GDF15 Human (+)-taxifolin increases expression EXP 6480464 taxifolin results in increased expression of GDF15 mRNA CTD PMID:17541156 GDF15 Human (-)-demecolcine increases expression EXP 6480464 Demecolcine results in increased expression of GDF15 mRNA CTD PMID:23649840 GDF15 Human (1->4)-beta-D-glucan multiple interactions ISO Gdf15 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GDF15 mRNA CTD PMID:36331819 GDF15 Human (S)-colchicine decreases expression EXP 6480464 Colchicine results in decreased expression of GDF15 mRNA CTD PMID:24211769 GDF15 Human 1,1-dichloroethene increases expression ISO Gdf15 (Mus musculus) 6480464 vinylidene chloride results in increased expression of GDF15 mRNA CTD PMID:26682919 GDF15 Human 1,2-dimethylhydrazine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of GDF15 mRNA CTD PMID:27840820 and PMID:32387197 GDF15 Human 1,2-dimethylhydrazine increases expression ISO Gdf15 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of GDF15 mRNA CTD PMID:22206623 GDF15 Human 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions EXP 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] more ... CTD PMID:23996089 GDF15 Human 17beta-estradiol increases expression ISO Gdf15 (Mus musculus) 6480464 Estradiol results in increased expression of GDF15 mRNA CTD PMID:25210133 GDF15 Human 17beta-estradiol increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Estradiol results in increased expression of GDF15 mRNA CTD PMID:31119341 GDF15 Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of GDF15 mRNA CTD PMID:19619570 more ... GDF15 Human 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of GDF15 mRNA CTD PMID:19167446 GDF15 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA more ... CTD PMID:19619570 more ... GDF15 Human 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression EXP 6480464 Metribolone results in increased expression of GDF15 mRNA CTD PMID:17010196 GDF15 Human 17beta-hydroxy-5alpha-androstan-3-one increases expression EXP 6480464 Dihydrotestosterone results in increased expression of GDF15 mRNA CTD PMID:16523695 GDF15 Human 2,2',4,4'-Tetrabromodiphenyl ether decreases expression EXP 6480464 2 more ... CTD PMID:31675489 GDF15 Human 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:36804509 GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA more ... CTD PMID:19619570 more ... GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of GDF15 mRNA CTD PMID:36370075 GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA CTD PMID:19619570 more ... GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gdf15 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA CTD PMID:21570461 GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Gdf15 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA CTD PMID:22298810 GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA CTD PMID:21215274 and PMID:33387578 GDF15 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA CTD PMID:22298810 GDF15 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether increases expression EXP 6480464 2 more ... CTD PMID:26705709 GDF15 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Gdf15 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 GDF15 Human 2,4-dinitrotoluene affects expression ISO Gdf15 (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of GDF15 mRNA CTD PMID:21346803 GDF15 Human 2,6-dichloroindophenol multiple interactions EXP 6480464 [2 and 6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA CTD PMID:21034357 GDF15 Human 2-acetamidofluorene increases expression ISO Gdf15 (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of GDF15 mRNA CTD PMID:21607683 GDF15 Human 2-butoxyethanol increases expression ISO Gdf15 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of GDF15 mRNA CTD PMID:19812364 GDF15 Human 2-nitrofluorene increases expression ISO Gdf15 (Rattus norvegicus) 6480464 2-nitrofluorene results in increased expression of GDF15 mRNA CTD PMID:14600272 more ... GDF15 Human 2-palmitoylglycerol increases expression EXP 6480464 2-palmitoylglycerol results in increased expression of GDF15 mRNA CTD PMID:37199045 GDF15 Human 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:19692669 GDF15 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Gdf15 (Rattus norvegicus) 6480464 3 more ... CTD PMID:32119087 GDF15 Human 3,3',4,4'-tetrachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:20638727 GDF15 Human 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of GDF15 protein CTD PMID:31675489 GDF15 Human 3,3',5,5'-tetrabromobisphenol A multiple interactions EXP 6480464 [PPARG protein results in increased susceptibility to tetrabromobisphenol A] which results in increased expression of GDF15 mRNA CTD PMID:35734227 GDF15 Human 3,3'-diindolylmethane increases expression EXP 6480464 3 and 3'-diindolylmethane results in increased expression of GDF15 mRNA CTD PMID:15670751 GDF15 Human 3,4-dichloroaniline increases expression ISO Gdf15 (Rattus norvegicus) 6480464 3 and 4-dichloroaniline results in increased expression of GDF15 mRNA CTD PMID:24172598 GDF15 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA CTD PMID:28628672 GDF15 Human 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA CTD PMID:28628672 GDF15 Human 4,4'-sulfonyldiphenol affects methylation ISO Gdf15 (Mus musculus) 6480464 bisphenol S affects the methylation of GDF15 gene CTD PMID:31683443 GDF15 Human 4,4'-sulfonyldiphenol decreases expression ISO Gdf15 (Mus musculus) 6480464 bisphenol S results in decreased expression of GDF15 mRNA CTD PMID:33297965 and PMID:39298647 GDF15 Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO Gdf15 (Rattus norvegicus) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of GDF15 mRNA CTD PMID:14600272 more ... GDF15 Human 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid increases expression EXP 6480464 Am 580 results in increased expression of GDF15 mRNA CTD PMID:16982809 GDF15 Human 4-amino-2,6-dinitrotoluene affects expression ISO Gdf15 (Rattus norvegicus) 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of GDF15 mRNA CTD PMID:21346803 GDF15 Human 4-Hydroxybenzophenone increases expression ISO Gdf15 (Mus musculus) 6480464 4-hydroxybenzophenone results in increased expression of GDF15 mRNA CTD PMID:35476924 GDF15 Human 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of GDF15 mRNA and Fenretinide results in increased expression of GDF15 protein CTD PMID:15958647 and PMID:16671099 GDF15 Human 4-hydroxyphenyl retinamide increases expression ISO Gdf15 (Mus musculus) 6480464 Fenretinide results in increased expression of GDF15 mRNA CTD PMID:28973697 GDF15 Human 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions EXP 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] more ... CTD PMID:23996089 GDF15 Human 5-aza-2'-deoxycytidine increases expression ISO Gdf15 (Mus musculus) 6480464 Decitabine results in increased expression of GDF15 mRNA CTD PMID:27915011 GDF15 Human 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 mRNA] and Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 protein] CTD PMID:18801729 GDF15 Human 5-aza-2'-deoxycytidine affects expression EXP 6480464 Decitabine affects the expression of GDF15 mRNA CTD PMID:17145863 and PMID:23300844 GDF15 Human 5-bromo-2'-deoxyuridine multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 GDF15 Human 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of GDF15 mRNA and Fluorouracil results in increased expression of GDF15 protein CTD PMID:14665630 more ... GDF15 Human 5-fluorouracil multiple interactions EXP 6480464 TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA] CTD PMID:15016801 GDF15 Human 7,12-dimethyltetraphene increases expression ISO Gdf15 (Mus musculus) 6480464 9 more ... CTD PMID:32553695 GDF15 Human 8-Br-cAMP increases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF15 mRNA CTD PMID:22079614 GDF15 Human 9-cis-retinoic acid increases expression EXP 6480464 Alitretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 GDF15 Human [6]-Shogaol increases expression EXP 6480464 shogaol results in increased expression of GDF15 mRNA CTD PMID:25148906 GDF15 Human aceclofenac increases expression EXP 6480464 aceclofenac results in increased expression of GDF15 protein CTD PMID:15555568 GDF15 Human aceclofenac increases expression ISO Gdf15 (Mus musculus) 6480464 aceclofenac results in increased expression of GDF15 mRNA CTD PMID:18076062 GDF15 Human acetamide increases expression ISO Gdf15 (Rattus norvegicus) 6480464 acetamide results in increased expression of GDF15 mRNA CTD PMID:31881176 GDF15 Human acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of GDF15 mRNA and Aspirin results in increased expression of GDF15 protein CTD PMID:14976132 and PMID:15180942 GDF15 Human acrolein increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Acrolein results in increased expression of GDF15 mRNA CTD PMID:38090360 GDF15 Human acrylamide increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Acrylamide results in increased expression of GDF15 mRNA CTD PMID:28959563 GDF15 Human acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of GDF15 mRNA CTD PMID:32763439 and PMID:35690182 GDF15 Human acrylamide increases expression ISO Gdf15 (Mus musculus) 6480464 Acrylamide results in increased expression of GDF15 mRNA CTD PMID:30807115 GDF15 Human actinomycin D multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of GDF15 mRNA and Dactinomycin inhibits the reaction [Resveratrol results in increased expression of GDF15 mRNA] CTD PMID:17257620 and PMID:38460933 GDF15 Human actinomycin D increases expression EXP 6480464 Dactinomycin results in increased expression of GDF15 mRNA CTD PMID:38460933 GDF15 Human adefovir pivoxil increases expression EXP 6480464 adefovir dipivoxil results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human adenine decreases expression EXP 6480464 Adenine results in decreased expression of GDF15 mRNA CTD PMID:24211769 GDF15 Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of GDF15 protein CTD PMID:20106945 GDF15 Human aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of GDF15 mRNA CTD PMID:21632981 more ... GDF15 Human aflatoxin B1 increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of GDF15 mRNA CTD PMID:14600272 more ... GDF15 Human all-trans-4-oxoretinoic acid increases expression EXP 6480464 4-oxoretinoic acid results in increased expression of GDF15 mRNA CTD PMID:15982314 GDF15 Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of GDF15 mRNA CTD PMID:17045167 GDF15 Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin metabolite results in increased expression of GDF15 mRNA and Tretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 and PMID:23830798 GDF15 Human amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of GDF15 mRNA CTD PMID:19774075 and PMID:36586010 GDF15 Human ammonium chloride affects expression ISO Gdf15 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of GDF15 mRNA CTD PMID:16483693 GDF15 Human amphibole asbestos affects expression EXP 6480464 Asbestos and Amphibole affects the expression of GDF15 protein CTD PMID:20855422 GDF15 Human amphotericin B increases expression EXP 6480464 Amphotericin B analog results in increased expression of GDF15 mRNA and Amphotericin B results in increased expression of GDF15 mRNA CTD PMID:28534445 GDF15 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone promotes the reaction [silybin results in increased expression of GDF15 protein] CTD PMID:24440808 GDF15 Human antimycin A increases expression EXP 6480464 Antimycin A results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human arecoline increases expression EXP 6480464 Arecoline results in increased expression of GDF15 mRNA CTD PMID:17682004 GDF15 Human aristolochic acid A multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of GDF15 mRNA CTD PMID:23912714 GDF15 Human aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of GDF15 mRNA CTD PMID:33212167 GDF15 Human arsane decreases expression EXP 6480464 Arsenic results in decreased expression of GDF15 mRNA CTD PMID:12773770 GDF15 Human arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of GDF15 mRNA CTD PMID:12773770 GDF15 Human arsenite(3-) multiple interactions EXP 6480464 arsenite promotes the reaction [G3BP1 protein binds to GDF15 mRNA] CTD PMID:32406909 GDF15 Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GDF15 mRNA CTD PMID:19036111 more ... GDF15 Human atrazine increases expression EXP 6480464 Atrazine results in increased expression of GDF15 mRNA CTD PMID:22378314 GDF15 Human Aurin increases expression EXP 6480464 aurin results in increased expression of GDF15 mRNA CTD PMID:25477506 GDF15 Human azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of GDF15 mRNA CTD PMID:22623647 GDF15 Human azoxystrobin multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 GDF15 Human azoxystrobin increases expression EXP 6480464 azoxystrobin results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human benzene-1,2,4-triol increases expression EXP 6480464 hydroxyhydroquinone results in increased expression of GDF15 mRNA CTD PMID:39245080 GDF15 Human benzo[a]pyrene increases expression ISO Gdf15 (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of GDF15 mRNA and Benzo(a)pyrene results in increased expression of GDF15 mRNA CTD PMID:21569818 more ... GDF15 Human benzo[a]pyrene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA and [Benzo(a)pyrene results in increased activity of AHR protein] which results in increased expression of GDF15 mRNA CTD PMID:27858113 and PMID:32553695 GDF15 Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of GDF15 mRNA CTD PMID:20064835 more ... GDF15 Human benzo[a]pyrene diol epoxide I increases expression EXP 6480464 7 more ... CTD PMID:19150397 more ... GDF15 Human benzo[b]fluoranthene increases expression ISO Gdf15 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of GDF15 mRNA CTD PMID:26377693 GDF15 Human benzo[b]fluoranthene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA CTD PMID:27858113 GDF15 Human Benzo[ghi]perylene increases expression ISO Gdf15 (Mus musculus) 6480464 1 and 12-benzoperylene results in increased expression of GDF15 mRNA CTD PMID:26377693 GDF15 Human Benzo[k]fluoranthene decreases expression ISO Gdf15 (Mus musculus) 6480464 benzo(k)fluoranthene results in decreased expression of GDF15 mRNA CTD PMID:26377693 GDF15 Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of GDF15 mRNA CTD PMID:38218311 GDF15 Human beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of GDF15 mRNA CTD PMID:19737606 GDF15 Human beta-naphthoflavone decreases expression EXP 6480464 beta-Naphthoflavone results in decreased expression of GDF15 mRNA CTD PMID:32858204 GDF15 Human bis(2-chloroethyl) sulfide affects expression ISO Gdf15 (Rattus norvegicus) 6480464 Mustard Gas affects the expression of GDF15 mRNA CTD PMID:15651846 GDF15 Human bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of GDF15 mRNA CTD PMID:25102026 GDF15 Human bis(2-ethylhexyl) phthalate increases expression ISO Gdf15 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of GDF15 mRNA CTD PMID:19850644 GDF15 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA CTD PMID:39150890 GDF15 Human bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of GDF15 mRNA CTD PMID:31163220 GDF15 Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of GDF15 mRNA CTD PMID:20170705 and PMID:30903817 GDF15 Human bisphenol A increases expression ISO Gdf15 (Mus musculus) 6480464 bisphenol A results in increased expression of GDF15 mRNA CTD PMID:32156529 and PMID:33221593 GDF15 Human bisphenol A affects expression ISO Gdf15 (Rattus norvegicus) 6480464 bisphenol A affects the expression of GDF15 mRNA CTD PMID:30903817 GDF15 Human bisphenol A increases secretion EXP 6480464 bisphenol A results in increased secretion of GDF15 protein CTD PMID:27745655 GDF15 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of GDF15 mRNA CTD PMID:25047013 more ... GDF15 Human bisphenol A increases expression ISO Gdf15 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of GDF15 mRNA CTD PMID:25181051 and PMID:35192832 GDF15 Human bisphenol AF increases expression EXP 6480464 bisphenol AF results in increased expression of GDF15 protein CTD PMID:34186270 GDF15 Human bortezomib multiple interactions EXP 6480464 [BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of GDF15 mRNA CTD PMID:25522274 GDF15 Human bortezomib increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Bortezomib results in increased expression of GDF15 mRNA CTD PMID:20830808 GDF15 Human bromoacetate increases expression EXP 6480464 bromoacetate results in increased expression of GDF15 mRNA CTD PMID:19753638 GDF15 Human bromobenzene increases expression ISO Gdf15 (Rattus norvegicus) 6480464 bromobenzene results in increased expression of GDF15 mRNA CTD PMID:32479839 GDF15 Human buta-1,3-diene increases expression ISO Gdf15 (Mus musculus) 6480464 1 and 3-butadiene results in increased expression of GDF15 mRNA CTD PMID:29038090 GDF15 Human butan-1-ol multiple interactions EXP 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA CTD PMID:29432896 GDF15 Human butanal increases expression EXP 6480464 butyraldehyde results in increased expression of GDF15 mRNA CTD PMID:26079696 GDF15 Human Butylbenzyl phthalate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA CTD PMID:39150890 GDF15 Human C60 fullerene decreases expression ISO Gdf15 (Rattus norvegicus) 6480464 fullerene C60 results in decreased expression of GDF15 mRNA CTD PMID:19167457 GDF15 Human cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GDF15 mRNA CTD PMID:31738976 GDF15 Human cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GDF15 mRNA and [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 and PMID:31738976 GDF15 Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of GDF15 mRNA CTD PMID:38382870 GDF15 Human cadmium dichloride increases expression ISO Gdf15 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of GDF15 mRNA CTD PMID:29408670 GDF15 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of GDF15 mRNA CTD PMID:25596134 and PMID:38568856 GDF15 Human cadmium dichloride increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of GDF15 mRNA CTD PMID:19010381 GDF15 Human cadmium dichloride affects expression ISO Gdf15 (Rattus norvegicus) 6480464 Cadmium Chloride affects the expression of GDF15 mRNA CTD PMID:22110744 GDF15 Human calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of GDF15 mRNA and Calcitriol results in increased expression of GDF15 protein CTD PMID:15386353 and PMID:16523695 GDF15 Human camptothecin increases expression EXP 6480464 Camptothecin results in increased expression of GDF15 mRNA CTD PMID:38460933 GDF15 Human cannabidiol increases expression ISO Gdf15 (Mus musculus) 6480464 Cannabidiol results in increased expression of GDF15 mRNA CTD PMID:21542829 GDF15 Human cannabidiol multiple interactions EXP 6480464 [Dronabinol co-treated with Cannabidiol] results in increased expression of GDF15 mRNA CTD PMID:26504004 GDF15 Human cannabidiol increases expression EXP 6480464 Cannabidiol results in increased expression of GDF15 mRNA CTD PMID:26504004 and PMID:33244087 GDF15 Human capsaicin multiple interactions EXP 6480464 [CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA] more ... CTD PMID:20110283 GDF15 Human capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of GDF15 protein CTD PMID:20110283 GDF15 Human capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of GDF15 mRNA CTD PMID:20110283 GDF15 Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of GDF15 mRNA CTD PMID:25979313 GDF15 Human carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of GDF15 mRNA CTD PMID:24389112 GDF15 Human carbon nanotube increases expression ISO Gdf15 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 GDF15 Human carbon nanotube decreases expression ISO Gdf15 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 GDF15 Human carbonyl cyanide p-trifluoromethoxyphenylhydrazone increases expression EXP 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA CTD PMID:16039398 GDF15 Human cefaloridine decreases expression ISO Gdf15 (Rattus norvegicus) 6480464 Cephaloridine results in decreased expression of GDF15 mRNA CTD PMID:18500788 GDF15 Human celastrol increases expression EXP 6480464 celastrol results in increased expression of GDF15 mRNA CTD PMID:17010675 GDF15 Human celecoxib multiple interactions EXP 6480464 [Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA more ... CTD PMID:17257745 more ... GDF15 Human celecoxib increases expression EXP 6480464 Celecoxib results in increased expression of GDF15 and Celecoxib results in increased expression of GDF15 mRNA CTD PMID:17257745 more ... GDF15 Human chlordecone decreases expression ISO Gdf15 (Mus musculus) 6480464 Chlordecone results in decreased expression of GDF15 mRNA CTD PMID:33711761 GDF15 Human chloroacetaldehyde increases expression EXP 6480464 chloroacetaldehyde results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human chloropicrin increases expression EXP 6480464 chloropicrin results in increased expression of GDF15 mRNA CTD PMID:26352163 GDF15 Human chloroprene increases expression ISO Gdf15 (Mus musculus) 6480464 Chloroprene results in increased expression of GDF15 mRNA CTD PMID:23125180 GDF15 Human chlorpromazine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Chlorpromazine results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human chlorpyrifos multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 GDF15 Human chromium(6+) affects expression ISO Gdf15 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of GDF15 mRNA CTD PMID:28472532 GDF15 Human chromium(6+) multiple interactions EXP 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GDF15 mRNA CTD PMID:38479592 GDF15 Human chrysene decreases expression ISO Gdf15 (Mus musculus) 6480464 chrysene results in decreased expression of GDF15 mRNA CTD PMID:26377693 GDF15 Human chrysene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA CTD PMID:27858113 GDF15 Human cidofovir anhydrous increases expression EXP 6480464 Cidofovir results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human ciguatoxin CTX1B affects expression ISO Gdf15 (Mus musculus) 6480464 Ciguatoxins affects the expression of GDF15 mRNA CTD PMID:18353800 GDF15 Human cisplatin multiple interactions EXP 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of GDF15 mRNA] and Folic Acid affects the reaction [Cisplatin affects the expression of GDF15 mRNA] CTD PMID:16898872 and PMID:21858171 GDF15 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of GDF15 mRNA CTD PMID:21532991 more ... GDF15 Human cisplatin affects expression EXP 6480464 Cisplatin affects the expression of GDF15 mRNA CTD PMID:23300844 GDF15 Human cisplatin increases expression ISO Gdf15 (Mus musculus) 6480464 Cisplatin results in increased expression of GDF15 mRNA CTD PMID:21151649 GDF15 Human clodronic acid decreases expression EXP 6480464 Clodronic Acid results in decreased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human clofibrate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA] CTD PMID:17585979 GDF15 Human clothianidin increases expression EXP 6480464 clothianidin results in increased expression of GDF15 mRNA CTD PMID:35690182 GDF15 Human clozapine increases expression EXP 6480464 Clozapine results in increased expression of GDF15 protein CTD PMID:36482696 GDF15 Human cobalt atom multiple interactions EXP 6480464 [tungsten carbide binds to Cobalt] which affects the expression of GDF15 mRNA CTD PMID:20105288 GDF15 Human cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of GDF15 mRNA CTD PMID:20105288 GDF15 Human cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of GDF15 mRNA CTD PMID:19376846 GDF15 Human cobalt dichloride increases expression ISO Gdf15 (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of GDF15 mRNA CTD PMID:24386269 GDF15 Human copper atom multiple interactions ISO Gdf15 (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of GDF15 mRNA CTD PMID:15467011 GDF15 Human copper(0) multiple interactions ISO Gdf15 (Mus musculus) 6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of GDF15 mRNA CTD PMID:15467011 GDF15 Human copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of GDF15 mRNA CTD PMID:19549813 GDF15 Human cordycepin affects expression EXP 6480464 cordycepin affects the expression of GDF15 mRNA CTD PMID:28099944 GDF15 Human corosolic acid increases expression EXP 6480464 corosolic acid results in increased expression of GDF15 mRNA CTD PMID:37939859 GDF15 Human coumestrol multiple interactions EXP 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA CTD PMID:19167446 GDF15 Human coumestrol decreases expression EXP 6480464 Coumestrol results in decreased expression of GDF15 mRNA CTD PMID:19167446 GDF15 Human crocidolite asbestos increases expression EXP 6480464 Asbestos and Crocidolite results in increased expression of GDF15 mRNA CTD PMID:18687144 GDF15 Human crocidolite asbestos affects expression EXP 6480464 Asbestos and Crocidolite affects the expression of GDF15 mRNA CTD PMID:25757056 GDF15 Human cryptolepine increases expression EXP 6480464 cryptolepine results in increased expression of GDF15 mRNA CTD PMID:16120219 GDF15 Human CU-O LINKAGE increases expression EXP 6480464 cupric oxide results in increased expression of GDF15 mRNA CTD PMID:22077320 GDF15 Human cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA] more ... CTD PMID:14662774 and PMID:18801729 GDF15 Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of GDF15 mRNA CTD PMID:19159671 more ... GDF15 Human cylindrospermopsin increases expression EXP 6480464 cylindrospermopsin results in increased expression of GDF15 mRNA CTD PMID:23726867 and PMID:24921660 GDF15 Human daunorubicin increases expression EXP 6480464 Daunorubicin results in increased expression of GDF15 mRNA CTD PMID:26537877 and PMID:28940058 GDF15 Human decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of GDF15 protein CTD PMID:31675489 GDF15 Human deguelin increases expression EXP 6480464 deguelin results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human dexamethasone decreases expression ISO Gdf15 (Mus musculus) 6480464 Dexamethasone results in decreased expression of GDF15 mRNA CTD PMID:22733784 GDF15 Human dexamethasone multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA CTD PMID:28628672 GDF15 Human dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of GDF15 mRNA CTD PMID:25047013 GDF15 Human diallyl disulfide increases expression EXP 6480464 diallyl disulfide results in increased expression of GDF15 protein CTD PMID:11925476 GDF15 Human diallyl disulfide multiple interactions EXP 6480464 TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein] CTD PMID:11925476 GDF15 Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of GDF15 mRNA CTD PMID:19036111 more ... GDF15 Human dibenz[a,h]anthracene increases expression ISO Gdf15 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 GDF15 Human dibutyl phthalate increases expression ISO Gdf15 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of GDF15 mRNA CTD PMID:21266533 GDF15 Human dibutyl phthalate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA CTD PMID:39150890 GDF15 Human dibutyl phthalate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein CTD PMID:30218697 GDF15 Human dibutyl phthalate decreases expression ISO Gdf15 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of GDF15 mRNA CTD PMID:17361019 and PMID:21266533 GDF15 Human dichloroacetic acid increases expression ISO Gdf15 (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of GDF15 mRNA CTD PMID:28962523 GDF15 Human dichromium trioxide multiple interactions EXP 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 GDF15 Human diclofenac increases expression ISO Gdf15 (Mus musculus) 6480464 Diclofenac results in increased expression of GDF15 mRNA CTD PMID:18076062 GDF15 Human diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of GDF15 protein CTD PMID:15555568 GDF15 Human dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of GDF15 mRNA CTD PMID:28302478 GDF15 Human Didecyldimethylammonium increases expression EXP 6480464 didecyldimethylammonium results in increased expression of GDF15 mRNA CTD PMID:32763356 GDF15 Human dieldrin affects methylation ISO Gdf15 (Mus musculus) 6480464 Dieldrin affects the methylation of GDF15 gene CTD PMID:38995845 GDF15 Human diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of GDF15 mRNA CTD PMID:33545341 GDF15 Human diethyl phthalate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA CTD PMID:39150890 GDF15 Human diethylstilbestrol increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of GDF15 mRNA CTD PMID:15890375 GDF15 Human dihydroxyacetone decreases expression EXP 6480464 Dihydroxyacetone results in decreased expression of GDF15 mRNA CTD PMID:32506039 GDF15 Human diisobutyl phthalate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA CTD PMID:39150890 GDF15 Human diisononyl phthalate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] affects the expression of GDF15 mRNA CTD PMID:39150890 GDF15 Human dimethylarsinic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 GDF15 Human dimethylarsinous acid increases expression EXP 6480464 dimethylarsinous acid results in increased expression of GDF15 mRNA CTD PMID:23487506 GDF15 Human dioxygen multiple interactions EXP 6480464 Oxygen deficiency inhibits the reaction [darinaparsin results in decreased expression of GDF15 mRNA] CTD PMID:22535156 GDF15 Human dioxygen multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of GDF15 mRNA CTD PMID:33729688 GDF15 Human dioxygen multiple interactions ISO Gdf15 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GDF15 mRNA CTD PMID:30529165 GDF15 Human dioxygen increases expression ISO Gdf15 (Mus musculus) 6480464 Oxygen results in increased expression of GDF15 CTD PMID:28734801 GDF15 Human dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of GDF15 mRNA CTD PMID:26516004 GDF15 Human dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of GDF15 mRNA more ... CTD PMID:25596134 and PMID:28734801 GDF15 Human diquat increases expression ISO Gdf15 (Mus musculus) 6480464 Diquat results in increased expression of GDF15 mRNA CTD PMID:36851058 GDF15 Human disodium selenite increases expression EXP 6480464 Sodium Selenite results in increased expression of GDF15 mRNA CTD PMID:24383545 GDF15 Human diuron increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Diuron metabolite results in increased expression of GDF15 mRNA and Diuron results in increased expression of GDF15 mRNA CTD PMID:24172598 and PMID:25152437 GDF15 Human divanadium pentaoxide increases expression EXP 6480464 vanadium pentoxide results in increased expression of GDF15 mRNA CTD PMID:17459161 GDF15 Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 GDF15 Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of GDF15 mRNA CTD PMID:16705698 GDF15 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of GDF15 mRNA CTD PMID:15205334 more ... GDF15 Human doxorubicin decreases response to substance EXP 6480464 GDF15 protein results in decreased susceptibility to Doxorubicin CTD PMID:22615612 GDF15 Human endosulfan multiple interactions EXP 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA CTD PMID:26159488 GDF15 Human endosulfan increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of GDF15 mRNA CTD PMID:29391264 GDF15 Human Enterolactone multiple interactions EXP 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA CTD PMID:19167446 GDF15 Human entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA CTD PMID:27188386 GDF15 Human entinostat increases expression EXP 6480464 entinostat results in increased expression of GDF15 mRNA CTD PMID:26272509 GDF15 Human epoxiconazole decreases expression ISO Gdf15 (Mus musculus) 6480464 epoxiconazole results in decreased expression of GDF15 mRNA CTD PMID:35436446 GDF15 Human erlotinib hydrochloride multiple interactions EXP 6480464 [Gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein CTD PMID:24979617 GDF15 Human esketamine increases expression EXP 6480464 Esketamine results in increased expression of GDF15 mRNA CTD PMID:38219984 GDF15 Human ethanol increases expression EXP 6480464 Ethanol results in increased expression of GDF15 mRNA CTD PMID:28986285 GDF15 Human ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of GDF15 mRNA CTD PMID:23649840 and PMID:24211769 GDF15 Human etoposide multiple interactions EXP 6480464 Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA] CTD PMID:11895857 GDF15 Human etoposide increases expression EXP 6480464 [Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein more ... CTD PMID:11895857 more ... GDF15 Human fenamidone increases expression ISO Gdf15 (Mus musculus) 6480464 fenamidone results in increased expression of GDF15 mRNA CTD PMID:27029645 GDF15 Human fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human fenofibrate increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Fenofibrate results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human fenpyroximate increases expression EXP 6480464 fenpyroximate results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human flurbiprofen increases expression EXP 6480464 Flurbiprofen results in increased expression of GDF15 protein CTD PMID:21097678 GDF15 Human flurbiprofen multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Flurbiprofen results in increased expression of GDF15 protein] more ... CTD PMID:21097678 GDF15 Human flutamide increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Flutamide results in increased expression of GDF15 mRNA CTD PMID:24793618 GDF15 Human folic acid multiple interactions EXP 6480464 Folic Acid affects the reaction [Cisplatin affects the expression of GDF15 mRNA] CTD PMID:16898872 GDF15 Human folic acid decreases expression ISO Gdf15 (Mus musculus) 6480464 Folic Acid results in decreased expression of GDF15 mRNA CTD PMID:25629700 GDF15 Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of GDF15 mRNA CTD PMID:23649840 GDF15 Human formaldehyde decreases expression EXP 6480464 Formaldehyde results in decreased expression of GDF15 mRNA CTD PMID:28937961 GDF15 Human furan increases expression ISO Gdf15 (Mus musculus) 6480464 furan results in increased expression of GDF15 mRNA CTD PMID:24183702 more ... GDF15 Human furan decreases expression ISO Gdf15 (Rattus norvegicus) 6480464 furan results in decreased expression of GDF15 mRNA CTD PMID:26194646 GDF15 Human furan increases methylation ISO Gdf15 (Rattus norvegicus) 6480464 furan results in increased methylation of GDF15 gene CTD PMID:22079235 GDF15 Human furan multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Bromodeoxyuridine co-treated with furan] results in increased expression of GDF15 mRNA CTD PMID:24910943 GDF15 Human gedunin increases expression EXP 6480464 gedunin results in increased expression of GDF15 mRNA CTD PMID:17010675 GDF15 Human gemcitabine multiple interactions EXP 6480464 [Gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein CTD PMID:24979617 GDF15 Human genistein increases expression ISO Gdf15 (Mus musculus) 6480464 Genistein results in increased expression of GDF15 mRNA CTD PMID:16169203 GDF15 Human genistein increases expression EXP 6480464 Genistein results in increased expression of GDF15 mRNA CTD PMID:22228119 and PMID:26865667 GDF15 Human genistein decreases expression EXP 6480464 Genistein results in decreased expression of GDF15 mRNA CTD PMID:20884965 GDF15 Human gentamycin decreases expression ISO Gdf15 (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of GDF15 mRNA CTD PMID:22061828 GDF15 Human gentamycin increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of GDF15 mRNA CTD PMID:33387578 GDF15 Human gingerol multiple interactions EXP 6480464 GSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein] more ... CTD PMID:18058799 GDF15 Human gingerol increases expression EXP 6480464 gingerol results in increased expression of GDF15 mRNA and gingerol results in increased expression of GDF15 protein CTD PMID:18058799 GDF15 Human glyphosate multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 GDF15 Human graphene oxide decreases expression ISO Gdf15 (Mus musculus) 6480464 graphene oxide results in decreased expression of GDF15 mRNA CTD PMID:33227293 GDF15 Human graphite affects expression ISO Gdf15 (Rattus norvegicus) 6480464 Graphite affects the expression of GDF15 mRNA CTD PMID:29933104 GDF15 Human hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of GDF15 mRNA CTD PMID:20044591 GDF15 Human hydrogen peroxide decreases expression ISO Gdf15 (Mus musculus) 6480464 Hydrogen Peroxide results in decreased expression of GDF15 mRNA CTD PMID:35123994 GDF15 Human hydrogen peroxide multiple interactions EXP 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein CTD PMID:18951874 GDF15 Human hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of GDF15 more ... CTD PMID:12414654 more ... GDF15 Human hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of GDF15 mRNA CTD PMID:23416264 and PMID:31256213 GDF15 Human hydroxyurea increases expression EXP 6480464 Hydroxyurea results in increased expression of GDF15 mRNA CTD PMID:24211769 GDF15 Human ibuprofen increases expression EXP 6480464 Ibuprofen results in increased expression of GDF15 mRNA and Ibuprofen results in increased expression of GDF15 protein CTD PMID:15555568 more ... GDF15 Human ibuprofen multiple interactions EXP 6480464 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ibuprofen results in increased expression of GDF15 protein] more ... CTD PMID:21097678 GDF15 Human ifosfamide increases expression EXP 6480464 Ifosfamide results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human imidacloprid multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 GDF15 Human imidazopyrazole increases expression EXP 6480464 imidazopyrazole analog results in increased expression of GDF15 mRNA CTD PMID:30388846 GDF15 Human indole-3-methanol increases expression EXP 6480464 indole-3-carbinol results in increased expression of GDF15 CTD PMID:15670751 GDF15 Human indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with resveratrol] results in increased expression of GDF15 CTD PMID:15670751 GDF15 Human indometacin increases expression ISO Gdf15 (Mus musculus) 6480464 Indomethacin results in increased expression of GDF15 mRNA CTD PMID:18076062 GDF15 Human indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA CTD PMID:28628672 GDF15 Human indometacin decreases response to substance EXP 6480464 GDF15 protein results in decreased susceptibility to Indomethacin CTD PMID:22615612 GDF15 Human indometacin increases expression EXP 6480464 Indomethacin results in increased expression of GDF15 mRNA and Indomethacin results in increased expression of GDF15 protein CTD PMID:15180942 more ... GDF15 Human inulin multiple interactions ISO Gdf15 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of GDF15 mRNA CTD PMID:36331819 GDF15 Human irinotecan increases expression EXP 6480464 Irinotecan metabolite results in increased expression of GDF15 mRNA and Irinotecan results in increased expression of GDF15 mRNA CTD PMID:15956246 GDF15 Human iron dichloride increases expression EXP 6480464 ferrous chloride results in increased expression of GDF15 mRNA CTD PMID:35984750 GDF15 Human isotretinoin increases expression EXP 6480464 Isotretinoin results in increased expression of GDF15 mRNA CTD PMID:15982314 GDF15 Human ivermectin increases expression ISO Gdf15 (Mus musculus) 6480464 Ivermectin results in increased expression of GDF15 mRNA CTD PMID:28942281 GDF15 Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of GDF15 protein CTD PMID:32959892 GDF15 Human jaspamide multiple interactions EXP 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] CTD PMID:23996089 GDF15 Human jaspamide increases expression EXP 6480464 jasplakinolide results in increased expression of GDF15 mRNA and jasplakinolide results in increased expression of GDF15 protein CTD PMID:23996089 GDF15 Human Lasiocarpine increases expression EXP 6480464 lasiocarpine results in increased expression of GDF15 mRNA CTD PMID:32234424 and PMID:35690182 GDF15 Human latrunculin B multiple interactions EXP 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein] CTD PMID:23996089 GDF15 Human latrunculin B increases expression EXP 6480464 latrunculin B results in increased expression of GDF15 mRNA and latrunculin B results in increased expression of GDF15 protein CTD PMID:23996089 GDF15 Human lead diacetate multiple interactions EXP 6480464 [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 GDF15 Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of GDF15 mRNA CTD PMID:38568856 GDF15 Human leflunomide increases expression EXP 6480464 leflunomide results in increased expression of GDF15 mRNA CTD PMID:28988120 GDF15 Human lidocaine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Lidocaine results in increased expression of GDF15 mRNA CTD PMID:35283115 GDF15 Human lipopolysaccharide decreases expression ISO Gdf15 (Mus musculus) 6480464 Lipopolysaccharides results in decreased expression of GDF15 mRNA CTD PMID:27339419 GDF15 Human lipopolysaccharide multiple interactions EXP 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of GDF15 mRNA more ... CTD PMID:35811015 and PMID:35877022 GDF15 Human lucanthone increases expression EXP 6480464 Lucanthone results in increased expression of GDF15 mRNA CTD PMID:21148553 GDF15 Human manganese atom increases expression EXP 6480464 Manganese results in increased expression of GDF15 mRNA CTD PMID:17175027 GDF15 Human manganese(0) increases expression EXP 6480464 Manganese results in increased expression of GDF15 mRNA CTD PMID:17175027 GDF15 Human manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of GDF15 mRNA CTD PMID:17175027 GDF15 Human menadione affects expression EXP 6480464 Vitamin K 3 affects the expression of GDF15 mRNA CTD PMID:20044591 GDF15 Human menadione increases expression EXP 6480464 Vitamin K 3 results in increased expression of GDF15 mRNA CTD PMID:12414654 GDF15 Human mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of GDF15 mRNA CTD PMID:26272509 GDF15 Human mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA CTD PMID:27188386 GDF15 Human mercury dichloride increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Mercuric Chloride results in increased expression of GDF15 mRNA CTD PMID:16507785 GDF15 Human metacetamol decreases expression ISO Gdf15 (Mus musculus) 6480464 3-hydroxyacetanilide results in decreased expression of GDF15 mRNA CTD PMID:18544908 GDF15 Human metformin increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Metformin results in increased expression of GDF15 mRNA CTD PMID:25596134 GDF15 Human methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of GDF15 mRNA CTD PMID:25290377 GDF15 Human methamphetamine increases expression ISO Gdf15 (Mus musculus) 6480464 Methamphetamine results in increased expression of GDF15 mRNA CTD PMID:36914120 GDF15 Human methamphetamine multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA and GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA] CTD PMID:19564919 and PMID:36914120 GDF15 Human methamphetamine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of GDF15 mRNA CTD PMID:19564919 and PMID:36914120 GDF15 Human methapyrilene increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of GDF15 mRNA CTD PMID:15890375 and PMID:30467583 GDF15 Human methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of GDF15 mRNA CTD PMID:23649840 and PMID:24211769 GDF15 Human methylarsonic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 GDF15 Human methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of GDF15 mRNA CTD PMID:26272509 and PMID:28001369 GDF15 Human methylparaben increases expression EXP 6480464 methylparaben results in increased expression of GDF15 mRNA CTD PMID:31745603 GDF15 Human mitomycin C increases expression EXP 6480464 Mitomycin results in increased expression of GDF15 mRNA CTD PMID:24211769 GDF15 Human Mitotane increases expression EXP 6480464 Mitotane results in increased expression of GDF15 mRNA CTD PMID:22966885 GDF15 Human mitoxantrone increases expression EXP 6480464 Mitoxantrone results in increased expression of GDF15 mRNA CTD PMID:26537877 and PMID:28940058 GDF15 Human mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of GDF15 mRNA CTD PMID:36695872 GDF15 Human N(4)-hydroxycytidine decreases expression ISO Gdf15 (Mus musculus) 6480464 N(4)-hydroxycytidine results in decreased expression of GDF15 mRNA CTD PMID:37748715 GDF15 Human N-acetyl-L-cysteine multiple interactions ISO Gdf15 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA] CTD PMID:35123994 GDF15 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Gdf15 (Mus musculus) 6480464 MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA] CTD PMID:25566086 GDF15 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO Gdf15 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GDF15 mRNA CTD PMID:25566086 GDF15 Human N-ethyl-N-nitrosourea increases expression ISO Gdf15 (Mus musculus) 6480464 Ethylnitrosourea results in increased expression of GDF15 mRNA CTD PMID:19100860 GDF15 Human N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of GDF15 mRNA CTD PMID:24810058 GDF15 Human N-methyl-N'-nitro-N-nitrosoguanidine increases expression EXP 6480464 Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA CTD PMID:12634122 and PMID:12773770 GDF15 Human N-methylformamide increases expression ISO Gdf15 (Mus musculus) 6480464 methylformamide analog results in increased expression of GDF15 mRNA and methylformamide results in increased expression of GDF15 mRNA CTD PMID:17040096 GDF15 Human N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of GDF15 mRNA CTD PMID:21527772 GDF15 Human N-nitrosodiethylamine increases expression ISO Gdf15 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of GDF15 mRNA CTD PMID:19100860 and PMID:21607683 GDF15 Human N-nitrosodimethylamine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased expression of GDF15 mRNA CTD PMID:14600272 and PMID:15890375 GDF15 Human N-nitrosomorpholine increases expression ISO Gdf15 (Rattus norvegicus) 6480464 N-nitrosomorpholine results in increased expression of GDF15 mRNA CTD PMID:19716841 GDF15 Human N-Nitrosopyrrolidine increases expression EXP 6480464 N-Nitrosopyrrolidine results in increased expression of GDF15 mRNA CTD PMID:32234424 and PMID:35690182 GDF15 Human naphthalene increases expression ISO Gdf15 (Mus musculus) 6480464 naphthalene results in increased expression of GDF15 mRNA CTD PMID:18978301 GDF15 Human naphthalene increases expression ISO Gdf15 (Rattus norvegicus) 6480464 naphthalene analog results in increased expression of GDF15 mRNA CTD PMID:24976557 GDF15 Human nevirapine increases expression ISO Gdf15 (Mus musculus) 6480464 Nevirapine results in increased expression of GDF15 mRNA CTD PMID:38636494 GDF15 Human nevirapine multiple interactions ISO Gdf15 (Mus musculus) 6480464 Nevirapine results in increased expression of and results in increased secretion of GDF15 protein CTD PMID:38636494 GDF15 Human nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of GDF15 mRNA CTD PMID:17312168 GDF15 Human nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of GDF15 mRNA CTD PMID:18651567 GDF15 Human niclosamide increases expression EXP 6480464 Niclosamide results in increased expression of GDF15 mRNA CTD PMID:36318118 GDF15 Human NS-398 increases expression EXP 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of GDF15 protein CTD PMID:15180942 GDF15 Human Nutlin-3 increases expression EXP 6480464 nutlin 3 results in increased expression of GDF15 mRNA CTD PMID:16439677 and PMID:38460933 GDF15 Human Nutlin-3 multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of GDF15 mRNA CTD PMID:38460933 GDF15 Human O-methyleugenol increases expression EXP 6480464 methyleugenol results in increased expression of GDF15 mRNA CTD PMID:32234424 and PMID:35690182 GDF15 Human Octicizer multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 GDF15 Human octreotide multiple interactions EXP 6480464 [Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA CTD PMID:17959037 GDF15 Human oxaliplatin increases expression ISO Gdf15 (Rattus norvegicus) 6480464 oxaliplatin results in increased expression of GDF15 mRNA CTD PMID:25729387 GDF15 Human oxaliplatin multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of GDF15 mRNA CTD PMID:25729387 GDF15 Human ozone multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of GDF15 mRNA CTD PMID:34911549 GDF15 Human p-chloromercuribenzoic acid increases expression EXP 6480464 p-Chloromercuribenzoic Acid results in increased expression of GDF15 mRNA CTD PMID:26272509 GDF15 Human p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA CTD PMID:27188386 GDF15 Human paracetamol multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of GDF15 mRNA] CTD PMID:17585979 GDF15 Human paracetamol increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of GDF15 mRNA CTD PMID:33387578 GDF15 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of GDF15 mRNA CTD PMID:29067470 GDF15 Human paracetamol affects expression ISO Gdf15 (Mus musculus) 6480464 Acetaminophen affects the expression of GDF15 mRNA CTD PMID:17562736 GDF15 Human paracetamol increases expression ISO Gdf15 (Mus musculus) 6480464 Acetaminophen results in increased expression of GDF15 mRNA CTD PMID:18544908 and PMID:26056430 GDF15 Human paraquat increases expression EXP 6480464 Paraquat results in increased expression of GDF15 mRNA CTD PMID:20883675 more ... GDF15 Human paraquat increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Paraquat results in increased expression of GDF15 mRNA CTD PMID:32680482 GDF15 Human pentanal increases expression EXP 6480464 pentanal results in increased expression of GDF15 mRNA CTD PMID:26079696 GDF15 Human perfluorodecanoic acid decreases expression EXP 6480464 perfluorodecanoic acid results in decreased expression of GDF15 protein CTD PMID:32916415 GDF15 Human perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of GDF15 mRNA CTD PMID:32588087 GDF15 Human perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of GDF15 mRNA CTD PMID:27153767 GDF15 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GDF15 mRNA more ... CTD PMID:36331819 GDF15 Human perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of GDF15 mRNA and perfluorooctanoic acid results in increased expression of GDF15 protein CTD PMID:26879310 and PMID:36326898 GDF15 Human perfluoroundecanoic acid decreases expression EXP 6480464 perfluoroundecanoic acid results in decreased expression of GDF15 protein CTD PMID:32916415 GDF15 Human phenobarbital multiple interactions ISO Gdf15 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GDF15 mRNA] and NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of GDF15 mRNA] CTD PMID:19482888 and PMID:19850644 GDF15 Human phenobarbital increases expression ISO Gdf15 (Mus musculus) 6480464 Phenobarbital results in increased expression of GDF15 mRNA CTD PMID:19482888 more ... GDF15 Human phenylephrine affects expression EXP 6480464 Phenylephrine affects the expression of GDF15 mRNA CTD PMID:19505289 GDF15 Human phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of GDF15 mRNA CTD PMID:26272509 GDF15 Human phloroglucinol increases expression EXP 6480464 Phloroglucinol analog results in increased expression of GDF15 protein CTD PMID:23178381 GDF15 Human phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein and [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] CTD PMID:23996089 and PMID:30218697 GDF15 Human phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein CTD PMID:23996089 GDF15 Human phosgene affects expression ISO Gdf15 (Mus musculus) 6480464 Phosgene affects the expression of GDF15 mRNA CTD PMID:16300373 GDF15 Human picoxystrobin increases expression EXP 6480464 picoxystrobin results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human pifithrin-alpha hydrobromide multiple interactions EXP 6480464 pifithrin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA] CTD PMID:20064835 GDF15 Human pinosylvin increases expression EXP 6480464 pinosylvin results in increased expression of GDF15 mRNA and pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 GDF15 Human pioglitazone multiple interactions ISO Gdf15 (Mus musculus) 6480464 [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GDF15 mRNA CTD PMID:27935865 GDF15 Human piperonyl butoxide increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Piperonyl Butoxide results in increased expression of GDF15 mRNA CTD PMID:15890375 GDF15 Human pirinixic acid multiple interactions ISO Gdf15 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GDF15 mRNA and PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GDF15 mRNA] CTD PMID:19710929 and PMID:19850644 GDF15 Human pirinixic acid increases expression ISO Gdf15 (Mus musculus) 6480464 pirinixic acid results in increased expression of GDF15 mRNA CTD PMID:18445702 more ... GDF15 Human pirinixic acid increases expression ISO Gdf15 (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of GDF15 mRNA CTD PMID:15890375 GDF15 Human piroxicam multiple interactions EXP 6480464 Cisplatin inhibits the reaction [Piroxicam results in decreased expression of GDF15 mRNA] CTD PMID:21858171 GDF15 Human piroxicam decreases expression EXP 6480464 Piroxicam results in decreased expression of GDF15 mRNA CTD PMID:21858171 GDF15 Human platycodin D increases expression EXP 6480464 platycodin D results in increased expression of GDF15 protein CTD PMID:18804340 GDF15 Human potassium dichromate increases expression EXP 6480464 Potassium Dichromate results in increased expression of GDF15 mRNA CTD PMID:18332044 GDF15 Human progesterone increases expression EXP 6480464 Progesterone results in increased expression of GDF15 mRNA CTD PMID:18037150 GDF15 Human progesterone decreases expression ISO Gdf15 (Mus musculus) 6480464 Progesterone results in decreased expression of GDF15 mRNA CTD PMID:22238285 GDF15 Human progesterone increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Progesterone results in increased expression of GDF15 mRNA CTD PMID:20726854 GDF15 Human progesterone multiple interactions EXP 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA CTD PMID:20660070 GDF15 Human propanal increases expression EXP 6480464 propionaldehyde results in increased expression of GDF15 mRNA CTD PMID:26079696 GDF15 Human prostaglandin J2 increases expression EXP 6480464 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 mRNA and 9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein CTD PMID:14662774 GDF15 Human prostaglandin J2 multiple interactions EXP 6480464 [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein] CTD PMID:14662774 GDF15 Human pterostilbene increases expression EXP 6480464 pterostilbene results in increased expression of GDF15 mRNA CTD PMID:22450950 GDF15 Human pyrimidifen increases expression EXP 6480464 pyrimidifen results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of GDF15 mRNA CTD PMID:15309432 GDF15 Human quercetin increases expression EXP 6480464 Quercetin results in increased expression of GDF15 mRNA CTD PMID:21632981 GDF15 Human resveratrol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with resveratrol] results in increased expression of GDF15 more ... CTD PMID:11895857 more ... GDF15 Human resveratrol increases expression EXP 6480464 [resveratrol results in increased expression of TP53 protein] which results in increased expression of GDF15 protein more ... CTD PMID:11895857 and PMID:17257620 GDF15 Human Ro 31-8220 multiple interactions EXP 6480464 Ro 31-8220 inhibits the reaction [gingerol results in increased expression of GDF15 protein] CTD PMID:18058799 GDF15 Human rotenone increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Rotenone results in increased expression of GDF15 mRNA CTD PMID:27900601 GDF15 Human rotenone increases expression EXP 6480464 Rotenone results in increased expression of GDF15 mRNA CTD PMID:29955902 and PMID:33512557 GDF15 Human rottlerin increases expression EXP 6480464 rottlerin results in increased expression of GDF15 mRNA and rottlerin results in increased expression of GDF15 protein CTD PMID:22410117 GDF15 Human rottlerin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [rottlerin results in increased expression of GDF15 protein] and SB 203580 inhibits the reaction [rottlerin results in increased expression of GDF15 protein] CTD PMID:22410117 GDF15 Human rottlerin affects response to substance EXP 6480464 GDF15 affects the susceptibility to rottlerin CTD PMID:22410117 GDF15 Human S-(1,2-dichlorovinyl)-L-cysteine increases expression EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine results in increased expression of GDF15 mRNA CTD PMID:36576512 GDF15 Human S-(1,2-dichlorovinyl)-L-cysteine multiple interactions EXP 6480464 [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of GDF15 mRNA CTD PMID:35811015 GDF15 Human S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO Gdf15 (Mus musculus) 6480464 Buthionine Sulfoximine results in increased expression of GDF15 mRNA CTD PMID:35123994 GDF15 Human S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO Gdf15 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA] CTD PMID:35123994 GDF15 Human SB 203580 multiple interactions EXP 6480464 [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein] more ... CTD PMID:22410117 more ... GDF15 Human SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 GDF15 Human SCH 23390 multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA CTD PMID:19564919 GDF15 Human Securinine increases expression EXP 6480464 securinine results in increased expression of GDF15 mRNA CTD PMID:32662633 GDF15 Human serpentine asbestos increases expression EXP 6480464 Asbestos and Serpentine results in increased expression of GDF15 mRNA CTD PMID:24160326 GDF15 Human silibinin increases expression EXP 6480464 Silybin results in increased expression of GDF15 mRNA and Silybin results in increased expression of GDF15 protein CTD PMID:24440808 GDF15 Human silibinin multiple interactions EXP 6480464 EGR1 mutant form inhibits the reaction [Silybin results in increased expression of GDF15 protein] more ... CTD PMID:24440808 GDF15 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of GDF15 mRNA CTD PMID:23806026 GDF15 Human silicon dioxide increases expression ISO Gdf15 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of GDF15 mRNA CTD PMID:19073995 more ... GDF15 Human silver atom increases expression ISO Gdf15 (Mus musculus) 6480464 Silver results in increased expression of GDF15 mRNA CTD PMID:27131904 GDF15 Human silver(0) increases expression ISO Gdf15 (Mus musculus) 6480464 Silver results in increased expression of GDF15 mRNA CTD PMID:27131904 GDF15 Human sodium arsenate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 GDF15 Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of GDF15 mRNA CTD PMID:12634122 and PMID:34032870 GDF15 Human sodium arsenite multiple interactions ISO Gdf15 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of GDF15 mRNA CTD PMID:34876320 GDF15 Human sodium arsenite increases expression ISO Gdf15 (Mus musculus) 6480464 sodium arsenite results in increased expression of GDF15 mRNA CTD PMID:16014739 GDF15 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of GDF15 mRNA and sodium arsenite results in increased expression of GDF15 protein CTD PMID:23876855 more ... GDF15 Human sodium arsenite multiple interactions EXP 6480464 [sodium arsenite affects the acetylation of H3-4 protein] which affects the methylation of GDF15 promoter and [sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA CTD PMID:12634122 and PMID:18448484 GDF15 Human sulindac increases expression EXP 6480464 Sulindac results in increased expression of GDF15 mRNA and Sulindac results in increased expression of GDF15 protein CTD PMID:11906190 and PMID:15180942 GDF15 Human sulindac increases expression ISO Gdf15 (Mus musculus) 6480464 Sulindac results in increased expression of GDF15 protein CTD PMID:11984525 GDF15 Human sulindac sulfide multiple interactions EXP 6480464 EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of GDF15 mRNA] CTD PMID:15509713 GDF15 Human sulindac sulfide increases expression ISO Gdf15 (Mus musculus) 6480464 sulindac sulfide results in increased expression of GDF15 mRNA CTD PMID:18076062 GDF15 Human sulindac sulfide increases expression EXP 6480464 sulindac sulfide results in increased expression of GDF15 mRNA and sulindac sulfide results in increased expression of GDF15 protein CTD PMID:11895857 more ... GDF15 Human sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of GDF15 mRNA CTD PMID:31533062 GDF15 Human T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of GDF15 mRNA CTD PMID:34581912 GDF15 Human tamoxifen increases expression ISO Gdf15 (Mus musculus) 6480464 Tamoxifen results in increased expression of GDF15 mRNA CTD PMID:25123088 GDF15 Human tamoxifen decreases response to substance EXP 6480464 GDF15 protein results in decreased susceptibility to Tamoxifen CTD PMID:22615612 GDF15 Human tamoxifen affects expression ISO Gdf15 (Mus musculus) 6480464 Tamoxifen affects the expression of GDF15 mRNA CTD PMID:20937368 GDF15 Human tebufenpyrad increases expression EXP 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human temozolomide increases expression EXP 6480464 Temozolomide results in increased expression of GDF15 mRNA CTD PMID:31758290 GDF15 Human tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of GDF15 mRNA CTD PMID:12414654 GDF15 Human tetrachloromethane increases expression ISO Gdf15 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of GDF15 mRNA CTD PMID:31919559 GDF15 Human tetraphene multiple interactions ISO Gdf15 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of GDF15 mRNA CTD PMID:27858113 GDF15 Human thallium multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [thallium sulfate results in increased abundance of Thallium] which results in increased expression of GDF15 mRNA CTD PMID:39361050 GDF15 Human thallium sulfate multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [thallium sulfate results in increased abundance of Thallium] which results in increased expression of GDF15 mRNA CTD PMID:39361050 GDF15 Human thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of GDF15 mRNA CTD PMID:22378314 GDF15 Human theophylline multiple interactions EXP 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein CTD PMID:18951874 GDF15 Human thiabendazole multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 GDF15 Human thifluzamide increases expression EXP 6480464 thifluzamide results in increased expression of GDF15 mRNA CTD PMID:33512557 GDF15 Human thioacetamide increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of GDF15 mRNA CTD PMID:23411599 and PMID:34492290 GDF15 Human thiostrepton increases expression EXP 6480464 Thiostrepton results in increased expression of GDF15 mRNA CTD PMID:22321511 GDF15 Human thiram increases expression EXP 6480464 Thiram results in increased expression of GDF15 mRNA CTD PMID:38568856 GDF15 Human titanium dioxide increases expression ISO Gdf15 (Mus musculus) 6480464 titanium dioxide results in increased expression of GDF15 mRNA CTD PMID:23557971 GDF15 Human titanium dioxide multiple interactions EXP 6480464 [Vitallium analog binds to titanium dioxide] which results in increased expression of GDF15 mRNA CTD PMID:23825117 GDF15 Human topotecan increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Topotecan results in increased expression of GDF15 mRNA CTD PMID:25729387 GDF15 Human topotecan multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of GDF15 mRNA CTD PMID:25729387 GDF15 Human trans-pinosylvin increases expression EXP 6480464 pinosylvin results in increased expression of GDF15 mRNA and pinosylvin results in increased expression of GDF15 protein CTD PMID:23333577 GDF15 Human tributyl phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 GDF15 Human trichloroethene increases expression ISO Gdf15 (Mus musculus) 6480464 Trichloroethylene results in increased expression of GDF15 mRNA CTD PMID:25549359 GDF15 Human trichloroethene increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of GDF15 mRNA CTD PMID:33387578 GDF15 Human trichostatin A multiple interactions EXP 6480464 [trichostatin A results in increased expression of GDF15 protein] which results in increased cleavage of PARP1 protein more ... CTD PMID:18801729 GDF15 Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of GDF15 mRNA CTD PMID:24935251 GDF15 Human triphenyl phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 GDF15 Human triptonide increases expression ISO Gdf15 (Mus musculus) 6480464 triptonide results in increased expression of GDF15 mRNA CTD PMID:33045310 GDF15 Human tris(2-butoxyethyl) phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 GDF15 Human tris(2-chloroethyl) phosphate multiple interactions ISO Gdf15 (Mus musculus) 6480464 [tris(2-butoxyethyl) phosphate co-treated with IMOL S-140 co-treated with tri-(2-chloroisopropyl)phosphate co-treated with tris(1 and 3-dichloro-2-propyl)phosphate co-treated with triphenyl phosphate co-treated with santicizer 148 co-treated with tris(chloroethyl)phosphate co-treated with 2-ethylhexyldiphenylphosphate co-treated with tributyl phosphate] results in increased expression of GDF15 mRNA CTD PMID:33367866 GDF15 Human troglitazone multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [troglitazone results in increased expression of GDF15 protein] more ... CTD PMID:14662774 GDF15 Human troglitazone increases expression EXP 6480464 troglitazone results in increased expression of GDF15 mRNA and troglitazone results in increased expression of GDF15 protein CTD PMID:14662774 more ... GDF15 Human Tungsten carbide multiple interactions EXP 6480464 [tungsten carbide binds to Cobalt] which affects the expression of GDF15 mRNA CTD PMID:20105288 GDF15 Human tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of GDF15 mRNA CTD PMID:22378314 GDF15 Human urethane increases expression EXP 6480464 Urethane results in increased expression of GDF15 mRNA CTD PMID:28818685 GDF15 Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of GDF15 mRNA CTD PMID:25979313 GDF15 Human valproic acid decreases expression ISO Gdf15 (Rattus norvegicus) 6480464 Valproic Acid results in decreased expression of GDF15 mRNA CTD PMID:35594946 GDF15 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of GDF15 mRNA CTD PMID:23179753 more ... GDF15 Human vincristine increases expression EXP 6480464 Vincristine results in increased expression of GDF15 mRNA CTD PMID:23649840 GDF15 Human wortmannin increases expression EXP 6480464 wortmannin results in increased expression of GDF15 protein CTD PMID:23178381 GDF15 Human zinc atom multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of GDF15 mRNA CTD PMID:18593933 GDF15 Human zinc atom multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 Zinc inhibits the reaction [Zinc deficiency results in increased expression of GDF15 mRNA] CTD PMID:19111725 GDF15 Human zinc atom increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Zinc deficiency results in increased expression of GDF15 mRNA CTD PMID:19111725 GDF15 Human zinc oxide decreases expression ISO Gdf15 (Rattus norvegicus) 6480464 Zinc Oxide results in decreased expression of GDF15 protein CTD PMID:33205376 GDF15 Human zinc pyrithione increases expression EXP 6480464 pyrithione zinc results in increased expression of GDF15 mRNA CTD PMID:21424779 GDF15 Human zinc(0) multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of GDF15 mRNA CTD PMID:18593933 GDF15 Human zinc(0) increases expression ISO Gdf15 (Rattus norvegicus) 6480464 Zinc deficiency results in increased expression of GDF15 mRNA CTD PMID:19111725 GDF15 Human zinc(0) multiple interactions ISO Gdf15 (Rattus norvegicus) 6480464 Zinc inhibits the reaction [Zinc deficiency results in increased expression of GDF15 mRNA] CTD PMID:19111725 GDF15 Human zoledronic acid decreases expression EXP 6480464 zoledronic acid results in decreased expression of GDF15 mRNA CTD PMID:24714768 and PMID:25596134
