Trp63 (transformation related protein 63) - Rat Genome Database

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Gene: Trp63 (transformation related protein 63) Mus musculus
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Symbol: Trp63
Name: transformation related protein 63
RGD ID: 736710
MGI Page MGI
Description: Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and identical protein binding activity. Involved in several processes, including establishment of skin barrier; negative regulation of intracellular estrogen receptor signaling pathway; and regulation of epidermal cell division. Acts upstream of or within several processes, including embryonic morphogenesis; epithelial cell differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system epithelium; and surface ectoderm. Used to study ankyloblepharon-ectodermal defects-cleft lip/palate syndrome; bladder exstrophy; ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3; and gastroesophageal reflux disease. Human ortholog(s) of this gene implicated in several diseases, including ADULT syndrome; EEC syndrome (multiple); ectodermal dysplasia (multiple); orofacial cleft 8; and split hand-foot malformation 4. Orthologous to human TP63 (tumor protein p63).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AI462811; delta; Ket; MGC115972; p51/p; P51/P63; p6; P63; p7; P73l; TAp; Tp63; transformation-related protein 63; Trp5; Trp53rp1; tumor protein 63; tumor protein p73-like
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391625,502,513 - 25,710,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1625,502,513 - 25,710,852 (+)EnsemblGRCm39 Ensembl
GRCm381625,683,763 - 25,892,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1625,683,763 - 25,892,102 (+)EnsemblGRCm38mm10GRCm38
MGSCv371625,683,851 - 25,892,174 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361625,717,291 - 25,807,429 (+)NCBIMGSCv36mm8
Celera1626,227,614 - 26,435,704 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1617.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenocarcinoma  (ISO)
ADULT syndrome  (ISO)
amenorrhea  (ISO)
ankyloblepharon-ectodermal defects-cleft lip/palate syndrome  (IAGP,ISO)
autosomal recessive nonsyndromic deafness  (ISO)
bladder exstrophy  (IAGP)
bladder exstrophy-epispadias-cloacal exstrophy complex  (ISO)
bone development disease  (ISO)
breast disease  (ISO)
Breast Neoplasms  (EXP)
carcinoma  (ISO)
cervix uteri carcinoma in situ  (ISO)
cleft lip  (ISO)
Cleft Lip with or without Cleft Palate, Nonsyndromic, 8  (ISO)
cleft palate  (ISO)
Colorectal Neoplasms  (ISO)
Congenital Foot Deformities  (ISO)
Congenital Hand Deformities  (ISO)
Congenital Limb Deformities  (ISO)
Corneal Injuries  (IEP)
Craniofacial Abnormalities  (ISO)
ectodermal dysplasia  (ISO)
ectrodactyly, ectodermal dysplasia, and cleft lip-palate syndrome 3  (IAGP,ISO)
EEC syndrome  (IMP,ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Neoplasms  (EXP)
Female Urogenital Diseases  (ISO)
fissured tongue  (ISO)
gastroesophageal reflux disease  (IAGP)
genetic disease  (ISO)
Limb-Mammary Syndrome  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
Lung Neoplasms  (ISO)
Multiple Abnormalities  (ISO)
muscular dystrophy  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
orofacial cleft 8  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
primary ovarian insufficiency  (ISO)
prostate cancer  (ISO)
prostate carcinoma in situ  (EXP,IEP,ISO)
Prostatic Neoplasms  (EXP,IEP,ISO)
Rapp-Hodgkin syndrome  (ISO)
schizophrenia  (ISO)
Skin Abnormalities  (ISO)
split hand-foot malformation  (ISO)
split hand-foot malformation 4  (ISO)
squamous cell carcinoma  (ISO)
squamous cell neoplasm  (ISO)
Sweat Gland Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dibromoethane  (EXP)
1,2-dichloroethane  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-dichloroaniline  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-vinylcyclohexene dioxide  (EXP)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antimonite  (ISO)
antirheumatic drug  (ISO)
apigenin  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butan-1-ol  (ISO)
butane-2,3-dione  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloropicrin  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cycloheximide  (ISO)
diarsenic trioxide  (ISO)
dibenzo[a,l]pyrene  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
emodin  (EXP)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
ethylenediaminetetraacetic acid  (ISO)
eugenol  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
Fusarenone X  (EXP)
genistein  (ISO)
glycidol  (EXP)
graphite  (EXP)
hydroxyurea  (EXP)
isobutanol  (ISO)
kaempferol  (ISO)
ketoconazole  (EXP)
lactacystin  (ISO)
lead diacetate  (EXP)
leptomycin B  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
luteolin  (ISO)
melphalan  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
myricetin  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel dichloride  (ISO)
Octicizer  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
progesterone  (ISO)
quercetin  (ISO)
quercitrin  (ISO)
quinolin-8-ol  (EXP)
rac-lactic acid  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
anatomical structure formation involved in morphogenesis  (IMP)
animal organ morphogenesis  (IMP)
apoptotic process  (IMP,TAS)
cellular response to DNA damage stimulus  (ISO)
cellular senescence  (IMP)
chromatin remodeling  (IMP)
cloacal septation  (IMP)
cranial skeletal system development  (IMP)
developmental process  (IEA)
ectoderm and mesoderm interaction  (IMP)
embryonic forelimb morphogenesis  (IMP)
embryonic hindlimb morphogenesis  (IMP)
embryonic limb morphogenesis  (IGI,IMP)
epidermal cell differentiation  (IMP)
epidermal cell division  (IMP)
epidermis development  (IMP)
epithelial cell apoptotic process  (IMP)
epithelial cell development  (IMP)
epithelial cell differentiation  (IMP)
establishment of planar polarity  (IDA)
establishment of skin barrier  (IMP)
female genitalia morphogenesis  (IMP)
hair follicle development  (IMP)
hair follicle morphogenesis  (IMP)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  (IMP)
keratinocyte development  (IDA)
keratinocyte differentiation  (IDA,IGI)
keratinocyte proliferation  (IDA,IGI)
morphogenesis of a polarized epithelium  (IMP)
multicellular organism aging  (IMP)
negative regulation of cellular senescence  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of epithelial cell apoptotic process  (IMP)
negative regulation of intracellular estrogen receptor signaling pathway  (IMP)
negative regulation of keratinocyte differentiation  (IGI,IMP)
negative regulation of mesoderm development  (IMP)
negative regulation of transcription by RNA polymerase II  (IDA,IEP,IGI,IMP,ISO)
neuron apoptotic process  (IMP)
Notch signaling pathway  (IMP)
odontogenesis of dentin-containing tooth  (IMP)
pattern specification process  (IMP)
polarized epithelial cell differentiation  (IMP)
positive regulation of apoptotic signaling pathway  (IDA)
positive regulation of cell cycle G1/S phase transition  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of fibroblast apoptotic process  (ISO)
positive regulation of keratinocyte proliferation  (IGI)
positive regulation of mesenchymal cell proliferation  (IMP)
positive regulation of Notch signaling pathway  (IMP,ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of somatic stem cell population maintenance  (IMP)
positive regulation of stem cell proliferation  (IGI)
positive regulation of transcription by RNA polymerase II  (IDA,IEP,IMP,ISO)
post-anal tail morphogenesis  (IMP)
prostate gland development  (IMP)
prostatic bud formation  (IMP)
protein tetramerization  (IEA)
proximal/distal pattern formation  (IMP)
regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IMP)
regulation of DNA-templated transcription  (IEA)
regulation of epidermal cell division  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
skeletal system development  (IMP)
skin epidermis development  (IMP)
skin morphogenesis  (IMP)
smooth muscle tissue development  (IMP)
spermatogenesis  (ISO)
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development  (IMP)
stem cell differentiation  (IMP)
stem cell proliferation  (IDA,IGI,IMP)
sympathetic nervous system development  (IMP)
transcription by RNA polymerase II  (IDA,IMP)
urinary bladder development  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal abdominal wall morphology  (IAGP)
abnormal anus morphology  (IAGP)
abnormal apical ectodermal ridge morphology  (IAGP)
abnormal cellular replicative senescence  (IAGP)
abnormal corneal epithelium morphology  (IAGP)
abnormal craniofacial development  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal embryo development  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal epidermis stratum spinosum morphology  (IAGP)
abnormal esophageal epithelium morphology  (IAGP)
abnormal esophageal squamous epithelium morphology  (IAGP)
abnormal esophagus development  (IAGP)
abnormal eye morphology  (IAGP)
abnormal facial morphology  (IAGP)
abnormal female reproductive system morphology  (IAGP)
abnormal forelimb morphology  (IAGP)
abnormal hair follicle development  (IAGP)
abnormal hair shaft morphology  (IAGP)
abnormal horizontal basal cell of olfactory epithelium morphology  (IAGP)
abnormal humerus morphology  (IAGP)
abnormal keratinocyte differentiation  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal keratinocyte physiology  (IAGP)
abnormal limb bone morphology  (IAGP)
abnormal limb bud morphology  (IAGP)
abnormal limb development  (IAGP)
abnormal limb morphology  (IAGP)
abnormal mitochondrial physiology  (IAGP)
abnormal olfactory epithelium morphology  (IAGP)
abnormal olfactory gland morphology  (IAGP)
abnormal palatal shelf fusion at midline  (IAGP)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal periderm morphology  (IAGP)
abnormal phalanx morphology  (IAGP)
abnormal primitive urogenital sinus morphology  (IAGP)
abnormal prostate gland branching morphogenesis  (IAGP)
abnormal rectum morphology  (IAGP)
abnormal reproductive system morphology  (IAGP)
abnormal respiratory epithelium morphology  (IAGP)
abnormal secondary palate development  (IAGP)
abnormal septation of the cloaca  (IAGP)
abnormal skin condition  (IAGP)
abnormal skin development  (IAGP)
abnormal skin morphology  (IAGP)
abnormal skin physiology  (IAGP)
abnormal stomach epithelium morphology  (IAGP)
abnormal stomach non-glandular epithelium morphology  (IAGP)
abnormal tongue epithelium morphology  (IAGP)
abnormal tooth development  (IAGP)
abnormal tooth root morphology  (IAGP)
abnormal tracheal ciliated epithelium morphology  (IAGP)
abnormal urinary bladder detrusor smooth muscle morphology  (IAGP)
abnormal urinary bladder urothelium morphology  (IAGP)
abnormal uterine cervix epithelium morphology  (IAGP)
abnormal vagina epithelium morphology  (IAGP)
abnormal ventral body wall morphology  (IAGP)
absent apical ectodermal ridge  (IAGP)
absent carpal bone  (IAGP)
absent epidermis  (IAGP)
absent epidermis stratum corneum  (IAGP)
absent epidermis stratum granulosum  (IAGP)
absent epidermis stratum spinosum  (IAGP)
absent eyelids  (IAGP)
absent gastric milk in neonates  (IAGP)
absent hair follicles  (IAGP)
absent hindlimb  (IAGP)
absent lacrimal glands  (IAGP)
absent limbs  (IAGP)
absent mammary gland  (IAGP)
absent ovary  (IAGP)
absent oviduct  (IAGP)
absent prostate gland  (IAGP)
absent pubic symphysis  (IAGP)
absent radius  (IAGP)
absent salivary gland  (IAGP)
absent sebaceous gland  (IAGP)
absent teeth  (IAGP)
absent tongue squamous epithelium  (IAGP)
absent tooth placode  (IAGP)
absent ulna  (IAGP)
absent urinary bladder urothelium  (IAGP)
absent vibrissae  (IAGP)
acanthosis  (IAGP)
adactyly  (IAGP)
alopecia  (IAGP)
aneuploidy  (IAGP)
blistering  (IAGP)
chromosomal instability  (IAGP)
circling  (IAGP)
cleft palate  (IAGP)
clitoris hypoplasia  (IAGP)
decreased apoptosis  (IAGP)
decreased cell proliferation  (IAGP)
decreased cellular sensitivity to ionizing radiation  (IAGP)
decreased fetal size  (IAGP)
decreased hair follicle number  (IAGP)
decreased keratinocyte proliferation  (IAGP)
dehydration  (IAGP)
dermal-epidermal separation  (IAGP)
distended abdomen  (IAGP)
distended urinary bladder  (IAGP)
early cellular replicative senescence  (IAGP)
ectrodactyly  (IAGP)
embryonic lethality, incomplete penetrance  (IAGP)
enlarged lymph nodes  (IAGP)
esophagogastric junction metaplasia  (IAGP)
gastric cyst  (IAGP)
gastric metaplasia  (IAGP)
hemorrhage  (IAGP)
impaired skin barrier function  (IAGP)
impaired wound healing  (IAGP)
increased apoptosis  (IAGP)
increased carcinoma incidence  (IAGP)
increased chronic myelocytic leukemia incidence  (IAGP)
increased hemangiosarcoma incidence  (IAGP)
increased histiocytic sarcoma incidence  (IAGP)
increased lung adenocarcinoma incidence  (IAGP)
increased lung adenoma incidence  (IAGP)
increased malignant tumor incidence  (IAGP)
increased mammary adenocarcinoma incidence  (IAGP)
increased metastatic potential  (IAGP)
increased osteosarcoma incidence  (IAGP)
increased rhabdomyosarcoma incidence  (IAGP)
increased salivary gland adenoma incidence  (IAGP)
increased squamous cell carcinoma incidence  (IAGP)
increased susceptibility to infection  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased tumor incidence  (IAGP)
increased urinary bladder transitional cell carcinoma incidence  (IAGP)
intervertebral disk degeneration  (IAGP)
kidney cyst  (IAGP)
kidney inflammation  (IAGP)
kyphosis  (IAGP)
lordokyphosis  (IAGP)
monodactyly  (IAGP)
nail dystrophy  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
paralysis  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
premature aging  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IEA)
preweaning lethality, incomplete penetrance  (IAGP)
rectal prolapse  (IAGP)
rectovaginal fistula  (IAGP)
ruffled hair  (IAGP)
shiny skin  (IAGP)
short limbs  (IAGP)
skin lesions  (IAGP)
small limb buds  (IAGP)
small mandible  (IAGP)
small maxilla  (IAGP)
small tail bud  (IAGP)
small uterus  (IAGP)
spontaneous skin ulceration  (IAGP)
supernumerary teeth  (IAGP)
syndactyly  (IAGP)
thick dermal layer  (IAGP)
thick epidermis  (IAGP)
thick epidermis stratum basale  (IAGP)
thick epidermis stratum spinosum  (IAGP)
thin urinary bladder urothelium  (IAGP)
translucent skin  (IAGP)
umbilical hernia  (IAGP)
urinary bladder exstrophy  (IAGP)
uterine cervix inflammation  (IAGP)
weakness  (IAGP)
weight loss  (IAGP)
wrinkled skin  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. A novel c.1037C > G (p.Ala346Gly) mutation in TP63 as cause of the ectrodactyly-ectodermal dysplasia and cleft lip/palate (EEC) syndrome. Alves LU, etal., Genet Mol Biol. 2015 Mar;38(1):37-41. doi: 10.1590/S1415-475738120140125. Epub 2014 Mar 17.
2. Proliferation and apoptotic rates and increased frequency of p63-positive cells in the prostate acinar epithelium of alloxan-induced diabetic rats. Arcolino FO, etal., Int J Exp Pathol. 2010 Apr;91(2):144-54. doi: 10.1111/j.1365-2613.2009.00696.x. Epub 2009 Dec 22.
3. Analysis of the p63 gene in classical EEC syndrome, related syndromes, and non-syndromic orofacial clefts. Barrow LL, etal., J Med Genet. 2002 Aug;39(8):559-66.
4. Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome. Celli J, etal., Cell. 1999 Oct 15;99(2):143-53.
5. Molecular basis of EEC (ectrodactyly, ectodermal dysplasia, clefting) syndrome: five new mutations in the DNA-binding domain of the TP63 gene and genotype-phenotype correlation. Clements SE, etal., Br J Dermatol. 2010 Jan;162(1):201-7. doi: 10.1111/j.1365-2133.2009.09496.x. Epub 2009 Nov 9.
6. Clinical Variability in a Family with an Ectodermal Dysplasia Syndrome and a Nonsense Mutation in the TP63 Gene. Eisenkraft A, etal., Fetal Pediatr Pathol. 2015;34(6):400-6. doi: 10.3109/15513815.2015.1095261. Epub 2015 Oct 16.
7. Mutant p53: one name, many proteins. Freed-Pastor WA and Prives C, Genes Dev. 2012 Jun 15;26(12):1268-86. doi: 10.1101/gad.190678.112.
8. Impaired delta NP63 expression is associated with poor tumor development in transitional cell carcinoma of the bladder. He Y, etal., J Korean Med Sci. 2008 Oct;23(5):825-32.
9. Periacinar Clefting and p63 Immunostaining in Prostatic Intraepithelial Neoplasia and Prostatic Carcinoma. Kruslin B, etal., Pathol Oncol Res. 2006;12(4):205-9. Epub 2006 Dec 25.
10. DeltaNp63 protein expression in uterine cervical and endometrial cancers. Lin Z, etal., J Cancer Res Clin Oncol. 2006 Dec;132(12):811-6. Epub 2006 Jun 28.
11. DeltaNp63 expression is associated with poor survival in ovarian cancer. Marchini S, etal., Ann Oncol. 2008 Mar;19(3):501-7. Epub 2007 Nov 12.
12. Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. McGrath JA, etal., Hum Mol Genet. 2001 Feb 1;10(3):221-9.
13. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
14. MGDs mouse GO annotations MGD data from the GO Consortium
15. MGD IEA MGD IEA
16. The corneal epithelial stem cell. Moore JE, etal., DNA Cell Biol. 2002 May-Jun;21(5-6):443-51.
17. p53 mutations in cancer. Muller PA and Vousden KH, Nat Cell Biol. 2013 Jan;15(1):2-8. doi: 10.1038/ncb2641.
18. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
19. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
20. TP63 mutation and clefting modifier genes in an EEC syndrome family. Ray AK, etal., Clin Genet. 2004 Sep;66(3):217-22.
21. Progression of prostate cancer from a subset of p63-positive basal epithelial cells in FG/Tag transgenic mice. Reiner T, etal., Mol Cancer Res. 2007 Nov;5(11):1171-9. Epub 2007 Nov 2.
22. Mouse MP Annotation Import Pipeline RGD automated import pipeline
23. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
24. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
25. EEC (Ectrodactyly, Ectodermal dysplasia, Clefting) syndrome: heterozygous mutation in the p63 gene (R279H) and DNA-based prenatal diagnosis. South AP, etal., Br J Dermatol. 2002 Feb;146(2):216-20.
26. E-cadherin and p63 immunoexpression in dysplastic lesions and urothelial carcinomas of the bladder. Stepan A, etal., Rom J Morphol Embryol. 2009;50(3):461-5.
27. Anorectal malformation associated with a mutation in the P63 gene in a family with split hand-foot malformation. Su P, etal., Int J Colorectal Dis. 2013 Dec;28(12):1621-7. doi: 10.1007/s00384-013-1725-6. Epub 2013 Jun 5.
28. Diagnostic and prognostic impact of p63 immunoreactivity in renal malignancies. Tuna B, etal., Anal Quant Cytol Histol. 2009 Apr;31(2):118-22.
29. p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation. van Bokhoven H, etal., Am J Hum Genet. 2001 Sep;69(3):481-92. Epub 2001 Jul 17.
30. An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Vernersson Lindahl E, etal., Am J Med Genet A. 2013 Aug;161A(8):1961-71. doi: 10.1002/ajmg.a.36074. Epub 2013 Jun 14.
31. Integrating expression-related SNPs into genome-wide gene- and pathway-based analyses identified novel lung cancer susceptibility genes. Wang Y, etal., Int J Cancer. 2018 Apr 15;142(8):1602-1610. doi: 10.1002/ijc.31182. Epub 2017 Dec 12.
32. Analysis of large phenotypic variability of EEC and SHFM4 syndromes caused by K193E mutation of the TP63 gene. Wei J, etal., PLoS One. 2012;7(5):e35337. doi: 10.1371/journal.pone.0035337. Epub 2012 May 4.
33. Insertion/deletion polymorphisms in the DeltaNp63 promoter are a risk factor for bladder exstrophy epispadias complex. Wilkins S, etal., PLoS Genet. 2012;8(12):e1003070. doi: 10.1371/journal.pgen.1003070. Epub 2012 Dec 20.
34. TP63 gene mutations in Chinese P63 syndrome patients. Yin W, etal., J Dent Res. 2010 Aug;89(8):813-7. doi: 10.1177/0022034510366804. Epub 2010 Apr 21.
Additional References at PubMed
PMID:9315105   PMID:9703973   PMID:9774969   PMID:9799841   PMID:10203277   PMID:10227293   PMID:10227294   PMID:10231571   PMID:10349636   PMID:10657951   PMID:10754563   PMID:11042159  
PMID:11076861   PMID:11106548   PMID:11118893   PMID:11217851   PMID:11470269   PMID:11522642   PMID:11733180   PMID:11747081   PMID:11825686   PMID:11857801   PMID:11932750   PMID:12368184  
PMID:12368193   PMID:12477932   PMID:12702649   PMID:12789272   PMID:12941620   PMID:12951416   PMID:14526104   PMID:14555234   PMID:14729569   PMID:14757276   PMID:14998922   PMID:15033906  
PMID:15189821   PMID:15261144   PMID:15280445   PMID:15361520   PMID:15371305   PMID:15371309   PMID:15375216   PMID:15528198   PMID:15543231   PMID:15585950   PMID:15607981   PMID:15653949  
PMID:15659035   PMID:15716346   PMID:15746257   PMID:15797384   PMID:15837625   PMID:15908775   PMID:15922574   PMID:15982302   PMID:15987773   PMID:15988020   PMID:16007124   PMID:16007185  
PMID:16051706   PMID:16080917   PMID:16081516   PMID:16107615   PMID:16141072   PMID:16141073   PMID:16324689   PMID:16337913   PMID:16342117   PMID:16363065   PMID:16406339   PMID:16410075  
PMID:16466397   PMID:16524929   PMID:16557273   PMID:16601749   PMID:16601753   PMID:16602821   PMID:16618715   PMID:16618808   PMID:16645595   PMID:16714381   PMID:16715076   PMID:16914490  
PMID:16940753   PMID:16998800   PMID:17018588   PMID:17036050   PMID:17041601   PMID:17041603   PMID:17045206   PMID:17050669   PMID:17079275   PMID:17079460   PMID:17079689   PMID:17093266  
PMID:17122775   PMID:17159913   PMID:17164413   PMID:17182369   PMID:17198697   PMID:17224652   PMID:17276340   PMID:17317930   PMID:17360634   PMID:17383628   PMID:17482546   PMID:17522155  
PMID:17603506   PMID:17626181   PMID:17631878   PMID:17653081   PMID:17662267   PMID:17823311   PMID:17846227   PMID:17878916   PMID:18028901   PMID:18159078   PMID:18164684   PMID:18199584  
PMID:18256694   PMID:18275068   PMID:18287559   PMID:18289041   PMID:18292208   PMID:18292212   PMID:18311128   PMID:18326838   PMID:18353300   PMID:18374910   PMID:18410734   PMID:18483491  
PMID:18544451   PMID:18585372   PMID:18586087   PMID:18593557   PMID:18633439   PMID:18634775   PMID:18648642   PMID:18786355   PMID:18849344   PMID:18927586   PMID:18927616   PMID:19038788  
PMID:19092943   PMID:19235715   PMID:19300453   PMID:19303948   PMID:19345189   PMID:19371732   PMID:19403656   PMID:19439425   PMID:19458240   PMID:19461998   PMID:19494829   PMID:19502490  
PMID:19555433   PMID:19570515   PMID:19574443   PMID:19622632   PMID:19631635   PMID:19686689   PMID:19717565   PMID:19749746   PMID:19763140   PMID:19782673   PMID:19783996   PMID:19816568  
PMID:19876067   PMID:19898465   PMID:19946331   PMID:19956733   PMID:20038814   PMID:20043902   PMID:20059953   PMID:20090763   PMID:20105280   PMID:20157559   PMID:20157588   PMID:20161489  
PMID:20211142   PMID:20308292   PMID:20332116   PMID:20335364   PMID:20379195   PMID:20424325   PMID:20424327   PMID:20430747   PMID:20485546   PMID:20498273   PMID:20519941   PMID:20523354  
PMID:20559324   PMID:20658693   PMID:20697379   PMID:20930145   PMID:20962848   PMID:20962855   PMID:20975950   PMID:21042780   PMID:21068065   PMID:21093383   PMID:21098114   PMID:21114965  
PMID:21127199   PMID:21127502   PMID:21136383   PMID:21228373   PMID:21262812   PMID:21267068   PMID:21285247   PMID:21293190   PMID:21295273   PMID:21300779   PMID:21303954   PMID:21307095  
PMID:21309073   PMID:21335238   PMID:21356385   PMID:21402782   PMID:21429982   PMID:21435444   PMID:21438071   PMID:21505443   PMID:21531785   PMID:21558811   PMID:21576089   PMID:21624358  
PMID:21637289   PMID:21677159   PMID:21703447   PMID:21743007   PMID:21750033   PMID:21760596   PMID:21768372   PMID:21799872   PMID:21803035   PMID:21873635   PMID:21897369   PMID:21898690  
PMID:21905163   PMID:21909072   PMID:21912215   PMID:21926108   PMID:21930775   PMID:21965674   PMID:21982232   PMID:21982646   PMID:22027432   PMID:22038471   PMID:22113860   PMID:22117221  
PMID:22153372   PMID:22167068   PMID:22173065   PMID:22178326   PMID:22197488   PMID:22232434   PMID:22240899   PMID:22244744   PMID:22274697   PMID:22421361   PMID:22442009   PMID:22496369  
PMID:22508511   PMID:22560297   PMID:22573176   PMID:22575646   PMID:22662233   PMID:22714890   PMID:22763785   PMID:22922031   PMID:22935613   PMID:22949635   PMID:22949650   PMID:23000175  
PMID:23034632   PMID:23040072   PMID:23108156   PMID:23151848   PMID:23184966   PMID:23213461   PMID:23219093   PMID:23251530   PMID:23251711   PMID:23300485   PMID:23344544   PMID:23362346  
PMID:23396188   PMID:23406900   PMID:23449535   PMID:23481305   PMID:23516636   PMID:23553930   PMID:23589895   PMID:23598363   PMID:23608756   PMID:23614751   PMID:23620512   PMID:23686138  
PMID:23686616   PMID:23754280   PMID:23806336   PMID:23809701   PMID:23830984   PMID:23831572   PMID:23863842   PMID:23867503   PMID:23873029   PMID:23904595   PMID:23906066   PMID:23916850  
PMID:23924630   PMID:23924632   PMID:23974039   PMID:23993789   PMID:24013722   PMID:24038357   PMID:24068956   PMID:24075906   PMID:24127607   PMID:24134540   PMID:24145187   PMID:24146773  
PMID:24218621   PMID:24258200   PMID:24260306   PMID:24260555   PMID:24262428   PMID:24263106   PMID:24274029   PMID:24294373   PMID:24309930   PMID:24337118   PMID:24346698   PMID:24357321  
PMID:24360809   PMID:24412575   PMID:24415949   PMID:24440910   PMID:24449888   PMID:24478334   PMID:24482479   PMID:24503032   PMID:24515437   PMID:24569166   PMID:24590292   PMID:24594519  
PMID:24669837   PMID:24692510   PMID:24725274   PMID:24735878   PMID:24794706   PMID:24809925   PMID:24859845   PMID:24952961   PMID:24982158   PMID:24983500   PMID:24992712   PMID:25043473  
PMID:25043474   PMID:25091041   PMID:25100655   PMID:25133425   PMID:25146927   PMID:25163637   PMID:25166858   PMID:25168238   PMID:25168241   PMID:25190801   PMID:25191969   PMID:25210499  
PMID:25241036   PMID:25249461   PMID:25329657   PMID:25340052   PMID:25358290   PMID:25358791   PMID:25383540   PMID:25387952   PMID:25398052   PMID:25409149   PMID:25430793   PMID:25503409  
PMID:25516972   PMID:25523394   PMID:25564622   PMID:25567987   PMID:25601450   PMID:25603931   PMID:25655704   PMID:25668240   PMID:25704602   PMID:25739959   PMID:25790093   PMID:25790853  
PMID:25820239   PMID:25827072   PMID:25848986   PMID:25897018   PMID:25912685   PMID:25968320   PMID:26023097   PMID:26076167   PMID:26115514   PMID:26116174   PMID:26203562   PMID:26235047  
PMID:26305958   PMID:26329601   PMID:26359534   PMID:26371508   PMID:26538393   PMID:26555052   PMID:26566817   PMID:26652033   PMID:26685160   PMID:26690418   PMID:26711500   PMID:26742488  
PMID:26755636   PMID:26768665   PMID:26917450   PMID:26989131   PMID:27019188   PMID:27021569   PMID:27132513   PMID:27184845   PMID:27300436   PMID:27302476   PMID:27335464   PMID:27341756  
PMID:27511831   PMID:27654891   PMID:27709293   PMID:27716744   PMID:27721240   PMID:27725202   PMID:27770432   PMID:27807348   PMID:27869165   PMID:27889317   PMID:27910949   PMID:28028137  
PMID:28041841   PMID:28052057   PMID:28107452   PMID:28211873   PMID:28253399   PMID:28324176   PMID:28333962   PMID:28346423   PMID:28400434   PMID:28438836   PMID:28480888   PMID:28505376  
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PMID:29520104   PMID:29523849   PMID:29587145   PMID:29632206   PMID:29670083   PMID:29700203   PMID:29716728   PMID:29885760   PMID:29913133   PMID:29981310   PMID:29988075   PMID:30061411  
PMID:30153454   PMID:30189017   PMID:30220568   PMID:30305289   PMID:30366903   PMID:30390666   PMID:30478225   PMID:30651296   PMID:30696710   PMID:30701202   PMID:30714224   PMID:30720908  
PMID:30745430   PMID:30866939   PMID:30875130   PMID:30910837   PMID:30912742   PMID:30916783   PMID:30944105   PMID:31118233   PMID:31216312   PMID:31221639   PMID:31345929   PMID:31597917  
PMID:31624230   PMID:31631837   PMID:31636950   PMID:31712410   PMID:31776260   PMID:31794060   PMID:31813798   PMID:31875961   PMID:31943082   PMID:31949138   PMID:31953387   PMID:32081850  
PMID:32179912   PMID:32276991   PMID:32325033   PMID:32381741   PMID:32385093   PMID:32392534   PMID:32464196   PMID:32568216   PMID:32572167   PMID:32748407   PMID:32758484   PMID:32866472  
PMID:32878924   PMID:32932139   PMID:33025905   PMID:33056990   PMID:33141892   PMID:33144400   PMID:33159086   PMID:33318148   PMID:33328632   PMID:33428297   PMID:33452256   PMID:33469811  
PMID:33495473   PMID:33515576   PMID:33715275   PMID:33882290   PMID:33882306   PMID:33906607   PMID:33920782   PMID:34023861   PMID:34050161   PMID:34111600   PMID:34129836   PMID:34286693  
PMID:34302166   PMID:34315090   PMID:34445673   PMID:34590686   PMID:34789718   PMID:34998785   PMID:35020897   PMID:35077450   PMID:35103284   PMID:35103750   PMID:35112129   PMID:35283102  
PMID:35302059   PMID:35593401   PMID:35648290   PMID:35902588   PMID:35905011   PMID:36057966   PMID:36094016   PMID:36100434   PMID:36178196   PMID:36202783   PMID:36398878   PMID:36433959  


Genomics

Comparative Map Data
Trp63
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391625,502,513 - 25,710,838 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1625,502,513 - 25,710,852 (+)EnsemblGRCm39 Ensembl
GRCm381625,683,763 - 25,892,088 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1625,683,763 - 25,892,102 (+)EnsemblGRCm38mm10GRCm38
MGSCv371625,683,851 - 25,892,174 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361625,717,291 - 25,807,429 (+)NCBIMGSCv36mm8
Celera1626,227,614 - 26,435,704 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1617.37NCBI
TP63
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383189,596,746 - 189,897,276 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3189,631,389 - 189,897,276 (+)EnsemblGRCh38hg38GRCh38
GRCh373189,314,535 - 189,615,065 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363190,831,910 - 191,097,759 (+)NCBINCBI36Build 36hg18NCBI36
Celera3187,783,803 - 188,042,610 (+)NCBICelera
Cytogenetic Map3q28NCBI
HuRef3186,752,882 - 187,012,887 (+)NCBIHuRef
CHM1_13189,312,090 - 189,577,623 (+)NCBICHM1_1
T2T-CHM13v2.03192,413,470 - 192,713,713 (+)NCBIT2T-CHM13v2.0
Tp63
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21174,838,858 - 75,049,764 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,838,859 - 75,049,398 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1183,648,386 - 83,858,432 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01176,283,447 - 76,493,481 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01175,342,697 - 75,553,279 (-)NCBIRnor_WKY
Rnor_6.01178,234,853 - 78,456,559 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,234,800 - 78,456,501 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,262,234 - 82,484,354 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,900,622 - 77,200,251 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,958,211 - 77,257,840 (-)NCBI
Celera1173,744,494 - 73,953,104 (-)NCBICelera
Cytogenetic Map11q22NCBI
Tp63
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542018,176,155 - 18,384,786 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542018,178,639 - 18,384,786 (-)NCBIChiLan1.0ChiLan1.0
TP63
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13195,172,810 - 195,473,085 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3195,199,167 - 195,474,104 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03186,651,879 - 186,918,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
TP63
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13421,766,861 - 21,985,095 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3421,766,496 - 21,983,046 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3425,860,495 - 26,078,655 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03421,700,749 - 21,919,495 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3421,700,663 - 21,918,660 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13421,716,204 - 21,934,749 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03421,710,660 - 21,927,985 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03421,951,749 - 22,170,136 (+)NCBIUU_Cfam_GSD_1.0
Tp63
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602114,397,903 - 114,613,831 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936578491,507 - 705,729 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936578492,267 - 705,282 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TP63
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13127,116,105 - 127,347,068 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113127,115,990 - 127,347,082 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213136,309,804 - 136,515,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TP63
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11583,861,489 - 84,126,675 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604157,444,595 - 57,708,553 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tp63
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473067,286,160 - 67,489,670 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473067,283,444 - 67,489,808 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir92-1mmu-miR-92a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19608627
Mir92-2mmu-miR-92a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19608627
Mir203mmu-miR-203-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI18311128
Mir203mmu-miR-203-3pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI20216554

Predicted Target Of
Summary Value
Count of predictions:5110
Count of miRNA genes:794
Interacting mature miRNAs:1093
Transcripts:ENSMUST00000040231, ENSMUST00000065523, ENSMUST00000115304, ENSMUST00000115305, ENSMUST00000115306, ENSMUST00000115307, ENSMUST00000115308, ENSMUST00000115310
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128434358Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129674200Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130066977Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130814572Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16713690629225471Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
11565820Vasr1_mvariability in acoustic startle response 1 (mouse)161969865726368664Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
15092062Egrme4_mearly growth rate, maternal effect 4 (mouse)162521866444220250Mouse

Markers in Region
AI462811  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,891,676 - 25,891,759UniSTSGRCm38
MGSCv371625,891,762 - 25,891,845UniSTSGRCm37
Celera1626,435,292 - 26,435,375UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Whitehead/MRC_RH16220.27UniSTS
31.MMHAP58FLC4.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,784,079 - 25,784,278UniSTSGRCm38
MGSCv371625,784,165 - 25,784,364UniSTSGRCm37
Celera1626,327,938 - 26,328,137UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Whitehead_YAC16 UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371625,868,269 - 25,871,183UniSTSGRCm37
MGSCv371625,865,002 - 25,865,211UniSTSGRCm37
Celera1626,408,532 - 26,408,741UniSTS
Celera1626,411,799 - 26,414,713UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
cM Map1619.3UniSTS
cM Map1619.3UniSTS
cM Map1619.3UniSTS
AB010152  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,890,490 - 25,890,611UniSTSGRCm38
MGSCv371625,890,576 - 25,890,697UniSTSGRCm37
Celera1626,434,106 - 26,434,227UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Whitehead/MRC_RH16221.52UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381625,864,916 - 25,865,125UniSTSGRCm38
MGSCv371625,865,002 - 25,865,211UniSTSGRCm37
Celera1626,408,532 - 26,408,741UniSTS
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
cM Map1619.3UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS
Trp63  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16B1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001127259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001127265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006522002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB010152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC109213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC113020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF075439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF533892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC090649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC092537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000040231   ⟹   ENSMUSP00000038117
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,710,852 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,892,102 (+)Ensembl
RefSeq Acc Id: ENSMUST00000065523   ⟹   ENSMUSP00000067005
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,515 - 25,710,837 (+)Ensembl
GRCm38.p6 Ensembl1625,683,765 - 25,892,087 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115304   ⟹   ENSMUSP00000110959
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,686,604 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,867,854 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115305   ⟹   ENSMUSP00000110960
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,695,894 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,877,144 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115306   ⟹   ENSMUSP00000110961
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,620,666 - 25,710,852 (+)Ensembl
GRCm38.p6 Ensembl1625,801,916 - 25,892,102 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115307   ⟹   ENSMUSP00000110962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,513 - 25,640,068 (+)Ensembl
GRCm38.p6 Ensembl1625,683,763 - 25,821,318 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115308   ⟹   ENSMUSP00000110963
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,515 - 25,695,894 (+)Ensembl
GRCm38.p6 Ensembl1625,683,765 - 25,877,144 (+)Ensembl
RefSeq Acc Id: ENSMUST00000115310   ⟹   ENSMUSP00000110965
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1625,502,515 - 25,710,852 (+)Ensembl
GRCm38.p6 Ensembl1625,683,765 - 25,892,102 (+)Ensembl
RefSeq Acc Id: NM_001127259   ⟹   NP_001120731
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,515 - 25,710,838 (+)NCBI
GRCm381625,683,765 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127260   ⟹   NP_001120732
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,515 - 25,710,838 (+)NCBI
GRCm381625,683,765 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127261   ⟹   NP_001120733
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,515 - 25,695,894 (+)NCBI
GRCm381625,683,765 - 25,877,144 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127262   ⟹   NP_001120734
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,710,838 (+)NCBI
GRCm381625,801,916 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127263   ⟹   NP_001120735
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,695,894 (+)NCBI
GRCm381625,801,916 - 25,877,144 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127264   ⟹   NP_001120736
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,710,838 (+)NCBI
GRCm381625,801,916 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001127265   ⟹   NP_001120737
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,695,894 (+)NCBI
GRCm381625,801,916 - 25,877,144 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_011641   ⟹   NP_035771
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,666 - 25,710,838 (+)NCBI
GRCm381625,801,916 - 25,892,088 (+)NCBI
MGSCv371625,683,851 - 25,892,174 (+)RGD
Celera1626,227,614 - 26,435,704 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006522000   ⟹   XP_006522063
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,513 - 25,710,030 (+)NCBI
GRCm381625,683,763 - 25,889,339 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522001   ⟹   XP_006522064
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,620,513 - 25,708,089 (+)NCBI
GRCm381625,801,763 - 25,889,339 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006522002   ⟹   XP_006522065
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391625,502,513 - 25,696,648 (+)NCBI
GRCm381625,683,763 - 25,877,898 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001120731 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120732 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120733 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120734 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120735 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120736 (Get FASTA)   NCBI Sequence Viewer  
  NP_001120737 (Get FASTA)   NCBI Sequence Viewer  
  NP_035771 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522063 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522064 (Get FASTA)   NCBI Sequence Viewer  
  XP_006522065 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC62639 (Get FASTA)   NCBI Sequence Viewer  
  AAC62640 (Get FASTA)   NCBI Sequence Viewer  
  AAC62641 (Get FASTA)   NCBI Sequence Viewer  
  AAC62642 (Get FASTA)   NCBI Sequence Viewer  
  AAC62643 (Get FASTA)   NCBI Sequence Viewer  
  AAC62644 (Get FASTA)   NCBI Sequence Viewer  
  AAH90649 (Get FASTA)   NCBI Sequence Viewer  
  AAH92537 (Get FASTA)   NCBI Sequence Viewer  
  AAP87982 (Get FASTA)   NCBI Sequence Viewer  
  AAP87983 (Get FASTA)   NCBI Sequence Viewer  
  AAP87984 (Get FASTA)   NCBI Sequence Viewer  
  AAP87985 (Get FASTA)   NCBI Sequence Viewer  
  AAP87986 (Get FASTA)   NCBI Sequence Viewer  
  AAP87987 (Get FASTA)   NCBI Sequence Viewer  
  BAA32432 (Get FASTA)   NCBI Sequence Viewer  
  BAC33397 (Get FASTA)   NCBI Sequence Viewer  
  BAE23286 (Get FASTA)   NCBI Sequence Viewer  
  EDK97682 (Get FASTA)   NCBI Sequence Viewer  
  EDK97683 (Get FASTA)   NCBI Sequence Viewer  
  EDK97684 (Get FASTA)   NCBI Sequence Viewer  
  O88898 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_035771   ⟸   NM_011641
- Peptide Label: isoform d
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL),   A0A6P5RCV0 (UniProtKB/TrEMBL),   A0A8C6GR94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120731   ⟸   NM_001127259
- Peptide Label: isoform a
- UniProtKB: Q9QWZ0 (UniProtKB/Swiss-Prot),   O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL),   A0A6P5R6S4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120732   ⟸   NM_001127260
- Peptide Label: isoform b
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL),   A0A6P5R7A3 (UniProtKB/TrEMBL),   A0A8C6GS08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120733   ⟸   NM_001127261
- Peptide Label: isoform c
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q569E5 (UniProtKB/TrEMBL),   A0A6P5R0F8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120734   ⟸   NM_001127262
- Peptide Label: isoform f
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q5CZX0 (UniProtKB/TrEMBL),   A0A6P5RCV3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120736   ⟸   NM_001127264
- Peptide Label: isoform e
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q3UVI3 (UniProtKB/TrEMBL),   Q5CZX0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120735   ⟸   NM_001127263
- Peptide Label: isoform g
- UniProtKB: Q569E5 (UniProtKB/TrEMBL),   A0A6P5R6T5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001120737   ⟸   NM_001127265
- Peptide Label: isoform h
- UniProtKB: O88898 (UniProtKB/Swiss-Prot),   Q569E5 (UniProtKB/TrEMBL),   A0A6P5R0G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522063   ⟸   XM_006522000
- Peptide Label: isoform X1
- UniProtKB: A0A6P5R0F4 (UniProtKB/TrEMBL),   A0A8C6GRK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522065   ⟸   XM_006522002
- Peptide Label: isoform X3
- UniProtKB: A0A6P5R6T0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006522064   ⟸   XM_006522001
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000067005   ⟸   ENSMUST00000065523
RefSeq Acc Id: ENSMUSP00000038117   ⟸   ENSMUST00000040231
RefSeq Acc Id: ENSMUSP00000110959   ⟸   ENSMUST00000115304
RefSeq Acc Id: ENSMUSP00000110962   ⟸   ENSMUST00000115307
RefSeq Acc Id: ENSMUSP00000110963   ⟸   ENSMUST00000115308
RefSeq Acc Id: ENSMUSP00000110960   ⟸   ENSMUST00000115305
RefSeq Acc Id: ENSMUSP00000110961   ⟸   ENSMUST00000115306
RefSeq Acc Id: ENSMUSP00000110965   ⟸   ENSMUST00000115310
Protein Domains
P53   P53_tetramer   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O88898-F1-model_v2 AlphaFold O88898 1-680 view protein structure

Promoters
RGD ID:8685876
Promoter ID:EPDNEW_M20969
Type:single initiation site
Name:Trp63_3
Description:Mus musculus transformation related protein 63 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20970  EPDNEW_M20971  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381625,683,763 - 25,683,823EPDNEW
RGD ID:8685878
Promoter ID:EPDNEW_M20970
Type:multiple initiation site
Name:Trp63_1
Description:Mus musculus transformation related protein 63 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20969  EPDNEW_M20971  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381625,801,916 - 25,801,976EPDNEW
RGD ID:8685880
Promoter ID:EPDNEW_M20971
Type:single initiation site
Name:Trp63_2
Description:Mus musculus transformation related protein 63 , transcript variant8, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M20969  EPDNEW_M20970  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381625,865,701 - 25,865,761EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1330810 AgrOrtholog
Ensembl Genes ENSMUSG00000022510 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000038117 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000067005 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110959.2 UniProtKB/TrEMBL
  ENSMUSP00000110960 ENTREZGENE
  ENSMUSP00000110960.2 UniProtKB/TrEMBL
  ENSMUSP00000110961 ENTREZGENE
  ENSMUSP00000110961.2 UniProtKB/TrEMBL
  ENSMUSP00000110962.2 UniProtKB/TrEMBL
  ENSMUSP00000110963 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000110965 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000040231 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000065523 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000115304.8 UniProtKB/TrEMBL
  ENSMUST00000115305 ENTREZGENE
  ENSMUST00000115305.2 UniProtKB/TrEMBL
  ENSMUST00000115306 ENTREZGENE
  ENSMUST00000115306.8 UniProtKB/TrEMBL
  ENSMUST00000115307.8 UniProtKB/TrEMBL
  ENSMUST00000115308 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000115310 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53/RUNT-type_TF_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_tetramer_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_tetrameristn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53_tumour_suppressor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tp63 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumor-p63_SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22061 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1330810 ENTREZGENE
NCBI Gene 22061 ENTREZGENE
PANTHER PTHR11447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11447:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam P53 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P53_tetramer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trp63 PhenoGen
PRINTS P53SUPPRESSR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE P53 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47719 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J1K8_MOUSE UniProtKB/TrEMBL
  A0A6P5R0F4 ENTREZGENE
  A0A6P5R0F8 ENTREZGENE
  A0A6P5R0G2 ENTREZGENE
  A0A6P5R6S4 ENTREZGENE
  A0A6P5R6T0 ENTREZGENE
  A0A6P5R6T5 ENTREZGENE
  A0A6P5R7A3 ENTREZGENE
  A0A6P5RCV0 ENTREZGENE
  A0A6P5RCV3 ENTREZGENE
  A0A8C6GR94 ENTREZGENE
  A0A8C6GRK8 ENTREZGENE
  A0A8C6GS08 ENTREZGENE
  D3Z7K2_MOUSE UniProtKB/TrEMBL
  O88898 ENTREZGENE, UniProtKB/Swiss-Prot
  Q3UVI3 ENTREZGENE, UniProtKB/TrEMBL
  Q569E5 ENTREZGENE, UniProtKB/TrEMBL
  Q5CZX0 ENTREZGENE, UniProtKB/TrEMBL
  Q9QWZ0 ENTREZGENE
UniProt Secondary O88897 UniProtKB/Swiss-Prot
  O88899 UniProtKB/Swiss-Prot
  O89097 UniProtKB/Swiss-Prot
  Q8C826 UniProtKB/Swiss-Prot
  Q9QWY9 UniProtKB/Swiss-Prot
  Q9QWZ0 UniProtKB/Swiss-Prot