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Gene: Psen1 (presenilin 1) Chinchilla lanigera
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Symbol: Psen1
Name: presenilin 1
RGD ID: 8733975
Description: ENCODES a protein that exhibits aspartic endopeptidase activity, intramembrane cleaving (ortholog); ATPase binding (ortholog); beta-catenin binding (ortholog); INVOLVED IN activation of MAPKK activity (ortholog); amyloid precursor protein catabolic process (ortholog); amyloid precursor protein metabolic process (ortholog); PARTICIPATES IN Notch signaling pathway; syndecan signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 3 (ortholog); Alzheimer's disease 4 (ortholog); FOUND IN aggresome (ortholog); axon (ortholog); cell cortex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: presenilin-1
Orthologs:
Homo sapiens (human) : PSEN1 (presenilin 1)  HGNC  Alliance
Mus musculus (house mouse) : Psen1 (presenilin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Psen1 (presenilin 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PSEN1 (presenilin 1)
Canis lupus familiaris (dog) : PSEN1 (presenilin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psen1 (presenilin 1)
Sus scrofa (pig) : PSEN1 (presenilin 1)
Chlorocebus sabaeus (African green monkey) : PSEN1 (presenilin 1)
Heterocephalus glaber (naked mole-rat) : Psen1 (presenilin 1)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555232,128,529 - 2,210,737 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555232,128,529 - 2,210,737 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Psen1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 8733975
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.