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Gene: ANXA2 (annexin A2) Homo sapiens
Symbol: ANXA2
Name: annexin A2
Description: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: annexin II; annexin-2; ANX2; ANX2L4; CAL1H; calpactin I heavy chain; calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; HEL-S-270; LIP2; lipocortin II; LPC2; LPC2D; P36; PAP-IV; placental anticoagulant protein IV; protein I
Mus musculus (house mouse) : Anxa2 (annexin A2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Anxa2 (annexin A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Anxa2 (annexin A2)
Pan paniscus (bonobo/pygmy chimpanzee) : ANXA2 (annexin A2)
Canis lupus familiaris (dog) : ANXA2 (annexin A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Anxa2 (annexin A2)
Sus scrofa (pig) : ANXA2 (annexin A2)
more info ...
Related Pseudogenes: ANXA2P1   ANXA2P2   ANXA2P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381560,347,151 - 60,398,025 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371560,639,350 - 60,690,185 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361558,426,642 - 58,477,477 (-)NCBINCBI36hg18NCBI36
Build 341558,426,642 - 58,477,477NCBI
Celera1537,527,343 - 37,578,364 (-)NCBI
Cytogenetic Map15q22.2NCBI
HuRef1537,461,790 - 37,512,581 (-)NCBIHuRef
CHM1_11560,757,784 - 60,809,419 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ANXA2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736099
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.