Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | decreases expression | EXP | | 6480464 | epigallocatechin gallate results in decreased expression of TXNL1 mRNA | CTD | PMID:16084531 | (1->4)-beta-D-glucan | multiple interactions | ISO | Txnl1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TXNL1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Txnl1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TXNL1 mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | 1-Naphthylisothiocyanate results in increased expression of TXNL1 mRNA | CTD | PMID:20551477 | 17beta-estradiol | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of TXNL1 protein | CTD | PMID:32145629 | 1H-pyrazole | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | pyrazole results in increased expression of TXNL1 mRNA | CTD | PMID:17945193 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TXNL1 mRNA | CTD | PMID:19465110 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Txnl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TXNL1 mRNA | CTD | PMID:21570461 | 2,4,6-tribromophenol | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:19954255 | 2,6-dinitrotoluene | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of TXNL1 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of TXNL1 mRNA | CTD | PMID:30851411 | 3-chloropropane-1,2-diol | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin analog results in decreased expression of TXNL1 protein and alpha-Chlorohydrin results in decreased expression of TXNL1 protein | CTD | PMID:26597043 | 3-chloropropane-1,2-diol | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of TXNL1 protein | CTD | PMID:34915118 | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of TXNL1 mRNA | CTD | PMID:19162173 | 4-hydroxyphenyl retinamide | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Fenretinide results in increased expression of TXNL1 mRNA | CTD | PMID:28973697 | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Propylthiouracil affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of TXNL1 mRNA | CTD | PMID:30047161 | aflatoxin B1 | increases methylation | EXP | | 6480464 | Aflatoxin B1 results in increased methylation of TXNL1 gene | CTD | PMID:28458013 | aflatoxin B1 | decreases methylation | EXP | | 6480464 | Aflatoxin B1 results in decreased methylation of TXNL1 gene | CTD | PMID:27153756 | aflatoxin M1 | decreases expression | EXP | | 6480464 | Aflatoxin M1 results in decreased expression of TXNL1 mRNA | CTD | PMID:30928695 | amiodarone | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Amiodarone affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | amitrole | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Amitrole results in increased expression of TXNL1 mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of TXNL1 mRNA | CTD | PMID:16483693 | aristolochic acid A | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of TXNL1 protein | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TXNL1 mRNA | CTD | PMID:23650126 | arsenite(3-) | multiple interactions | EXP | | 6480464 | arsenite inhibits the reaction [TXNL1 protein binds to PSMA1 protein] and benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in increased degradation of TXNL1 protein] | CTD | PMID:19349280 | arsenite(3-) | decreases expression | EXP | | 6480464 | arsenite results in decreased expression of TXNL1 protein | CTD | PMID:19349280 | benzbromarone | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Benzbromarone affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TXNL1 mRNA | CTD | PMID:21569818 | beta-naphthoflavone | increases expression | EXP | | 6480464 | beta-Naphthoflavone results in increased expression of TXNL1 mRNA | CTD | PMID:19737606 | bis(2-ethylhexyl) phthalate | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of TXNL1 mRNA | CTD | PMID:19850644 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Txnl1 (Mus musculus) | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of TXNL1 mRNA] | CTD | PMID:19850644 | bisphenol A | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of TXNL1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of TXNL1 mRNA | CTD | PMID:34947998 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TXNL1 mRNA | CTD | PMID:30903817 | Bisphenol B | increases expression | EXP | | 6480464 | bisphenol B results in increased expression of TXNL1 protein | CTD | PMID:34186270 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of TXNL1 protein | CTD | PMID:34186270 | Brodifacoum | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | bromfenacoum results in increased expression of TXNL1 protein | CTD | PMID:28903499 | choline | multiple interactions | ISO | Txnl1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TXNL1 gene | CTD | PMID:20938992 | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of TXNL1 mRNA | CTD | PMID:27594783 | clobetasol | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Clobetasol results in increased expression of TXNL1 mRNA | CTD | PMID:27462272 | clofibrate | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Clofibrate affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | clofibrate | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Clofibrate results in increased expression of TXNL1 mRNA | CTD | PMID:17585979 | cobalt dichloride | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | cobaltous chloride results in increased expression of TXNL1 mRNA | CTD | PMID:24386269 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of TXNL1 mRNA | CTD | PMID:19320972 and PMID:19376846 | copper atom | multiple interactions | EXP | | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA and [NSC 689534 binds to Copper] which results in increased expression of TXNL1 mRNA | CTD | PMID:20971185 and PMID:24690739 | copper(0) | multiple interactions | EXP | | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA and [NSC 689534 binds to Copper] which results in increased expression of TXNL1 mRNA | CTD | PMID:20971185 and PMID:24690739 | copper(II) chloride | increases expression | EXP | | 6480464 | cupric chloride results in increased expression of TXNL1 mRNA | CTD | PMID:17211630 | copper(II) sulfate | increases expression | EXP | | 6480464 | Copper Sulfate results in increased expression of TXNL1 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | EXP | | 6480464 | Cyclosporine results in increased expression of TXNL1 mRNA | CTD | PMID:20106945 and PMID:25562108 | diazinon | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Diazinon affects the expression of TXNL1 mRNA | CTD | PMID:22546817 | dibutyl phthalate | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in decreased expression of TXNL1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Dibutyl Phthalate results in increased expression of TXNL1 mRNA | CTD | PMID:17379624 | diethylstilbestrol | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in decreased expression of TXNL1 protein | CTD | PMID:20932895 | disulfiram | multiple interactions | EXP | | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA | CTD | PMID:24690739 | dorsomorphin | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TXNL1 mRNA | CTD | PMID:27188386 | epoxiconazole | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of TXNL1 mRNA | CTD | PMID:35436446 | ethanol | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Ethanol results in decreased expression of TXNL1 protein | CTD | PMID:23702218 | ethanol | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Ethanol results in increased expression of TXNL1 mRNA | CTD | PMID:30319688 | etoposide | decreases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Etoposide results in decreased expression of TXNL1 protein | CTD | PMID:29733421 | finasteride | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of TXNL1 mRNA | CTD | PMID:24136188 | flutamide | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of TXNL1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Txnl1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TXNL1 gene | CTD | PMID:20938992 | folic acid | decreases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TXNL1 mRNA | CTD | PMID:25629700 | furan | affects binding | ISO | Txnl1 (Rattus norvegicus) | 6480464 | furan binds to TXNL1 protein | CTD | PMID:22240984 | gentamycin | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of TXNL1 mRNA | CTD | PMID:33387578 | glyphosate | decreases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of TXNL1 protein | CTD | PMID:37208198 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of TXNL1 protein | CTD | PMID:32959892 | L-ethionine | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Ethionine affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | L-methionine | multiple interactions | ISO | Txnl1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of TXNL1 gene | CTD | PMID:20938992 | methimazole | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Methimazole results in increased expression of TXNL1 mRNA | CTD | PMID:30047161 | miconazole | decreases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Miconazole results in decreased expression of TXNL1 mRNA | CTD | PMID:22262564 | microcystin RR | decreases expression | EXP | | 6480464 | microcystin RR results in decreased expression of TXNL1 protein | CTD | PMID:19111056 | N-acetyl-L-cysteine | decreases expression | EXP | | 6480464 | Acetylcysteine results in decreased expression of TXNL1 mRNA | CTD | PMID:16084531 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | EXP | | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [arsenite results in increased degradation of TXNL1 protein] | CTD | PMID:19349280 | N-nitrosodiethylamine | multiple interactions | ISO | Txnl1 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TXNL1 mRNA | CTD | PMID:20360939 | N-nitrosomorpholine | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | N-nitrosomorpholine results in increased expression of TXNL1 protein | CTD | PMID:19716841 | nefazodone | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | nefazodone results in increased expression of TXNL1 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | EXP | | 6480464 | Nickel results in decreased expression of TXNL1 mRNA | CTD | PMID:24768652 and PMID:25583101 | nickel dichloride | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | nickel chloride affects the expression of TXNL1 mRNA | CTD | PMID:22546817 | nimesulide | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | nimesulide results in increased expression of TXNL1 mRNA | CTD | PMID:24136188 | omeprazole | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of TXNL1 mRNA | CTD | PMID:35430440 | p-chloromercuribenzoic acid | increases expression | EXP | | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of TXNL1 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TXNL1 mRNA | CTD | PMID:27188386 | paracetamol | affects expression | ISO | Txnl1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TXNL1 mRNA | CTD | PMID:17562736 | paraquat | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of TXNL1 protein | CTD | PMID:24521700 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Txnl1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TXNL1 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of TXNL1 mRNA | CTD | PMID:36331819 | phenethyl caffeate | multiple interactions | ISO | Txnl1 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of TXNL1 mRNA | CTD | PMID:20360939 | phenobarbital | affects expression | EXP | | 6480464 | Phenobarbital affects the expression of TXNL1 mRNA | CTD | PMID:19159669 | phosgene | affects expression | ISO | Txnl1 (Mus musculus) | 6480464 | Phosgene affects the expression of TXNL1 mRNA | CTD | PMID:16300373 | pirinixic acid | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | pirinixic acid affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of TXNL1 mRNA | CTD | PMID:22714537 | propiconazole | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | propiconazole results in increased expression of TXNL1 mRNA | CTD | PMID:21278054 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of TXNL1 mRNA | CTD | PMID:30851411 | resveratrol | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | resveratrol results in increased expression of TXNL1 protein | CTD | PMID:25505154 | SB 431542 | multiple interactions | EXP | | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TXNL1 mRNA | CTD | PMID:27188386 | sodium arsenite | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of TXNL1 protein | CTD | PMID:29044176 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of TXNL1 protein | CTD | PMID:30528433 | Soman | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Soman results in increased expression of TXNL1 mRNA | CTD | PMID:19281266 | sulfadimethoxine | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in increased expression of TXNL1 mRNA | CTD | PMID:30047161 | sulindac | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Sulindac results in increased expression of TXNL1 mRNA | CTD | PMID:24136188 | tebuconazole | decreases expression | EXP | | 6480464 | tebuconazole results in decreased expression of TXNL1 mRNA | CTD | PMID:30458266 | tert-butyl hydroperoxide | multiple interactions | EXP | | 6480464 | LGM2605 promotes the reaction [tert-Butylhydroperoxide results in increased expression of TXNL1 mRNA] | CTD | PMID:31627909 | tert-butyl hydroperoxide | increases expression | EXP | | 6480464 | tert-Butylhydroperoxide results in increased expression of TXNL1 mRNA | CTD | PMID:31627909 | tetrachloromethane | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in increased expression of TXNL1 mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Txnl1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TXNL1 mRNA | CTD | PMID:31919559 | thapsigargin | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Thapsigargin results in increased expression of TXNL1 protein | CTD | PMID:35544339 | thioacetamide | affects expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Thioacetamide affects the expression of TXNL1 mRNA | CTD | PMID:19483382 | trichloroethene | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of TXNL1 mRNA | CTD | PMID:19448997 | trichostatin A | increases expression | EXP | | 6480464 | trichostatin A results in increased expression of TXNL1 mRNA | CTD | PMID:24935251 | troglitazone | decreases expression | ISO | Txnl1 (Mus musculus) | 6480464 | troglitazone results in decreased expression of TXNL1 mRNA | CTD | PMID:28973697 | valdecoxib | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | valdecoxib results in increased expression of TXNL1 mRNA | CTD | PMID:24136188 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of TXNL1 mRNA | CTD | PMID:25192806 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of TXNL1 mRNA | CTD | PMID:23179753 more ... | vinclozolin | increases expression | ISO | Txnl1 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of TXNL1 mRNA | CTD | PMID:23869203 | vorinostat | increases expression | EXP | | 6480464 | vorinostat results in increased expression of TXNL1 protein | CTD | PMID:20543569 | | |||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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