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Gene: RCN2 (reticulocalbin 2) Homo sapiens
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Symbol: RCN2
Name: reticulocalbin 2
Description: The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calcium-binding protein ERC-55; E6-binding protein; E6BP; ERC-55; ERC55; reticulocalbin 2, EF-hand calcium binding domain (endoplasmic reticulum calcium-binding protein, 55kD); reticulocalbin-2; TCBP49
Orthologs:
Mus musculus (house mouse) : Rcn2 (reticulocalbin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rcn2 (reticulocalbin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rcn2 (reticulocalbin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RCN2 (reticulocalbin 2)
Canis lupus familiaris (dog) : RCN2 (reticulocalbin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rcn2 (reticulocalbin 2)
Sus scrofa (pig) : RCN2 (reticulocalbin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381576,931,621 - 76,950,260 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371577,223,962 - 77,242,601 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361575,011,171 - 75,029,302 (+)NCBINCBI36hg18NCBI36
Build 341575,011,170 - 75,029,300NCBI
Celera1554,155,320 - 54,173,958 (+)NCBI
Cytogenetic Map15q24.3NCBI
HuRef1553,980,879 - 53,999,495 (+)NCBIHuRef
CHM1_11577,342,151 - 77,360,793 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RCN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733014
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.