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Gene: Dnase1l3 (deoxyribonuclease 1-like 3) Mus musculus
Symbol: Dnase1l3
Name: deoxyribonuclease 1-like 3
Description: Exhibits endonuclease activity. Involved in several processes, including apoptotic DNA fragmentation; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Localizes to nucleus. Orthologous to human DNASE1L3 (deoxyribonuclease 1 like 3); INTERACTS WITH 4,4'-diaminodiphenylmethane; buta-1,3-diene; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deoxyribonuclease gamma; deoxyribonuclease I-like 3; Dhp2; DNase gamma; DNase I homolog protein DHP2; DNase I-like 3; DNasegamma; liver and spleen DNase; LS-DNase; Lsd; macrophage specific DNase I
Homo sapiens (human) : DNASE1L3 (deoxyribonuclease 1 like 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dnase1l3 (deoxyribonuclease 1-like 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnase1l3 (deoxyribonuclease 1 like 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DNASE1L3 (deoxyribonuclease 1 like 3)
Canis lupus familiaris (dog) : DNASE1L3 (deoxyribonuclease 1 like 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnase1l3 (deoxyribonuclease 1 like 3)
Sus scrofa (pig) : DNASE1L3 (deoxyribonuclease 1 like 3)
Chlorocebus sabaeus (African green monkey) : DNASE1L3 (deoxyribonuclease 1 like 3)
Heterocephalus glaber (naked mole-rat) : Dnase1l3 (deoxyribonuclease 1 like 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl147,964,533 - 7,994,573 (-)EnsemblGRCm38mm10GRCm38
GRCm38147,965,187 - 7,994,760 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37148,797,701 - 8,826,696 (-)NCBIGRCm37mm9NCBIm37
MGSCv36146,757,066 - 6,786,061 (-)NCBImm8
Celera143,588,560 - 3,617,542 (-)NCBICelera
Cytogenetic Map14A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dnase1l3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733866
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-07-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.