Gabbr2 (gamma-aminobutyric acid type B receptor subunit 2) - Rat Genome Database

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Gene: Gabbr2 (gamma-aminobutyric acid type B receptor subunit 2) Chinchilla lanigera
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Symbol: Gabbr2
Name: gamma-aminobutyric acid type B receptor subunit 2
RGD ID: 8838365
Description: ENCODES a protein that exhibits G protein-coupled GABA receptor activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); gamma-aminobutyric acid signaling pathway (ortholog); neuron-glial cell signaling (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); alcohol use disorder (ortholog); autism spectrum disorder (ortholog); FOUND IN cytoplasm (ortholog); G protein-coupled GABA receptor complex (ortholog); G protein-coupled receptor heterodimeric complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gamma-aminobutyric acid (GABA) B receptor, 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541926,872,728 - 27,239,464 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541926,872,734 - 27,241,917 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gabbr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541926,872,728 - 27,239,464 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541926,872,734 - 27,241,917 (+)NCBIChiLan1.0ChiLan1.0
GABBR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38998,288,109 - 98,708,935 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl998,288,109 - 98,708,935 (-)EnsemblGRCh38hg38GRCh38
GRCh379101,050,391 - 101,471,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369100,090,187 - 100,511,300 (-)NCBINCBI36Build 36hg18NCBI36
Build 34998,129,920 - 98,551,034NCBI
Celera971,564,671 - 71,985,374 (-)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef970,650,446 - 70,940,183 (-)NCBIHuRef
CHM1_19101,196,866 - 101,617,897 (-)NCBICHM1_1
T2T-CHM13v2.09110,460,053 - 110,880,595 (-)NCBIT2T-CHM13v2.0
Gabbr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39446,662,318 - 46,991,714 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl446,662,305 - 46,991,873 (-)EnsemblGRCm39 Ensembl
GRCm38446,662,318 - 46,991,714 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl446,662,305 - 46,991,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv37446,676,770 - 47,004,586 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36446,684,998 - 47,012,814 (-)NCBIMGSCv36mm8
Celera446,675,526 - 47,003,236 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map425.18NCBI
Gabbr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,743,073 - 66,083,695 (-)NCBIGRCr8
mRatBN7.2560,947,517 - 61,288,104 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,947,526 - 61,288,104 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,918,639 - 63,259,788 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,738,005 - 65,079,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,707,402 - 65,048,578 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0562,276,100 - 62,621,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl562,276,100 - 62,621,737 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,802,348 - 67,142,203 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,241,397 - 63,611,907 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1563,241,575 - 63,612,086 (-)NCBI
Celera559,508,888 - 59,731,378 (-)NCBICelera
Cytogenetic Map5q22NCBI
GABBR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21140,747,751 - 41,170,503 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1940,750,129 - 41,172,879 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0969,377,091 - 69,799,867 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1997,500,606 - 97,919,053 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl997,500,904 - 97,790,605 (-)Ensemblpanpan1.1panPan2
GABBR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11155,469,327 - 55,817,930 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1155,470,197 - 55,817,945 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1153,902,316 - 54,251,118 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01156,578,376 - 56,927,274 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1156,580,523 - 56,927,865 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11155,076,468 - 55,431,616 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01155,107,840 - 55,455,961 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,804,321 - 56,153,068 (-)NCBIUU_Cfam_GSD_1.0
Gabbr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947170,397,327 - 170,750,253 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,943,147 - 7,297,835 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365246,944,923 - 7,297,833 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABBR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,107,466 - 240,496,101 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11240,107,469 - 240,495,917 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21268,546,934 - 268,740,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABBR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11240,719,126 - 41,135,602 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1240,719,577 - 41,135,770 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603837,753,365 - 38,173,474 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabbr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248252,233,759 - 2,610,255 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248252,233,759 - 2,608,159 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000015582   ⟹   ENSCLAP00000015421
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541926,872,728 - 27,239,464 (+)Ensembl
RefSeq Acc Id: XM_005382826   ⟹   XP_005382883
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541926,872,734 - 27,241,917 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005382883 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015421
  ENSCLAP00000015421.1
RefSeq Acc Id: XP_005382883   ⟸   XM_005382826
- UniProtKB: A0A8C2YQA9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000015421   ⟸   ENSCLAT00000015582

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010613 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015582 ENTREZGENE
  ENSCLAT00000015582.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GBR2_CC UniProtKB/TrEMBL
  GPCR3_GABA-B UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_CS UniProtKB/TrEMBL
  GPCR_3_GABA_rcpt_B2 UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene Gabbr2 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 UniProtKB/TrEMBL
  PTHR10519 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  GBR2_CC UniProtKB/TrEMBL
PRINTS GABAB2RECPTR UniProtKB/TrEMBL
  GABABRECEPTR UniProtKB/TrEMBL
  GPCRMGR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A8C2YQA9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Gabbr2  gamma-aminobutyric acid type B receptor subunit 2    gamma-aminobutyric acid (GABA) B receptor, 2  Symbol and/or name change 5135510 APPROVED