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Gene: Pnpla6 (patatin-like phospholipase domain containing 6) Mus musculus
Symbol: Pnpla6
Name: patatin-like phospholipase domain containing 6
Description: Exhibits lysophospholipase activity. Involved in angiogenesis and animal organ morphogenesis. Localizes to membrane. Is expressed in several structures, including brain; cranial nerve; epithelium; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in Boucher-Neuhauser syndrome; Laurence-Moon syndrome; Oliver-McFarlane syndrome; and hereditary spastic paraplegia 39. Orthologous to human PNPLA6 (patatin like phospholipase domain containing 6); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,5,6-trichloro-2-pyridinol; 3,5,6-trichloropyridine-2-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI661849; MSws; neuropathy target esterase; Nte; patatin-like phospholipase domain-containing protein 6; Swiss cheese; Swiss-cheese
Homo sapiens (human) : PNPLA6 (patatin like phospholipase domain containing 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pnpla6 (patatin-like phospholipase domain containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pnpla6 (patatin like phospholipase domain containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PNPLA6 (patatin like phospholipase domain containing 6)
Canis lupus familiaris (dog) : PNPLA6 (patatin like phospholipase domain containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pnpla6 (patatin like phospholipase domain containing 6)
Sus scrofa (pig) : PNPLA6 (patatin like phospholipase domain containing 6)
Chlorocebus sabaeus (African green monkey) : PNPLA6 (patatin like phospholipase domain containing 6)
Heterocephalus glaber (naked mole-rat) : Pnpla6 (patatin like phospholipase domain containing 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl83,515,384 - 3,544,267 (+)EnsemblGRCm38mm10GRCm38
GRCm3883,515,235 - 3,544,267 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3783,515,384 - 3,544,267 (+)NCBIGRCm37mm9NCBIm37
MGSCv3683,515,384 - 3,544,267 (+)NCBImm8
Celera83,741,358 - 3,770,284 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map81.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pnpla6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1558075
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.