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Gene: PDPN (podoplanin) Homo sapiens
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Symbol: PDPN
Name: podoplanin
Description: Exhibits chaperone binding activity; chemokine binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of extracellular matrix disassembly; positive regulation of platelet aggregation; and wound healing, spreading of cells. Localizes to several cellular components, including cell projection membrane; leading edge of lamellipodium; and tetraspanin-enriched microdomain. Biomarker of carcinoma (multiple); germ cell cancer (multiple); glioblastoma multiforme; and in situ carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGGRUS; glycoprotein 36; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); OTS8; PA2.26; PA2.26 antigen; T1-alpha; T1A; T1A-2; T1A2; TI1A
Orthologs:
Mus musculus (house mouse) : Pdpn (podoplanin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdpn (podoplanin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdpn (podoplanin)
Pan paniscus (bonobo/pygmy chimpanzee) : PDPN (podoplanin)
Canis lupus familiaris (dog) : PDPN (podoplanin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdpn (podoplanin)
Sus scrofa (pig) : PDPN (podoplanin)
Chlorocebus sabaeus (African green monkey) : PDPN (podoplanin)
Heterocephalus glaber (naked mole-rat) : Pdpn (podoplanin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl113,583,465 - 13,617,957 (+)EnsemblGRCh38hg38GRCh38
GRCh38113,583,757 - 13,617,957 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37113,910,252 - 13,944,452 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36113,782,839 - 13,817,039 (+)NCBINCBI36hg18NCBI36
Celera112,392,151 - 12,426,304 (+)NCBI
Cytogenetic Map1p36.21NCBI
HuRef112,427,703 - 12,461,787 (+)NCBIHuRef
CHM1_1113,708,939 - 13,743,119 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PDPN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1606573
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.