
  AAC62644 (Get FASTA)   NCBI Sequence Viewer  
  AAH90649 (Get FASTA)   NCBI Sequence Viewer  
  AAH92537 (Get FASTA)   NCBI Sequence Viewer  
  AAP87982 (Get FASTA)   NCBI Sequence Viewer  
  AAP87983 (Get FASTA)   NCBI Sequence Viewer  
  AAP87984 (Get FASTA)   NCBI Sequence Viewer  
  AAP87985 (Get FASTA)   NCBI Sequence Viewer  
  AAP87986 (Get FASTA)   NCBI Sequence Viewer  
  AAP87987 (Get FASTA)   NCBI Sequence Viewer  
  BAA32432 (Get FASTA)   NCBI Sequence Viewer  
  BAC33397 (Get FASTA)   NCBI Sequence Viewer  
  BAE23286 (Get FASTA)   NCBI Sequence Viewer  
  EDK97682 (Get FASTA)   NCBI Sequence Viewer  
  EDK97683 (Get FASTA)   NCBI Sequence Viewer  
  EDK97684 (Get FASTA)   NCBI Sequence Viewer  
  O88898 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_035771   ⟸   NM_011641
- Peptide Label: isoform d
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120731   ⟸   NM_001127259
- Peptide Label: isoform a
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120732   ⟸   NM_001127260
- Peptide Label: isoform b
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120733   ⟸   NM_001127261
- Peptide Label: isoform c
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q569E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120734   ⟸   NM_001127262
- Peptide Label: isoform f
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120736   ⟸   NM_001127264
- Peptide Label: isoform e
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q3UVI3 (UniProtKB/TrEMBL),   Q5CZX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120735   ⟸   NM_001127263
- Peptide Label: isoform g
- UniProtKB: Q569E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120737   ⟸   NM_001127265
- Peptide Label: isoform h
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q569E5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522063   ⟸   XM_006522000
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006522065   ⟸   XM_006522002
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006522064   ⟸   XM_006522001
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000067005   ⟸   ENSMUST00000065523
RefSeq Acc Id: ENSMUSP00000038117   ⟸   ENSMUST00000040231
RefSeq Acc Id: ENSMUSP00000110959   ⟸   ENSMUST00000115304
RefSeq Acc Id: ENSMUSP00000110962   ⟸   ENSMUST00000115307
RefSeq Acc Id: ENSMUSP00000110963   ⟸   ENSMUST00000115308
RefSeq Acc Id: ENSMUSP00000110960   ⟸   ENSMUST00000115305
RefSeq Acc Id: ENSMUSP00000110961   ⟸   ENSMUST00000115306
RefSeq Acc Id: ENSMUSP00000110965   ⟸   ENSMUST00000115310
Protein Domains
P53   P53_tetramer   SAM

Promoters
RGD ID:8685876
Promoter ID:EPDNEW_M20969
Type:single initiation site
Name:Trp63_3
Description:Mus musculus transformation related protein 63 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20970  EPDNEW_M20971  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381625,683,763 - 25,683,823EPDNEW
RGD ID:8685878
Promoter ID:EPDNEW_M20970
Type:multiple initiation site
Name:Trp63_1
Description:Mus musculus transformation related protein 63 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20969  EPDNEW_M20971  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381625,801,916 - 25,801,976EPDNEW
RGD ID:8685880
Promoter ID:EPDNEW_M20971
Type:single initiation site
Name:Trp63_2
Description:Mus musculus transformation related protein 63 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20969  EPDNEW_M20970  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381625,865,701 - 25,865,761EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1330810 AgrOrtholog
Ensembl Genes ENSMUSG00000022510 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000038117 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000067005 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110959 UniProtKB/TrEMBL
  ENSMUSP00000110960 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000110961 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000110962 UniProtKB/TrEMBL
  ENSMUSP00000110963 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110965 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000040231 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000065523 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000115304 UniProtKB/TrEMBL
  ENSMUST00000115305 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000115306 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000115307 UniProtKB/TrEMBL
  ENSMUST00000115308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000115310 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53/RUNT-type_TF_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_tetramer_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_tetrameristn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_tumour_suppressor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tp63 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumor-p63_SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22061 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1330810 ENTREZGENE
NCBI Gene 22061 ENTREZGENE
PANTHER PTHR11447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11447:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam P53 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P53_tetramer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trp63 PhenoGen
PRINTS P53SUPPRESSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE P53 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47719 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1K8_MOUSE UniProtKB/TrEMBL
  D3Z7K2_MOUSE UniProtKB/TrEMBL
  O88898 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3UVI3 ENTREZGENE, UniProtKB/TrEMBL
  Q569E5 ENTREZGENE, UniProtKB/TrEMBL
  Q5CZX0 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O88897 UniProtKB/Swiss-Prot
  O88899 UniProtKB/Swiss-Prot
  O89097 UniProtKB/Swiss-Prot
  Q8C826 UniProtKB/Swiss-Prot
  Q9QWY9 UniProtKB/Swiss-Prot
  Q9QWZ0 UniProtKB/Swiss-Prot