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Gene: GLS (glutaminase) Homo sapiens
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Symbol: GLS
Name: glutaminase
Description: Exhibits glutaminase activity. Involved in glutamate homeostasis; glutamine family amino acid metabolic process; and protein homotetramerization. Localizes to the mitochondrion. Implicated in early infantile epileptic encephalopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AAD20; CASGID; DKFZp686D14231; DKFZp686O15119; EIEE71; FLJ10358; FLJ41499; GAC; GAM; GDPAG; GLS1; glutaminase C; glutaminase kidney isoform, mitochondrial; glutaminase, phosphate-activated; K-glutaminase; KGA; KIAA0838; L-glutamine amidohydrolase
Orthologs:
Mus musculus (house mouse) : Gls (glutaminase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gls (glutaminase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gls (glutaminase)
Pan paniscus (bonobo/pygmy chimpanzee) : GLS (glutaminase)
Canis lupus familiaris (dog) : GLS (glutaminase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gls (glutaminase)
Sus scrofa (pig) : GLS (glutaminase)
Chlorocebus sabaeus (African green monkey) : GLS (glutaminase)
Heterocephalus glaber (naked mole-rat) : Gls (glutaminase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2190,880,821 - 190,965,552 (+)Ensembl
GRCh38 Ensembl2190,880,827 - 190,965,552 (+)Ensembl
GRCh382190,880,821 - 190,965,552 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372191,745,547 - 191,830,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362191,453,792 - 191,538,021 (+)NCBINCBI36hg18NCBI36
Build 342191,571,102 - 191,655,771NCBI
Celera2185,340,136 - 185,424,375 (+)NCBI
Cytogenetic Map2q32.2NCBI
HuRef2183,605,181 - 183,689,941 (+)NCBIHuRef
CHM1_12191,751,387 - 191,836,127 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GLS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736636
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.