VCP (valosin containing protein) - Rat Genome Database

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Gene: VCP (valosin containing protein) Homo sapiens
Analyze
Symbol: VCP
Name: valosin containing protein
RGD ID: 731621
HGNC Page HGNC:12666
Description: Enables several functions, including ATP hydrolysis activity; enzyme binding activity; and modification-dependent protein binding activity. Involved in several processes, including DNA repair; proteolysis involved in protein catabolic process; and regulation of signal transduction. Located in several cellular components, including cytoplasmic stress granule; lipid droplet; and site of double-strand break. Part of VCP-NSFL1C complex; endoplasmic reticulum membrane; and proteasome complex. Is active in endoplasmic reticulum membrane. Implicated in several diseases, including Charcot-Marie-Tooth disease type 2Y; Paget's disease of bone; frontotemporal dementia and/or amyotrophic lateral sclerosis 6; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 1; and inclusion body myositis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 15S Mg(2+)-ATPase p97 subunit; ALS14; CDC48; CMT2Y; epididymis luminal protein 220; epididymis secretory protein Li 70; FTDALS6; HEL-220; HEL-S-70; IBMPFD; IBMPFD1; MGC131997; MGC148092; MGC8560; p97; TER ATPase; TERA; transitional endoplasmic reticulum ATPase; valosin-containing protein; yeast Cdc48p homolog
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,056,064 - 35,072,625 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,053,928 - 35,072,668 (-)EnsemblGRCh38hg38GRCh38
GRCh37935,056,061 - 35,072,622 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,046,560 - 35,062,564 (-)NCBINCBI36Build 36hg18NCBI36
Build 34935,046,560 - 35,062,564NCBI
Celera934,988,041 - 35,004,706 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,011,651 - 35,028,327 (-)NCBIHuRef
CHM1_1935,055,907 - 35,072,605 (-)NCBICHM1_1
T2T-CHM13v2.0935,075,243 - 35,091,804 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (EXP)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,5-hexanedione  (ISO)
2,6-dinitrotoluene  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (EXP)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bisphenol F  (EXP)
bortezomib  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP)
calcidiol  (ISO)
ceruletide  (ISO)
chenodeoxycholic acid  (EXP)
chloropicrin  (EXP)
chloroquine  (EXP,ISO)
chlorpyrifos  (ISO)
chromium trinitrate  (ISO)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
deoxycholic acid  (EXP)
diarsenic trioxide  (EXP)
dichlorine  (ISO)
diethylstilbestrol  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
fenvalerate  (ISO)
finasteride  (ISO)
flutamide  (ISO)
folic acid  (ISO)
FR900359  (EXP)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
hyaluronic acid  (ISO)
hydrazine  (ISO)
hydrogen peroxide  (ISO)
isoflavones  (ISO)
ivermectin  (EXP)
L-serine  (EXP)
lactacystin  (EXP)
lead(II) chloride  (EXP)
leflunomide  (EXP)
lipopolysaccharide  (EXP)
lovastatin  (ISO)
lycopene  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
naphthalene  (ISO)
nefazodone  (ISO)
ochratoxin A  (ISO)
okadaic acid  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
piroxicam  (EXP)
potassium chromate  (EXP,ISO)
prostaglandin A1  (ISO)
quartz  (EXP)
quercetin  (EXP)
resveratrol  (EXP)
rotenone  (EXP,ISO)
silicon dioxide  (EXP)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
sulforaphane  (EXP)
sulindac  (ISO)
sunitinib  (EXP)
tamoxifen  (ISO)
taurine  (EXP)
temozolomide  (EXP)
testosterone enanthate  (EXP)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (EXP)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP)
vinclozolin  (ISO)
vorinostat  (EXP)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO,ISS)
aggresome assembly  (IEA,ISO)
ATP metabolic process  (IEA)
autophagosome maturation  (IBA,IMP)
autophagy  (IEA,IMP)
cellular response to arsenite ion  (IMP)
cellular response to heat  (IMP)
cellular response to misfolded protein  (IMP)
cellular response to stress  (IEA)
cytoplasm protein quality control  (IDA)
DNA damage response  (IDA)
DNA repair  (IEA,NAS)
double-strand break repair  (IDA)
endoplasmic reticulum stress-induced pre-emptive quality control  (IMP)
endoplasmic reticulum to Golgi vesicle-mediated transport  (IEA,ISO)
endoplasmic reticulum unfolded protein response  (TAS)
endosome to lysosome transport via multivesicular body sorting pathway  (IMP)
ERAD pathway  (IDA,IEA,IMP,ISO,TAS)
establishment of protein localization  (TAS)
flavin adenine dinucleotide catabolic process  (IMP)
interstrand cross-link repair  (ISS)
macroautophagy  (IMP)
mitotic spindle disassembly  (IBA)
NADH metabolic process  (IMP)
negative regulation of hippo signaling  (IGI)
negative regulation of protein localization to chromatin  (IDA)
negative regulation of smoothened signaling pathway  (IMP)
positive regulation of ATP biosynthetic process  (IMP)
positive regulation of canonical Wnt signaling pathway  (IDA)
positive regulation of Lys63-specific deubiquitinase activity  (IDA)
positive regulation of mitochondrial membrane potential  (IEA,IMP)
positive regulation of non-canonical NF-kappaB signal transduction  (IDA)
positive regulation of oxidative phosphorylation  (IMP)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (IDA)
positive regulation of protein catabolic process  (IDA)
positive regulation of protein K63-linked deubiquitination  (IDA)
positive regulation of protein-containing complex assembly  (IDA)
positive regulation of ubiquitin-dependent protein catabolic process  (IEA,ISO)
proteasomal protein catabolic process  (IMP)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IDA,IEA,IMP,NAS)
protein ubiquitination  (IDA,NAS)
protein-DNA covalent cross-linking repair  (IDA)
regulation of aerobic respiration  (IMP)
regulation of apoptotic process  (TAS)
regulation of protein localization to chromatin  (IDA)
regulation of synapse organization  (IEA)
retrograde protein transport, ER to cytosol  (IBA,IDA,IEA,IMP,ISO)
stress granule disassembly  (IDA,IMP)
translesion synthesis  (IMP)
ubiquitin-dependent protein catabolic process  (IEA,ISO,NAS)
viral genome replication  (IMP)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal brain FDG positron emission tomography  (IAGP)
Abnormal calvaria morphology  (IAGP)
Abnormal cerebral white matter morphology  (IAGP)
Abnormal long bone morphology  (IAGP)
Abnormal lower motor neuron morphology  (IAGP)
Abnormal mitochondrial morphology  (IAGP)
Abnormal motor neuron morphology  (IAGP)
Abnormal pelvic girdle bone morphology  (IAGP)
Abnormal skeletal morphology  (IAGP)
Abnormal upper motor neuron morphology  (IAGP)
Abnormality of extrapyramidal motor function  (IAGP)
Abnormality of the musculature of the lower limbs  (IAGP)
Abnormality of the vertebral column  (IAGP)
Abnormality on pulmonary function testing  (IAGP)
Abolished vibration sense  (IAGP)
Absent Achilles reflex  (IAGP)
Abulia  (IAGP)
Aggressive behavior  (IAGP)
Alexia  (IAGP)
Alzheimer disease  (IAGP)
Amyotrophic lateral sclerosis  (IAGP)
Ankle clonus  (IAGP)
Anxiety  (IAGP)
Apathy  (IAGP)
Aphasia  (IAGP)
Apraxia  (IAGP)
Arthralgia  (IAGP)
Astrocytosis  (IAGP)
Atypical behavior  (IAGP)
Autosomal dominant inheritance  (IAGP)
Babinski sign  (IAGP)
Back pain  (IAGP)
Bilateral sensorineural hearing impairment  (IAGP)
Bilateral tonic-clonic seizure  (IAGP)
Bone pain  (IAGP)
Bowel incontinence  (IAGP)
Brain atrophy  (IAGP)
Brain neoplasm  (IAGP)
Brisk reflexes  (IAGP)
Broad-based gait  (IAGP)
Bulbar palsy  (IAGP)
Cachexia  (IAGP)
Calvarial hyperostosis  (IAGP)
Cardiomyopathy  (IAGP)
Cataract  (IAGP)
Childhood onset  (IAGP)
Cognitive impairment  (IAGP)
Collectionism  (IAGP)
Congestive heart failure  (IAGP)
Cranial nerve compression  (IAGP)
Decreased motor nerve conduction velocity  (IAGP)
Decreased nerve conduction velocity  (IAGP)
Deficit in grammar  (IAGP)
Degeneration of the lateral corticospinal tracts  (IAGP)
Dementia  (IAGP)
Depression  (IAGP)
Difficulty climbing stairs  (IAGP)
Difficulty running  (IAGP)
Disinhibition  (IAGP)
Distal amyotrophy  (IAGP)
Distal lower limb muscle weakness  (IAGP)
Distal muscle weakness  (IAGP)
Distal sensory impairment  (IAGP)
Distal upper limb muscle weakness  (IAGP)
Drooling  (IAGP)
Dysarthria  (IAGP)
Dyscalculia  (IAGP)
Dysgraphia  (IAGP)
Dyslexia  (IAGP)
Dysphagia  (IAGP)
Dysphonia  (IAGP)
Dyspnea  (IAGP)
Dystonia  (IAGP)
Echolalia  (IAGP)
EEG with continuous slow activity  (IAGP)
Elevated alkaline phosphatase of bone origin  (IAGP)
Elevated circulating alkaline phosphatase concentration  (IAGP)
Elevated circulating creatine kinase concentration  (IAGP)
EMG: chronic denervation signs  (IAGP)
EMG: myopathic abnormalities  (IAGP)
EMG: neuropathic changes  (IAGP)
Emotional dearth  (IAGP)
Emotional lability  (IAGP)
Expressive aphasia  (IAGP)
Facial diplegia  (IAGP)
Facial palsy  (IAGP)
Fasciculations  (IAGP)
Fatigable weakness of bulbar muscles  (IAGP)
Fatigable weakness of respiratory muscles  (IAGP)
Fatigable weakness of swallowing muscles  (IAGP)
Fatigue  (IAGP)
Fatty replacement of skeletal muscle  (IAGP)
Foot dorsiflexor weakness  (IAGP)
Frequent falls  (IAGP)
Frontal cortical atrophy  (IAGP)
Frontotemporal cerebral atrophy  (IAGP)
Frontotemporal dementia  (IAGP)
Gait disturbance  (IAGP)
Gait imbalance  (IAGP)
Generalized amyotrophy  (IAGP)
Generalized muscle weakness  (IAGP)
Gliosis  (IAGP)
Global brain atrophy  (IAGP)
Global developmental delay  (IAGP)
Hallucinations  (IAGP)
Hammertoe  (IAGP)
Hand muscle atrophy  (IAGP)
Hepatic steatosis  (IAGP)
Hip pain  (IAGP)
Hoffmann sign  (IAGP)
Hyperlordosis  (IAGP)
Hyperorality  (IAGP)
Hyperreflexia  (IAGP)
Hyporeflexia  (IAGP)
Impaired distal tactile sensation  (IAGP)
Impaired distal vibration sensation  (IAGP)
Impaired pain sensation  (IAGP)
Impaired tactile sensation  (IAGP)
Impaired vibration sensation in the lower limbs  (IAGP)
Inappropriate behavior  (IAGP)
Increased spinal bone density  (IAGP)
Increased susceptibility to fractures  (IAGP)
Increased variability in muscle fiber diameter  (IAGP)
Intellectual disability  (IAGP)
Intrinsic hand muscle atrophy  (IAGP)
Irritability  (IAGP)
Jaw hyperreflexia  (IAGP)
Lack of insight  (IAGP)
Language impairment  (IAGP)
Laryngospasm  (IAGP)
Late young adult onset  (IAGP)
Lewy bodies  (IAGP)
Limb fasciculations  (IAGP)
Limb muscle weakness  (IAGP)
Limited knee flexion  (IAGP)
Loss of ambulation  (IAGP)
Loss of speech  (IAGP)
Lower limb hyperreflexia  (IAGP)
Lower limb muscle weakness  (IAGP)
Lower limb spasticity  (IAGP)
Lumbar hyperlordosis  (IAGP)
Memory impairment  (IAGP)
Mental deterioration  (IAGP)
Middle age onset  (IAGP)
Mildly elevated creatine kinase  (IAGP)
Motor axonal neuropathy  (IAGP)
Motor neuron atrophy  (IAGP)
Motor stereotypy  (IAGP)
Muscle spasm  (IAGP)
Muscle weakness  (IAGP)
Mutism  (IAGP)
Myalgia  (IAGP)
Myopathy  (IAGP)
Necrotizing myopathy  (IAGP)
Neurodegeneration  (IAGP)
Neurofibrillary tangles  (IAGP)
Neuronal loss in the cerebral cortex  (IAGP)
Orthopnea  (IAGP)
Osteolysis  (IAGP)
Paget disease of bone  (IAGP)
Pain  (IAGP)
Paralysis  (IAGP)
Paraparesis  (IAGP)
Paresthesia  (IAGP)
Parkinsonism  (IAGP)
Pathologic fracture  (IAGP)
Pelvic girdle amyotrophy  (IAGP)
Pelvic girdle muscle atrophy  (IAGP)
Pelvic girdle muscle weakness  (IAGP)
Peripheral axonal neuropathy  (IAGP)
Perseverative thought  (IAGP)
Personality changes  (IAGP)
Pes cavus  (IAGP)
Poor fine motor coordination  (IAGP)
Poor speech  (IAGP)
Progressive  (IAGP)
Progressive cerebellar ataxia  (IAGP)
Progressive distal muscular atrophy  (IAGP)
Progressive neurologic deterioration  (IAGP)
Progressive proximal muscle weakness  (IAGP)
Proximal muscle weakness  (IAGP)
Proximal muscle weakness in lower limbs  (IAGP)
Proximal muscle weakness in upper limbs  (IAGP)
Psychosis  (IAGP)
Ptosis  (IAGP)
Quadriceps muscle weakness  (IAGP)
Recurrent fractures  (IAGP)
Reduced tendon reflexes  (IAGP)
Reduced vital capacity  (IAGP)
Respiratory failure  (IAGP)
Restlessness  (IAGP)
Restrictive behavior  (IAGP)
Rimmed vacuoles  (IAGP)
Scapular winging  (IAGP)
Senile plaques  (IAGP)
Sensorimotor neuropathy  (IAGP)
Sensory axonal neuropathy  (IAGP)
Short stature  (IAGP)
Shoulder girdle muscle atrophy  (IAGP)
Shoulder girdle muscle weakness  (IAGP)
Skeletal muscle atrophy  (IAGP)
Sleep abnormality  (IAGP)
Spastic gait  (IAGP)
Spastic paraparesis  (IAGP)
Spastic paraplegia  (IAGP)
Spasticity  (IAGP)
Spoken word recognition deficit  (IAGP)
Steppage gait  (IAGP)
Stroke  (IAGP)
Supranuclear gaze palsy  (IAGP)
Temporal cortical atrophy  (IAGP)
Tetraparesis  (IAGP)
Thickened nuchal skin fold  (IAGP)
Tip-toe gait  (IAGP)
Tongue atrophy  (IAGP)
Tongue fasciculations  (IAGP)
Tremor  (IAGP)
Type 1 muscle fiber predominance  (IAGP)
Ubiquitin-positive cerebral inclusion bodies  (IAGP)
Upper limb muscle weakness  (IAGP)
Upper motor neuron dysfunction  (IAGP)
Urinary bladder sphincter dysfunction  (IAGP)
Urinary incontinence  (IAGP)
Waddling gait  (IAGP)
Weakness due to upper motor neuron dysfunction  (IAGP)
Weakness of muscles of respiration  (IAGP)
Weakness of the intrinsic hand muscles  (IAGP)
Weight loss  (IAGP)
Xerostomia  (IAGP)
Young adult onset  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Oestrogen receptor-beta CA repeat polymorphism is associated with incidence of colorectal cancer among females. Honma N, etal., Histopathology. 2011 Aug;59(2):216-24. doi: 10.1111/j.1365-2559.2011.03914.x.
3. The ESR2 AluI 1730G>A (rs4986938) gene polymorphism is associated with fibrinogen plasma levels in postmenopausal women. Marini H, etal., Gene. 2012 Oct 25;508(2):206-10. doi: 10.1016/j.gene.2012.08.004. Epub 2012 Aug 11.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Double-strand break repair: 53BP1 comes into focus. Panier S and Boulton SJ, Nat Rev Mol Cell Biol. 2014 Jan;15(1):7-18. doi: 10.1038/nrm3719. Epub 2013 Dec 11.
6. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
11. Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Watts GD, etal., Nat Genet. 2004 Apr;36(4):377-81. Epub 2004 Mar 21.
Additional References at PubMed
PMID:1602151   PMID:7553851   PMID:8413590   PMID:8595912   PMID:8889548   PMID:9286697   PMID:9321476   PMID:9452483   PMID:9506515   PMID:10350210   PMID:10364224   PMID:10855792  
PMID:10930447   PMID:10931946   PMID:11087817   PMID:11252708   PMID:11483959   PMID:11689694   PMID:11913976   PMID:11927012   PMID:12351637   PMID:12473691   PMID:12477932   PMID:12504076  
PMID:12504083   PMID:12509440   PMID:12529442   PMID:12560433   PMID:12663780   PMID:12665801   PMID:12807884   PMID:12810701   PMID:12937274   PMID:12944474   PMID:14532270   PMID:14743216  
PMID:14749733   PMID:14760088   PMID:15037256   PMID:15161933   PMID:15189447   PMID:15215856   PMID:15331598   PMID:15362974   PMID:15371428   PMID:15452376   PMID:15456787   PMID:15588985  
PMID:15592455   PMID:15723043   PMID:15732117   PMID:15743842   PMID:15752563   PMID:15883021   PMID:15932873   PMID:15952740   PMID:16009940   PMID:16027165   PMID:16051665   PMID:16130169  
PMID:16140914   PMID:16159877   PMID:16168377   PMID:16186509   PMID:16186510   PMID:16196087   PMID:16212419   PMID:16234241   PMID:16236267   PMID:16247064   PMID:16275660   PMID:16289116  
PMID:16306228   PMID:16344560   PMID:16386250   PMID:16407162   PMID:16449189   PMID:16461343   PMID:16513638   PMID:16525503   PMID:16551632   PMID:16601695   PMID:16621797   PMID:16723740  
PMID:16783167   PMID:16807242   PMID:16822850   PMID:16901789   PMID:16914519   PMID:16954204   PMID:16966435   PMID:16968747   PMID:16987818   PMID:17110338   PMID:17141156   PMID:17200190  
PMID:17220478   PMID:17272822   PMID:17311810   PMID:17314412   PMID:17346713   PMID:17353931   PMID:17368566   PMID:17457594   PMID:17493577   PMID:17525332   PMID:17550899   PMID:17618707  
PMID:17620599   PMID:17622780   PMID:17626287   PMID:17681147   PMID:17683050   PMID:17763460   PMID:17872946   PMID:17889967   PMID:17907600   PMID:17935506   PMID:18022694   PMID:18029348  
PMID:18044963   PMID:18048502   PMID:18160415   PMID:18166610   PMID:18199748   PMID:18216283   PMID:18261755   PMID:18279508   PMID:18341608   PMID:18400946   PMID:18544453   PMID:18550891  
PMID:18586029   PMID:18654987   PMID:18656546   PMID:18675248   PMID:18706391   PMID:18711132   PMID:18775313   PMID:18811591   PMID:18835813   PMID:19056867   PMID:19164805   PMID:19174149  
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PMID:21645854   PMID:21653829   PMID:21684747   PMID:21733848   PMID:21741246   PMID:21781992   PMID:21811234   PMID:21822278   PMID:21832065   PMID:21857022   PMID:21873635   PMID:21896481  
PMID:21900206   PMID:21909096   PMID:21909394   PMID:21914798   PMID:21918864   PMID:21920633   PMID:21949850   PMID:21959292   PMID:21981919   PMID:21983102   PMID:21984748   PMID:21988832  
PMID:22038470   PMID:22040362   PMID:22078486   PMID:22090097   PMID:22102026   PMID:22105171   PMID:22119785   PMID:22120668   PMID:22137929   PMID:22190034   PMID:22196955   PMID:22207755  
PMID:22210628   PMID:22216170   PMID:22270372   PMID:22298039   PMID:22321369   PMID:22328510   PMID:22337587   PMID:22349865   PMID:22350894   PMID:22355145   PMID:22360420   PMID:22379090  
PMID:22466964   PMID:22536440   PMID:22572540   PMID:22579784   PMID:22586326   PMID:22590560   PMID:22607976   PMID:22623428   PMID:22681889   PMID:22686199   PMID:22699758   PMID:22789697  
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PMID:25147182   PMID:25192599   PMID:25231079   PMID:25416956   PMID:25437307   PMID:25447673   PMID:25457024   PMID:25463965   PMID:25492614   PMID:25526666   PMID:25566966   PMID:25593058  
PMID:25618255   PMID:25660456   PMID:25694454   PMID:25756610   PMID:25775548   PMID:25796446   PMID:25814554   PMID:25865307   PMID:25874486   PMID:25878907   PMID:25921289   PMID:25959826  
PMID:25963833   PMID:25970786   PMID:26107514   PMID:26112410   PMID:26134898   PMID:26168958   PMID:26186194   PMID:26217791   PMID:26265139   PMID:26311884   PMID:26320413   PMID:26337389  
PMID:26344197   PMID:26389662   PMID:26424800   PMID:26463207   PMID:26463447   PMID:26471130   PMID:26471729   PMID:26475856   PMID:26496610   PMID:26504085   PMID:26511028   PMID:26511642  
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PMID:30886048   PMID:30890647   PMID:31059266   PMID:31073040   PMID:31091164   PMID:31091453   PMID:31177093   PMID:31180492   PMID:31239290   PMID:31267705   PMID:31300519   PMID:31316150  
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PMID:34642328   PMID:34644576   PMID:34645483   PMID:34696522   PMID:34709727   PMID:34728620   PMID:34739333   PMID:34761751   PMID:34780058   PMID:34824462   PMID:34831176   PMID:34901782  
PMID:34964862   PMID:35007762   PMID:35013556   PMID:35032548   PMID:35122331   PMID:35256949   PMID:35271311   PMID:35349166   PMID:35356984   PMID:35385564   PMID:35389758   PMID:35405035  
PMID:35446349   PMID:35469923   PMID:35509820   PMID:35516420   PMID:35530310   PMID:35546148   PMID:35552390   PMID:35562734   PMID:35563018   PMID:35563538   PMID:35681168   PMID:35687106  
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PMID:36261009   PMID:36288698   PMID:36300783   PMID:36318477   PMID:36339263   PMID:36424410   PMID:36490346   PMID:36517590   PMID:36543142   PMID:36574265   PMID:36584595   PMID:36597993  
PMID:36610398   PMID:36656859   PMID:36692217   PMID:36695651   PMID:36746962   PMID:36762613   PMID:36779763   PMID:36857408   PMID:36880596   PMID:36896912   PMID:36964131   PMID:36980948  
PMID:37002192   PMID:37031316   PMID:37071682   PMID:37105989   PMID:37108544   PMID:37120454   PMID:37167062   PMID:37223481   PMID:37264685   PMID:37277335   PMID:37287368   PMID:37374283  
PMID:37545006   PMID:37689310   PMID:37713320   PMID:37756124   PMID:37788309   PMID:37816088   PMID:37827155   PMID:37866880   PMID:37883978   PMID:37931956   PMID:38081446   PMID:38113892  
PMID:38335961   PMID:38467645   PMID:38537699   PMID:38697112   PMID:38710747   PMID:38758288   PMID:38762759   PMID:38803224  


Genomics

Comparative Map Data
VCP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,056,064 - 35,072,625 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,053,928 - 35,072,668 (-)EnsemblGRCh38hg38GRCh38
GRCh37935,056,061 - 35,072,622 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,046,560 - 35,062,564 (-)NCBINCBI36Build 36hg18NCBI36
Build 34935,046,560 - 35,062,564NCBI
Celera934,988,041 - 35,004,706 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,011,651 - 35,028,327 (-)NCBIHuRef
CHM1_1935,055,907 - 35,072,605 (-)NCBICHM1_1
T2T-CHM13v2.0935,075,243 - 35,091,804 (-)NCBIT2T-CHM13v2.0
Vcp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39442,979,964 - 43,000,507 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl442,979,963 - 43,000,507 (-)EnsemblGRCm39 Ensembl
GRCm38442,979,964 - 43,000,507 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl442,979,963 - 43,000,507 (-)EnsemblGRCm38mm10GRCm38
MGSCv37442,992,836 - 43,013,379 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,001,064 - 43,021,534 (-)NCBIMGSCv36mm8
Celera443,010,123 - 43,030,659 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map422.95NCBI
Vcp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,005,984 - 62,025,387 (-)NCBIGRCr8
mRatBN7.2557,210,167 - 57,229,571 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,210,168 - 57,229,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,183,339 - 59,202,747 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,002,153 - 61,021,561 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0560,987,322 - 61,006,704 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0558,426,548 - 58,445,953 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,426,549 - 58,445,953 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0562,951,999 - 62,971,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,472,100 - 59,491,508 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1559,472,279 - 59,491,687 (-)NCBI
Celera555,799,589 - 55,818,873 (-)NCBICelera
Cytogenetic Map5q22NCBI
Vcp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,107,164 - 1,124,076 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554721,111,649 - 1,124,076 (+)NCBIChiLan1.0ChiLan1.0
VCP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21189,517,045 - 89,533,247 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1989,522,985 - 89,539,187 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0934,907,147 - 34,923,227 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1935,712,937 - 35,729,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,712,937 - 35,729,588 (-)Ensemblpanpan1.1panPan2
VCP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,636,986 - 51,651,749 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1151,637,411 - 51,651,714 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,205,792 - 50,220,556 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01152,702,444 - 52,717,215 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1152,702,830 - 52,724,878 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,246,536 - 51,261,297 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,231,677 - 51,246,443 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01151,933,494 - 51,948,301 (-)NCBIUU_Cfam_GSD_1.0
Vcp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,538,385 - 166,554,770 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365243,085,500 - 3,102,466 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365243,085,959 - 3,102,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VCP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1235,851,206 - 235,869,634 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11235,854,532 - 235,869,712 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,379,929 - 263,394,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
VCP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,545,139 - 45,560,702 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1245,545,507 - 45,563,380 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603842,661,397 - 42,677,470 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vcp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624915253,240 - 270,501 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624915253,240 - 270,440 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in VCP
563 total Variants