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Gene: BNIP3 (BCL2 interacting protein 3) Homo sapiens
Symbol: BNIP3
Name: BCL2 interacting protein 3
Description: Exhibits GTPase binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including apoptotic signaling pathway; cellular response to mechanical stimulus; and regulation of mitochondrion organization. Localizes to the integral component of mitochondrial outer membrane and nuclear envelope. Biomarker of ductal carcinoma in situ and perinatal necrotizing enterocolitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19kDa interacting protein 3; BCL2/adenovirus E1B interacting protein 3; nineteen kD interacting protein-3; NIP3
Mus musculus (house mouse) : Bnip3 (BCL2/adenovirus E1B interacting protein 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bnip3 (BCL2 interacting protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bnip3 (BCL2 interacting protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BNIP3 (BCL2 interacting protein 3)
Canis lupus familiaris (dog) : BNIP3 (BCL2 interacting protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bnip3 (BCL2 interacting protein 3)
Sus scrofa (pig) : BNIP3 (BCL2 interacting protein 3)
more info ...
Related Pseudogenes: BNIP3P1   BNIP3P10   BNIP3P11   BNIP3P12   BNIP3P14   BNIP3P15   BNIP3P16   BNIP3P17   BNIP3P18   BNIP3P19   BNIP3P2   BNIP3P20   BNIP3P21   BNIP3P22   BNIP3P23   BNIP3P24   BNIP3P25   BNIP3P26   BNIP3P27   BNIP3P28   BNIP3P29   BNIP3P3   BNIP3P30   BNIP3P31   BNIP3P32   BNIP3P33   BNIP3P34   BNIP3P35   BNIP3P36   BNIP3P37   BNIP3P38   BNIP3P39   BNIP3P4   BNIP3P40   BNIP3P42   BNIP3P5   BNIP3P6   BNIP3P8   BNIP3P9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3810131,967,683 - 131,982,013 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710133,781,204 - 133,795,435 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610133,631,194 - 133,645,425 (-)NCBINCBI36hg18NCBI36
Build 3410133,631,193 - 133,645,425NCBI
Celera10127,425,370 - 127,439,605 (-)NCBI
Cytogenetic Map10q26.3NCBI
HuRef10127,330,366 - 127,344,602 (-)NCBIHuRef
CHM1_110134,062,270 - 134,076,612 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BNIP3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350913
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.