PSEN1 (presenilin 1) - Rat Genome Database
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Gene: PSEN1 (presenilin 1) Homo sapiens
Analyze
Symbol: PSEN1
Name: presenilin 1
RGD ID: 731724
HGNC Page HGNC
Description: Exhibits several functions, including ATPase binding activity; PDZ domain binding activity; and aspartic endopeptidase activity, intramembrane cleaving. Involved in several processes, including positive regulation of nitrogen compound metabolic process; proteolysis; and regulation of gene expression. Localizes to several cellular components, including aggresome; endoplasmic reticulum; and nucleus. Implicated in Alzheimer's disease (multiple); Pick's disease; dilated cardiomyopathy 1U; frontotemporal dementia; and hidradenitis suppurativa.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACNINV3; AD3; FAD; presenilin 1 (Alzheimer disease 3); presenilin-1; presenilin-1 isoform I-467; PS-1; PS1; S182
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1473,136,418 - 73,223,691 (+)EnsemblGRCh38hg38GRCh38
GRCh381473,136,436 - 73,223,691 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371473,603,215 - 73,690,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361472,672,932 - 72,756,862 (+)NCBINCBI36hg18NCBI36
Build 341472,684,480 - 72,755,750NCBI
Celera1453,666,429 - 53,753,632 (+)NCBI
Cytogenetic Map14q24.2NCBI
HuRef1453,768,824 - 53,855,913 (+)NCBIHuRef
CHM1_11473,542,049 - 73,629,540 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aminoguanidine  (EXP)
amiodarone  (EXP)
ammonium chloride  (EXP,ISO)
antirheumatic drug  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bisphenol A  (ISO)
bortezomib  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
cannabidiol  (EXP)
carbon nanotube  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
cycloheximide  (EXP)
cypermethrin  (ISO)
cyproconazole  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
diethyldithiocarbamic acid  (EXP)
dioxygen  (ISO)
disodium selenite  (EXP)
diuron  (ISO)
epoxiconazole  (ISO)
fenofibrate  (EXP)
flutamide  (ISO)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
glycine betaine  (ISO)
Goe 6976  (EXP,ISO)
isoflurane  (ISO)
isoniazide  (ISO)
isoprenaline  (ISO)
lead(0)  (EXP,ISO)
lead(2+)  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
maneb  (ISO)
melatonin  (ISO)
methotrexate  (EXP)
methyl methanesulfonate  (EXP)
Methysticin  (ISO)
miconazole  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
nickel atom  (EXP)
nickel dichloride  (ISO)
notoginsenoside R1  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-menthan-3-ol  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
phenobarbital  (ISO)
phorbol 12,13-dibutanoate  (EXP)
progesterone  (ISO)
propiconazole  (ISO)
S-adenosyl-L-homocysteine  (ISO)
sarin  (EXP)
SB 203580  (EXP)
SB 431542  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sulindac sulfide  (EXP)
tauroursodeoxycholic acid  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
Trenbolone  (ISO)
triadimefon  (ISO)
trichostatin A  (EXP)
trilostane  (ISO)
tunicamycin  (EXP,ISO)
urethane  (EXP)
valproic acid  (EXP)
vinclozolin  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of MAPKK activity  (IEA,ISO)
amyloid precursor protein catabolic process  (IBA,IDA,IEA,IGI,IMP,ISO,TAS)
amyloid precursor protein metabolic process  (IDA)
amyloid-beta formation  (IDA,IGI,IMP,ISO)
amyloid-beta metabolic process  (IBA,ISO)
astrocyte activation  (IGI)
astrocyte activation involved in immune response  (IGI)
autophagosome assembly  (IEA,ISO)
autophagy  (ISO)
blood vessel development  (IEA,ISO)
brain development  (ISO)
brain morphogenesis  (IEA,ISO)
Cajal-Retzius cell differentiation  (IEA,ISO)
calcium ion transmembrane transport  (IEA)
calcium ion transport  (IBA)
cell fate specification  (IEA,ISO)
cell-cell adhesion  (IMP)
cellular calcium ion homeostasis  (ISO)
cellular protein metabolic process  (ISO)
cellular response to amyloid-beta  (IGI)
cellular response to DNA damage stimulus  (IDA,ISO)
cerebellum development  (IEA,ISO)
cerebral cortex cell migration  (IEA,ISO)
cerebral cortex development  (ISO)
choline transport  (IEA,ISO)
dorsal/ventral neural tube patterning  (IEA,ISO)
embryonic limb morphogenesis  (IEA,ISO)
endoplasmic reticulum calcium ion homeostasis  (IDA,IGI,IMP,ISO)
ephrin receptor signaling pathway  (TAS)
epithelial cell proliferation  (IEA,ISO)
forebrain development  (ISO)
gene expression  (ISO)
heart development  (ISO)
heart looping  (IEA,ISO)
hematopoietic progenitor cell differentiation  (IEA,ISO)
intracellular signal transduction  (IEA)
L-glutamate import across plasma membrane  (IEA,ISO)
learning or memory  (IGI,ISO,TAS)
locomotion  (ISO)
membrane protein ectodomain proteolysis  (IBA,IDA,ISO)
membrane protein intracellular domain proteolysis  (TAS)
memory  (IGI,ISO)
mitochondrial transport  (IEA,ISO)
modulation of age-related behavioral decline  (IGI,TAS)
myeloid dendritic cell differentiation  (IEA,ISO)
myeloid leukocyte differentiation  (ISO)
negative regulation of apoptotic process  (IBA,IDA,IMP,ISO)
negative regulation of apoptotic signaling pathway  (IEA,ISO)
negative regulation of axonogenesis  (IEA,ISO)
negative regulation of core promoter binding  (IMP)
negative regulation of epidermal growth factor-activated receptor activity  (IEA,ISO)
negative regulation of gene expression  (IGI)
negative regulation of low-density lipoprotein receptor activity  (IGI)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of protein kinase activity  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of transcription by RNA polymerase II  (IMP,ISO)
negative regulation of ubiquitin-dependent protein catabolic process  (IEA,ISO)
negative regulation of ubiquitin-protein transferase activity  (IEA,ISO)
neural retina development  (IEA,ISO)
neurogenesis  (ISO)
neuron apoptotic process  (IEA,ISO)
neuron development  (IEA,ISO)
neuron differentiation  (ISO)
neuron migration  (IEA,ISO)
neuron projection maintenance  (IGI)
neutrophil degranulation  (TAS)
Notch receptor processing  (IBA,IDA,ISO,TAS)
Notch receptor processing, ligand-dependent  (TAS)
Notch signaling pathway  (IEA,ISO)
positive regulation of amyloid fibril formation  (IGI)
positive regulation of apoptotic process  (ISO,TAS)
positive regulation of catalytic activity  (IDA)
positive regulation of coagulation  (IEA,ISO)
positive regulation of dendritic spine development  (IMP)
positive regulation of gene expression  (IGI)
positive regulation of glycolytic process  (IGI)
positive regulation of L-glutamate import across plasma membrane  (IEA,ISO)
positive regulation of MAP kinase activity  (IEA,ISO)
positive regulation of phosphorylation  (IGI)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (IEA,ISO)
positive regulation of protein binding  (IGI)
positive regulation of protein import into nucleus  (IMP)
positive regulation of protein kinase activity  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of receptor recycling  (IEA,ISO)
positive regulation of transcription, DNA-templated  (IMP)
positive regulation of tumor necrosis factor production  (IGI)
post-embryonic development  (IEA,ISO)
protein glycosylation  (IEA,ISO)
protein maturation  (ISO)
protein processing  (IDA,IEA,IGI,IMP,ISO)
protein transport  (IEA,ISO)
proteolysis  (IEA)
regulation of canonical Wnt signaling pathway  (ISO,ISS)
regulation of epidermal growth factor-activated receptor activity  (ISO)
regulation of gene expression  (IGI)
regulation of neuron projection development  (IMP)
regulation of phosphorylation  (IDA)
regulation of protein binding  (ISO)
regulation of resting membrane potential  (IEA,ISO)
regulation of synaptic plasticity  (IEA,ISO)
regulation of synaptic transmission, glutamatergic  (IEA,ISO)
response to oxidative stress  (IEA,ISO)
segmentation  (ISO)
sequestering of calcium ion  (IEA,ISO)
skeletal system morphogenesis  (IEA,ISO)
skin morphogenesis  (IEA,ISO)
smooth endoplasmic reticulum calcium ion homeostasis  (IBA,ISO)
somitogenesis  (IEA,ISO)
synapse organization  (IGI)
synaptic vesicle targeting  (IEA,ISO)
T cell activation involved in immune response  (IEA,ISO)
T cell receptor signaling pathway  (IEA,ISO)
thymus development  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Abnormal brain FDG positron emission tomography  (IAGP)
Abnormal lower motor neuron morphology  (IAGP)
Abnormal social behavior  (IAGP)
Abnormality of extrapyramidal motor function  (IAGP)
Abnormality of neutrophils  (IAGP)
Abnormality of the cerebral white matter  (IAGP)
Abnormality of vision  (IAGP)
Abulia  (IAGP)
Acne inversa  (IAGP)
Adult onset  (IAGP)
Aggressive behavior  (IAGP)
Agitation  (IAGP)
Agnosia  (IAGP)
Alexia  (IAGP)
Alzheimer disease  (IAGP)
Amyotrophic lateral sclerosis  (IAGP)
Anomia  (IAGP)
Anxiety  (IAGP)
Apathy  (IAGP)
Aphasia  (IAGP)
Apraxia  (IAGP)
Astrocytosis  (IAGP)
Ataxia  (IAGP)
Autosomal dominant inheritance  (IAGP)
Babinski sign  (IAGP)
Bilateral tonic-clonic seizure  (IAGP)
Brain atrophy  (IAGP)
Cerebral cortical atrophy  (IAGP)
Chronic furunculosis  (IAGP)
Collectionism  (IAGP)
Confusion  (IAGP)
Congestive heart failure  (IAGP)
Dementia  (IAGP)
Deposits immunoreactive to beta-amyloid protein  (IAGP)
Depressivity  (IAGP)
Dilated cardiomyopathy  (IAGP)
Disinhibition  (IAGP)
Dysarthria  (IAGP)
Dyscalculia  (IAGP)
Dysgraphia  (IAGP)
Dyslexia  (IAGP)
Dysphagia  (IAGP)
Dysphasia  (IAGP)
Dystonia  (IAGP)
Echolalia  (IAGP)
EEG with continuous slow activity  (IAGP)
Elevated serum creatine kinase  (IAGP)
EMG abnormality  (IAGP)
Emotional blunting  (IAGP)
Fasciculations  (IAGP)
Finger agnosia  (IAGP)
Frontal lobe dementia  (IAGP)
Frontotemporal cerebral atrophy  (IAGP)
Frontotemporal dementia  (IAGP)
Gait disturbance  (IAGP)
Gliosis  (IAGP)
Grammar-specific speech disorder  (IAGP)
Hallucinations  (IAGP)
Heterogeneous  (IAGP)
Hyperorality  (IAGP)
Hyperreflexia  (IAGP)
Hypertonia  (IAGP)
Inappropriate behavior  (IAGP)
Inappropriate laughter  (IAGP)
Inappropriate sexual behavior  (IAGP)
Intellectual disability  (IAGP)
Irritability  (IAGP)
Lack of insight  (IAGP)
Language impairment  (IAGP)
Lipoatrophy  (IAGP)
Loss of speech  (IAGP)
Lower limb hyperreflexia  (IAGP)
Memory impairment  (IAGP)
Motor aphasia  (IAGP)
Mutism  (IAGP)
Myoclonus  (IAGP)
Myopathy  (IAGP)
Neurofibrillary tangles  (IAGP)
Neuronal loss in central nervous system  (IAGP)
Oculomotor apraxia  (IAGP)
Optic ataxia  (IAGP)
Palmoplantar keratoderma  (IAGP)
Parkinsonism  (IAGP)
Perifolliculitis  (IAGP)
Perseveration  (IAGP)
Personality changes  (IAGP)
Polyphagia  (IAGP)
Poor speech  (IAGP)
Primitive reflex  (IAGP)
Psychosis  (IAGP)
Rapidly progressive  (IAGP)
Recurrent cutaneous abscess formation  (IAGP)
Restlessness  (IAGP)
Restrictive behavior  (IAGP)
Seizure  (IAGP)
Semantic dementia  (IAGP)
Senile plaques  (IAGP)
Sensorineural hearing impairment  (IAGP)
Spastic tetraparesis  (IAGP)
Spoken Word Recognition Deficit  (IAGP)
Sporadic  (IAGP)
Stereotypy  (IAGP)
Syncope  (IAGP)
Temporal cortical atrophy  (IAGP)
Thickened nuchal skin fold  (IAGP)
Upper motor neuron dysfunction  (IAGP)
Visual agnosia  (IAGP)
References

Additional References at PubMed
PMID:1303289   PMID:1349467   PMID:1411576   PMID:7550356   PMID:7623584   PMID:7651536   PMID:8125298   PMID:8574969   PMID:8634711   PMID:8634712   PMID:8641442   PMID:8733303  
PMID:8742474   PMID:8755489   PMID:8804415   PMID:8837617   PMID:8875251   PMID:8878479   PMID:8922407   PMID:8931704   PMID:9007311   PMID:9013610   PMID:9052708   PMID:9070286  
PMID:9073509   PMID:9144240   PMID:9172170   PMID:9173929   PMID:9223106   PMID:9223340   PMID:9225696   PMID:9246482   PMID:9298817   PMID:9298903   PMID:9384602   PMID:9436726  
PMID:9437013   PMID:9443865   PMID:9452432   PMID:9485372   PMID:9507958   PMID:9521418   PMID:9521423   PMID:9544835   PMID:9632714   PMID:9689133   PMID:9712537   PMID:9719376  
PMID:9738936   PMID:9771752   PMID:9831473   PMID:9833068   PMID:9851443   PMID:9851450   PMID:9852041   PMID:9915968   PMID:10025789   PMID:10037471   PMID:10069390   PMID:10077672  
PMID:10090481   PMID:10092585   PMID:10200054   PMID:10206644   PMID:10206645   PMID:10208579   PMID:10208590   PMID:10341227   PMID:10366599   PMID:10369872   PMID:10401002   PMID:10439444  
PMID:10441572   PMID:10446169   PMID:10447269   PMID:10508860   PMID:10521466   PMID:10527805   PMID:10533070   PMID:10545183   PMID:10551805   PMID:10587643   PMID:10593990   PMID:10631141  
PMID:10635315   PMID:10801777   PMID:10801983   PMID:10805794   PMID:10811883   PMID:10854253   PMID:10891589   PMID:10899933   PMID:10993067   PMID:10997338   PMID:11027672   PMID:11030797  
PMID:11076969   PMID:11083918   PMID:11094121   PMID:11104755   PMID:11110974   PMID:11129109   PMID:11140838   PMID:11168528   PMID:11193155   PMID:11200686   PMID:11226248   PMID:11389157  
PMID:11436125   PMID:11444983   PMID:11504726   PMID:11518718   PMID:11524469   PMID:11568920   PMID:11710891   PMID:11719200   PMID:11738826   PMID:11744687   PMID:11755019   PMID:11757955  
PMID:11775232   PMID:11799129   PMID:11827452   PMID:11836371   PMID:11847232   PMID:11876645   PMID:11880515   PMID:11891288   PMID:11904448   PMID:11905990   PMID:11912199   PMID:11920851  
PMID:11927360   PMID:11943765   PMID:11953314   PMID:11973477   PMID:11987239   PMID:12048239   PMID:12048259   PMID:12050157   PMID:12056836   PMID:12058025   PMID:12070348   PMID:12111439  
PMID:12112163   PMID:12119298   PMID:12121968   PMID:12147673   PMID:12192622   PMID:12196555   PMID:12198112   PMID:12207970   PMID:12214059   PMID:12218704   PMID:12230303   PMID:12297048  
PMID:12297508   PMID:12354302   PMID:12374741   PMID:12377771   PMID:12413003   PMID:12435726   PMID:12444985   PMID:12460547   PMID:12470641   PMID:12471034   PMID:12477932   PMID:12484344  
PMID:12493737   PMID:12495082   PMID:12508121   PMID:12522139   PMID:12535650   PMID:12551931   PMID:12603837   PMID:12609057   PMID:12629514   PMID:12639958   PMID:12660785   PMID:12668610  
PMID:12679784   PMID:12686406   PMID:12740439   PMID:12742741   PMID:12752408   PMID:12763021   PMID:12787561   PMID:12794186   PMID:12805290   PMID:12817569   PMID:12821663   PMID:12843241  
PMID:12846562   PMID:12850546   PMID:12885573   PMID:12885769   PMID:12901838   PMID:12925374   PMID:12935881   PMID:12960155   PMID:13678586   PMID:14502086   PMID:14504279   PMID:14515347  
PMID:14550564   PMID:14572442   PMID:14576165   PMID:14581682   PMID:14590205   PMID:14625299   PMID:14645205   PMID:14702039   PMID:14717705   PMID:14741365   PMID:14756819   PMID:14759258  
PMID:14769392   PMID:14993906   PMID:15003276   PMID:15004326   PMID:15037614   PMID:15087467   PMID:15109302   PMID:15115757   PMID:15119739   PMID:15122701   PMID:15123598   PMID:15123653  
PMID:15147205   PMID:15159497   PMID:15192701   PMID:15205973   PMID:15209417   PMID:15210705   PMID:15240571   PMID:15257293   PMID:15272895   PMID:15274632   PMID:15294909   PMID:15308304  
PMID:15322084   PMID:15322109   PMID:15340889   PMID:15341515   PMID:15345747   PMID:15448688   PMID:15469450   PMID:15474363   PMID:15476169   PMID:15480851   PMID:15480879   PMID:15489334  
PMID:15534001   PMID:15534188   PMID:15534260   PMID:15537629   PMID:15549135   PMID:15569674   PMID:15591316   PMID:15622541   PMID:15629423   PMID:15703411   PMID:15721744   PMID:15722417  
PMID:15732120   PMID:15743767   PMID:15764367   PMID:15764596   PMID:15776278   PMID:15843437   PMID:15851849   PMID:15866047   PMID:15905180   PMID:15908021   PMID:15917251   PMID:15936948  
PMID:15946688   PMID:15951428   PMID:15975068   PMID:15975090   PMID:16006137   PMID:16007100   PMID:16014629   PMID:16046406   PMID:16116115   PMID:16126725   PMID:16128583   PMID:16135086  
PMID:16139258   PMID:16234243   PMID:16234244   PMID:16267640   PMID:16305624   PMID:16344340   PMID:16344560   PMID:16376112   PMID:16388371   PMID:16401857   PMID:16407539   PMID:16423463  
PMID:16511561   PMID:16569643   PMID:16574645   PMID:16605258   PMID:16620965   PMID:16628450   PMID:16630834   PMID:16641999   PMID:16735229   PMID:16756946   PMID:16813565   PMID:16814287  
PMID:16815845   PMID:16846981   PMID:16897084   PMID:16908988   PMID:16916581   PMID:16938285   PMID:16941492   PMID:16952411   PMID:16959576   PMID:17081983   PMID:17088253   PMID:17099291  
PMID:17108181   PMID:17158800   PMID:17192785   PMID:17207965   PMID:17210196   PMID:17229472   PMID:17259169   PMID:17268504   PMID:17268505   PMID:17309564   PMID:17320044   PMID:17349981  
PMID:17360711   PMID:17366635   PMID:17389597   PMID:17401156   PMID:17405936   PMID:17412506   PMID:17428795   PMID:17431506   PMID:17489097   PMID:17502474   PMID:17507029   PMID:17553989  
PMID:17560791   PMID:17573346   PMID:17588625   PMID:17594345   PMID:17627113   PMID:17630980   PMID:17632280   PMID:17645236   PMID:17718701   PMID:17719017   PMID:17852592   PMID:17911105  
PMID:17942194   PMID:17962197   PMID:17968601   PMID:17986144   PMID:18024701   PMID:18028191   PMID:18090315   PMID:18174159   PMID:18201567   PMID:18239458   PMID:18293935   PMID:18299393  
PMID:18314228   PMID:18317569   PMID:18320103   PMID:18350357   PMID:18376127   PMID:18403054   PMID:18430735   PMID:18437002   PMID:18445230   PMID:18479822   PMID:18525293   PMID:18579078  
PMID:18580586   PMID:18587238   PMID:18591429   PMID:18637955   PMID:18667258   PMID:18667537   PMID:18706205   PMID:18762245   PMID:18790549   PMID:18801744   PMID:18830724   PMID:18842294  
PMID:18957849   PMID:18971484   PMID:18996842   PMID:19001354   PMID:19012753   PMID:19015863   PMID:19017784   PMID:19036728   PMID:19111578   PMID:19114997   PMID:19221408   PMID:19232479  
PMID:19260824   PMID:19272356   PMID:19276550   PMID:19276551   PMID:19292975   PMID:19407341   PMID:19490893   PMID:19650138   PMID:19667325   PMID:19675248   PMID:19682973   PMID:19710022  
PMID:19796846   PMID:19797784   PMID:19833411   PMID:19834068   PMID:19849793   PMID:19853643   PMID:19885829   PMID:19889475   PMID:19889971   PMID:19924286   PMID:20005821   PMID:20008141  
PMID:20008660   PMID:20009122   PMID:20018629   PMID:20034479   PMID:20036849   PMID:20052609   PMID:20106965   PMID:20158511   PMID:20160458   PMID:20164095   PMID:20168091   PMID:20219685  
PMID:20237298   PMID:20299451   PMID:20301340   PMID:20301414   PMID:20301486   PMID:20301678   PMID:20307581   PMID:20379614   PMID:20388456   PMID:20399254   PMID:20413895   PMID:20418378  
PMID:20445063   PMID:20445084   PMID:20456003   PMID:20460383   PMID:20481270   PMID:20484632   PMID:20534741   PMID:20541250   PMID:20594621   PMID:20677014   PMID:20696212   PMID:20701429  
PMID:20724034   PMID:20806406   PMID:20811458   PMID:20847418   PMID:20847436   PMID:20858963   PMID:20858974   PMID:20880607   PMID:20929727   PMID:20970889   PMID:21033353   PMID:21115843  
PMID:21143716   PMID:21144619   PMID:21163940   PMID:21238544   PMID:21277951   PMID:21296022   PMID:21297272   PMID:21305049   PMID:21323574   PMID:21422519   PMID:21545304   PMID:21559374  
PMID:21621296   PMID:21656036   PMID:21726674   PMID:21762767   PMID:21784978   PMID:21852538   PMID:21860086   PMID:21873635   PMID:21914807   PMID:21919498   PMID:21929538   PMID:21951279  
PMID:21959359   PMID:21988832   PMID:22014620   PMID:22027014   PMID:22036569   PMID:22045484   PMID:22045496   PMID:22074918   PMID:22133015   PMID:22214483   PMID:22230888   PMID:22297172  
PMID:22311977   PMID:22312439   PMID:22375059   PMID:22393443   PMID:22426017   PMID:22443192   PMID:22459153   PMID:22461631   PMID:22503161   PMID:22505025   PMID:22508690   PMID:22529981  
PMID:22561329   PMID:22572737   PMID:22607268   PMID:22622421   PMID:22634208   PMID:22689582   PMID:22710270   PMID:22753898   PMID:22755192   PMID:22766738   PMID:22771797   PMID:22810102  
PMID:22879628   PMID:22882713   PMID:22939629   PMID:22975585   PMID:23026200   PMID:23046926   PMID:23064434   PMID:23096707   PMID:23114514   PMID:23123781   PMID:23134660   PMID:23137948  
PMID:23137949   PMID:23138650   PMID:23152628   PMID:23209290   PMID:23237322   PMID:23244427   PMID:23271316   PMID:23291095   PMID:23337342   PMID:23371443   PMID:23379308   PMID:23380992  
PMID:23396974   PMID:23415546   PMID:23474291   PMID:23483213   PMID:23489366   PMID:23575824   PMID:23579331   PMID:23583593   PMID:23584198   PMID:23585889   PMID:23624206   PMID:23638752  
PMID:23660953   PMID:23674689   PMID:23707529   PMID:23740836   PMID:23792692   PMID:23794287   PMID:23827013   PMID:23850332   PMID:23884042   PMID:23904197   PMID:23905998   PMID:23942054  
PMID:23948899   PMID:23990795   PMID:24012003   PMID:24029002   PMID:24052308   PMID:24121961   PMID:24138759   PMID:24145027   PMID:24192669   PMID:24217025   PMID:24217950   PMID:24239249  
PMID:24239350   PMID:24252417   PMID:24256243   PMID:24315833   PMID:24344333   PMID:24399296   PMID:24410857   PMID:24416243   PMID:24495933   PMID:24569455   PMID:24582897   PMID:24650794  
PMID:24704512   PMID:24718101   PMID:24737487   PMID:24816373   PMID:24839116   PMID:24880964   PMID:24927704   PMID:24928006   PMID:25034304   PMID:25281826   PMID:25323700   PMID:25352452  
PMID:25394380   PMID:25429133   PMID:25458374   PMID:25471389   PMID:25542424   PMID:25580592   PMID:25595498   PMID:25614624   PMID:25638532   PMID:25673856   PMID:25707991   PMID:25730041  
PMID:25737280   PMID:25741723   PMID:25796185   PMID:25812849   PMID:25883527   PMID:25893612   PMID:25918421   PMID:25959826   PMID:25998117   PMID:26025363   PMID:26094765   PMID:26112421  
PMID:26121081   PMID:26145164   PMID:26159191   PMID:26159201   PMID:26200696   PMID:26214276   PMID:26280335   PMID:26312828   PMID:26337232   PMID:26462451   PMID:26496610   PMID:26549787  
PMID:26559975   PMID:26608390   PMID:26678016   PMID:26687948   PMID:26695639   PMID:26743123   PMID:26756738   PMID:26836186   PMID:26871637   PMID:26872378   PMID:26888304   PMID:26902171  
PMID:26925509   PMID:26988102   PMID:27009418   PMID:27036734   PMID:27059953   PMID:27070140   PMID:27135718   PMID:27143420   PMID:27184076   PMID:27196744   PMID:27220847   PMID:27264813  
PMID:27357204   PMID:27388605   PMID:27498054   PMID:27535542   PMID:27601731   PMID:27608597   PMID:27614317   PMID:27743520   PMID:27763550   PMID:27777022   PMID:27793474   PMID:27799753  
PMID:27816212   PMID:27818272   PMID:27836335   PMID:27858713   PMID:27926491   PMID:28008308   PMID:28065263   PMID:28065273   PMID:28069439   PMID:28106563   PMID:28131463   PMID:28132667  
PMID:28193235   PMID:28269784   PMID:28351972   PMID:28502043   PMID:28514442   PMID:28532645   PMID:28532646   PMID:28533411   PMID:28550254   PMID:28554858   PMID:28577205   PMID:28753424  
PMID:28815510   PMID:28821390   PMID:28841371   PMID:28987665   PMID:28994238   PMID:29061364   PMID:29078389   PMID:29091718   PMID:29125487   PMID:29153989   PMID:29175279   PMID:29439343  
PMID:29466804   PMID:29611543   PMID:29880815   PMID:29968942   PMID:29989545   PMID:30006461   PMID:30040714   PMID:30055028   PMID:30105992   PMID:30158533   PMID:30161272   PMID:30194290  
PMID:30200536   PMID:30289529   PMID:30440121   PMID:30559186   PMID:30560948   PMID:30599314   PMID:30636740   PMID:30745123   PMID:30822634   PMID:31091453   PMID:31153663   PMID:31165862  
PMID:31167792   PMID:31182772   PMID:31217332   PMID:31235344   PMID:31385772   PMID:31386938   PMID:31416668   PMID:31500908   PMID:31522977   PMID:31536960   PMID:31686034   PMID:31697913  
PMID:31764245   PMID:31914229   PMID:31941156   PMID:31944856   PMID:32103039   PMID:32296078   PMID:32296183   PMID:32468481   PMID:32631487   PMID:32857763   PMID:33060197   PMID:33263761  


Genomics

Comparative Map Data
PSEN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1473,136,418 - 73,223,691 (+)EnsemblGRCh38hg38GRCh38
GRCh381473,136,436 - 73,223,691 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371473,603,215 - 73,690,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361472,672,932 - 72,756,862 (+)NCBINCBI36hg18NCBI36
Build 341472,684,480 - 72,755,750NCBI
Celera1453,666,429 - 53,753,632 (+)NCBI
Cytogenetic Map14q24.2NCBI
HuRef1453,768,824 - 53,855,913 (+)NCBIHuRef
CHM1_11473,542,049 - 73,629,540 (+)NCBICHM1_1
Psen1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391283,734,926 - 83,781,869 (+)NCBIGRCm39mm39
GRCm39 Ensembl1283,734,926 - 83,781,973 (+)Ensembl
GRCm381283,688,152 - 83,735,095 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1283,688,152 - 83,735,199 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,029,513 - 85,076,149 (+)NCBIGRCm37mm9NCBIm37
MGSCv361284,578,311 - 84,624,947 (+)NCBImm8
Celera1285,135,054 - 85,181,689 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1238.84NCBI
Psen1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26103,323,014 - 103,375,088 (+)NCBI
Rnor_6.0 Ensembl6107,169,528 - 107,216,798 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06107,169,514 - 107,221,000 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06118,324,910 - 118,373,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46107,737,543 - 107,776,357 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16107,729,188 - 107,781,021 (+)NCBI
Celera6101,163,513 - 101,199,486 (+)NCBICelera
Cytogenetic Map6q24NCBI
Psen1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555232,128,529 - 2,210,737 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555232,128,529 - 2,210,737 (-)NCBIChiLan1.0ChiLan1.0
PSEN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11472,579,024 - 72,663,876 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1472,579,024 - 72,663,876 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01453,718,299 - 53,802,684 (+)NCBIMhudiblu_PPA_v0panPan3
PSEN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl846,495,624 - 46,569,532 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1846,495,551 - 46,569,532 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Psen1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364882,464,623 - 2,528,807 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSEN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl796,478,181 - 96,569,132 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1796,478,179 - 96,567,884 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27102,265,830 - 102,360,301 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q12-q26NCBI
PSEN1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12450,394,310 - 50,476,521 (+)NCBI
ChlSab1.1 Ensembl2450,405,590 - 50,472,132 (+)Ensembl
Psen1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473428,200,358 - 28,272,684 (-)NCBI

Position Markers
D14S43  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371474,943,685 - 74,943,869UniSTSGRCh37
Build 361474,013,438 - 74,013,622RGDNCBI36
Celera1454,982,072 - 54,982,256RGD
Cytogenetic Map14q24.3UniSTS
HuRef1455,112,163 - 55,112,321UniSTS
Marshfield Genetic Map1484.16UniSTS
Marshfield Genetic Map1484.16RGD
Whitehead-YAC Contig Map14 UniSTS
G38136  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,613,349 - 73,613,545UniSTSGRCh37
Build 361472,683,102 - 72,683,298RGDNCBI36
Celera1453,676,631 - 53,676,827RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,779,025 - 53,779,221UniSTS
G38218  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,618,035 - 73,618,231UniSTSGRCh37
Build 361472,687,788 - 72,687,984RGDNCBI36
Celera1453,681,316 - 53,681,512RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,783,711 - 53,783,907UniSTS
G38175  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,635,316 - 73,635,574UniSTSGRCh37
Build 361472,705,069 - 72,705,327RGDNCBI36
Celera1453,698,595 - 53,698,853RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,801,074 - 53,801,332UniSTS
G38215  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,611,092 - 73,611,344UniSTSGRCh37
Build 361472,680,845 - 72,681,097RGDNCBI36
Celera1453,674,374 - 53,674,626RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,776,769 - 53,777,021UniSTS
G38068  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,616,490 - 73,616,740UniSTSGRCh37
Build 361472,686,243 - 72,686,493RGDNCBI36
Celera1453,679,772 - 53,680,022RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,782,167 - 53,782,417UniSTS
SHGC-78932  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,639,753 - 73,640,052UniSTSGRCh37
Build 361472,709,506 - 72,709,805RGDNCBI36
Celera1453,703,032 - 53,703,331RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,805,511 - 53,805,810UniSTS
D14S1438  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,640,288 - 73,640,468UniSTSGRCh37
Build 361472,710,041 - 72,710,221RGDNCBI36
Celera1453,703,567 - 53,703,747RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,806,046 - 53,806,226UniSTS
D14S1439  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,653,502 - 73,653,730UniSTSGRCh37
Build 361472,723,255 - 72,723,483RGDNCBI36
Celera1453,716,733 - 53,716,961RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,818,953 - 53,819,181UniSTS
D14S1440  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,659,462 - 73,659,565UniSTSGRCh37
Build 361472,729,215 - 72,729,318RGDNCBI36
Celera1453,722,693 - 53,722,796RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,824,913 - 53,825,016UniSTS
D14S1442  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,683,907 - 73,684,122UniSTSGRCh37
Build 361472,753,660 - 72,753,875RGDNCBI36
Celera1453,747,138 - 53,747,353RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,849,419 - 53,849,634UniSTS
D14S1264  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,655,166 - 73,655,266UniSTSGRCh37
Build 361472,724,919 - 72,725,019RGDNCBI36
Celera1453,718,397 - 53,718,497RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,820,617 - 53,820,717UniSTS
G38220  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,635,503 - 73,635,664UniSTSGRCh37
GRCh37532,978,411 - 32,978,643UniSTSGRCh37
Build 36533,014,168 - 33,014,400RGDNCBI36
Celera1453,698,782 - 53,698,943UniSTS
Celera532,860,015 - 32,860,247RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,801,261 - 53,801,422UniSTS
HuRef532,947,631 - 32,947,863UniSTS
G38066  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,680,145 - 73,680,345UniSTSGRCh37
Build 361472,749,898 - 72,750,098RGDNCBI36
Celera1453,743,376 - 53,743,576RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,845,657 - 53,845,857UniSTS
SHGC-132632  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,690,075 - 73,690,365UniSTSGRCh37
Build 361472,759,828 - 72,760,118RGDNCBI36
Celera1453,753,308 - 53,753,598RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,855,589 - 53,855,879UniSTS
TNG Radiation Hybrid Map1426432.0UniSTS
PSEN1_232  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,686,255 - 73,687,100UniSTSGRCh37
Build 361472,756,008 - 72,756,853RGDNCBI36
Celera1453,749,488 - 53,750,333RGD
HuRef1453,851,769 - 53,852,614UniSTS
SHGC-36769  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,690,246 - 73,690,377UniSTSGRCh37
Build 361472,759,999 - 72,760,130RGDNCBI36
Celera1453,753,479 - 53,753,610RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,855,760 - 53,855,891UniSTS
GeneMap99-G3 RH Map142702.0UniSTS
G35565  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,646,397 - 73,646,577UniSTSGRCh37
Build 361472,716,150 - 72,716,330RGDNCBI36
Celera1453,709,676 - 53,709,856RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,812,155 - 53,812,335UniSTS
SHGC-31609  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,686,086 - 73,686,287UniSTSGRCh37
Build 361472,755,839 - 72,756,040RGDNCBI36
Celera1453,749,319 - 53,749,520RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,851,600 - 53,851,801UniSTS
TNG Radiation Hybrid Map1426432.0UniSTS
Stanford-G3 RH Map142660.0UniSTS
GeneMap99-GB4 RH Map14191.19UniSTS
Whitehead-RH Map14258.8UniSTS
NCBI RH Map14771.7UniSTS
GeneMap99-G3 RH Map142708.0UniSTS
G38198  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,645,908 - 73,646,009UniSTSGRCh37
Build 361472,715,661 - 72,715,762RGDNCBI36
Celera1453,709,187 - 53,709,288RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,811,666 - 53,811,767UniSTS
G35665  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,623,230 - 73,623,326UniSTSGRCh37
Build 361472,692,983 - 72,693,079RGDNCBI36
Celera1453,686,511 - 53,686,607RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,788,993 - 53,789,089UniSTS
G38129  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,604,805 - 73,604,885UniSTSGRCh37
Build 361472,674,558 - 72,674,638RGDNCBI36
Celera1453,668,091 - 53,668,171RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,770,486 - 53,770,566UniSTS
G38324  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,613,222 - 73,613,379UniSTSGRCh37
Build 361472,682,975 - 72,683,132RGDNCBI36
Celera1453,676,504 - 53,676,661RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,778,898 - 53,779,055UniSTS
G35501  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,649,700 - 73,649,823UniSTSGRCh37
Build 361472,719,453 - 72,719,576RGDNCBI36
Celera1453,712,979 - 53,713,102RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,815,458 - 53,815,581UniSTS
WI-11404  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,679,948 - 73,680,097UniSTSGRCh37
Build 361472,749,701 - 72,749,850RGDNCBI36
Celera1453,743,179 - 53,743,328RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,845,460 - 53,845,609UniSTS
GeneMap99-GB4 RH Map14189.67UniSTS
Whitehead-RH Map14259.0UniSTS
NCBI RH Map14818.9UniSTS
G38176  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,608,298 - 73,608,454UniSTSGRCh37
Build 361472,678,051 - 72,678,207RGDNCBI36
Celera1453,671,580 - 53,671,736RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,773,975 - 53,774,131UniSTS
A005E05  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,690,147 - 73,690,287UniSTSGRCh37
Build 361472,759,900 - 72,760,040RGDNCBI36
Celera1453,753,380 - 53,753,520RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,855,661 - 53,855,801UniSTS
GeneMap99-GB4 RH Map14191.19UniSTS
Whitehead-RH Map14258.8UniSTS
RH77790  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,654,231 - 73,654,380UniSTSGRCh37
Build 361472,723,984 - 72,724,133RGDNCBI36
Celera1453,717,462 - 53,717,611RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,819,682 - 53,819,831UniSTS
GeneMap99-GB4 RH Map14187.83UniSTS
NCBI RH Map14803.2UniSTS
SGC34362  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,654,356 - 73,654,455UniSTSGRCh37
Build 361472,724,109 - 72,724,208RGDNCBI36
Celera1453,717,587 - 53,717,686RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,819,807 - 53,819,906UniSTS
GeneMap99-GB4 RH Map14183.36UniSTS
Whitehead-RH Map14257.6UniSTS
NCBI RH Map14816.7UniSTS
G38323  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,689,786 - 73,690,054UniSTSGRCh37
Build 361472,759,539 - 72,759,807RGDNCBI36
Celera1453,753,019 - 53,753,287RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,855,300 - 53,855,568UniSTS
G38182  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,627,985 - 73,628,134UniSTSGRCh37
Build 361472,697,738 - 72,697,887RGDNCBI36
Celera1453,691,267 - 53,691,416RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,793,744 - 53,793,893UniSTS
G38272  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,680,897 - 73,681,062UniSTSGRCh37
Build 361472,750,650 - 72,750,815RGDNCBI36
Celera1453,744,128 - 53,744,293RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,846,409 - 53,846,574UniSTS
G38184  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,687,932 - 73,688,181UniSTSGRCh37
Build 361472,757,685 - 72,757,934RGDNCBI36
Celera1453,751,165 - 53,751,414RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,853,446 - 53,853,695UniSTS
G38203  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,625,964 - 73,626,131UniSTSGRCh37
Build 361472,695,717 - 72,695,884RGDNCBI36
Celera1453,689,245 - 53,689,412RGD
Cytogenetic Map14q24.3UniSTS
HuRef1453,791,722 - 53,791,889UniSTS
D15S1477  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4q32-q35UniSTS
Cytogenetic Map5q11UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map10p12.1-p11.2UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map12p13.3UniSTS
Cytogenetic Map1q25UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map5q14UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map14q31-q32UniSTS
Cytogenetic Map10q25.2UniSTS
Cytogenetic Map16p13.13-p13.12UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map2p22.1UniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map15q21.1UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map10q24.2UniSTS
Cytogenetic Map1q42.11UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map11q24UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map4q25UniSTS
Cytogenetic Map11q14.2UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map5q23UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map13q12.1UniSTS
Cytogenetic Map6p21.32UniSTS
Cytogenetic Map2q31UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map3p21.2UniSTS
Cytogenetic Map1q21.3UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map8p11.22UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map4q28.2UniSTS
Cytogenetic Map1p13.2UniSTS
Cytogenetic Map22q12.3UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map1p36.21UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map15q11-q13UniSTS
Cytogenetic Map19pUniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map8q11.21UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map10q23.2UniSTS
Cytogenetic Map7p22.3UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map1q31.3UniSTS
Cytogenetic Map4q35UniSTS
Cytogenetic Map9p13UniSTS
Cytogenetic Map3p24.2UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map6q25.2-q25.3UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map7q22.3UniSTS
Cytogenetic Map9q34.2UniSTS
Cytogenetic Map17q24UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map19q13.3-q13.4UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map3q21UniSTS
Cytogenetic Map20q13UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map17q22-q23UniSTS
Cytogenetic MapXp22.33UniSTS
Cytogenetic MapYp11.3UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map12q23.1UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map13q11UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic Map3p25-p24UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic MapXq22.1UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map3p12UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic MapXp11.2UniSTS
Cytogenetic Map11q13.1-q13.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map5p13.2UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map10q23.31UniSTS
Cytogenetic Map6p21.1-p12.2UniSTS
Cytogenetic Map12q14.1UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map11p15.5UniSTS
Cytogenetic Map1p35UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map8q23.1UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map14q11.1UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19p13.3-p13.2UniSTS
Cytogenetic Map1p36.11-p34.2UniSTS
Cytogenetic Map9p22UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map9p22.1UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic Map12q15UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map9q21.13UniSTS
Cytogenetic Map11p15.1UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map12q21.1UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map20p11.23UniSTS
Cytogenetic Map15q15.2UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map8q12.1UniSTS
Cytogenetic Map14q21.2UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map17p13.1UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map12p13.2UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map15q21.3UniSTS
Cytogenetic MapXp11.22UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map18q12.3UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map12q11-q12UniSTS
Cytogenetic Map3q13.33UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map2p24UniSTS
Cytogenetic Map8q24.21UniSTS
Cytogenetic Map12q22-q23.1UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map15q21-q22UniSTS
Cytogenetic Map8p21.2UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map16p13.13UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map10q24UniSTS
Cytogenetic Map8q11.2UniSTS
Cytogenetic Map7p14-p13UniSTS
Cytogenetic Map11q22-q23UniSTS
Cytogenetic Map6q22-q23UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map15q26.3UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map4q21.22UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map16p12.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map11q24.3UniSTS
Cytogenetic Map11q13.1-q13.3UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map17q23.3UniSTS
Cytogenetic Map2q24UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map10q25UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map15q21-q23UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map6p21UniSTS
Cytogenetic Map2p25.2UniSTS
Cytogenetic Map14q23.1UniSTS
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map15q14-q15UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map12p12.1UniSTS
Cytogenetic MapXq25UniSTS
Cytogenetic Map14q23.2UniSTS
Cytogenetic Map11q12UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map5q35UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map6p23UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map3q25.31UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map10q24.31UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map10q22.2UniSTS
Cytogenetic Map6q13UniSTS
Cytogenetic Map10q21.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map4q31.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map18q21.3UniSTS
Cytogenetic Map11q21UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map11q23.2UniSTS
Cytogenetic Map8q12UniSTS
Cytogenetic Map4q28-q32UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map15q21.2UniSTS
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map9q34UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map12q24.11UniSTS
Cytogenetic Map9q21.12UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map11q22.3UniSTS
Cytogenetic Map20p11.22-p11.1UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map2q24.3UniSTS
Cytogenetic Map8p12UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map9q31-q33UniSTS
Cytogenetic Map6p24.1UniSTS
Cytogenetic Map10p11.23UniSTS
Cytogenetic Map6q15UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map3q26.1-q26.2UniSTS
Cytogenetic Map5q11.2-q13.2UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic MapXp11.4UniSTS
Cytogenetic MapXq13.3UniSTS
Cytogenetic Map8q22.2UniSTS
Cytogenetic Map7q11.21UniSTS
Cytogenetic Map5q35.1UniSTS
Cytogenetic Map5q33.1UniSTS
Cytogenetic Map4q21.21UniSTS
Cytogenetic Map2q21.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic MapXq21.1UniSTS
Cytogenetic Map10p11.21UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map5q34UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map12p11.21UniSTS
Cytogenetic Map5q33.3UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map9q31.3UniSTS
Cytogenetic Map15q24UniSTS
Cytogenetic Map11q13.2UniSTS
Cytogenetic Map12q21UniSTS
Cytogenetic Map8p11.2UniSTS
Cytogenetic Map7q22-q31UniSTS
Cytogenetic Map22q12UniSTS
Cytogenetic Map4q22UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map12q14UniSTS
Cytogenetic Map11q23.1-q23.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map13q32.2UniSTS
Cytogenetic Map17qUniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map13q22.1UniSTS
Cytogenetic Map3p25.2UniSTS
Cytogenetic Map5q21.3UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map6p24.2UniSTS
G38133  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371473,604,656 - 73,605,807UniSTSGRCh37
Celera1453,667,942 - 53,669,089UniSTS
Cytogenetic Map14q24.3UniSTS
HuRef1453,770,337 - 53,771,485UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:6756
Count of miRNA genes:1320
Interacting mature miRNAs:1694
Transcripts:ENST00000261970, ENST00000324501, ENST00000344094, ENST00000357710, ENST00000394157, ENST00000394164, ENST00000406768, ENST00000553447, ENST00000553599, ENST00000553719, ENST00000553855, ENST00000554131, ENST00000554995, ENST00000555254, ENST00000555386, ENST00000555867, ENST00000556011, ENST00000556066, ENST00000556533, ENST00000556864, ENST00000556951, ENST00000557037, ENST00000557293, ENST00000557356, ENST00000557511, ENST00000559361, ENST00000560005
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1876 1762 1053 271 1664 138 3505 729 2073 328 1386 1593 150 1 1056 1952 6 2
Low 563 1227 673 353 287 327 852 1466 1661 91 74 20 25 148 836
Below cutoff 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_007386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_007318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005267864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005267866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011536972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011536973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011536974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB159776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF029701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF109907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF205592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF416717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ008005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK223173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303876 (Get FASTA)