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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CERS6 protein affects the expression of ABCB1 protein] |
CTD |
PMID:26593909 PMID:34915026 |
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NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCG2 |
ATP binding cassette subfamily G member 2 (JR blood group) |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA] |
CTD |
PMID:17077187 |
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NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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G |
ACAA2 |
acetyl-CoA acyltransferase 2 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
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G |
ACE |
angiotensin I converting enzyme |
multiple interactions |
EXP |
[Butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of ACE protein mutant form; [Butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased activity of ACE protein mutant form |
CTD |
PMID:20454656 |
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NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
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G |
ACE2 |
angiotensin converting enzyme 2 |
multiple interactions decreases expression |
EXP |
ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]; ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein] |
CTD |
PMID:27638906 |
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NCBI chr X:15,518,197...15,607,211
Ensembl chr X:15,494,566...15,607,236
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G |
ACHE |
acetylcholinesterase (Yt blood group) |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein] |
CTD |
PMID:22944069 |
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NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
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G |
ACTA2 |
actin alpha 2, smooth muscle |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTA2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
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G |
ACTB |
actin beta |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTB mRNA |
CTD |
PMID:15857753 |
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NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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G |
ACTC1 |
actin alpha cardiac muscle 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589
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G |
ADAM17 |
ADAM metallopeptidase domain 17 |
multiple interactions increases expression |
EXP |
4-methylumbelliferone 8-carbaldehyde inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ADAM17 protein]; 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ADAM17 protein] |
CTD |
PMID:27638906 |
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NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
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G |
ADSS1 |
adenylosuccinate synthase 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSS1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSS1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr14:104,724,229...104,747,325
Ensembl chr14:104,724,174...104,747,325
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G |
AGRP |
agouti related neuropeptide |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AGRP mRNA |
CTD |
PMID:20061341 |
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NCBI chr16:67,482,571...67,483,547
Ensembl chr16:67,482,571...67,483,547
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G |
AGT |
angiotensinogen |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] |
CTD |
PMID:18487452 PMID:26612707 |
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NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AHR |
aryl hydrocarbon receptor |
multiple interactions increases expression increases localization affects localization decreases expression |
EXP ISO |
AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [beta-hexachlorocyclohexane affects the expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-formylindolo(3,2-b)carbazole results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AHR protein results in decreased expression of VIM protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [AHR protein results in increased expression of ESR1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [herbimycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [monorden results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and affects the localization of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [AHR protein binds to VIM protein] MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of AHR protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and affects the localization of AHR protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of AHR protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of AHR protein |
CTD RGD |
PMID:10497241 PMID:10722677 PMID:10922479 PMID:12002481 PMID:12237327 PMID:12606767 PMID:15385644 PMID:15899923 PMID:16891617 PMID:17445780 PMID:20057149 PMID:27752740 PMID:31676321 PMID:33207735 PMID:34801851 PMID:37217010 PMID:22079846 More...
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RGD:401794136 |
NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
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G |
AKR1B1 |
aldo-keto reductase family 1 member B |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B1 mRNA |
CTD |
PMID:21215737 |
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NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
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G |
AKR1B10 |
aldo-keto reductase family 1 member B10 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B10 mRNA |
CTD |
PMID:21215737 |
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NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
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G |
AKR1C1 |
aldo-keto reductase family 1 member C1 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Salicylic Acid inhibits the reaction [AKR1C1 protein results in decreased susceptibility to Cisplatin]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C1 mRNA |
CTD |
PMID:21215737 PMID:23165153 |
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NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
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G |
AKR1C3 |
aldo-keto reductase family 1 member C3 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C3 mRNA |
CTD |
PMID:21215737 PMID:23165153 |
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NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
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G |
AKT1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased phosphorylation of AKT1 protein] AKT1 protein modified form inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with dihydromyricetin] results in increased ubiquitination of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [sodium arsenite affects the expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tubocapsenolide A results in increased degradation of AKT1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of AKT1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKT1 protein |
CTD |
PMID:18442981 PMID:24085292 PMID:24449419 PMID:24933620 PMID:32061799 PMID:33256086 PMID:36807944 More...
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NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
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G |
ANLN |
anillin, actin binding protein |
decreases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ANLN mRNA |
CTD |
PMID:25566086 PMID:31806706 |
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NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791
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G |
ANXA2 |
annexin A2 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ANXA2 mRNA |
CTD |
PMID:31806706 |
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NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
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G |
AOC3 |
amine oxidase copper containing 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of AOC3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130
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G |
APH1A |
aph-1 homolog A, gamma-secretase subunit |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:150,265,404...150,269,016
Ensembl chr 1:150,265,399...150,269,580
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G |
APP |
amyloid beta precursor protein |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] |
CTD |
PMID:21520056 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
APPL1 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resiquimod results in increased degradation of APPL1 protein] |
CTD |
PMID:25780039 |
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NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105
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G |
AQP2 |
aquaporin 2 |
decreases degradation |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of AQP2 protein |
CTD |
PMID:21734099 |
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NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
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G |
AQP3 |
aquaporin 3 (Gill blood group) |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]] |
CTD |
PMID:23545307 |
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NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
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G |
AQP5 |
aquaporin 5 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]] |
CTD |
PMID:23545307 |
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NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682
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G |
AR |
androgen receptor |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [decursin results in increased degradation of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isobavachin results in decreased expression of and results in increased degradation of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulforaphane results in decreased expression of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Testosterone results in increased expression of AR mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of AR protein] |
CTD |
PMID:12376534 PMID:17723170 PMID:19805354 PMID:24740322 PMID:37019376 |
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NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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G |
ARG1 |
arginase 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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G |
ARIH1 |
ariadne RBR E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein] |
CTD |
PMID:25624349 |
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NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
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G |
ARL6IP5 |
ADP ribosylation factor like GTPase 6 interacting protein 5 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]] |
CTD |
PMID:21600884 |
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NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092
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G |
ARNT |
aryl hydrocarbon receptor nuclear translocator |
increases expression multiple interactions decreases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARNT mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in increased degradation of ARNT protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARNT protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [SP1 protein binds to ARNT promoter]; bisindolylmaleimide I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARNT mRNA] |
CTD |
PMID:14529614 PMID:15899923 PMID:16880289 |
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NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
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G |
ART3 |
ADP-ribosyltransferase 3 (inactive) |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 4:76,011,190...76,112,786
Ensembl chr 4:76,011,184...76,114,048
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G |
ASB2 |
ankyrin repeat and SOCS box containing 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ASB2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr14:93,934,166...93,976,570
Ensembl chr14:93,934,166...93,976,739
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G |
ATF3 |
activating transcription factor 3 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein] |
CTD |
PMID:23593480 |
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NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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G |
ATF4 |
activating transcription factor 4 |
increases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein] |
CTD |
PMID:14604972 PMID:17912641 PMID:23593480 PMID:31806706 |
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
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G |
ATF6 |
activating transcription factor 6 |
multiple interactions increases expression |
EXP |
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF6 protein]; ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]; ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein] |
CTD |
PMID:27638906 |
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NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
ATG12 |
autophagy related 12 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
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G |
ATG13 |
autophagy related 13 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] |
CTD |
PMID:27629431 |
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NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818
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G |
ATG7 |
autophagy related 7 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] |
CTD |
PMID:27629431 |
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NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
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G |
ATP13A2 |
ATPase cation transporting 13A2 |
decreases response to substance |
EXP |
ATP13A2 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde analog |
CTD |
PMID:22847264 |
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NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein] |
CTD |
PMID:10506578 |
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NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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G |
ATP5F1B |
ATP synthase F1 subunit beta |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of ATP5F1B mRNA] |
CTD |
PMID:20860658 |
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NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
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G |
ATP7B |
ATPase copper transporting beta |
decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of ATP7B protein |
CTD |
PMID:21189263 |
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NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
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G |
AURKA |
aurora kinase A |
multiple interactions |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased expression of and results in increased phosphorylation of AURKA protein; MLN8054 inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKA protein] |
CTD |
PMID:24976383 |
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NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
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G |
AURKB |
aurora kinase B |
multiple interactions |
EXP |
4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein |
CTD |
PMID:24976383 |
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NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
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G |
BACH1 |
BTB domain and CNC homolog 1 |
multiple interactions increases expression increases ubiquitination |
EXP |
2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] affects the localization of BACH1 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of BACH1 protein; [Hemin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of BACH1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tetrachlorobenzoquinone results in increased degradation of BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; quinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BACH1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BACH1 protein |
CTD |
PMID:27393035 PMID:28645578 PMID:33434570 |
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NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751
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G |
BAG3 |
BAG cochaperone 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Staurosporine results in increased degradation of BAG3 protein] |
CTD |
PMID:19352495 |
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NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
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G |
BAK1 |
BCL2 antagonist/killer 1 |
increases ubiquitination |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BAK1 protein |
CTD |
PMID:36346691 |
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NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of BAX protein MitoTEMPO inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BAX protein] |
CTD |
PMID:15782132 PMID:19540902 PMID:34418242 |
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BBC3 |
BCL2 binding component 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] |
CTD |
PMID:20530418 |
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NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
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G |
BCAS2 |
BCAS2 pre-mRNA processing factor |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCAS2 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 1:114,567,557...114,581,615
Ensembl chr 1:114,567,557...114,581,629
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G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [evodiamine results in increased cleavage of BCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [trimethyltin chloride results in decreased expression of BCL2 protein] benzyloxycarbonyl-valyl-alanyl-aspartic acid promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein]; MitoTEMPO inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein |
CTD |
PMID:19540902 PMID:20005289 PMID:20100472 PMID:20449726 PMID:23423712 PMID:34418242 More...
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2L1 |
BCL2 like 1 |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2L1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BCL2L1 protein] |
CTD |
PMID:16960866 PMID:19540902 PMID:19812371 |
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NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
BCL2L11 |
BCL2 like 11 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased degradation of BCL2L11 protein] |
CTD |
PMID:36509116 |
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NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
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G |
BIRC2 |
baculoviral IAP repeat containing 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC2 protein results in increased degradation of SOD1 protein mutant form] |
CTD |
PMID:27773815 |
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NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
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G |
BIRC3 |
baculoviral IAP repeat containing 3 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC3 protein results in increased degradation of SOD1 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC3 protein |
CTD |
PMID:14527959 PMID:24085292 PMID:27773815 |
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NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
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G |
BIRC5 |
baculoviral IAP repeat containing 5 |
increases expression multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC5 protein [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with dihydromyricetin] results in increased ubiquitination of BIRC5 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with MK 2206] results in increased ubiquitination of BIRC5 protein; AKT1 protein modified form inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with dihydromyricetin] results in increased ubiquitination of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [dihydromyricetin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to [Oxaliplatin results in decreased expression of BIRC5 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BIRC5 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BIRC5 protein] |
CTD |
PMID:16328441 PMID:17510429 PMID:17548900 PMID:19812371 PMID:19939880 PMID:20708607 PMID:23872705 PMID:25566086 PMID:36807944 More...
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NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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G |
BLVRB |
biliverdin reductase B |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BLVRB mRNA |
CTD |
PMID:25566086 |
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NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
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G |
BMI1 |
BMI1 proto-oncogene, polycomb ring finger |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BMI1 protein |
CTD |
PMID:33157086 |
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NCBI chr10:22,321,099...22,331,484
Ensembl chr10:22,321,099...22,331,484
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G |
BNIP3 |
BCL2 interacting protein 3 |
multiple interactions increases expression |
EXP |
[arsenic trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of BNIP3 mRNA; arsenic trioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BNIP3 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Valproic Acid results in increased expression of BNIP3 mRNA] |
CTD |
PMID:25446377 |
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NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
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G |
BOK |
BCL2 family apoptosis regulator BOK |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of BOK mRNA |
CTD |
PMID:25566086 |
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NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,424...241,574,131
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G |
BRD4 |
bromodomain containing 4 |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]] |
CTD |
PMID:23686307 PMID:25877301 PMID:26051217 |
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NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545
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G |
C1QB |
complement C1q B chain |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of C1QB mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
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G |
CA14 |
carbonic anhydrase 14 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078
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G |
CACNA1H |
calcium voltage-gated channel subunit alpha1 H |
decreases expression decreases degradation |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CACNA1H mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CACNA1H protein |
CTD |
PMID:25566086 PMID:30552955 |
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NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
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G |
CANX |
calnexin |
affects localization |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of CANX protein |
CTD |
PMID:17912641 |
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NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
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G |
CAPN1 |
calpain 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in increased expression of CAPN1 protein] |
CTD |
PMID:37353096 |
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NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
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G |
CASP1 |
caspase 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]] |
CTD |
PMID:15914627 |
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NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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G |
CASP3 |
caspase 3 |
multiple interactions increases cleavage increases expression increases activity |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CASP3 protein]; [Arsenic Trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased cleavage of CASP3 protein; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [evodiamine results in increased activity of and results in increased cleavage of CASP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP3 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CASP3 protein modified form benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein] |
CTD |
PMID:15498850 PMID:15725397 PMID:16880202 PMID:18463101 PMID:18790767 PMID:20005289 PMID:20100472 PMID:20449726 PMID:20649845 PMID:23684743 PMID:25449439 PMID:25568320 PMID:27638906 PMID:29944914 PMID:34418242 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP6 |
caspase 6 |
multiple interactions decreases activity |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of CASP6 protein |
CTD |
PMID:15914627 |
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NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
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G |
CASP7 |
caspase 7 |
increases activity |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP7 protein |
CTD |
PMID:19139269 |
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NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
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G |
CASP8 |
caspase 8 |
multiple interactions increases activity |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP8 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP8 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]] |
CTD |
PMID:15498850 PMID:15914627 PMID:20100472 PMID:20449726 PMID:20671745 |
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NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
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G |
CASP9 |
caspase 9 |
multiple interactions increases activity |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP9 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP9 protein |
CTD |
PMID:15498850 PMID:16880202 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAST |
calpastatin |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in increased cleavage of CAST protein] |
CTD |
PMID:37353096 |
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NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595 Ensembl chr 5:96,525,267...96,779,595
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G |
CAT |
catalase |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CAT mRNA CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein] |
CTD |
PMID:20061341 PMID:24973648 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CAV1 |
caveolin 1 |
decreases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAV1 protein [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CAV1 mRNA |
CTD |
PMID:19706615 PMID:25566086 |
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NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
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G |
CAVIN1 |
caveolae associated protein 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr17:42,402,449...42,423,256
Ensembl chr17:42,402,449...42,423,256
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G |
CAVIN2 |
caveolae associated protein 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 2:191,834,310...191,847,088
Ensembl chr 2:191,834,310...191,847,088
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G |
CBR3 |
carbonyl reductase 3 |
increases expression |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein] which results in increased expression of CBR3 mRNA |
CTD |
PMID:20806931 |
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NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of CCL2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA] |
CTD |
PMID:10541287 PMID:11230753 PMID:11698246 PMID:15139008 PMID:19945525 |
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NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL23 |
C-C motif chemokine ligand 23 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCL9 mRNA |
CTD |
PMID:25566086 |
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NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972
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G |
CCNA2 |
cyclin A2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNA2 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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G |
CCNB1 |
cyclin B1 |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [arsenite results in increased ubiquitination of CCNB1 protein] [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB1 mRNA |
CTD |
PMID:17373649 PMID:20061341 PMID:25566086 |
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NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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G |
CCNB2 |
cyclin B2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB2 mRNA |
CTD |
PMID:20061341 |
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NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
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G |
CCND1 |
cyclin D1 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3,3'-diindolylmethane analog results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alopestatin metabolite results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of CCND1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lysocellin results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased phosphorylation of CCND1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CCND1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased degradation of CCND1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein] |
CTD |
PMID:15247282 PMID:16051428 PMID:16525630 PMID:16707792 PMID:16965676 PMID:18792914 PMID:20394812 PMID:21472727 PMID:24231000 PMID:27424123 PMID:28548306 PMID:30703377 More...
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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CCND3 |
cyclin D3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCND3 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
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G |
CCS |
copper chaperone for superoxide dismutase |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein] |
CTD |
PMID:12832419 |
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NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
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G |
CD14 |
CD14 molecule |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
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CD1D |
CD1d molecule |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD1D1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427
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G |
CD248 |
CD248 molecule |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CD248 mRNA |
CTD |
PMID:25566086 |
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NCBI chr11:66,314,494...66,317,044
Ensembl chr11:66,314,494...66,317,044
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G |
CD36 |
CD36 molecule (CD36 blood group) |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD36 protein] |
CTD |
PMID:36534932 |
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NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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G |
CDC20 |
cell division cycle 20 |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of CDC20 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC20 mRNA |
CTD |
PMID:20054826 PMID:20061341 PMID:25566086 |
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NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
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G |
CDC25B |
cell division cycle 25B |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC25B mRNA |
CTD |
PMID:20061341 |
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NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
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G |
CDC25C |
cell division cycle 25C |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC25C mRNA |
CTD |
PMID:20061341 |
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NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
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G |
CDCA3 |
cell division cycle associated 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDCA3 mRNA |
CTD |
PMID:20061341 |
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NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
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G |
CDH3 |
cadherin 3 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDH3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:68,645,310...68,733,771
Ensembl chr16:68,636,189...68,727,468
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G |
CDK1 |
cyclin dependent kinase 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDK1 mRNA [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDK1 mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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G |
CDK2 |
cyclin dependent kinase 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of CDK2 protein] |
CTD |
PMID:15610522 |
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NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
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G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CDKN1B protein |
CTD |
PMID:17283133 |
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NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2A mRNA |
CTD |
PMID:20061341 |
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NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
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G |
CDKN2C |
cyclin dependent kinase inhibitor 2C |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2C mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:50,968,706...50,974,634
Ensembl chr 1:50,960,745...50,974,634
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G |
CDKN3 |
cyclin dependent kinase inhibitor 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN3 mRNA |
CTD |
PMID:20061341 |
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NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218
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G |
CEBPA |
CCAAT enhancer binding protein alpha |
increases ubiquitination multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of CEBPA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of CEBPA protein] |
CTD |
PMID:19662097 |
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NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
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G |
CEBPB |
CCAAT enhancer binding protein beta |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPB protein; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPB protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [N-acetylsphingosine results in decreased localization of CEBPB protein] |
CTD |
PMID:11779194 PMID:15319326 |
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NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
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G |
CEBPD |
CCAAT enhancer binding protein delta |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPD protein; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPD protein] |
CTD |
PMID:11779194 |
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NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164
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G |
CEBPE |
CCAAT enhancer binding protein epsilon |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of CEBPE protein] |
CTD |
PMID:20945414 |
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NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,036...23,120,256
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G |
CENPA |
centromere protein A |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067
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G |
CERS6 |
ceramide synthase 6 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CERS6 protein affects the expression of ABCB1 protein] |
CTD |
PMID:34915026 |
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NCBI chr 2:168,456,272...168,775,134
Ensembl chr 2:168,456,249...168,775,134
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G |
CFLAR |
CASP8 and FADD like apoptosis regulator |
affects expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of CFLAR protein alternative form benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of CFLAR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alvocidib results in decreased expression of CFLAR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of CFLAR protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [shogaol results in decreased expression of CFLAR protein modified form] |
CTD |
PMID:16951203 PMID:17510429 PMID:18980244 PMID:25619640 PMID:26415225 |
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NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
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G |
CFTR |
CF transmembrane conductance regulator |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] |
CTD |
PMID:18230692 |
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NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
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G |
CHEK1 |
checkpoint kinase 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHEK1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
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G |
CHRM2 |
cholinergic receptor muscarinic 2 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHRM2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255
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G |
CHUK |
component of inhibitor of nuclear factor kappa B kinase complex |
increases activity |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CHUK protein |
CTD |
PMID:24085292 |
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NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
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G |
CIDEA |
cell death inducing DFFA like effector a |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CIDEA mRNA |
CTD |
PMID:25566086 |
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NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
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G |
CITED4 |
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CITED4 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363
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G |
CKB |
creatine kinase B |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CKB mRNA |
CTD |
PMID:25566086 |
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NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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G |
CKMT2 |
creatine kinase, mitochondrial 2 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398
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G |
CLDN4 |
claudin 4 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690
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G |
CLDN5 |
claudin 5 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein] |
CTD |
PMID:34391839 |
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NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
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G |
CLIP4 |
CAP-Gly domain containing linker protein family member 4 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CLIP4 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 2:29,097,726...29,183,808
Ensembl chr 2:29,097,705...29,199,777
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G |
CMYA5 |
cardiomyopathy associated 5 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CMYA5 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 5:79,689,836...79,800,222
Ensembl chr 5:79,689,836...79,800,240
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G |
CNR1 |
cannabinoid receptor 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased expression of CNR1 mRNA] |
CTD |
PMID:21525939 |
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NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
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G |
CNR2 |
cannabinoid receptor 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased expression of CNR2 mRNA] |
CTD |
PMID:21525939 |
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NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
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G |
COL1A1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] |
CTD |
PMID:11306436 |
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NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
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G |
COMMD1 |
copper metabolism domain containing 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of COMMD1 protein |
CTD |
PMID:23401744 |
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NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247
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G |
CORIN |
corin, serine peptidase |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106
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G |
COX4I2 |
cytochrome c oxidase subunit 4I2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of COX4I2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr20:31,637,912...31,645,006
Ensembl chr20:31,637,912...31,645,006
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G |
CPXM1 |
carboxypeptidase X, M14 family member 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CPXM1 mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr20:2,794,074...2,800,627
Ensembl chr20:2,794,074...2,800,627
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G |
CRCT1 |
cysteine rich C-terminal 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CRCT1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:152,514,482...152,516,008
Ensembl chr 1:152,514,482...152,516,008
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G |
CREBBP |
CREB binding protein |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Valproic Acid results in decreased expression of CREBBP protein] |
CTD |
PMID:27381264 |
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NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
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G |
CRIP2 |
cysteine rich protein 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRIP2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr14:105,472,945...105,480,170
Ensembl chr14:105,472,962...105,480,162
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G |
CRYAA |
crystallin alpha A |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRYAA mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRYAA protein |
CTD |
PMID:15914627 |
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NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805
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G |
CRYAB |
crystallin alpha B |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CRYAB mRNA |
CTD |
PMID:15914627 |
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NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
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G |
CSNK2B |
casein kinase 2 beta |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in increased degradation of CSNK2B protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNFAIP1 protein results in increased degradation of CSNK2B protein] |
CTD |
PMID:37302538 |
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NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343
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G |
CST5 |
cystatin D |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CST5 mRNA |
CTD |
PMID:31806706 |
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NCBI chr20:23,875,934...23,879,748
Ensembl chr20:23,875,934...23,879,748
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G |
CTNNB1 |
catenin beta 1 |
multiple interactions decreases degradation |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [bruceine D affects the reaction [Oxygen deficiency affects the expression of CTNNB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arctigenin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Aspirin results in increased ubiquitination of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RASSF5 protein results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Nitroglycerin results in increased degradation of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of CTNNB1 protein; thymoquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CTNNB1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the phosphorylation of and affects the localization of CTNNB1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of CTNNB1 protein; Phenobarbital inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CTNNB1 protein] |
CTD |
PMID:14555707 PMID:16878161 PMID:17030184 PMID:17219422 PMID:20510325 PMID:21472727 PMID:25217643 PMID:26990689 PMID:27693619 PMID:28343033 PMID:28548306 PMID:31115591 PMID:32112862 PMID:34900531 More...
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NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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G |
CTSD |
cathepsin D |
increases cleavage multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]; ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]; ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein] |
CTD |
PMID:27638906 |
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NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
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G |
CUL2 |
cullin 2 |
multiple interactions |
EXP |
CUL2 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MAF1 protein] |
CTD |
PMID:31645432 |
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NCBI chr10:35,008,551...35,127,006
Ensembl chr10:35,008,504...35,127,006
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G |
CX3CL1 |
C-X3-C motif chemokine ligand 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CX3CL1 mRNA] |
CTD |
PMID:11698246 |
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NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] |
CTD |
PMID:11698246 |
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NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CXCL12 mRNA |
CTD |
PMID:25566086 |
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NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
multiple interactions increases expression increases secretion |
EXP |
Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Antimycin A inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chloroquine results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Titanium results in increased secretion of CXCL8 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; diphenyleneiodonium inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Glutathione inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Rotenone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased secretion of CXCL8 protein |
CTD |
PMID:11698246 PMID:12208513 PMID:15139008 PMID:16392133 PMID:18457675 PMID:24085292 More...
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NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CXCR4 |
C-X-C motif chemokine receptor 4 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TPD7 compound results in decreased expression of CXCR4 protein] |
CTD |
PMID:25753200 |
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NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
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G |
CYCS |
cytochrome c, somatic |
affects localization |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of CYCS protein |
CTD |
PMID:15725397 |
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NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
multiple interactions increases expression increases activity |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Harmine results in decreased stability of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [harmol results in decreased stability of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CYP1A1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CYP1A1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CYP1A1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Lead results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:10722677 PMID:10777561 PMID:16093525 PMID:16891617 PMID:17606337 PMID:18835339 PMID:22001777 PMID:22037238 More...
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NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
increases expression |
ISO |
MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats |
RGD |
PMID:22079846 |
RGD:401794136 |
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
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G |
CYP1B1 |
cytochrome P450 family 1 subfamily B member 1 |
increases stability |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of CYP1B1 protein |
CTD |
PMID:15486049 |
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NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
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G |
CYP26A1 |
cytochrome P450 family 26 subfamily A member 1 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CYP26A1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
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G |
CYP2B6 |
cytochrome P450 family 2 subfamily B member 6 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA] |
CTD |
PMID:24224465 |
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NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
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G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:24224465 |
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NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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G |
DDC |
dopa decarboxylase |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of DDC mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions increases expression increases activity |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of DDIT3 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 protein |
CTD |
PMID:17912641 PMID:19135031 PMID:19139269 PMID:22959925 PMID:23684743 PMID:25566086 PMID:27638906 More...
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
DFFA |
DNA fragmentation factor subunit alpha |
multiple interactions |
ISO |
DFFA protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DFFB protein] |
CTD |
PMID:18178165 |
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NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529
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G |
DFFB |
DNA fragmentation factor subunit beta |
multiple interactions decreases degradation increases ubiquitination |
ISO |
DFFA protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DFFB protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of DFFB protein |
CTD |
PMID:18178165 |
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NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429
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G |
DIABLO |
diablo IAP-binding mitochondrial protein |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cannabidiol promotes the reaction [DIABLO protein binds to XIAP protein]] |
CTD |
PMID:31699976 |
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NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
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G |
DIO2 |
iodothyronine deiodinase 2 |
multiple interactions increases expression increases activity |
EXP ISO |
[Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [2,2',4,4',5-brominated diphenyl ether metabolite results in decreased activity of DIO2 protein]; [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased activity of DIO2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [decabromobiphenyl ether results in increased degradation of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Thyroxine results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased activity of DIO2 protein; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DIO2 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of DIO2 protein |
CTD |
PMID:11425850 PMID:17615150 PMID:26004626 PMID:37330034 |
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NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
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G |
DNAJB1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 protein |
CTD |
PMID:15525353 PMID:25566086 |
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NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391
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G |
DNAJC2 |
DnaJ heat shock protein family (Hsp40) member C2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJC2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:103,312,289...103,344,767
Ensembl chr 7:103,312,289...103,344,830
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G |
DNAJC7 |
DnaJ heat shock protein family (Hsp40) member C7 |
multiple interactions increases ubiquitination |
ISO |
1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [DNAJC7 protein results in increased expression of NR1I3 protein]; NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]] |
CTD |
PMID:24789201 |
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NCBI chr17:41,976,435...42,017,439
Ensembl chr17:41,976,421...42,021,376
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G |
DNMT1 |
DNA methyltransferase 1 |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein] |
CTD |
PMID:19417133 PMID:21150308 PMID:23395981 |
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NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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G |
DNMT3A |
DNA methyltransferase 3 alpha |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3A protein] |
CTD |
PMID:23395981 |
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NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
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G |
DNMT3B |
DNA methyltransferase 3 beta |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3B protein] |
CTD |
PMID:23395981 |
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NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
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G |
DNMT3L |
DNA methyltransferase 3 like |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNMT3L mRNA] |
CTD |
PMID:25566086 |
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NCBI chr21:44,246,339...44,261,897
Ensembl chr21:44,246,339...44,262,216
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G |
DPP7 |
dipeptidyl peptidase 7 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] |
CTD |
PMID:16725115 |
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NCBI chr 9:137,110,546...137,118,306
Ensembl chr 9:137,110,542...137,118,309
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G |
DUSP1 |
dual specificity phosphatase 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SKP2 protein results in decreased expression of DUSP1 protein] |
CTD |
PMID:34697729 |
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NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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G |
DYNC1H1 |
dynein cytoplasmic 1 heavy chain 1 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr14:101,964,573...102,056,443
Ensembl chr14:101,964,573...102,056,443
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G |
DYNC1I1 |
dynein cytoplasmic 1 intermediate chain 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1I1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322
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G |
E2F1 |
E2F transcription factor 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dronabinol results in decreased expression of E2F1 protein] |
CTD |
PMID:17934890 |
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NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
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G |
E2F2 |
E2F transcription factor 2 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of E2F2 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233
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G |
EDN1 |
endothelin 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EDN1 mRNA |
CTD |
PMID:18457675 |
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NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
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G |
EGF |
epidermal growth factor |
multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EGF mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] |
CTD |
PMID:22689575 PMID:22766066 PMID:31806706 |
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NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
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G |
EGFL7 |
EGF like domain multiple 7 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of EGFL7 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 9:136,658,856...136,672,678
Ensembl chr 9:136,658,856...136,672,678
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G |
EGFR |
epidermal growth factor receptor |
multiple interactions decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MUC1 affects the expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGFR protein |
CTD |
PMID:17146438 PMID:20332299 PMID:22457794 PMID:28711525 |
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NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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G |
EGLN1 |
egl-9 family hypoxia inducible factor 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
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G |
EGLN3 |
egl-9 family hypoxia inducible factor 3 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
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G |
EIF2AK2 |
eukaryotic translation initiation factor 2 alpha kinase 2 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of EIF2AK2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2AK3 protein 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:22959925 PMID:27638906 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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G |
EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EIF2S1 protein modified form |
CTD |
PMID:21090173 PMID:22321511 PMID:23684743 PMID:25568320 PMID:27638906 PMID:28359145 More...
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NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
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G |
EIF4E |
eukaryotic translation initiation factor 4E |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] |
CTD |
PMID:15878868 |
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NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
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G |
ELAVL1 |
ELAV like RNA binding protein 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ELAVL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ELAVL1 protein |
CTD |
PMID:23922739 |
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NCBI chr19:7,958,573...8,005,641
Ensembl chr19:7,958,573...8,005,659
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G |
EMCN |
endomucin |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EMCN mRNA |
CTD |
PMID:25566086 |
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NCBI chr 4:100,395,341...100,518,022
Ensembl chr 4:100,395,341...100,880,126
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G |
ENO3 |
enolase 3 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
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G |
EP300 |
E1A binding protein p300 |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased degradation of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SIRT6 protein results in decreased expression of EP300 protein] |
CTD |
PMID:15767673 PMID:17927689 PMID:27094368 |
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NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077
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G |
EPAS1 |
endothelial PAS domain protein 1 |
multiple interactions increases ubiquitination increases expression increases hydroxylation increases stability |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPAS1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; [Formaldehyde co-treated with VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; [VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [MALAT1 mRNA promotes the reaction [sodium arsenite results in increased expression of EPAS1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of EPAS1 protein]; MALAT1 mRNA promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]; MALAT1 mRNA promotes the reaction [sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]]; sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of EPAS1 protein |
CTD |
PMID:22447124 PMID:23545307 PMID:26735578 PMID:35504338 |
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NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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G |
EPHB4 |
EPH receptor B4 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Homoharringtonine results in decreased expression of EPHB4 protein] |
CTD |
PMID:31726078 |
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NCBI chr 7:100,802,565...100,827,523
Ensembl chr 7:100,802,565...100,827,523
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G |
EPHX1 |
epoxide hydrolase 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
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G |
EPHX2 |
epoxide hydrolase 2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX2 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
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G |
EPO |
erythropoietin |
multiple interactions increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of EPO protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPO protein |
CTD |
PMID:31850806 PMID:32461003 |
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NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
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G |
EPPK1 |
epiplakin 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EPPK1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 8:143,857,324...143,879,194
Ensembl chr 8:143,857,324...143,878,467
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G |
ERBB2 |
erb-b2 receptor tyrosine kinase 2 |
decreases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Berberine results in decreased expression of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [demethoxycurcumin results in increased degradation of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB2 protein] |
CTD |
PMID:18655187 PMID:20332299 PMID:31806706 PMID:33325633 PMID:34291863 |
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NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
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G |
ERBB3 |
erb-b2 receptor tyrosine kinase 3 |
multiple interactions decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of ERBB3 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB3 protein |
CTD |
PMID:20332299 |
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NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
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G |
ERCC6 |
ERCC excision repair 6, chromatin remodeling factor |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein] |
CTD |
PMID:25440059 |
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NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions increases phosphorylation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ERN1 protein ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]; ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of ERN1 protein |
CTD |
PMID:19139269 PMID:27638906 |
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NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
ESR1 |
estrogen receptor 1 |
multiple interactions increases ubiquitination decreases expression increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-prenylnaringenin results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [8-prenylnaringenin results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [baohuoside I results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Butyrophenones results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [AHR protein results in increased expression of ESR1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fulvestrant results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Okadaic Acid results in increased degradation of ESR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Plant Extracts results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [xanthohumol results in decreased expression of ESR1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of ESR1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ESR1 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in increased degradation of ESR1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [PTK2B protein affects the ubiquitination of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gonadotropin-Releasing Hormone results in decreased expression of ESR1 protein] |
CTD |
PMID:12612060 PMID:14702340 PMID:14750165 PMID:15965230 PMID:16055746 PMID:16965676 PMID:20419096 PMID:21041310 PMID:26990689 PMID:29428397 PMID:31806706 PMID:32986415 PMID:34801851 PMID:35802278 More...
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
ESR2 |
estrogen receptor 2 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Estradiol results in increased expression of ESR2 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR2 protein |
CTD |
PMID:14702340 PMID:15207704 |
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NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
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G |
ESRRA |
estrogen related receptor alpha |
increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESRRA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HDAC6 protein results in increased expression of ESRRA protein] |
CTD |
PMID:34524571 |
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NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743
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G |
FAHD1 |
fumarylacetoacetate hydrolase domain containing 1 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of FAHD1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:1,827,206...1,840,207
Ensembl chr16:1,826,967...1,840,207
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G |
FAM13B |
family with sequence similarity 13 member B |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of FAM13B mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:137,937,960...138,052,178
Ensembl chr 5:137,937,960...138,051,961
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G |
FAM78A |
family with sequence similarity 78 member A |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FAM78A mRNA |
CTD |
PMID:25566086 |
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NCBI chr 9:131,258,078...131,281,045
Ensembl chr 9:131,258,076...131,277,365
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G |
FASLG |
Fas ligand |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased expression of FASLG protein] |
CTD |
PMID:20005289 |
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NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FBXL12 |
F-box and leucine rich repeat protein 12 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXL12 mRNA |
CTD |
PMID:20061341 |
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NCBI chr19:9,810,270...9,819,079
Ensembl chr19:9,810,267...9,827,816
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G |
FBXO10 |
F-box protein 10 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXO10 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 9:37,510,892...37,576,380
Ensembl chr 9:37,510,892...37,576,380
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G |
FBXO2 |
F-box protein 2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FBXO2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:11,648,387...11,654,429
Ensembl chr 1:11,637,018...11,655,785
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G |
FBXO32 |
F-box protein 32 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [FBXO32 protein results in decreased expression of KCNN2 protein] |
CTD |
PMID:30635400 |
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NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
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G |
FBXO6 |
F-box protein 6 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FBXO6 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:11,664,200...11,674,354
Ensembl chr 1:11,664,200...11,674,354
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G |
FBXW7 |
F-box and WD repeat domain containing 7 |
multiple interactions |
ISO |
FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]] |
CTD |
PMID:24457827 |
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NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
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G |
FHL2 |
four and a half LIM domains 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FHL2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513
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G |
FIS1 |
fission, mitochondrial 1 |
multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[ponasterone A results in increased expression of PINK1 protein] which results in decreased expression of FIS1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FIS1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[PARK protein co-treated with UBB protein] results in decreased expression of FIS1 protein] |
CTD |
PMID:20164189 |
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NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
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G |
FLNC |
filamin C |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FLNC mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274
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G |
FN1 |
fibronectin 1 |
decreases secretion |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased secretion of FN1 protein |
CTD |
PMID:11594554 |
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NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hydrogen Peroxide results in increased expression of FOS protein] [Arachidonic Acid co-treated with Quercetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of FOS protein |
CTD |
PMID:15136564 PMID:20551291 |
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NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
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G |
FOSL1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]] |
CTD |
PMID:17148446 |
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NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
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G |
FOXM1 |
forkhead box M1 |
multiple interactions decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [palbociclib results in decreased expression of FOXM1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FOXM1 mRNA |
CTD |
PMID:22094256 PMID:31806706 |
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NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174
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G |
FOXO1 |
forkhead box O1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [dorsomorphin results in decreased expression of FOXO1 protein] |
CTD |
PMID:25065674 |
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NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
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G |
FOXO3 |
forkhead box O3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO3 protein] |
CTD |
PMID:31421153 |
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NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
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G |
FSD2 |
fibronectin type III and SPRY domain containing 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FSD2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr15:82,755,362...82,806,069
Ensembl chr15:82,755,362...82,806,070
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G |
FTH1 |
ferritin heavy chain 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein] |
CTD |
PMID:16707465 |
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NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
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G |
FTL |
ferritin light chain |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein] |
CTD |
PMID:16707465 |
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NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
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G |
FUNDC1 |
FUN14 domain containing 1 |
multiple interactions increases expression |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Rotenone] results in increased expression of FUNDC1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Rotenone results in decreased expression of FUNDC1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FUNDC1 protein |
CTD |
PMID:32001317 PMID:37156403 |
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NCBI chr X:44,523,639...44,542,859
Ensembl chr X:44,523,639...44,542,859
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G |
G0S2 |
G0/G1 switch 2 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of G0S2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390
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G |
GABARAPL1 |
GABA type A receptor associated protein like 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GABARAPL1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr12:10,212,877...10,223,128
Ensembl chr12:10,212,458...10,223,128
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G |
GABBR2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction and affects the localization of [PSMC5 protein binds to GABBR2 protein] |
CTD |
PMID:24482233 |
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NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935
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G |
GAD1 |
glutamate decarboxylase 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] |
CTD |
PMID:29107683 |
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NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
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G |
GAD2 |
glutamate decarboxylase 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD2 protein] |
CTD |
PMID:29107683 |
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NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558
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G |
GADD45A |
growth arrest and DNA damage inducible alpha |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GADD45A mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
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G |
GADD45G |
growth arrest and DNA damage inducible gamma |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of GADD45G mRNA |
CTD |
PMID:25566086 |
|
NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
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G |
GCLC |
glutamate-cysteine ligase catalytic subunit |
multiple interactions increases expression |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLC mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC protein |
CTD |
PMID:25263748 PMID:30186748 PMID:33434570 |
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NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
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G |
GCLM |
glutamate-cysteine ligase modifier subunit |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM protein |
CTD |
PMID:20061341 PMID:33434570 |
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NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
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G |
GDF15 |
growth differentiation factor 15 |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
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G |
GJA1 |
gap junction protein alpha 1 |
multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [antofine results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ioxynil analog results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ioxynil results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in decreased expression of GJA1 protein] |
CTD |
PMID:15685554 PMID:20510257 PMID:23403203 PMID:29180066 |
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NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
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G |
GJA5 |
gap junction protein alpha 5 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GJA5 mRNA |
CTD |
PMID:25566086 |
|
NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
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G |
GLS |
glutaminase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diphenylarsinic acid results in increased degradation of GLS protein alternative form] |
CTD |
PMID:22493432 |
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NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
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G |
GPR146 |
G protein-coupled receptor 146 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of GPR146 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:1,044,546...1,059,261
Ensembl chr 7:1,044,546...1,059,261
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G |
GPX1 |
glutathione peroxidase 1 |
increases expression multiple interactions decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GPX1 mRNA [sodium arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of GPX1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of GPX1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in decreased expression of GPX1 mRNA]; sodium arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GPX1 protein]; sodium arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GPX1 mRNA] |
CTD |
PMID:32301004 |
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NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
GRIA1 |
glutamate ionotropic receptor AMPA type subunit 1 |
increases localization |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA1 protein |
CTD |
PMID:19674091 |
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NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
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G |
GRIA2 |
glutamate ionotropic receptor AMPA type subunit 2 |
increases localization |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA2 protein |
CTD |
PMID:19674091 |
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NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
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G |
GRIP1 |
glutamate receptor interacting protein 1 |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GRIP1 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [GRIP1 protein binds to NR1I3 protein] |
CTD |
PMID:24224465 PMID:25566086 |
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NCBI chr12:66,347,431...67,069,338
Ensembl chr12:66,347,431...67,069,162
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G |
GSDMD |
gasdermin D |
multiple interactions |
EXP |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of and results in increased cleavage of GSDMD protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of GSDMD protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of and results in increased cleavage of GSDMD protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of GSDMD protein] |
CTD |
PMID:34920032 |
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NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
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G |
GSG1L |
GSG1 like |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSG1L mRNA] |
CTD |
PMID:25566086 |
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NCBI chr16:27,787,528...28,063,714
Ensembl chr16:27,787,528...28,063,714
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G |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of GSK3B protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSK3B protein modified form |
CTD |
PMID:24085292 PMID:26990689 PMID:30703377 |
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NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
GSR |
glutathione-disulfide reductase |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR protein [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GSR mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GSR protein |
CTD |
PMID:20061341 PMID:33434570 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
GSS |
glutathione synthetase |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSS mRNA |
CTD |
PMID:20061341 |
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NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
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G |
GSTA2 |
glutathione S-transferase alpha 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA2 mRNA |
CTD |
PMID:12446695 |
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NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
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G |
GSTA3 |
glutathione S-transferase alpha 3 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA3 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]] |
CTD |
PMID:16243960 PMID:20061341 |
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NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698
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G |
GSTM1 |
glutathione S-transferase mu 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
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G |
GSTM2 |
glutathione S-transferase mu 2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM5 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
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G |
GSTM3 |
glutathione S-transferase mu 3 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM3 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
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G |
GSTO1 |
glutathione S-transferase omega 1 |
increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTO1 mRNA [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GSTO1 mRNA |
CTD |
PMID:33434570 |
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NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
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G |
GSTO2 |
glutathione S-transferase omega 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTO2 mRNA |
CTD |
PMID:33434570 |
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NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950
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G |
GSTP1 |
glutathione S-transferase pi 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTP1 protein |
CTD |
PMID:15863507 |
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NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
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G |
GUCY1A1 |
guanylate cyclase 1 soluble subunit alpha 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059
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G |
GYG1 |
glycogenin 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG1 mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr 3:148,991,540...149,031,775
Ensembl chr 3:148,991,408...149,031,775
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G |
H19 |
H19 imprinted maternally expressed transcript |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H19 mRNA |
CTD |
PMID:25566086 |
|
NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552
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G |
H2AC11 |
H2A clustered histone 11 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC22 mRNA |
CTD |
PMID:25566086 |
|
NCBI chr 6:27,133,043...27,133,535
Ensembl chr 6:27,133,043...27,133,535
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G |
H2AC12 |
H2A clustered histone 12 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC12 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 6:27,147,106...27,147,562
Ensembl chr 6:27,147,106...27,147,562
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G |
H2AC14 |
H2A clustered histone 14 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC13 mRNA |
CTD |
PMID:25566086 |
|
NCBI chr 6:27,814,302...27,814,777
Ensembl chr 6:27,814,302...27,814,777
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G |
H2AC15 |
H2A clustered histone 15 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC15 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 6:27,837,880...27,838,375
Ensembl chr 6:27,837,880...27,838,375
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G |
H2AC7 |
H2A clustered histone 7 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC7 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 6:26,198,784...26,199,293
Ensembl chr 6:26,198,784...26,199,293
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G |
H2AX |
H2A.X variant histone |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein] |
CTD |
PMID:17875725 PMID:21227924 |
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NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
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G |
H4C16 |
H4 histone 16 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased acetylation of H4C16 protein] |
CTD |
PMID:15857753 |
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NCBI chr12:14,770,720...14,771,131
Ensembl chr12:14,767,999...14,771,131
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G |
HAGHL |
hydroxyacylglutathione hydrolase like |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HAGHL mRNA |
CTD |
PMID:25566086 |
|
NCBI chr16:727,106...729,715
Ensembl chr16:726,936...735,525
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G |
HAX1 |
HCLS1 associated protein X-1 |
affects expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of HAX1 protein |
CTD |
PMID:19763263 |
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NCBI chr 1:154,272,629...154,275,875
Ensembl chr 1:154,272,355...154,275,875
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G |
HDAC1 |
histone deacetylase 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Particulate Matter results in increased degradation of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vehicle Emissions results in increased degradation of HDAC1 protein] |
CTD |
PMID:17395887 PMID:17927689 |
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NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
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G |
HDAC2 |
histone deacetylase 2 |
increases ubiquitination multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HDAC2 protein [SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Smoke results in increased degradation of and results in decreased expression of HDAC2 protein]; CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein] |
CTD |
PMID:18421014 PMID:24973648 |
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NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
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G |
HDAC6 |
histone deacetylase 6 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HDAC6 protein results in increased expression of ESRRA protein] |
CTD |
PMID:34524571 |
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NCBI chr X:48,801,398...48,824,982
Ensembl chr X:48,801,377...48,824,982
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G |
HES1 |
hes family bHLH transcription factor 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HES1 mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
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G |
HIF1A |
hypoxia inducible factor 1 subunit alpha |
decreases degradation multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of HIF1A protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form 3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; [andrographolide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HIF1A protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Oxygen deficiency] affects the expression of HIF1A protein; [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of HIF1A protein; [Formaldehyde co-treated with VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of HIF1A protein; [Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein; [VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [[Apigenin co-treated with Oxygen deficiency] affects the expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of HIF1A protein; bruceine D inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]; diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; dictamnine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Digitoxin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; dihydrotanshinone I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; genipin affects the reaction [[Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein]; Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]]; Resveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of HIF1A protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein] |
CTD |
PMID:11980636 PMID:17764071 PMID:17973296 PMID:18682687 PMID:19254699 PMID:19263519 PMID:20335389 PMID:20524035 PMID:20554536 PMID:21134392 PMID:22537771 PMID:23593480 PMID:24221993 PMID:24497960 PMID:24975222 PMID:25192544 PMID:26282490 PMID:27287256 PMID:28574600 PMID:28651835 PMID:29630948 PMID:30266538 PMID:31850806 PMID:32461003 PMID:34717917 PMID:34900531 PMID:35504338 PMID:35513012 More...
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NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
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G |
HIGD1B |
HIG1 hypoxia inducible domain family member 1B |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA] |
CTD |
PMID:25566086 |
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NCBI chr17:44,844,860...44,850,476
Ensembl chr17:44,846,353...44,850,476
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G |
HIPK2 |
homeodomain interacting protein kinase 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein] |
CTD |
PMID:19714248 |
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NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
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G |
HLA-DQB1 |
major histocompatibility complex, class II, DQ beta 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H2-AB1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
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G |
HMOX1 |
heme oxygenase 1 |
increases expression increases ubiquitination multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in decreased expression of HMOX1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hemin results in decreased expression of HMOX1 protein] [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of HMOX1 mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of HMOX1 protein; [USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; [USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; Arsenic inhibits the reaction [[USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [[USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hemin results in increased expression of HMOX1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]; HMOX1 protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA]; USP7 protein affects the reaction [Arsenic inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]]; USP7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of HMOX1 mRNA] |
CTD |
PMID:12441344 PMID:18550526 PMID:18835339 PMID:25824035 PMID:30186748 PMID:33434570 PMID:35821281 More...
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HNRNPA1 |
heterogeneous nuclear ribonucleoprotein A1 |
multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetracaine results in decreased expression of HNRNPA1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Thapsigargin affects the localization of HNRNPA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tunicamycin affects the localization of HNRNPA1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HNRNPA1 mRNA |
CTD |
PMID:23106379 PMID:34822839 |
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NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
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G |
HNRNPK |
heterogeneous nuclear ribonucleoprotein K |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of HNRNPK protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [PRKCD protein results in increased ubiquitination of HNRNPK protein] |
CTD |
PMID:19747914 |
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NCBI chr 9:83,968,083...83,980,615
Ensembl chr 9:83,968,083...83,980,631
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G |
HOPX |
HOP homeobox |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HOPX mRNA |
CTD |
PMID:25566086 |
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NCBI chr 4:56,647,998...56,681,706
Ensembl chr 4:56,647,989...56,681,877
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G |
HP |
haptoglobin |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HP mRNA |
CTD |
PMID:20061341 |
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NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
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G |
HR |
HR lysine demethylase and nuclear receptor corepressor |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384
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G |
HSD11B2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased expression of HSD11B2 mRNA] |
CTD |
PMID:15857753 |
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NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
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G |
HSF1 |
heat shock transcription factor 1 |
increases activity multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of HSF1 protein HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 mRNA]; HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBC mRNA] |
CTD |
PMID:11893605 PMID:30186748 |
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NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720
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G |
HSF2 |
heat shock transcription factor 2 |
increases activity increases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of HSF2 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF2 protein Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF2 protein] |
CTD |
PMID:11893605 PMID:15914627 |
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NCBI chr 6:122,399,551...122,433,119
Ensembl chr 6:122,399,551...122,433,119
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G |
HSF4 |
heat shock transcription factor 4 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF4 protein Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF4 protein] |
CTD |
PMID:15914627 |
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NCBI chr16:67,163,761...67,169,941
Ensembl chr16:67,164,681...67,169,945
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G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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G |
HSPA1A |
heat shock protein family A (Hsp70) member 1A |
multiple interactions increases expression |
ISO |
PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A mRNA |
CTD |
PMID:18331584 PMID:25566086 |
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NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
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G |
HSPA1B |
heat shock protein family A (Hsp70) member 1B |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1B mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1B protein |
CTD |
PMID:15525353 PMID:25566086 |
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NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
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G |
HSPA4 |
heat shock protein family A (Hsp70) member 4 |
multiple interactions increases expression |
ISO EXP |
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 protein] HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 mRNA] |
CTD |
PMID:15914627 PMID:30186748 |
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NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA5 protein |
CTD |
PMID:19139269 PMID:21692457 |
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
HSPA8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of HSPA8 mRNA |
CTD |
PMID:25566086 |
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NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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G |
HSPA9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in decreased expression of HSPA9 protein] |
CTD |
PMID:37353096 |
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NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
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G |
HSPB1 |
heat shock protein family B (small) member 1 |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [bufalin results in decreased expression of HSPB1 protein] Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 protein] |
CTD |
PMID:15914627 PMID:23091618 |
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NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
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G |
HSPB2 |
heat shock protein family B (small) member 2 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr11:111,912,734...111,914,093
Ensembl chr11:111,912,734...111,914,093
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G |
HSPH1 |
heat shock protein family H (Hsp110) member 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPH1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
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G |
HTRA2 |
HtrA serine peptidase 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HTRA2 protein |
CTD |
PMID:19763263 |
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NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350
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G |
ICAM1 |
intercellular adhesion molecule 1 |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] MG132 pretreatment decreases expression of protein in liver of intestinal ischemia/reperfusion rats |
CTD RGD |
PMID:11698246 PMID:14572618 PMID:22079846 |
RGD:401794136 |
NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
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G |
IFNG |
interferon gamma |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]] |
CTD |
PMID:15914627 PMID:19393675 PMID:23395999 |
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IGF1R |
insulin like growth factor 1 receptor |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein] |
CTD |
PMID:28711525 |
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NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
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G |
IGF2 |
insulin like growth factor 2 |
multiple interactions decreases response to substance |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to IGF2 protein |
CTD |
PMID:24055520 |
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NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391
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G |
IL18 |
interleukin 18 |
multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein] [lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of IL18 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of IL18 protein] |
CTD |
PMID:15178407 PMID:34920032 |
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NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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G |
IL1A |
interleukin 1 alpha |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IL1A mRNA |
CTD |
PMID:11230753 PMID:15728660 PMID:20061341 |
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NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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G |
IL1B |
interleukin 1 beta |
multiple interactions decreases response to substance |
EXP ISO |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of IL1B protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of IL1B protein]; sodium arsenite inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to IL1B protein |
CTD |
PMID:10541287 PMID:11835394 PMID:14581482 PMID:19393675 PMID:23395999 PMID:34920032 More...
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL6 |
interleukin 6 |
increases expression decreases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 protein MG132 pretreatment decreases expression of TNFa, IL6 protein in serum of intestinal ischemia/reperfusion rats benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein] Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 protein] |
CTD RGD |
PMID:11893605 PMID:18457675 PMID:28134560 PMID:31806706 PMID:22079846 |
RGD:401794136 |
NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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G |
IMPACT |
impact RWD domain protein |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IMPACT mRNA |
CTD |
PMID:25566086 |
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NCBI chr18:24,426,670...24,453,531
Ensembl chr18:24,426,634...24,453,531
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G |
INAFM2 |
InaF motif containing 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of INAFM2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr15:40,323,692...40,326,715
Ensembl chr15:40,323,692...40,326,715
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G |
INS |
insulin |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]] |
CTD |
PMID:22537771 |
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NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
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G |
INS-IGF2 |
INS-IGF2 readthrough |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [INS1 protein results in decreased expression of IRS1 protein] |
CTD |
PMID:24219910 |
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NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
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G |
INSL6 |
insulin like 6 |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of INSL6 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 9:4,991,976...5,185,639
Ensembl chr 9:5,123,880...5,185,647
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G |
IRF8 |
interferon regulatory factor 8 |
decreases degradation |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of IRF8 protein |
CTD |
PMID:15837792 |
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NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606
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G |
IRS1 |
insulin receptor substrate 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [INS1 protein results in decreased expression of IRS1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of IRS1 protein] |
CTD |
PMID:24219910 PMID:32061799 |
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NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
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G |
IRX3 |
iroquois homeobox 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IRX3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:54,283,304...54,286,787
Ensembl chr16:54,283,304...54,286,787
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G |
ITGAM |
integrin subunit alpha M |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of ITGAM protein] |
CTD |
PMID:20945414 |
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NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
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G |
ITGB1BP2 |
integrin subunit beta 1 binding protein 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ITGB1BP2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr X:71,301,750...71,305,371
Ensembl chr X:71,301,750...71,305,371
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G |
ITPR3 |
inositol 1,4,5-trisphosphate receptor type 3 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in decreased expression of ITPR3 protein] |
CTD |
PMID:37353096 |
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NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
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G |
IVL |
involucrin |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IVL mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
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G |
JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KU-32 compound inhibits the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein] |
CTD |
PMID:23240583 PMID:23593480 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
JUNB |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]] |
CTD |
PMID:17148446 |
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NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
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G |
KAT5 |
lysine acetyltransferase 5 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KAT5 protein results in increased acetylation of and results in increased degradation of SRSF2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of KAT5 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KAT5 protein |
CTD |
PMID:21157427 PMID:28837777 |
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NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604
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G |
KATNB1 |
katanin regulatory subunit B1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KATNB1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:57,735,770...57,757,244
Ensembl chr16:57,735,739...57,757,244
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G |
KBTBD11 |
kelch repeat and BTB domain containing 11 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KBTBD11 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 8:1,973,677...2,006,936
Ensembl chr 8:1,973,677...2,006,936
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G |
KCNG2 |
potassium voltage-gated channel modifier subfamily G member 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KCNG2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr18:79,797,938...79,900,100
Ensembl chr18:79,797,938...79,900,184
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G |
KCNH2 |
potassium voltage-gated channel subfamily H member 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein] |
CTD |
PMID:28521025 |
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NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
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G |
KCNIP3 |
potassium voltage-gated channel interacting protein 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein] |
CTD |
PMID:30503815 |
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NCBI chr 2:95,297,347...95,386,077
Ensembl chr 2:95,297,327...95,386,077
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G |
KCNN2 |
potassium calcium-activated channel subfamily N member 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [FBXO32 protein results in decreased expression of KCNN2 protein] |
CTD |
PMID:30635400 |
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NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500
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G |
KDM1A |
lysine demethylase 1A |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SP2509 results in decreased stability of KDM1A protein] |
CTD |
PMID:29581250 |
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NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689
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G |
KEAP1 |
kelch like ECH associated protein 1 |
multiple interactions |
ISO |
[2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein] |
CTD |
PMID:18512965 |
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NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
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G |
KIF1A |
kinesin family member 1A |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293
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G |
KIF1B |
kinesin family member 1B |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1B mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
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G |
KIF20A |
kinesin family member 20A |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF20A mRNA |
CTD |
PMID:20061341 |
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NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
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G |
KIF4A |
kinesin family member 4A |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF4 mRNA |
CTD |
PMID:20061341 |
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NCBI chr X:70,290,104...70,420,886
Ensembl chr X:70,290,104...70,420,886
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G |
KLF2 |
KLF transcription factor 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TRAF2 protein results in decreased expression of KLF2 protein] |
CTD |
PMID:35635602 |
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NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
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G |
KLF6 |
KLF transcription factor 6 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KLF6 mRNA |
CTD |
PMID:31806706 |
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NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
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G |
KLHL6 |
kelch like family member 6 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KLHL6 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 3:183,487,551...183,555,706
Ensembl chr 3:183,487,551...183,555,706
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G |
KLK2 |
kallikrein related peptidase 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Testosterone results in increased expression of KLK2 mRNA] |
CTD |
PMID:12376534 |
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NCBI chr19:50,873,439...50,880,567
Ensembl chr19:50,861,568...50,880,567
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G |
KNSTRN |
kinetochore localized astrin (SPAG5) binding protein |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KNSTRN mRNA |
CTD |
PMID:20061341 |
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NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288
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G |
KRAS |
KRAS proto-oncogene, GTPase |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KRAS mRNA |
CTD |
PMID:31806706 |
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NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
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G |
KRT5 |
keratin 5 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [Diacetyl affects the expression of and affects the ubiquitination of KRT5 protein] |
CTD |
PMID:32112875 |
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NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530
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G |
KY |
kyphoscoliosis peptidase |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA |
CTD |
PMID:25566086 |
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NCBI chr 3:134,599,923...134,651,022
Ensembl chr 3:134,599,923...134,651,636
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G |
LAT2 |
linker for activation of T cells family member 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate results in decreased expression of LAT2 protein] |
CTD |
PMID:23001822 |
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NCBI chr 7:74,210,006...74,229,834
Ensembl chr 7:74,199,652...74,229,834
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G |
LDB3 |
LIM domain binding 3 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LDB3 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr10:86,666,788...86,736,072
Ensembl chr10:86,666,785...86,736,072
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G |
LGALS1 |
galectin 1 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LGALS1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
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G |
LMO7 |
LIM domain 7 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LMO7 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr13:75,620,434...75,859,870
Ensembl chr13:75,620,434...75,859,870
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G |
LNX1 |
ligand of numb-protein X 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LNX1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 4:53,459,301...53,652,477
Ensembl chr 4:53,459,301...53,701,405
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G |
LPIN1 |
lipin 1 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TGFB1 protein results in decreased expression of LPIN1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of LPIN1 protein |
CTD |
PMID:27345520 |
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NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
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G |
LRRC10 |
leucine rich repeat containing 10 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC10 mRNA; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr12:69,608,564...69,610,907
Ensembl chr12:69,608,564...69,610,907
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G |
LRRC75A |
leucine rich repeat containing 75A |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC75A mRNA |
CTD |
PMID:25566086 |
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NCBI chr17:16,441,577...16,492,193
Ensembl chr17:16,441,577...16,492,193
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G |
LRRK2 |
leucine rich repeat kinase 2 |
increases ubiquitination |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of LRRK2 protein |
CTD |
PMID:24942733 |
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NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285
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G |
LUC7L |
LUC7 like |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of LUC7L mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:188,990...229,449
Ensembl chr16:188,969...229,463
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G |
LXN |
latexin |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 3:158,666,414...158,672,648
Ensembl chr 3:158,645,822...158,672,648
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G |
MAF1 |
MAF1 homolog, negative regulator of RNA polymerase III |
multiple interactions |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Sirolimus] results in decreased degradation of MAF1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of and results in decreased degradation of MAF1 protein; CUL2 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MAF1 protein] |
CTD |
PMID:31645432 |
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NCBI chr 8:144,104,461...144,107,611
Ensembl chr 8:144,104,420...144,107,611
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G |
MALAT1 |
metastasis associated lung adenocarcinoma transcript 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [MALAT1 mRNA promotes the reaction [sodium arsenite results in increased expression of EPAS1 protein]]; MALAT1 mRNA promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]; MALAT1 mRNA promotes the reaction [sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]] |
CTD |
PMID:26735578 PMID:27287256 |
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NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
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G |
MAP1B |
microtubule associated protein 1B |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1LC3B protein modified form benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trovafloxacin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; MAP1LC3B protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:24085292 PMID:26409479 PMID:33609687 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:25780039 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:25780039 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
increases phosphorylation decreases response to substance multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein MAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] |
CTD |
PMID:18463101 PMID:23593480 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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G |
MAPK9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
MAPK9 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] |
CTD |
PMID:23593480 |
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NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
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G |
MAPKAPK2 |
MAPK activated protein kinase 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of MAPKAPK2 protein] |
CTD |
PMID:35427736 |
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NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281
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G |
MARCHF6 |
membrane associated ring-CH-type finger 6 |
increases stability |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of MARCHF6 protein |
CTD |
PMID:30545937 |
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NCBI chr 5:10,353,695...10,440,388
Ensembl chr 5:10,353,695...10,440,388
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G |
MASP1 |
MBL associated serine protease 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MASP1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
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G |
MB |
myoglobin |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA] |
CTD |
PMID:25566086 |
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NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
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G |
MBD2 |
methyl-CpG binding domain protein 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MBD2 protein] |
CTD |
PMID:23395981 |
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NCBI chr18:54,151,606...54,224,669
Ensembl chr18:54,151,606...54,224,669
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G |
MBD3 |
methyl-CpG binding domain protein 3 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MBD3 protein] |
CTD |
PMID:23395981 |
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NCBI chr19:1,573,596...1,592,865
Ensembl chr19:1,573,596...1,592,865
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G |
MCL1 |
MCL1 apoptosis regulator, BCL2 family member |
multiple interactions increases expression decreases degradation increases ubiquitination |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Resveratrol co-treated with Clofarabine] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[WEHI-539 co-treated with venetoclax] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Clofarabine promotes the reaction [Resveratrol results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Daunorubicin results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol promotes the reaction [Clofarabine results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [USP7 protein affects the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Resveratrol co-treated with Clofarabine] results in increased expression of MCL1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MCL1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of MCL1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MCL1 protein |
CTD |
PMID:16109713 PMID:17553788 PMID:20802529 PMID:21750559 PMID:21933852 PMID:23082001 PMID:23341456 PMID:23353698 PMID:24924397 PMID:25408576 PMID:28673964 PMID:32305283 PMID:32802178 PMID:34963561 PMID:35561756 PMID:36346691 More...
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NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
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G |
MCM5 |
minichromosome maintenance complex component 5 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MCM5 mRNA |
CTD |
PMID:25566086 |
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NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431
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G |
MDM2 |
MDM2 proto-oncogene |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MDM2 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] |
CTD |
PMID:17575151 PMID:20061341 |
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NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
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G |
MECP2 |
methyl-CpG binding protein 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MECP2 protein] |
CTD |
PMID:23395981 |
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NCBI chr X:154,021,573...154,097,717
Ensembl chr X:154,021,573...154,137,103
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G |
MGARP |
mitochondria localized glutamic acid rich protein |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGARP mRNA |
CTD |
PMID:25566086 |
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NCBI chr 4:139,266,165...139,280,225
Ensembl chr 4:139,266,165...139,280,225
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G |
MGLL |
monoglyceride lipase |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGLL mRNA |
CTD |
PMID:25566086 |
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NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
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G |
MGMT |
O-6-methylguanine-DNA methyltransferase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tamoxifen results in increased degradation of MGMT protein] |
CTD |
PMID:17597106 |
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NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
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G |
MGST1 |
microsomal glutathione S-transferase 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MGST1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
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G |
MIR122 |
microRNA 122 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MIR122 mRNA |
CTD |
PMID:31806706 |
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NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
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G |
MIR146A |
microRNA 146a |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MIR146A |
CTD |
PMID:32392329 |
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NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
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G |
MITF |
melanocyte inducing transcription factor |
multiple interactions decreases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MITF mRNA |
CTD |
PMID:29486182 PMID:31806706 |
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NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,456...69,968,336
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G |
MLKL |
mixed lineage kinase domain like pseudokinase |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA] |
CTD |
PMID:25566086 |
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NCBI chr16:74,671,855...74,700,862
Ensembl chr16:74,671,855...74,700,960
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G |
MLLT11 |
MLLT11 transcription factor 7 cofactor |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLLT11 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
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G |
MMP13 |
matrix metallopeptidase 13 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [halofuginone results in increased expression of MMP13 mRNA] |
CTD |
PMID:16489207 |
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NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
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G |
MMP23B |
matrix metallopeptidase 23B |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:1,632,173...1,634,654
Ensembl chr 1:1,632,163...1,635,263
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G |
MMP9 |
matrix metallopeptidase 9 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [butein results in decreased expression of MMP9 protein] |
CTD |
PMID:15728660 PMID:20696233 PMID:24613819 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MOCOS |
molybdenum cofactor sulfurase |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCOS mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr18:36,187,497...36,272,157
Ensembl chr18:36,187,497...36,272,157
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G |
MOCS1 |
molybdenum cofactor synthesis 1 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 6:39,904,170...39,934,462
Ensembl chr 6:39,899,578...39,934,551
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G |
MOCS2 |
molybdenum cofactor synthesis 2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:53,095,679...53,109,757
Ensembl chr 5:53,095,679...53,110,063
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G |
MT3 |
metallothionein 3 |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MT3 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
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G |
MTERF3 |
mitochondrial transcription termination factor 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MTERF3 protein] |
CTD |
PMID:35904214 |
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NCBI chr 8:96,239,398...96,261,613
Ensembl chr 8:96,239,398...96,261,610
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G |
MTHFD1 |
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of MTHFD1 protein] |
CTD |
PMID:28265077 |
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NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
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G |
MTOR |
mechanistic target of rapamycin kinase |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MTOR protein |
CTD |
PMID:25897075 |
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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G |
MTTP |
microsomal triglyceride transfer protein |
multiple interactions increases expression |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Chloroquine] results in increased expression of MTTP protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MTTP protein |
CTD |
PMID:34516972 |
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NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
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G |
MTUS1 |
microtubule associated scaffold protein 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MTUS1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094
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G |
MUC1 |
mucin 1, cell surface associated |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MUC1 affects the expression of EGFR protein] |
CTD |
PMID:22457794 |
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NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
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G |
MUC5AC |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein] |
CTD |
PMID:22766066 |
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NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
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G |
MYBPC3 |
myosin binding protein C3 |
decreases expression affects response to substance multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPC3 mRNA MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of BOK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CAV1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDH3 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CKB mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of EGFL7 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of FAHD1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of G0S2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of GPR146 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC12 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC13 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC15 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC22 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC7 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HAGHL mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HOPX mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KBTBD11 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LGALS1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC75A mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MCM5 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYL12B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYLK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of NRM mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PBK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PDLIM4 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLEKHG2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPARGC1B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPP1R3G mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ROBO4 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of SYNPO mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176A mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TRIB2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ZFYVE21 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of EIF2AK2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of FAM13B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of GADD45G mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of HSPA8 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of LUC7L mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of NRIP3 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SF1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SWT1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of UFD1 mRNA; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSS1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of C1QB mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHRM2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CLIP4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CMYA5 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXO10 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSG1L mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H2-AB1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HES1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KLHL6 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LDB3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LMO7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPC3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PIP5K1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLAC8 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SH3KBP1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPON2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UNC13C mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ZBTB8B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNMT3L mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of INSL6 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MT3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDPN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SPRR2G mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SYBU mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
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G |
MYBPHL |
myosin binding protein H like |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:109,292,365...109,307,011
Ensembl chr 1:109,292,365...109,307,011
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G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of MYC protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in increased degradation of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in decreased expression of MYC protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein [arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of MYC protein; [arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of MYC protein modified form; arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein]; FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]; NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]] |
CTD |
PMID:20046830 PMID:20945414 PMID:21472727 PMID:23593480 PMID:24457827 PMID:24793789 PMID:25897075 PMID:28548306 More...
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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G |
MYH6 |
myosin heavy chain 6 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYH6 mRNA |
CTD |
PMID:25566086 |
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NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
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G |
MYL1 |
myosin light chain 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174
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G |
MYL12B |
myosin light chain 12B |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYL12B mRNA |
CTD |
PMID:25566086 |
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NCBI chr18:3,262,133...3,278,461
Ensembl chr18:3,261,479...3,278,461
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G |
MYL7 |
myosin light chain 7 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:44,138,864...44,141,332
Ensembl chr 7:44,138,864...44,141,332
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G |
MYLK |
myosin light chain kinase |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYLK mRNA |
CTD |
PMID:25566086 |
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NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
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G |
MYLK3 |
myosin light chain kinase 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYLK3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:46,702,282...46,763,246
Ensembl chr16:46,702,282...46,790,407
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G |
MYO5B |
myosin VB |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA] |
CTD |
PMID:25566086 |
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NCBI chr18:49,822,789...50,195,147
Ensembl chr18:49,822,789...50,195,164
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G |
MYZAP |
myocardial zonula adherens protein |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA] |
CTD |
PMID:25566086 |
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NCBI chr15:57,591,904...57,685,364
Ensembl chr15:57,591,904...57,685,364
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G |
NACAD |
NAC alpha domain containing |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:45,080,437...45,088,969
Ensembl chr 7:45,080,437...45,088,969
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G |
NANOG |
Nanog homeobox |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of NANOG protein] |
CTD |
PMID:23651583 |
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NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
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G |
NAPB |
NSF attachment protein beta |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NAPB mRNA |
CTD |
PMID:25566086 |
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NCBI chr20:23,374,522...23,421,488
Ensembl chr20:23,374,519...23,421,519
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G |
NCOA3 |
nuclear receptor coactivator 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased degradation of NCOA3 protein] |
CTD |
PMID:16456540 |
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NCBI chr20:47,501,887...47,656,872
Ensembl chr20:47,501,887...47,656,877
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G |
NCOR1 |
nuclear receptor corepressor 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of NCOR1 protein |
CTD |
PMID:15857753 |
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NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185
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G |
NCOR2 |
nuclear receptor corepressor 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of NCOR2 protein |
CTD |
PMID:15857753 |
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NCBI chr12:124,324,415...124,567,612
Ensembl chr12:124,324,415...124,567,612
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G |
NDFIP1 |
Nedd4 family interacting protein 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] |
CTD |
PMID:26300475 |
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NCBI chr 5:142,108,779...142,154,440
Ensembl chr 5:142,108,779...142,154,440
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G |
NEDD4L |
NEDD4 like E3 ubiquitin protein ligase |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NEDD4L mRNA |
CTD |
PMID:20061341 |
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NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
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G |
NEURL2 |
neuralized E3 ubiquitin protein ligase 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NEURL2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr20:45,888,634...45,891,208
Ensembl chr20:45,888,625...45,891,208
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G |
NFAT5 |
nuclear factor of activated T cells 5 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased degradation of NFAT5 protein] |
CTD |
PMID:17105721 |
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NCBI chr16:69,565,966...69,704,654
Ensembl chr16:69,565,094...69,704,666
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G |
NFE2L1 |
NFE2 like bZIP transcription factor 1 |
decreases degradation multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NFE2L1 protein alternative form benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Glucose results in increased expression of NFE2L1 protein]; Glucose promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L1 protein]; Metformin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L1 protein] |
CTD |
PMID:28549828 PMID:33838154 |
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NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions decreases expression increases ubiquitination decreases degradation increases expression increases activity |
EXP ISO |
2-tert-butyl-4-quinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of and affects the localization of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Homocysteine results in decreased phosphorylation of and results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Glucose results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforaphane results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased stability of and results in increased ubiquitination of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of and results in increased activity of NFE2L2 protein; Curcumin inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]]; cyanoginosin LR inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; Metformin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC mRNA]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA]; quinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NFE2L2 protein modified form benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NFE2L2 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [N-acetylsphingosine results in decreased localization of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforaphane results in increased activity of NFE2L2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of NFE2L2 protein [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of and results in increased ubiquitination of NFE2L2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Cycloheximide] results in increased expression of NFE2L2 protein; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride affects the ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of NFE2L2 protein; Exenatide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein] [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein] which results in increased expression of CBR3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein |
CTD |
PMID:12441344 PMID:12446695 PMID:14510636 PMID:15319326 PMID:15322212 PMID:18512965 PMID:18550526 PMID:19786557 PMID:20722399 PMID:20806931 PMID:22019695 PMID:22558124 PMID:22606287 PMID:22964297 PMID:25263748 PMID:26598004 PMID:27939242 PMID:28645578 PMID:29618784 PMID:30186748 PMID:30703377 PMID:30926361 PMID:31319135 PMID:31806706 PMID:33434570 PMID:33838154 PMID:34758851 PMID:35478295 PMID:38016618 More...
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of [NFKB1 protein binds to RELA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein]; FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]; NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]] |
CTD |
PMID:11543732 PMID:14527959 PMID:14581482 PMID:16026644 PMID:24457827 |
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NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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G |
NFKBIA |
NFKB inhibitor alpha |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with TNF protein] results in increased phosphorylation of NFKBIA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [osthol results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Deoxycholic Acid results in increased phosphorylation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased degradation of NFKBIA protein; MAP1LC3B protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of NFKBIA protein]; sodium arsenite inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein] MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFKBIA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased phosphorylation of NFKBIA protein] |
CTD RGD |
PMID:11543732 PMID:11698246 PMID:11835394 PMID:11923223 PMID:12185005 PMID:12628480 PMID:12721113 PMID:12883408 PMID:15477007 PMID:16421291 PMID:17644113 PMID:20005289 PMID:22503731 PMID:23423712 PMID:24085292 PMID:25780039 PMID:22079846 More...
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RGD:401794136 |
NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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G |
NFKBIB |
NFKB inhibitor beta |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] |
CTD |
PMID:11543732 |
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NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893
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G |
NFKBIE |
NFKB inhibitor epsilon |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIE protein] |
CTD |
PMID:12185005 |
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NCBI chr 6:44,258,166...44,265,551
Ensembl chr 6:44,258,166...44,265,788
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G |
NGF |
nerve growth factor |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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G |
NGLY1 |
N-glycanase 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NGLY1 protein binds to UBXN1 protein] |
CTD |
PMID:15362974 |
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NCBI chr 3:25,718,944...25,790,039
Ensembl chr 3:25,718,944...25,790,039
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G |
NIPSNAP2 |
nipsnap homolog 2 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:55,964,585...56,000,179
Ensembl chr 7:55,951,793...56,000,181
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G |
NME3 |
NME/NM23 nucleoside diphosphate kinase 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NME3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:1,770,320...1,771,543
Ensembl chr16:1,770,320...1,771,561
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G |
NMRK2 |
nicotinamide riboside kinase 2 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr19:3,933,069...3,942,416
Ensembl chr19:3,933,069...3,942,416
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G |
NOL3 |
nucleolar protein 3 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [Doxorubicin results in increased degradation of NOL3 protein] |
CTD |
PMID:19139834 |
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NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737
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G |
NOS2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of NOS2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NOS2 protein |
CTD |
PMID:11923223 PMID:12628480 PMID:12721113 PMID:17891158 PMID:19376148 PMID:19393675 PMID:20675566 PMID:23395999 More...
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NOS3 |
nitric oxide synthase 3 |
decreases degradation increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NOS3 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOS3 protein |
CTD |
PMID:20229525 PMID:20675566 |
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NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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G |
NOTCH1 |
notch receptor 1 |
increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOTCH1 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptonide results in increased degradation of NOTCH1 protein] |
CTD |
PMID:24497960 PMID:24801890 PMID:31597699 PMID:31866380 |
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NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NQO1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NQO1 protein [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of NQO1 mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of NQO1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to NQO1 promoter] |
CTD |
PMID:16243960 PMID:20061341 PMID:22606287 PMID:30186748 PMID:33434570 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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G |
NR1I3 |
nuclear receptor subfamily 1 group I member 3 |
multiple interactions increases ubiquitination decreases activity increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [DNAJC7 protein results in increased expression of NR1I3 protein]; NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NR1I3 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of NR1I3 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in increased activity of NR1I3 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [GRIP1 protein binds to NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NR1I3 protein |
CTD |
PMID:24224465 PMID:24789201 |
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NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
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G |
NR3C1 |
nuclear receptor subfamily 3 group C member 1 |
multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NR3C1 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tubacin results in decreased expression of and results in increased degradation of NR3C1 mRNA] |
CTD |
PMID:20619282 PMID:31778773 PMID:31806706 |
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NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
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G |
NRG1 |
neuregulin 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KU-32 compound inhibits the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein] |
CTD |
PMID:23240583 |
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NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
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G |
NRIP3 |
nuclear receptor interacting protein 3 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of NRIP3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr11:8,980,576...9,004,505
Ensembl chr11:8,965,682...9,005,288
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G |
NRM |
nurim |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of NRM mRNA |
CTD |
PMID:25566086 |
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NCBI chr 6:30,688,049...30,691,420
Ensembl chr 6:30,688,047...30,691,420
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G |
NSD2 |
nuclear receptor binding SET domain protein 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3-deazaneplanocin results in increased degradation of NSD2 protein] |
CTD |
PMID:32001260 |
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NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207
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G |
NUF2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NUF2 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764
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G |
NUPR1 |
nuclear protein 1, transcriptional regulator |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NUPR1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008
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G |
OGG1 |
8-oxoguanine DNA glycosylase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TH5487 inhibits the reaction [TGFB1 protein results in increased expression of OGG1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [TGFB1 protein results in increased expression of OGG1 protein] |
CTD |
PMID:35654123 |
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NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
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G |
OPA1 |
OPA1 mitochondrial dynamin like GTPase |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of OPA1 protein alternative form |
CTD |
PMID:20678484 |
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NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
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G |
OPRD1 |
opioid receptor delta 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]] |
CTD |
PMID:21600884 |
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NCBI chr 1:28,812,170...28,871,267
Ensembl chr 1:28,812,170...28,871,267
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G |
OSGIN1 |
oxidative stress induced growth inhibitor 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of OSGIN1 mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
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G |
P2RX6 |
purinergic receptor P2X 6 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of P2RX6 mRNA |
CTD |
PMID:20061341 |
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NCBI chr22:21,009,799...21,028,008
Ensembl chr22:21,009,808...21,028,013
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G |
PARK7 |
Parkinsonism associated deglycase |
multiple interactions decreases response to substance |
ISO EXP |
PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Paraquat results in increased sulfation of and results in increased oxidation of PARK7 protein] PARK7 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde |
CTD |
PMID:18331584 PMID:26409479 |
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NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
increases cleavage |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein |
CTD |
PMID:15498850 PMID:16051428 PMID:18790767 PMID:20100472 PMID:34418242 |
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PAX2 |
paired box 2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PAX2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
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G |
PBK |
PDZ binding kinase |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PBK mRNA |
CTD |
PMID:25566086 |
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NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
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G |
PCDH7 |
protocadherin 7 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 4:30,720,369...31,146,800
Ensembl chr 4:30,720,369...31,146,805
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G |
PDCD6IP |
programmed cell death 6 interacting protein |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDCD6IP protein |
CTD |
PMID:21692457 |
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NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707
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G |
PDGFB |
platelet derived growth factor subunit B |
multiple interactions decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDGFB mRNA |
CTD |
PMID:15728660 PMID:25566086 |
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NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
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G |
PDK1 |
pyruvate dehydrogenase kinase 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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G |
PDLIM4 |
PDZ and LIM domain 4 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PDLIM4 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:132,257,696...132,273,454
Ensembl chr 5:132,257,696...132,273,454
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G |
PDLIM5 |
PDZ and LIM domain 5 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227
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G |
PDPN |
podoplanin |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDPN mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
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G |
PDXP |
pyridoxal phosphatase |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDXP mRNA |
CTD |
PMID:25566086 |
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NCBI chr22:37,658,723...37,666,932
Ensembl chr22:37,658,723...37,666,932
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G |
PDYN |
prodynorphin |
decreases secretion |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased secretion of PDYN protein alternative form |
CTD |
PMID:17670969 |
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NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285
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G |
PERM1 |
PPARGC1 and ESRR induced regulator, muscle 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:975,198...982,093
Ensembl chr 1:975,198...982,117
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G |
PFKFB3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PFKFB3 protein |
CTD |
PMID:19448625 |
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NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644
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G |
PFKP |
phosphofructokinase, platelet |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA] |
CTD |
PMID:25566086 |
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NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718
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G |
PGR |
progesterone receptor |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PGR protein |
CTD |
PMID:15218360 |
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NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
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G |
PIN1 |
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of PIN1 protein] |
CTD |
PMID:30093655 |
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NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689
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G |
PINK1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[ponasterone A results in increased expression of PINK1 protein] which results in decreased expression of FIS1 protein] |
CTD |
PMID:20164189 |
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NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
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G |
PIP5K1B |
phosphatidylinositol-4-phosphate 5-kinase type 1 beta |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PIP5K1B mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176
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G |
PKD1 |
polycystin 1, transient receptor potential channel interacting |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]] |
CTD |
PMID:25877301 |
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NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
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G |
PKIG |
cAMP-dependent protein kinase inhibitor gamma |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PKIG mRNA |
CTD |
PMID:25566086 |
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NCBI chr20:44,531,875...44,619,037
Ensembl chr20:44,531,785...44,624,247
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G |
PLAC8 |
placenta associated 8 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLAC8 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,090,048...83,137,075
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G |
PLEKHA6 |
pleckstrin homology domain containing A6 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLEKHA6 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:204,218,853...204,378,168
Ensembl chr 1:204,218,853...204,378,214
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G |
PLEKHG2 |
pleckstrin homology and RhoGEF domain containing G2 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLEKHG2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr19:39,412,669...39,428,415
Ensembl chr19:39,412,669...39,428,415
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G |
PLK1 |
polo like kinase 1 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLK1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367
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G |
PLN |
phospholamban |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLN mRNA |
CTD |
PMID:25566086 |
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NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
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G |
PLOD3 |
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLOD3 protein |
CTD |
PMID:21692457 |
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NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
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G |
PLVAP |
plasmalemma vesicle associated protein |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLVAP mRNA |
CTD |
PMID:25566086 |
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NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,342
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G |
PMAIP1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
decreases degradation increases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PMAIP1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]; MAPK9 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] |
CTD |
PMID:20802529 PMID:23593480 PMID:31806706 |
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NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
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G |
PML |
PML nuclear body scaffold |
decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PML protein modified form |
CTD |
PMID:26049103 |
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NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
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G |
PNPLA3 |
patatin like phospholipase domain containing 3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PNPLA3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488
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G |
POU5F1 |
POU class 5 homeobox 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of POU5F1 protein |
CTD |
PMID:24497960 |
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NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
increases activity multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of PPARG protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of PPARG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [rosiglitazone results in decreased expression of PPARG protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [alitretinoin results in increased activity of PPARG protein] |
CTD |
PMID:15707588 PMID:18555852 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PPARGC1A |
PPARG coactivator 1 alpha |
decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PPARGC1A protein |
CTD |
PMID:20860658 |
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NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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G |
PPARGC1B |
PPARG coactivator 1 beta |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPARGC1B mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
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G |
PPIA |
peptidylprolyl isomerase A |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPIA mRNA |
CTD |
PMID:15857753 |
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NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564
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G |
PPL |
periplakin |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PPL mRNA |
CTD |
PMID:20061341 |
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NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741
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G |
PPP1R14C |
protein phosphatase 1 regulatory inhibitor subunit 14C |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 6:150,143,044...150,250,392
Ensembl chr 6:150,143,044...150,250,392
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G |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
increases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PPP1R15A mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein] |
CTD |
PMID:19135031 PMID:25566086 PMID:29109149 |
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NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
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G |
PPP1R3G |
protein phosphatase 1 regulatory subunit 3G |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPP1R3G mRNA |
CTD |
PMID:25566086 |
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NCBI chr 6:5,085,341...5,089,487
Ensembl chr 6:5,085,341...5,089,487
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G |
PRC1 |
protein regulator of cytokinesis 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629
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G |
PRDX1 |
peroxiredoxin 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PRDX1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
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G |
PRKCB |
protein kinase C beta |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] |
CTD |
PMID:17644113 |
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NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
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G |
PRKCD |
protein kinase C delta |
multiple interactions increases phosphorylation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NSC606985 results in increased activity of and results in increased cleavage of PRKCD protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [PRKCD protein results in increased ubiquitination of HNRNPK protein]; Glutathione inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of PRKCD protein] |
CTD |
PMID:15707588 PMID:19662097 PMID:19747914 |
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NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
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G |
PRKCSH |
PRKCSH beta subunit of glucosidase II |
increases response to substance |
ISO |
PRKCSH gene mutant form results in increased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde |
CTD |
PMID:21685914 |
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NCBI chr19:11,435,635...11,450,968
Ensembl chr19:11,435,284...11,450,968
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G |
PRKN |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions affects expression decreases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [PRKN protein results in decreased expression of SLC11A2 protein alternative form]; Tretinoin affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of PRKN protein alternative form] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN mRNA |
CTD |
PMID:18586549 PMID:20089134 PMID:28673964 PMID:28688199 |
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NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
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G |
PSEN1 |
presenilin 1 |
multiple interactions |
EXP |
[PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein] |
CTD |
PMID:22302987 |
|
NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691
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G |
PSMA1 |
proteasome 20S subunit alpha 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA1 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr11:14,504,876...14,643,662
Ensembl chr11:14,504,874...14,643,635
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G |
PSMA2 |
proteasome 20S subunit alpha 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA2 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr 7:42,916,861...42,932,174
Ensembl chr 7:42,916,828...42,932,185
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G |
PSMA3 |
proteasome 20S subunit alpha 3 |
increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA3 mRNA |
CTD |
PMID:15525353 PMID:31806706 |
|
NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012
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G |
PSMA4 |
proteasome 20S subunit alpha 4 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA4 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr15:78,540,405...78,552,417
Ensembl chr15:78,540,405...78,552,417
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G |
PSMA5 |
proteasome 20S subunit alpha 5 |
increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA5 mRNA |
CTD |
PMID:15525353 PMID:31806706 |
|
NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448
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G |
PSMA6 |
proteasome 20S subunit alpha 6 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA6 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr14:35,278,558...35,317,493
Ensembl chr14:35,278,633...35,317,493
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G |
PSMA7 |
proteasome 20S subunit alpha 7 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA7 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr20:62,136,733...62,143,394
Ensembl chr20:62,136,733...62,143,440
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G |
PSMB10 |
proteasome 20S subunit beta 10 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB10 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr16:67,934,506...67,936,850
Ensembl chr16:67,934,506...67,936,864
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G |
PSMB2 |
proteasome 20S subunit beta 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB2 mRNA |
CTD |
PMID:31806706 |
|
NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
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G |
PSMB3 |
proteasome 20S subunit beta 3 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB3 mRNA |
CTD |
PMID:31806706 |
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NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225
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G |
PSMB4 |
proteasome 20S subunit beta 4 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB4 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937
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G |
PSMB5 |
proteasome 20S subunit beta 5 |
increases expression multiple interactions decreases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB5 mRNA [sodium arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of PSMB5 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased expression of PSMB5 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in decreased expression of PSMB5 protein]; sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB5 mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB5 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB5 protein |
CTD |
PMID:15525353 PMID:31806706 PMID:32301004 |
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NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230
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G |
PSMB6 |
proteasome 20S subunit beta 6 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB6 mRNA |
CTD |
PMID:31806706 |
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NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502
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G |
PSMB7 |
proteasome 20S subunit beta 7 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB7 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444
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G |
PSMB9 |
proteasome 20S subunit beta 9 |
decreases expression increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB9 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB9 mRNA |
CTD |
PMID:20061341 PMID:31806706 |
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NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
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G |
PSMC1 |
proteasome 26S subunit, ATPase 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
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G |
PSMC2 |
proteasome 26S subunit, ATPase 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC2 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346
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G |
PSMC3 |
proteasome 26S subunit, ATPase 3 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC3 mRNA |
CTD |
PMID:31806706 |
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NCBI chr11:47,418,775...47,426,439
Ensembl chr11:47,418,769...47,426,473
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G |
PSMC4 |
proteasome 26S subunit, ATPase 4 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC4 mRNA |
CTD |
PMID:31806706 |
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NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764
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G |
PSMC5 |
proteasome 26S subunit, ATPase 5 |
multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction and affects the localization of [PSMC5 protein binds to GABBR2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC5 mRNA |
CTD |
PMID:24482233 PMID:31806706 |
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NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026
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G |
PSMC6 |
proteasome 26S subunit, ATPase 6 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC6 mRNA |
CTD |
PMID:31806706 |
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NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590
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G |
PSMD1 |
proteasome 26S subunit, non-ATPase 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,845...231,173,116
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G |
PSMD11 |
proteasome 26S subunit, non-ATPase 11 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD11 mRNA |
CTD |
PMID:31806706 |
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NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319
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G |
PSMD12 |
proteasome 26S subunit, non-ATPase 12 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD12 mRNA |
CTD |
PMID:31806706 |
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NCBI chr17:67,337,916...67,366,577
Ensembl chr17:67,337,916...67,366,605
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G |
PSMD13 |
proteasome 26S subunit, non-ATPase 13 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD13 mRNA |
CTD |
PMID:31806706 |
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NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984
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G |
PSMD14 |
proteasome 26S subunit, non-ATPase 14 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD14 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717
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G |
PSMD2 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD2 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050
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G |
PSMD3 |
proteasome 26S subunit, non-ATPase 3 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD3 mRNA |
CTD |
PMID:31806706 |
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NCBI chr17:39,980,807...39,997,959
Ensembl chr17:39,980,807...39,997,959
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G |
PSMD4 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 4 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] |
CTD |
PMID:15362974 |
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NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,709...151,267,479
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G |
PSMD6 |
proteasome 26S subunit, non-ATPase 6 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD6 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010
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G |
PSMD8 |
proteasome 26S subunit, non-ATPase 8 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD8 mRNA |
CTD |
PMID:31806706 |
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NCBI chr19:38,374,571...38,383,824
Ensembl chr19:38,374,563...38,383,850
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G |
PSME1 |
proteasome activator subunit 1 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSME1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967
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G |
PSME2 |
proteasome activator subunit 2 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSME2 mRNA |
CTD |
PMID:31806706 |
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NCBI chr14:24,143,365...24,146,610
Ensembl chr14:24,143,362...24,147,570
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G |
PSME4 |
proteasome activator subunit 4 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSME4 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 2:53,864,069...53,970,993
Ensembl chr 2:53,864,069...53,970,993
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G |
PTEN |
phosphatase and tensin homolog |
multiple interactions increases ubiquitination increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc Sulfate results in decreased stability of PTEN protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of PTEN protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of PTEN protein modified form benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTEN protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein] |
CTD |
PMID:17684018 PMID:20100827 PMID:24449419 PMID:33256086 |
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NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
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G |
PTGER1 |
prostaglandin E receptor 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein] |
CTD |
PMID:20335389 |
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NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
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G |
PTGES3 |
prostaglandin E synthase 3 |
decreases degradation multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PTGES3 protein 4-tosylcyclonovobiocic acid promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PTGES3 protein] |
CTD |
PMID:19118525 |
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NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of PTGS2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of PTGS2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTGS2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTGS2 protein |
CTD |
PMID:11230753 PMID:12628480 PMID:12721113 PMID:17084486 PMID:18457675 PMID:22767315 PMID:24085292 More...
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTK2B |
protein tyrosine kinase 2 beta |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [PTK2B protein affects the ubiquitination of ESR1 protein] |
CTD |
PMID:29428397 |
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NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391
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G |
PTP4A3 |
protein tyrosine phosphatase 4A3 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PTP4A3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 8:141,392,021...141,432,454
Ensembl chr 8:141,391,995...141,432,454
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G |
PTPN1 |
protein tyrosine phosphatase non-receptor type 1 |
multiple interactions |
EXP |
PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:28359145 |
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NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
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G |
RAB33A |
RAB33A, member RAS oncogene family |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RAB33A mRNA |
CTD |
PMID:25566086 |
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NCBI chr X:130,110,623...130,184,870
Ensembl chr X:130,171,962...130,184,870
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G |
RABL6 |
RAB, member RAS oncogene family like 6 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RABL6 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 9:136,807,948...136,841,187
Ensembl chr 9:136,807,943...136,841,187
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G |
RAD51 |
RAD51 recombinase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] |
CTD |
PMID:21810436 |
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NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
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G |
RAF1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein] |
CTD |
PMID:27794399 |
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NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
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G |
RAMP1 |
receptor activity modifying protein 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RAMP1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 2:237,858,880...237,912,106
Ensembl chr 2:237,858,893...237,912,106
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G |
RARA |
retinoic acid receptor alpha |
increases ubiquitination multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RARA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased degradation of RARA protein] |
CTD |
PMID:20945414 PMID:24819975 |
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NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
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G |
RARRES2 |
retinoic acid receptor responder 2 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662
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G |
RASSF5 |
Ras association domain family member 5 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RASSF5 protein results in decreased expression of CTNNB1 protein] |
CTD |
PMID:25217643 |
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NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448
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G |
RBL1 |
RB transcriptional corepressor like 1 |
increases expression increases ubiquitination multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBL1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RBL1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [palbociclib results in decreased expression of RBL1 protein]; palbociclib promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RBL1 protein] |
CTD |
PMID:20100483 |
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NCBI chr20:36,996,349...37,095,997
Ensembl chr20:36,996,349...37,095,997
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G |
RBP3 |
retinol binding protein 3 |
decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of RBP3 protein mutant form |
CTD |
PMID:23486466 |
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NCBI chr10:47,348,363...47,357,881
Ensembl chr10:47,348,363...47,357,881
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G |
RBPJ |
recombination signal binding protein for immunoglobulin kappa J region |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein] |
CTD |
PMID:22302987 |
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NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131
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G |
RCN2 |
reticulocalbin 2 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RCN2 protein |
CTD |
PMID:21692457 |
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NCBI chr15:76,931,749...76,954,393
Ensembl chr15:76,931,738...76,954,393
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G |
RELA |
RELA proto-oncogene, NF-kB subunit |
increases activity decreases expression increases ubiquitination multiple interactions affects localization decreases activity |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein MG132 pretreatment decreases expression of protein in liver of intestinal ischemia/reperfusion rats benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RELA protein Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cisplatin promotes the reaction [RELA protein binds to TP63 protein alternative form]] which results in increased degradation of TP63 protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CIGB-552 peptide results in decreased expression of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trimethyltin chloride affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of [NFKB1 protein binds to RELA protein]; SB 203580 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of RELA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan affects the localization of RELA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [halofuginone affects the localization of RELA protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of RELA protein |
CTD RGD |
PMID:11543732 PMID:12628480 PMID:12721113 PMID:14527959 PMID:14581482 PMID:15498850 PMID:16026644 PMID:16489207 PMID:17644113 PMID:18457675 PMID:21088498 PMID:22766066 PMID:23401744 PMID:23423712 PMID:23686307 PMID:22079846 More...
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RGD:401794136 |
NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
RGMA |
repulsive guidance molecule BMP co-receptor a |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RGMA mRNA |
CTD |
PMID:25566086 |
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NCBI chr15:93,035,271...93,089,211
Ensembl chr15:93,035,271...93,089,211
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G |
RHOB |
ras homolog family member B |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SMURF1 protein results in increased degradation of RHOB protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of RHOB protein] |
CTD |
PMID:30587574 PMID:31140275 |
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NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
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G |
RHOC |
ras homolog family member C |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF168 protein results in decreased expression of RHOC protein] |
CTD |
PMID:34873829 |
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NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434
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G |
RICTOR |
RPTOR independent companion of MTOR complex 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased ubiquitination of RICTOR protein |
CTD |
PMID:25897075 |
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NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402
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G |
RNF144B |
ring finger protein 144B |
multiple interactions decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile results in increased degradation of RNF144B protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of RNF144B protein |
CTD |
PMID:29724995 |
|
NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
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G |
RNF168 |
ring finger protein 168 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF168 protein results in decreased expression of RHOC protein] |
CTD |
PMID:34873829 |
|
NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768
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G |
RNF187 |
ring finger protein 187 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ro 31-8220 results in decreased stability of RNF187 protein] |
CTD |
PMID:25851810 |
|
NCBI chr 1:228,487,382...228,496,188
Ensembl chr 1:228,487,382...228,499,899
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G |
RNF208 |
ring finger protein 208 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RNF208 mRNA |
CTD |
PMID:25566086 |
|
NCBI chr 9:137,220,259...137,223,408
Ensembl chr 9:137,220,247...137,222,240
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G |
RNF31 |
ring finger protein 31 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF31 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNFAIP3 protein]] |
CTD |
PMID:34416243 |
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NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660
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G |
ROBO4 |
roundabout guidance receptor 4 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ROBO4 mRNA |
CTD |
PMID:25566086 |
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NCBI chr11:124,883,691...124,897,865
Ensembl chr11:124,883,691...124,898,500
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G |
RPS6KB1 |
ribosomal protein S6 kinase B1 |
multiple interactions decreases phosphorylation |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]] Sirolimus promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:22689575 PMID:31645432 |
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NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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G |
RPTOR |
regulatory associated protein of MTOR complex 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RPTOR protein |
CTD |
PMID:25897075 |
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NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371
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G |
RRM2 |
ribonucleotide reductase regulatory subunit M2 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA |
CTD |
PMID:25566086 |
|
NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
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G |
RXRA |
retinoid X receptor alpha |
multiple interactions increases expression |
EXP |
[Alitretinoin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of RXRA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Alitretinoin results in increased degradation of RXRA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of RXRA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RXRA protein |
CTD |
PMID:12970875 PMID:15707588 PMID:17170071 PMID:22310326 |
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NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
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G |
SAE1 |
SUMO1 activating enzyme subunit 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SAE1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr19:47,130,835...47,210,636
Ensembl chr19:47,113,274...47,210,636
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G |
SCARB1 |
scavenger receptor class B member 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of SCARB1 protein] |
CTD |
PMID:22442701 |
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NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
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G |
SELENBP1 |
selenium binding protein 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SELENBP1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707
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G |
SESN2 |
sestrin 2 |
multiple interactions increases ubiquitination increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein]; Lipopolysaccharides inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of SESN2 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SESN2 protein |
CTD |
PMID:25637945 |
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NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491
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G |
SET |
SET nuclear proto-oncogene |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SET protein |
CTD |
PMID:21692457 |
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NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400
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G |
SF1 |
splicing factor 1 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SF1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr11:64,764,606...64,778,542
Ensembl chr11:64,764,606...64,778,786
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G |
SH3KBP1 |
SH3 domain containing kinase binding protein 1 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SH3KBP1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr X:19,533,977...19,887,600
Ensembl chr X:19,533,977...19,887,600
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G |
SIAH2 |
siah E3 ubiquitin protein ligase 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SIAH2 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
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G |
SIRT1 |
sirtuin 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein] |
CTD |
PMID:25440059 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SIRT6 |
sirtuin 6 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SIRT6 protein results in decreased expression of EP300 protein] |
CTD |
PMID:27094368 |
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NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566
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G |
SKP1 |
S-phase kinase associated protein 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 5:134,148,935...134,176,950
Ensembl chr 5:134,148,935...134,176,964
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G |
SKP2 |
S-phase kinase associated protein 2 |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP2 mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SKP2 protein results in decreased expression of DUSP1 protein] |
CTD |
PMID:20061341 PMID:34697729 |
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NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849
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G |
SLBP |
stem-loop histone mRNA binding protein |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of SLBP protein] |
CTD |
PMID:25266719 |
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NCBI chr 4:1,692,731...1,712,319
Ensembl chr 4:1,692,731...1,712,344
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G |
SLC10A2 |
solute carrier family 10 member 2 |
increases expression multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC10A2 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of SLC10A2 protein] |
CTD |
PMID:23872411 PMID:24498857 |
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NCBI chr13:103,043,998...103,066,417
Ensembl chr13:103,043,998...103,066,417
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G |
SLC11A2 |
solute carrier family 11 member 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [PRKN protein results in decreased expression of SLC11A2 protein alternative form] |
CTD |
PMID:20089134 |
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NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
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G |
SLC29A1 |
solute carrier family 29 member 1 (Augustine blood group) |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC29A1 mRNA |
CTD |
PMID:31806706 |
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NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142
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G |
SLC2A1 |
solute carrier family 2 member 1 |
increases expression multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC2A1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of SLC2A1 protein] |
CTD |
PMID:17442736 PMID:31850806 PMID:32461003 |
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NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
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G |
SLC31A1 |
solute carrier family 31 member 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cisplatin results in increased degradation of SLC31A1 protein] |
CTD |
PMID:17108132 |
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NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492
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G |
SLC39A4 |
solute carrier family 39 member 4 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] |
CTD |
PMID:17202136 |
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NCBI chr 8:144,412,414...144,416,844
Ensembl chr 8:144,409,742...144,416,844
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G |
SLC6A3 |
solute carrier family 6 member 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] |
CTD |
PMID:26300475 |
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NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
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G |
SLC6A9 |
solute carrier family 6 member 9 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
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G |
SLC7A11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A11 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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G |
SLC7A3 |
solute carrier family 7 member 3 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A3 mRNA |
CTD |
PMID:25566086 |
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NCBI chr X:70,925,579...70,931,096
Ensembl chr X:70,925,579...70,931,125
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G |
SLCO1B1 |
solute carrier organic anion transporter family member 1B1 |
multiple interactions decreases degradation |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SLCO1B1 protein mutant form] which binds to and results in increased uptake of estrone sulfate |
CTD |
PMID:31254566 |
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NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796
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G |
SLN |
sarcolipin |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SLN mRNA |
CTD |
PMID:25566086 |
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NCBI chr11:107,707,378...107,712,056
Ensembl chr11:107,707,378...107,719,693
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G |
SMTNL2 |
smoothelin like 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SMTNL2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr17:4,584,007...4,608,319
Ensembl chr17:4,583,999...4,608,319
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G |
SMURF1 |
SMAD specific E3 ubiquitin protein ligase 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SMURF1 protein results in increased degradation of RHOB protein] |
CTD |
PMID:30587574 |
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NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108
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G |
SNCA |
synuclein alpha |
increases phosphorylation multiple interactions |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of SNCA protein [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of and results in increased ubiquitination of NFE2L2 protein; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein] |
CTD |
PMID:33157086 PMID:38016618 |
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NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
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G |
SNRK |
SNF related kinase |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr 3:43,286,540...43,351,143
Ensembl chr 3:43,286,512...43,424,764
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G |
SOAT2 |
sterol O-acyltransferase 2 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SOAT2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr12:53,103,486...53,124,535
Ensembl chr12:53,103,486...53,124,535
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G |
SOCS3 |
suppressor of cytokine signaling 3 |
decreases degradation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SOCS3 protein |
CTD |
PMID:23782265 |
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NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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G |
SOD1 |
superoxide dismutase 1 |
multiple interactions decreases expression increases expression |
EXP ISO |
[sodium arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of SOD1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC2 protein results in increased degradation of SOD1 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC3 protein results in increased degradation of SOD1 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of SOD1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of SOD1 mRNA]; sodium arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SOD1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SOD1 mRNA |
CTD |
PMID:17309078 PMID:20061341 PMID:27773815 PMID:30503815 PMID:32301004 |
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein] |
CTD |
PMID:12161520 PMID:24973648 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SORT1 |
sortilin 1 |
multiple interactions decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tetrabromocinnamic acid results in increased degradation of SORT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [wortmannin results in increased degradation of SORT1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SORT1 protein |
CTD |
PMID:25805502 |
|
NCBI chr 1:109,309,575...109,397,918
Ensembl chr 1:109,309,568...109,397,918
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G |
SOX18 |
SRY-box transcription factor 18 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SOX18 mRNA |
CTD |
PMID:25566086 |
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NCBI chr20:64,047,582...64,049,639
Ensembl chr20:64,047,582...64,049,639
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G |
SOX9 |
SRY-box transcription factor 9 |
multiple interactions |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form] which results in increased expression of SOX9 mRNA |
CTD |
PMID:27576690 |
|
NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
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G |
SP1 |
Sp1 transcription factor |
multiple interactions |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [SP1 protein binds to ARNT promoter]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased activity of SP1 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione results in decreased expression of SP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Daunorubicin results in decreased expression of SP1 protein] |
CTD |
PMID:14529614 PMID:17409431 PMID:34963561 |
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NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
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G |
SP3 |
Sp3 transcription factor |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SP3 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SP3 protein |
CTD |
PMID:25068794 |
|
NCBI chr 2:173,900,775...173,965,702
Ensembl chr 2:173,880,850...173,965,373
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G |
SPON2 |
spondin 2 |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPON2 mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962
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G |
SPRR2G |
small proline rich protein 2G |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SPRR2G mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr 1:153,149,582...153,203,278
Ensembl chr 1:153,149,582...153,150,890
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G |
SPSB4 |
splA/ryanodine receptor domain and SOCS box containing 4 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA] |
CTD |
PMID:25566086 |
|
NCBI chr 3:141,051,347...141,148,611
Ensembl chr 3:141,051,347...141,148,611
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G |
SQSTM1 |
sequestosome 1 |
multiple interactions increases expression |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 protein [methylmercuric chloride co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of SQSTM1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [SQSTM1 protein affects the susceptibility to methylmercuric chloride]; methylmercuric chloride promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 mRNA] |
CTD |
PMID:27629431 PMID:37258240 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRC |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein] |
CTD |
PMID:24224465 PMID:27794399 |
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NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
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G |
SRL |
sarcalumenin |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SRL mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:4,189,374...4,242,080
Ensembl chr16:4,189,374...4,242,080
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G |
SRSF2 |
serine and arginine rich splicing factor 2 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KAT5 protein results in increased acetylation of and results in increased degradation of SRSF2 protein] |
CTD |
PMID:21157427 |
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NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333
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G |
SRXN1 |
sulfiredoxin 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRXN1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
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G |
SRY |
sex determining region Y |
decreases degradation increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRY protein modified form [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form] which results in increased expression of SOX9 mRNA; SRY protein mutant form promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRY protein modified form] |
CTD |
PMID:27576690 |
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NCBI chr Y:2,786,855...2,787,682
Ensembl chr Y:2,786,855...2,787,682
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G |
SSPN |
sarcospan |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA] |
CTD |
PMID:25566086 |
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NCBI chr12:26,121,991...26,234,777
Ensembl chr12:26,121,991...26,299,290
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G |
STAT1 |
signal transducer and activator of transcription 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of and results in increased phosphorylation of STAT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of STAT1 mRNA] |
CTD |
PMID:20945414 |
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NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
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G |
STAT6 |
signal transducer and activator of transcription 6 |
affects phosphorylation |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the phosphorylation of STAT6 protein |
CTD |
PMID:12459556 |
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NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
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G |
STK11 |
serine/threonine kinase 11 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of MYC protein]] |
CTD |
PMID:24793789 |
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NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
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G |
STRIP2 |
striatin interacting protein 2 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of STRIP2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:129,434,432...129,488,399
Ensembl chr 7:129,434,432...129,488,399
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G |
STS |
steroid sulfatase |
multiple interactions decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased activity of STS protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of STS mRNA |
CTD |
PMID:16178010 PMID:24055520 |
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NCBI chr X:7,147,290...7,354,641
Ensembl chr X:7,147,237...7,804,358
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G |
SUV39H1 |
SUV39H1 histone lysine methyltransferase |
multiple interactions |
EXP |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; [TNF protein co-treated with 6-formylindolo(3,2-b)carbazole co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with Sirolimus co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein] |
CTD |
PMID:31676321 |
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NCBI chr X:48,695,554...48,709,016
Ensembl chr X:48,695,554...48,709,016
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G |
SWT1 |
SWT1 RNA endoribonuclease homolog |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SWT1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:185,157,060...185,291,781
Ensembl chr 1:185,157,080...185,291,781
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G |
SYBU |
syntabulin |
multiple interactions increases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SYBU mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 8:109,573,978...109,691,600
Ensembl chr 8:109,573,978...109,691,791
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G |
SYNPO |
synaptopodin |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of SYNPO mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:150,586,010...150,659,207
Ensembl chr 5:150,601,080...150,659,207
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G |
SYP |
synaptophysin |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] |
CTD |
PMID:18487452 |
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NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218
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G |
TAF1 |
TATA-box binding protein associated factor 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione results in decreased expression of TAF1 protein] |
CTD |
PMID:17409431 |
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NCBI chr X:71,366,357...71,530,525
Ensembl chr X:71,366,136...71,532,374
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G |
TAF1A |
TATA-box binding protein associated factor, RNA polymerase I subunit A |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TAF1A mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:222,554,105...222,589,933
Ensembl chr 1:222,557,902...222,589,933
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G |
TARDBP |
TAR DNA binding protein |
affects localization increases ubiquitination |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of TARDBP protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TARDBP protein |
CTD |
PMID:19765185 PMID:31780563 |
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NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528
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G |
TDRP |
testis development related protein |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TDRP mRNA |
CTD |
PMID:25566086 |
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NCBI chr 8:489,946...545,780
Ensembl chr 8:489,803...545,781
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G |
TENM4 |
teneurin transmembrane protein 4 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr11:78,652,829...79,441,030
Ensembl chr11:78,652,829...79,441,030
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G |
TERT |
telomerase reverse transcriptase |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] |
CTD |
PMID:21520056 |
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NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
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G |
TESC |
tescalcin |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TESC mRNA |
CTD |
PMID:25566086 |
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NCBI chr12:117,038,923...117,099,416
Ensembl chr12:117,038,923...117,099,479
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G |
TFAM |
transcription factor A, mitochondrial |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of TFAM mRNA] |
CTD |
PMID:20860658 |
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NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
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G |
TFRC |
transferrin receptor |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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G |
TG |
thyroglobulin |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Amiodarone results in decreased expression of TG protein] |
CTD |
PMID:25295624 |
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NCBI chr 8:132,866,958...133,134,899
Ensembl chr 8:132,866,958...133,134,903
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G |
TGFB1 |
transforming growth factor beta 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TGFB1 protein results in decreased expression of LPIN1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TH5487 inhibits the reaction [TGFB1 protein results in increased expression of OGG1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [TGFB1 protein results in increased expression of OGG1 protein] |
CTD |
PMID:27345520 PMID:35654123 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TGFBI |
transforming growth factor beta induced |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TGFBI mRNA |
CTD |
PMID:25566086 |
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NCBI chr 5:136,028,988...136,063,818
Ensembl chr 5:136,028,988...136,063,818
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G |
TGFBR1 |
transforming growth factor beta receptor 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tolfenamic acid results in decreased expression of TGFBR1 protein] |
CTD |
PMID:31381904 |
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NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
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G |
THY1 |
Thy-1 cell surface antigen |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985
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G |
TIPARP |
TCDD inducible poly(ADP-ribose) polymerase |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] |
CTD |
PMID:12147270 |
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NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770
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G |
TK1 |
thymidine kinase 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TK1 mRNA [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TK1 mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233
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G |
TMEM176A |
transmembrane protein 176A |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176A mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:150,800,769...150,805,118
Ensembl chr 7:150,800,403...150,805,118
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G |
TMEM176B |
transmembrane protein 176B |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176B mRNA |
CTD |
PMID:25566086 |
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NCBI chr 7:150,791,301...150,801,360
Ensembl chr 7:150,791,285...150,801,360
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G |
TMEM204 |
transmembrane protein 204 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr16:1,528,678...1,555,568
Ensembl chr16:1,528,688...1,555,580
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G |
TMOD1 |
tropomodulin 1 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743
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G |
TMT1A |
thiol methyltransferase 1A |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMT1A mRNA |
CTD |
PMID:31806706 |
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NCBI chr12:50,925,015...50,932,508
Ensembl chr12:50,923,472...50,932,510
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G |
TNF |
tumor necrosis factor |
multiple interactions decreases expression |
EXP ISO |
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with TNF protein] results in increased phosphorylation of NFKBIA protein; [TNF protein co-treated with 6-formylindolo(3,2-b)carbazole co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with Sirolimus co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in increased expression of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CX3CL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of PTGS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of VEGFA protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein] MG132 pretreatment decreases expression of TNFa, IL6 protein in serum of intestinal ischemia/reperfusion rats benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNF mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]] benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of TNF mRNA] |
CTD RGD |
PMID:11230753 PMID:11698246 PMID:12185005 PMID:12628480 PMID:12883408 PMID:14572618 PMID:19393675 PMID:23288922 PMID:23395999 PMID:24085292 PMID:24613819 PMID:28134560 PMID:31676321 PMID:31806706 PMID:22079846 More...
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RGD:401794136 |
NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP1 |
TNF alpha induced protein 1 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNFAIP1 protein results in increased degradation of CSNK2B protein] |
CTD |
PMID:37302538 |
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NCBI chr17:28,335,761...28,347,009
Ensembl chr17:28,335,602...28,347,009
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G |
TNFAIP3 |
TNF alpha induced protein 3 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF31 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNFAIP3 protein]] |
CTD |
PMID:34416243 |
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NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
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G |
TNFAIP8L1 |
TNF alpha induced protein 8 like 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNFAIP8L1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr19:4,639,516...4,655,568
Ensembl chr19:4,639,516...4,655,568
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G |
TNFRSF10A |
TNF receptor superfamily member 10a |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TNFRSF10A protein |
CTD |
PMID:16287099 |
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NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
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G |
TNFRSF10B |
TNF receptor superfamily member 10b |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TNFRSF10B protein |
CTD |
PMID:16287099 PMID:17510429 |
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NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
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G |
TNNI1 |
troponin I1, slow skeletal type |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 1:201,403,784...201,421,730
Ensembl chr 1:201,403,784...201,429,866
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G |
TNNI2 |
troponin I2, fast skeletal type |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr11:1,838,981...1,841,678
Ensembl chr11:1,838,981...1,841,680
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G |
TNNI3 |
troponin I3, cardiac type |
multiple interactions decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in decreased expression of TNNI3 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI3 mRNA |
CTD |
PMID:19801490 PMID:25566086 |
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NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
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G |
TOP2A |
DNA topoisomerase II alpha |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] |
CTD |
PMID:17575151 |
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NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
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G |
TP53 |
tumor protein p53 |
multiple interactions increases expression increases ubiquitination |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chlorpyrifos results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of TP53 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein modified form benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TP53 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased expression of TP53 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein |
CTD |
PMID:10837373 PMID:16330492 PMID:18463101 PMID:18951928 PMID:19699254 PMID:20530418 PMID:21454520 PMID:26612707 PMID:27129209 PMID:27993609 PMID:31806706 PMID:35821281 More...
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
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G |
TP63 |
tumor protein p63 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cisplatin promotes the reaction [RELA protein binds to TP63 protein alternative form]] which results in increased degradation of TP63 protein alternative form] |
CTD |
PMID:21088498 |
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NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276
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G |
TRAF2 |
TNF receptor associated factor 2 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TRAF2 protein results in decreased expression of KLF2 protein] |
CTD |
PMID:35635602 |
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NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607
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G |
TRIB2 |
tribbles pseudokinase 2 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TRIB2 mRNA |
CTD |
PMID:25566086 |
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NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734
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G |
TRIB3 |
tribbles pseudokinase 3 |
decreases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIB3 mRNA |
CTD |
PMID:31806706 |
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NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
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G |
TRIL |
TLR4 interactor with leucine rich repeats |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330
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G |
TRIM72 |
tripartite motif containing 72 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIM72 mRNA |
CTD |
PMID:25566086 |
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NCBI chr16:31,214,119...31,231,537
Ensembl chr16:31,214,119...31,231,537
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G |
TSC22D3 |
TSC22 domain family member 3 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]] |
CTD |
PMID:20671745 |
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NCBI chr X:107,713,221...107,775,988
Ensembl chr X:107,713,221...107,777,342
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G |
TSC22D4 |
TSC22 domain family member 4 |
decreases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 7:100,466,519...100,479,214
Ensembl chr 7:100,463,359...100,479,232
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G |
TXNL1 |
thioredoxin like 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in increased degradation of TXNL1 protein] |
CTD |
PMID:19349280 |
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NCBI chr18:56,597,209...56,638,592
Ensembl chr18:56,597,209...56,651,600
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G |
TXNRD1 |
thioredoxin reductase 1 |
increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TXNRD1 mRNA |
CTD |
PMID:18550526 |
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NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
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G |
TYMP |
thymidine phosphorylase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]] |
CTD |
PMID:21444628 PMID:30796972 |
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NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
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G |
TYMS |
thymidylate synthetase |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cinobufagin results in decreased expression of TYMS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of TYMS protein] |
CTD |
PMID:17172411 PMID:21444628 PMID:35427566 |
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NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
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G |
TYR |
tyrosinase |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein] |
CTD |
PMID:23872139 |
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NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759
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G |
UBB |
ubiquitin B |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[PARK protein co-treated with UBB protein] results in decreased expression of FIS1 protein] |
CTD |
PMID:20164189 |
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NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
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G |
UBC |
ubiquitin C |
multiple interactions increases expression |
EXP ISO |
HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBC mRNA] |
CTD |
PMID:30186748 |
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NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
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G |
UBE2C |
ubiquitin conjugating enzyme E2 C |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UBE2C mRNA |
CTD |
PMID:20061341 |
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NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957
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G |
UBE2T |
ubiquitin conjugating enzyme E2 T |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UBE2T mRNA |
CTD |
PMID:20061341 |
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NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984
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G |
UBQLN1 |
ubiquilin 1 |
increases stability |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of UBQLN1 protein mutant form |
CTD |
PMID:24747970 |
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NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958
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G |
UBR1 |
ubiquitin protein ligase E3 component n-recognin 1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBR1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr15:42,942,897...43,106,038
Ensembl chr15:42,942,897...43,106,113
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G |
UBXN1 |
UBX domain protein 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NGLY1 protein binds to UBXN1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] |
CTD |
PMID:15362974 |
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NCBI chr11:62,676,500...62,679,073
Ensembl chr11:62,676,498...62,679,117
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G |
UCHL1 |
ubiquitin C-terminal hydrolase L1 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UCHL1 mRNA |
CTD |
PMID:20061341 |
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NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
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G |
UFD1 |
ubiquitin recognition factor in ER associated degradation 1 |
increases expression multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UFD1 mRNA [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of UFD1 mRNA |
CTD |
PMID:20061341 PMID:25566086 |
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NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202
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G |
UHRF1 |
ubiquitin like with PHD and ring finger domains 1 |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UHRF1 mRNA |
CTD |
PMID:25566086 |
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NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
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G |
ULK1 |
unc-51 like autophagy activating kinase 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein] |
CTD |
PMID:27629431 |
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NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150
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G |
UNC13C |
unc-13 homolog C |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UNC13C mRNA] |
CTD |
PMID:25566086 |
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NCBI chr15:53,837,602...54,633,440
Ensembl chr15:53,978,201...54,628,707
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G |
USP14 |
ubiquitin specific peptidase 14 |
increases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of USP14 mRNA |
CTD |
PMID:20061341 |
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NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629
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G |
USP15 |
ubiquitin specific peptidase 15 |
multiple interactions |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]] |
CTD |
PMID:35478295 |
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NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
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G |
USP28 |
ubiquitin specific peptidase 28 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in decreased expression of USP28 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of USP28 protein] |
CTD |
PMID:20046830 |
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NCBI chr11:113,797,875...113,875,572
Ensembl chr11:113,797,874...113,875,572
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G |
USP7 |
ubiquitin specific peptidase 7 |
multiple interactions |
EXP |
[USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; [USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; Arsenic inhibits the reaction [[USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [[USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [USP7 protein affects the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]; USP7 protein affects the reaction [Arsenic inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]]; USP7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein] |
CTD |
PMID:32802178 PMID:35821281 |
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NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328
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G |
VCAM1 |
vascular cell adhesion molecule 1 |
multiple interactions increases expression |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VCAM1 mRNA |
CTD |
PMID:11698246 PMID:18457675 |
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NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
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G |
VCP |
valosin containing protein |
increases expression multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VCP protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] |
CTD |
PMID:15362974 |
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NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668
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G |
VEGFA |
vascular endothelial growth factor A |
multiple interactions increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VEGFA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of VEGFA protein] |
CTD |
PMID:12590138 PMID:24613819 PMID:28651835 PMID:31850806 PMID:32461003 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
VHL |
von Hippel-Lindau tumor suppressor |
multiple interactions |
EXP |
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]] |
CTD |
PMID:17973296 PMID:19263519 |
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NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,667
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G |
VIM |
vimentin |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AHR protein results in decreased expression of VIM protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [AHR protein binds to VIM protein] |
CTD |
PMID:27752740 |
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NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
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G |
VWF |
von Willebrand factor |
decreases expression |
ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of VWF mRNA |
CTD |
PMID:25566086 |
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NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
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G |
WWTR1 |
WW domain containing transcription regulator 1 |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of WWTR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tcdA protein, Clostridium difficile results in decreased expression of WWTR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [toxB protein, Clostridium difficile results in decreased expression of WWTR1 protein] |
CTD |
PMID:33251692 PMID:33539684 |
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NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714
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G |
XBP1 |
X-box binding protein 1 |
decreases response to substance increases expression multiple interactions |
EXP |
XBP1 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of XBP1 protein alternative form 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of XBP1 protein alternative form]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein] |
CTD |
PMID:19135031 PMID:25568320 PMID:27638906 |
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NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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G |
XIAP |
X-linked inhibitor of apoptosis |
multiple interactions increases ubiquitination increases cleavage |
EXP ISO |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cannabidiol promotes the reaction [DIABLO protein binds to XIAP protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cannabidiol results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cannabidiol results in increased ubiquitination of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [trimethyltin chloride results in decreased expression of XIAP protein]; Cannabidiol promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of XIAP protein] benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of XIAP protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of XIAP protein] |
CTD |
PMID:16287099 PMID:19812371 PMID:21411500 PMID:22627131 PMID:23423712 PMID:31699976 More...
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NCBI chr X:123,859,708...123,913,972
Ensembl chr X:123,859,712...123,913,972
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G |
XPC |
XPC complex subunit, DNA damage recognition and repair factor |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of XPC protein] |
CTD |
PMID:28237621 |
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NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,147...14,178,621
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G |
YAP1 |
Yes1 associated transcriptional regulator |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tcdA protein, Clostridium difficile results in decreased expression of YAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [toxB protein, Clostridium difficile results in decreased expression of YAP1 protein] |
CTD |
PMID:33251692 |
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NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424
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G |
ZBTB8B |
zinc finger and BTB domain containing 8B |
multiple interactions decreases expression |
ISO |
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ZBTB8B mRNA] |
CTD |
PMID:25566086 |
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NCBI chr 1:32,465,072...32,496,686
Ensembl chr 1:32,465,072...32,496,686
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G |
ZFAND2A |
zinc finger AN1-type containing 2A |
increases expression |
ISO EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ZFAND2A mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ZFAND2A protein |
CTD |
PMID:24619424 PMID:25566086 PMID:31540997 |
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NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,152,071...1,160,759
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G |
ZFP36 |
ZFP36 ring finger protein |
multiple interactions |
EXP |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein] |
CTD |
PMID:23288922 |
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NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407
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G |
ZFYVE21 |
zinc finger FYVE-type containing 21 |
multiple interactions |
ISO |
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ZFYVE21 mRNA |
CTD |
PMID:25566086 |
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NCBI chr14:103,715,810...103,733,664
Ensembl chr14:103,715,730...103,733,668
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