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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal
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Accession:CHEBI:75142 term browser browse the term
Definition:A tripeptide that is L-leucyl-L-leucyl-L-leucine in which the C-terminal carboxy group has been reduced to the corresponding aldehyde and the N-terminal amino group is protected as its benzyloxycarbonyl derivative.
Synonyms:exact_synonym: N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide
 related_synonym: (S)-N-((phenylmethoxy)carbonyl)-L-leucyl-N-(1-formyl-3-methylbutyl)-L-leucinamide;   Cbz-L-Leu-L-Leu-L-Leu-CHO;   Cbz-L-Leu-L-Leu-L-Leu-H;   Cbz-Leu-Leu-Leu-CHO;   Cbz-Leu-Leu-Leu-H;   Cbz-Leu-Leu-Leucinal;   Formula=C26H41N3O5;   InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1;   InChIKey=TZYWCYJVHRLUCT-VABKMULXSA-N;   MG 132;   SMILES=C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)=O)=O)(=O)[H];   Z-LLL-CHO;   Z-LLL-H;   Z-LLLal;   Z-Leu-Leu-Leu-CHO;   Z-Leu-Leu-Leu-H;   Z-Leu-Leu-Leu-al;   Z-Leu-Leu-Leucinal;   ZLLL-CHO;   ZLLLal;   benzyloxycarbonyl-leu-leu-leu-aldehyde;   benzyloxycarbonyl-leucyl-leucyl-leucinal;   benzyloxycarbonylleucyl-leucyl-leucine aldehyde;   carbobenzoxy-Leu-Leu-leucinal;   carbobenzoxy-leucyl-leucyl-leucinal;   carbobenzoxyl-leucinyl-leucinyl-leucinal-H
 alt_id: CHEBI:87077
 xref: CAS:133407-82-6;   LINCS:LSM-1107
 xref_mesh: MESH:C072553
 xref: PMID:19513526;   PMID:20053704;   PMID:20471510;   PMID:21421692;   Reaxys:7668447



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N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isoborneol results in decreased expression of ABCB1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CERS6 protein affects the expression of ABCB1 protein]
CTD PMID:26593909 PMID:34915026 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [indolo(3,2-b)carbazole results in increased expression of ABCG2 mRNA] CTD PMID:17077187 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA]
CTD PMID:25566086 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953
JBrowse link
G ACE angiotensin I converting enzyme multiple interactions EXP [Butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of ACE protein mutant form; [Butyrates co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased activity of ACE protein mutant form CTD PMID:20454656 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G ACE2 angiotensin converting enzyme 2 multiple interactions
decreases expression
EXP ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]; ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein] CTD PMID:27638906 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236
JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in decreased stability of ACHE protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of ACHE protein] CTD PMID:22944069 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ACTA2 actin alpha 2, smooth muscle decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTA2 mRNA CTD PMID:25566086 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339
JBrowse link
G ACTB actin beta decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTB mRNA CTD PMID:15857753 NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
JBrowse link
G ACTC1 actin alpha cardiac muscle 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA]
CTD PMID:25566086 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589
JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 multiple interactions
increases expression
EXP 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ADAM17 protein]; 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ADAM17 protein] CTD PMID:27638906 NCBI chr 2:9,488,486...9,555,830
Ensembl chr 2:9,488,486...9,556,732
JBrowse link
G ADSS1 adenylosuccinate synthase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSS1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSS1 mRNA]
CTD PMID:25566086 NCBI chr14:104,724,229...104,747,325
Ensembl chr14:104,724,174...104,747,325
JBrowse link
G AGRP agouti related neuropeptide increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AGRP mRNA CTD PMID:20061341 NCBI chr16:67,482,571...67,483,547
Ensembl chr16:67,482,571...67,483,547
JBrowse link
G AGT angiotensinogen multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] CTD PMID:18487452 PMID:26612707 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
JBrowse link
G AHR aryl hydrocarbon receptor multiple interactions
increases expression
increases localization
affects localization
decreases expression
EXP
ISO
AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [beta-hexachlorocyclohexane affects the expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-formylindolo(3,2-b)carbazole results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AHR protein results in decreased expression of VIM protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [AHR protein results in increased expression of ESR1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [herbimycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [monorden results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and affects the localization of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and results in decreased expression of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [AHR protein binds to VIM protein]
MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of AHR protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of and affects the localization of AHR protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of AHR protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of AHR protein
CTD
RGD
PMID:10497241 PMID:10722677 PMID:10922479 PMID:12002481 PMID:12237327 More... RGD:401794136 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AKR1B1 aldo-keto reductase family 1 member B increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B1 mRNA CTD PMID:21215737 NCBI chr 7:134,442,350...134,459,239
Ensembl chr 7:134,442,356...134,459,284
JBrowse link
G AKR1B10 aldo-keto reductase family 1 member B10 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1B10 mRNA CTD PMID:21215737 NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
JBrowse link
G AKR1C1 aldo-keto reductase family 1 member C1 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Salicylic Acid inhibits the reaction [AKR1C1 protein results in decreased susceptibility to Cisplatin]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C1 mRNA
CTD PMID:21215737 PMID:23165153 NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C3 mRNA
CTD PMID:21215737 PMID:23165153 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased phosphorylation of AKT1 protein]
AKT1 protein modified form inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with dihydromyricetin] results in increased ubiquitination of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [sodium arsenite affects the expression of AKT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tubocapsenolide A results in increased degradation of AKT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of AKT1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKT1 protein
CTD PMID:18442981 PMID:24085292 PMID:24449419 PMID:24933620 PMID:32061799 More... NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759
JBrowse link
G ANLN anillin, actin binding protein decreases expression ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ANLN mRNA CTD PMID:25566086 PMID:31806706 NCBI chr 7:36,389,862...36,453,791
Ensembl chr 7:36,389,821...36,453,791
JBrowse link
G ANXA2 annexin A2 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ANXA2 mRNA CTD PMID:31806706 NCBI chr15:60,347,151...60,397,986
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G AOC3 amine oxidase copper containing 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of AOC3 mRNA CTD PMID:25566086 NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130
JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA]
CTD PMID:25566086 NCBI chr 1:150,265,404...150,269,016
Ensembl chr 1:150,265,399...150,269,580
JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] CTD PMID:21520056 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Poly I-C results in increased degradation of APPL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resiquimod results in increased degradation of APPL1 protein] CTD PMID:25780039 NCBI chr 3:57,227,729...57,273,471
Ensembl chr 3:57,227,726...57,278,105
JBrowse link
G AQP2 aquaporin 2 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of AQP2 protein CTD PMID:21734099 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
JBrowse link
G AQP3 aquaporin 3 (Gill blood group) multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]] CTD PMID:23545307 NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
JBrowse link
G AQP5 aquaporin 5 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]] CTD PMID:23545307 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682
JBrowse link
G AR androgen receptor multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [decursin results in increased degradation of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [isobavachin results in decreased expression of and results in increased degradation of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulforaphane results in decreased expression of AR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Testosterone results in increased expression of AR mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of AR protein] CTD PMID:12376534 PMID:17723170 PMID:19805354 PMID:24740322 PMID:37019376 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARG1 arginase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA]
CTD PMID:25566086 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARIH1 protein]
CTD PMID:25624349 NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
JBrowse link
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]] CTD PMID:21600884 NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator increases expression
multiple interactions
decreases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARNT mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in increased degradation of ARNT protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARNT protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [SP1 protein binds to ARNT promoter]; bisindolylmaleimide I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ARNT mRNA]
CTD PMID:14529614 PMID:15899923 PMID:16880289 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708
JBrowse link
G ART3 ADP-ribosyltransferase 3 (inactive) decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA]
CTD PMID:25566086 NCBI chr 4:76,011,190...76,112,786
Ensembl chr 4:76,011,184...76,114,048
JBrowse link
G ASB2 ankyrin repeat and SOCS box containing 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ASB2 mRNA CTD PMID:25566086 NCBI chr14:93,934,166...93,976,570
Ensembl chr14:93,934,166...93,976,739
JBrowse link
G ATF3 activating transcription factor 3 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF3 protein]
CTD PMID:23593480 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
JBrowse link
G ATF4 activating transcription factor 4 increases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein
Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF4 protein]
CTD PMID:14604972 PMID:17912641 PMID:23593480 PMID:31806706 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G ATF6 activating transcription factor 6 multiple interactions
increases expression
EXP 4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ATF6 protein]; ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]; ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein] CTD PMID:27638906 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
G ATG12 autophagy related 12 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA CTD PMID:25566086 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
JBrowse link
G ATG13 autophagy related 13 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818
JBrowse link
G ATG7 autophagy related 7 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein] CTD PMID:27629431 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G ATP13A2 ATPase cation transporting 13A2 decreases response to substance EXP ATP13A2 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde analog CTD PMID:22847264 NCBI chr 1:16,985,958...17,011,928
Ensembl chr 1:16,985,958...17,011,928
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein] CTD PMID:10506578 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP5F1B ATP synthase F1 subunit beta multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of ATP5F1B mRNA] CTD PMID:20860658 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G ATP7B ATPase copper transporting beta decreases degradation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of ATP7B protein CTD PMID:21189263 NCBI chr13:51,932,669...52,012,132
Ensembl chr13:51,930,436...52,012,125
JBrowse link
G AURKA aurora kinase A multiple interactions EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased expression of and results in increased phosphorylation of AURKA protein; MLN8054 inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKA protein] CTD PMID:24976383 NCBI chr20:56,369,390...56,392,215
Ensembl chr20:56,369,389...56,392,337
JBrowse link
G AURKB aurora kinase B multiple interactions EXP 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKB protein CTD PMID:24976383 NCBI chr17:8,204,731...8,210,575
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G BACH1 BTB domain and CNC homolog 1 multiple interactions
increases expression
increases ubiquitination
EXP 2-tert-butylhydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] affects the localization of BACH1 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of BACH1 protein; [Hemin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of BACH1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tetrachlorobenzoquinone results in increased degradation of BACH1 protein]; hydroquinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]; quinone promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BACH1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BACH1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BACH1 protein
CTD PMID:27393035 PMID:28645578 PMID:33434570 NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751
JBrowse link
G BAG3 BAG cochaperone 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Staurosporine results in increased degradation of BAG3 protein] CTD PMID:19352495 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases ubiquitination EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of BAK1 protein CTD PMID:36346691 NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of BAX protein
MitoTEMPO inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BAX protein]
CTD PMID:15782132 PMID:19540902 PMID:34418242 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BBC3 BCL2 binding component 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
JBrowse link
G BCAS2 BCAS2 pre-mRNA processing factor decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCAS2 mRNA CTD PMID:31806706 NCBI chr 1:114,567,557...114,581,615
Ensembl chr 1:114,567,557...114,581,629
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [evodiamine results in increased cleavage of BCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [trimethyltin chloride results in decreased expression of BCL2 protein]
benzyloxycarbonyl-valyl-alanyl-aspartic acid promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein]; MitoTEMPO inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2 protein
CTD PMID:19540902 PMID:20005289 PMID:20100472 PMID:20449726 PMID:23423712 More... NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BCL2L1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BCL2L1 protein]
CTD PMID:16960866 PMID:19540902 PMID:19812371 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCL2L11 BCL2 like 11 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased degradation of BCL2L11 protein] CTD PMID:36509116 NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
JBrowse link
G BIRC2 baculoviral IAP repeat containing 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC2 protein results in increased degradation of SOD1 protein mutant form] CTD PMID:27773815 NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670
JBrowse link
G BIRC3 baculoviral IAP repeat containing 3 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC3 protein results in increased degradation of SOD1 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC3 protein
CTD PMID:14527959 PMID:24085292 PMID:27773815 NCBI chr11:102,317,484...102,339,403
Ensembl chr11:102,317,484...102,339,403
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 increases expression
multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BIRC5 protein
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with dihydromyricetin] results in increased ubiquitination of BIRC5 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with MK 2206] results in increased ubiquitination of BIRC5 protein; AKT1 protein modified form inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with dihydromyricetin] results in increased ubiquitination of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [dihydromyricetin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of BIRC5 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to [Oxaliplatin results in decreased expression of BIRC5 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of BIRC5 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of BIRC5 protein]
CTD PMID:16328441 PMID:17510429 PMID:17548900 PMID:19812371 PMID:19939880 More... NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G BLVRB biliverdin reductase B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BLVRB mRNA CTD PMID:25566086 NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764
JBrowse link
G BMI1 BMI1 proto-oncogene, polycomb ring finger increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BMI1 protein CTD PMID:33157086 NCBI chr10:22,321,099...22,331,484
Ensembl chr10:22,321,099...22,331,484
JBrowse link
G BNIP3 BCL2 interacting protein 3 multiple interactions
increases expression
EXP [arsenic trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of BNIP3 mRNA; arsenic trioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of BNIP3 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Valproic Acid results in increased expression of BNIP3 mRNA] CTD PMID:25446377 NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
JBrowse link
G BOK BCL2 family apoptosis regulator BOK multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of BOK mRNA CTD PMID:25566086 NCBI chr 2:241,551,393...241,574,131
Ensembl chr 2:241,551,424...241,574,131
JBrowse link
G BRD4 bromodomain containing 4 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]]
CTD PMID:23686307 PMID:25877301 PMID:26051217 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545
JBrowse link
G C1QB complement C1q B chain multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of C1QB mRNA] CTD PMID:25566086 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637
JBrowse link
G CA14 carbonic anhydrase 14 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA]
CTD PMID:25566086 NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078
JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H decreases expression
decreases degradation
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CACNA1H mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CACNA1H protein
CTD PMID:25566086 PMID:30552955 NCBI chr16:1,153,106...1,221,768
Ensembl chr16:1,153,103...1,224,169
JBrowse link
G CANX calnexin affects localization EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of CANX protein CTD PMID:17912641 NCBI chr 5:179,678,656...179,731,641
Ensembl chr 5:179,678,628...179,731,641
JBrowse link
G CAPN1 calpain 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in increased expression of CAPN1 protein] CTD PMID:37353096 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006
JBrowse link
G CASP1 caspase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]] CTD PMID:15914627 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
JBrowse link
G CASP3 caspase 3 multiple interactions
increases cleavage
increases expression
increases activity
EXP
ISO
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CASP3 protein]; [Arsenic Trioxide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased cleavage of CASP3 protein; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [evodiamine results in increased activity of and results in increased cleavage of CASP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CASP3 protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein
Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein]
CTD PMID:15498850 PMID:15725397 PMID:16880202 PMID:18463101 PMID:18790767 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP6 caspase 6 multiple interactions
decreases activity
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of CASP6 protein
CTD PMID:15914627 NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
JBrowse link
G CASP7 caspase 7 increases activity EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP7 protein CTD PMID:19139269 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASP8 caspase 8 multiple interactions
increases activity
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP8 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP8 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]]
CTD PMID:15498850 PMID:15914627 PMID:20100472 PMID:20449726 PMID:20671745 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of and results in increased activity of CASP9 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP9 protein
CTD PMID:15498850 PMID:16880202 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAST calpastatin multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in increased cleavage of CAST protein] CTD PMID:37353096 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,525,267...96,779,595
Ensembl chr 5:96,525,267...96,779,595
JBrowse link
G CAT catalase increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CAT mRNA
CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein]
CTD PMID:20061341 PMID:24973648 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 decreases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAV1 protein
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CAV1 mRNA
CTD PMID:19706615 PMID:25566086 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CAVIN1 caveolae associated protein 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN1 mRNA] CTD PMID:25566086 NCBI chr17:42,402,449...42,423,256
Ensembl chr17:42,402,449...42,423,256
JBrowse link
G CAVIN2 caveolae associated protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN2 mRNA CTD PMID:25566086 NCBI chr 2:191,834,310...191,847,088
Ensembl chr 2:191,834,310...191,847,088
JBrowse link
G CBR3 carbonyl reductase 3 increases expression EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein] which results in increased expression of CBR3 mRNA CTD PMID:20806931 NCBI chr21:36,135,079...36,146,562
Ensembl chr21:36,135,079...36,146,562
JBrowse link
G CCL2 C-C motif chemokine ligand 2 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]
CTD PMID:10541287 PMID:11230753 PMID:11698246 PMID:15139008 PMID:19945525 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
JBrowse link
G CCL23 C-C motif chemokine ligand 23 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCL9 mRNA CTD PMID:25566086 NCBI chr17:36,013,058...36,017,972
Ensembl chr17:36,013,056...36,017,972
JBrowse link
G CCNA2 cyclin A2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNA2 mRNA CTD PMID:20061341 NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
JBrowse link
G CCNB1 cyclin B1 multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [arsenite results in increased ubiquitination of CCNB1 protein]
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB1 mRNA
CTD PMID:17373649 PMID:20061341 PMID:25566086 NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
JBrowse link
G CCNB2 cyclin B2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCNB2 mRNA CTD PMID:20061341 NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
JBrowse link
G CCND1 cyclin D1 multiple interactions
increases expression
increases phosphorylation
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3,3'-diindolylmethane analog results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alopestatin metabolite results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of CCND1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [kahweol results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lysocellin results in decreased expression of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased phosphorylation of CCND1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased degradation of CCND1 protein]; Tetrachlorodibenzodioxin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of CCND1 protein]
CTD PMID:15247282 PMID:16051428 PMID:16525630 PMID:16707792 PMID:16965676 More... NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCND3 cyclin D3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CCND3 mRNA CTD PMID:20061341 NCBI chr 6:41,934,933...42,050,035
Ensembl chr 6:41,934,934...42,050,357
JBrowse link
G CCS copper chaperone for superoxide dismutase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Copper Sulfate co-treated with 2,3,2-tetramine] results in increased degradation of CCS protein] CTD PMID:12832419 NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G CD14 CD14 molecule increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA]
CTD PMID:25566086 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700
JBrowse link
G CD1D CD1d molecule increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD1D1 mRNA CTD PMID:25566086 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427
JBrowse link
G CD248 CD248 molecule decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CD248 mRNA CTD PMID:25566086 NCBI chr11:66,314,494...66,317,044
Ensembl chr11:66,314,494...66,317,044
JBrowse link
G CD36 CD36 molecule (CD36 blood group) multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD36 protein] CTD PMID:36534932 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
JBrowse link
G CDC20 cell division cycle 20 multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of CDC20 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC20 mRNA
CTD PMID:20054826 PMID:20061341 PMID:25566086 NCBI chr 1:43,358,981...43,363,203
Ensembl chr 1:43,358,981...43,363,203
JBrowse link
G CDC25B cell division cycle 25B decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC25B mRNA CTD PMID:20061341 NCBI chr20:3,786,951...3,806,115
Ensembl chr20:3,786,772...3,806,121
JBrowse link
G CDC25C cell division cycle 25C decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDC25C mRNA CTD PMID:20061341 NCBI chr 5:138,285,265...138,338,355
Ensembl chr 5:138,285,269...138,338,355
JBrowse link
G CDCA3 cell division cycle associated 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDCA3 mRNA CTD PMID:20061341 NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
JBrowse link
G CDH3 cadherin 3 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDH3 mRNA CTD PMID:25566086 NCBI chr16:68,645,310...68,733,771
Ensembl chr16:68,636,189...68,727,468
JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDK1 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDK1 mRNA
CTD PMID:20061341 PMID:25566086 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDK2 cyclin dependent kinase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of CDK2 protein] CTD PMID:15610522 NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789
JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B decreases degradation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CDKN1B protein CTD PMID:17283133 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2A mRNA CTD PMID:20061341 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
JBrowse link
G CDKN2C cyclin dependent kinase inhibitor 2C decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN2C mRNA CTD PMID:20061341 NCBI chr 1:50,968,706...50,974,634
Ensembl chr 1:50,960,745...50,974,634
JBrowse link
G CDKN3 cyclin dependent kinase inhibitor 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CDKN3 mRNA CTD PMID:20061341 NCBI chr14:54,397,007...54,420,218
Ensembl chr14:54,396,849...54,420,218
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha increases ubiquitination
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of CEBPA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of CEBPA protein]
CTD PMID:19662097 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CEBPB CCAAT enhancer binding protein beta multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPB protein; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPB protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [N-acetylsphingosine results in decreased localization of CEBPB protein]
CTD PMID:11779194 PMID:15319326 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
JBrowse link
G CEBPD CCAAT enhancer binding protein delta multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPD protein; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased localization of CEBPD protein] CTD PMID:11779194 NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164
JBrowse link
G CEBPE CCAAT enhancer binding protein epsilon multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of CEBPE protein] CTD PMID:20945414 NCBI chr14:23,117,306...23,119,255
Ensembl chr14:23,117,036...23,120,256
JBrowse link
G CENPA centromere protein A decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA]
CTD PMID:25566086 NCBI chr 2:26,786,056...26,794,589
Ensembl chr 2:26,764,289...26,801,067
JBrowse link
G CERS6 ceramide synthase 6 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CERS6 protein affects the expression of ABCB1 protein] CTD PMID:34915026 NCBI chr 2:168,456,272...168,775,134
Ensembl chr 2:168,456,249...168,775,134
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator affects expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of CFLAR protein alternative form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound results in decreased expression of CFLAR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [alvocidib results in decreased expression of CFLAR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of CFLAR protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [shogaol results in decreased expression of CFLAR protein modified form]
CTD PMID:16951203 PMID:17510429 PMID:18980244 PMID:25619640 PMID:26415225 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CFTR CF transmembrane conductance regulator multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat results in increased activity of CFTR protein mutant form] CTD PMID:18230692 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G CHEK1 checkpoint kinase 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHEK1 mRNA CTD PMID:20061341 NCBI chr11:125,625,136...125,681,124
Ensembl chr11:125,625,163...125,676,255
JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHRM2 mRNA] CTD PMID:25566086 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255
JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex increases activity EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CHUK protein CTD PMID:24085292 NCBI chr10:100,186,319...100,229,596
Ensembl chr10:100,188,300...100,229,596
JBrowse link
G CIDEA cell death inducing DFFA like effector a decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CIDEA mRNA CTD PMID:25566086 NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
JBrowse link
G CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CITED4 mRNA CTD PMID:25566086 NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363
JBrowse link
G CKB creatine kinase B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CKB mRNA CTD PMID:25566086 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CKMT2 creatine kinase, mitochondrial 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA]
CTD PMID:25566086 NCBI chr 5:81,233,322...81,266,398
Ensembl chr 5:81,233,320...81,266,398
JBrowse link
G CLDN4 claudin 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA]
CTD PMID:25566086 NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690
JBrowse link
G CLDN5 claudin 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein] CTD PMID:34391839 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
JBrowse link
G CLIP4 CAP-Gly domain containing linker protein family member 4 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CLIP4 mRNA] CTD PMID:25566086 NCBI chr 2:29,097,726...29,183,808
Ensembl chr 2:29,097,705...29,199,777
JBrowse link
G CMYA5 cardiomyopathy associated 5 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CMYA5 mRNA] CTD PMID:25566086 NCBI chr 5:79,689,836...79,800,222
Ensembl chr 5:79,689,836...79,800,240
JBrowse link
G CNR1 cannabinoid receptor 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
JBrowse link
G CNR2 cannabinoid receptor 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362
JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA] CTD PMID:11306436 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COMMD1 copper metabolism domain containing 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of COMMD1 protein CTD PMID:23401744 NCBI chr 2:61,888,391...62,136,058
Ensembl chr 2:61,888,724...62,147,247
JBrowse link
G CORIN corin, serine peptidase decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA]
CTD PMID:25566086 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106
JBrowse link
G COX4I2 cytochrome c oxidase subunit 4I2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of COX4I2 mRNA CTD PMID:25566086 NCBI chr20:31,637,912...31,645,006
Ensembl chr20:31,637,912...31,645,006
JBrowse link
G CPXM1 carboxypeptidase X, M14 family member 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CPXM1 mRNA CTD PMID:20061341 PMID:25566086 NCBI chr20:2,794,074...2,800,627
Ensembl chr20:2,794,074...2,800,627
JBrowse link
G CRCT1 cysteine rich C-terminal 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CRCT1 mRNA CTD PMID:25566086 NCBI chr 1:152,514,482...152,516,008
Ensembl chr 1:152,514,482...152,516,008
JBrowse link
G CREBBP CREB binding protein multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Valproic Acid results in decreased expression of CREBBP protein] CTD PMID:27381264 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713
JBrowse link
G CRIP2 cysteine rich protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRIP2 mRNA CTD PMID:25566086 NCBI chr14:105,472,945...105,480,170
Ensembl chr14:105,472,962...105,480,162
JBrowse link
G CRYAA crystallin alpha A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRYAA mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CRYAA protein CTD PMID:15914627 NCBI chr21:43,169,008...43,172,810
Ensembl chr21:43,169,008...43,172,805
JBrowse link
G CRYAB crystallin alpha B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CRYAB mRNA CTD PMID:15914627 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
JBrowse link
G CSNK2B casein kinase 2 beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in increased degradation of CSNK2B protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNFAIP1 protein results in increased degradation of CSNK2B protein] CTD PMID:37302538 NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343
JBrowse link
G CST5 cystatin D decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CST5 mRNA CTD PMID:31806706 NCBI chr20:23,875,934...23,879,748
Ensembl chr20:23,875,934...23,879,748
JBrowse link
G CTNNB1 catenin beta 1 multiple interactions
decreases degradation
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [bruceine D affects the reaction [Oxygen deficiency affects the expression of CTNNB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arctigenin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Aspirin results in increased ubiquitination of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RASSF5 protein results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vitamin A results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Nitroglycerin results in increased degradation of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of CTNNB1 protein; thymoquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of CTNNB1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the phosphorylation of and affects the localization of CTNNB1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of CTNNB1 protein; Phenobarbital inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CTNNB1 protein]
CTD PMID:14555707 PMID:16878161 PMID:17030184 PMID:17219422 PMID:20510325 More... NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G CTSD cathepsin D increases cleavage
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]; ATF6 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]; ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]
CTD PMID:27638906 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CUL2 cullin 2 multiple interactions EXP CUL2 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MAF1 protein] CTD PMID:31645432 NCBI chr10:35,008,551...35,127,006
Ensembl chr10:35,008,504...35,127,006
JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CX3CL1 mRNA] CTD PMID:11698246 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
JBrowse link
G CXCL1 C-X-C motif chemokine ligand 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein] CTD PMID:11698246 NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CXCL12 mRNA CTD PMID:25566086 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions
increases expression
increases secretion
EXP Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Antimycin A inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chloroquine results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Titanium results in increased secretion of CXCL8 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; diphenyleneiodonium inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Glutathione inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]; Rotenone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CXCL8 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased secretion of CXCL8 protein
CTD PMID:11698246 PMID:12208513 PMID:15139008 PMID:16392133 PMID:18457675 More... NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TPD7 compound results in decreased expression of CXCR4 protein] CTD PMID:25753200 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G CYCS cytochrome c, somatic affects localization ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of CYCS protein CTD PMID:15725397 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression
increases activity
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with Harmaline] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cycloheximide co-treated with harmalol] results in decreased expression of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Harmine results in decreased stability of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [harmol results in decreased stability of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CYP1A1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CYP1A1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CYP1A1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Lead results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:10722677 PMID:10777561 PMID:16093525 PMID:16891617 PMID:17606337 More... NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression ISO MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats RGD PMID:22079846 RGD:401794136 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 increases stability EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of CYP1B1 protein CTD PMID:15486049 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902
JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CYP26A1 mRNA CTD PMID:31806706 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital results in increased expression of CYP2B6 mRNA] CTD PMID:24224465 NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital results in increased expression of CYP3A4 mRNA] CTD PMID:24224465 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G DDC dopa decarboxylase decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of DDC mRNA CTD PMID:25566086 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405
JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions
increases expression
increases activity
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of DDIT3 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of DDIT3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DDIT3 protein
CTD PMID:17912641 PMID:19135031 PMID:19139269 PMID:22959925 PMID:23684743 More... NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
JBrowse link
G DFFA DNA fragmentation factor subunit alpha multiple interactions ISO DFFA protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DFFB protein] CTD PMID:18178165 NCBI chr 1:10,456,522...10,472,529
Ensembl chr 1:10,456,522...10,472,529
JBrowse link
G DFFB DNA fragmentation factor subunit beta multiple interactions
decreases degradation
increases ubiquitination
ISO DFFA protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DFFB protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of DFFB protein
CTD PMID:18178165 NCBI chr 1:3,857,476...3,885,429
Ensembl chr 1:3,857,267...3,885,429
JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cannabidiol promotes the reaction [DIABLO protein binds to XIAP protein]] CTD PMID:31699976 NCBI chr12:122,207,662...122,227,456
Ensembl chr12:122,207,668...122,226,062
JBrowse link
G DIO2 iodothyronine deiodinase 2 multiple interactions
increases expression
increases activity
EXP
ISO
[Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [2,2',4,4',5-brominated diphenyl ether metabolite results in decreased activity of DIO2 protein]; [Cycloheximide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased activity of DIO2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [decabromobiphenyl ether results in increased degradation of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Thyroxine results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased activity of DIO2 protein; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2,2',4,4',5-brominated diphenyl ether results in decreased activity of DIO2 protein]]; Cycloheximide promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Triiodothyronine, Reverse results in decreased activity of DIO2 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DIO2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of DIO2 protein
CTD PMID:11425850 PMID:17615150 PMID:26004626 PMID:37330034 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJB1 protein CTD PMID:15525353 PMID:25566086 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391
JBrowse link
G DNAJC2 DnaJ heat shock protein family (Hsp40) member C2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNAJC2 mRNA CTD PMID:25566086 NCBI chr 7:103,312,289...103,344,767
Ensembl chr 7:103,312,289...103,344,830
JBrowse link
G DNAJC7 DnaJ heat shock protein family (Hsp40) member C7 multiple interactions
increases ubiquitination
ISO 1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [DNAJC7 protein results in increased expression of NR1I3 protein]; NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]] CTD PMID:24789201 NCBI chr17:41,976,435...42,017,439
Ensembl chr17:41,976,421...42,021,376
JBrowse link
G DNMT1 DNA methyltransferase 1 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of DNMT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [quinoline analog results in increased degradation of DNMT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT1 protein]
CTD PMID:19417133 PMID:21150308 PMID:23395981 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3A protein] CTD PMID:23395981 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNMT3B DNA methyltransferase 3 beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3B protein] CTD PMID:23395981 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,359
JBrowse link
G DNMT3L DNA methyltransferase 3 like multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNMT3L mRNA] CTD PMID:25566086 NCBI chr21:44,246,339...44,261,897
Ensembl chr21:44,246,339...44,262,216
JBrowse link
G DPP7 dipeptidyl peptidase 7 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[DPP7 protein results in increased cleavage of Dipeptides] which results in increased abundance of 4-nitroaniline] CTD PMID:16725115 NCBI chr 9:137,110,546...137,118,306
Ensembl chr 9:137,110,542...137,118,309
JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SKP2 protein results in decreased expression of DUSP1 protein] CTD PMID:34697729 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
JBrowse link
G DYNC1H1 dynein cytoplasmic 1 heavy chain 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA]
CTD PMID:25566086 NCBI chr14:101,964,573...102,056,443
Ensembl chr14:101,964,573...102,056,443
JBrowse link
G DYNC1I1 dynein cytoplasmic 1 intermediate chain 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1I1 mRNA CTD PMID:20061341 NCBI chr 7:95,772,554...96,110,322
Ensembl chr 7:95,772,506...96,110,322
JBrowse link
G E2F1 E2F transcription factor 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dronabinol results in decreased expression of E2F1 protein] CTD PMID:17934890 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G E2F2 E2F transcription factor 2 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of E2F2 mRNA CTD PMID:31806706 NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233
JBrowse link
G EDN1 endothelin 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EDN1 mRNA CTD PMID:18457675 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EGF epidermal growth factor multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EGF mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]]
CTD PMID:22689575 PMID:22766066 PMID:31806706 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFL7 EGF like domain multiple 7 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of EGFL7 mRNA CTD PMID:25566086 NCBI chr 9:136,658,856...136,672,678
Ensembl chr 9:136,658,856...136,672,678
JBrowse link
G EGFR epidermal growth factor receptor multiple interactions
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MUC1 affects the expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGFR protein
CTD PMID:17146438 PMID:20332299 PMID:22457794 PMID:28711525 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN1 mRNA] CTD PMID:25566086 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287
JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA]
CTD PMID:25566086 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of EIF2AK2 mRNA CTD PMID:25566086 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1,2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2AK3 protein
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2AK3 protein]
CTD PMID:22959925 PMID:27638906 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EIF2S1 protein modified form
CTD PMID:21090173 PMID:22321511 PMID:23684743 PMID:25568320 PMID:27638906 More... NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
JBrowse link
G EIF4E eukaryotic translation initiation factor 4E multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in decreased expression of EIF4E protein] CTD PMID:15878868 NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133
JBrowse link
G ELAVL1 ELAV like RNA binding protein 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ELAVL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ELAVL1 protein CTD PMID:23922739 NCBI chr19:7,958,573...8,005,641
Ensembl chr19:7,958,573...8,005,659
JBrowse link
G EMCN endomucin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EMCN mRNA CTD PMID:25566086 NCBI chr 4:100,395,341...100,518,022
Ensembl chr 4:100,395,341...100,880,126
JBrowse link
G ENO3 enolase 3 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA]
CTD PMID:25566086 NCBI chr17:4,948,710...4,957,129
Ensembl chr17:4,948,092...4,957,131
JBrowse link
G EP300 E1A binding protein p300 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of EP300 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased degradation of EP300 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SIRT6 protein results in decreased expression of EP300 protein]
CTD PMID:15767673 PMID:17927689 PMID:27094368 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077
JBrowse link
G EPAS1 endothelial PAS domain protein 1 multiple interactions
increases ubiquitination
increases expression
increases hydroxylation
increases stability
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPAS1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein
[Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; [Formaldehyde co-treated with VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; [VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein; arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [MALAT1 mRNA promotes the reaction [sodium arsenite results in increased expression of EPAS1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of EPAS1 protein]; MALAT1 mRNA promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]; MALAT1 mRNA promotes the reaction [sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]]; sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of EPAS1 protein
CTD PMID:22447124 PMID:23545307 PMID:26735578 PMID:35504338 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
JBrowse link
G EPHB4 EPH receptor B4 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Homoharringtonine results in decreased expression of EPHB4 protein] CTD PMID:31726078 NCBI chr 7:100,802,565...100,827,523
Ensembl chr 7:100,802,565...100,827,523
JBrowse link
G EPHX1 epoxide hydrolase 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX1 mRNA CTD PMID:20061341 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
JBrowse link
G EPHX2 epoxide hydrolase 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX2 mRNA CTD PMID:20061341 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564
JBrowse link
G EPO erythropoietin multiple interactions
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of EPO protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of EPO protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPO protein
CTD PMID:31850806 PMID:32461003 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700
JBrowse link
G EPPK1 epiplakin 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EPPK1 mRNA CTD PMID:25566086 NCBI chr 8:143,857,324...143,879,194
Ensembl chr 8:143,857,324...143,878,467
JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 decreases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Berberine results in decreased expression of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [demethoxycurcumin results in increased degradation of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of ERBB2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB2 protein]
CTD PMID:18655187 PMID:20332299 PMID:31806706 PMID:33325633 PMID:34291863 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426
JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 multiple interactions
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of ERBB3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of ERBB3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ERBB3 protein
CTD PMID:20332299 NCBI chr12:56,080,108...56,103,505
Ensembl chr12:56,076,799...56,103,505
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein] CTD PMID:25440059 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538
JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions
increases phosphorylation
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ERN1 protein
ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACE2 protein]; ERN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of CTSD protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of ERN1 protein
CTD PMID:19139269 PMID:27638906 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions
increases ubiquitination
decreases expression
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-prenylnaringenin results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [8-prenylnaringenin results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [baohuoside I results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Butyrophenones results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Carbamazepine results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate inhibits the reaction [AHR protein results in increased expression of ESR1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fulvestrant results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Okadaic Acid results in increased degradation of ESR1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Plant Extracts results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [xanthohumol results in decreased expression of ESR1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of ESR1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ESR1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in increased degradation of ESR1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [PTK2B protein affects the ubiquitination of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol results in decreased expression of ESR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Gonadotropin-Releasing Hormone results in decreased expression of ESR1 protein]
CTD PMID:12612060 PMID:14702340 PMID:14750165 PMID:15965230 PMID:16055746 More... NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Estradiol results in increased expression of ESR2 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESR2 protein
CTD PMID:14702340 PMID:15207704 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G ESRRA estrogen related receptor alpha increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ESRRA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HDAC6 protein results in increased expression of ESRRA protein]
CTD PMID:34524571 NCBI chr11:64,305,524...64,316,743
Ensembl chr11:64,305,497...64,316,743
JBrowse link
G FAHD1 fumarylacetoacetate hydrolase domain containing 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of FAHD1 mRNA CTD PMID:25566086 NCBI chr16:1,827,206...1,840,207
Ensembl chr16:1,826,967...1,840,207
JBrowse link
G FAM13B family with sequence similarity 13 member B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of FAM13B mRNA CTD PMID:25566086 NCBI chr 5:137,937,960...138,052,178
Ensembl chr 5:137,937,960...138,051,961
JBrowse link
G FAM78A family with sequence similarity 78 member A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FAM78A mRNA CTD PMID:25566086 NCBI chr 9:131,258,078...131,281,045
Ensembl chr 9:131,258,076...131,277,365
JBrowse link
G FASLG Fas ligand multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased expression of FASLG protein] CTD PMID:20005289 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G FBXL12 F-box and leucine rich repeat protein 12 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXL12 mRNA CTD PMID:20061341 NCBI chr19:9,810,270...9,819,079
Ensembl chr19:9,810,267...9,827,816
JBrowse link
G FBXO10 F-box protein 10 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXO10 mRNA] CTD PMID:25566086 NCBI chr 9:37,510,892...37,576,380
Ensembl chr 9:37,510,892...37,576,380
JBrowse link
G FBXO2 F-box protein 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FBXO2 mRNA CTD PMID:25566086 NCBI chr 1:11,648,387...11,654,429
Ensembl chr 1:11,637,018...11,655,785
JBrowse link
G FBXO32 F-box protein 32 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [FBXO32 protein results in decreased expression of KCNN2 protein] CTD PMID:30635400 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
JBrowse link
G FBXO6 F-box protein 6 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FBXO6 mRNA CTD PMID:20061341 NCBI chr 1:11,664,200...11,674,354
Ensembl chr 1:11,664,200...11,674,354
JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 multiple interactions ISO FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]] CTD PMID:24457827 NCBI chr 4:152,320,544...152,536,092
Ensembl chr 4:152,320,544...152,536,092
JBrowse link
G FHL2 four and a half LIM domains 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FHL2 mRNA CTD PMID:25566086 NCBI chr 2:105,357,712...105,438,529
Ensembl chr 2:105,357,712...105,438,513
JBrowse link
G FIS1 fission, mitochondrial 1 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[ponasterone A results in increased expression of PINK1 protein] which results in decreased expression of FIS1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FIS1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[PARK protein co-treated with UBB protein] results in decreased expression of FIS1 protein]
CTD PMID:20164189 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316
JBrowse link
G FLNC filamin C increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FLNC mRNA CTD PMID:25566086 NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274
JBrowse link
G FN1 fibronectin 1 decreases secretion EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased secretion of FN1 protein CTD PMID:11594554 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hydrogen Peroxide results in increased expression of FOS protein]
[Arachidonic Acid co-treated with Quercetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of FOS protein
CTD PMID:15136564 PMID:20551291 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]] CTD PMID:17148446 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
JBrowse link
G FOXM1 forkhead box M1 multiple interactions
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [palbociclib results in decreased expression of FOXM1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FOXM1 mRNA
CTD PMID:22094256 PMID:31806706 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174
JBrowse link
G FOXO1 forkhead box O1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [dorsomorphin results in decreased expression of FOXO1 protein] CTD PMID:25065674 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641
JBrowse link
G FOXO3 forkhead box O3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in increased expression of FOXO3 protein] CTD PMID:31421153 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G FSD2 fibronectin type III and SPRY domain containing 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FSD2 mRNA CTD PMID:25566086 NCBI chr15:82,755,362...82,806,069
Ensembl chr15:82,755,362...82,806,070
JBrowse link
G FTH1 ferritin heavy chain 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein] CTD PMID:16707465 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634
JBrowse link
G FTL ferritin light chain multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein] CTD PMID:16707465 NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879
JBrowse link
G FUNDC1 FUN14 domain containing 1 multiple interactions
increases expression
EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Rotenone] results in increased expression of FUNDC1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Rotenone results in decreased expression of FUNDC1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of FUNDC1 protein
CTD PMID:32001317 PMID:37156403 NCBI chr  X:44,523,639...44,542,859
Ensembl chr  X:44,523,639...44,542,859
JBrowse link
G G0S2 G0/G1 switch 2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of G0S2 mRNA CTD PMID:25566086 NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390
JBrowse link
G GABARAPL1 GABA type A receptor associated protein like 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GABARAPL1 mRNA CTD PMID:31806706 NCBI chr12:10,212,877...10,223,128
Ensembl chr12:10,212,458...10,223,128
JBrowse link
G GABBR2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction and affects the localization of [PSMC5 protein binds to GABBR2 protein] CTD PMID:24482233 NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935
JBrowse link
G GAD1 glutamate decarboxylase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD1 protein] CTD PMID:29107683 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151
JBrowse link
G GAD2 glutamate decarboxylase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of GAD2 protein] CTD PMID:29107683 NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558
JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GADD45A mRNA CTD PMID:20061341 PMID:25566086 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334
JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of GADD45G mRNA CTD PMID:25566086 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit multiple interactions
increases expression
EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLC mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC protein
CTD PMID:25263748 PMID:30186748 PMID:33434570 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GCLM protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLM protein
CTD PMID:20061341 PMID:33434570 NCBI chr 1:93,885,199...93,909,430
Ensembl chr 1:93,885,199...93,909,456
JBrowse link
G GDF15 growth differentiation factor 15 multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA] CTD PMID:25566086 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [antofine results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ioxynil analog results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ioxynil results in decreased expression of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [fulvestrant results in decreased expression of GJA1 protein]
CTD PMID:15685554 PMID:20510257 PMID:23403203 PMID:29180066 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA5 gap junction protein alpha 5 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GJA5 mRNA CTD PMID:25566086 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G GLS glutaminase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diphenylarsinic acid results in increased degradation of GLS protein alternative form] CTD PMID:22493432 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
JBrowse link
G GPR146 G protein-coupled receptor 146 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of GPR146 mRNA CTD PMID:25566086 NCBI chr 7:1,044,546...1,059,261
Ensembl chr 7:1,044,546...1,059,261
JBrowse link
G GPX1 glutathione peroxidase 1 increases expression
multiple interactions
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GPX1 mRNA
[sodium arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of GPX1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of GPX1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in decreased expression of GPX1 mRNA]; sodium arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GPX1 protein]; sodium arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GPX1 mRNA]
CTD PMID:32301004 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 increases localization ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA1 protein CTD PMID:19674091 NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 increases localization ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of GRIA2 protein CTD PMID:19674091 NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
JBrowse link
G GRIP1 glutamate receptor interacting protein 1 increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GRIP1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [GRIP1 protein binds to NR1I3 protein]
CTD PMID:24224465 PMID:25566086 NCBI chr12:66,347,431...67,069,338
Ensembl chr12:66,347,431...67,069,162
JBrowse link
G GSDMD gasdermin D multiple interactions EXP [lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of and results in increased cleavage of GSDMD protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of GSDMD protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of and results in increased cleavage of GSDMD protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of GSDMD protein] CTD PMID:34920032 NCBI chr 8:143,553,387...143,563,062
Ensembl chr 8:143,553,207...143,563,062
JBrowse link
G GSG1L GSG1 like multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSG1L mRNA] CTD PMID:25566086 NCBI chr16:27,787,528...28,063,714
Ensembl chr16:27,787,528...28,063,714
JBrowse link
G GSK3B glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Estradiol inhibits the reaction [ESR1 protein binds to GSK3B protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of GSK3B protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSK3B protein modified form
CTD PMID:24085292 PMID:26990689 PMID:30703377 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
JBrowse link
G GSR glutathione-disulfide reductase increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSR protein
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GSR mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GSR protein
CTD PMID:20061341 PMID:33434570 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSS glutathione synthetase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSS mRNA CTD PMID:20061341 NCBI chr20:34,928,432...34,956,027
Ensembl chr20:34,928,432...34,956,027
JBrowse link
G GSTA2 glutathione S-transferase alpha 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA2 mRNA CTD PMID:12446695 NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475
JBrowse link
G GSTA3 glutathione S-transferase alpha 3 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTA3 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of GSTA1 mRNA]]
CTD PMID:16243960 PMID:20061341 NCBI chr 6:52,896,646...52,909,698
Ensembl chr 6:52,896,639...52,909,698
JBrowse link
G GSTM1 glutathione S-transferase mu 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM1 mRNA CTD PMID:20061341 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
JBrowse link
G GSTM2 glutathione S-transferase mu 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM5 mRNA CTD PMID:20061341 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTM3 glutathione S-transferase mu 3 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM3 mRNA CTD PMID:20061341 NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038
JBrowse link
G GSTO1 glutathione S-transferase omega 1 increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTO1 mRNA
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of GSTO1 mRNA
CTD PMID:33434570 NCBI chr10:104,254,173...104,267,455
Ensembl chr10:104,235,356...104,267,459
JBrowse link
G GSTO2 glutathione S-transferase omega 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTO2 mRNA CTD PMID:33434570 NCBI chr10:104,269,184...104,304,950
Ensembl chr10:104,268,873...104,304,950
JBrowse link
G GSTP1 glutathione S-transferase pi 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTP1 protein CTD PMID:15863507 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA]
CTD PMID:25566086 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059
JBrowse link
G GYG1 glycogenin 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG1 mRNA] CTD PMID:25566086 NCBI chr 3:148,991,540...149,031,775
Ensembl chr 3:148,991,408...149,031,775
JBrowse link
G H19 H19 imprinted maternally expressed transcript decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H19 mRNA CTD PMID:25566086 NCBI chr11:1,995,176...2,001,466
Ensembl chr11:1,995,166...2,004,552
JBrowse link
G H2AC11 H2A clustered histone 11 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC22 mRNA CTD PMID:25566086 NCBI chr 6:27,133,043...27,133,535
Ensembl chr 6:27,133,043...27,133,535
JBrowse link
G H2AC12 H2A clustered histone 12 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC12 mRNA CTD PMID:25566086 NCBI chr 6:27,147,106...27,147,562
Ensembl chr 6:27,147,106...27,147,562
JBrowse link
G H2AC14 H2A clustered histone 14 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC13 mRNA CTD PMID:25566086 NCBI chr 6:27,814,302...27,814,777
Ensembl chr 6:27,814,302...27,814,777
JBrowse link
G H2AC15 H2A clustered histone 15 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC15 mRNA CTD PMID:25566086 NCBI chr 6:27,837,880...27,838,375
Ensembl chr 6:27,837,880...27,838,375
JBrowse link
G H2AC7 H2A clustered histone 7 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC7 mRNA CTD PMID:25566086 NCBI chr 6:26,198,784...26,199,293
Ensembl chr 6:26,198,784...26,199,293
JBrowse link
G H2AX H2A.X variant histone multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AX protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased expression of H2AX protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Etoposide results in increased expression of H2AX protein]
CTD PMID:17875725 PMID:21227924 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465
JBrowse link
G H4C16 H4 histone 16 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased acetylation of H4C16 protein] CTD PMID:15857753 NCBI chr12:14,770,720...14,771,131
Ensembl chr12:14,767,999...14,771,131
JBrowse link
G HAGHL hydroxyacylglutathione hydrolase like multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HAGHL mRNA CTD PMID:25566086 NCBI chr16:727,106...729,715
Ensembl chr16:726,936...735,525
JBrowse link
G HAX1 HCLS1 associated protein X-1 affects expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of HAX1 protein CTD PMID:19763263 NCBI chr 1:154,272,629...154,275,875
Ensembl chr 1:154,272,355...154,275,875
JBrowse link
G HDAC1 histone deacetylase 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin affects the localization of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Particulate Matter results in increased degradation of HDAC1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Vehicle Emissions results in increased degradation of HDAC1 protein] CTD PMID:17395887 PMID:17927689 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635
JBrowse link
G HDAC2 histone deacetylase 2 increases ubiquitination
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HDAC2 protein
[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Smoke results in increased degradation of and results in decreased expression of HDAC2 protein]; CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein]
CTD PMID:18421014 PMID:24973648 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308
JBrowse link
G HDAC6 histone deacetylase 6 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HDAC6 protein results in increased expression of ESRRA protein] CTD PMID:34524571 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982
JBrowse link
G HES1 hes family bHLH transcription factor 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HES1 mRNA] CTD PMID:25566086 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha decreases degradation
multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of HIF1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form
3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; [andrographolide co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HIF1A protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Oxygen deficiency] affects the expression of HIF1A protein; [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of HIF1A protein; [Formaldehyde co-treated with VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of HIF1A protein; [Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein; [VH298 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of HIF1A protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [[Apigenin co-treated with Oxygen deficiency] affects the expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [geldanamycin results in increased degradation of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [scutellarin results in decreased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of HIF1A protein; bruceine D inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Curcumin analog inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein modified form]; diallyl trisulfide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of HIF1A protein]; dictamnine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Digitoxin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; dihydrotanshinone I inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; genipin affects the reaction [[Oxygen deficiency co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the expression of HIF1A protein]; Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]]; Resveratrol inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of HIF1A protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]
CTD PMID:11980636 PMID:17764071 PMID:17973296 PMID:18682687 PMID:19254699 More... NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259
JBrowse link
G HIGD1B HIG1 hypoxia inducible domain family member 1B decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA]
CTD PMID:25566086 NCBI chr17:44,844,860...44,850,476
Ensembl chr17:44,846,353...44,850,476
JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cobaltous chloride results in decreased expression of HIPK2 protein] CTD PMID:19714248 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998
JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H2-AB1 mRNA] CTD PMID:25566086 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
increases ubiquitination
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in decreased expression of HMOX1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hemin results in decreased expression of HMOX1 protein]
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of HMOX1 mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of HMOX1 protein; [USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; [USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; Arsenic inhibits the reaction [[USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [[USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Hemin results in increased expression of HMOX1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]; HMOX1 protein inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 protein]; HMOX1 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA]; USP7 protein affects the reaction [Arsenic inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]]; USP7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of HMOX1 mRNA]
CTD PMID:12441344 PMID:18550526 PMID:18835339 PMID:25824035 PMID:30186748 More... NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetracaine results in decreased expression of HNRNPA1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Thapsigargin affects the localization of HNRNPA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tunicamycin affects the localization of HNRNPA1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HNRNPA1 mRNA
CTD PMID:23106379 PMID:34822839 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NSC606985 results in decreased expression of HNRNPK protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [PRKCD protein results in increased ubiquitination of HNRNPK protein] CTD PMID:19747914 NCBI chr 9:83,968,083...83,980,615
Ensembl chr 9:83,968,083...83,980,631
JBrowse link
G HOPX HOP homeobox multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HOPX mRNA CTD PMID:25566086 NCBI chr 4:56,647,998...56,681,706
Ensembl chr 4:56,647,989...56,681,877
JBrowse link
G HP haptoglobin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HP mRNA CTD PMID:20061341 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055
JBrowse link
G HR HR lysine demethylase and nuclear receptor corepressor multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA] CTD PMID:25566086 NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384
JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Progesterone results in increased expression of HSD11B2 mRNA] CTD PMID:15857753 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553
JBrowse link
G HSF1 heat shock transcription factor 1 increases activity
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of HSF1 protein
HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 mRNA]; HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBC mRNA]
CTD PMID:11893605 PMID:30186748 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720
JBrowse link
G HSF2 heat shock transcription factor 2 increases activity
increases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of HSF2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF2 protein
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF2 protein]
CTD PMID:11893605 PMID:15914627 NCBI chr 6:122,399,551...122,433,119
Ensembl chr 6:122,399,551...122,433,119
JBrowse link
G HSF4 heat shock transcription factor 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF4 protein
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSF4 protein]
CTD PMID:15914627 NCBI chr16:67,163,761...67,169,941
Ensembl chr16:67,164,681...67,169,945
JBrowse link
G HSP90AA1 heat shock protein 90 alpha family class A member 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSP90AA1 mRNA CTD PMID:25566086 NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A multiple interactions
increases expression
ISO PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A mRNA
CTD PMID:18331584 PMID:25566086 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1B mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1B protein CTD PMID:15525353 PMID:25566086 NCBI chr 6:31,827,738...31,830,254
Ensembl chr 6:31,827,738...31,830,254
JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 multiple interactions
increases expression
ISO
EXP
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 protein]
HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA4 mRNA]
CTD PMID:15914627 PMID:30186748 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA5 protein CTD PMID:19139269 PMID:21692457 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of HSPA8 mRNA CTD PMID:25566086 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in decreased expression of HSPA9 protein] CTD PMID:37353096 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [bufalin results in decreased expression of HSPB1 protein]
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPB1 protein]
CTD PMID:15914627 PMID:23091618 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
JBrowse link
G HSPB2 heat shock protein family B (small) member 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA]
CTD PMID:25566086 NCBI chr11:111,912,734...111,914,093
Ensembl chr11:111,912,734...111,914,093
JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPH1 mRNA CTD PMID:25566086 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388
JBrowse link
G HTRA2 HtrA serine peptidase 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HTRA2 protein CTD PMID:19763263 NCBI chr 2:74,529,405...74,533,556
Ensembl chr 2:74,529,596...74,533,350
JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
MG132 pretreatment decreases expression of protein in liver of intestinal ischemia/reperfusion rats
CTD
RGD
PMID:11698246 PMID:14572618 PMID:22079846 RGD:401794136 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615
JBrowse link
G IFNG interferon gamma multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
CTD PMID:15914627 PMID:19393675 PMID:23395999 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of IGF1R protein] CTD PMID:28711525 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G IGF2 insulin like growth factor 2 multiple interactions
decreases response to substance
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to IGF2 protein
CTD PMID:24055520 NCBI chr11:2,129,117...2,149,566
Ensembl chr11:2,129,112...2,158,391
JBrowse link
G IL18 interleukin 18 multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein]
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of IL18 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of IL18 protein]
CTD PMID:15178407 PMID:34920032 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
JBrowse link
G IL1A interleukin 1 alpha multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1A protein results in increased secretion of CCL2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IL1A mRNA
CTD PMID:11230753 PMID:15728660 PMID:20061341 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
JBrowse link
G IL1B interleukin 1 beta multiple interactions
decreases response to substance
EXP
ISO
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of IL1B protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of IL1B protein]; sodium arsenite inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased susceptibility to IL1B protein
CTD PMID:10541287 PMID:11835394 PMID:14581482 PMID:19393675 PMID:23395999 More... NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 increases expression
decreases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 protein
MG132 pretreatment decreases expression of TNFa, IL6 protein in serum of intestinal ischemia/reperfusion rats
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Chloroquine co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL6 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]
Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IL6 protein]
CTD
RGD
PMID:11893605 PMID:18457675 PMID:28134560 PMID:31806706 PMID:22079846 RGD:401794136 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IMPACT impact RWD domain protein increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IMPACT mRNA CTD PMID:25566086 NCBI chr18:24,426,670...24,453,531
Ensembl chr18:24,426,634...24,453,531
JBrowse link
G INAFM2 InaF motif containing 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of INAFM2 mRNA CTD PMID:25566086 NCBI chr15:40,323,692...40,326,715
Ensembl chr15:40,323,692...40,326,715
JBrowse link
G INS insulin multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [L-4F peptide inhibits the reaction [INS protein results in increased expression of HIF1A protein]] CTD PMID:22537771 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G INS-IGF2 INS-IGF2 readthrough multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [INS1 protein results in decreased expression of IRS1 protein] CTD PMID:24219910 NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209
JBrowse link
G INSL6 insulin like 6 multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of INSL6 mRNA] CTD PMID:25566086 NCBI chr 9:4,991,976...5,185,639
Ensembl chr 9:5,123,880...5,185,647
JBrowse link
G IRF8 interferon regulatory factor 8 decreases degradation ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of IRF8 protein CTD PMID:15837792 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606
JBrowse link
G IRS1 insulin receptor substrate 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [INS1 protein results in decreased expression of IRS1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in decreased expression of IRS1 protein] CTD PMID:24219910 PMID:32061799 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
JBrowse link
G IRX3 iroquois homeobox 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of IRX3 mRNA CTD PMID:25566086 NCBI chr16:54,283,304...54,286,787
Ensembl chr16:54,283,304...54,286,787
JBrowse link
G ITGAM integrin subunit alpha M multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of ITGAM protein] CTD PMID:20945414 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
JBrowse link
G ITGB1BP2 integrin subunit beta 1 binding protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ITGB1BP2 mRNA CTD PMID:25566086 NCBI chr  X:71,301,750...71,305,371
Ensembl chr  X:71,301,750...71,305,371
JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acrylamide results in decreased expression of ITPR3 protein] CTD PMID:37353096 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
JBrowse link
G IVL involucrin increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of IVL mRNA CTD PMID:25566086 NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KU-32 compound inhibits the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of JUN protein]
CTD PMID:23240583 PMID:23593480 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]] CTD PMID:17148446 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
JBrowse link
G KAT5 lysine acetyltransferase 5 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KAT5 protein results in increased acetylation of and results in increased degradation of SRSF2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of KAT5 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KAT5 protein
CTD PMID:21157427 PMID:28837777 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604
JBrowse link
G KATNB1 katanin regulatory subunit B1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KATNB1 mRNA CTD PMID:25566086 NCBI chr16:57,735,770...57,757,244
Ensembl chr16:57,735,739...57,757,244
JBrowse link
G KBTBD11 kelch repeat and BTB domain containing 11 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KBTBD11 mRNA CTD PMID:25566086 NCBI chr 8:1,973,677...2,006,936
Ensembl chr 8:1,973,677...2,006,936
JBrowse link
G KCNG2 potassium voltage-gated channel modifier subfamily G member 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KCNG2 mRNA CTD PMID:25566086 NCBI chr18:79,797,938...79,900,100
Ensembl chr18:79,797,938...79,900,184
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of KCNH2 protein] CTD PMID:28521025 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNIP3 potassium voltage-gated channel interacting protein 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein] CTD PMID:30503815 NCBI chr 2:95,297,347...95,386,077
Ensembl chr 2:95,297,327...95,386,077
JBrowse link
G KCNN2 potassium calcium-activated channel subfamily N member 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [FBXO32 protein results in decreased expression of KCNN2 protein] CTD PMID:30635400 NCBI chr 5:114,055,978...114,496,496
Ensembl chr 5:114,055,926...114,496,500
JBrowse link
G KDM1A lysine demethylase 1A multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SP2509 results in decreased stability of KDM1A protein] CTD PMID:29581250 NCBI chr 1:23,019,468...23,083,689
Ensembl chr 1:23,019,443...23,083,689
JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO [2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein] CTD PMID:18512965 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G KIF1A kinesin family member 1A increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA]
CTD PMID:25566086 NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293
JBrowse link
G KIF1B kinesin family member 1B increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1B mRNA CTD PMID:25566086 NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
JBrowse link
G KIF20A kinesin family member 20A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF20A mRNA CTD PMID:20061341 NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
JBrowse link
G KIF4A kinesin family member 4A decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KIF4 mRNA CTD PMID:20061341 NCBI chr  X:70,290,104...70,420,886
Ensembl chr  X:70,290,104...70,420,886
JBrowse link
G KLF2 KLF transcription factor 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TRAF2 protein results in decreased expression of KLF2 protein] CTD PMID:35635602 NCBI chr19:16,324,826...16,328,685
Ensembl chr19:16,324,826...16,328,685
JBrowse link
G KLF6 KLF transcription factor 6 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KLF6 mRNA CTD PMID:31806706 NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
JBrowse link
G KLHL6 kelch like family member 6 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KLHL6 mRNA] CTD PMID:25566086 NCBI chr 3:183,487,551...183,555,706
Ensembl chr 3:183,487,551...183,555,706
JBrowse link
G KLK2 kallikrein related peptidase 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Testosterone results in increased expression of KLK2 mRNA] CTD PMID:12376534 NCBI chr19:50,873,439...50,880,567
Ensembl chr19:50,861,568...50,880,567
JBrowse link
G KNSTRN kinetochore localized astrin (SPAG5) binding protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KNSTRN mRNA CTD PMID:20061341 NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288
JBrowse link
G KRAS KRAS proto-oncogene, GTPase increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KRAS mRNA CTD PMID:31806706 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936
JBrowse link
G KRT5 keratin 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [Diacetyl affects the expression of and affects the ubiquitination of KRT5 protein] CTD PMID:32112875 NCBI chr12:52,514,575...52,520,394
Ensembl chr12:52,514,575...52,520,530
JBrowse link
G KY kyphoscoliosis peptidase multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA CTD PMID:25566086 NCBI chr 3:134,599,923...134,651,022
Ensembl chr 3:134,599,923...134,651,636
JBrowse link
G LAT2 linker for activation of T cells family member 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate results in decreased expression of LAT2 protein] CTD PMID:23001822 NCBI chr 7:74,210,006...74,229,834
Ensembl chr 7:74,199,652...74,229,834
JBrowse link
G LDB3 LIM domain binding 3 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LDB3 mRNA] CTD PMID:25566086 NCBI chr10:86,666,788...86,736,072
Ensembl chr10:86,666,785...86,736,072
JBrowse link
G LGALS1 galectin 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LGALS1 mRNA CTD PMID:25566086 NCBI chr22:37,675,636...37,679,802
Ensembl chr22:37,675,636...37,679,802
JBrowse link
G LMO7 LIM domain 7 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LMO7 mRNA] CTD PMID:25566086 NCBI chr13:75,620,434...75,859,870
Ensembl chr13:75,620,434...75,859,870
JBrowse link
G LNX1 ligand of numb-protein X 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LNX1 mRNA CTD PMID:20061341 NCBI chr 4:53,459,301...53,652,477
Ensembl chr 4:53,459,301...53,701,405
JBrowse link
G LPIN1 lipin 1 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TGFB1 protein results in decreased expression of LPIN1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of LPIN1 protein
CTD PMID:27345520 NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409
JBrowse link
G LRRC10 leucine rich repeat containing 10 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC10 mRNA; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA]
CTD PMID:25566086 NCBI chr12:69,608,564...69,610,907
Ensembl chr12:69,608,564...69,610,907
JBrowse link
G LRRC75A leucine rich repeat containing 75A multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC75A mRNA CTD PMID:25566086 NCBI chr17:16,441,577...16,492,193
Ensembl chr17:16,441,577...16,492,193
JBrowse link
G LRRK2 leucine rich repeat kinase 2 increases ubiquitination EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of LRRK2 protein CTD PMID:24942733 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G LUC7L LUC7 like multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of LUC7L mRNA CTD PMID:25566086 NCBI chr16:188,990...229,449
Ensembl chr16:188,969...229,463
JBrowse link
G LXN latexin decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA]
CTD PMID:25566086 NCBI chr 3:158,666,414...158,672,648
Ensembl chr 3:158,645,822...158,672,648
JBrowse link
G MAF1 MAF1 homolog, negative regulator of RNA polymerase III multiple interactions EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Sirolimus] results in decreased degradation of MAF1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of and results in decreased degradation of MAF1 protein; CUL2 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MAF1 protein] CTD PMID:31645432 NCBI chr 8:144,104,461...144,107,611
Ensembl chr 8:144,104,420...144,107,611
JBrowse link
G MALAT1 metastasis associated lung adenocarcinoma transcript 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MALAT1 mRNA affects the reaction [sodium arsenite results in increased expression of HIF1A protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [MALAT1 mRNA promotes the reaction [sodium arsenite results in increased expression of EPAS1 protein]]; MALAT1 mRNA promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]; MALAT1 mRNA promotes the reaction [sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein]] CTD PMID:26735578 PMID:27287256 NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,640...65,508,073
JBrowse link
G MAP1B microtubule associated protein 1B increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA]
CTD PMID:25566086 NCBI chr 5:72,107,475...72,209,565
Ensembl chr 5:72,107,234...72,209,565
JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1LC3B protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trovafloxacin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; MAP1LC3B protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of NFKBIA protein]
CTD PMID:24085292 PMID:26409479 PMID:33609687 NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:25780039 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:25780039 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPK8 mitogen-activated protein kinase 8 increases phosphorylation
decreases response to substance
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of MAPK8 protein
MAPK8 gene mutant form results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]
CTD PMID:18463101 PMID:23593480 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions ISO MAPK9 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA] CTD PMID:23593480 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G MAPKAPK2 MAPK activated protein kinase 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Benzo(a)pyrene results in increased degradation of MAPKAPK2 protein] CTD PMID:35427736 NCBI chr 1:206,684,905...206,734,281
Ensembl chr 1:206,684,905...206,734,281
JBrowse link
G MARCHF6 membrane associated ring-CH-type finger 6 increases stability EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of MARCHF6 protein CTD PMID:30545937 NCBI chr 5:10,353,695...10,440,388
Ensembl chr 5:10,353,695...10,440,388
JBrowse link
G MASP1 MBL associated serine protease 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MASP1 mRNA CTD PMID:25566086 NCBI chr 3:187,217,282...187,291,737
Ensembl chr 3:187,217,282...187,291,980
JBrowse link
G MB myoglobin decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA]
CTD PMID:25566086 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
JBrowse link
G MBD2 methyl-CpG binding domain protein 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MBD2 protein] CTD PMID:23395981 NCBI chr18:54,151,606...54,224,669
Ensembl chr18:54,151,606...54,224,669
JBrowse link
G MBD3 methyl-CpG binding domain protein 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MBD3 protein] CTD PMID:23395981 NCBI chr19:1,573,596...1,592,865
Ensembl chr19:1,573,596...1,592,865
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member multiple interactions
increases expression
decreases degradation
increases ubiquitination
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Resveratrol co-treated with Clofarabine] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[WEHI-539 co-treated with venetoclax] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Clofarabine promotes the reaction [Resveratrol results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Daunorubicin results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Quercetin results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Resveratrol promotes the reaction [Clofarabine results in decreased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [USP7 protein affects the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Resveratrol co-treated with Clofarabine] results in increased expression of MCL1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MCL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of MCL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of MCL1 protein
CTD PMID:16109713 PMID:17553788 PMID:20802529 PMID:21750559 PMID:21933852 More... NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
JBrowse link
G MCM5 minichromosome maintenance complex component 5 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MCM5 mRNA CTD PMID:25566086 NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431
JBrowse link
G MDM2 MDM2 proto-oncogene increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MDM2 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]
CTD PMID:17575151 PMID:20061341 NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544
JBrowse link
G MECP2 methyl-CpG binding protein 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of MECP2 protein] CTD PMID:23395981 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103
JBrowse link
G MGARP mitochondria localized glutamic acid rich protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGARP mRNA CTD PMID:25566086 NCBI chr 4:139,266,165...139,280,225
Ensembl chr 4:139,266,165...139,280,225
JBrowse link
G MGLL monoglyceride lipase decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGLL mRNA CTD PMID:25566086 NCBI chr 3:127,689,066...127,823,185
Ensembl chr 3:127,689,062...128,052,190
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tamoxifen results in increased degradation of MGMT protein] CTD PMID:17597106 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MGST1 mRNA CTD PMID:20061341 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MIR122 microRNA 122 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MIR122 mRNA CTD PMID:31806706 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
JBrowse link
G MIR146A microRNA 146a decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MIR146A CTD PMID:32392329 NCBI chr 5:160,485,352...160,485,450
Ensembl chr 5:160,485,352...160,485,450
JBrowse link
G MITF melanocyte inducing transcription factor multiple interactions
decreases expression
ISO
EXP
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MITF mRNA
CTD PMID:29486182 PMID:31806706 NCBI chr 3:69,739,464...69,968,332
Ensembl chr 3:69,739,456...69,968,336
JBrowse link
G MLKL mixed lineage kinase domain like pseudokinase increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA]
CTD PMID:25566086 NCBI chr16:74,671,855...74,700,862
Ensembl chr16:74,671,855...74,700,960
JBrowse link
G MLLT11 MLLT11 transcription factor 7 cofactor increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLLT11 mRNA CTD PMID:25566086 NCBI chr 1:151,060,397...151,069,544
Ensembl chr 1:151,060,397...151,069,544
JBrowse link
G MMP13 matrix metallopeptidase 13 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [halofuginone results in increased expression of MMP13 mRNA] CTD PMID:16489207 NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732
JBrowse link
G MMP23B matrix metallopeptidase 23B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 mRNA CTD PMID:25566086 NCBI chr 1:1,632,173...1,634,654
Ensembl chr 1:1,632,163...1,635,263
JBrowse link
G MMP9 matrix metallopeptidase 9 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [butein results in decreased expression of MMP9 protein] CTD PMID:15728660 PMID:20696233 PMID:24613819 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
JBrowse link
G MOCOS molybdenum cofactor sulfurase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCOS mRNA CTD PMID:20061341 PMID:25566086 NCBI chr18:36,187,497...36,272,157
Ensembl chr18:36,187,497...36,272,157
JBrowse link
G MOCS1 molybdenum cofactor synthesis 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA]
CTD PMID:25566086 NCBI chr 6:39,904,170...39,934,462
Ensembl chr 6:39,899,578...39,934,551
JBrowse link
G MOCS2 molybdenum cofactor synthesis 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS2 mRNA CTD PMID:25566086 NCBI chr 5:53,095,679...53,109,757
Ensembl chr 5:53,095,679...53,110,063
JBrowse link
G MT3 metallothionein 3 multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MT3 mRNA] CTD PMID:25566086 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G MTERF3 mitochondrial transcription termination factor 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of MTERF3 protein] CTD PMID:35904214 NCBI chr 8:96,239,398...96,261,613
Ensembl chr 8:96,239,398...96,261,610
JBrowse link
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenic trioxide results in increased degradation of MTHFD1 protein] CTD PMID:28265077 NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
JBrowse link
G MTOR mechanistic target of rapamycin kinase increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MTOR protein CTD PMID:25897075 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MTTP microsomal triglyceride transfer protein multiple interactions
increases expression
EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Chloroquine] results in increased expression of MTTP protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MTTP protein
CTD PMID:34516972 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997
JBrowse link
G MTUS1 microtubule associated scaffold protein 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MTUS1 mRNA CTD PMID:25566086 NCBI chr 8:17,643,802...17,801,521
Ensembl chr 8:17,643,795...17,801,094
JBrowse link
G MUC1 mucin 1, cell surface associated multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [MUC1 affects the expression of EGFR protein] CTD PMID:22457794 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased secretion of MUC5AC protein] CTD PMID:22766066 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G MYBPC3 myosin binding protein C3 decreases expression
affects response to substance
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPC3 mRNA
MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of BOK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CAV1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CCNB1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDH3 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CDK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of CKB mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of EGFL7 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of FAHD1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of G0S2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of GPR146 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC12 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC13 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC15 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC22 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of H2AC7 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HAGHL mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of HOPX mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KBTBD11 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of KY mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LGALS1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC10 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of LRRC75A mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MCM5 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MMP23 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYL12B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYLK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of NRM mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PBK mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PDLIM4 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLEKHG2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPARGC1B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPP1R3G mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ROBO4 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of SYNPO mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TK1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176A mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TRIB2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ZFYVE21 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of ATG12 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of EIF2AK2 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of FAM13B mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of GADD45G mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of HSPA8 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of LUC7L mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of NRIP3 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SF1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SWT1 mRNA; [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of UFD1 mRNA; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACAA2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ACTC1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ADSS1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of APH1A mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ARG1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ART3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of C1QB mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAR14 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CAVIN1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CENPA mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CHRM2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CKMT2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CLIP4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CMYA5 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of CORIN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGLN3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of FBXO10 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GSG1L mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GUCY1A1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of GYG1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of H2-AB1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HES1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HIGD1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HSPB2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of KLHL6 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LDB3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LMO7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LRRC10 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of LXN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MB mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPC3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PIP5K1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLAC8 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SH3KBP1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPON2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UNC13C mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ZBTB8B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CD14 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of CLDN4 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DNMT3L mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of DYNC1H1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of INSL6 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of KIF1A mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MAP1B mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MLKL mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MOCS1 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MT3 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDPN mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SPRR2G mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SYBU mRNA]; MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA]
CTD PMID:25566086 NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
JBrowse link
G MYBPHL myosin binding protein H like decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYBPHL mRNA]
CTD PMID:25566086 NCBI chr 1:109,292,365...109,307,011
Ensembl chr 1:109,292,365...109,307,011
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of MYC protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Drugs, Chinese Herbal results in decreased expression of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in increased degradation of MYC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in decreased expression of MYC protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein
[arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of MYC protein; [arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of MYC protein modified form; arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MYC protein]; FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]; NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]
CTD PMID:20046830 PMID:20945414 PMID:21472727 PMID:23593480 PMID:24457827 More... NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYH6 myosin heavy chain 6 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYH6 mRNA CTD PMID:25566086 NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
JBrowse link
G MYL1 myosin light chain 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL1 mRNA] CTD PMID:25566086 NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174
JBrowse link
G MYL12B myosin light chain 12B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYL12B mRNA CTD PMID:25566086 NCBI chr18:3,262,133...3,278,461
Ensembl chr18:3,261,479...3,278,461
JBrowse link
G MYL7 myosin light chain 7 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYL7 mRNA]
CTD PMID:25566086 NCBI chr 7:44,138,864...44,141,332
Ensembl chr 7:44,138,864...44,141,332
JBrowse link
G MYLK myosin light chain kinase multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of MYLK mRNA CTD PMID:25566086 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
JBrowse link
G MYLK3 myosin light chain kinase 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYLK3 mRNA CTD PMID:25566086 NCBI chr16:46,702,282...46,763,246
Ensembl chr16:46,702,282...46,790,407
JBrowse link
G MYO5B myosin VB decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYO5B mRNA]
CTD PMID:25566086 NCBI chr18:49,822,789...50,195,147
Ensembl chr18:49,822,789...50,195,164
JBrowse link
G MYZAP myocardial zonula adherens protein decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MYZAP mRNA]
CTD PMID:25566086 NCBI chr15:57,591,904...57,685,364
Ensembl chr15:57,591,904...57,685,364
JBrowse link
G NACAD NAC alpha domain containing decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NACAD mRNA]
CTD PMID:25566086 NCBI chr 7:45,080,437...45,088,969
Ensembl chr 7:45,080,437...45,088,969
JBrowse link
G NANOG Nanog homeobox multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of NANOG protein] CTD PMID:23651583 NCBI chr12:7,789,402...7,799,146
Ensembl chr12:7,787,794...7,799,146
JBrowse link
G NAPB NSF attachment protein beta increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NAPB mRNA CTD PMID:25566086 NCBI chr20:23,374,522...23,421,488
Ensembl chr20:23,374,519...23,421,519
JBrowse link
G NCOA3 nuclear receptor coactivator 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased degradation of NCOA3 protein] CTD PMID:16456540 NCBI chr20:47,501,887...47,656,872
Ensembl chr20:47,501,887...47,656,877
JBrowse link
G NCOR1 nuclear receptor corepressor 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of NCOR1 protein CTD PMID:15857753 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185
JBrowse link
G NCOR2 nuclear receptor corepressor 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of NCOR2 protein CTD PMID:15857753 NCBI chr12:124,324,415...124,567,612
Ensembl chr12:124,324,415...124,567,612
JBrowse link
G NDFIP1 Nedd4 family interacting protein 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] CTD PMID:26300475 NCBI chr 5:142,108,779...142,154,440
Ensembl chr 5:142,108,779...142,154,440
JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NEDD4L mRNA CTD PMID:20061341 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540
JBrowse link
G NEURL2 neuralized E3 ubiquitin protein ligase 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NEURL2 mRNA CTD PMID:25566086 NCBI chr20:45,888,634...45,891,208
Ensembl chr20:45,888,625...45,891,208
JBrowse link
G NFAT5 nuclear factor of activated T cells 5 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in increased degradation of NFAT5 protein] CTD PMID:17105721 NCBI chr16:69,565,966...69,704,654
Ensembl chr16:69,565,094...69,704,666
JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 decreases degradation
multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NFE2L1 protein alternative form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Glucose results in increased expression of NFE2L1 protein]; Glucose promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L1 protein]; Metformin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L1 protein]
CTD PMID:28549828 PMID:33838154 NCBI chr17:48,048,359...48,061,545
Ensembl chr17:48,048,329...48,061,545
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
increases ubiquitination
decreases degradation
increases expression
increases activity
EXP
ISO
2-tert-butyl-4-quinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; 2-tert-butylhydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of and affects the localization of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Homocysteine results in decreased phosphorylation of and results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Glucose results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to NQO1 promoter]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforaphane results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased stability of and results in increased ubiquitination of NFE2L2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased localization of and results in increased activity of NFE2L2 protein; Curcumin inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]]; cyanoginosin LR inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]; hydroquinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]; Metformin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GCLC mRNA]; NFE2L2 protein promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HMOX1 mRNA]; quinone inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NFE2L2 protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NFE2L2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [triptolide affects the expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [N-acetylsphingosine results in decreased localization of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptolide results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sulforaphane results in increased activity of NFE2L2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of NFE2L2 protein
[2-tert-butylhydroquinone co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of and results in increased ubiquitination of NFE2L2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 2-tert-butylhydroquinone] results in increased expression of NFE2L2 protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Cycloheximide] results in increased expression of NFE2L2 protein; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Particulate Matter analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Vehicle Emissions analog results in increased expression of NFE2L2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [2-tert-butylhydroquinone results in increased ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cadmium Chloride affects the ubiquitination of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to KEAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and affects the localization of NFE2L2 protein; Exenatide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NFE2L2 protein]
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein] which results in increased expression of CBR3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFE2L2 protein
CTD PMID:12441344 PMID:12446695 PMID:14510636 PMID:15319326 PMID:15322212 More... NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of [NFKB1 protein binds to RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein]; FBXW7 protein promotes the reaction [NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]]; NFKB1 gene mutant form inhibits the reaction [arsenite inhibits the reaction [Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of MYC protein]]]
CTD PMID:11543732 PMID:14527959 PMID:14581482 PMID:16026644 PMID:24457827 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions
increases expression
increases phosphorylation
EXP
ISO
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with TNF protein] results in increased phosphorylation of NFKBIA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [evodiamine results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [osthol results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Deoxycholic Acid results in increased phosphorylation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased degradation of NFKBIA protein; MAP1LC3B protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of NFKBIA protein]; sodium arsenite inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with IL1B protein] results in increased expression of and results in increased phosphorylation of NFKBIA protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]
MG132 pretreatment increases expression of protein in liver of intestinal ischemia/reperfusion rats
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NFKBIA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased phosphorylation of NFKBIA protein]
CTD
RGD
PMID:11543732 PMID:11698246 PMID:11835394 PMID:11923223 PMID:12185005 More... RGD:401794136 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
JBrowse link
G NFKBIB NFKB inhibitor beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIB protein] CTD PMID:11543732 NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893
JBrowse link
G NFKBIE NFKB inhibitor epsilon multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIE protein] CTD PMID:12185005 NCBI chr 6:44,258,166...44,265,551
Ensembl chr 6:44,258,166...44,265,788
JBrowse link
G NGF nerve growth factor multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NGF mRNA] CTD PMID:25566086 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
JBrowse link
G NGLY1 N-glycanase 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NGLY1 protein binds to UBXN1 protein] CTD PMID:15362974 NCBI chr 3:25,718,944...25,790,039
Ensembl chr 3:25,718,944...25,790,039
JBrowse link
G NIPSNAP2 nipsnap homolog 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NIPSNAP2 mRNA]
CTD PMID:25566086 NCBI chr 7:55,964,585...56,000,179
Ensembl chr 7:55,951,793...56,000,181
JBrowse link
G NME3 NME/NM23 nucleoside diphosphate kinase 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NME3 mRNA CTD PMID:25566086 NCBI chr16:1,770,320...1,771,543
Ensembl chr16:1,770,320...1,771,561
JBrowse link
G NMRK2 nicotinamide riboside kinase 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NMRK2 mRNA]
CTD PMID:25566086 NCBI chr19:3,933,069...3,942,416
Ensembl chr19:3,933,069...3,942,416
JBrowse link
G NOL3 nucleolar protein 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [Doxorubicin results in increased degradation of NOL3 protein] CTD PMID:19139834 NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [zinc protoporphyrin inhibits the reaction [Peptidoglycan results in increased expression of NOS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of NOS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NOS2 protein
CTD PMID:11923223 PMID:12628480 PMID:12721113 PMID:17891158 PMID:19376148 More... NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NOS3 nitric oxide synthase 3 decreases degradation
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of NOS3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOS3 protein
CTD PMID:20229525 PMID:20675566 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
JBrowse link
G NOTCH1 notch receptor 1 increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOTCH1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptonide results in increased degradation of NOTCH1 protein]
CTD PMID:24497960 PMID:24801890 PMID:31597699 PMID:31866380 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Lead results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide promotes the reaction [Copper results in decreased expression of NQO1 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NQO1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NQO1 protein
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of NQO1 mRNA; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Hemin] results in increased expression of NQO1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NFE2L2 protein binds to NQO1 promoter]
CTD PMID:16243960 PMID:20061341 PMID:22606287 PMID:30186748 PMID:33434570 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 multiple interactions
increases ubiquitination
decreases activity
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [DNAJC7 protein results in increased expression of NR1I3 protein]; NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of DNAJC7 protein]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of NR1I3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of NR1I3 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in increased activity of NR1I3 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [GRIP1 protein binds to NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phenobarbital affects the localization of NR1I3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NR1I3 protein
CTD PMID:24224465 PMID:24789201 NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NR3C1 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tubacin results in decreased expression of and results in increased degradation of NR3C1 mRNA]
CTD PMID:20619282 PMID:31778773 PMID:31806706 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
JBrowse link
G NRG1 neuregulin 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KU-32 compound inhibits the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NRG1 protein results in increased expression of and results in increased phosphorylation of JUN protein] CTD PMID:23240583 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
G NRIP3 nuclear receptor interacting protein 3 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of NRIP3 mRNA CTD PMID:25566086 NCBI chr11:8,980,576...9,004,505
Ensembl chr11:8,965,682...9,005,288
JBrowse link
G NRM nurim multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of NRM mRNA CTD PMID:25566086 NCBI chr 6:30,688,049...30,691,420
Ensembl chr 6:30,688,047...30,691,420
JBrowse link
G NSD2 nuclear receptor binding SET domain protein 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [3-deazaneplanocin results in increased degradation of NSD2 protein] CTD PMID:32001260 NCBI chr 4:1,871,393...1,982,192
Ensembl chr 4:1,871,393...1,982,207
JBrowse link
G NUF2 NUF2 component of NDC80 kinetochore complex decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NUF2 mRNA CTD PMID:20061341 NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764
JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NUPR1 mRNA CTD PMID:31806706 NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008
JBrowse link
G OGG1 8-oxoguanine DNA glycosylase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TH5487 inhibits the reaction [TGFB1 protein results in increased expression of OGG1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [TGFB1 protein results in increased expression of OGG1 protein] CTD PMID:35654123 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of OPA1 protein alternative form CTD PMID:20678484 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811
JBrowse link
G OPRD1 opioid receptor delta 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ARL6IP5 mutant form inhibits the reaction [Morphine results in increased expression of OPRD1 protein]] CTD PMID:21600884 NCBI chr 1:28,812,170...28,871,267
Ensembl chr 1:28,812,170...28,871,267
JBrowse link
G OSGIN1 oxidative stress induced growth inhibitor 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of OSGIN1 mRNA CTD PMID:20061341 PMID:25566086 NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
JBrowse link
G P2RX6 purinergic receptor P2X 6 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of P2RX6 mRNA CTD PMID:20061341 NCBI chr22:21,009,799...21,028,008
Ensembl chr22:21,009,808...21,028,013
JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions
decreases response to substance
ISO
EXP
PARK7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HSPA1A protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Paraquat results in increased sulfation of and results in increased oxidation of PARK7 protein]
PARK7 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
CTD PMID:18331584 PMID:26409479 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 increases cleavage ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein CTD PMID:15498850 PMID:16051428 PMID:18790767 PMID:20100472 PMID:34418242 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PAX2 paired box 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PAX2 mRNA CTD PMID:25566086 NCBI chr10:100,735,396...100,829,944
Ensembl chr10:100,735,396...100,829,944
JBrowse link
G PBK PDZ binding kinase multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PBK mRNA CTD PMID:25566086 NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
JBrowse link
G PCDH7 protocadherin 7 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PCDH7 mRNA]
CTD PMID:25566086 NCBI chr 4:30,720,369...31,146,800
Ensembl chr 4:30,720,369...31,146,805
JBrowse link
G PDCD6IP programmed cell death 6 interacting protein increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDCD6IP protein CTD PMID:21692457 NCBI chr 3:33,798,630...33,869,703
Ensembl chr 3:33,798,571...33,869,707
JBrowse link
G PDGFB platelet derived growth factor subunit B multiple interactions
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1A co-treated with PDGFB] results in increased secretion of MMP9 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDGFB mRNA
CTD PMID:15728660 PMID:25566086 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
JBrowse link
G PDK1 pyruvate dehydrogenase kinase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDK1 mRNA]
CTD PMID:25566086 NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
JBrowse link
G PDLIM4 PDZ and LIM domain 4 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PDLIM4 mRNA CTD PMID:25566086 NCBI chr 5:132,257,696...132,273,454
Ensembl chr 5:132,257,696...132,273,454
JBrowse link
G PDLIM5 PDZ and LIM domain 5 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDLIM5 mRNA]
CTD PMID:25566086 NCBI chr 4:94,451,942...94,668,223
Ensembl chr 4:94,451,857...94,668,227
JBrowse link
G PDPN podoplanin multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PDPN mRNA] CTD PMID:25566086 NCBI chr 1:13,583,757...13,617,957
Ensembl chr 1:13,583,465...13,617,957
JBrowse link
G PDXP pyridoxal phosphatase decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PDXP mRNA CTD PMID:25566086 NCBI chr22:37,658,723...37,666,932
Ensembl chr22:37,658,723...37,666,932
JBrowse link
G PDYN prodynorphin decreases secretion ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased secretion of PDYN protein alternative form CTD PMID:17670969 NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285
JBrowse link
G PERM1 PPARGC1 and ESRR induced regulator, muscle 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PERM1 mRNA]
CTD PMID:25566086 NCBI chr 1:975,198...982,093
Ensembl chr 1:975,198...982,117
JBrowse link
G PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PFKFB3 protein CTD PMID:19448625 NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644
JBrowse link
G PFKP phosphofructokinase, platelet decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PFKP mRNA]
CTD PMID:25566086 NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718
JBrowse link
G PGR progesterone receptor increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PGR protein CTD PMID:15218360 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 multiple interactions EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of PIN1 protein] CTD PMID:30093655 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689
JBrowse link
G PINK1 PTEN induced kinase 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[ponasterone A results in increased expression of PINK1 protein] which results in decreased expression of FIS1 protein] CTD PMID:20164189 NCBI chr 1:20,633,458...20,651,511
Ensembl chr 1:20,633,458...20,651,511
JBrowse link
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PIP5K1B mRNA] CTD PMID:25566086 NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176
JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [STA 9090 inhibits the reaction [PKD1 gene mutant form results in increased expression of BRD4 protein]] CTD PMID:25877301 NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898
JBrowse link
G PKIG cAMP-dependent protein kinase inhibitor gamma decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PKIG mRNA CTD PMID:25566086 NCBI chr20:44,531,875...44,619,037
Ensembl chr20:44,531,785...44,624,247
JBrowse link
G PLAC8 placenta associated 8 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLAC8 mRNA] CTD PMID:25566086 NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,090,048...83,137,075
JBrowse link
G PLEKHA6 pleckstrin homology domain containing A6 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLEKHA6 mRNA CTD PMID:25566086 NCBI chr 1:204,218,853...204,378,168
Ensembl chr 1:204,218,853...204,378,214
JBrowse link
G PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLEKHG2 mRNA CTD PMID:25566086 NCBI chr19:39,412,669...39,428,415
Ensembl chr19:39,412,669...39,428,415
JBrowse link
G PLK1 polo like kinase 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PLK1 mRNA CTD PMID:25566086 NCBI chr16:23,678,889...23,690,367
Ensembl chr16:23,677,656...23,690,367
JBrowse link
G PLN phospholamban decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLN mRNA CTD PMID:25566086 NCBI chr 6:118,548,296...118,561,716
Ensembl chr 6:118,548,296...118,561,716
JBrowse link
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLOD3 protein CTD PMID:21692457 NCBI chr 7:101,205,984...101,217,581
Ensembl chr 7:101,205,977...101,218,420
JBrowse link
G PLVAP plasmalemma vesicle associated protein decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PLVAP mRNA CTD PMID:25566086 NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,342
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 decreases degradation
increases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PMAIP1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA
MAPK8 affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]; MAPK9 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PMAIP1 mRNA]
CTD PMID:20802529 PMID:23593480 PMID:31806706 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305
JBrowse link
G PML PML nuclear body scaffold decreases degradation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PML protein modified form CTD PMID:26049103 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PNPLA3 mRNA CTD PMID:25566086 NCBI chr22:43,923,805...43,947,582
Ensembl chr22:43,923,792...43,964,488
JBrowse link
G POU5F1 POU class 5 homeobox 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of POU5F1 protein CTD PMID:24497960 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma increases activity
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of PPARG protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of PPARG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [rosiglitazone results in decreased expression of PPARG protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of PPARG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [alitretinoin results in increased activity of PPARG protein]
CTD PMID:15707588 PMID:18555852 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PPARGC1A PPARG coactivator 1 alpha decreases degradation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PPARGC1A protein CTD PMID:20860658 NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
JBrowse link
G PPARGC1B PPARG coactivator 1 beta multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPARGC1B mRNA CTD PMID:25566086 NCBI chr 5:149,730,310...149,857,959
Ensembl chr 5:149,730,298...149,855,022
JBrowse link
G PPIA peptidylprolyl isomerase A decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPIA mRNA CTD PMID:15857753 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564
JBrowse link
G PPL periplakin increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PPL mRNA CTD PMID:20061341 NCBI chr16:4,882,507...4,937,148
Ensembl chr16:4,882,507...4,960,741
JBrowse link
G PPP1R14C protein phosphatase 1 regulatory inhibitor subunit 14C decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PPP1R14C mRNA]
CTD PMID:25566086 NCBI chr 6:150,143,044...150,250,392
Ensembl chr 6:150,143,044...150,250,392
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A increases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PPP1R15A mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of PPP1R15A protein]
CTD PMID:19135031 PMID:25566086 PMID:29109149 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
JBrowse link
G PPP1R3G protein phosphatase 1 regulatory subunit 3G multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of PPP1R3G mRNA CTD PMID:25566086 NCBI chr 6:5,085,341...5,089,487
Ensembl chr 6:5,085,341...5,089,487
JBrowse link
G PRC1 protein regulator of cytokinesis 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRC1 mRNA]
CTD PMID:25566086 NCBI chr15:90,966,040...90,994,535
Ensembl chr15:90,966,040...90,995,629
JBrowse link
G PRDX1 peroxiredoxin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PRDX1 mRNA CTD PMID:20061341 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PRKCB protein kinase C beta multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein] CTD PMID:17644113 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611
JBrowse link
G PRKCD protein kinase C delta multiple interactions
increases phosphorylation
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NSC606985 results in increased activity of and results in increased cleavage of PRKCD protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [PRKCD protein results in increased ubiquitination of HNRNPK protein]; Glutathione inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of PRKCD protein] CTD PMID:15707588 PMID:19662097 PMID:19747914 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
JBrowse link
G PRKCSH PRKCSH beta subunit of glucosidase II increases response to substance ISO PRKCSH gene mutant form results in increased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD PMID:21685914 NCBI chr19:11,435,635...11,450,968
Ensembl chr19:11,435,284...11,450,968
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase multiple interactions
affects expression
decreases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [PRKN protein results in decreased expression of SLC11A2 protein alternative form]; Tretinoin affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of PRKN protein alternative form]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN mRNA
CTD PMID:18586549 PMID:20089134 PMID:28673964 PMID:28688199 NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
JBrowse link
G PSEN1 presenilin 1 multiple interactions EXP [PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein] CTD PMID:22302987 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691
JBrowse link
G PSMA1 proteasome 20S subunit alpha 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA1 mRNA CTD PMID:31806706 NCBI chr11:14,504,876...14,643,662
Ensembl chr11:14,504,874...14,643,635
JBrowse link
G PSMA2 proteasome 20S subunit alpha 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA2 mRNA CTD PMID:31806706 NCBI chr 7:42,916,861...42,932,174
Ensembl chr 7:42,916,828...42,932,185
JBrowse link
G PSMA3 proteasome 20S subunit alpha 3 increases expression ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA3 mRNA CTD PMID:15525353 PMID:31806706 NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012
JBrowse link
G PSMA4 proteasome 20S subunit alpha 4 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA4 mRNA CTD PMID:31806706 NCBI chr15:78,540,405...78,552,417
Ensembl chr15:78,540,405...78,552,417
JBrowse link
G PSMA5 proteasome 20S subunit alpha 5 increases expression ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA5 mRNA CTD PMID:15525353 PMID:31806706 NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448
JBrowse link
G PSMA6 proteasome 20S subunit alpha 6 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA6 mRNA CTD PMID:31806706 NCBI chr14:35,278,558...35,317,493
Ensembl chr14:35,278,633...35,317,493
JBrowse link
G PSMA7 proteasome 20S subunit alpha 7 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMA7 mRNA CTD PMID:31806706 NCBI chr20:62,136,733...62,143,394
Ensembl chr20:62,136,733...62,143,440
JBrowse link
G PSMB10 proteasome 20S subunit beta 10 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB10 mRNA CTD PMID:31806706 NCBI chr16:67,934,506...67,936,850
Ensembl chr16:67,934,506...67,936,864
JBrowse link
G PSMB2 proteasome 20S subunit beta 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB2 mRNA CTD PMID:31806706 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526
JBrowse link
G PSMB3 proteasome 20S subunit beta 3 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB3 mRNA CTD PMID:31806706 NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225
JBrowse link
G PSMB4 proteasome 20S subunit beta 4 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB4 mRNA CTD PMID:31806706 NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937
JBrowse link
G PSMB5 proteasome 20S subunit beta 5 increases expression
multiple interactions
decreases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB5 mRNA
[sodium arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of PSMB5 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased expression of PSMB5 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in decreased expression of PSMB5 protein]; sodium arsenite promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB5 mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB5 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB5 protein
CTD PMID:15525353 PMID:31806706 PMID:32301004 NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230
JBrowse link
G PSMB6 proteasome 20S subunit beta 6 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB6 mRNA CTD PMID:31806706 NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502
JBrowse link
G PSMB7 proteasome 20S subunit beta 7 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB7 mRNA CTD PMID:31806706 NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444
JBrowse link
G PSMB9 proteasome 20S subunit beta 9 decreases expression
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSMB9 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMB9 mRNA
CTD PMID:20061341 PMID:31806706 NCBI chr 6:32,854,192...32,859,851
Ensembl chr 6:32,844,136...32,859,851
JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC1 mRNA CTD PMID:31806706 NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429
JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC2 mRNA CTD PMID:31806706 NCBI chr 7:103,347,524...103,369,395
Ensembl chr 7:103,328,570...103,370,346
JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC3 mRNA CTD PMID:31806706 NCBI chr11:47,418,775...47,426,439
Ensembl chr11:47,418,769...47,426,473
JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC4 mRNA CTD PMID:31806706 NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764
JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction and affects the localization of [PSMC5 protein binds to GABBR2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC5 mRNA
CTD PMID:24482233 PMID:31806706 NCBI chr17:63,827,431...63,832,019
Ensembl chr17:63,827,152...63,832,026
JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMC6 mRNA CTD PMID:31806706 NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590
JBrowse link
G PSMD1 proteasome 26S subunit, non-ATPase 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD1 mRNA CTD PMID:31806706 NCBI chr 2:231,056,867...231,172,827
Ensembl chr 2:231,056,845...231,173,116
JBrowse link
G PSMD11 proteasome 26S subunit, non-ATPase 11 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD11 mRNA CTD PMID:31806706 NCBI chr17:32,444,510...32,483,319
Ensembl chr17:32,444,379...32,483,319
JBrowse link
G PSMD12 proteasome 26S subunit, non-ATPase 12 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD12 mRNA CTD PMID:31806706 NCBI chr17:67,337,916...67,366,577
Ensembl chr17:67,337,916...67,366,605
JBrowse link
G PSMD13 proteasome 26S subunit, non-ATPase 13 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD13 mRNA CTD PMID:31806706 NCBI chr11:236,976...252,984
Ensembl chr11:236,966...252,984
JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD14 mRNA CTD PMID:31806706 NCBI chr 2:161,308,425...161,411,717
Ensembl chr 2:161,308,425...161,411,717
JBrowse link
G PSMD2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD2 mRNA CTD PMID:31806706 NCBI chr 3:184,299,241...184,309,050
Ensembl chr 3:184,299,198...184,309,050
JBrowse link
G PSMD3 proteasome 26S subunit, non-ATPase 3 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD3 mRNA CTD PMID:31806706 NCBI chr17:39,980,807...39,997,959
Ensembl chr17:39,980,807...39,997,959
JBrowse link
G PSMD4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] CTD PMID:15362974 NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,709...151,267,479
JBrowse link
G PSMD6 proteasome 26S subunit, non-ATPase 6 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD6 mRNA CTD PMID:31806706 NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010
JBrowse link
G PSMD8 proteasome 26S subunit, non-ATPase 8 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSMD8 mRNA CTD PMID:31806706 NCBI chr19:38,374,571...38,383,824
Ensembl chr19:38,374,563...38,383,850
JBrowse link
G PSME1 proteasome activator subunit 1 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSME1 mRNA CTD PMID:31806706 NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967
JBrowse link
G PSME2 proteasome activator subunit 2 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PSME2 mRNA CTD PMID:31806706 NCBI chr14:24,143,365...24,146,610
Ensembl chr14:24,143,362...24,147,570
JBrowse link
G PSME4 proteasome activator subunit 4 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PSME4 mRNA CTD PMID:31806706 NCBI chr 2:53,864,069...53,970,993
Ensembl chr 2:53,864,069...53,970,993
JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions
increases ubiquitination
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc Sulfate results in decreased stability of PTEN protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of PTEN protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of PTEN protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTEN protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein]
CTD PMID:17684018 PMID:20100827 PMID:24449419 PMID:33256086 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGER1 prostaglandin E receptor 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein] CTD PMID:20335389 NCBI chr19:14,472,466...14,475,354
Ensembl chr19:14,472,466...14,475,354
JBrowse link
G PTGES3 prostaglandin E synthase 3 decreases degradation
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PTGES3 protein
4-tosylcyclonovobiocic acid promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PTGES3 protein]
CTD PMID:19118525 NCBI chr12:56,663,349...56,688,284
Ensembl chr12:56,663,341...56,688,408
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of PTGS2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTGS2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of PTGS2 protein
CTD PMID:11230753 PMID:12628480 PMID:12721113 PMID:17084486 PMID:18457675 More... NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTK2B protein tyrosine kinase 2 beta multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [PTK2B protein affects the ubiquitination of ESR1 protein] CTD PMID:29428397 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391
JBrowse link
G PTP4A3 protein tyrosine phosphatase 4A3 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PTP4A3 mRNA CTD PMID:25566086 NCBI chr 8:141,392,021...141,432,454
Ensembl chr 8:141,391,995...141,432,454
JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 multiple interactions EXP PTPN1 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of EIF2S1 protein] CTD PMID:28359145 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241
JBrowse link
G RAB33A RAB33A, member RAS oncogene family decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RAB33A mRNA CTD PMID:25566086 NCBI chr  X:130,110,623...130,184,870
Ensembl chr  X:130,171,962...130,184,870
JBrowse link
G RABL6 RAB, member RAS oncogene family like 6 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RABL6 mRNA CTD PMID:31806706 NCBI chr 9:136,807,948...136,841,187
Ensembl chr 9:136,807,943...136,841,187
JBrowse link
G RAD51 RAD51 recombinase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Mitomycin co-treated with Curcumin] results in decreased expression of RAD51 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Mitomycin results in increased expression of RAD51 protein]] CTD PMID:21810436 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340
JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein modified form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Arsenic Trioxide co-treated with PD 173074] results in decreased expression of RAF1 protein] CTD PMID:27794399 NCBI chr 3:12,583,601...12,664,117
Ensembl chr 3:12,582,101...12,664,201
JBrowse link
G RAMP1 receptor activity modifying protein 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RAMP1 mRNA CTD PMID:25566086 NCBI chr 2:237,858,880...237,912,106
Ensembl chr 2:237,858,893...237,912,106
JBrowse link
G RARA retinoic acid receptor alpha increases ubiquitination
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RARA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased degradation of RARA protein]
CTD PMID:20945414 PMID:24819975 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G RARRES2 retinoic acid receptor responder 2 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RARRES2 mRNA]
CTD PMID:25566086 NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662
JBrowse link
G RASSF5 Ras association domain family member 5 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RASSF5 protein results in decreased expression of CTNNB1 protein] CTD PMID:25217643 NCBI chr 1:206,507,531...206,589,448
Ensembl chr 1:206,507,531...206,589,448
JBrowse link
G RBL1 RB transcriptional corepressor like 1 increases expression
increases ubiquitination
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RBL1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [palbociclib results in decreased expression of RBL1 protein]; palbociclib promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RBL1 protein]
CTD PMID:20100483 NCBI chr20:36,996,349...37,095,997
Ensembl chr20:36,996,349...37,095,997
JBrowse link
G RBP3 retinol binding protein 3 decreases degradation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of RBP3 protein mutant form CTD PMID:23486466 NCBI chr10:47,348,363...47,357,881
Ensembl chr10:47,348,363...47,357,881
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein
[PSEN1 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the reaction [Cycloheximide results in decreased expression of RBPJ protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RBPJ protein]
CTD PMID:22302987 NCBI chr 4:26,105,449...26,435,131
Ensembl chr 4:26,163,455...26,435,131
JBrowse link
G RCN2 reticulocalbin 2 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RCN2 protein CTD PMID:21692457 NCBI chr15:76,931,749...76,954,393
Ensembl chr15:76,931,738...76,954,393
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit increases activity
decreases expression
increases ubiquitination
multiple interactions
affects localization
decreases activity
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein
MG132 pretreatment decreases expression of protein in liver of intestinal ischemia/reperfusion rats
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of RELA protein
Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [(+)-JQ1 compound affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cisplatin promotes the reaction [RELA protein binds to TP63 protein alternative form]] which results in increased degradation of TP63 protein alternative form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BRD4 mutant form affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [CIGB-552 peptide results in decreased expression of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Deoxycholic Acid results in increased localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trimethyltin chloride affects the localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of [NFKB1 protein binds to RELA protein]; SB 203580 inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of RELA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan affects the localization of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [halofuginone affects the localization of RELA protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased activity of RELA protein
CTD
RGD
PMID:11543732 PMID:12628480 PMID:12721113 PMID:14527959 PMID:14581482 More... RGD:401794136 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RGMA mRNA CTD PMID:25566086 NCBI chr15:93,035,271...93,089,211
Ensembl chr15:93,035,271...93,089,211
JBrowse link
G RHOB ras homolog family member B multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SMURF1 protein results in increased degradation of RHOB protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of RHOB protein] CTD PMID:30587574 PMID:31140275 NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
JBrowse link
G RHOC ras homolog family member C multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF168 protein results in decreased expression of RHOC protein] CTD PMID:34873829 NCBI chr 1:112,701,131...112,707,408
Ensembl chr 1:112,701,127...112,707,434
JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of and results in increased ubiquitination of RICTOR protein CTD PMID:25897075 NCBI chr 5:38,937,920...39,074,399
Ensembl chr 5:38,937,920...39,074,402
JBrowse link
G RNF144B ring finger protein 144B multiple interactions
decreases degradation
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile results in increased degradation of RNF144B protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride inhibits the reaction [Estrogens deficiency results in decreased degradation of RNF144B protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lithium Chloride results in increased degradation of RNF144B protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of RNF144B protein
CTD PMID:29724995 NCBI chr 6:18,387,350...18,468,870
Ensembl chr 6:18,387,350...18,468,870
JBrowse link
G RNF168 ring finger protein 168 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF168 protein results in decreased expression of RHOC protein] CTD PMID:34873829 NCBI chr 3:196,468,783...196,503,768
Ensembl chr 3:196,468,783...196,503,768
JBrowse link
G RNF187 ring finger protein 187 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ro 31-8220 results in decreased stability of RNF187 protein] CTD PMID:25851810 NCBI chr 1:228,487,382...228,496,188
Ensembl chr 1:228,487,382...228,499,899
JBrowse link
G RNF208 ring finger protein 208 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RNF208 mRNA CTD PMID:25566086 NCBI chr 9:137,220,259...137,223,408
Ensembl chr 9:137,220,247...137,222,240
JBrowse link
G RNF31 ring finger protein 31 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF31 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNFAIP3 protein]] CTD PMID:34416243 NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660
JBrowse link
G ROBO4 roundabout guidance receptor 4 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ROBO4 mRNA CTD PMID:25566086 NCBI chr11:124,883,691...124,897,865
Ensembl chr11:124,883,691...124,898,500
JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 multiple interactions
decreases phosphorylation
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]; Cycloheximide inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KB1 protein]]
Sirolimus promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased phosphorylation of RPS6KB1 protein]
CTD PMID:22689575 PMID:31645432 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RPTOR protein CTD PMID:25897075 NCBI chr17:80,544,838...80,966,368
Ensembl chr17:80,544,819...80,966,371
JBrowse link
G RRM2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of RRM2 mRNA CTD PMID:25566086 NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
JBrowse link
G RXRA retinoid X receptor alpha multiple interactions
increases expression
EXP [Alitretinoin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the localization of RXRA protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Alitretinoin results in increased degradation of RXRA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of and results in increased expression of RXRA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of RXRA protein
CTD PMID:12970875 PMID:15707588 PMID:17170071 PMID:22310326 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
JBrowse link
G SAE1 SUMO1 activating enzyme subunit 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SAE1 mRNA CTD PMID:20061341 NCBI chr19:47,130,835...47,210,636
Ensembl chr19:47,113,274...47,210,636
JBrowse link
G SCARB1 scavenger receptor class B member 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of SCARB1 protein] CTD PMID:22442701 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SELENBP1 selenium binding protein 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SELENBP1 mRNA CTD PMID:25566086 NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707
JBrowse link
G SESN2 sestrin 2 multiple interactions
increases ubiquitination
increases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cycloheximide results in decreased expression of SESN2 protein]; Lipopolysaccharides inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of SESN2 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SESN2 protein
CTD PMID:25637945 NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491
JBrowse link
G SET SET nuclear proto-oncogene decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SET protein CTD PMID:21692457 NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400
JBrowse link
G SF1 splicing factor 1 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SF1 mRNA CTD PMID:25566086 NCBI chr11:64,764,606...64,778,542
Ensembl chr11:64,764,606...64,778,786
JBrowse link
G SH3KBP1 SH3 domain containing kinase binding protein 1 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SH3KBP1 mRNA] CTD PMID:25566086 NCBI chr  X:19,533,977...19,887,600
Ensembl chr  X:19,533,977...19,887,600
JBrowse link
G SIAH2 siah E3 ubiquitin protein ligase 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SIAH2 mRNA CTD PMID:20061341 NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
JBrowse link
G SIRT1 sirtuin 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [ERCC6 gene mutant form results in decreased expression of SIRT1 protein] CTD PMID:25440059 NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
JBrowse link
G SIRT6 sirtuin 6 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SIRT6 protein results in decreased expression of EP300 protein] CTD PMID:27094368 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566
JBrowse link
G SKP1 S-phase kinase associated protein 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP1 mRNA CTD PMID:20061341 NCBI chr 5:134,148,935...134,176,950
Ensembl chr 5:134,148,935...134,176,964
JBrowse link
G SKP2 S-phase kinase associated protein 2 increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SKP2 mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SKP2 protein results in decreased expression of DUSP1 protein]
CTD PMID:20061341 PMID:34697729 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849
JBrowse link
G SLBP stem-loop histone mRNA binding protein multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of SLBP protein] CTD PMID:25266719 NCBI chr 4:1,692,731...1,712,319
Ensembl chr 4:1,692,731...1,712,344
JBrowse link
G SLC10A2 solute carrier family 10 member 2 increases expression
multiple interactions
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC10A2 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [resveratrol results in decreased expression of SLC10A2 protein]
CTD PMID:23872411 PMID:24498857 NCBI chr13:103,043,998...103,066,417
Ensembl chr13:103,043,998...103,066,417
JBrowse link
G SLC11A2 solute carrier family 11 member 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [PRKN protein results in decreased expression of SLC11A2 protein alternative form] CTD PMID:20089134 NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566
JBrowse link
G SLC29A1 solute carrier family 29 member 1 (Augustine blood group) increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC29A1 mRNA CTD PMID:31806706 NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142
JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases expression
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC2A1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of SLC2A1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of SLC2A1 protein]
CTD PMID:17442736 PMID:31850806 PMID:32461003 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893
JBrowse link
G SLC31A1 solute carrier family 31 member 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cisplatin results in increased degradation of SLC31A1 protein] CTD PMID:17108132 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492
JBrowse link
G SLC39A4 solute carrier family 39 member 4 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zinc results in increased degradation of SLC39A4 protein] CTD PMID:17202136 NCBI chr 8:144,412,414...144,416,844
Ensembl chr 8:144,409,742...144,416,844
JBrowse link
G SLC6A3 solute carrier family 6 member 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NDFIP1 protein results in decreased expression of SLC6A3 protein] CTD PMID:26300475 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
JBrowse link
G SLC6A9 solute carrier family 6 member 9 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC6A9 mRNA]
CTD PMID:25566086 NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
JBrowse link
G SLC7A11 solute carrier family 7 member 11 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A11 mRNA CTD PMID:25566086 NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
JBrowse link
G SLC7A3 solute carrier family 7 member 3 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SLC7A3 mRNA CTD PMID:25566086 NCBI chr  X:70,925,579...70,931,096
Ensembl chr  X:70,925,579...70,931,125
JBrowse link
G SLCO1B1 solute carrier organic anion transporter family member 1B1 multiple interactions
decreases degradation
EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SLCO1B1 protein mutant form] which binds to and results in increased uptake of estrone sulfate CTD PMID:31254566 NCBI chr12:21,131,194...21,239,796
Ensembl chr12:21,131,194...21,239,796
JBrowse link
G SLN sarcolipin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SLN mRNA CTD PMID:25566086 NCBI chr11:107,707,378...107,712,056
Ensembl chr11:107,707,378...107,719,693
JBrowse link
G SMTNL2 smoothelin like 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SMTNL2 mRNA CTD PMID:25566086 NCBI chr17:4,584,007...4,608,319
Ensembl chr17:4,583,999...4,608,319
JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SMURF1 protein results in increased degradation of RHOB protein] CTD PMID:30587574 NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108
JBrowse link
G SNCA synuclein alpha increases phosphorylation
multiple interactions
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of SNCA protein
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of and results in increased ubiquitination of NFE2L2 protein; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]
CTD PMID:33157086 PMID:38016618 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
JBrowse link
G SNRK SNF related kinase decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SNRK mRNA]
CTD PMID:25566086 NCBI chr 3:43,286,540...43,351,143
Ensembl chr 3:43,286,512...43,424,764
JBrowse link
G SOAT2 sterol O-acyltransferase 2 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SOAT2 mRNA CTD PMID:25566086 NCBI chr12:53,103,486...53,124,535
Ensembl chr12:53,103,486...53,124,535
JBrowse link
G SOCS3 suppressor of cytokine signaling 3 decreases degradation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SOCS3 protein CTD PMID:23782265 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
decreases expression
increases expression
EXP
ISO
[sodium arsenite co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of SOD1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[SOD1 protein results in increased susceptibility to Thimerosal] which results in decreased expression of KCNIP3 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC2 protein results in increased degradation of SOD1 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [BIRC3 protein results in increased degradation of SOD1 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of SOD1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [sodium arsenite results in increased expression of SOD1 mRNA]; sodium arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SOD1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SOD1 mRNA
CTD PMID:17309078 PMID:20061341 PMID:27773815 PMID:30503815 PMID:32301004 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions EXP [SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; CAT protein inhibits the reaction [[SOD2 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of HDAC2 protein] CTD PMID:12161520 PMID:24973648 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SORT1 sortilin 1 multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tetrabromocinnamic acid results in increased degradation of SORT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [wortmannin results in increased degradation of SORT1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SORT1 protein
CTD PMID:25805502 NCBI chr 1:109,309,575...109,397,918
Ensembl chr 1:109,309,568...109,397,918
JBrowse link
G SOX18 SRY-box transcription factor 18 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SOX18 mRNA CTD PMID:25566086 NCBI chr20:64,047,582...64,049,639
Ensembl chr20:64,047,582...64,049,639
JBrowse link
G SOX9 SRY-box transcription factor 9 multiple interactions EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form] which results in increased expression of SOX9 mRNA CTD PMID:27576690 NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416
JBrowse link
G SP1 Sp1 transcription factor multiple interactions ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [SP1 protein binds to ARNT promoter]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased activity of SP1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione results in decreased expression of SP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Daunorubicin results in decreased expression of SP1 protein]
CTD PMID:14529614 PMID:17409431 PMID:34963561 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
JBrowse link
G SP3 Sp3 transcription factor multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SP3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SP3 protein
CTD PMID:25068794 NCBI chr 2:173,900,775...173,965,702
Ensembl chr 2:173,880,850...173,965,373
JBrowse link
G SPON2 spondin 2 multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPON2 mRNA] CTD PMID:25566086 NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962
JBrowse link
G SPRR2G small proline rich protein 2G multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SPRR2G mRNA] CTD PMID:25566086 NCBI chr 1:153,149,582...153,203,278
Ensembl chr 1:153,149,582...153,150,890
JBrowse link
G SPSB4 splA/ryanodine receptor domain and SOCS box containing 4 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SPSB4 mRNA]
CTD PMID:25566086 NCBI chr 3:141,051,347...141,148,611
Ensembl chr 3:141,051,347...141,148,611
JBrowse link
G SQSTM1 sequestosome 1 multiple interactions
increases expression
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG13 protein results in decreased expression of SQSTM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [ATG7 protein results in decreased expression of SQSTM1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 protein
[methylmercuric chloride co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased expression of SQSTM1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [SQSTM1 protein affects the susceptibility to methylmercuric chloride]; methylmercuric chloride promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SQSTM1 mRNA]
CTD PMID:27629431 PMID:37258240 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[arsenic trioxide co-treated with PD 173074] results in decreased expression of SRC protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [SRC protein binds to NR1I3 protein] CTD PMID:24224465 PMID:27794399 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G SRL sarcalumenin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SRL mRNA CTD PMID:25566086 NCBI chr16:4,189,374...4,242,080
Ensembl chr16:4,189,374...4,242,080
JBrowse link
G SRSF2 serine and arginine rich splicing factor 2 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [KAT5 protein results in increased acetylation of and results in increased degradation of SRSF2 protein] CTD PMID:21157427 NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333
JBrowse link
G SRXN1 sulfiredoxin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRXN1 mRNA CTD PMID:25566086 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G SRY sex determining region Y decreases degradation
increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRY protein modified form
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of SRY protein mutant form] which results in increased expression of SOX9 mRNA; SRY protein mutant form promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SRY protein modified form]
CTD PMID:27576690 NCBI chr  Y:2,786,855...2,787,682
Ensembl chr  Y:2,786,855...2,787,682
JBrowse link
G SSPN sarcospan decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of SSPN mRNA]
CTD PMID:25566086 NCBI chr12:26,121,991...26,234,777
Ensembl chr12:26,121,991...26,299,290
JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of and results in increased phosphorylation of STAT1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tretinoin results in increased expression of STAT1 mRNA] CTD PMID:20945414 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G STAT6 signal transducer and activator of transcription 6 affects phosphorylation EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the phosphorylation of STAT6 protein CTD PMID:12459556 NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
JBrowse link
G STK11 serine/threonine kinase 11 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of MYC protein]] CTD PMID:24793789 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G STRIP2 striatin interacting protein 2 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of STRIP2 mRNA CTD PMID:25566086 NCBI chr 7:129,434,432...129,488,399
Ensembl chr 7:129,434,432...129,488,399
JBrowse link
G STS steroid sulfatase multiple interactions
decreases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IGF2 protein results in increased expression of STS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tretinoin results in increased activity of STS protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of STS mRNA
CTD PMID:16178010 PMID:24055520 NCBI chr  X:7,147,290...7,354,641
Ensembl chr  X:7,147,237...7,804,358
JBrowse link
G SUV39H1 SUV39H1 histone lysine methyltransferase multiple interactions EXP 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; [TNF protein co-treated with 6-formylindolo(3,2-b)carbazole co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with Sirolimus co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein] CTD PMID:31676321 NCBI chr  X:48,695,554...48,709,016
Ensembl chr  X:48,695,554...48,709,016
JBrowse link
G SWT1 SWT1 RNA endoribonuclease homolog multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of SWT1 mRNA CTD PMID:25566086 NCBI chr 1:185,157,060...185,291,781
Ensembl chr 1:185,157,080...185,291,781
JBrowse link
G SYBU syntabulin multiple interactions
increases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of SYBU mRNA] CTD PMID:25566086 NCBI chr 8:109,573,978...109,691,600
Ensembl chr 8:109,573,978...109,691,791
JBrowse link
G SYNPO synaptopodin multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of SYNPO mRNA CTD PMID:25566086 NCBI chr 5:150,586,010...150,659,207
Ensembl chr 5:150,601,080...150,659,207
JBrowse link
G SYP synaptophysin multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] CTD PMID:18487452 NCBI chr  X:49,187,815...49,200,193
Ensembl chr  X:49,187,815...49,200,218
JBrowse link
G TAF1 TATA-box binding protein associated factor 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione results in decreased expression of TAF1 protein] CTD PMID:17409431 NCBI chr  X:71,366,357...71,530,525
Ensembl chr  X:71,366,136...71,532,374
JBrowse link
G TAF1A TATA-box binding protein associated factor, RNA polymerase I subunit A increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TAF1A mRNA CTD PMID:25566086 NCBI chr 1:222,554,105...222,589,933
Ensembl chr 1:222,557,902...222,589,933
JBrowse link
G TARDBP TAR DNA binding protein affects localization
increases ubiquitination
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the localization of TARDBP protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TARDBP protein
CTD PMID:19765185 PMID:31780563 NCBI chr 1:11,012,654...11,030,528
Ensembl chr 1:11,012,344...11,030,528
JBrowse link
G TDRP testis development related protein increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TDRP mRNA CTD PMID:25566086 NCBI chr 8:489,946...545,780
Ensembl chr 8:489,803...545,781
JBrowse link
G TENM4 teneurin transmembrane protein 4 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TENM4 mRNA]
CTD PMID:25566086 NCBI chr11:78,652,829...79,441,030
Ensembl chr11:78,652,829...79,441,030
JBrowse link
G TERT telomerase reverse transcriptase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [APP protein modified form results in decreased expression of and results in decreased activity of TERT protein] CTD PMID:21520056 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068
JBrowse link
G TESC tescalcin decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TESC mRNA CTD PMID:25566086 NCBI chr12:117,038,923...117,099,416
Ensembl chr12:117,038,923...117,099,479
JBrowse link
G TFAM transcription factor A, mitochondrial multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [troglitazone results in decreased expression of TFAM mRNA] CTD PMID:20860658 NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220
JBrowse link
G TFRC transferrin receptor decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TFRC mRNA]
CTD PMID:25566086 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
JBrowse link
G TG thyroglobulin multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Amiodarone results in decreased expression of TG protein] CTD PMID:25295624 NCBI chr 8:132,866,958...133,134,899
Ensembl chr 8:132,866,958...133,134,903
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TGFB1 protein results in decreased expression of LPIN1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TH5487 inhibits the reaction [TGFB1 protein results in increased expression of OGG1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [TGFB1 protein results in increased expression of OGG1 protein] CTD PMID:27345520 PMID:35654123 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFBI transforming growth factor beta induced decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TGFBI mRNA CTD PMID:25566086 NCBI chr 5:136,028,988...136,063,818
Ensembl chr 5:136,028,988...136,063,818
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tolfenamic acid results in decreased expression of TGFBR1 protein] CTD PMID:31381904 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G THY1 Thy-1 cell surface antigen decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of THY1 mRNA]
CTD PMID:25566086 NCBI chr11:119,415,476...119,424,985
Ensembl chr11:119,415,476...119,424,985
JBrowse link
G TIPARP TCDD inducible poly(ADP-ribose) polymerase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] CTD PMID:12147270 NCBI chr 3:156,674,590...156,706,770
Ensembl chr 3:156,673,235...156,706,770
JBrowse link
G TK1 thymidine kinase 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TK1 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TK1 mRNA
CTD PMID:20061341 PMID:25566086 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233
JBrowse link
G TMEM176A transmembrane protein 176A multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176A mRNA CTD PMID:25566086 NCBI chr 7:150,800,769...150,805,118
Ensembl chr 7:150,800,403...150,805,118
JBrowse link
G TMEM176B transmembrane protein 176B multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TMEM176B mRNA CTD PMID:25566086 NCBI chr 7:150,791,301...150,801,360
Ensembl chr 7:150,791,285...150,801,360
JBrowse link
G TMEM204 transmembrane protein 204 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMEM204 mRNA]
CTD PMID:25566086 NCBI chr16:1,528,678...1,555,568
Ensembl chr16:1,528,688...1,555,580
JBrowse link
G TMOD1 tropomodulin 1 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMOD1 mRNA]
CTD PMID:25566086 NCBI chr 9:97,501,180...97,601,743
Ensembl chr 9:97,501,180...97,601,743
JBrowse link
G TMT1A thiol methyltransferase 1A decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TMT1A mRNA CTD PMID:31806706 NCBI chr12:50,925,015...50,932,508
Ensembl chr12:50,923,472...50,932,510
JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
EXP
ISO
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with TNF protein] results in increased phosphorylation of NFKBIA protein; [TNF protein co-treated with 6-formylindolo(3,2-b)carbazole co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; [TNF protein co-treated with Sirolimus co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein; AHR protein affects the reaction [[TNF protein co-treated with alpinetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with alpinetin] results in decreased expression of SUV39H1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in increased expression of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased activity of MMP9 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CX3CL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of PTGS2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of VEGFA protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]
MG132 pretreatment decreases expression of TNFa, IL6 protein in serum of intestinal ischemia/reperfusion rats
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNF mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Diclofenac promotes the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Zymosan results in increased expression of TNF mRNA]
CTD
RGD
PMID:11230753 PMID:11698246 PMID:12185005 PMID:12628480 PMID:12883408 More... RGD:401794136 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFAIP1 TNF alpha induced protein 1 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNFAIP1 protein results in increased degradation of CSNK2B protein] CTD PMID:37302538 NCBI chr17:28,335,761...28,347,009
Ensembl chr17:28,335,602...28,347,009
JBrowse link
G TNFAIP3 TNF alpha induced protein 3 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [RNF31 protein inhibits the reaction [Lipopolysaccharides results in increased expression of TNFAIP3 protein]] CTD PMID:34416243 NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
JBrowse link
G TNFAIP8L1 TNF alpha induced protein 8 like 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNFAIP8L1 mRNA CTD PMID:20061341 NCBI chr19:4,639,516...4,655,568
Ensembl chr19:4,639,516...4,655,568
JBrowse link
G TNFRSF10A TNF receptor superfamily member 10a increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TNFRSF10A protein CTD PMID:16287099 NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102
JBrowse link
G TNFRSF10B TNF receptor superfamily member 10b increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TNFRSF10B protein CTD PMID:16287099 PMID:17510429 NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031
JBrowse link
G TNNI1 troponin I1, slow skeletal type decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI1 mRNA CTD PMID:25566086 NCBI chr 1:201,403,784...201,421,730
Ensembl chr 1:201,403,784...201,429,866
JBrowse link
G TNNI2 troponin I2, fast skeletal type decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI2 mRNA]
CTD PMID:25566086 NCBI chr11:1,838,981...1,841,678
Ensembl chr11:1,838,981...1,841,680
JBrowse link
G TNNI3 troponin I3, cardiac type multiple interactions
decreases expression
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Doxorubicin results in decreased expression of TNNI3 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TNNI3 mRNA
CTD PMID:19801490 PMID:25566086 NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
JBrowse link
G TOP2A DNA topoisomerase II alpha multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] CTD PMID:17575151 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
JBrowse link
G TP53 tumor protein p53 multiple interactions
increases expression
increases ubiquitination
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Capsaicin results in increased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Chlorpyrifos results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in increased degradation of TP53 protein mutant form]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of and results in increased expression of TP53 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein modified form
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of TP53 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Acetaminophen results in increased degradation of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased phosphorylation of and results in increased expression of TP53 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TP53 protein
CTD PMID:10837373 PMID:16330492 PMID:18463101 PMID:18951928 PMID:19699254 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
G TP63 tumor protein p63 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Cisplatin promotes the reaction [RELA protein binds to TP63 protein alternative form]] which results in increased degradation of TP63 protein alternative form] CTD PMID:21088498 NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276
JBrowse link
G TRAF2 TNF receptor associated factor 2 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TRAF2 protein results in decreased expression of KLF2 protein] CTD PMID:35635602 NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607
JBrowse link
G TRIB2 tribbles pseudokinase 2 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of TRIB2 mRNA CTD PMID:25566086 NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734
JBrowse link
G TRIB3 tribbles pseudokinase 3 decreases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIB3 mRNA CTD PMID:31806706 NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
JBrowse link
G TRIL TLR4 interactor with leucine rich repeats decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIL mRNA]
CTD PMID:25566086 NCBI chr 7:28,953,358...28,958,330
Ensembl chr 7:28,953,358...28,958,330
JBrowse link
G TRIM72 tripartite motif containing 72 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TRIM72 mRNA CTD PMID:25566086 NCBI chr16:31,214,119...31,231,537
Ensembl chr16:31,214,119...31,231,537
JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]] CTD PMID:20671745 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342
JBrowse link
G TSC22D4 TSC22 domain family member 4 decreases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA
MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of TSC22D4 mRNA]
CTD PMID:25566086 NCBI chr 7:100,466,519...100,479,214
Ensembl chr 7:100,463,359...100,479,232
JBrowse link
G TXNL1 thioredoxin like 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in increased degradation of TXNL1 protein] CTD PMID:19349280 NCBI chr18:56,597,209...56,638,592
Ensembl chr18:56,597,209...56,651,600
JBrowse link
G TXNRD1 thioredoxin reductase 1 increases expression EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of TXNRD1 mRNA CTD PMID:18550526 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G TYMP thymidine phosphorylase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tanespimycin inhibits the reaction [salinomycin results in increased expression of TYMP protein]] CTD PMID:21444628 PMID:30796972 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
JBrowse link
G TYMS thymidylate synthetase multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Fluorouracil co-treated with Cisplatin] results in decreased stability of TYMS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [cinobufagin results in decreased expression of TYMS protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [trichostatin A results in decreased expression of TYMS protein] CTD PMID:17172411 PMID:21444628 PMID:35427566 NCBI chr18:657,653...673,578
Ensembl chr18:657,653...673,578
JBrowse link
G TYR tyrosinase multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Fenofibrate results in decreased expression of TYR protein] CTD PMID:23872139 NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759
JBrowse link
G UBB ubiquitin B multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[PARK protein co-treated with UBB protein] results in decreased expression of FIS1 protein] CTD PMID:20164189 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G UBC ubiquitin C multiple interactions
increases expression
EXP
ISO
HSF1 promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBC mRNA] CTD PMID:30186748 NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
JBrowse link
G UBE2C ubiquitin conjugating enzyme E2 C decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UBE2C mRNA CTD PMID:20061341 NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957
JBrowse link
G UBE2T ubiquitin conjugating enzyme E2 T decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UBE2T mRNA CTD PMID:20061341 NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984
JBrowse link
G UBQLN1 ubiquilin 1 increases stability EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of UBQLN1 protein mutant form CTD PMID:24747970 NCBI chr 9:83,659,968...83,707,958
Ensembl chr 9:83,659,968...83,707,958
JBrowse link
G UBR1 ubiquitin protein ligase E3 component n-recognin 1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UBR1 mRNA CTD PMID:20061341 NCBI chr15:42,942,897...43,106,038
Ensembl chr15:42,942,897...43,106,113
JBrowse link
G UBXN1 UBX domain protein 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [NGLY1 protein binds to UBXN1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein] CTD PMID:15362974 NCBI chr11:62,676,500...62,679,073
Ensembl chr11:62,676,498...62,679,117
JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UCHL1 mRNA CTD PMID:20061341 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
JBrowse link
G UFD1 ubiquitin recognition factor in ER associated degradation 1 increases expression
multiple interactions
ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of UFD1 mRNA
[MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in increased expression of UFD1 mRNA
CTD PMID:20061341 PMID:25566086 NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202
JBrowse link
G UHRF1 ubiquitin like with PHD and ring finger domains 1 decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UHRF1 mRNA CTD PMID:25566086 NCBI chr19:4,903,080...4,962,154
Ensembl chr19:4,903,080...4,962,154
JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Nitrogen deficiency results in decreased expression of ULK1 protein] CTD PMID:27629431 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150
JBrowse link
G UNC13C unc-13 homolog C multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of UNC13C mRNA] CTD PMID:25566086 NCBI chr15:53,837,602...54,633,440
Ensembl chr15:53,978,201...54,628,707
JBrowse link
G USP14 ubiquitin specific peptidase 14 increases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of USP14 mRNA CTD PMID:20061341 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629
JBrowse link
G USP15 ubiquitin specific peptidase 15 multiple interactions ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]] CTD PMID:35478295 NCBI chr12:62,260,404...62,416,389
Ensembl chr12:62,260,338...62,417,431
JBrowse link
G USP28 ubiquitin specific peptidase 28 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel sulfate results in decreased expression of USP28 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen deficiency results in decreased expression of USP28 protein] CTD PMID:20046830 NCBI chr11:113,797,875...113,875,572
Ensembl chr11:113,797,874...113,875,572
JBrowse link
G USP7 ubiquitin specific peptidase 7 multiple interactions EXP [USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; [USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein; Arsenic inhibits the reaction [[USP7 protein mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [[USP7 protein co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in increased ubiquitination of HMOX1 protein]; Arsenic promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Sirolimus inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [USP7 protein affects the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of MCL1 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Wortmannin inhibits the reaction [[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of USP7 protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HMOX1 protein binds to USP7 protein]; USP7 protein affects the reaction [Arsenic inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein]]; USP7 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of HMOX1 protein] CTD PMID:32802178 PMID:35821281 NCBI chr16:8,892,097...8,963,906
Ensembl chr16:8,892,097...8,975,328
JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions
increases expression
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VCAM1 mRNA
CTD PMID:11698246 PMID:18457675 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045
JBrowse link
G VCP valosin containing protein increases expression
multiple interactions
EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VCP protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VCP protein binds to UBXN1 protein binds to PSMD4 protein]
CTD PMID:15362974 NCBI chr 9:35,056,064...35,072,625
Ensembl chr 9:35,053,928...35,072,668
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases expression
ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [methylmercuric chloride results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Methylmercury Compounds results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of VEGFA protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [andrographolide results in decreased expression of VEGFA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased expression of VEGFA mRNA]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [TNF protein results in increased secretion of VEGFA protein]
CTD PMID:12590138 PMID:24613819 PMID:28651835 PMID:31850806 PMID:32461003 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VHL von Hippel-Lindau tumor suppressor multiple interactions EXP [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [VHL protein binds to HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [HIF1A protein binds to VHL protein]] CTD PMID:17973296 PMID:19263519 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,667
JBrowse link
G VIM vimentin multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AHR protein results in decreased expression of VIM protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [AHR protein binds to VIM protein] CTD PMID:27752740 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G VWF von Willebrand factor decreases expression ISO benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of VWF mRNA CTD PMID:25566086 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
JBrowse link
G WWTR1 WW domain containing transcription regulator 1 multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin results in decreased expression of WWTR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tcdA protein, Clostridium difficile results in decreased expression of WWTR1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [toxB protein, Clostridium difficile results in decreased expression of WWTR1 protein] CTD PMID:33251692 PMID:33539684 NCBI chr 3:149,517,235...149,724,788
Ensembl chr 3:149,517,235...149,736,714
JBrowse link
G XBP1 X-box binding protein 1 decreases response to substance
increases expression
multiple interactions
EXP XBP1 protein results in decreased susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of XBP1 protein alternative form
4-phenylbutyric acid inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of XBP1 protein alternative form]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; [XBP1 mutant form co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] promotes the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]
CTD PMID:19135031 PMID:25568320 PMID:27638906 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
JBrowse link
G XIAP X-linked inhibitor of apoptosis multiple interactions
increases ubiquitination
increases cleavage
EXP
ISO
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[pifithrin co-treated with Topotecan] results in increased degradation of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cannabidiol promotes the reaction [DIABLO protein binds to XIAP protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cannabidiol results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Cannabidiol results in increased ubiquitination of XIAP protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [trimethyltin chloride results in decreased expression of XIAP protein]; Cannabidiol promotes the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of XIAP protein]
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of XIAP protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Topotecan results in increased degradation of XIAP protein]
CTD PMID:16287099 PMID:19812371 PMID:21411500 PMID:22627131 PMID:23423712 More... NCBI chr  X:123,859,708...123,913,972
Ensembl chr  X:123,859,712...123,913,972
JBrowse link
G XPC XPC complex subunit, DNA damage recognition and repair factor multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sodium arsenite results in decreased expression of XPC protein] CTD PMID:28237621 NCBI chr 3:14,145,147...14,178,601
Ensembl chr 3:14,145,147...14,178,621
JBrowse link
G YAP1 Yes1 associated transcriptional regulator multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [tcdA protein, Clostridium difficile results in decreased expression of YAP1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [toxB protein, Clostridium difficile results in decreased expression of YAP1 protein] CTD PMID:33251692 NCBI chr11:102,110,447...102,233,424
Ensembl chr11:102,110,447...102,233,424
JBrowse link
G ZBTB8B zinc finger and BTB domain containing 8B multiple interactions
decreases expression
ISO MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ZBTB8B mRNA] CTD PMID:25566086 NCBI chr 1:32,465,072...32,496,686
Ensembl chr 1:32,465,072...32,496,686
JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A increases expression ISO
EXP
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ZFAND2A mRNA
benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of ZFAND2A protein
CTD PMID:24619424 PMID:25566086 PMID:31540997 NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,152,071...1,160,759
JBrowse link
G ZFP36 ZFP36 ring finger protein multiple interactions EXP benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [hydroquinone results in decreased expression of ZFP36 protein] CTD PMID:23288922 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407
JBrowse link
G ZFYVE21 zinc finger FYVE-type containing 21 multiple interactions ISO [MYBPC3 protein affects the susceptibility to benzyloxycarbonylleucyl-leucyl-leucine aldehyde] which results in decreased expression of ZFYVE21 mRNA CTD PMID:25566086 NCBI chr14:103,715,810...103,733,664
Ensembl chr14:103,715,730...103,733,668
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26050
    role 25966
      application 25188
        pharmaceutical 24562
          drug 24559
            proteasome inhibitor 1410
              N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal 688
Path 2
Term Annotations click to browse term
  CHEBI ontology 26050
    subatomic particle 26025
      composite particle 26025
        hadron 26025
          baryon 26025
            nucleon 26025
              atomic nucleus 26025
                atom 26025
                  main group element atom 25850
                    p-block element atom 25850
                      carbon group element atom 25447
                        carbon atom 25405
                          organic molecular entity 25405
                            heteroorganic entity 24781
                              organochalcogen compound 24394
                                organooxygen compound 24071
                                  carbon oxoacid 22773
                                    carboxylic acid 22753
                                      carboacyl group 20066
                                        univalent carboacyl group 20066
                                          carbamoyl group 19580
                                            carboxamide 19580
                                              peptide 11632
                                                oligopeptide 1346
                                                  tripeptide 978
                                                    N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal 688
paths to the root