GABBR2 (gamma-aminobutyric acid type B receptor subunit 2) - Rat Genome Database

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Gene: GABBR2 (gamma-aminobutyric acid type B receptor subunit 2) Homo sapiens
Analyze
Symbol: GABBR2
Name: gamma-aminobutyric acid type B receptor subunit 2
RGD ID: 731754
HGNC Page HGNC:4507
Description: Enables protein heterodimerization activity. Contributes to G protein-coupled GABA receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and gamma-aminobutyric acid signaling pathway. Located in plasma membrane. Part of G protein-coupled GABA receptor complex and G protein-coupled receptor heterodimeric complex. Implicated in alcohol use disorder; developmental and epileptic encephalopathy 59; and nicotine dependence.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: DEE59; EIEE59; FLJ36928; G protein-coupled receptor 51; G-protein coupled receptor 51; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABA-B-R2; GABA-BR2; GABABR2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gb2; GPR51; GPRC3B; HG20; HRIHFB2099; NDPLHS
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38998,288,109 - 98,708,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl998,288,109 - 98,708,935 (-)EnsemblGRCh38hg38GRCh38
GRCh379101,050,391 - 101,471,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369100,090,187 - 100,511,300 (-)NCBINCBI36Build 36hg18NCBI36
Build 34998,129,920 - 98,551,034NCBI
Celera971,564,671 - 71,985,374 (-)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef970,650,446 - 70,940,183 (-)NCBIHuRef
CHM1_19101,196,866 - 101,617,897 (-)NCBICHM1_1
T2T-CHM13v2.09110,460,053 - 110,880,595 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
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Original Reference(s)
GABBR2Humanalcohol dependence  ISOGabbr2 (Rattus norvegicus)9068941mRNA:decreased expression:hippocampus (rat)RGDPMID:22253714 and REF_RGD_ID:401900163
GABBR2Humanalcohol use disorder susceptibilityIAGP 401940105DNA:SNP:intron: (rs2900512) (human)RGD 
GABBR2Humannicotine dependence  ISOGabbr2 (Rattus norvegicus)408395148mRNA and protein:altered expression:brainRGD 
GABBR2Humannicotine dependence susceptibilityIAGP 401940104DNA:SNPs and haplotypes:multipleRGD 
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GABBR2Humanautism spectrum disorder  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:25741868
GABBR2Humancongenital disorder of glycosylation Ii  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital disorder of glycosylation type 1IClinVarPMID:20813212 and PMID:28492532
GABBR2Humancongenital disorder of glycosylation type II  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: CDG IiClinVarPMID:20813212 and PMID:28492532
GABBR2Humancongenital myasthenic syndrome 14  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Myasthenic syndrome more ...ClinVarPMID:20813212 and PMID:28492532
GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 59ClinVarPMID:25741868 more ...
GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 59ClinVarPMID:25741868 more ...
GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 59ClinVarPMID:25741868
GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 59ClinVarPMID:25262651 more ...
GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 59ClinVarPMID:25741868 and PMID:28492532
GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 59ClinVar 
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 more ...
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532 more ...
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:17576681 more ...
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:16199547 more ...
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2Humangeneralized epilepsy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:17576681 more ...
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Original Reference(s)
GABBR2Humanautistic disorder  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:19002745
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GABBR2Humandevelopmental and epileptic encephalopathy 59  IAGP 7240710 OMIM 
GABBR2HumanNeurodevelopmental Disorder with Poor Language and Loss of Hand Skills  IAGP 7240710 OMIM 
GABBR2Humannicotine dependence  IAGP 7240710 OMIM 

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Original Reference(s)
GABBR2Human1-(3-chlorophenyl)piperazine multiple interactionsEXP 64804641-(3-chlorophenyl)piperazine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]CTDPMID:21729720
GABBR2Human17beta-estradiol affects expressionEXP 6480464Estradiol affects the expression of GABBR2 mRNACTDPMID:14699072
GABBR2Human17beta-estradiol decreases expressionISOGabbr2 (Mus musculus)6480464Estradiol results in decreased expression of GABBR2 mRNACTDPMID:39298647
GABBR2Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of GABBR2 mRNACTDPMID:19619570 and PMID:21185374
GABBR2Human17beta-estradiol multiple interactionsEXP 6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GABBR2 mRNA more ...CTDPMID:19619570 more ...
GABBR2Human2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOGabbr2 (Rattus norvegicus)6480464[2 more ...CTDPMID:21277884
GABBR2Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GABBR2 mRNACTDPMID:19619570
GABBR2Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGabbr2 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in increased expression of GABBR2 mRNACTDPMID:33387578
GABBR2Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGabbr2 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of GABBR2 mRNACTDPMID:32109520
GABBR2Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGabbr2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of GABBR2 mRNACTDPMID:26290441
GABBR2Human2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of GABBR2 mRNACTDPMID:16704738 and PMID:19619570
GABBR2Human2,3,7,8-Tetrachlorodibenzofuran decreases expressionISOGabbr2 (Rattus norvegicus)64804642 more ...CTDPMID:32109520
GABBR2Human3,3-diphenyl-N-(1-phenylethyl)-1-propanamine multiple interactionsEXP 6480464Fendiline inhibits the reaction [2 more ...CTDPMID:15627515
GABBR2Human3,4-Methylenedioxyamphetamine multiple interactionsEXP 64804643 and 4-Methylenedioxyamphetamine affects the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]]CTDPMID:21729720
GABBR2Human3-chloropropane-1,2-diol increases expressionISOGabbr2 (Rattus norvegicus)6480464alpha-Chlorohydrin results in increased expression of GABBR2 mRNACTDPMID:28522335
GABBR2Human4,4'-sulfonyldiphenol decreases expressionISOGabbr2 (Mus musculus)6480464bisphenol S results in decreased expression of GABBR2 mRNACTDPMID:39298647
GABBR2Human6-propyl-2-thiouracil decreases expressionISOGabbr2 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of GABBR2 mRNACTDPMID:30047161
GABBR2Human8-Br-cAMP decreases expressionEXP 64804648-Bromo Cyclic Adenosine Monophosphate results in decreased expression of GABBR2 mRNACTDPMID:22079614
GABBR2Humanacetamide increases expressionISOGabbr2 (Rattus norvegicus)6480464acetamide results in increased expression of GABBR2 mRNACTDPMID:31881176
GABBR2Humanacrylamide increases expressionISOGabbr2 (Rattus norvegicus)6480464Acrylamide results in increased expression of GABBR2 mRNACTDPMID:28959563

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Biological Process
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Original Reference(s)
GABBR2Humanadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway involved_inIDA 150520179 PMID:987231ComplexPortalPMID:987231
GABBR2Humanchemical synaptic transmission involved_inTAS 150520179 PMID:9872316PINCPMID:9872316
GABBR2HumanG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-0297150520179 UniProtGO_REF:0000043
GABBR2HumanG protein-coupled receptor signaling pathway involved_inTAS 150520179 PMID:9872316PINCPMID:9872316
GABBR2HumanG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000337 more ...150520179 InterProGO_REF:0000002
GABBR2Humangamma-aminobutyric acid signaling pathway  ISOGabbr2 (Rattus norvegicus)9068941 RGDPMID:11389174 and REF_RGD_ID:632824
GABBR2Humangamma-aminobutyric acid signaling pathway involved_inIBAFB:FBgn0027575 more ...150520179 GO_CentralGO_REF:0000033
GABBR2Humangamma-aminobutyric acid signaling pathway involved_inIDA 150520179 PMID:987231 and PMID:9872316ComplexPortalPMID:987231 and PMID:9872316
GABBR2Humannegative regulation of adenylate cyclase activity involved_inTAS 150520179 PMID:10328880PINCPMID:10328880
GABBR2Humanneuron-glial cell signaling involved_inISSUniProtKB:O88871150520179 ARUK-UCLGO_REF:0000024
GABBR2Humansignal transduction involved_inIEAUniProtKB-KW:KW-0807150520179 UniProtGO_REF:0000043
GABBR2Humansynaptic transmission, GABAergic involved_inNAS 150520179 PMID:987231ComplexPortalPMID:987231
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Cellular Component
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GABBR2Humancytoplasm located_inIEAUniProtKB:Q80T41 and ensembl:ENSMUSP00000103378150520179 EnsemblGO_REF:0000107
GABBR2HumanG protein-coupled GABA receptor complex part_ofIPI 150520179 PMID:24305054ComplexPortalPMID:24305054
GABBR2HumanG protein-coupled receptor heterodimeric complex part_ofIPIUniProtKB:Q9UBS5150520179 PMID:9872316UniProtPMID:9872316
GABBR2HumanG protein-coupled receptor heterodimeric complex part_ofIBAFB:FBgn0027575 more ...150520179 GO_CentralGO_REF:0000033
GABBR2HumanGABA receptor complex part_ofIDA 150520179 PMID:15304491CAFAPMID:15304491
GABBR2HumanGABA-ergic synapse is_active_inISOGabbr2 (Rattus norvegicus)9068941PMID:14657159SynGOPMID:14657159 and REF_RGD_ID:13702400
GABBR2Humanglutamatergic synapse is_active_inISOGabbr2 (Rattus norvegicus)9068941PMID:14657159SynGOPMID:14657159 and REF_RGD_ID:13702400
GABBR2Humanmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
GABBR2Humanmembrane located_inIEAUniProtKB-SubCell:SL-0162150520179 UniProtGO_REF:0000044
GABBR2Humanmembrane located_inIEAInterPro:IPR000337 more ...150520179 InterProGO_REF:0000002
GABBR2Humanneuron projection located_inIEAUniProtKB:Q80T41 and ensembl:ENSMUSP00000103378150520179 EnsemblGO_REF:0000107
GABBR2Humanplasma membrane located_inIDA 150520179 PMID:15304491 and PMID:9872316CAFAPMID:15304491 and PMID:9872316
GABBR2Humanplasma membrane located_inIEAUniProtKB-KW:KW-1003150520179 UniProtGO_REF:0000043
GABBR2Humanplasma membrane located_inTAS 150520179 PMID:10328880ReactomePMID:10328880 more ...
GABBR2Humanplasma membrane located_inIEAUniProtKB-SubCell:SL-0039150520179 UniProtGO_REF:0000044
GABBR2Humanpostsynaptic membrane located_inIEAUniProtKB-KW:KW-0628150520179 UniProtGO_REF:0000043
GABBR2Humanpostsynaptic membrane is_active_inISOGabbr2 (Rattus norvegicus)9068941PMID:14657159SynGOPMID:14657159 and REF_RGD_ID:13702400
GABBR2Humanpostsynaptic membrane located_inIEAUniProtKB-SubCell:SL-0219150520179 UniProtGO_REF:0000044
GABBR2Humanpresynaptic membrane is_active_inISOGabbr2 (Rattus norvegicus)9068941PMID:14657159SynGOPMID:14657159 and REF_RGD_ID:13702400
GABBR2Humansynapse located_inIEAUniProtKB-KW:KW-0770150520179 UniProtGO_REF:0000043
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Molecular Function
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Original Reference(s)
GABBR2HumanAddictive alcohol use susceptibilityIAGP 401940105DNA:SNP:intron: (rs2900512) (human)RGD 
GABBR2HumanAddictive nicotine use susceptibilityIAGP 401940104DNA:SNPs and haplotypes:multipleRGD 
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Original Reference(s)
GABBR2HumanAbnormal autonomic nervous system physiology  IAGP 8699517 HPOMIM:617903
GABBR2HumanAbnormal corpus callosum morphology  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAbnormal involuntary eye movements  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAbnormal muscle tone  IAGP 8699517 HPOORPHA:3095
GABBR2HumanAbnormal myelination  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAbnormal pattern of respiration  IAGP 8699517 HPOORPHA:3095
GABBR2HumanAbnormality of coordination  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAbnormality of movement  IAGP 8699517 HPOORPHA:3095
GABBR2HumanAbnormality of vision  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAbsent speech  IAGP 8699517 HPOMIM:617903
GABBR2HumanAbsent speech  IAGP 8699517 HPOMIM:617904
GABBR2HumanAgitation  IAGP 8699517 HPOORPHA:3095
GABBR2HumanAgitation  IAGP 8699517 HPOMIM:617903
GABBR2HumanApnea  IAGP 8699517 HPOMIM:617903
GABBR2HumanApraxia  IAGP 8699517 HPOORPHA:3095
GABBR2HumanAtaxia  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAtaxia  IAGP 8699517 HPOMIM:617904
GABBR2HumanAttention deficit hyperactivity disorder  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAtypical behavior  IAGP 8699517 HPOORPHA:442835
GABBR2HumanAutism  IAGP 8699517 HPOORPHA:442835
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Original Reference(s)
GABBR2HumanAutistic behavior  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:25741868
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 and PMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:25741868 more ...
GABBR2HumanEpileptic encephalopathy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epileptic encephalopathyClinVarPMID:28492532
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Reference Title
Reference Citation
1. Alcohol use disorder and GABAB receptor gene polymorphisms in an Italian sample: haplotype frequencies, linkage disequilibrium and association studies. Caputo F, etal., Ann Hum Biol. 2017 Jun;44(4):384-388. doi: 10.1080/03014460.2017.1287307. Epub 2017 Feb 14.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations. Li MD, etal., PLoS One. 2009 Sep 18;4(9):e7055. doi: 10.1371/journal.pone.0007055.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Regulation by nicotine of Gpr51 and Ntrk2 expression in various rat brain regions. Sun D, etal., Neuropsychopharmacology. 2007 Jan;32(1):110-6. doi: 10.1038/sj.npp.1301134. Epub 2006 Jun 21.
PMID:987231   PMID:2834384   PMID:7494864   PMID:9872316   PMID:9872317   PMID:10075644   PMID:10087195   PMID:10328880   PMID:10727622   PMID:10773016   PMID:11087824   PMID:11850456  
PMID:11854302   PMID:12477932   PMID:14625043   PMID:14961561   PMID:14966130   PMID:14978362   PMID:15164053   PMID:15304491   PMID:15489334   PMID:15660124   PMID:15822905   PMID:15905570  
PMID:16081421   PMID:16169070   PMID:16724110   PMID:16829628   PMID:17145756   PMID:17185339   PMID:17591780   PMID:18482426   PMID:18577758   PMID:18978678   PMID:19002745   PMID:19086053  
PMID:19308021   PMID:19336370   PMID:19744961   PMID:20379614   PMID:20424473   PMID:20557420   PMID:20583170   PMID:20634891   PMID:20734064   PMID:21303731   PMID:21724853   PMID:21873635  
PMID:21971078   PMID:22169202   PMID:22613715   PMID:22660477   PMID:23726511   PMID:23864651   PMID:23996491   PMID:24305054   PMID:24482233   PMID:24658140   PMID:24682435   PMID:24778228  
PMID:24923912   PMID:25450229   PMID:26539091   PMID:26817839   PMID:27033668   PMID:28298427   PMID:28323850   PMID:28490462   PMID:28856709   PMID:28867141   PMID:30343129   PMID:30971491  
PMID:32555460   PMID:32580208   PMID:32581365   PMID:33058878   PMID:33961781   PMID:34845648   PMID:37207277   PMID:37450587   PMID:37762034  



GABBR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38998,288,109 - 98,708,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl998,288,109 - 98,708,935 (-)EnsemblGRCh38hg38GRCh38
GRCh379101,050,391 - 101,471,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369100,090,187 - 100,511,300 (-)NCBINCBI36Build 36hg18NCBI36
Build 34998,129,920 - 98,551,034NCBI
Celera971,564,671 - 71,985,374 (-)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef970,650,446 - 70,940,183 (-)NCBIHuRef
CHM1_19101,196,866 - 101,617,897 (-)NCBICHM1_1
T2T-CHM13v2.09110,460,053 - 110,880,595 (-)NCBIT2T-CHM13v2.0
Gabbr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39446,662,318 - 46,991,714 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl446,662,305 - 46,991,873 (-)EnsemblGRCm39 Ensembl
GRCm38446,662,318 - 46,991,714 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl446,662,305 - 46,991,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv37446,676,770 - 47,004,586 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36446,684,998 - 47,012,814 (-)NCBIMGSCv36mm8
Celera446,675,526 - 47,003,236 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map425.18NCBI
Gabbr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,743,073 - 66,083,695 (-)NCBIGRCr8
mRatBN7.2560,947,517 - 61,288,104 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,947,526 - 61,288,104 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,918,639 - 63,259,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,738,005 - 65,079,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,707,402 - 65,048,578 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0562,276,100 - 62,621,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl562,276,100 - 62,621,737 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,802,348 - 67,142,203 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,241,397 - 63,611,907 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1563,241,575 - 63,612,086 (-)NCBI
Celera559,508,888 - 59,731,378 (-)NCBICelera
Cytogenetic Map5q22NCBI
Gabbr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541926,872,728 - 27,239,464 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541926,872,734 - 27,241,917 (+)NCBIChiLan1.0ChiLan1.0
GABBR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21140,747,751 - 41,170,503 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1940,750,129 - 41,172,879 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0969,377,091 - 69,799,867 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1997,500,606 - 97,919,053 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl997,500,904 - 97,790,605 (-)Ensemblpanpan1.1panPan2
GABBR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11155,469,327 - 55,817,930 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1155,470,197 - 55,817,945 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1153,902,316 - 54,251,118 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01156,578,376 - 56,927,274 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1156,580,523 - 56,927,865 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11155,076,468 - 55,431,616 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01155,107,840 - 55,455,961 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,804,321 - 56,153,068 (-)NCBIUU_Cfam_GSD_1.0
Gabbr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947170,397,327 - 170,750,253 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,943,147 - 7,297,835 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365246,944,923 - 7,297,833 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABBR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,107,466 - 240,496,101 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11240,107,469 - 240,495,917 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21268,546,934 - 268,740,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABBR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11240,719,126 - 41,135,602 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1240,719,577 - 41,135,770 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603837,753,365 - 38,173,474 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabbr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248252,233,759 - 2,610,255 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248252,233,759 - 2,608,159 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in GABBR2
962 total Variants

1 to 10 of 1123 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
NM_005458.8(GABBR2):c.360A>G (p.Ala120=) single nucleotide variant Epileptic encephalopathy [RCV001517760]|not provided [RCV001618284] Chr9:98578034 [GRCh38]
Chr9:101340316 [GRCh37]
Chr9:9q22.33		 benign
NM_005458.8(GABBR2):c.2774_2776dup (p.Pro925dup) duplication Epileptic encephalopathy [RCV000544481] Chr9:98290633..98290634 [GRCh38]
Chr9:101052915..101052916 [GRCh37]
Chr9:9q22.33		 uncertain significance
NM_005458.8(GABBR2):c.1450A>G (p.Ile484Val) single nucleotide variant Epileptic encephalopathy [RCV000528913] Chr9:98388933 [GRCh38]
Chr9:101151215 [GRCh37]
Chr9:9q22.33		 uncertain significance
NM_005458.8(GABBR2):c.1805G>C (p.Gly602Ala) single nucleotide variant Epileptic encephalopathy [RCV000551924]|not provided [RCV004760564] Chr9:98362803 [GRCh38]
Chr9:101125085 [GRCh37]
Chr9:9q22.33		 uncertain significance
NM_005458.8(GABBR2):c.2229+8C>T single nucleotide variant Epileptic encephalopathy [RCV000530500] Chr9:98306113 [GRCh38]
Chr9:101068395 [GRCh37]
Chr9:9q22.33		 benign|uncertain significance
GABABR2, HAPLOTYPE, TATA (rs1435252, rs3780422, rs2779562, rs3750344) variation Tobacco addiction, susceptibility to [RCV000003496] Chr9:9q22.1 risk factor
GABABR2, HAPLOTYPE, CACA (rs1435252, rs3780422, rs2779562, rs3750344) variation Nicotine dependence, protection against [RCV000003497] Chr9:9q22.1 protective
NM_005458.8(GABBR2):c.2265G>A (p.Thr755=) single nucleotide variant Epileptic encephalopathy [RCV000545240]|not provided [RCV004707322] Chr9:98303388 [GRCh38]
Chr9:101065670 [GRCh37]
Chr9:9q22.33		 likely benign
NM_005458.8(GABBR2):c.2619A>G (p.Arg873=) single nucleotide variant Epileptic encephalopathy [RCV000544461]|not provided [RCV001672832] Chr9:98293826 [GRCh38]
Chr9:101056108 [GRCh37]
Chr9:9q22.33		 benign
NM_005458.8(GABBR2):c.483T>C (p.Pro161=) single nucleotide variant Epileptic encephalopathy [RCV000548303]|not provided [RCV001707727] Chr9:98542020 [GRCh38]
Chr9:101304302 [GRCh37]
Chr9:9q22.33		 benign
1 to 10 of 1123 rows

Predicted Target Of
Summary Value
Count of predictions:1365
Count of miRNA genes:810
Interacting mature miRNAs:943
Transcripts:ENST00000259455, ENST00000477471
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597212505GWAS1308579_Hschizophrenia QTL GWAS1308579 (human)0.0000002schizophrenia99830924098309241Human
597048542GWAS1144616_Hovarian carcinoma QTL GWAS1144616 (human)0.000007ovarian carcinoma99857956998579570Human
597326679GWAS1422753_Hcolor vision disorder QTL GWAS1422753 (human)0.000001color vision disorder99838168298381683Human
407024850GWAS673826_Hhomocysteine measurement QTL GWAS673826 (human)2e-08homocysteine measurement99836105498361055Human
597095173GWAS1191247_Hschizophrenia QTL GWAS1191247 (human)0.0000006schizophrenia99831434598314346Human
407050512GWAS699488_Htriacylglycerol 54:3 measurement QTL GWAS699488 (human)0.000006blood triglyceride amount (VT:0002644)99845173998451740Human
597021190GWAS1117264_Hsystolic blood pressure change measurement QTL GWAS1117264 (human)0.0000005systolic blood pressure change measurementchange in systolic blood pressure (CMO:0000746)99853587398535874Human
596970758GWAS1090277_Hdry eye syndrome QTL GWAS1090277 (human)0.000007dry eye syndrome99858690598586906Human
407050839GWAS699815_Htriacylglycerol 54:4 measurement QTL GWAS699815 (human)0.000002blood triglyceride amount (VT:0002644)99845173998451740Human
597162383GWAS1258457_Hlipid measurement QTL GWAS1258457 (human)0.00001lipid measurementblood lipid measurement (CMO:0000050)99838168298381683Human

1 to 10 of 25 rows
D9S763  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,410,114 - 101,410,466UniSTSGRCh37
Build 369100,449,935 - 100,450,287RGDNCBI36
Celera971,924,018 - 71,924,370RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef971,009,455 - 71,009,829UniSTS
Marshfield Genetic Map9105.02UniSTS
Marshfield Genetic Map9105.02RGD
SHGC-32035  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,050,423 - 101,050,548UniSTSGRCh37
Build 369100,090,244 - 100,090,369RGDNCBI36
Celera971,564,730 - 71,564,855RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,650,505 - 70,650,630UniSTS
Stanford-G3 RH Map93382.0UniSTS
Whitehead-RH Map9360.3UniSTS
NCBI RH Map9830.1UniSTS
GeneMap99-G3 RH Map93280.0UniSTS
SHGC-34267  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,064,799 - 101,064,948UniSTSGRCh37
Build 369100,104,620 - 100,104,769RGDNCBI36
Celera971,579,105 - 71,579,254RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,664,880 - 70,665,029UniSTS
TNG Radiation Hybrid Map937612.0UniSTS
Stanford-G3 RH Map93377.0UniSTS
GeneMap99-GB4 RH Map9318.07UniSTS
Whitehead-RH Map9360.3UniSTS
NCBI RH Map9829.2UniSTS
GeneMap99-G3 RH Map93275.0UniSTS
SHGC-79744  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,405,359 - 101,405,694UniSTSGRCh37
Build 369100,445,180 - 100,445,515RGDNCBI36
Celera971,919,263 - 71,919,598RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef971,004,700 - 71,005,035UniSTS
TNG Radiation Hybrid Map938064.0UniSTS
SHGC-145933  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,445,739 - 101,446,009UniSTSGRCh37
Build 369100,485,560 - 100,485,830RGDNCBI36
Celera971,959,635 - 71,959,905RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef971,045,090 - 71,045,360UniSTS
TNG Radiation Hybrid Map938098.0UniSTS
SHGC-149617  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,318,216 - 101,318,511UniSTSGRCh37
Build 369100,358,037 - 100,358,332RGDNCBI36
Celera971,832,493 - 71,832,788RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,917,938 - 70,918,233UniSTS
GPR51_2329  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,050,362 - 101,051,059UniSTSGRCh37
Build 369100,090,183 - 100,090,880RGDNCBI36
Celera971,564,669 - 71,565,366RGD
HuRef970,650,444 - 70,651,141UniSTS
GPR51  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,050,470 - 101,050,530UniSTSGRCh37
Build 369100,090,291 - 100,090,351RGDNCBI36
Celera971,564,777 - 71,564,837RGD
HuRef970,650,552 - 70,650,612UniSTS
G10723  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,370,959 - 101,371,159UniSTSGRCh37
GRCh37735,944,446 - 35,944,650UniSTSGRCh37
Build 36735,910,971 - 35,911,175RGDNCBI36
Celera735,928,171 - 35,928,375RGD
Celera971,884,881 - 71,885,081UniSTS
Cytogenetic Map7p14.2UniSTS
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef735,825,541 - 35,825,745UniSTS
HuRef970,970,309 - 70,970,509UniSTS
CRA_TCAGchr7v2735,982,477 - 35,982,681UniSTS
RH18549  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,064,863 - 101,065,046UniSTSGRCh37
Build 369100,104,684 - 100,104,867RGDNCBI36
Celera971,579,169 - 71,579,352RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,664,944 - 70,665,127UniSTS
GeneMap99-GB4 RH Map9319.07UniSTS
RH17868  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,064,904 - 101,065,034UniSTSGRCh37
Build 369100,104,725 - 100,104,855RGDNCBI36
Celera971,579,210 - 71,579,340RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,664,985 - 70,665,115UniSTS
GeneMap99-GB4 RH Map9318.01UniSTS
RH68438  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,175,834 - 101,175,982UniSTSGRCh37
Build 369100,215,655 - 100,215,803RGDNCBI36
Celera971,690,123 - 71,690,271RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,775,893 - 70,776,041UniSTS
GeneMap99-GB4 RH Map9318.12UniSTS
RH18328  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh379101,051,593 - 101,051,732UniSTSGRCh37
Build 369100,091,414 - 100,091,553RGDNCBI36
Celera971,565,900 - 71,566,039RGD
Cytogenetic Map9q22.1-q22.3UniSTS
HuRef970,651,675 - 70,651,814UniSTS
GeneMap99-GB4 RH Map9318.01UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
989 2254 2598 1915 4853 1542 2063 4 441 1090 287 2090 5613 5012 29 3684 655 1559 1537 163 1


1 to 30 of 30 rows
RefSeq Transcripts NG_016426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005252316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017015331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017015332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054364212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB015334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF056085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF069755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF074483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF095784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF099033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ012188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL353782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL356282 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL445495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL591502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX420187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX452140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS059179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB474482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ308173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 30 rows

Ensembl Acc Id: ENST00000259455   ⟹   ENSP00000259455
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,288,109 - 98,708,935 (-)Ensembl
Ensembl Acc Id: ENST00000477471
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,473,230 - 98,555,898 (-)Ensembl
Ensembl Acc Id: ENST00000634227
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,473,336 - 98,607,650 (-)Ensembl
Ensembl Acc Id: ENST00000634314
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,362,555 - 98,388,887 (-)Ensembl
Ensembl Acc Id: ENST00000634354
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,304,178 - 98,306,571 (-)Ensembl
Ensembl Acc Id: ENST00000634457   ⟹   ENSP00000489352
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,303,330 - 98,371,571 (-)Ensembl
Ensembl Acc Id: ENST00000634919
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,454,164 - 98,516,299 (-)Ensembl
Ensembl Acc Id: ENST00000635462
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,306,214 - 98,375,307 (-)Ensembl
Ensembl Acc Id: ENST00000636575
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,302,843 - 98,303,334 (-)Ensembl
Ensembl Acc Id: ENST00000637410
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,290,647 - 98,581,179 (-)Ensembl
Ensembl Acc Id: ENST00000637717   ⟹   ENSP00000490789
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,541,887 - 98,707,461 (-)Ensembl
Ensembl Acc Id: ENST00000638001
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl998,542,013 - 98,552,118 (-)Ensembl
RefSeq Acc Id: NM_005458   ⟹   NP_005449
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38998,288,109 - 98,708,935 (-)NCBI
GRCh379101,050,364 - 101,471,479 (-)ENTREZGENE
GRCh379101,050,364 - 101,471,479 (-)NCBI
Build 369100,090,187 - 100,511,300 (-)NCBI Archive
HuRef970,650,446 - 70,940,183 (-)NCBI
CHM1_19101,196,866 - 101,617,897 (-)NCBI
T2T-CHM13v2.09110,460,053 - 110,880,595 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005252316   ⟹   XP_005252373
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38998,288,109 - 98,538,668 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017015331   ⟹   XP_016870820
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38998,288,109 - 98,555,988 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017015332   ⟹   XP_016870821
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38998,288,109 - 98,487,336 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054364210   ⟹   XP_054220185
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.09110,460,053 - 110,727,907 (-)NCBI
RefSeq Acc Id: XM_054364211   ⟹   XP_054220186
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.09110,460,053 - 110,710,590 (-)NCBI
RefSeq Acc Id: XM_054364212   ⟹   XP_054220187
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.09110,460,053 - 110,659,238 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_005449   ⟸   NM_005458
- Peptide Label: precursor
- UniProtKB: Q9UNR1 (UniProtKB/Swiss-Prot),   Q9P1R2 (UniProtKB/Swiss-Prot),   Q8WX04 (UniProtKB/Swiss-Prot),   Q5VXZ2 (UniProtKB/Swiss-Prot),   O75975 (UniProtKB/Swiss-Prot),   O75974 (UniProtKB/Swiss-Prot),   Q9UNS9 (UniProtKB/Swiss-Prot),   O75899 (UniProtKB/Swiss-Prot),   H9NIL8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005252373   ⟸   XM_005252316
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016870820   ⟸   XM_017015331
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016870821   ⟸   XM_017015332
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSP00000489352   ⟸   ENST00000634457
G-protein coupled receptors family 3 profile   Receptor ligand binding region

Name Modeler Protein Id AA Range Protein Structure
AF-O75899-F1-model_v2 AlphaFold O75899 1-941 view protein structure

RGD ID:7215645
Promoter ID:EPDNEW_H13566
Type:initiation region
Name:GABBR2_2
Description:gamma-aminobutyric acid type B receptor subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H13567  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38998,708,935 - 98,708,995EPDNEW
RGD ID:7215641
Promoter ID:EPDNEW_H13567
Type:initiation region
Name:GABBR2_1
Description:gamma-aminobutyric acid type B receptor subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H13566  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38998,709,216 - 98,709,276EPDNEW


1 to 40 of 50 rows
Database
Acc Id
Source(s)
COSMIC GABBR2 COSMIC
Ensembl Genes ENSG00000136928 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000259455 ENTREZGENE
  ENST00000259455.4 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.2300 UniProtKB/Swiss-Prot
GTEx ENSG00000136928 GTEx
HGNC ID HGNC:4507 ENTREZGENE
Human Proteome Map GABBR2 Human Proteome Map
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot
  GBR2_CC UniProtKB/Swiss-Prot
  GPCR3_GABA-B UniProtKB/Swiss-Prot
  GPCR_3 UniProtKB/Swiss-Prot
  GPCR_3_C UniProtKB/Swiss-Prot
  GPCR_3_CS UniProtKB/Swiss-Prot
  GPCR_3_GABA_rcpt_B2 UniProtKB/Swiss-Prot
  Peripla_BP_I UniProtKB/Swiss-Prot
KEGG Report hsa:9568 UniProtKB/Swiss-Prot
NCBI Gene 9568 ENTREZGENE
OMIM 607340 OMIM
PANTHER GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 UniProtKB/Swiss-Prot
  PTHR10519 UniProtKB/Swiss-Prot
Pfam 7tm_3 UniProtKB/Swiss-Prot
  ANF_receptor UniProtKB/Swiss-Prot
  GBR2_CC UniProtKB/Swiss-Prot
PharmGKB PA28896 PharmGKB
PRINTS GABAB2RECPTR UniProtKB/Swiss-Prot
  GABABRECEPTR UniProtKB/Swiss-Prot
  GPCRMGR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F3_3 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F3_4 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53822 UniProtKB/Swiss-Prot
UniProt A0A0U1RR59_HUMAN UniProtKB/TrEMBL
  A0A1B0GW60_HUMAN UniProtKB/TrEMBL
  GABR2_HUMAN UniProtKB/Swiss-Prot
  H9NIL8 ENTREZGENE, UniProtKB/TrEMBL
  O75899 ENTREZGENE
  O75974 ENTREZGENE
  O75975 ENTREZGENE
  Q5VXZ2 ENTREZGENE
  Q8WX04 ENTREZGENE
1 to 40 of 50 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 GABBR2  gamma-aminobutyric acid type B receptor subunit 2    gamma-aminobutyric acid (GABA) B receptor, 2  Symbol and/or name change 5135510 APPROVED