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Gene: GSDMD (gasdermin D) Homo sapiens
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Symbol: GSDMD
Name: gasdermin D
Description: Predicted to have phospholipid binding activity. Predicted to be involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta secretion; and pyroptosis. Localizes to the nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DF5L; DFNA5L; FKSG10; FLJ12150; gasdermin domain containing 1; gasdermin domain-containing protein 1; gasdermin-D; GSDMDC1
Orthologs:
Mus musculus (house mouse) : Gsdmd (gasdermin D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gsdmd (gasdermin D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsdmd (gasdermin D)
Pan paniscus (bonobo/pygmy chimpanzee) : GSDMD (gasdermin D)
Canis lupus familiaris (dog) : GSDMD (gasdermin D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsdmd (gasdermin D)
Sus scrofa (pig) : GSDMD (gasdermin D)
Chlorocebus sabaeus (green monkey) : GSDMD (gasdermin D)
Heterocephalus glaber (naked mole-rat) : Gsdmd (gasdermin D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8143,553,207 - 143,563,062 (+)Ensembl
GRCh388143,553,387 - 143,563,062 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,635,383 - 144,645,232 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,711,635 - 144,716,375 (+)NCBINCBI36hg18NCBI36
Build 348144,712,102 - 144,716,372NCBI
Celera8140,945,843 - 140,955,486 (+)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8139,886,817 - 139,896,607 (+)NCBIHuRef
CHM1_18144,675,788 - 144,685,442 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on GSDMD
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1316349
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.