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Gene: SP3 (Sp3 transcription factor) Homo sapiens
Symbol: SP3
Name: Sp3 transcription factor
Description: Exhibits RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin and protein-DNA complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp686O1631; GC-binding transcription factor Sp3; specificity protein 3; SPR-2; SPR2; transcription factor Sp3
Mus musculus (house mouse) : Sp3 (trans-acting transcription factor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sp3 (Sp3 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp3 (Sp3 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP3 (Sp3 transcription factor)
Canis lupus familiaris (dog) : SP3 (Sp3 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp3 (Sp3 transcription factor)
Sus scrofa (pig) : SP3 (Sp3 transcription factor)
Chlorocebus sabaeus (green monkey) : SP3 (Sp3 transcription factor)
Heterocephalus glaber (naked mole-rat) : Sp3 (Sp3 transcription factor)
more info ...
Related Pseudogenes: SP3P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2173,880,850 - 173,965,702 (-)Ensembl
GRCh382173,900,775 - 173,965,702 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372174,771,187 - 174,830,430 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362174,481,504 - 174,538,309 (-)NCBINCBI36hg18NCBI36
Celera2168,384,626 - 168,443,931 (-)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2166,650,849 - 166,709,905 (-)NCBIHuRef
CHM1_12174,778,156 - 174,837,417 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SP3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319818
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.