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Gene: KCNN2 (potassium calcium-activated channel subfamily N member 2) Homo sapiens
Symbol: KCNN2
Name: potassium calcium-activated channel subfamily N member 2
Description: Exhibits several functions, including alpha-actinin binding activity; protein homodimerization activity; and small conductance calcium-activated potassium channel activity. Involved in potassium ion transmembrane transport and regulation of potassium ion transmembrane transport. Localizes to the cell surface and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apamin-sensitive small-conductance Ca2+-activated potassium channel; hSK2; KCa2.2; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; SK2; SKCa 2; SKCA2; small conductance calcium-activated potassium channel 2; small conductance calcium-activated potassium channel protein 2
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl5114,055,926 - 114,496,500 (+)Ensembl
GRCh38 Ensembl5114,055,545 - 114,496,500 (+)Ensembl
GRCh385114,055,978 - 114,496,500 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375113,698,016 - 113,832,197 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365113,725,915 - 113,860,096 (+)NCBINCBI36hg18NCBI36
Build 345113,797,125 - 113,860,096NCBI
Celera5109,645,171 - 109,779,247 (+)NCBI
Cytogenetic Map5q22.3NCBI
HuRef5108,880,682 - 109,014,440 (+)NCBIHuRef
CHM1_15113,130,747 - 113,264,917 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNN2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734125
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.